GENE PRODUCT DB GENE PRODUCT ID SYMBOL QUALIFIER GO TERM GO NAME GO ASPECT ECO ID GO EVIDENCE CODE REFERENCE WITH/FROM TAXON ID TAXON NAME ASSIGNED BY GENE NAME DATE UniProtKB Q86UK7 ZNF598 enables GO:0043022 ribosome binding molecular_function ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000533381|UniProtKB:Q86UK7 9606 Homo sapiens GO_Central E3 ubiquitin-protein ligase ZNF598 20241120 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000318 IBA GO_REF:0000033 PANTHER:PTN000533381|SGD:S000002674|UniProtKB:Q86UK7 9606 Homo sapiens GO_Central E3 ubiquitin-protein ligase ZNF598 20231109 UniProtKB Q86UK7 ZNF598 located_in GO:0005829 cytosol cellular_component ECO:0007322 IEA GO_REF:0000044 UniProtKB-SubCell:SL-0091 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20260601 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000501 IEA GO_REF:0000120 InterPro:IPR044288|EC:2.3.2.27 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20260601 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000256 IEA GO_REF:0000002 InterPro:IPR044288 9606 Homo sapiens InterPro E3 ubiquitin-protein ligase ZNF598 20260601 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33053355 UniProtKB:O75420 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase ZNF598 20260530 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:33961781 UniProtKB:O75420 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase ZNF598 20260530 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:35271311 UniProtKB:P62258 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase ZNF598 20260530 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:36931259 UniProtKB:P62258 9606 Homo sapiens IntAct E3 ubiquitin-protein ligase ZNF598 20260530 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000304 TAS Reactome:R-HSA-9948299 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase ZNF598 20260316 UniProtKB Q86UK7 ZNF598 involved_in GO:0016567 protein ubiquitination biological_process ECO:0007322 IEA GO_REF:0000041 UniPathway:UPA00143 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20260227 UniProtKB Q86UK7 ZNF598 involved_in GO:1990261 pre-mRNA catabolic process biological_process ECO:0005547 NAS PMID:33053355 9606 Homo sapiens ComplexPortal E3 ubiquitin-protein ligase ZNF598 20250731 UniProtKB Q86UK7 ZNF598 enables GO:0004842 ubiquitin-protein transferase activity molecular_function ECO:0000304 TAS Reactome:R-HSA-9948301 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase ZNF598 20250712 UniProtKB Q86UK7 ZNF598 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948301 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase ZNF598 20250519 UniProtKB Q86UK7 ZNF598 located_in GO:0005829 cytosol cellular_component ECO:0000304 TAS Reactome:R-HSA-9948317 9606 Homo sapiens Reactome E3 ubiquitin-protein ligase ZNF598 20250519 UniProtKB Q86UK7 ZNF598 involved_in GO:0045947 negative regulation of translational initiation biological_process ECO:0000314 IDA PMID:28065601 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230221 UniProtKB Q86UK7 ZNF598 enables GO:0140517 protein-RNA adaptor activity molecular_function ECO:0000314 IDA PMID:32726578 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230221 UniProtKB Q86UK7 ZNF598 is_active_in GO:0022626 cytosolic ribosome cellular_component ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230216 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28685749 UniProtKB:P61077 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 is_active_in GO:0022626 cytosolic ribosome cellular_component ECO:0000314 IDA PMID:30293783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:28685749 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:30293783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0070534 protein K63-linked ubiquitination biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:28685749 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:30293783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:32579943 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:33581075 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:36302773 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 enables GO:0170011 stalled ribosome sensor activity molecular_function ECO:0000314 IDA PMID:30293783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20230215 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20210527 UniProtKB Q86UK7 ZNF598 involved_in GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process biological_process ECO:0000315 IMP PMID:32099016 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20210527 UniProtKB Q86UK7 ZNF598 located_in GO:0005829 cytosol cellular_component ECO:0000314 IDA PMID:28757607 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20210526 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28065601 UniProtKB:P23396 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28065601 UniProtKB:P46783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28065601 UniProtKB:P60866 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28132843 UniProtKB:P23396 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28132843 UniProtKB:P46783 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0005515 protein binding molecular_function ECO:0000353 IPI PMID:28132843 UniProtKB:P60866 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 involved_in GO:0006513 protein monoubiquitination biological_process ECO:0000314 IDA PMID:28065601 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 involved_in GO:0016567 protein ubiquitination biological_process ECO:0000315 IMP PMID:28132843 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0043022 ribosome binding molecular_function ECO:0000314 IDA PMID:28065601 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0043022 ribosome binding molecular_function ECO:0000314 IDA PMID:28132843 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000314 IDA PMID:28065601 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0061630 ubiquitin protein ligase activity molecular_function ECO:0000315 IMP PMID:28132843 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000314 IDA PMID:28065601 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 involved_in GO:0072344 rescue of stalled cytosolic ribosome biological_process ECO:0000315 IMP PMID:28132843 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20170307 UniProtKB Q86UK7 ZNF598 enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22658674 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20140203 UniProtKB Q86UK7 ZNF598 enables GO:0003723 RNA binding molecular_function ECO:0007005 HDA PMID:22681889 9606 Homo sapiens UniProt E3 ubiquitin-protein ligase ZNF598 20140203