GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9UHP3 USP25 enables GO:0032183 SUMO binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN008600562|UniProtKB:Q9UHP3 9606 Homo sapiens GO_Central Ubiquitin carboxyl-terminal hydrolase 25 20170613 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000501 IEA GO_REF:0000120 InterPro:IPR001394|InterPro:IPR018200|EC:3.4.19.12 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20260601 UniProtKB Q9UHP3 USP25 located_in GO:0005634 nucleus cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0191 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20260601 UniProtKB Q9UHP3 USP25 located_in GO:0005737 cytoplasm cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0086 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20260601 UniProtKB Q9UHP3 USP25 involved_in GO:0016579 protein deubiquitination biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR001394 9606 Homo sapiens InterPro Ubiquitin carboxyl-terminal hydrolase 25 20260601 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:P43405 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:22153077 UniProtKB:Q9H2K2 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:O15481 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:P43405 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:P54725 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:P61956 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q9BUY5 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:P31150 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:P54727 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:P54725 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P43405 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P54725 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P54727 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:P61956 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q3MIT2 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9BTV4 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32296183 UniProtKB:Q9UJV3-2 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32707033 UniProtKB:P43405 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P17612 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P37173 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P54725 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33060197 UniProtKB:P0DTD1-PRO_0000449633 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P31150 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:P54727 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:34232536 UniProtKB:P0DTD1-PRO_0000449633 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35914814 UniProtKB:P31150 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35914814 UniProtKB:P54727 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35914814 UniProtKB:Q9H2K2 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36217029 UniProtKB:P0DTD1-PRO_0000449633 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P54725 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:40205054 UniProtKB:P54727 9606 Homo sapiens IntAct Ubiquitin carboxyl-terminal hydrolase 25 20260530 UniProtKB Q9UHP3 USP25 involved_in GO:0006955 immune response biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0006979 response to oxidative stress biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0016071 mRNA metabolic process biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0031098 stress-activated protein kinase signaling cascade biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0065003 protein-containing complex assembly biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0097400 interleukin-17-mediated signaling pathway biological_process ECO:0000265 IEA GO_REF:0000107 UniProtKB:P57080|ensembl:ENSMUSP00000023580 9606 Homo sapiens Ensembl Ubiquitin carboxyl-terminal hydrolase 25 20260529 UniProtKB Q9UHP3 USP25 involved_in GO:0016579 protein deubiquitination biological_process ECO:0000304 TAS Reactome:R-HSA-5688426 9606 Homo sapiens Reactome Ubiquitin carboxyl-terminal hydrolase 25 20260316 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-5696564 9606 Homo sapiens Reactome Ubiquitin carboxyl-terminal hydrolase 25 20260222 UniProtKB Q9UHP3 USP25 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA GO_REF:0000052 9606 Homo sapiens HPA Ubiquitin carboxyl-terminal hydrolase 25 20251115 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000269 EXP PMID:23042150 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20251027 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000269 EXP PMID:37339955 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20251027 UniProtKB Q9UHP3 USP25 located_in GO:0005737 cytoplasm cellular_component ECO:0000269 EXP PMID:28619731 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20251027 UniProtKB Q9UHP3 USP25 located_in GO:0005737 cytoplasm cellular_component ECO:0000315 IMP PMID:38875478 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20250220 UniProtKB Q9UHP3 USP25 enables GO:0101005 deubiquitinase activity molecular_function ECO:0000315 IMP PMID:38875478 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20250219 UniProtKB Q9UHP3 USP25 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:19440361 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231213 UniProtKB Q9UHP3 USP25 enables GO:0101005 deubiquitinase activity molecular_function ECO:0000314 IDA PMID:37339955 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231213 UniProtKB Q9UHP3 USP25 involved_in GO:1902883 negative regulation of response to oxidative stress biological_process ECO:0000314 IDA PMID:37339955 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231213 UniProtKB Q9UHP3 USP25 is_active_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:2304215 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231212 UniProtKB Q9UHP3 USP25 enables GO:0101005 deubiquitinase activity molecular_function ECO:0000314 IDA PMID:23042150 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231212 UniProtKB Q9UHP3 USP25 involved_in GO:1903882 negative regulation of interleukin-17-mediated signaling pathway biological_process ECO:0000314 IDA PMID:23042150 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20231212 UniProtKB Q9UHP3 USP25 enables GO:0032183 SUMO binding molecular_function ECO:0000353 IPI PMID:18538659 UniProtKB:P63165 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20200207 UniProtKB Q9UHP3 USP25 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-5696564 9606 Homo sapiens Reactome Ubiquitin carboxyl-terminal hydrolase 25 20160519 UniProtKB Q9UHP3 USP25 enables GO:0019783 ubiquitin-like protein peptidase activity molecular_function ECO:0000303 NAS PMID:22590560 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150709 UniProtKB Q9UHP3 USP25 located_in GO:0005783 endoplasmic reticulum cellular_component ECO:0000314 IDA PMID:22590560 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 involved_in GO:0016579 protein deubiquitination biological_process ECO:0000314 IDA PMID:22590560 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 enables GO:0031625 ubiquitin protein ligase binding molecular_function ECO:0000353 IPI PMID:22590560 UniProtKB:Q86TM6 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 enables GO:0043130 ubiquitin binding molecular_function ECO:0000303 NAS PMID:22590560 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 enables GO:0051117 ATPase binding molecular_function ECO:0000353 IPI PMID:22590560 UniProtKB:P55072 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 involved_in GO:1904293 negative regulation of ERAD pathway biological_process ECO:0000315 IMP PMID:22590560 9606 Homo sapiens ParkinsonsUK-UCL Ubiquitin carboxyl-terminal hydrolase 25 20150609 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000315 IMP PMID:18538659 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20110811 UniProtKB Q9UHP3 USP25 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:18538659 UniProtKB:P55854 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20110811 UniProtKB Q9UHP3 USP25 involved_in GO:0070536 protein K63-linked deubiquitination biological_process ECO:0000315 IMP PMID:18538659 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20110811 UniProtKB Q9UHP3 USP25 involved_in GO:0071108 protein K48-linked deubiquitination biological_process ECO:0000315 IMP PMID:18538659 9606 Homo sapiens UniProt Ubiquitin carboxyl-terminal hydrolase 25 20110811 UniProtKB Q9UHP3 USP25 enables GO:0004843 cysteine-type deubiquitinase activity molecular_function ECO:0000304 TAS PMID:10644437 9606 Homo sapiens PINC Ubiquitin carboxyl-terminal hydrolase 25 20030904 UniProtKB Q9UHP3 USP25 involved_in GO:0006508 proteolysis biological_process ECO:0000304 TAS PMID:10644437 9606 Homo sapiens PINC Ubiquitin carboxyl-terminal hydrolase 25 20030904 UniProtKB Q9UHP3 USP25 enables GO:0008233 peptidase activity molecular_function ECO:0000304 TAS PMID:10644437 9606 Homo sapiens PINC Ubiquitin carboxyl-terminal hydrolase 25 20030904 UniProtKB Q9UHP3 USP25 involved_in GO:0036211 protein modification process biological_process ECO:0000304 TAS PMID:10644437 9606 Homo sapiens PINC Ubiquitin carboxyl-terminal hydrolase 25 20030904