GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9UHD2 TBK1 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0024222|FB:FBgn0086657|MGI:MGI:1338071|MGI:MGI:99484|PANTHER:PTN001491808|RGD:1306661|RGD:621375|UniProtKB:O14920|UniProtKB:O15111|UniProtKB:Q14164|UniProtKB:Q9UHD2 9606 Homo sapiens GO_Central Serine/threonine-protein kinase TBK1 20251220 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000318 IBA GO_REF:0000033 FB:FBgn0024222|FB:FBgn0086657|MGI:MGI:1338071|MGI:MGI:1929612|MGI:MGI:1929658|MGI:MGI:99484|PANTHER:PTN001491808|RGD:621375|UniProtKB:O14920|UniProtKB:O15111|UniProtKB:Q14164|UniProtKB:Q9UHD2 9606 Homo sapiens GO_Central Serine/threonine-protein kinase TBK1 20241120 UniProtKB Q9UHD2 TBK1 involved_in GO:0002218 activation of innate immune response biological_process ECO:0000318 IBA GO_REF:0000033 FB:FBgn0086657|MGI:MGI:1929658|PANTHER:PTN000540338|UniProtKB:Q9UHD2 9606 Homo sapiens GO_Central Serine/threonine-protein kinase TBK1 20240321 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:1929658|PANTHER:PTN000540338|UniProtKB:Q14164|UniProtKB:Q9UHD2 9606 Homo sapiens GO_Central Serine/threonine-protein kinase TBK1 20240321 UniProtKB Q9UHD2 TBK1 involved_in GO:0002218 activation of innate immune response biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00034386 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 enables GO:0004672 protein kinase activity molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000719 9606 Homo sapiens InterPro Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00027016|UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316|EC:2.7.11.1 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 enables GO:0005524 ATP binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR000719|InterPro:IPR017441 9606 Homo sapiens InterPro Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 located_in GO:0005737 cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0006952 defense response biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026315 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0016239 positive regulation of macroautophagy biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00086948 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0032008 positive regulation of TOR signaling biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00092062 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0032728 positive regulation of interferon-beta production biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00085789 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0043123 positive regulation of canonical NF-kappaB signal transduction biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00026690 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 involved_in GO:0051707 response to other organism biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00029118 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0007322 IEA GO_REF:0000116 RHEA:17989 9606 Homo sapiens RHEA Serine/threonine-protein kinase TBK1 20260601 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:A7MCY6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:P08238 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q9H6S1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14743216 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15841462 UniProtKB:P27958-PRO_0000037573 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15841462 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15841462 UniProtKB:Q8IUC6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16306936 UniProtKB:Q60803 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17568778 UniProtKB:A7MCY6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17568778 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17599067 UniProtKB:Q14164 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17599067 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17599067 UniProtKB:Q92985 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18307994 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18307994 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18583960 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18583960 UniProtKB:Q62167 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18724357 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19153231 UniProtKB:Q05127 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19153231 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19380580 UniProtKB:P59596 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19416887 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19416887 UniProtKB:Q8IUC6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19433799 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20098747 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20562859 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:A7MCY6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:P40222 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q13137 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q14164 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q6DT37 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q7Z3C6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q7Z434 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q86YT6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q8BHN1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q8IUC6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q96AX9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q9H6S1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q9NVV4 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21903422 UniProtKB:Q9UKV8 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:A7MCY6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21931555 UniProtKB:Q9H6S1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:O75558 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21988832 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22000020 UniProtKB:P42226 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22939624 UniProtKB:P08238 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23096996 UniProtKB:P27958-PRO_0000037572 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23414517 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:23542348 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24509444 UniProtKB:P59596 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24622840 UniProtKB:Q86WV6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24643253 UniProtKB:Q7Z434 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24696485 UniProtKB:O41932 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24807708 UniProtKB:O14730 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24807708 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25803835 UniProtKB:Q14653 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25803835 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27086836 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27094905 UniProtKB:Q60803 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27135603 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27135603 UniProtKB:Q13114 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27135603 UniProtKB:Q9Y6W8 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:O75558 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:P40222 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q13137 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29251827 UniProtKB:O95801 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29251827 UniProtKB:Q14164 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29251827 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:29251827 UniProtKB:Q9H6S1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30561431 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32353859 UniProtKB:P0DTD1-PRO_0000449630 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:A7MCY6 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:P40222 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q13137 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q6DT37 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:Q9H6S1 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32979938 UniProtKB:P0DTD1-PRO_0000449630 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33060197 UniProtKB:P0DTD1-PRO_0000449630 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33372174 UniProtKB:P0DTC5 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33372174 UniProtKB:Q13114 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33372174 UniProtKB:Q7Z434 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33707416 UniProtKB:P0DTD1-PRO_0000449630 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O75558 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P40222 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q12933 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q13137 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q92844 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34084167 UniProtKB:P0DTC5 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34084167 UniProtKB:P59596 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34084167 UniProtKB:Q13114 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34166398 UniProtKB:P0DTD1-PRO_0000449630 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34524948 UniProtKB:Q13137 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34524948 UniProtKB:Q96CV9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:37219487 UniProtKB:Q9GZQ8 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:37219487 UniProtKB:Q9H492 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:O75558 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:Q9Y6K9 9606 Homo sapiens IntAct Serine/threonine-protein kinase TBK1 20260530 UniProtKB Q9UHD2 TBK1 enables GO:0003676 nucleic acid binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 involved_in GO:0010629 negative regulation of gene expression biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 enables GO:0019903 protein phosphatase binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 enables GO:0042802 identical protein binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 involved_in GO:0060340 positive regulation of type I interferon-mediated signaling pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 involved_in GO:1904417 positive regulation of xenophagy biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 involved_in GO:1904515 positive regulation of TORC2 signaling biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9WUN2|ensembl:ENSMUSP00000020316 9606 Homo sapiens Ensembl Serine/threonine-protein kinase TBK1 20260529 UniProtKB Q9UHD2 TBK1 involved_in GO:0016236 macroautophagy biological_process ECO:0000304 TAS Reactome:R-HSA-5205685 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260316 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000304 TAS Reactome:R-HSA-1834941 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260316 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000304 TAS Reactome:R-HSA-3270619 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260316 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000269 EXP PMID:27035970 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260222 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-2396007 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260222 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-3249371 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260222 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-933525 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20260222 UniProtKB Q9UHD2 TBK1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Serine/threonine-protein kinase TBK1 20251115 UniProtKB Q9UHD2 TBK1 located_in GO:0005737 cytoplasm cellular_component ECO:0000269 EXP PMID:15485837 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 located_in GO:0005737 cytoplasm cellular_component ECO:0000269 EXP PMID:32298923 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:10783893 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:15367631 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:18583960 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:21138416 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:21270402 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:21464307 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:21617041 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:29150432 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:31530866 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000269 EXP PMID:31709703 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20251027 UniProtKB Q9UHD2 TBK1 involved_in GO:0051607 defense response to virus biological_process ECO:0005547 NAS PMID:17142768 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 involved_in GO:0051607 defense response to virus biological_process ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 involved_in GO:0051607 defense response to virus biological_process ECO:0005547 NAS PMID:24622840 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0005547 NAS PMID:17142768 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 involved_in GO:0060337 type I interferon-mediated signaling pathway biological_process ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 part_of GO:1902554 serine/threonine protein kinase complex cellular_component ECO:0005547 NAS PMID:17142768 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 part_of GO:1902554 serine/threonine protein kinase complex cellular_component ECO:0005547 NAS PMID:21931631 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 part_of GO:1902554 serine/threonine protein kinase complex cellular_component ECO:0005547 NAS PMID:24622840 9606 Homo sapiens ComplexPortal Serine/threonine-protein kinase TBK1 20251007 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18818105 UniProtKB:Q7Z434 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20250216 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18818105 UniProtKB:Q86WV6 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20250216 UniProtKB Q9UHD2 TBK1 involved_in GO:0002753 cytoplasmic pattern recognition receptor signaling pathway biological_process ECO:0000314 IDA PMID:29441066 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20250121 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20250121 UniProtKB Q9UHD2 TBK1 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20250121 UniProtKB Q9UHD2 TBK1 enables GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding molecular_function ECO:0000353 IPI PMID:22412986 UniProtKB:Q13568 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20241217 UniProtKB Q9UHD2 TBK1 enables GO:0106310 protein serine kinase activity molecular_function ECO:0000314 IDA PMID:22412986 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20241217 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20241107 UniProtKB Q9UHD2 TBK1 involved_in GO:0140896 cGAS/STING signaling pathway biological_process ECO:0000304 TAS PMID:37403426 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20241107 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000250 ISS GO_REF:0000024 MGI:MGI:1929658 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240924 UniProtKB Q9UHD2 TBK1 involved_in GO:1904515 positive regulation of TORC2 signaling biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9WUN2 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240923 UniProtKB Q9UHD2 TBK1 is_active_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:21813773 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240910 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240910 UniProtKB Q9UHD2 TBK1 involved_in GO:0061470 T follicular helper cell differentiation biological_process ECO:0000314 IDA PMID:27135603 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240822 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32209697 UniProtKB:O14920 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240520 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240206 UniProtKB Q9UHD2 TBK1 involved_in GO:0140374 antiviral innate immune response biological_process ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20240206 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20231122 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000304 TAS PMID:37403426 9606 Homo sapiens FlyBase Serine/threonine-protein kinase TBK1 20231116 UniProtKB Q9UHD2 TBK1 is_active_in GO:0005829 cytosol cellular_component ECO:0000304 TAS PMID:37403426 9606 Homo sapiens FlyBase Serine/threonine-protein kinase TBK1 20231116 UniProtKB Q9UHD2 TBK1 involved_in GO:0140896 cGAS/STING signaling pathway biological_process ECO:0000304 TAS PMID:37403426 9606 Homo sapiens FlyBase Serine/threonine-protein kinase TBK1 20231116 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:22394562 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230824 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000314 IDA PMID:22394562 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230824 UniProtKB Q9UHD2 TBK1 involved_in GO:0140374 antiviral innate immune response biological_process ECO:0000314 IDA PMID:22394562 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230824 UniProtKB Q9UHD2 TBK1 involved_in GO:0002218 activation of innate immune response biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230810 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230627 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230608 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:29150432 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230606 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:31530866 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230606 UniProtKB Q9UHD2 TBK1 involved_in GO:1904262 negative regulation of TORC1 signaling biological_process ECO:0000314 IDA PMID:31530866 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230606 UniProtKB Q9UHD2 TBK1 involved_in GO:1904263 positive regulation of TORC1 signaling biological_process ECO:0000314 IDA PMID:29150432 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230606 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230322 UniProtKB Q9UHD2 TBK1 involved_in GO:0034142 toll-like receptor 4 signaling pathway biological_process ECO:0000314 IDA PMID:28747347 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230322 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230208 UniProtKB Q9UHD2 TBK1 involved_in GO:0140374 antiviral innate immune response biological_process ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230208 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20230117 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:22394562 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20221025 UniProtKB Q9UHD2 TBK1 involved_in GO:0140374 antiviral innate immune response biological_process ECO:0000314 IDA PMID:22394562 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20221025 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20221012 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20221012 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:22921120 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220929 UniProtKB Q9UHD2 TBK1 involved_in GO:0010508 positive regulation of autophagy biological_process ECO:0000314 IDA PMID:28871090 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220928 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:29441066 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220810 UniProtKB Q9UHD2 TBK1 acts_upstream_of_or_within GO:0032728 positive regulation of interferon-beta production biological_process ECO:0000314 IDA PMID:31390091 9606 Homo sapiens MGI Serine/threonine-protein kinase TBK1 20220720 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:29441066 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220713 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:29441066 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220707 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000314 IDA PMID:29441066 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220707 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220701 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:14703513 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20220624 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:31709703 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20210916 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34084167 UniProtKB:P0DTC5 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20210817 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823904 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20210507 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828200 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20210507 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20628368 UniProtKB:O94826|UniProtKB:P07900|UniProtKB:Q14653 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20201103 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:30354798 UniProtKB:Q5SW79 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20201019 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:31662325 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20200918 UniProtKB Q9UHD2 TBK1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:29251827 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190715 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28011935 UniProtKB:Q14166 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190625 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28011935 UniProtKB:Q7Z434 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190625 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190321 UniProtKB Q9UHD2 TBK1 involved_in GO:0018105 peptidyl-serine phosphorylation biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190321 UniProtKB Q9UHD2 TBK1 involved_in GO:0018107 peptidyl-threonine phosphorylation biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190321 UniProtKB Q9UHD2 TBK1 involved_in GO:0032479 regulation of type I interferon production biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190321 UniProtKB Q9UHD2 TBK1 involved_in GO:0045087 innate immune response biological_process ECO:0000314 IDA PMID:25636800 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20190321 UniProtKB Q9UHD2 TBK1 enables GO:0019903 protein phosphatase binding molecular_function ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9WUN2 9606 Homo sapiens ARUK-UCL Serine/threonine-protein kinase TBK1 20180801 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9008684 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20170613 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:27103069 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20170404 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:27103069 UniProtKB:Q8TEV9 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20170404 UniProtKB Q9UHD2 TBK1 involved_in GO:0006468 protein phosphorylation biological_process ECO:0000314 IDA PMID:27103069 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20170404 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24560620 UniProtKB:Q7RTR2 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20170309 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:27103069 9606 Homo sapiens HGNC Serine/threonine-protein kinase TBK1 20170217 UniProtKB Q9UHD2 TBK1 involved_in GO:0016239 positive regulation of macroautophagy biological_process ECO:0000314 IDA PMID:27103069 9606 Homo sapiens HGNC Serine/threonine-protein kinase TBK1 20170217 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:25636800 9606 Homo sapiens CACAO Serine/threonine-protein kinase TBK1 20151001 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25736436 UniProtKB:Q8IUC6 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20150912 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000314 IDA PMID:25803835 9606 Homo sapiens ParkinsonsUK-UCL Serine/threonine-protein kinase TBK1 20150623 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25803835 UniProtKB:Q96CV9 9606 Homo sapiens ParkinsonsUK-UCL Serine/threonine-protein kinase TBK1 20150623 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:24056301 UniProtKB:Q96KP1 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20141204 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-3249386 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130517 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8948709 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130517 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1606327 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-166245 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-166271 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-2396002 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-2396007 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-3249371 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-3249390 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-3249392 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-8948703 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013978 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9013979 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-918229 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-918232 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933525 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933538 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9679819 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705320 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705323 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9817397 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9817411 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823906 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9824892 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9824894 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9824897 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828205 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9840807 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20130213 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19416887 UniProtKB:Q86WV6 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20120730 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21813773 UniProtKB:O14879 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20120726 UniProtKB Q9UHD2 TBK1 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:21813773 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20120726 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18636086 UniProtKB:Q9NQC7 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20120708 UniProtKB Q9UHD2 TBK1 enables GO:0004674 protein serine/threonine kinase activity molecular_function ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0006954 inflammatory response biological_process ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0007249 canonical NF-kappaB signal transduction biological_process ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0009615 response to virus biological_process ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0032481 positive regulation of type I interferon production biological_process ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0045087 innate immune response biological_process ECO:0000304 TAS PMID:21042276 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110912 UniProtKB Q9UHD2 TBK1 involved_in GO:0032727 positive regulation of interferon-alpha production biological_process ECO:0000314 IDA PMID:16127453 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20110310 UniProtKB Q9UHD2 TBK1 involved_in GO:0032728 positive regulation of interferon-beta production biological_process ECO:0000314 IDA PMID:16127453 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20110310 UniProtKB Q9UHD2 TBK1 involved_in GO:0045944 positive regulation of transcription by RNA polymerase II biological_process ECO:0000314 IDA PMID:16127453 9606 Homo sapiens BHF-UCL Serine/threonine-protein kinase TBK1 20110310 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19419966 UniProtKB:P12931 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20110307 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20174559 UniProtKB:Q96CV9 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20100810 UniProtKB Q9UHD2 TBK1 enables GO:0051219 phosphoprotein binding molecular_function ECO:0000353 IPI PMID:14530355 UniProtKB:Q8IUC6 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20091222 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-1834939 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-3249378 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-918225 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-933527 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-937337 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705010 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705082 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705137 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9705145 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9709831 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9709852 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9710988 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9754827 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823910 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9823934 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9824888 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828196 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9828209 9606 Homo sapiens Reactome Serine/threonine-protein kinase TBK1 20091216 UniProtKB Q9UHD2 TBK1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16281057 UniProtKB:O95786 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20090907 UniProtKB Q9UHD2 TBK1 involved_in GO:0043123 positive regulation of canonical NF-kappaB signal transduction biological_process ECO:0000270 IEP PMID:12761501 9606 Homo sapiens UniProt Serine/threonine-protein kinase TBK1 20061120 UniProtKB Q9UHD2 TBK1 enables GO:0004672 protein kinase activity molecular_function ECO:0000303 NAS PMID:10581243 9606 Homo sapiens PINC Serine/threonine-protein kinase TBK1 20040811 UniProtKB Q9UHD2 TBK1 involved_in GO:0007249 canonical NF-kappaB signal transduction biological_process ECO:0000304 TAS PMID:10581243 9606 Homo sapiens PINC Serine/threonine-protein kinase TBK1 20030904