Augmin (HAUS) complex in Drosophila melanogaster
Augmin is an eight-subunit complex that recruits the gamma-tubulin ring complex to the sides of existing microtubules, so that new microtubules branch from old ones. This microtubule-dependent nucleation amplifies microtubule number within the mitotic and meiotic spindle. In Drosophila the complex was first identified in S2 cells, where loss of augmin subunits reduces spindle microtubule density.
No molecular function is assigned: augmin is a structural adaptor that attaches the gamma-tubulin ring complex to the side of existing microtubules, and its subunits carry only microtubule binding and protein-macromolecule adaptor terms in GOA. FlyBase groups realized by this module: AUG (FBgg0001940). Participants were generated from the FlyBase gene-group membership and mapped to UniProtKB by projects/FLYBASE_GENE_GROUPS/generate_modules.py from module_specs/dmel_augmin_complex.yaml. None of the member genes has a gene review in this repository yet.
Derived QC
Recommended-field compliance
All recommended fields populated.
Module deep research
✗ none found
No MODULE:dmel_augmin_complex deep-research report alongside the module YAML.
Leaf nodes lacking representative members
✓ every leaf node grounds to a representative protein.
Template conformance
✓ every declared conforms_to bundle matches its template motif.
Function consistency and core coverage
No functional claims were checked. This does not establish consistency with gene or family reviews.
Gene-review completeness (0/8 grounded genes reviewed)
0 complete review(s) · 0 with deep research · 8 missing review · 0 reviewed but lacking deep research
| Gene | Review | Complete | Deep research |
|---|---|---|---|
| dgt5 Q7K4B4 | ✗ | — | — |
| dgt6 Q9VAP2 | ✗ | — | — |
| dgt2 Q9VKD6 | ✗ | — | — |
| msd5 Q9W0G6 | ✗ | — | — |
| msd1 Q9W0G7 | ✗ | — | — |
| wac Q9W0S8 | ✗ | — | — |
| dgt3 Q9W2P0 | ✗ | — | — |
| dgt4 Q9W4M8 | ✗ | — | — |
Details
Eight-subunit complex that tethers the gamma-tubulin ring complex to existing spindle microtubules for branching nucleation.