SPRED1 (Sprouty-related, EVH1 domain-containing protein 1) is a non-catalytic, membrane-associated adaptor that negatively regulates growth-factor receptor tyrosine kinase signalling through the Ras-RAF-MEK-ERK (MAPK) cascade. It has an N-terminal EVH1 domain, a central KIT-binding domain (KBD) and a C-terminal cysteine-rich Sprouty (SPR) domain. The EVH1 domain binds the non-catalytic GAPex region of the neurofibromin (NF1) GAP-related domain with high affinity, and the SPR domain (which mediates homo/heterodimerization with SPRED2 and is S-acylated) targets SPRED1 to the inner leaflet of the plasma membrane, including raft/caveolar domains. SPRED1 thereby recruits the RasGAP neurofibromin to membrane-bound Ras, lowering Ras-GTP and downstream ERK activation; SPRED1 itself does not alter NF1 GAP activity. SPRED1 also binds KIT and several kinases (it inhibits the cofilin kinase TESK1 and modulates DYRK1A substrate phosphorylation), and its expression is controlled in endothelial and progenitor cells by miR-126 and miR-1. Heterozygous loss-of-function mutations cause Legius syndrome, a neurofibromatosis type 1-like RASopathy, and SPRED1 loss is a driver in mucosal melanoma.
| GO Term | Evidence | Action | Reason |
|---|---|---|---|
| GO:0005173 stem cell factor receptor binding | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Binding to the receptor tyrosine kinase KIT (stem cell factor receptor). SPRED proteins were originally isolated as KIT/c-Fms-interacting proteins and share a central KIT-binding domain (KBD). Reason: KIT binding via the KBD is well established for SPRED family members (transferred here from mouse Spred1), but its functional consequence is less clear than the NF1-recruitment mechanism. Retain as a non-core binding function. Supporting Evidence: PMID:33872193 This screen identified SPRED1 as a binding partner for the intracellular kinase domain of c-Kit in its inactive state. |
| GO:0005173 stem cell factor receptor binding | ISS GO_REF:0000024 | KEEP AS NON CORE | Summary: Binding to the receptor tyrosine kinase KIT (stem cell factor receptor). SPRED proteins were originally isolated as KIT/c-Fms-interacting proteins and share a central KIT-binding domain (KBD). Reason: KIT binding via the KBD is well established for SPRED family members (transferred here from mouse Spred1), but its functional consequence is less clear than the NF1-recruitment mechanism. Retain as a non-core binding function. Supporting Evidence: PMID:33872193 This screen identified SPRED1 as a binding partner for the intracellular kinase domain of c-Kit in its inactive state. |
| GO:0005515 protein binding | IPI PMID:15231748 Functional proteomics mapping of a human signaling pathway. | REMOVE | Summary: Y2H interaction with protein phosphatase 1 catalytic subunit alpha (PPP1CA) from a high-throughput screen (PMID:15231748). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; no more specific molecular function is supported by this high-throughput screen. The PP1 interaction is better represented by the phosphatase binding annotation from PMID:19389623 (proposed refinement to protein phosphatase 1 binding); its functional significance for SPRED1 is unknown. |
| GO:0005515 protein binding | IPI PMID:19389623 Docking motif-guided mapping of the interactome of protein p... | MODIFY | Summary: SPRED1 identified as a PP1 interactor in an RVxF-motif-guided screen with biochemical validation. Reason: The partner is PPP1CA (P62136). 'protein binding' is uninformative; protein phosphatase 1 binding is the evidence-backed refinement. Abstract-only cache; functional significance for SPRED1 unknown, so this is non-core. Proposed replacements: protein phosphatase 1 binding Supporting Evidence: PMID:19389623 we have identified 78 novel mammalian PP1 interactors |
| GO:0005515 protein binding | IPI PMID:21900206 A directed protein interaction network for investigating int... | REMOVE | Summary: Y2H interaction with CDKN1A (p21) from a directed signalling interaction network screen. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. There is no evidence of a functional SPRED1-p21 relationship. Supporting Evidence: PMID:21900206 we searched for protein interaction partners of more than 450 signaling-related proteins by means of automated yeast two-hybrid interaction mating |
| GO:0005515 protein binding | IPI PMID:22321011 Protein phosphatase 1Ξ± interacting proteins in the human bra... | REMOVE | Summary: Y2H interaction with protein phosphatase 1 catalytic subunit alpha (PPP1CA) from a high-throughput screen (PMID:22321011). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; no more specific molecular function is supported by this high-throughput screen. The PP1 interaction is better represented by the phosphatase binding annotation from PMID:19389623 (proposed refinement to protein phosphatase 1 binding); its functional significance for SPRED1 is unknown. |
| GO:0005515 protein binding | IPI PMID:24705354 The palmitoyl acyltransferase HIP14 shares a high proportion... | REMOVE | Summary: SPRED1 interacts with the palmitoyl acyltransferase ZDHHC17/HIP14 and is palmitoylated by it. Reason: This is an enzyme-substrate interaction in which SPRED1 is the substrate of ZDHHC17. 'protein binding' is uninformative and SPRED1 contributes no molecular function here; the relevant fact (SPRED1 is S-acylated) is a property of the protein, not a GO MF. Removal does not dispute the interaction. Supporting Evidence: PMID:24705354 We confirmed that three of them, GPM6A, and the Sprouty domain-containing proteins SPRED1 and SPRED3, are indeed palmitoylated by HIP14 |
| GO:0005515 protein binding | IPI PMID:26635368 Interaction between a Domain of the Negative Regulator of th... | MODIFY | Summary: Hirata et al. mapped the SPRED1 EVH1 domain binding to the N- and C-terminal helices of the neurofibromin GAP-related domain (GRD) by Y2H and co-IP, and Legius-syndrome EVH1 mutations that reduced binding also lost ERK suppression. Reason: Interaction with neurofibromin (NF1, P21359) is the central mechanistic interaction of SPRED1, but 'protein binding' does not say what NF1 is. GTPase activating protein binding captures the specific partner class; the functional consequence (membrane recruitment of the RasGAP) is captured by the proposed core MF protein-membrane adaptor activity. Proposed replacements: GTPase activating protein binding Supporting Evidence: PMID:26635368 These data clearly demonstrate that SPRED1 inhibits the Ras-ERK pathway by recruiting neurofibromin to Ras through the EVH1-GRD interaction PMID:27313208 Here we show that the EVH1 domain of Spred1 binds to the noncatalytic (GAPex) portion of the GAP-related domain (GRD) of neurofibromin. |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32296183 A reference map of the human binary protein interactome. | REMOVE | Summary: Binary Y2H interaction from the HuRI human reference interactome. Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. Supporting Evidence: PMID:32296183 We screened this search space a total of nine times with a panel of three Y2H assay versions |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005515 protein binding | IPI PMID:32814053 Interactome Mapping Provides a Network of Neurodegenerative ... | REMOVE | Summary: High-throughput yeast two-hybrid interaction from a neurodegenerative-disease-focused interactome screen (Haenig et al. 2020). Reason: GO:0005515 protein binding is uninformative about SPRED1 function. Removal does not dispute the reported interaction; the partner is not a known functional partner of SPRED1 and no more specific molecular function is supported by this high-throughput screen. The cached record is abstract-only; the interaction itself is not adjudicated here. Supporting Evidence: PMID:32814053 generated by systematic yeast two-hybrid |
| GO:0005634 nucleus | EXP PMID:16115197 The Sprouty-related protein, Spred-1, localizes in a lipid r... | UNDECIDED | Summary: UniProt records nuclear localization of SPRED1 from Nonami et al. 2005. Reason: The cached record is abstract-only; the abstract reports raft/caveola localization but says nothing about nuclear SPRED1, and no nuclear function of SPRED1 is known. I cannot verify the experimental basis, so per project rules this is UNDECIDED rather than REMOVE. Supporting Evidence: PMID:16115197 In this study, we demonstrated that Spred-1 localized in cholesterol-rich membrane raft/caveola fractions and interacted with Cav-1. |
| GO:0005634 nucleus | IEA GO_REF:0000044 | UNDECIDED | Summary: UniProt SubCell mapping (Nucleus) derived from the same UniProt statement based on PMID:16115197. Reason: Mirrors the unverifiable EXP nucleus annotation (abstract-only source). No nuclear function of SPRED1 is known; HPA also reports nucleoplasm. Undecided pending access to the full text. |
| GO:0005654 nucleoplasm | IDA GO_REF:0000052 | KEEP AS NON CORE | Summary: Human Protein Atlas immunofluorescence localizes SPRED1 to nucleoplasm. Reason: HPA IDA observation; antibody-based nuclear signal is not connected to any known SPRED1 function, which is exerted at the plasma membrane. Retained as non-core pending orthogonal validation. |
| GO:0005737 cytoplasm | IEA GO_REF:0000107 | ACCEPT | Summary: Cytoplasm, transferred from rat Spred1 via Ensembl Compara. Reason: SPRED1 is a soluble cytoplasmic protein that associates peripherally with the plasma membrane; cytosolic localization is shown directly in PMID:18216281. Supporting Evidence: PMID:18216281 YFP- or cyan fluorescent protein (CFP)-tagged Spred1 protein was mainly located in the cytosol, around the centrosome, and partially at the plasma membrane |
| GO:0005829 cytosol | IDA PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | ACCEPT | Summary: Fluorescently tagged SPRED1 was mainly cytosolic in CHO cells, with partial plasma membrane localization. Reason: Direct observation; SPRED1 cycles between the cytosol and the plasma membrane (B-RAF/RAF dimerization-induced translocation). Supporting Evidence: PMID:18216281 YFP- or cyan fluorescent protein (CFP)-tagged Spred1 protein was mainly located in the cytosol, around the centrosome, and partially at the plasma membrane PMID:33872193 Additionally, SPRED1 associates with B-Raf in the cytoplasm, where B-Raf/C-Raf dimerization induces SPRED1 membrane translocation to the plasma membrane (SiljamΓ€ki and Abankwa 2016). |
| GO:0005829 cytosol | TAS Reactome:R-HSA-5654510 | ACCEPT | Summary: Reactome reaction 'FGFRL1 binds SPRED1/2' places SPRED1 in the cytosol. Reason: A cytosolic pool of SPRED1 is directly observed (IDA, PMID:18216281) and SPRED1 shuttles between cytosol and plasma membrane; the location is correct even though the FGFRL1 interaction itself is co-IP-only and minor. Supporting Evidence: Reactome:R-HSA-5654510 FGFRL1 binds to SPRED1 and 2 and Sprouty1 as assessed by co-immunoprecipitation PMID:18216281 YFP- or cyan fluorescent protein (CFP)-tagged Spred1 protein was mainly located in the cytosol, around the centrosome, and partially at the plasma membrane |
| GO:0005886 plasma membrane | EXP PMID:16115197 The Sprouty-related protein, Spred-1, localizes in a lipid r... | ACCEPT | Summary: Nonami et al. localized SPRED1 to cholesterol-rich plasma membrane raft/caveola fractions. Reason: Plasma membrane is the site of the core function (NF1 recruitment to Ras); confirmed by Stowe et al. 2012. Supporting Evidence: PMID:16115197 In this study, we demonstrated that Spred-1 localized in cholesterol-rich membrane raft/caveola fractions and interacted with Cav-1. PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. |
| GO:0005886 plasma membrane | IBA GO_REF:0000033 | ACCEPT | Summary: PAINT IBA: plasma membrane is the conserved active location of the Sprouty/SPRED family. Reason: Well supported for SPRED1: the C-terminal SPR domain targets SPRED1 to the plasma membrane, where it recruits neurofibromin to Ras. Supporting Evidence: PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | IEA GO_REF:0000120 | ACCEPT | Summary: Plasma membrane, transferred from rat Spred1 (IEA). Reason: Consistent with direct evidence for SPRED1 SPR-domain-dependent plasma membrane localization. Supporting Evidence: PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. |
| GO:0005886 plasma membrane | ISS GO_REF:0000024 | ACCEPT | Summary: Plasma membrane, transferred from rat Spred1 (ISS). Reason: Consistent with direct evidence for SPRED1 SPR-domain-dependent plasma membrane localization. Supporting Evidence: PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-5658231 | ACCEPT | Summary: Reactome (Reactome:R-HSA-5658231) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-5658424 | ACCEPT | Summary: Reactome (Reactome:R-HSA-5658424) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-5658430 | ACCEPT | Summary: Reactome (Reactome:R-HSA-5658430) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-5658435 | ACCEPT | Summary: Reactome (Reactome:R-HSA-5658435) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-5658438 | ACCEPT | Summary: Reactome (Reactome:R-HSA-5658438) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005886 plasma membrane | TAS Reactome:R-HSA-6802837 | ACCEPT | Summary: Reactome (Reactome:R-HSA-6802837) places SPRED1 (in a SPRED:NF1 complex) at the plasma membrane in the NF1/RasGAP reactions. Reason: Accurately reflects the SPRED1-mediated recruitment of NF1 to the plasma membrane. Supporting Evidence: Reactome:R-HSA-5658438 Sprouty-related proteins (SPRED) 1, 2 and 3 are negative regulators of the MAPK pathway that act at least in part by recruiting the RAS GAP protein neurofibromin 1 (NF1) to the plasma membrane PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. |
| GO:0005901 caveola | IEA GO_REF:0000044 | KEEP AS NON CORE | Summary: UniProt SubCell mapping (Membrane, caveola) based on Nonami et al. 2005, who found SPRED1 in cholesterol-rich raft/caveola fractions interacting with caveolin-1. Reason: Supported by fractionation and CAV1 co-IP; raft/caveolar partitioning is a sub-compartment of the plasma membrane where SPRED1 acts, but the general plasma membrane term is the best-supported location of the core function. Supporting Evidence: PMID:16115197 In this study, we demonstrated that Spred-1 localized in cholesterol-rich membrane raft/caveola fractions and interacted with Cav-1. |
| GO:0009966 regulation of signal transduction | IEA GO_REF:0000002 | ACCEPT | Summary: InterPro2GO mapping from the Sprouty domain (IPR007875) to regulation of signal transduction. Reason: Correct, if general: Sprouty-domain proteins regulate RTK-Ras-ERK signalling. More specific negative-regulation terms are annotated elsewhere. Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. |
| GO:0010719 negative regulation of epithelial to mesenchymal transition | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Negative regulation of epithelial to mesenchymal transition, transferred from mouse Spred1 (TGF-beta-induced EMT in lens epithelial cells). Reason: Plausible tissue-level consequence of SPRED-mediated suppression of growth-factor/ERK signalling in lens epithelium (mouse); a downstream physiological outcome rather than the core activity. |
| GO:0010719 negative regulation of epithelial to mesenchymal transition | ISS GO_REF:0000024 | KEEP AS NON CORE | Summary: Negative regulation of epithelial to mesenchymal transition, transferred from mouse Spred1 (TGF-beta-induced EMT in lens epithelial cells). Reason: Plausible tissue-level consequence of SPRED-mediated suppression of growth-factor/ERK signalling in lens epithelium (mouse); a downstream physiological outcome rather than the core activity. |
| GO:0016020 membrane | IEA GO_REF:0000002 | ACCEPT | Summary: InterPro2GO mapping from the Sprouty domain to membrane. Reason: Correct but general; SPRED1 is a peripheral plasma membrane protein targeted by its C-terminal SPR domain. Supporting Evidence: PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. |
| GO:0016525 negative regulation of angiogenesis | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Negative regulation of angiogenesis, transferred from mouse Spred1 (Ensembl Compara). Reason: Consistent with SPRED1 restraining VEGF-ERK signalling in endothelial cells; a physiological consequence of the core activity. Supporting Evidence: PMID:18694566 miR-126 functioned in part by directly repressing negative regulators of the VEGF pathway, including the Sprouty-related protein SPRED1 and phosphoinositol-3 kinase regulatory subunit 2 (PIK3R2/p85-beta). |
| GO:0016525 negative regulation of angiogenesis | IMP PMID:23136161 Loss of angiomiR-126 and 130a in angiogenic early outgrowth ... | KEEP AS NON CORE | Summary: Jakob et al.: loss of miR-126 in angiogenic early outgrowth cells from heart-failure patients impairs their neovascularization capacity; the full text (not cached) reports the SPRED1 knockdown experiments on which this IMP rests. Reason: Abstract-only cache; deferring to the curator who read the full text. Consistent with the established miR-126/SPRED1 axis restraining VEGF-ERK signalling. A physiological outcome of the core ERK-inhibitory activity, so non-core. Supporting Evidence: PMID:23136161 Reduced miR-126 expression was identified as a novel mechanism limiting their capacity to improve cardiac neovascularization and function that can be targeted by miR-126 mimic transfection. |
| GO:0019901 protein kinase binding | IBA GO_REF:0000033 | KEEP AS NON CORE | Summary: PAINT IBA: protein kinase binding across the SPRED/Sprouty family. Reason: Sprouty/SPRED proteins bind several kinases (KIT, RAF, TESK1, DYRK1A); correct at the family level, but kinase binding is not the activity by which SPRED1 suppresses Ras-ERK (that is NF1 recruitment). Supporting Evidence: PMID:33872193 This screen identified SPRED1 as a binding partner for the intracellular kinase domain of c-Kit in its inactive state. PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. |
| GO:0019901 protein kinase binding | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Protein kinase binding, transferred from mouse Spred1. Reason: Correct (KIT, TESK1, DYRK1A binding) but peripheral to the core NF1-recruitment mechanism. Supporting Evidence: PMID:33872193 This screen identified SPRED1 as a binding partner for the intracellular kinase domain of c-Kit in its inactive state. |
| GO:0019901 protein kinase binding | IPI PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | KEEP AS NON CORE | Summary: Y2H/co-IP and pull-down interaction of SPRED1 with the kinases MARKK/TAOK1 and TESK1 (rat partner UniProtKB:O88664). Reason: Direct kinase binding is shown. TESK1 binding inhibits TESK1 (captured by the kinase-inhibitor MF), whereas MARKK binding has no effect on MARKK activity. Peripheral to the Ras-ERK role. Supporting Evidence: PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. PMID:18216281 Spred1-MARKK binding has no effect on the activity of MARKK |
| GO:0019901 protein kinase binding | IPI PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | KEEP AS NON CORE | Summary: Y2H/co-IP and pull-down interaction of SPRED1 with the kinases MARKK/TAOK1 and TESK1 (rat partner UniProtKB:Q63572). Reason: Direct kinase binding is shown. TESK1 binding inhibits TESK1 (captured by the kinase-inhibitor MF), whereas MARKK binding has no effect on MARKK activity. Peripheral to the Ras-ERK role. Supporting Evidence: PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. PMID:18216281 Spred1-MARKK binding has no effect on the activity of MARKK |
| GO:0019901 protein kinase binding | IPI PMID:20736167 Direct association of Sprouty-related protein with an EVH1 d... | KEEP AS NON CORE | Summary: Direct interaction of the SPRED1 cysteine-rich domain with the DYRK1A kinase domain. Reason: Abstract supports direct, endogenous SPRED1-DYRK1A binding; a secondary activity relative to Ras-ERK regulation. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. |
| GO:0019902 phosphatase binding | IDA PMID:19389623 Docking motif-guided mapping of the interactome of protein p... | MODIFY | Summary: SPRED1 identified as a protein phosphatase 1 (PP1) interactor in an RVxF-docking-motif-guided screen with biochemical validation. Reason: Correct but general; the paper is specifically about PP1. Refine to protein phosphatase 1 binding. Functional significance of the PP1 interaction for SPRED1 is unknown (non-core). Abstract-only cache; deferring to the curator on the experimental result. Proposed replacements: protein phosphatase 1 binding Supporting Evidence: PMID:19389623 we have identified 78 novel mammalian PP1 interactors |
| GO:0030291 protein serine/threonine kinase inhibitor activity | IDA PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | ACCEPT | Summary: GST-SPRED1 dose-dependently inhibited TESK1 phosphorylation of cofilin in vitro, and SPRED1 co-expression blocked TESK1-induced stress fibres. Reason: Direct in vitro inhibition of the Ser/Thr kinase TESK1 is shown, paralleling SPRY4. Accepted as a genuine secondary core activity (actin cytoskeleton regulation), distinct from the primary Ras-ERK feedback function. Supporting Evidence: PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. |
| GO:0030291 protein serine/threonine kinase inhibitor activity | IEA GO_REF:0000107 | ACCEPT | Summary: Ser/Thr kinase inhibitor activity (IEA), based on SPRED inhibition of DYRK1A substrate phosphorylation. Reason: SPREDs compete with substrates for the DYRK1A kinase domain, reducing Tau/STAT3 phosphorylation; together with direct TESK1 inhibition this supports a secondary kinase-inhibitor activity. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. |
| GO:0030291 protein serine/threonine kinase inhibitor activity | ISS PMID:20736167 Direct association of Sprouty-related protein with an EVH1 d... | ACCEPT | Summary: Ser/Thr kinase inhibitor activity (ISS), based on SPRED inhibition of DYRK1A substrate phosphorylation. Reason: SPREDs compete with substrates for the DYRK1A kinase domain, reducing Tau/STAT3 phosphorylation; together with direct TESK1 inhibition this supports a secondary kinase-inhibitor activity. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. PMID:18216281 From these results, we conclude that Spred1 inhibits TESK1 activity by binding to it, similar to Sprouty4. |
| GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Negative regulation of TGF-beta receptor signalling, transferred from mouse Spred1 (lens epithelial EMT studies). Reason: Reported for mouse Spred in lens epithelium; mechanism (likely via ERK crosstalk) is not established and SPRED1 has no known direct role in the TGF-beta receptor pathway. Retain as non-core. |
| GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway | ISS GO_REF:0000024 | KEEP AS NON CORE | Summary: Negative regulation of TGF-beta receptor signalling, transferred from mouse Spred1 (lens epithelial EMT studies). Reason: Reported for mouse Spred in lens epithelium; mechanism (likely via ERK crosstalk) is not established and SPRED1 has no known direct role in the TGF-beta receptor pathway. Retain as non-core. |
| GO:0031410 cytoplasmic vesicle | IDA PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | KEEP AS NON CORE | Summary: In CHO cells co-overexpressing TESK1, SPRED1 redistributed from a homogeneous cytosolic distribution into TESK1-containing vesicle-like structures. Reason: The colocalizes_with qualifier is appropriate: the vesicular pattern is induced by TESK1 co-overexpression, and the vesicles did not colocalize with lysosomal, mitochondrial or endosomal markers. Not a site of the core function. Supporting Evidence: PMID:18216281 Thus, it seems that coexpression of TESK1 forces Spred1 to redistribute from a homogeneous cytosolic distribution to vesicle-like TESK1-containing structures |
| GO:0043408 regulation of MAPK cascade | TAS PMID:18216281 Spred1 and TESK1--two new interaction partners of the kinase... | MODIFY | Summary: Traceable author statement that SPRED1 regulates the MAPK cascade. Reason: Correct in direction and essence, but SPRED1 is specifically a negative regulator of the Ras-ERK1/2 cascade; the more precise term is negative regulation of ERK1 and ERK2 cascade. Proposed replacements: negative regulation of ERK1 and ERK2 cascade Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. PMID:22751498 Here we show that neurofibromin, the NF1 gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function. |
| GO:0043409 negative regulation of MAPK cascade | IMP PMID:18694566 miR-126 regulates angiogenic signaling and vascular integrit... | ACCEPT | Summary: Fish et al. showed that miR-126 represses SPRED1 in endothelial cells; Spred1 overexpression reduced phospho-ERK in zebrafish and COS-1 cells, and SPRED1 knockdown rescued VEGF signalling after miR-126 loss. Reason: SPRED1 is an established negative regulator of the Ras-MAPK (ERK) cascade. The more specific ERK1/2 term is also annotated. Supporting Evidence: PMID:18694566 miR-126 functioned in part by directly repressing negative regulators of the VEGF pathway, including the Sprouty-related protein SPRED1 and phosphoinositol-3 kinase regulatory subunit 2 (PIK3R2/p85-beta). PMID:18694566 Additionally, transfection of COS-1 cells with an expression construct containing zebrafish spred1 cDNA resulted in dramatically reduced levels of phosphorylated ERK, confirming that zebrafish Spred1, like its mammalian counterpart, negatively regulates the MAP kinase pathway |
| GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator | IEA GO_REF:0000107 | UNDECIDED | Summary: Positive regulation of DNA damage response, signal transduction by p53 class mediator (IEA, from mouse Spred1; cites PMID:20736167 for the ISS row). Reason: The cited DYRK1A paper is abstract-only in the cache and its abstract mentions only Tau and STAT3 phosphorylation, not p53; no other SPRED1 literature I reviewed connects SPRED1 to p53 DNA-damage signalling. I cannot verify the basis of the source annotation, so this is undecided rather than removed. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. |
| GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator | ISS PMID:20736167 Direct association of Sprouty-related protein with an EVH1 d... | UNDECIDED | Summary: Positive regulation of DNA damage response, signal transduction by p53 class mediator (ISS, from mouse Spred1; cites PMID:20736167 for the ISS row). Reason: The cited DYRK1A paper is abstract-only in the cache and its abstract mentions only Tau and STAT3 phosphorylation, not p53; no other SPRED1 literature I reviewed connects SPRED1 to p53 DNA-damage signalling. I cannot verify the basis of the source annotation, so this is undecided rather than removed. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. |
| GO:0060979 vasculogenesis involved in coronary vascular morphogenesis | IMP PMID:23625462 MicroRNA-1 enhances the angiogenic differentiation of human ... | MODIFY | Summary: van Mil et al.: miR-1 directly represses SPRED1 in human cardiomyocyte progenitor cells (hCMPCs); SPRED1 knockdown phenocopied miR-1 upregulation, i.e. enhanced vascular tube formation and motility in vitro. Reason: The phenotype (knockdown enhances in vitro tube formation) indicates SPRED1 restrains vascular differentiation, so a positive involved_in annotation to an in vivo coronary vasculogenesis term both inverts the direction and over-specifies the anatomical context (in vitro Matrigel/collagen assays on progenitor cells). Negative regulation of vasculogenesis better reflects the abstract; this remains a non-core, context-specific consequence of ERK suppression. Proposed replacements: negative regulation of vasculogenesis Supporting Evidence: PMID:23625462 Knocking down Spred1 phenocopies the functional effect seen for miR-1 upregulation. |
| GO:0070373 negative regulation of ERK1 and ERK2 cascade | IBA GO_REF:0000033 | ACCEPT | Summary: Negative regulation of ERK1 and ERK2 cascade (IBA). Reason: This is the core biological role of SPRED1: it suppresses growth-factor-induced Ras-ERK activation by recruiting the RasGAP neurofibromin to the plasma membrane. Legius-syndrome mutations abolish this activity. The IBA reflects a family-wide Sprouty/SPRED function placed by PAINT. Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. PMID:22751498 Here we show that neurofibromin, the NF1 gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function. PMID:26635368 These data clearly demonstrate that SPRED1 inhibits the Ras-ERK pathway by recruiting neurofibromin to Ras through the EVH1-GRD interaction |
| GO:0070373 negative regulation of ERK1 and ERK2 cascade | IEA GO_REF:0000107 | ACCEPT | Summary: Negative regulation of ERK1 and ERK2 cascade (IEA). Reason: This is the core biological role of SPRED1: it suppresses growth-factor-induced Ras-ERK activation by recruiting the RasGAP neurofibromin to the plasma membrane. Legius-syndrome mutations abolish this activity. Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. PMID:22751498 Here we show that neurofibromin, the NF1 gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function. PMID:26635368 These data clearly demonstrate that SPRED1 inhibits the Ras-ERK pathway by recruiting neurofibromin to Ras through the EVH1-GRD interaction |
| GO:0070373 negative regulation of ERK1 and ERK2 cascade | ISS GO_REF:0000024 | ACCEPT | Summary: Negative regulation of ERK1 and ERK2 cascade (ISS). Reason: This is the core biological role of SPRED1: it suppresses growth-factor-induced Ras-ERK activation by recruiting the RasGAP neurofibromin to the plasma membrane. Legius-syndrome mutations abolish this activity. Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. PMID:22751498 Here we show that neurofibromin, the NF1 gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function. PMID:26635368 These data clearly demonstrate that SPRED1 inhibits the Ras-ERK pathway by recruiting neurofibromin to Ras through the EVH1-GRD interaction |
| GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Negative regulation of cell migration involved in sprouting angiogenesis, transferred from mouse Spred1. Reason: Consistent with SPRED1 restraining VEGF-ERK signalling in endothelial cells (miR-126/SPRED1 axis); a physiological consequence rather than the core activity. Supporting Evidence: PMID:18694566 miR-126 functioned in part by directly repressing negative regulators of the VEGF pathway, including the Sprouty-related protein SPRED1 and phosphoinositol-3 kinase regulatory subunit 2 (PIK3R2/p85-beta). |
| GO:1902532 negative regulation of intracellular signal transduction | IEA GO_REF:0000120 | ACCEPT | Summary: ARBA/Ensembl transfer of negative regulation of intracellular signal transduction. Reason: Correct general parent of SPRED1's negative regulation of the Ras-ERK cascade. Supporting Evidence: PMID:11493923 Like Sprouty, Spred inhibited growth-factor-mediated activation of MAP kinase. |
| GO:1902532 negative regulation of intracellular signal transduction | IMP PMID:20736167 Direct association of Sprouty-related protein with an EVH1 d... | ACCEPT | Summary: Li et al.: SPRED1 (and SPRED2) directly bind DYRK1A and reduce its phosphorylation of Tau and STAT3; IMP presumably from SPRED knockdown experiments in the full text. Reason: Broad but correct: SPRED1 negatively regulates intracellular signalling (Ras-ERK and DYRK1A-substrate phosphorylation). Abstract-only cache; deferring to curator on the experimental detail. Supporting Evidence: PMID:20736167 Both SPRED1 and SPRED2 inhibit the ability of DYRK1A to phosphorylate its substrates, Tau and STAT3. |
| GO:1902747 negative regulation of lens fiber cell differentiation | IEA GO_REF:0000107 | KEEP AS NON CORE | Summary: Negative regulation of lens fiber cell differentiation, from mouse Spred1 (inhibition of FGF-induced lens fiber differentiation). Reason: Supported by mouse studies of Spred inhibition of FGF-ERK signalling in the lens (UniProt function statement, by similarity); tissue-specific consequence of the core ERK-inhibitory activity. |
| GO:1902747 negative regulation of lens fiber cell differentiation | ISS GO_REF:0000024 | KEEP AS NON CORE | Summary: Negative regulation of lens fiber cell differentiation, from mouse Spred1 (inhibition of FGF-induced lens fiber differentiation). Reason: Supported by mouse studies of Spred inhibition of FGF-ERK signalling in the lens (UniProt function statement, by similarity); tissue-specific consequence of the core ERK-inhibitory activity. |
| GO:0043495 protein-membrane adaptor activity | IDA PMID:22751498 A shared molecular mechanism underlies the human rasopathies... | NEW | Summary: SPRED1 binds neurofibromin via its EVH1 domain and, via its C-terminal SPR domain, brings it to the plasma membrane where NF1 inactivates Ras; membrane targeting (rescued by a CAAX fusion) and NF1 binding are both required. Reason: This is the molecular activity by which SPRED1 suppresses Ras-ERK signalling and is not represented by any existing annotation (only 'protein binding' to NF1). SPRED1 itself performs the work: it is the bridge between NF1 and the membrane; NF1 performs GAP catalysis, and SPRED1 does not alter GAP activity. Supported by cell biology (Stowe 2012), biochemistry (Dunzendorfer-Matt 2016) and structure (Yan 2020). Supporting Evidence: PMID:22751498 We show that Spred1 binding induces the plasma membrane localization of NF1, which subsequently down-regulates Ras-GTP levels. PMID:22751498 Together, these results underscore the importance of the EVH1 domain of Spred1 in inhibiting ERK activation, and the importance of the SPR domain in directing the plasma membrane localization of Spred1. PMID:27313208 Binding is compatible with simultaneous binding of Ras and does not interfere with GAP activity. PMID:32697994 This inhibition of RAS is thought to occur primarily through SPRED1 binding and recruitment of neurofibromin, a RasGAP, to the plasma membrane. file:human/SPRED1/SPRED1-deep-research-falcon.md SPRED1 therefore has no catalytic reaction, enzyme substrate specificity or transport substrate of its own. |
| GO:0046580 negative regulation of Ras protein signal transduction | IMP PMID:22751498 A shared molecular mechanism underlies the human rasopathies... | NEW | Summary: SPRED1 overexpression reduced and SPRED1 depletion increased EGF-stimulated Ras-GTP levels; the effect requires neurofibromin. Reason: SPRED1 acts at the level of Ras itself (Ras-GTP), upstream of RAF/ERK, by delivering the RasGAP NF1 to membrane Ras. Participation test: SPRED1 performs the adaptor/recruitment step that the GAP-catalysed inactivation depends on (scaffold-type contribution). Comparator check: the Sprouty feedback regulators SPRY1, SPRY2 and SPRY4 carry this term (IBA), as does NF1 (IEA); SPRED1 lacks it only because SPREDs sit in a separate PANTHER family (PTHR11202). Supporting Evidence: PMID:22751498 Inducible expression of Spred1 in T-REx-293 cells significantly reduced Ras-GTP levels following EGF stimulation, suggesting that Spred1 might interfere with Ras regulation. PMID:22751498 Depletion of Spred1 from the PC3 prostate cell line resulted in elevated levels of Ras-GTP following EGF stimulation. PMID:22751498 Here we show that neurofibromin, the NF1 gene product, is a Spred1-interacting protein that is necessary for Spred1's inhibitory function. |
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Download this section (compressed HTML)Q: Does SPRED1 also inhibit RAF activation independently of neurofibromin (as originally proposed by Wakioka et al. 2001), or is all of its ERK-suppressive activity NF1-dependent in physiological settings?
Q: What is the physiological role of SPRED1 binding to KIT via the KBD, and does KIT-dependent tyrosine phosphorylation regulate NF1 recruitment?
Q: Is the reported nuclear/nucleoplasmic SPRED1 signal real and functional, or an antibody/overexpression artefact?
Q: Which zDHHC enzymes S-acylate endogenous SPRED1 and does acylation (versus SPR-domain lipid/caveolin binding) determine membrane targeting?
Experiment: Compare ERK and Ras-GTP suppression by wild-type SPRED1 in NF1-null versus NF1-reconstituted isogenic cells to quantify any NF1-independent (e.g. RAF-directed) activity.
Experiment: Endogenous tagging of SPRED1 (CRISPR knock-in) with live imaging to determine its native distribution between plasma membrane, cytosol and nucleus under growth-factor stimulation.
Experiment: Map S-acylation sites in the SPR domain and test acylation-deficient mutants for membrane localization and NF1 recruitment.
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