GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103034|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|MGI:MGI:103039|MGI:MGI:103062|MGI:MGI:103063|PANTHER:PTN000210448|RGD:3772|UniProtKB:P40763|UniProtKB:P42224|UniProtKB:P42226|UniProtKB:P42229|UniProtKB:P51692|UniProtKB:P52630|UniProtKB:Q14765|WB:WBGene00010251|WB:WBGene00013111|dictyBase:DDB_G0268638|dictyBase:DDB_G0281381|dictyBase:DDB_G0293532 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20250411 UniProtKB P42224 STAT1 enables GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103034|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103062|PANTHER:PTN000210448|UniProtKB:P40763|UniProtKB:P42224 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20241120 UniProtKB P42224 STAT1 involved_in GO:0006357 regulation of transcription by RNA polymerase II biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:103034|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|MGI:MGI:103062|PANTHER:PTN000210448|RGD:1309063|RGD:3772|UniProtKB:P40763|UniProtKB:P42224|UniProtKB:P42226|UniProtKB:P52630|WB:WBGene00013111|ZFIN:ZDB-GENE-030820-2 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20241120 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103063|PANTHER:PTN000927860|RGD:3771|RGD:3773|RGD:3774|UniProtKB:P40763|UniProtKB:P42224|UniProtKB:P42226|UniProtKB:P52630|ZFIN:ZDB-GENE-030820-2|ZFIN:ZDB-GENE-980526-68 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20241120 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|MGI:MGI:103062|MGI:MGI:103063|PANTHER:PTN000210448|UniProtKB:P40763|UniProtKB:P42224|UniProtKB:P42226|UniProtKB:P51692|UniProtKB:P52630 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20240729 UniProtKB P42224 STAT1 involved_in GO:0006952 defense response biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|MGI:MGI:103039|MGI:MGI:103063|PANTHER:PTN000927860|RGD:3772|RGD:3774|UniProtKB:P42224|UniProtKB:P52630|ZFIN:ZDB-GENE-030131-9359 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20240205 UniProtKB P42224 STAT1 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103034|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|MGI:MGI:103039|MGI:MGI:103063|PANTHER:PTN000210448|RGD:3772|UniProtKB:P40763|UniProtKB:P42224|UniProtKB:P42226|UniProtKB:P42229|UniProtKB:P51692|UniProtKB:P52630|WB:WBGene00010251|WB:WBGene00013111|dictyBase:DDB_G0281381|dictyBase:DDB_G0293532 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20231129 UniProtKB P42224 STAT1 part_of GO:0070721 ISGF3 complex cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN002623830|UniProtKB:P42224 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20231129 UniProtKB P42224 STAT1 involved_in GO:0042127 regulation of cell population proliferation biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0016917|MGI:MGI:103034|MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|PANTHER:PTN000927860|RGD:3771|RGD:3772|RGD:3774|UniProtKB:P42224|UniProtKB:P42229|ZFIN:ZDB-GENE-980526-68|dictyBase:DDB_G0268638 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20220922 UniProtKB P42224 STAT1 involved_in GO:0043434 response to peptide hormone biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:103035|MGI:MGI:103036|MGI:MGI:103038|PANTHER:PTN000210451|RGD:3771|RGD:3772|RGD:3774|UniProtKB:P40763|UniProtKB:P51692 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20190221 UniProtKB P42224 STAT1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:103063|PANTHER:PTN002623830|UniProtKB:P42224 9606 Homo sapiens GO_Central Signal transducer and activator of transcription 1-alpha/beta 20190221 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00029016 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 enables GO:0003677 DNA binding molecular_function ECO:0000501 IEA GO_REF:0000120 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183|InterPro:IPR013801|UniProtKB-KW:KW-0238 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 enables GO:0003700 DNA-binding transcription factor activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR001217|InterPro:IPR008967|InterPro:IPR022752 9606 Homo sapiens InterPro Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026290 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00029243 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0006355 regulation of DNA-templated transcription biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR001217|InterPro:IPR008967|InterPro:IPR013799|InterPro:IPR013800|InterPro:IPR015988 9606 Homo sapiens InterPro Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0007165 signal transduction biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR001217|InterPro:IPR013799|InterPro:IPR013800|InterPro:IPR015988 9606 Homo sapiens InterPro Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0042981 regulation of apoptotic process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027086 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0051093 negative regulation of developmental process biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027583 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0051607 defense response to virus biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026923|UniProtKB-KW:KW-0051 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0060333 type II interferon-mediated signaling pathway biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00090813 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00033815 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 part_of GO:0090575 RNA polymerase II transcription regulator complex cellular_component ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00028248 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250901 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11238845 UniProtKB:P07239 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12070153 UniProtKB:P00533 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12788789 UniProtKB:P01100 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15780933 UniProtKB:P15260 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15825084 UniProtKB:P27958-PRO_0000037566 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15825084 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16189514 UniProtKB:Q8N9N8 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16273093 UniProtKB:P04626 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16940534 UniProtKB:P26664 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17275127 UniProtKB:P27958-PRO_0000037576 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17596301 UniProtKB:P52294 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17923090 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20195357 UniProtKB:Q01094 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20576130 UniProtKB:Q05397 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q7Z434 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:P19793 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q16531 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24065129 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24360797 UniProtKB:O95786 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24658140 UniProtKB:P00533 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25241761 UniProtKB:P01100 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25241761 UniProtKB:P04626 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25241761 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25241761 UniProtKB:Q05397 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q01804 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q8N9N8 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25609649 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26889034 UniProtKB:Q4VW77 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26966684 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26966684 UniProtKB:P52294 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26966684 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31980649 UniProtKB:P00533 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32953130 UniProtKB:P0DTC9 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32953130 UniProtKB:P23458 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34521819 UniProtKB:P0DTC9 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34521819 UniProtKB:P23458 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34950606 UniProtKB:P0DTC2 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34950606 UniProtKB:P23458 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35140242 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35140242 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:8156998 UniProtKB:P15260 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:8605877 UniProtKB:P52630 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:8662591 UniProtKB:P15260 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:8662591 UniProtKB:P40763 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9121453 UniProtKB:P17181 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9121453 UniProtKB:P48551 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9881977 UniProtKB:P03255-1 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:9881977 UniProtKB:P03255-2 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:8605877 UniProtKB:P42224 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 enables GO:0042802 identical protein binding molecular_function ECO:0000353 IPI PMID:9630226 UniProtKB:P42224 9606 Homo sapiens IntAct Signal transducer and activator of transcription 1-alpha/beta 20250830 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0005547 NAS PMID:24058793 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250808 UniProtKB P42224 STAT1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0005547 NAS PMID:24058793 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250808 UniProtKB P42224 STAT1 part_of GO:0090575 RNA polymerase II transcription regulator complex cellular_component ECO:0000353 IPI PMID:8662591 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250808 UniProtKB P42224 STAT1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000314 IDA PMID:24065129 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250731 UniProtKB P42224 STAT1 part_of GO:0070721 ISGF3 complex cellular_component ECO:0000353 IPI PMID:24065129 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250731 UniProtKB P42224 STAT1 part_of GO:0090575 RNA polymerase II transcription regulator complex cellular_component ECO:0005547 NAS PMID:24058793 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20250731 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00034574|UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0007584 response to nutrient biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0008015 blood circulation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0008284 positive regulation of cell population proliferation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0009410 response to xenobiotic stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0009612 response to mechanical stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 located_in GO:0030424 axon cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 located_in GO:0030425 dendrite cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 enables GO:0031730 CCR5 chemokine receptor binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0032869 cellular response to insulin stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0034097 response to cytokine biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0042542 response to hydrogen peroxide biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0043434 response to peptide hormone biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 enables GO:0043565 sequence-specific DNA binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0045429 positive regulation of nitric oxide biosynthetic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0048661 positive regulation of smooth muscle cell proliferation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0051591 response to cAMP biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 enables GO:0051721 protein phosphatase 2A binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 acts_upstream_of_or_within GO:0071345 cellular response to cytokine stimulus biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:A0A0G2JX93|ensembl:ENSRNOP00000070183 9606 Homo sapiens Ensembl Signal transducer and activator of transcription 1-alpha/beta 20250527 UniProtKB P42224 STAT1 involved_in GO:0097696 cell surface receptor signaling pathway via STAT biological_process ECO:0000314 IDA PMID:18035482 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20241216 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0005547 NAS PMID:9630226 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20241113 UniProtKB P42224 STAT1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0005547 NAS PMID:9630226 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20241113 UniProtKB P42224 STAT1 part_of GO:0090575 RNA polymerase II transcription regulator complex cellular_component ECO:0000353 IPI PMID:9630226 9606 Homo sapiens ComplexPortal Signal transducer and activator of transcription 1-alpha/beta 20241113 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Signal transducer and activator of transcription 1-alpha/beta 20241022 UniProtKB P42224 STAT1 located_in GO:0005730 nucleolus cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Signal transducer and activator of transcription 1-alpha/beta 20241022 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Signal transducer and activator of transcription 1-alpha/beta 20241022 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:32209697 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20240520 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:32209697 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20240520 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:32209697 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20240520 UniProtKB P42224 STAT1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000314 IDA PMID:32209697 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20240520 UniProtKB P42224 STAT1 involved_in GO:0038111 interleukin-7-mediated signaling pathway biological_process ECO:0000314 IDA PMID:29202461 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20240227 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9851142 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20231012 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20230615 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000305 IC PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20230117 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:21268089 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220819 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:18035482 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220819 UniProtKB P42224 STAT1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220819 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220708 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220708 UniProtKB P42224 STAT1 involved_in GO:0034341 response to type II interferon biological_process ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220708 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 involved_in GO:0035458 cellular response to interferon-beta biological_process ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 involved_in GO:0071346 cellular response to type II interferon biological_process ECO:0000314 IDA PMID:11972023 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220707 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220706 UniProtKB P42224 STAT1 involved_in GO:0006357 regulation of transcription by RNA polymerase II biological_process ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220706 UniProtKB P42224 STAT1 enables GO:0003700 DNA-binding transcription factor activity molecular_function ECO:0000314 IDA PMID:10973496 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220701 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:15322115 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220701 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000314 IDA PMID:22002246 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220701 UniProtKB P42224 STAT1 enables GO:0003700 DNA-binding transcription factor activity molecular_function ECO:0000314 IDA PMID:9535918 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220429 UniProtKB P42224 STAT1 is_active_in GO:0005634 nucleus cellular_component ECO:0000305 IC PMID:9535918 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220429 UniProtKB P42224 STAT1 involved_in GO:0038113 interleukin-9-mediated signaling pathway biological_process ECO:0000314 IDA PMID:9535918 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20220429 UniProtKB P42224 STAT1 enables GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function ECO:0000314 IDA PMID:22002246 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20210713 UniProtKB P42224 STAT1 enables GO:0001223 transcription coactivator binding molecular_function ECO:0000353 IPI PMID:22002246 UniProtKB:Q8TEK3-2 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20210713 UniProtKB P42224 STAT1 enables GO:0001222 transcription corepressor binding molecular_function ECO:0000353 IPI PMID:23386060 UniProtKB:Q9UIV1 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20210610 UniProtKB P42224 STAT1 involved_in GO:0070106 interleukin-27-mediated signaling pathway biological_process ECO:0000314 IDA PMID:32270034 9606 Homo sapiens ARUK-UCL Signal transducer and activator of transcription 1-alpha/beta 20210205 UniProtKB P42224 STAT1 enables GO:1990841 promoter-specific chromatin binding molecular_function ECO:0000314 IDA PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20200304 UniProtKB P42224 STAT1 located_in GO:0000785 chromatin cellular_component ECO:0005556 ISA GO_REF:0000113 tfclass:6.2.1 9606 Homo sapiens NTNU_SB Signal transducer and activator of transcription 1-alpha/beta 20190405 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0005556 ISA GO_REF:0000113 tfclass:6.2.1 9606 Homo sapiens NTNU_SB Signal transducer and activator of transcription 1-alpha/beta 20190405 UniProtKB P42224 STAT1 enables GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding molecular_function ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20180501 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8985981 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8985983 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-9865524 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985900 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985943 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985966 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985981 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985983 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985988 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9865511 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20180427 UniProtKB P42224 STAT1 enables GO:0045296 cadherin binding molecular_function ECO:0007005 HDA PMID:25468996 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20180329 UniProtKB P42224 STAT1 enables GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function ECO:0000314 IDA PMID:21268089 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20180228 UniProtKB P42224 STAT1 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function ECO:0000314 IDA PMID:21268089 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20180228 UniProtKB P42224 STAT1 involved_in GO:0002230 positive regulation of defense response to virus by host biological_process ECO:0000315 IMP PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 involved_in GO:0002230 positive regulation of defense response to virus by host biological_process ECO:0000316 IGI PMID:26479788 UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6|UniProtKB:Q93079 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 colocalizes_with GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:27796300 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0019899 enzyme binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q8IXQ6 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0019899 enzyme binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0035035 histone acetyltransferase binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q09472 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0042393 histone binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q93079 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0044389 ubiquitin-like protein ligase binding molecular_function ECO:0000353 IPI PMID:26479788 UniProtKB:Q8TDB6 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 involved_in GO:0045893 positive regulation of DNA-templated transcription biological_process ECO:0000315 IMP PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 involved_in GO:0045893 positive regulation of DNA-templated transcription biological_process ECO:0000316 IGI PMID:26479788 UniProtKB:Q8IXQ6|UniProtKB:Q8TDB6 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 involved_in GO:0060333 type II interferon-mediated signaling pathway biological_process ECO:0000315 IMP PMID:26479788 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170825 UniProtKB P42224 STAT1 enables GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding molecular_function ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28753426 UniProtKB:Q9BYW2 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 involved_in GO:0032727 positive regulation of interferon-alpha production biological_process ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 enables GO:0042803 protein homodimerization activity molecular_function ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 involved_in GO:0051607 defense response to virus biological_process ECO:0000314 IDA PMID:28753426 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170824 UniProtKB P42224 STAT1 enables GO:0003700 DNA-binding transcription factor activity molecular_function ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170510 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170510 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170510 UniProtKB P42224 STAT1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170510 UniProtKB P42224 STAT1 involved_in GO:0071346 cellular response to type II interferon biological_process ECO:0000314 IDA PMID:23386060 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170510 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8987218 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20170505 UniProtKB P42224 STAT1 involved_in GO:0045648 positive regulation of erythrocyte differentiation biological_process ECO:0000315 IMP PMID:28283061 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20170320 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112565 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112602 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1169406 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1433456 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1470009 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1678841 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1888198 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-380782 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6788571 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6788582 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6790041 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950441 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950453 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950485 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950518 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950522 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8983835 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8983841 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8983845 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8983983 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8983996 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8984014 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8984021 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8984023 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8985929 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8986985 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987007 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987033 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987080 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987097 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987150 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987218 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987230 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987255 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987266 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8987270 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9006870 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9006873 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9670412 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9670416 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9672159 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9672176 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9729454 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9835443 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20161202 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26889034 UniProtKB:Q4VW77 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20160812 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-1112587 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20160715 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-6788623 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20160715 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8950522 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20160715 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-8950733 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20160715 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-9021334 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20160715 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:15825084 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20160322 UniProtKB P42224 STAT1 located_in GO:0048471 perinuclear region of cytoplasm cellular_component ECO:0000314 IDA PMID:17275127 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20160322 UniProtKB P42224 STAT1 involved_in GO:0035456 response to interferon-beta biological_process ECO:0000315 IMP PMID:24882218 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20150709 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17275127 UniProtKB:P27958-PRO_0000037576 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20150424 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:17275127 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20150424 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15825084 UniProtKB:P52630 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20141112 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:15825084 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20141112 UniProtKB P42224 STAT1 involved_in GO:0046725 negative regulation by virus of viral protein levels in host cell biological_process ECO:0000315 IMP PMID:15825084 9606 Homo sapiens AgBase Signal transducer and activator of transcription 1-alpha/beta 20141112 UniProtKB P42224 STAT1 involved_in GO:0035458 cellular response to interferon-beta biological_process ECO:0000315 IMP PMID:18035482 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20140704 UniProtKB P42224 STAT1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000315 IMP PMID:18035482 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20140704 UniProtKB P42224 STAT1 involved_in GO:0060333 type II interferon-mediated signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P42225 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20130612 UniProtKB P42224 STAT1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:P42225 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20130612 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-1015699 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-1031713 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-1470012 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-873917 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-877281 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-909721 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-913529 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-9670426 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-997326 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112727 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1470010 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1470012 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-873917 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-873921 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-873922 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-873927 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909552 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909718 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909721 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909722 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909725 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-909726 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-913529 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9670417 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9670426 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9710959 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9710963 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-997309 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130523 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112538 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112587 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1112604 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6788622 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6788623 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-6788628 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950733 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8950782 9606 Homo sapiens Reactome Signal transducer and activator of transcription 1-alpha/beta 20130213 UniProtKB P42224 STAT1 located_in GO:0000785 chromatin cellular_component ECO:0000314 IDA PMID:18035482 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20121126 UniProtKB P42224 STAT1 enables GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function ECO:0000314 IDA PMID:18035482 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20121126 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12867595 UniProtKB:Q9P0J0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20120708 UniProtKB P42224 STAT1 involved_in GO:0000122 negative regulation of transcription by RNA polymerase II biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0001937 negative regulation of endothelial cell proliferation biological_process ECO:0000315 IMP PMID:16585190 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0002053 positive regulation of mesenchymal cell proliferation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0007259 cell surface receptor signaling pathway via JAK-STAT biological_process ECO:0000314 IDA PMID:22002246 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0016525 negative regulation of angiogenesis biological_process ECO:0000315 IMP PMID:16585190 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0042981 regulation of apoptotic process biological_process ECO:0000304 TAS PMID:12108949 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 NOT|involved_in GO:0043542 endothelial cell migration biological_process ECO:0000315 IMP PMID:16585190 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0061326 renal tubule development biological_process ECO:0000315 IMP PMID:20861313 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0072136 metanephric mesenchymal cell proliferation involved in metanephros development biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0072162 metanephric mesenchymal cell differentiation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 involved_in GO:0072308 negative regulation of metanephric nephron tubule epithelial cell differentiation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXK0 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111130 UniProtKB P42224 STAT1 enables GO:0003700 DNA-binding transcription factor activity molecular_function ECO:0000314 IDA PMID:10973496 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111129 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:10692450 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111129 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:10692450 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111129 UniProtKB P42224 STAT1 involved_in GO:0045893 positive regulation of DNA-templated transcription biological_process ECO:0000314 IDA PMID:10973496 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111129 UniProtKB P42224 STAT1 enables GO:0005164 tumor necrosis factor receptor binding molecular_function ECO:0000353 IPI PMID:10848577 UniProtKB:P19438 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 enables GO:0005164 tumor necrosis factor receptor binding molecular_function ECO:0000353 IPI PMID:10848577 UniProtKB:P20333 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:10848577 UniProtKB:Q15628 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:10973496 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:10973496 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 involved_in GO:0033209 tumor necrosis factor-mediated signaling pathway biological_process ECO:0000314 IDA PMID:10848577 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 involved_in GO:0043124 negative regulation of canonical NF-kappaB signal transduction biological_process ECO:0000315 IMP PMID:10848577 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111124 UniProtKB P42224 STAT1 enables GO:0003690 double-stranded DNA binding molecular_function ECO:0000314 IDA PMID:9630226 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111122 UniProtKB P42224 STAT1 enables GO:0042803 protein homodimerization activity molecular_function ECO:0000314 IDA PMID:9630226 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20111122 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:21268089 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20110323 UniProtKB P42224 STAT1 involved_in GO:0060333 type II interferon-mediated signaling pathway biological_process ECO:0000314 IDA PMID:21268089 9606 Homo sapiens BHF-UCL Signal transducer and activator of transcription 1-alpha/beta 20110323 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16531398 UniProtKB:Q96EY1-1 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20090406 UniProtKB P42224 STAT1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16306601 UniProtKB:P20749 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20070410 UniProtKB P42224 STAT1 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:16306601 9606 Homo sapiens UniProt Signal transducer and activator of transcription 1-alpha/beta 20070410