GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q92890 UFD1 involved_in GO:0036503 ERAD pathway biological_process ECO:0000318 IBA GO_REF:0000033 MGI:MGI:109353|PANTHER:PTN000285104|RGD:619822|SGD:S000003280|UniProtKB:Q92890|WB:WBGene00006733 9606 Homo sapiens GO_Central Ubiquitin recognition factor in ER-associated degradation protein 1 20250903 UniProtKB Q92890 UFD1 enables GO:0031593 polyubiquitin modification-dependent protein binding molecular_function ECO:0000318 IBA GO_REF:0000033 MGI:MGI:109353|PANTHER:PTN000285104|SGD:S000003280 9606 Homo sapiens GO_Central Ubiquitin recognition factor in ER-associated degradation protein 1 20190815 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000318 IBA GO_REF:0000033 MGI:MGI:109353|PANTHER:PTN000285104|RGD:619822|SGD:S000003280|UniProtKB:Q92890|WB:WBGene00006733 9606 Homo sapiens GO_Central Ubiquitin recognition factor in ER-associated degradation protein 1 20190815 UniProtKB Q92890 UFD1 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260601 UniProtKB Q92890 UFD1 located_in GO:0005829 cytosol cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0091 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260601 UniProtKB Q92890 UFD1 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR004854 9606 Homo sapiens InterPro Ubiquitin recognition factor in ER-associated degradation protein 1 20260601 UniProtKB Q92890 UFD1 involved_in GO:0030970 retrograde protein transport, ER to cytosol biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00087984 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260601 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18775313 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18775313 UniProtKB:Q8TAT6 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20414249 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:20414249 UniProtKB:Q8TAT6 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21645854 UniProtKB:Q8TAT6 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25959826 UniProtKB:P42858 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26712280 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q8TAT6 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P42858 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q8TAT6 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:37776851 UniProtKB:P55072 9606 Homo sapiens IntAct Ubiquitin recognition factor in ER-associated degradation protein 1 20260530 UniProtKB Q92890 UFD1 located_in GO:0005737 cytoplasm cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70362|ensembl:ENSMUSP00000005394 9606 Homo sapiens Ensembl Ubiquitin recognition factor in ER-associated degradation protein 1 20260529 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00090874|UniProtKB:P70362|ensembl:ENSMUSP00000005394 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260529 UniProtKB Q92890 UFD1 enables GO:0036435 K48-linked polyubiquitin modification-dependent protein binding molecular_function ECO:0000265 IEA GO_REF:0000107 UniProtKB:P70362|ensembl:ENSMUSP00000005394 9606 Homo sapiens Ensembl Ubiquitin recognition factor in ER-associated degradation protein 1 20260529 UniProtKB Q92890 UFD1 part_of GO:0036501 UFD1-NPL4 complex cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00091676|UniProtKB:P70362|ensembl:ENSMUSP00000005394 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260529 UniProtKB Q92890 UFD1 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0007322 IEA GO_REF:0000041 UniPathway:UPA00144 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20260227 UniProtKB Q92890 UFD1 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:33712450 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:18775313 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:20414249 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000353 IPI PMID:39329031 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 involved_in GO:0036503 ERAD pathway biological_process ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 involved_in GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:39329031 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:28819009 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:33712450 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 part_of GO:1904949 ATPase complex cellular_component ECO:0005547 NAS PMID:39329031 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20251229 UniProtKB Q92890 UFD1 located_in GO:0005634 nucleus cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9ES53 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20251027 UniProtKB Q92890 UFD1 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20240823 UniProtKB Q92890 UFD1 part_of GO:1990112 RQC complex cellular_component ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20240823 UniProtKB Q92890 UFD1 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0005547 NAS PMID:35452614 9606 Homo sapiens ComplexPortal Ubiquitin recognition factor in ER-associated degradation protein 1 20240823 UniProtKB Q92890 UFD1 involved_in GO:0036503 ERAD pathway biological_process ECO:0000315 IMP PMID:24089527 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20231121 UniProtKB Q92890 UFD1 involved_in GO:0071218 cellular response to misfolded protein biological_process ECO:0000315 IMP PMID:24089527 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20231121 UniProtKB Q92890 UFD1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9755507 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20191126 UniProtKB Q92890 UFD1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9758088 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20191126 UniProtKB Q92890 UFD1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9758090 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20191126 UniProtKB Q92890 UFD1 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948427 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20191126 UniProtKB Q92890 UFD1 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20170110 UniProtKB Q92890 UFD1 involved_in GO:0032480 negative regulation of type I interferon production biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20170110 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000314 IDA PMID:26471729 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20170110 UniProtKB Q92890 UFD1 involved_in GO:0039536 negative regulation of RIG-I signaling pathway biological_process ECO:0000315 IMP PMID:26471729 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20170110 UniProtKB Q92890 UFD1 part_of GO:0036501 UFD1-NPL4 complex cellular_component ECO:0000353 IPI PMID:11574150 UniProtKB:Q8TAT6 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20150521 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11574150 UniProtKB:Q8TAT6 9606 Homo sapiens HGNC-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20150421 UniProtKB Q92890 UFD1 involved_in GO:0030970 retrograde protein transport, ER to cytosol biological_process ECO:0000315 IMP PMID:25660456 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20150421 UniProtKB Q92890 UFD1 part_of GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex cellular_component ECO:0000250 ISS GO_REF:0000024 UniProtKB:Q9ES53 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin recognition factor in ER-associated degradation protein 1 20150421 UniProtKB Q92890 UFD1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5654985 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20141204 UniProtKB Q92890 UFD1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-5654989 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20141204 UniProtKB Q92890 UFD1 located_in GO:0005654 nucleoplasm cellular_component ECO:0000304 TAS Reactome:R-HSA-6781922 9606 Homo sapiens Reactome Ubiquitin recognition factor in ER-associated degradation protein 1 20141204 UniProtKB Q92890 UFD1 located_in GO:0005634 nucleus cellular_component ECO:0007005 HDA PMID:21630459 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20140320 UniProtKB Q92890 UFD1 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:17681147 UniProtKB:Q9UKV5 9606 Homo sapiens UniProt Ubiquitin recognition factor in ER-associated degradation protein 1 20080102 UniProtKB Q92890 UFD1 involved_in GO:0001501 skeletal system development biological_process ECO:0000304 TAS PMID:10024240 9606 Homo sapiens PINC Ubiquitin recognition factor in ER-associated degradation protein 1 20030904 UniProtKB Q92890 UFD1 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000304 TAS PMID:9063746 9606 Homo sapiens PINC Ubiquitin recognition factor in ER-associated degradation protein 1 20030904 UniProtKB Q92890 UFD1 involved_in GO:0006511 ubiquitin-dependent protein catabolic process biological_process ECO:0000304 TAS PMID:9063746 9606 Homo sapiens PINC Ubiquitin recognition factor in ER-associated degradation protein 1 20030904