GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q15650 TRIP4 enables GO:0003713 transcription coactivator activity molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008344380|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20250702 UniProtKB Q15650 TRIP4 involved_in GO:0030520 estrogen receptor signaling pathway biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000311352|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20250702 UniProtKB Q15650 TRIP4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008344380|SGD:S000001731|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20250702 UniProtKB Q15650 TRIP4 part_of GO:0180022 RQC-trigger complex cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008344380|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20250702 UniProtKB Q15650 TRIP4 is_active_in GO:0005634 nucleus cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008344380|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20250412 UniProtKB Q15650 TRIP4 involved_in GO:0045893 positive regulation of DNA-templated transcription biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008344380|UniProtKB:Q15650 9606 Homo sapiens GO_Central Activating signal cointegrator 1 20170228 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000501 IEA GO_REF:0000120 InterPro:IPR009349|UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 located_in GO:0005813 centrosome cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0048 9606 Homo sapiens UniProt Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 located_in GO:0005829 cytosol cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0091 9606 Homo sapiens UniProt Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 enables GO:0008270 zinc ion binding molecular_function ECO:0000256 IEA GO_REF:0000002 InterPro:IPR009349 9606 Homo sapiens InterPro Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR009349 9606 Homo sapiens InterPro Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 part_of GO:0180022 RQC-trigger complex cellular_component ECO:0000256 IEA GO_REF:0000002 InterPro:IPR009349 9606 Homo sapiens InterPro Activating signal cointegrator 1 20260601 UniProtKB Q15650 TRIP4 involved_in GO:0045661 regulation of myoblast differentiation biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:Q9QXN3|ensembl:ENSMUSP00000113949 9606 Homo sapiens Ensembl Activating signal cointegrator 1 20260529 UniProtKB Q15650 TRIP4 located_in GO:0005654 nucleoplasm cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Activating signal cointegrator 1 20251115 UniProtKB Q15650 TRIP4 located_in GO:0016604 nuclear body cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Activating signal cointegrator 1 20251115 UniProtKB Q15650 TRIP4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948291 9606 Homo sapiens Reactome Activating signal cointegrator 1 20250519 UniProtKB Q15650 TRIP4 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948300 9606 Homo sapiens Reactome Activating signal cointegrator 1 20250519 UniProtKB Q15650 TRIP4 involved_in GO:0032790 ribosome disassembly biological_process ECO:0005547 NAS PMID:32099016 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 20240823 UniProtKB Q15650 TRIP4 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:32099016 9606 Homo sapiens ComplexPortal Activating signal cointegrator 1 20240823 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000269 EXP PMID:20873783 9606 Homo sapiens UniProt Activating signal cointegrator 1 20230412 UniProtKB Q15650 TRIP4 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt Activating signal cointegrator 1 20230215 UniProtKB Q15650 TRIP4 involved_in GO:0032790 ribosome disassembly biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 20230215 UniProtKB Q15650 TRIP4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt Activating signal cointegrator 1 20230215 UniProtKB Q15650 TRIP4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt Activating signal cointegrator 1 20230215 UniProtKB Q15650 TRIP4 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt Activating signal cointegrator 1 20210527 UniProtKB Q15650 TRIP4 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt Activating signal cointegrator 1 20210527 UniProtKB Q15650 TRIP4 colocalizes_with GO:0005813 centrosome cellular_component ECO:0000314 IDA PMID:20873783 9606 Homo sapiens UniProt Activating signal cointegrator 1 20170629 UniProtKB Q15650 TRIP4 enables GO:0019901 protein kinase binding molecular_function ECO:0000353 IPI PMID:20873783 UniProtKB:Q9HC98 9606 Homo sapiens UniProt Activating signal cointegrator 1 20170629 UniProtKB Q15650 TRIP4 part_of GO:0032991 protein-containing complex cellular_component ECO:0000314 IDA PMID:20873783 9606 Homo sapiens UniProt Activating signal cointegrator 1 20170629 UniProtKB Q15650 TRIP4 involved_in GO:0045661 regulation of myoblast differentiation biological_process ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9QXN3 9606 Homo sapiens UniProt Activating signal cointegrator 1 20161109 UniProtKB Q15650 TRIP4 part_of GO:0180022 RQC-trigger complex cellular_component ECO:0000314 IDA PMID:12077347 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160822 UniProtKB Q15650 TRIP4 involved_in GO:0006355 regulation of DNA-templated transcription biological_process ECO:0000314 IDA PMID:12077347 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160527 UniProtKB Q15650 TRIP4 involved_in GO:0006355 regulation of DNA-templated transcription biological_process ECO:0000315 IMP PMID:26924529 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160527 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:12077347 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160526 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:26924529 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160525 UniProtKB Q15650 TRIP4 located_in GO:0031594 neuromuscular junction cellular_component ECO:0000315 IMP PMID:26924529 9606 Homo sapiens UniProt Activating signal cointegrator 1 20160524 UniProtKB Q15650 TRIP4 involved_in GO:0030520 estrogen receptor signaling pathway biological_process ECO:0000314 IDA PMID:25219498 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141210 UniProtKB Q15650 TRIP4 enables GO:0003713 transcription coactivator activity molecular_function ECO:0000315 IMP PMID:25219498 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141208 UniProtKB Q15650 TRIP4 involved_in GO:0045893 positive regulation of DNA-templated transcription biological_process ECO:0000315 IMP PMID:25219498 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141208 UniProtKB Q15650 TRIP4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:Q15788 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141120 UniProtKB Q15650 TRIP4 enables GO:0030331 nuclear estrogen receptor binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:P03372 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141120 UniProtKB Q15650 TRIP4 enables GO:0035035 histone acetyltransferase binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:Q09472 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141120 UniProtKB Q15650 TRIP4 enables GO:0002020 protease binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:Q9NUQ7 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141119 UniProtKB Q15650 TRIP4 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:Q96HY6 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141119 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:25219498 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141119 UniProtKB Q15650 TRIP4 enables GO:0044389 ubiquitin-like protein ligase binding molecular_function ECO:0000353 IPI PMID:25219498 UniProtKB:O94874 9606 Homo sapiens UniProt Activating signal cointegrator 1 20141119 UniProtKB Q15650 TRIP4 located_in GO:0005634 nucleus cellular_component ECO:0000314 IDA PMID:10454579 9606 Homo sapiens UniProt Activating signal cointegrator 1 20021105 UniProtKB Q15650 TRIP4 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:10454579 9606 Homo sapiens UniProt Activating signal cointegrator 1 20021105 UniProtKB Q15650 TRIP4 enables GO:0016922 nuclear receptor binding molecular_function ECO:0000314 IDA PMID:10454579 9606 Homo sapiens UniProt Activating signal cointegrator 1 20021105