Augmin (HAUS) complex in Drosophila melanogaster

Augmin is an eight-subunit complex that recruits the gamma-tubulin ring complex to the sides of existing microtubules, so that new microtubules branch from old ones. This microtubule-dependent nucleation amplifies microtubule number within the mitotic and meiotic spindle. In Drosophila the complex was first identified in S2 cells, where loss of augmin subunits reduces spindle microtubule density.

MODULE:dmel_augmin_complexDRAFTCONCRETEProtein Complexmodules/dmel_augmin_complex.yaml
HAUS complexGO:0070652
FB:FBgg0001940
FlyBase gene group AUG: Augmin complex
FlyBase release FB2026_03 groups 8 D. melanogaster genes as augmin complex (AUG); this module models that group.
GO:0070652
HAUS complex
GO term grounding the module as HAUS complex.

No molecular function is assigned: augmin is a structural adaptor that attaches the gamma-tubulin ring complex to the side of existing microtubules, and its subunits carry only microtubule binding and protein-macromolecule adaptor terms in GOA. FlyBase groups realized by this module: AUG (FBgg0001940). Participants were generated from the FlyBase gene-group membership and mapped to UniProtKB by projects/FLYBASE_GENE_GROUPS/generate_modules.py from module_specs/dmel_augmin_complex.yaml. None of the member genes has a gene review in this repository yet.

9Nodes
8Parts
0Variant Sets
0Variants
8Annotons
0Connections

Derived QC

Recommended-field compliance

100.0% recommended fields populated

All recommended fields populated.

Module deep research

✗ none found

No MODULE:dmel_augmin_complex deep-research report alongside the module YAML.

Leaf nodes lacking representative members

✓ every leaf node grounds to a representative protein.

Template conformance

✓ every declared conforms_to bundle matches its template motif.

Function consistency and core coverage

No functional claims were checked. This does not establish consistency with gene or family reviews.

Gene-review completeness (0/8 grounded genes reviewed)

0 complete review(s) · 0 with deep research · 8 missing review · 0 reviewed but lacking deep research

Gene Review Complete Deep research
dgt5 Q7K4B4 ✗ — —
dgt6 Q9VAP2 ✗ — —
dgt2 Q9VKD6 ✗ — —
msd5 Q9W0G6 ✗ — —
msd1 Q9W0G7 ✗ — —
wac Q9W0S8 ✗ — —
dgt3 Q9W2P0 ✗ — —
dgt4 Q9W4M8 ✗ — —

Details

Context
Drosophila melanogasterNCBITaxon:7227
spindleGO:0005819
Augmin complexProtein Complexdmel_augmin_complex

Eight-subunit complex that tethers the gamma-tubulin ring complex to existing spindle microtubules for branching nucleation.

HAUS complexGO:0070652
Context
Drosophila melanogasterNCBITaxon:7227
spindleGO:0005819
Part 1: dgt2 subunit
dgt2Moduledmel_augmin_complex_dgt2

Annotons

dgt2 subunit
dmel_augmin_complex_dgt2_dgt2
Participant: Gene Product: dgt2
Gene Product:
Part 2: dgt3 subunit
dgt3Moduledmel_augmin_complex_dgt3

Annotons

dgt3 subunit
dmel_augmin_complex_dgt3_dgt3
Participant: Gene Product: dgt3
Gene Product:
Part 3: dgt4 subunit
dgt4Moduledmel_augmin_complex_dgt4

Annotons

dgt4 subunit
dmel_augmin_complex_dgt4_dgt4
Participant: Gene Product: dgt4
Gene Product:
Part 4: dgt5 subunit
dgt5Moduledmel_augmin_complex_dgt5

Annotons

dgt5 subunit
dmel_augmin_complex_dgt5_dgt5
Participant: Gene Product: dgt5
Gene Product:
Part 5: dgt6 subunit
dgt6Moduledmel_augmin_complex_dgt6

Annotons

dgt6 subunit
dmel_augmin_complex_dgt6_dgt6
Participant: Gene Product: dgt6
Gene Product:
Part 6: msd1 subunit
msd1Moduledmel_augmin_complex_msd1

Annotons

msd1 subunit
dmel_augmin_complex_msd1_msd1
Participant: Gene Product: msd1
Gene Product:
Part 7: msd5 subunit
msd5Moduledmel_augmin_complex_msd5

Annotons

msd5 subunit
dmel_augmin_complex_msd5_msd5
Participant: Gene Product: msd5
Gene Product:
Part 8: wac subunit
wacModuledmel_augmin_complex_wac

Annotons

wac subunit
dmel_augmin_complex_wac_wac
Participant: Gene Product: wac
Gene Product: