GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q92844 TANK located_in GO:0005737 cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20260601 UniProtKB Q92844 TANK involved_in GO:0043124 negative regulation of canonical NF-kappaB signal transduction biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR039669 9606 Homo sapiens InterPro TRAF family member-associated NF-kappa-B activator 20260601 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:12005438 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17500595 UniProtKB:P42858 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17568778 UniProtKB:Q14164 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17568778 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18307994 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20562859 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21212807 UniProtKB:P61956 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21212807 UniProtKB:P63165 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21212807 UniProtKB:Q14164 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21653829 UniProtKB:Q92574 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:O96018 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:P17362 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:Q14164 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:P53350 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q13077 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24008843 UniProtKB:P03495 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q05519 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q13625-3 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q96MT8 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25852190 UniProtKB:Q14164 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26638075 UniProtKB:Q96MT8 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q13077 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29251827 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q9UHD2 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P53350 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q12933 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q13077 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q14164 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34084167 UniProtKB:Q13114 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct TRAF family member-associated NF-kappa-B activator 20260530 UniProtKB Q92844 TANK located_in GO:0005730 nucleolus cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA TRAF family member-associated NF-kappa-B activator 20251115 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA TRAF family member-associated NF-kappa-B activator 20251115 UniProtKB Q92844 TANK involved_in GO:0051607 defense response to virus biological_process ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal TRAF family member-associated NF-kappa-B activator 20251007 UniProtKB Q92844 TANK involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal TRAF family member-associated NF-kappa-B activator 20251007 UniProtKB Q92844 TANK part_of GO:1902554 serine/threonine protein kinase complex cellular_component ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal TRAF family member-associated NF-kappa-B activator 20251007 UniProtKB Q92844 TANK is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:21931631 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20220701 UniProtKB Q92844 TANK involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000314 IDA PMID:21931631 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20220701 UniProtKB Q92844 TANK enables GO:0060090 molecular adaptor activity molecular_function ECO:0000314 IDA PMID:21931631 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20220701 UniProtKB Q92844 TANK contributes_to GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:0006974 DNA damage response biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK enables GO:0035800 deubiquitinase activator activity molecular_function ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:0043124 negative regulation of canonical NF-kappaB signal transduction biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:0071347 cellular response to interleukin-1 biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:0071356 cellular response to tumor necrosis factor biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:0071479 cellular response to ionizing radiation biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:1903003 positive regulation of protein deubiquitination biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK involved_in GO:2000158 positive regulation of ubiquitin-specific protease activity biological_process ECO:0000315 IMP PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160628 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25861989 UniProtKB:Q14694|UniProtKB:Q5D1E8|UniProtKB:Q9Y4K3|UniProtKB:Q9Y6K9 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160624 UniProtKB Q92844 TANK part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:25861989 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20160624 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-166245 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-166271 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-5362500 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013978 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013979 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013990 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823904 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823906 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823910 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823932 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823934 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823939 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9824882 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828196 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828200 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828204 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828205 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828209 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9830706 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9830710 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20140416 UniProtKB Q92844 TANK enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000353 IPI PMID:11279055 UniProtKB:O94972 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20120518 UniProtKB Q92844 TANK enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21784977 UniProtKB:P26651 9606 Homo sapiens UniProt TRAF family member-associated NF-kappa-B activator 20111209 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-5362486 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013985 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933525 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933527 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933537 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933538 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705145 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705323 9606 Homo sapiens Reactome TRAF family member-associated NF-kappa-B activator 20100815 UniProtKB Q92844 TANK involved_in GO:0007165 signal transduction biological_process ECO:0000304 TAS PMID:8710854 9606 Homo sapiens PINC TRAF family member-associated NF-kappa-B activator 20030904