GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9H4P4 RNF41 is_active_in GO:0071782 endoplasmic reticulum tubular network cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000393252|UniProtKB:Q9H4P4 9606 Homo sapiens GO_Central E3 ubiquitin-protein ligase NRDP1 20250620 UniProtKB Q9H4P4 RNF41 involved_in GO:0000209 protein polyubiquitination biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00044436 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20260601 UniProtKB Q9H4P4 RNF41 enables GO:0008270 zinc ion binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR013010 9606 Homo sapiens InterPro E3 ubiquitin-protein ligase NRDP1 20260601 UniProtKB Q9H4P4 RNF41 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000501 IEA GO_REF:0000120 InterPro:IPR015036|UniPathway:UPA00143 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20260601 UniProtKB Q9H4P4 RNF41 enables GO:0019899 enzyme binding molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026481 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20260601 UniProtKB Q9H4P4 RNF41 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000501 IEA GO_REF:0000120 InterPro:IPR015036|EC:2.3.2.27 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20260601 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:P35249 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25036637 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:P35249 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q66PJ3-3 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q86U28 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q8N1B4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9BRK4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9NSB8 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9NWX5 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9NX04 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25910212 UniProtKB:Q7LG56 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26496610 UniProtKB:O15049 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q9NWX5 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q9UHY7 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:A0A0C4DG62 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:O15049 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P35249 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P54725 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q6FHY5 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q86U28 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8N1B4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8N3F0 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8N8B7-2 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9GZT4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9NWX5 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9NX04 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9UHY7 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P61086 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q86U28 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q8N1B4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9GZT4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9NWX5 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9UHY7 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:Q99614 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:22493164 UniProtKB:Q9H4P4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9H4P4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:Q9H4P4 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase NRDP1 20260530 UniProtKB Q9H4P4 RNF41 enables GO:0005128 erythropoietin receptor binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BH75|ensembl:ENSMUSP00000100869 9606 Homo sapiens Ensembl E3 ubiquitin-protein ligase NRDP1 20260529 UniProtKB Q9H4P4 RNF41 enables GO:0005135 interleukin-3 receptor binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q8BH75|ensembl:ENSMUSP00000100869 9606 Homo sapiens Ensembl E3 ubiquitin-protein ligase NRDP1 20260529 UniProtKB Q9H4P4 RNF41 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-1358789 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20240514 UniProtKB Q9H4P4 RNF41 enables GO:0019904 protein domain specific binding molecular_function ECO:0000353 IPI PMID:27353365 UniProtKB:Q9NQC3 9606 Homo sapiens CAFA E3 ubiquitin-protein ligase NRDP1 20161019 UniProtKB Q9H4P4 RNF41 enables GO:0030971 receptor tyrosine kinase binding molecular_function ECO:0000353 IPI PMID:27353365 UniProtKB:P21860 9606 Homo sapiens CAFA E3 ubiquitin-protein ligase NRDP1 20161019 UniProtKB Q9H4P4 RNF41 involved_in GO:0045732 positive regulation of protein catabolic process biological_process ECO:0000315 IMP PMID:27353365 9606 Homo sapiens CAFA E3 ubiquitin-protein ligase NRDP1 20161019 UniProtKB Q9H4P4 RNF41 located_in GO:0048471 perinuclear region of cytoplasm cellular_component ECO:0000314 IDA PMID:27353365 9606 Homo sapiens CAFA E3 ubiquitin-protein ligase NRDP1 20161019 UniProtKB Q9H4P4 RNF41 located_in GO:0071782 endoplasmic reticulum tubular network cellular_component ECO:0000314 IDA PMID:27353365 9606 Homo sapiens CAFA E3 ubiquitin-protein ligase NRDP1 20161019 UniProtKB Q9H4P4 RNF41 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:18541373 9606 Homo sapiens ParkinsonsUK-UCL E3 ubiquitin-protein ligase NRDP1 20141218 UniProtKB Q9H4P4 RNF41 enables GO:0031267 small GTPase binding molecular_function ECO:0000353 IPI PMID:24056301 UniProtKB:P11233 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20141204 UniProtKB Q9H4P4 RNF41 enables GO:0031267 small GTPase binding molecular_function ECO:0000353 IPI PMID:24056301 UniProtKB:P11234 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20141204 UniProtKB Q9H4P4 RNF41 involved_in GO:0000209 protein polyubiquitination biological_process ECO:0000314 IDA PMID:18541373 9606 Homo sapiens ParkinsonsUK-UCL E3 ubiquitin-protein ligase NRDP1 20140827 UniProtKB Q9H4P4 RNF41 involved_in GO:0010498 proteasomal protein catabolic process biological_process ECO:0000314 IDA PMID:18541373 9606 Homo sapiens ParkinsonsUK-UCL E3 ubiquitin-protein ligase NRDP1 20140827 UniProtKB Q9H4P4 RNF41 involved_in GO:2000379 positive regulation of reactive oxygen species metabolic process biological_process ECO:0000315 IMP PMID:18541373 9606 Homo sapiens ParkinsonsUK-UCL E3 ubiquitin-protein ligase NRDP1 20140827 UniProtKB Q9H4P4 RNF41 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000314 IDA PMID:24105792 9606 Homo sapiens FlyBase E3 ubiquitin-protein ligase NRDP1 20140404 UniProtKB Q9H4P4 RNF41 involved_in GO:0051865 protein autoubiquitination biological_process ECO:0000314 IDA PMID:24105792 9606 Homo sapiens FlyBase E3 ubiquitin-protein ligase NRDP1 20140404 UniProtKB Q9H4P4 RNF41 involved_in GO:0097191 extrinsic apoptotic signaling pathway biological_process ECO:0000314 IDA PMID:14765125 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20130607 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358789 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358790 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358792 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358795 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358797 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358798 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1358801 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase NRDP1 20130516 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11867753 UniProtKB:Q15303 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20120708 UniProtKB Q9H4P4 RNF41 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation biological_process ECO:0000314 IDA PMID:17145873 9606 Homo sapiens MGI E3 ubiquitin-protein ligase NRDP1 20120618 UniProtKB Q9H4P4 RNF41 acts_upstream_of_or_within GO:0030336 negative regulation of cell migration biological_process ECO:0000315 IMP PMID:17145873 9606 Homo sapiens MGI E3 ubiquitin-protein ligase NRDP1 20120618 UniProtKB Q9H4P4 RNF41 acts_upstream_of_or_within GO:0043408 regulation of MAPK cascade biological_process ECO:0000314 IDA PMID:17145873 9606 Homo sapiens MGI E3 ubiquitin-protein ligase NRDP1 20120618 UniProtKB Q9H4P4 RNF41 acts_upstream_of_or_within GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction biological_process ECO:0000314 IDA PMID:17145873 9606 Homo sapiens MGI E3 ubiquitin-protein ligase NRDP1 20120618 UniProtKB Q9H4P4 RNF41 involved_in GO:2000377 regulation of reactive oxygen species metabolic process biological_process ECO:0000315 IMP PMID:18541373 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20110406 UniProtKB Q9H4P4 RNF41 involved_in GO:0000209 protein polyubiquitination biological_process ECO:0000314 IDA PMID:18541373 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100618 UniProtKB Q9H4P4 RNF41 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000314 IDA PMID:18541373 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100618 UniProtKB Q9H4P4 RNF41 involved_in GO:0000209 protein polyubiquitination biological_process ECO:0000314 IDA PMID:14765125 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100608 UniProtKB Q9H4P4 RNF41 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000314 IDA PMID:14765125 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100608 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14765125 UniProtKB:Q9NR09 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100608 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15314180 UniProtKB:O88738 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100608 UniProtKB Q9H4P4 RNF41 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15314180 UniProtKB:Q80U87 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase NRDP1 20100608