The cytoplasmic 80S ribosome translates nuclear-encoded mRNAs. It consists of a 40S small subunit, which binds mRNA and decodes it, and a 60S large subunit, which carries the peptidyl transferase centre and the polypeptide exit tunnel. Each subunit is built from ribosomal RNAs and dozens of ribosomal proteins named by the universal (u) and eukaryote-specific (e) nomenclature. In Drosophila several ribosomal proteins are encoded by duplicated genes, and some paralogs are expressed mainly in the germline or testis (for example RpL22-like). FlyBase therefore also defines testis-specific variant compositions of both subunits, in which RpS28-like, RpL22-like and RpL37-2 appear only in the testis variants.
The subunit parts follow the four FlyBase subgroups (RPS, RPL and their testis-specific variants); most proteins are shared and appear in both the canonical and the testis variant of a subunit. The variant groups record composition as curated by FlyBase; whether every listed paralog swap occurs in a single ribosome population in vivo is not established. FlyBase lists ribosomal proteins only, so rRNAs are not participants here, and some members (RpL24-like, a RLP24 ribosome biogenesis homolog; Rack1) are associated proteins rather than core rRNA-binding proteins. Ribosome biogenesis factors, translation factors and mitochondrial ribosomes are separate modules. FlyBase groups realized by this module: CRP (FBgg0000141). Subgroups folded into it: RPS, RPL, RPS-T, RPL-T. Participants were generated from the FlyBase gene-group membership and mapped to UniProtKB by projects/FLYBASE_GENE_GROUPS/generate_modules.py from module_specs/dmel_cytoplasmic_ribosome.yaml. None of the member genes has a gene review in this repository yet.
All recommended fields populated.
✗ none found
No MODULE:dmel_cytoplasmic_ribosome deep-research report alongside the module YAML.
✓ every leaf node grounds to a representative protein.
✓ every declared conforms_to bundle matches its template motif.
0 gene-function check(s) reflected in core functions · 0 conflict(s) · 0 evidence or coverage gap(s) (4 comparison(s))
Retained noncore functions are reported separately; they do not require promotion to core functions. Support from representative genes does not establish conservation across the whole family. Missing reviews or identifiers leave a claim unverified.
| Annoton | Participant | Function | Assessment |
|---|---|---|---|
| small_subunit_canonical_complex | PROTEIN_COMPLEX Gene |
structural constituent of ribosome GO:0003735 |
Participant Unchecked
No direct UniProt participant to compare. Abstract selectors and complex-wide activities cannot be inferred from donor or subunit gene reviews. |
| small_subunit_testis_complex | PROTEIN_COMPLEX Gene |
structural constituent of ribosome GO:0003735 |
Participant Unchecked
No direct UniProt participant to compare. Abstract selectors and complex-wide activities cannot be inferred from donor or subunit gene reviews. |
| large_subunit_canonical_complex | PROTEIN_COMPLEX Gene |
structural constituent of ribosome GO:0003735 |
Participant Unchecked
No direct UniProt participant to compare. Abstract selectors and complex-wide activities cannot be inferred from donor or subunit gene reviews. |
| large_subunit_testis_complex | PROTEIN_COMPLEX Gene |
structural constituent of ribosome GO:0003735 |
Participant Unchecked
No direct UniProt participant to compare. Abstract selectors and complex-wide activities cannot be inferred from donor or subunit gene reviews. |
0 complete review(s) · 0 with deep research · 94 missing review · 0 reviewed but lacking deep research
| Gene | Review | Complete | Deep research |
|---|---|---|---|
| RpLP0-like A1Z848 | ✗ | — | — |
| RpS15 A1ZAH8 | ✗ | — | — |
| RpL41 A1ZBY7 | ✗ | — | — |
| RpS28-like A8DYY3 | ✗ | — | — |
| RpS14a C0HKA0 | ✗ | — | — |
| RpS14b C0HKA1 | ✗ | — | — |
| RpL39 O16130 | ✗ | — | — |
| RpL3 O16797 | ✗ | — | — |
| RpL15 O17445 | ✗ | — | — |
| Rack1 O18640 | ✗ | — | — |
| RpL10 O61231 | ✗ | — | — |
| RpS21 O76927 | ✗ | — | — |
| RpL32 P04359 | ✗ | — | — |
| RpLP2 P05389 | ✗ | — | — |
| RpLP1 P08570 | ✗ | — | — |
| RpL4 P09180 | ✗ | — | — |
| RpS26 P13008 | ✗ | — | — |
| RpS27A P15357 | ✗ | — | — |
| RpS17 P17704 | ✗ | — | — |
| RpL40 P18101 | ✗ | — | — |
| RpLP0 P19889 | ✗ | — | — |
| RpS6 P29327 | ✗ | — | — |
| RpS2 P31009 | ✗ | — | — |
| RpL7 P32100 | ✗ | — | — |
| RpL19 P36241 | ✗ | — | — |
| sta P38979 | ✗ | — | — |
| RpS19a P39018 | ✗ | — | — |
| RpS4 P41042 | ✗ | — | — |
| RpL27A P41092 | ✗ | — | — |
| RpL18A P41093 | ✗ | — | — |
| RpS18 P41094 | ✗ | — | — |
| RpL13 P41126 | ✗ | — | — |
| RpL11 P46222 | ✗ | — | — |
| RpL7A P46223 | ✗ | — | — |
| RpS15Aa P48149 | ✗ | — | — |
| RpL23 P48159 | ✗ | — | — |
| RpS25 P48588 | ✗ | — | — |
| RpL36 P49630 | ✗ | — | — |
| RpL9 P50882 | ✗ | — | — |
| RpL22 P50887 | ✗ | — | — |
| RpS20 P55828 | ✗ | — | — |
| RpS3A P55830 | ✗ | — | — |
| RpL14 P55841 | ✗ | — | — |
| RpS9 P55935 | ✗ | — | — |
| RpS12 P80455 | ✗ | — | — |
| RpS13 Q03334 | ✗ | — | — |
| RpS3 Q06559 | ✗ | — | — |
| RpS11 Q0E9B6 | ✗ | — | — |
| RpL29 Q24154 | ✗ | — | — |
| RpS5a Q24186 | ✗ | — | — |
| RpL12 Q2MGM3 | ✗ | — | — |
| RpS15Ab Q7KR04 | ✗ | — | — |
| RpS19b Q7KS38 | ✗ | — | — |
| RpS8 Q8MLY8 | ✗ | — | — |
| RpS23 Q8T3U2 | ✗ | — | — |
| RpL8 Q9V3G1 | ✗ | — | — |
| RpL31 Q9V597 | ✗ | — | — |
| RpL21 Q9V9M7 | ✗ | — | — |
| RpL6 Q9V9W3 | ✗ | — | — |
| RpS7 Q9VA91 | ✗ | — | — |
| RpS28a Q9VAB9 | ✗ | — | — |
| RpS10a Q9VB14 | ✗ | — | — |
| RpL34a Q9VBH8 | ✗ | — | — |
| RpL27 Q9VBN5 | ✗ | — | — |
| RpS27 Q9VBU9 | ✗ | — | — |
| RpS30 Q9VDH8 | ✗ | — | — |
| RpL10Aa Q9VFE0 | ✗ | — | — |
| RpS5b Q9VFE4 | ✗ | — | — |
| RpL24-like Q9VGN9 | ✗ | — | — |
| RpS29 Q9VH69 | ✗ | — | — |
| RpL34b Q9VHE5 | ✗ | — | — |
| RpL30 Q9VJ19 | ✗ | — | — |
| RpL24 Q9VJY6 | ✗ | — | — |
| RpL7-like Q9VKC1 | ✗ | — | — |
| RpL36A Q9VLT7 | ✗ | — | — |
| RpL37A Q9VMU4 | ✗ | — | — |
| RpL35A Q9VNB9 | ✗ | — | — |
| RpL13A Q9VNE9 | ✗ | — | — |
| RpL18 Q9VS34 | ✗ | — | — |
| RpL10Ab Q9VTP4 | ✗ | — | — |
| RpL26 Q9VVU2 | ✗ | — | — |
| RpS10b Q9VWG3 | ✗ | — | — |
| RpL37-1 Q9VXX8 | ✗ | — | — |
| RpL28 Q9VZS5 | ✗ | — | — |
| RpL23A Q9W0A8 | ✗ | — | — |
| RpL22-like Q9W1T1 | ✗ | — | — |
| RpL37-2 Q9W1U6 | ✗ | — | — |
| RpS24 Q9W229 | ✗ | — | — |
| RpS16 Q9W237 | ✗ | — | — |
| RpS28b Q9W334 | ✗ | — | — |
| RpL17 Q9W3W8 | ✗ | — | — |
| RpL35 Q9W499 | ✗ | — | — |
| RpL38 Q9W5N2 | ✗ | — | — |
| RpL5 Q9W5R8 | ✗ | — | — |
40S and 60S cytoplasmic ribosomal subunits, with canonical and testis-specific paralog compositions.
FlyBase testis variant composition, with RpS28-like in place of RpS28b and lacking the RpS10b and RpS19a paralogs.
FlyBase testis variant composition, with RpL22-like and RpL37-2 in place of RpL22 and RpL37-1 and lacking RpL10Ab.