GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q9UK41 VPS28 is_active_in GO:0005829 cytosol cellular_component ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000309785|RGD:1306537|UniProtKB:Q9UK41 9606 Homo sapiens GO_Central Vacuolar protein sorting-associated protein 28 homolog 20251029 UniProtKB Q9UK41 VPS28 enables GO:0043130 ubiquitin binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000309785|UniProtKB:Q9UK41 9606 Homo sapiens GO_Central Vacuolar protein sorting-associated protein 28 homolog 20251029 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000318 IBA GO_REF:0000033 FB:FBgn0021814|PANTHER:PTN000309785|SGD:S000005986|UniProtKB:Q9UK41|WB:WBGene00013598 9606 Homo sapiens GO_Central Vacuolar protein sorting-associated protein 28 homolog 20170228 UniProtKB Q9UK41 VPS28 involved_in GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000309785|PomBase:SPAC1B3.07c 9606 Homo sapiens GO_Central Vacuolar protein sorting-associated protein 28 homolog 20170228 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000501 IEA GO_REF:0000120 ARBA:ARBA00026622|InterPro:IPR007143 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 located_in GO:0005886 plasma membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0039 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 involved_in GO:0016236 macroautophagy biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027245 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 located_in GO:0031902 late endosome membrane cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0151 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 involved_in GO:0032509 endosome transport via multivesicular body sorting pathway biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR007143 9606 Homo sapiens InterPro Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 involved_in GO:0036258 multivesicular body assembly biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00027035 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 involved_in GO:0039702 viral budding via host ESCRT complex biological_process ECO:0000256 IEA GO_REF:0000117 ARBA:ARBA00028526 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20260428 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:16189514 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:19060904 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:P12757 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:Q16637 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:Q8N1B4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:21516116 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q8N6Y0 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25416956 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:25959826 UniProtKB:P42858 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:P12757 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:P14373 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q08379 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q16637 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q16637-3 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q8IYX7 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q8N1B4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q8N6Y0 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q8WWW0-2 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q99081-3 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q9H257-2 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q9H257-3 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q9H2G9 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:26871637 UniProtKB:Q9NS73-5 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q9BZE7 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28514442 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:31515488 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:32814053 UniProtKB:P42858 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9BZE7 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:Q99816 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:Q9H9H4 9606 Homo sapiens IntAct Vacuolar protein sorting-associated protein 28 homolog 20260425 UniProtKB Q9UK41 VPS28 located_in GO:0005829 cytosol cellular_component ECO:0000265 IEA GO_REF:0000107 UniProtKB:B5DEN9|ensembl:ENSRNOP00000019707 9606 Homo sapiens Ensembl Vacuolar protein sorting-associated protein 28 homolog 20260422 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000353 IPI PMID:18005716 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000353 IPI PMID:21757351 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000353 IPI PMID:32424346 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0005547 NAS PMID:32424346 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 involved_in GO:0036258 multivesicular body assembly biological_process ECO:0005547 NAS PMID:32424346 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 involved_in GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biological_process ECO:0005547 NAS PMID:32424346 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 involved_in GO:0090148 membrane fission biological_process ECO:0005547 NAS PMID:32424346 9606 Homo sapiens ComplexPortal Vacuolar protein sorting-associated protein 28 homolog 20240823 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15218037 UniProtKB:Q99816 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20220204 UniProtKB Q9UK41 VPS28 involved_in GO:0016236 macroautophagy biological_process ECO:0000304 TAS PMID:20588296 9606 Homo sapiens ParkinsonsUK-UCL Vacuolar protein sorting-associated protein 28 homolog 20161221 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000304 TAS PMID:20588296 9606 Homo sapiens ParkinsonsUK-UCL Vacuolar protein sorting-associated protein 28 homolog 20160118 UniProtKB Q9UK41 VPS28 involved_in GO:0036258 multivesicular body assembly biological_process ECO:0000304 TAS PMID:20588296 9606 Homo sapiens ParkinsonsUK-UCL Vacuolar protein sorting-associated protein 28 homolog 20160118 UniProtKB Q9UK41 VPS28 involved_in GO:0039702 viral budding via host ESCRT complex biological_process ECO:0000304 TAS PMID:20588296 9606 Homo sapiens ParkinsonsUK-UCL Vacuolar protein sorting-associated protein 28 homolog 20160118 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000314 IDA PMID:18005716 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150211 UniProtKB Q9UK41 VPS28 located_in GO:0005768 endosome cellular_component ECO:0000314 IDA PMID:17940959 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150211 UniProtKB Q9UK41 VPS28 located_in GO:0005886 plasma membrane cellular_component ECO:0000314 IDA PMID:17940959 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150211 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:15218037 UniProtKB:Q9H9H4 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150210 UniProtKB Q9UK41 VPS28 involved_in GO:0045732 positive regulation of protein catabolic process biological_process ECO:0000315 IMP PMID:11916981 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150203 UniProtKB Q9UK41 VPS28 involved_in GO:2000397 positive regulation of ubiquitin-dependent endocytosis biological_process ECO:0000315 IMP PMID:11916981 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150203 UniProtKB Q9UK41 VPS28 located_in GO:0005769 early endosome cellular_component ECO:0000314 IDA PMID:11916981 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150202 UniProtKB Q9UK41 VPS28 enables GO:0043130 ubiquitin binding molecular_function ECO:0000314 IDA PMID:11916981 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150202 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:11134028 UniProtKB:Q61187 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150129 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000314 IDA PMID:11134028 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20150129 UniProtKB Q9UK41 VPS28 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:23533145 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140714 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14519844 UniProtKB:Q99816 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140523 UniProtKB Q9UK41 VPS28 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:14505570 UniProtKB:Q99816 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140522 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000314 IDA PMID:20654576 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140205 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000314 IDA PMID:22232651 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140205 UniProtKB Q9UK41 VPS28 involved_in GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biological_process ECO:0000305 IC PMID:20654576 GO:0000813 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20140205 UniProtKB Q9UK41 VPS28 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19199708 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20131029 UniProtKB Q9UK41 VPS28 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:19056867 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20131024 UniProtKB Q9UK41 VPS28 located_in GO:0070062 extracellular exosome cellular_component ECO:0007005 HDA PMID:20458337 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20130829 UniProtKB Q9UK41 VPS28 part_of GO:0000813 ESCRT I complex cellular_component ECO:0000314 IDA PMID:21757351 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20130426 UniProtKB Q9UK41 VPS28 involved_in GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway biological_process ECO:0000315 IMP PMID:21757351 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20130426 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-184269 9606 Homo sapiens Reactome Vacuolar protein sorting-associated protein 28 homolog 20130213 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-3149434 9606 Homo sapiens Reactome Vacuolar protein sorting-associated protein 28 homolog 20130213 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-3159232 9606 Homo sapiens Reactome Vacuolar protein sorting-associated protein 28 homolog 20130213 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-917696 9606 Homo sapiens Reactome Vacuolar protein sorting-associated protein 28 homolog 20130213 UniProtKB Q9UK41 VPS28 located_in GO:0010008 endosome membrane cellular_component ECO:0000304 TAS Reactome:R-HSA-917730 9606 Homo sapiens Reactome Vacuolar protein sorting-associated protein 28 homolog 20130213 UniProtKB Q9UK41 VPS28 located_in GO:0005737 cytoplasm cellular_component ECO:0000314 IDA PMID:18077552 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20090629 UniProtKB Q9UK41 VPS28 involved_in GO:0031397 negative regulation of protein ubiquitination biological_process ECO:0000314 IDA PMID:18077552 9606 Homo sapiens UniProt Vacuolar protein sorting-associated protein 28 homolog 20090629 UniProtKB Q9UK41 VPS28 located_in GO:0005768 endosome cellular_component ECO:0000314 IDA PMID:11134028 9606 Homo sapiens MGI Vacuolar protein sorting-associated protein 28 homolog 20060112 UniProtKB Q9UK41 VPS28 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:11134028 9606 Homo sapiens MGI Vacuolar protein sorting-associated protein 28 homolog 20060112