row_id gene_product_id symbol name qualifier go_id go_name go_evidence evidence_code reference with_from taxon_id taxon_name assigned_by date UniProtKB:A0A087WQT6!239282755 UniProtKB:A0A087WQT6 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033170 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0G2JGA2!299696483 UniProtKB:A0A0G2JGA2 Diablo Diablo, IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0G2JGS0!60693697 UniProtKB:A0A0G2JGS0 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0N4SW24!419450522 UniProtKB:A0A0N4SW24 Bcl2l13 BCL2 like 13 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR042398 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0N4SW63!389569348 UniProtKB:A0A0N4SW63 Bcl2l13 BCL2 like 13 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR042398 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0R4J1B9!150741270 UniProtKB:A0A0R4J1B9 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0R4J1K8!120869937 UniProtKB:A0A0R4J1K8 Trp63 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0U1RNT4!61180798 UniProtKB:A0A0U1RNT4 1600014C10Rik RIKEN cDNA 1600014C10 gene involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9NSK7;ensembl:ENSP00000313332 10090 Mus musculus Ensembl 20260724 UniProtKB:A0A0U1RPD5!419667666 UniProtKB:A0A0U1RPD5 Tfpt TCF3 (E2A) fusion partner involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033555 10090 Mus musculus InterPro 20260727 UniProtKB:A0A0U1RQ56!31292148 UniProtKB:A0A0U1RQ56 Tfpt TCF3 (E2A) fusion partner involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033555 10090 Mus musculus InterPro 20260727 UniProtKB:A0A158SIS7!330344889 UniProtKB:A0A158SIS7 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:A0A1S6GWH3!182552057 UniProtKB:A0A1S6GWH3 Birc6 Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022103 10090 Mus musculus InterPro 20260727 UniProtKB:A0A1S6GWH6!3338014 UniProtKB:A0A1S6GWH6 Birc6 Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022103 10090 Mus musculus InterPro 20260727 UniProtKB:A0A1W2P6J6!272461716 UniProtKB:A0A1W2P6J6 Dapk3 non-specific serine/threonine protein kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:A0A1W2P7L3!362060368 UniProtKB:A0A1W2P7L3 Dffb DNA fragmentation factor subunit beta involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:A0A2I3BR11!153748438 UniProtKB:A0A2I3BR11 Bcl2l2 Apoptosis regulator Bcl-2 family BH4 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:A0A2R8VI69!423207609 UniProtKB:A0A2R8VI69 Bik BCL2-interacting killer involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024579 10090 Mus musculus InterPro 20260727 UniProtKB:A0A2R8W6U8!154313629 UniProtKB:A0A2R8W6U8 Bik BCL2-interacting killer involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024579 10090 Mus musculus InterPro 20260727 UniProtKB:A0A494BAF0!455328196 UniProtKB:A0A494BAF0 Pou4f3 POU domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:A0A494BAM9!186450084 UniProtKB:A0A494BAM9 Pmaip1 Phorbol-12-myristate-13-acetate-induced protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024140 10090 Mus musculus InterPro 20260727 UniProtKB:A0A494BAU0!216331658 UniProtKB:A0A494BAU0 Pmaip1 Phorbol-12-myristate-13-acetate-induced protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024140 10090 Mus musculus InterPro 20260727 UniProtKB:A0A494BBC4!455328227 UniProtKB:A0A494BBC4 Bad BCL2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:A0A494BBP5!305975783 UniProtKB:A0A494BBP5 Fas Tumor necrosis factor receptor superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008063 10090 Mus musculus InterPro 20260727 UniProtKB:A0A571BF39!157740642 UniProtKB:A0A571BF39 Dapk2 Death-associated protein kinase 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:A0A5Q0MU23!307742617 UniProtKB:A0A5Q0MU23 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:A0A6G7MAJ9!159175203 UniProtKB:A0A6G7MAJ9 Xaf1 XIAP-associated factor 1 C-terminal domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR041386 10090 Mus musculus InterPro 20260727 UniProtKB:A1Y9B0!206065446 UniProtKB:A1Y9B0 Fasl Tumor necrosis factor ligand superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028326 10090 Mus musculus InterPro 20260727 UniProtKB:A1Y9B2!295718819 UniProtKB:A1Y9B2 Fas Tumor necrosis factor receptor superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008063 10090 Mus musculus InterPro 20260727 UniProtKB:A2A888!295721880 UniProtKB:A2A888 Tnfrsf9 TNFR-Cys domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR020413 10090 Mus musculus InterPro 20260727 UniProtKB:A2AHX7!146349406 UniProtKB:A2AHX7 Bcl2l1 Apoptosis regulator Bcl-2 family BH4 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:A2AHX8!86578402 UniProtKB:A2AHX8 Bcl2l1 Apoptosis regulator Bcl-2 family BH4 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:A2AHX9!26835246 UniProtKB:A2AHX9 Bcl2l1 Bcl-2-like protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:A2AS93!86578756 UniProtKB:A2AS93 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:A2AV74!116473279 UniProtKB:A2AV74 Bmf BCL2 modifying factor involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028192 10090 Mus musculus InterPro 20260727 UniProtKB:A2AV75!355459746 UniProtKB:A2AV75 Bmf BCL2 modifying factor involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028192 10090 Mus musculus InterPro 20260727 UniProtKB:A6PWD2!86655788 UniProtKB:A6PWD2 Fhad1 Forkhead-associated domain-containing protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:38563001 10090 Mus musculus MGI 20240924 UniProtKB:B1AU25!116659012 UniProtKB:B1AU25 Aifm1 Apoptosis-inducing factor 1, mitochondrial involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:O95831;ensembl:ENSP00000287295 10090 Mus musculus Ensembl 20260724 UniProtKB:B1AVB3!325778139 UniProtKB:B1AVB3 Scml2 MBT domain-containing protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:25634095 10090 Mus musculus MGI 20160810 UniProtKB:B1AX91!176380762 UniProtKB:B1AX91 Trp73 p53 DNA-binding domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:B2RWS6!206287231 UniProtKB:B2RWS6 Ep300 Histone acetyltransferase p300 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q09472;ensembl:ENSP00000263253 10090 Mus musculus Ensembl 20260724 UniProtKB:B2RWS6!206287232 UniProtKB:B2RWS6 Ep300 Histone acetyltransferase p300 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q09472 10090 Mus musculus GO_Central 20251030 UniProtKB:B2RWS6!206287233 UniProtKB:B2RWS6 Ep300 Histone acetyltransferase p300 involved_in GO:0006915 apoptotic process ISS ECO:0000250 PMID:9194565 UniProtKB:Q09472 10090 Mus musculus UniProt 20091215 UniProtKB:B7ZWE5!27183804 UniProtKB:B7ZWE5 Bcl10 B-cell lymphoma/leukemia 10 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033238 10090 Mus musculus InterPro 20260727 UniProtKB:D3YUE7!146938579 UniProtKB:D3YUE7 Gramd4 GRAM domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR037847 10090 Mus musculus InterPro 20260727 UniProtKB:D3YZR8!57309797 UniProtKB:D3YZR8 Bad BCL2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z0F7!326178356 UniProtKB:D3Z0F7 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z0I1!415799727 UniProtKB:D3Z0I1 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z1A6!27425174 UniProtKB:D3Z1A6 Cidec CIDE-N domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:D3Z2Q3!57309908 UniProtKB:D3Z2Q3 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z3K5!326178545 UniProtKB:D3Z3K5 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z4Q1!356044141 UniProtKB:D3Z4Q1 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:D3Z5F7!475535534 UniProtKB:D3Z5F7 Gm20521 Bcl-2-like protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:D3Z7K2!117059545 UniProtKB:D3Z7K2 Trp63 Transformation related protein 63 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:D6RET7!415838202 UniProtKB:D6RET7 Gramd4 GRAM domain containing 4 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR037847 10090 Mus musculus InterPro 20260727 UniProtKB:E5FYH1!415976337 UniProtKB:E5FYH1 Topaz1 Protein TOPAZ1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:26358182 MGI:MGI:5700076 10090 Mus musculus MGI 20160706 UniProtKB:E9JGN0!356269013 UniProtKB:E9JGN0 Dapk2 non-specific serine/threonine protein kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:E9Q4T8!27652524 UniProtKB:E9Q4T8 Cul3 Cullin-3 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:E9QMZ0!87396371 UniProtKB:E9QMZ0 Cidec Lipid transferase CIDEC involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:F6S493!326524512 UniProtKB:F6S493 Bad BCL2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:F6T5F5!475885302 UniProtKB:F6T5F5 Apaf1 Apoptotic peptidase activating factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:F6V3U4!27780388 UniProtKB:F6V3U4 Bcl2l12 BCL2 like 12 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:F6V780!266800130 UniProtKB:F6V780 Trp53 Transformation related protein 53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:F6WY57!57669137 UniProtKB:F6WY57 Bad BCL2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:F6XVK1!356403567 UniProtKB:F6XVK1 Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:21305608 MGI:MGI:5496553 10090 Mus musculus MGI 20190122 UniProtKB:F6XVK1!356403568 UniProtKB:F6XVK1 Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:23908015 10090 Mus musculus MGI 20191003 UniProtKB:F6YS55!147302693 UniProtKB:F6YS55 Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:35087090 10090 Mus musculus MGI 20240604 UniProtKB:F7ABX5!177145969 UniProtKB:F7ABX5 Bad BCL2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:F7AMM2!326544169 UniProtKB:F7AMM2 Gzmm Granzyme M (lymphocyte met-ase 1) involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P51124 10090 Mus musculus GO_Central 20260723 UniProtKB:F7ASJ6!475903256 UniProtKB:F7ASJ6 Trp63 Transformation related protein 63 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:F7ASK5!356411311 UniProtKB:F7ASK5 Trp63 Transformation related protein 63 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:F8WIZ9!356455490 UniProtKB:F8WIZ9 Tfpt INO80 complex subunit F domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033555 10090 Mus musculus InterPro 20260727 UniProtKB:G3UWJ4!27991091 UniProtKB:G3UWJ4 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3UWM7!267010565 UniProtKB:G3UWM7 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3UWR5!386475873 UniProtKB:G3UWR5 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3UWZ6!267010583 UniProtKB:G3UWZ6 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3UYM6!27991223 UniProtKB:G3UYM6 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3UYS2!87736553 UniProtKB:G3UYS2 Trp73 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:G3UZC0!57880120 UniProtKB:G3UZC0 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3X9M0!57889799 UniProtKB:G3X9M0 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:G3XA09!446257626 UniProtKB:G3XA09 Apaf1 Apoptotic protease-activating factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:H3BK76!476289178 UniProtKB:H3BK76 Trp73 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:I7HIK9!416724341 UniProtKB:I7HIK9 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:K3W4L7!416806754 UniProtKB:K3W4L7 Pbld1 Phenazine biosynthesis-like protein domain containing 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:O08586!387240831 UniProtKB:O08586 Pten Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:20418913 MGI:MGI:1921405 10090 Mus musculus MGI 20230726 UniProtKB:O08643!476867705 UniProtKB:O08643 Gzmm Peptidase S1 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P51124;ensembl:ENSP00000264553 10090 Mus musculus Ensembl 20260724 UniProtKB:O08715!58646355 UniProtKB:O08715 Akap1 A-kinase anchor protein 1, mitochondrial involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:32072193 10090 Mus musculus UniProt 20201130 UniProtKB:O08734!387241353 UniProtKB:O08734 Bak1 Bcl-2 homologous antagonist/killer acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:15967824 MGI:MGI:1197519 10090 Mus musculus MGI 20081231 UniProtKB:O08734!387241419 UniProtKB:O08734 Bak1 Bcl-2 homologous antagonist/killer involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q16611;ensembl:ENSP00000363591 10090 Mus musculus Ensembl 20260724 UniProtKB:O08734!387241420 UniProtKB:O08734 Bak1 Bcl-2 homologous antagonist/killer involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q16611 10090 Mus musculus GO_Central 20260723 UniProtKB:O08736!387241504 UniProtKB:O08736 Casp12 Caspase-12 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:12847083 10090 Mus musculus MGI 20081229 UniProtKB:O08736!387241520 UniProtKB:O08736 Casp12 Caspase-12 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:O08738!476868026 UniProtKB:O08738 Casp6 Caspase-6 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:O08811!297648636 UniProtKB:O08811 Ercc2 General transcription and DNA repair factor IIH helicase subunit XPD involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P18074 10090 Mus musculus UniProt 20041006 UniProtKB:O08811!297648637 UniProtKB:O08811 Ercc2 General transcription and DNA repair factor IIH helicase subunit XPD involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P18074;ensembl:ENSP00000375809 10090 Mus musculus Ensembl 20260724 UniProtKB:O08811!297648638 UniProtKB:O08811 Ercc2 General transcription and DNA repair factor IIH helicase subunit XPD involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P18074 10090 Mus musculus GO_Central 20260702 UniProtKB:O35280!118400270 UniProtKB:O35280 Chek1 Serine/threonine-protein kinase Chk1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O14757 10090 Mus musculus GO_Central 20250828 UniProtKB:O35379!297655507 UniProtKB:O35379 Abcc1 Multidrug resistance-associated protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:26822305 10090 Mus musculus MGI 20251217 UniProtKB:O35425!267784792 UniProtKB:O35425 Bok Bcl-2-related ovarian killer protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:70984 10090 Mus musculus GO_Central 20250828 UniProtKB:O35425!267784793 UniProtKB:O35425 Bok Bcl-2-related ovarian killer protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9UMX3 10090 Mus musculus GO_Central 20250828 UniProtKB:O35425!267784794 UniProtKB:O35425 Bok Bcl-2-related ovarian killer protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:Q792S6;ensembl:ENSRNOP00000024693;UniProtKB:Q9UMX3;ensembl:ENSP00000314132 10090 Mus musculus UniProt 20260724 UniProtKB:O35464!447019085 UniProtKB:O35464 Sema6a Semaphorin-6A involved_in GO:0006915 apoptotic process NAS ECO:0000303 PMID:10993894 10090 Mus musculus UniProt 20030710 UniProtKB:O35516!118400570 UniProtKB:O35516 Notch2 Neurogenic locus notch homolog protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022336 10090 Mus musculus InterPro 20260727 UniProtKB:O35732!88509041 UniProtKB:O35732 Cflar CASP8 and FADD-like apoptosis regulator involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:O35732!88509042 UniProtKB:O35732 Cflar CASP8 and FADD-like apoptosis regulator involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O15519 10090 Mus musculus GO_Central 20250828 UniProtKB:O35843!118401135 UniProtKB:O35843 Bcl2l1 Bcl-2-like protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:O35912!297656211 UniProtKB:O35912 Emp3 Epithelial membrane protein 3 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P54852;ensembl:ENSP00000270221 10090 Mus musculus Ensembl 20260724 UniProtKB:O35912!297656212 UniProtKB:O35912 Emp3 Epithelial membrane protein 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P54852 10090 Mus musculus GO_Central 20260723 UniProtKB:O54784!327520448 UniProtKB:O54784 Dapk3 Death-associated protein kinase 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:621766 10090 Mus musculus GO_Central 20260723 UniProtKB:O54784!327520449 UniProtKB:O54784 Dapk3 Death-associated protein kinase 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O43293 10090 Mus musculus GO_Central 20260723 UniProtKB:O54784!327520450 UniProtKB:O54784 Dapk3 Death-associated protein kinase 3 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:O43293;ensembl:ENSP00000442973 10090 Mus musculus UniProt 20260724 UniProtKB:O54786!178122653 UniProtKB:O54786 Dffa DNA fragmentation factor subunit alpha involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR003508 10090 Mus musculus InterPro 20260727 UniProtKB:O54786!178122654 UniProtKB:O54786 Dffa DNA fragmentation factor subunit alpha involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0024732;MGI:MGI:1196227;MGI:MGI:1270844;PANTHER:PTN000959605;UniProtKB:Q96AQ7;UniProtKB:Q9UHD4 10090 Mus musculus GO_Central 20250320 UniProtKB:O54788!28771183 UniProtKB:O54788 Dffb DNA fragmentation factor subunit beta involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR003508 10090 Mus musculus InterPro 20260727 UniProtKB:O54907!447024392 UniProtKB:O54907 Tnfsf12 Tumor necrosis factor ligand superfamily member 12 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:O54940!208006475 UniProtKB:O54940 Bnip2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:7954800 UniProtKB:Q12982 10090 Mus musculus MGI 20060110 UniProtKB:O54940!208006487 UniProtKB:O54940 Bnip2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN000251507;UniProtKB:Q7Z465 10090 Mus musculus GO_Central 20230110 UniProtKB:O55003!327520763 UniProtKB:O55003 Bnip3 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:7954800 UniProtKB:Q12983 10090 Mus musculus MGI 20060113 UniProtKB:O70302!208010901 UniProtKB:O70302 Cidea Lipid transferase CIDEA involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR003508 10090 Mus musculus InterPro 20260727 UniProtKB:O70302!208010902 UniProtKB:O70302 Cidea Lipid transferase CIDEA involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0024732;MGI:MGI:1196227;MGI:MGI:1270844;PANTHER:PTN000959605;UniProtKB:Q96AQ7;UniProtKB:Q9UHD4 10090 Mus musculus GO_Central 20250320 UniProtKB:O70303!357394825 UniProtKB:O70303 Cideb Lipid transferase CIDEB acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:12429024 UniProtKB:Q9UHD4 10090 Mus musculus MGI 20130715 UniProtKB:O70303!357394833 UniProtKB:O70303 Cideb Lipid transferase CIDEB involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0024732;MGI:MGI:1196227;MGI:MGI:1270844;PANTHER:PTN000959605;UniProtKB:Q96AQ7;UniProtKB:Q9UHD4 10090 Mus musculus GO_Central 20250320 UniProtKB:O70303!357394834 UniProtKB:O70303 Cideb Lipid transferase CIDEB involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;InterPro:IPR003508 10090 Mus musculus UniProt 20260727 UniProtKB:O70325!297666274 UniProtKB:O70325 Gpx4 Phospholipid hydroperoxide glutathione peroxidase GPX4 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:24599700 10090 Mus musculus MGI 20240605 UniProtKB:O70337!297666358 UniProtKB:O70337 Bik Bcl-2-interacting killer involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024579 10090 Mus musculus InterPro 20260727 UniProtKB:O70366!387258914 UniProtKB:O70366 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:O88662!357400000 UniProtKB:O88662 Emp2 Epithelial membrane protein 2 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P54851 10090 Mus musculus UniProt 20230203 UniProtKB:O88662!357400001 UniProtKB:O88662 Emp2 Epithelial membrane protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P54851;ensembl:ENSP00000352540 10090 Mus musculus Ensembl 20260724 UniProtKB:O88662!357400002 UniProtKB:O88662 Emp2 Epithelial membrane protein 2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P54851 10090 Mus musculus GO_Central 20260723 UniProtKB:O88738!88525260 UniProtKB:O88738 Birc6 Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022103 10090 Mus musculus InterPro 20260727 UniProtKB:O88879!267801222 UniProtKB:O88879 Apaf1 Apoptotic protease-activating factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:O88898!357400171 UniProtKB:O88898 Tp63 Tumor protein 63 acts_upstream_of_or_within GO:0006915 apoptotic process TAS ECO:0000304 PMID:14555234 10090 Mus musculus MGI 20041210 UniProtKB:O88898!357400265 UniProtKB:O88898 Tp63 Tumor protein 63 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:O89110!417156231 UniProtKB:O89110 Casp8 Caspase-8 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:Q14790 10090 Mus musculus MGI 20070906 UniProtKB:O89110!417156232 UniProtKB:O89110 Casp8 Caspase-8 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:16183742 10090 Mus musculus MGI 20060331 UniProtKB:O89110!417156318 UniProtKB:O89110 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:O89110!417156319 UniProtKB:O89110 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q14790 10090 Mus musculus GO_Central 20260723 UniProtKB:O89110!417156320 UniProtKB:O89110 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 UniProtKB:Q14790;ensembl:ENSP00000501268;InterPro:IPR033170 10090 Mus musculus UniProt 20260727 UniProtKB:P01580!327537027 UniProtKB:P01580 Ifng Interferon gamma acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:P01579 10090 Mus musculus MGI 20120105 UniProtKB:P01582!387270458 UniProtKB:P01582 Il1a Interleukin-1 alpha involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:P01590!28785872 UniProtKB:P01590 Il2ra Interleukin-2 receptor subunit alpha involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:P02340!58676271 UniProtKB:P02340 Tp53 Cellular tumor antigen p53 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:16183742 10090 Mus musculus MGI 20060324 UniProtKB:P02340!58676272 UniProtKB:P02340 Tp53 Cellular tumor antigen p53 acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:17325035 MGI:MGI:1343101 10090 Mus musculus MGI 20090915 UniProtKB:P02340!58676599 UniProtKB:P02340 Tp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:P02340!58676600 UniProtKB:P02340 Tp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:17434459 10090 Mus musculus MGI 20220718 UniProtKB:P02772!148298593 UniProtKB:P02772 Afp Alpha-fetoprotein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:36301669 10090 Mus musculus MGI 20240611 UniProtKB:P07321!476902438 UniProtKB:P07321 Epo Erythropoietin acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:17300687 10090 Mus musculus MGI 20080206 UniProtKB:P10417!297694532 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:8022822 UniProtKB:P10415 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694533 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8170972 MGI:MGI:2156165 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694534 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8372353 MGI:MGI:2156165 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694535 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8372353 MGI:MGI:2156165 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694536 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8372353 MGI:MGI:2156165 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694537 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8372353 MGI:MGI:2156165 10090 Mus musculus MGI 20140528 UniProtKB:P10417!297694538 UniProtKB:P10417 Bcl2 Apoptosis regulator Bcl-2 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:8949945 UniProtKB:P10415 10090 Mus musculus MGI 20140528 UniProtKB:P11103!417178761 UniProtKB:P11103 Parp1 Poly [ADP-ribose] polymerase 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P09874 10090 Mus musculus GO_Central 20260402 UniProtKB:P11352!267821590 UniProtKB:P11352 Gpx1 Glutathione peroxidase 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16934683 MGI:MGI:2158814 10090 Mus musculus MGI 20210322 UniProtKB:P11352!267821591 UniProtKB:P11352 Gpx1 Glutathione peroxidase 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16962942 MGI:MGI:2158814 10090 Mus musculus MGI 20080211 UniProtKB:P11531!88548353 UniProtKB:P11531 Dmd Dystrophin acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:20716577 MGI:MGI:1856328 10090 Mus musculus MGI 20230926 UniProtKB:P12813!447059557 UniProtKB:P12813 Nr4a1 Nuclear receptor subfamily 4 group A member 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:17434920 MGI:MGI:2182325 10090 Mus musculus MGI 20110617 UniProtKB:P12815!88550099 UniProtKB:P12815 Pdcd6 Programmed cell death protein 6 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:8560270 10090 Mus musculus MGI 20070821 UniProtKB:P13405!58697188 UniProtKB:P13405 Rb1 Retinoblastoma-associated protein involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:18638549 10090 Mus musculus MGI 20210609 UniProtKB:P15314!88552319 UniProtKB:P15314 Irf1 Interferon regulatory factor 1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P10914 10090 Mus musculus UniProt 20120408 UniProtKB:P15314!88552320 UniProtKB:P15314 Irf1 Interferon regulatory factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P10914;ensembl:ENSP00000245414 10090 Mus musculus Ensembl 20260724 UniProtKB:P15314!88552321 UniProtKB:P15314 Irf1 Interferon regulatory factor 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P10914 10090 Mus musculus GO_Central 20260723 UniProtKB:P15975!28808316 UniProtKB:P15975 Usp53 Ubiquitin carboxyl-terminal hydrolase 53 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:26609154 MGI:MGI:3708452 10090 Mus musculus MGI 20160629 UniProtKB:P16646!28809086 UniProtKB:P16646 Pmp22 Peripheral myelin protein 22 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q01453 10090 Mus musculus GO_Central 20260723 UniProtKB:P16951!267825924 UniProtKB:P16951 Atf2 Cyclic AMP-dependent transcription factor ATF-2 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:17189429 MGI:MGI:1857283 10090 Mus musculus MGI 20210608 UniProtKB:P17208!387292484 UniProtKB:P17208 Pou4f1 POU domain, class 4, transcription factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:P17742!58702157 UniProtKB:P17742 Ppia Peptidyl-prolyl cis-trans isomerase A involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P62937 10090 Mus musculus UniProt 20200623 UniProtKB:P17742!58702158 UniProtKB:P17742 Ppia Peptidyl-prolyl cis-trans isomerase A involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P62937 10090 Mus musculus GO_Central 20260723 UniProtKB:P19973!357432559 UniProtKB:P19973 Lsp1 Lymphocyte-specific protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process TAS ECO:0000304 PMID:10961883 10090 Mus musculus MGI 20001107 UniProtKB:P20334!118447138 UniProtKB:P20334 Tnfrsf9 Tumor necrosis factor receptor superfamily member 9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR020413 10090 Mus musculus InterPro 20260727 UniProtKB:P22366!208048692 UniProtKB:P22366 Myd88 Myeloid differentiation primary response protein MyD88 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q99836;ensembl:ENSP00000498360 10090 Mus musculus Ensembl 20260724 UniProtKB:P22366!208048693 UniProtKB:P22366 Myd88 Myeloid differentiation primary response protein MyD88 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q99836 10090 Mus musculus GO_Central 20260702 UniProtKB:P22561!178167318 UniProtKB:P22561 Wt1 Wilms tumor protein homolog acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16418481 10090 Mus musculus MGI 20140828 UniProtKB:P23804!178168447 UniProtKB:P23804 Mdm2 E3 ubiquitin-protein ligase Mdm2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q00987 10090 Mus musculus GO_Central 20260702 UniProtKB:P23804!178168448 UniProtKB:P23804 Mdm2 E3 ubiquitin-protein ligase Mdm2 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:Q00987;ensembl:ENSP00000258149 10090 Mus musculus UniProt 20260724 UniProtKB:P23804!178168449 UniProtKB:P23804 Mdm2 E3 ubiquitin-protein ligase Mdm2 involved_in GO:0006915 apoptotic process IDA ECO:0000314 PMID:30879903 10090 Mus musculus UniProt 20201130 UniProtKB:P23950!118450397 UniProtKB:P23950 Zfp36l1 mRNA decay activator protein ZFP36L1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:15226444 MGI:MGI:3050540 10090 Mus musculus MGI 20140826 UniProtKB:P24622!267833682 UniProtKB:P24622 Cryaa Alpha-crystallin A chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:18056999 MGI:MGI:3777403 10090 Mus musculus MGI 20100120 UniProtKB:P25118!178170092 UniProtKB:P25118 Tnfrsf1a Tumor necrosis factor receptor superfamily member 1A involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:17884256 10090 Mus musculus MGI 20211025 UniProtKB:P25446!148325213 UniProtKB:P25446 Fas Tumor necrosis factor receptor superfamily member 6 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:P25445 10090 Mus musculus MGI 20070812 UniProtKB:P25446!148325214 UniProtKB:P25446 Fas Tumor necrosis factor receptor superfamily member 6 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8700551 MGI:MGI:1856334 10090 Mus musculus MGI 20080304 UniProtKB:P25446!148325215 UniProtKB:P25446 Fas Tumor necrosis factor receptor superfamily member 6 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:8700551 MGI:MGI:1856334 10090 Mus musculus MGI 20080304 UniProtKB:P25446!148325292 UniProtKB:P25446 Fas Tumor necrosis factor receptor superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008063 10090 Mus musculus InterPro 20260727 UniProtKB:P26645!88562973 UniProtKB:P26645 Marcks Myristoylated alanine-rich C-kinase substrate involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:30655546 10090 Mus musculus MGI 20211207 UniProtKB:P28867!28820742 UniProtKB:P28867 Prkcd Protein kinase C delta type involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q05655 10090 Mus musculus UniProt 20200518 UniProtKB:P28867!28820743 UniProtKB:P28867 Prkcd Protein kinase C delta type involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:67383 10090 Mus musculus GO_Central 20260723 UniProtKB:P28867!28820744 UniProtKB:P28867 Prkcd Protein kinase C delta type involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q05655;ensembl:ENSP00000331602 10090 Mus musculus Ensembl 20260724 UniProtKB:P28867!28820745 UniProtKB:P28867 Prkcd Protein kinase C delta type involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q05655 10090 Mus musculus GO_Central 20260723 UniProtKB:P29594!327571555 UniProtKB:P29594 Casp2 Caspase-2 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:P35396!297717186 UniProtKB:P35396 Ppard Peroxisome proliferator-activated receptor delta involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q03181;ensembl:ENSP00000353916 10090 Mus musculus Ensembl 20260724 UniProtKB:P35396!297717187 UniProtKB:P35396 Ppard Peroxisome proliferator-activated receptor delta involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q03181 10090 Mus musculus GO_Central 20260723 UniProtKB:P35639!148333914 UniProtKB:P35639 Ddit3 DNA damage-inducible transcript 3 protein involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:22265908 10090 Mus musculus UniProt 20121008 UniProtKB:P37242!267844378 UniProtKB:P37242 Thrb Thyroid hormone receptor beta acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:20203194 10090 Mus musculus MGI 20190827 UniProtKB:P41047!237953863 UniProtKB:P41047 Faslg Tumor necrosis factor ligand superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028326 10090 Mus musculus InterPro 20260727 UniProtKB:P43028!178184926 UniProtKB:P43028 Gdf6 Growth/differentiation factor 6 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P85857 10090 Mus musculus UniProt 20131119 UniProtKB:P46099!267852036 UniProtKB:P46099 Klf1 Krueppel-like factor 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:22835905 10090 Mus musculus MGI 20190805 UniProtKB:P47801!28837237 UniProtKB:P47801 Emp1 Epithelial membrane protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P54849;ensembl:ENSP00000256951 10090 Mus musculus Ensembl 20260724 UniProtKB:P47801!28837238 UniProtKB:P47801 Emp1 Epithelial membrane protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P54849 10090 Mus musculus GO_Central 20260723 UniProtKB:P49135!387320491 UniProtKB:P49135 Ercc3 General transcription and DNA repair factor IIH helicase/translocase subunit XPB involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P19447 10090 Mus musculus UniProt 20041006 UniProtKB:P49135!387320492 UniProtKB:P49135 Ercc3 General transcription and DNA repair factor IIH helicase/translocase subunit XPB involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P19447;ensembl:ENSP00000285398 10090 Mus musculus Ensembl 20260724 UniProtKB:P49135!387320493 UniProtKB:P49135 Ercc3 General transcription and DNA repair factor IIH helicase/translocase subunit XPB involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P19447 10090 Mus musculus GO_Central 20260723 UniProtKB:P49615!387320952 UniProtKB:P49615 Cdk5 Cyclin-dependent kinase 5 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:9126296 10090 Mus musculus MGI 20080215 UniProtKB:P49935!237961939 UniProtKB:P49935 Ctsh Pro-cathepsin H involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 GO:0008656;GO:0016505 10090 Mus musculus UniProt 20260727 UniProtKB:P51682!476948832 UniProtKB:P51682 Ccr5 C-C chemokine receptor type 5 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:36301669 10090 Mus musculus MGI 20240611 UniProtKB:P56198!357465707 UniProtKB:P56198 Cidec Lipid transferase CIDEC acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:12429024 UniProtKB:Q96AQ7 10090 Mus musculus MGI 20130715 UniProtKB:P56198!357465719 UniProtKB:P56198 Cidec Lipid transferase CIDEC involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR003508 10090 Mus musculus InterPro 20260727 UniProtKB:P56198!357465720 UniProtKB:P56198 Cidec Lipid transferase CIDEC involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0024732;MGI:MGI:1196227;MGI:MGI:1270844;PANTHER:PTN000959605;UniProtKB:Q96AQ7;UniProtKB:Q9UHD4 10090 Mus musculus GO_Central 20250320 UniProtKB:P56380!58736856 UniProtKB:P56380 Nudt2 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] involved_in GO:0006915 apoptotic process ISS ECO:0000250 PMID:11937063 UniProtKB:Q9U2M7 10090 Mus musculus UniProt 20150724 UniProtKB:P56726!476953079 UniProtKB:P56726 Smo Protein smoothened acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:35353806 10090 Mus musculus MGI 20221102 UniProtKB:P56812!357466202 UniProtKB:P56812 Pdcd5 Programmed cell death protein 5 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:O14737 10090 Mus musculus MGI 20101104 UniProtKB:P58686!327596231 UniProtKB:P58686 Bbln Bublin coiled-coil protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:32569872 10090 Mus musculus MGI 20240723 UniProtKB:P58801!88589629 UniProtKB:P58801 Ripk2 Receptor-interacting serine/threonine-protein kinase 2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:O43353;ensembl:ENSP00000220751 10090 Mus musculus Ensembl 20260724 UniProtKB:P58801!88589630 UniProtKB:P58801 Ripk2 Receptor-interacting serine/threonine-protein kinase 2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O43353 10090 Mus musculus GO_Central 20260702 UniProtKB:P59017!178197436 UniProtKB:P59017 Bcl2l13 Bcl-2-like protein 13 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:P59017!178197437 UniProtKB:P59017 Bcl2l13 Bcl-2-like protein 13 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:31266807 10090 Mus musculus MGI 20240724 UniProtKB:P59017!178197444 UniProtKB:P59017 Bcl2l13 Bcl-2-like protein 13 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR042398 10090 Mus musculus InterPro 20260727 UniProtKB:P61364!417224159 UniProtKB:P61364 Ostn Osteocrin acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:38232727 10090 Mus musculus MGI 20260224 UniProtKB:P62878!267868315 UniProtKB:P62878 Rbx1 E3 ubiquitin-protein ligase RBX1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P62877 10090 Mus musculus GO_Central 20250828 UniProtKB:P62897!297743178 UniProtKB:P62897 Cycs Cytochrome c, somatic acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:16757556 10090 Mus musculus MGI 20130610 UniProtKB:P68040!58744294 UniProtKB:P68040 Rack1 Small ribosomal subunit protein RACK1 involved_in GO:0006915 apoptotic process IEA ECO:0000364 GO_REF:0000108 GO:0008656 10090 Mus musculus GOC 20260727 UniProtKB:P70343!88598147 UniProtKB:P70343 Casp4 Caspase-4 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:P70377!208089531 UniProtKB:P70377 Fgf13 Fibroblast growth factor 13 NOT|involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:22726441 10090 Mus musculus UniProt 20120704 UniProtKB:P70419!447106888 UniProtKB:P70419 Galnt3 Polypeptide N-acetylgalactosaminyltransferase 3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:25107907 10090 Mus musculus MGI 20241008 UniProtKB:P70677!28856125 UniProtKB:P70677 Casp3 Caspase-3 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:12847083 10090 Mus musculus MGI 20081229 UniProtKB:P70677!28856126 UniProtKB:P70677 Casp3 Caspase-3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:12970760 MGI:MGI:2178778 10090 Mus musculus MGI 20150325 UniProtKB:P70677!28856127 UniProtKB:P70677 Casp3 Caspase-3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16469926 MGI:MGI:2158753 10090 Mus musculus MGI 20150325 UniProtKB:P70677!28856128 UniProtKB:P70677 Casp3 Caspase-3 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:17901126 10090 Mus musculus MGI 20110309 UniProtKB:P70677!28856129 UniProtKB:P70677 Casp3 Caspase-3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:9512515 MGI:MGI:2178778 10090 Mus musculus MGI 20150325 UniProtKB:P70677!28856217 UniProtKB:P70677 Casp3 Caspase-3 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:P70677!28856218 UniProtKB:P70677 Casp3 Caspase-3 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P42574;ensembl:ENSP00000311032 10090 Mus musculus Ensembl 20260724 UniProtKB:P70677!28856219 UniProtKB:P70677 Casp3 Caspase-3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P42574 10090 Mus musculus GO_Central 20260723 UniProtKB:P70677!28856220 UniProtKB:P70677 Casp3 Caspase-3 involved_in GO:0006915 apoptotic process IDA ECO:0000314 PMID:24378336 10090 Mus musculus MGI 20260615 UniProtKB:P97299!148367167 UniProtKB:P97299 Sfrp2 Secreted frizzled-related protein 2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:18729207 MGI:MGI:3810257 10090 Mus musculus MGI 20100112 UniProtKB:P97310!447113961 UniProtKB:P97310 Mcm2 DNA replication licensing factor MCM2 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P49736 10090 Mus musculus UniProt 20161025 UniProtKB:P97310!447113962 UniProtKB:P97310 Mcm2 DNA replication licensing factor MCM2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P49736;ensembl:ENSP00000265056 10090 Mus musculus Ensembl 20260724 UniProtKB:P97310!447113963 UniProtKB:P97310 Mcm2 DNA replication licensing factor MCM2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P49736 10090 Mus musculus GO_Central 20260723 UniProtKB:P97436!118495560 UniProtKB:P97436 Nkx3-1 Homeobox protein Nkx-3.1 involved_in GO:0006915 apoptotic process IEA ECO:0000364 GO_REF:0000108 GO:0008656 10090 Mus musculus GOC 20260727 UniProtKB:P97794!208098427 UniProtKB:P97794 Kcnj8 ATP-sensitive inward rectifier potassium channel 8 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:24498880 MGI:MGI:3720053 10090 Mus musculus MGI 20230417 UniProtKB:P97794!208098428 UniProtKB:P97794 Kcnj8 ATP-sensitive inward rectifier potassium channel 8 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:30315808 10090 Mus musculus MGI 20230418 UniProtKB:P97821!447114706 UniProtKB:P97821 Ctsc Dipeptidyl peptidase 1 involved_in GO:0006915 apoptotic process IEA ECO:0000364 GO_REF:0000108 GO:0016505 10090 Mus musculus GOC 20260727 UniProtKB:P97864!208098551 UniProtKB:P97864 Casp7 Caspase-7 acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:16469926 MGI:MGI:107739 10090 Mus musculus MGI 20150325 UniProtKB:P97864!208098587 UniProtKB:P97864 Casp7 Caspase-7 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:P97864!208098588 UniProtKB:P97864 Casp7 Caspase-7 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P55210;ensembl:ENSP00000358324 10090 Mus musculus Ensembl 20260724 UniProtKB:P97864!208098589 UniProtKB:P97864 Casp7 Caspase-7 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P55210 10090 Mus musculus GO_Central 20260723 UniProtKB:Q04857!417248889 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:14625552 MGI:MGI:2153356 10090 Mus musculus MGI 20230919 UniProtKB:Q04857!417248890 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:19293339 MGI:MGI:2145814 10090 Mus musculus MGI 20230926 UniProtKB:Q04857!417248891 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:20716577 MGI:MGI:2153356 10090 Mus musculus MGI 20230926 UniProtKB:Q04857!417248892 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:21037586 MGI:MGI:2153356 10090 Mus musculus MGI 20230927 UniProtKB:Q04857!417248893 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:22024752 MGI:MGI:2153356 10090 Mus musculus MGI 20231024 UniProtKB:Q04857!417248894 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:22343710 MGI:MGI:2153356 10090 Mus musculus MGI 20231004 UniProtKB:Q04857!417248895 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:24852368 MGI:MGI:2153356 10090 Mus musculus MGI 20231004 UniProtKB:Q04857!417248896 UniProtKB:Q04857 Col6a1 Collagen alpha-1(VI) chain acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:26565691 MGI:MGI:2153356 10090 Mus musculus MGI 20231010 UniProtKB:Q05A21!297765565 UniProtKB:Q05A21 Dapk3 non-specific serine/threonine protein kinase involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:O43293;ensembl:ENSP00000442973 10090 Mus musculus UniProt 20260724 UniProtKB:Q07813!267893861 UniProtKB:Q07813 Bax Apoptosis regulator BAX acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:10201940 MGI:MGI:1857429 10090 Mus musculus MGI 20080410 UniProtKB:Q07813!267893862 UniProtKB:Q07813 Bax Apoptosis regulator BAX acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:9560217 10090 Mus musculus MGI 20020612 UniProtKB:Q07813!267894053 UniProtKB:Q07813 Bax Apoptosis regulator BAX involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q07812;ensembl:ENSP00000263262 10090 Mus musculus Ensembl 20260724 UniProtKB:Q07813!267894054 UniProtKB:Q07813 Bax Apoptosis regulator BAX involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q07812 10090 Mus musculus GO_Central 20260723 UniProtKB:Q0P5X1!28895780 UniProtKB:Q0P5X1 Lrriq1 Leucine-rich repeat- and IQ domain-containing protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:36129630 10090 Mus musculus MGI 20250127 UniProtKB:Q2TBA3!297863806 UniProtKB:Q2TBA3 Malt1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q3T9W4!178352466 UniProtKB:Q3T9W4 Bcl2l1 Bcl-2-like protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:Q3TAQ6!148505583 UniProtKB:Q3TAQ6 Bmf Uncharacterized protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028192 10090 Mus musculus InterPro 20260727 UniProtKB:Q3TBX2!118636391 UniProtKB:Q3TBX2 Tnfsf12 Tumor necrosis factor ligand superfamily member 12 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3TEL3!58892912 UniProtKB:Q3TEL3 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:Q3TFU7!268021523 UniProtKB:Q3TFU7 Bad Bcl2 antagonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:Q3TH93!58892994 UniProtKB:Q3TH93 Bok Bcl-2-related ovarian killer protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:Q792S6;ensembl:ENSRNOP00000024693;UniProtKB:Q9UMX3;ensembl:ENSP00000314132 10090 Mus musculus UniProt 20260724 UniProtKB:Q3THY9!447254351 UniProtKB:Q3THY9 Bcl10 B-cell lymphoma/leukemia 10 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033238 10090 Mus musculus InterPro 20260727 UniProtKB:Q3TJF3!327752286 UniProtKB:Q3TJF3 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3TNR7!208240311 UniProtKB:Q3TNR7 Bcl2l13 Bcl-2 Bcl-2 homology region 1-3 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR042398 10090 Mus musculus InterPro 20260727 UniProtKB:Q3TPX4!58893279 UniProtKB:Q3TPX4 Exoc5 Exocyst complex component 5 acts_upstream_of_or_within_negative_effect GO:0006915 apoptotic process IMP ECO:0000315 PMID:26040895 MGI:MGI:2665300;MGI:MGI:4455411 10090 Mus musculus MGI 20220920 UniProtKB:Q3TR08!297896145 UniProtKB:Q3TR08 Fndc4 Fibronectin type III domain-containing protein 4 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:39197598 10090 Mus musculus MGI 20260225 UniProtKB:Q3TU15!417382146 UniProtKB:Q3TU15 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3TVL4!58893517 UniProtKB:Q3TVL4 Mdm2 E3 ubiquitin-protein ligase Mdm2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3TVW5!268022186 UniProtKB:Q3TVW5 Tchp Trichoplein keratin filament-binding protein involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q9BT92 10090 Mus musculus UniProt 20101108 UniProtKB:Q3TVW5!268022187 UniProtKB:Q3TVW5 Tchp Trichoplein keratin filament-binding protein involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN001580733;UniProtKB:Q9BT92 10090 Mus musculus GO_Central 20190409 UniProtKB:Q3TVW5!268022188 UniProtKB:Q3TVW5 Tchp Trichoplein keratin filament-binding protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9BT92 10090 Mus musculus GO_Central 20260528 UniProtKB:Q3U001!29004724 UniProtKB:Q3U001 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:Q3U0V2!29004799 UniProtKB:Q3U0V2 Tradd Tumor necrosis factor receptor type 1-associated DEATH domain protein acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q3U0Y6!118637443 UniProtKB:Q3U0Y6 Il1a Interleukin-1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3U1J1!178353475 UniProtKB:Q3U1J1 Tfpt TCF3 fusion partner homolog involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033555 10090 Mus musculus InterPro 20260727 UniProtKB:Q3U1J1!178353476 UniProtKB:Q3U1J1 Tfpt TCF3 fusion partner homolog involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q9JMG6 10090 Mus musculus UniProt 20110120 UniProtKB:Q3U1J1!178353477 UniProtKB:Q3U1J1 Tfpt TCF3 fusion partner homolog involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:620839 10090 Mus musculus GO_Central 20260528 UniProtKB:Q3U1W7!238128398 UniProtKB:Q3U1W7 Notch2 Notch receptor 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022336 10090 Mus musculus InterPro 20260727 UniProtKB:Q3U3R1!238128532 UniProtKB:Q3U3R1 Tnfrsf9 TNFR-Cys domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR020413 10090 Mus musculus InterPro 20260727 UniProtKB:Q3U5C7!447255399 UniProtKB:Q3U5C7 Prickle1 Prickle-like protein 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:23913870 MGI:MGI:4941929 10090 Mus musculus MGI 20220830 UniProtKB:Q3U607!417382832 UniProtKB:Q3U607 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 UniProtKB:Q14790;ensembl:ENSP00000501268;InterPro:IPR033170 10090 Mus musculus UniProt 20260727 UniProtKB:Q3U7M4!268022958 UniProtKB:Q3U7M4 Myd88 Myeloid differentiation primary response protein MyD88 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q99836;ensembl:ENSP00000498360 10090 Mus musculus Ensembl 20260724 UniProtKB:Q3U9H3!417383031 UniProtKB:Q3U9H3 Bad Uncharacterized protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 UniProtKB:Q92934;ensembl:ENSP00000309103;InterPro:IPR018868 10090 Mus musculus UniProt 20260727 UniProtKB:Q3UF84!327754029 UniProtKB:Q3UF84 Ppp1r13b Apoptosis-stimulating of p53 protein 2-like RA domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028319 10090 Mus musculus InterPro 20260727 UniProtKB:Q3UGC5!29005881 UniProtKB:Q3UGC5 Bcl2l13 Bcl-2 Bcl-2 homology region 1-3 domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR042398 10090 Mus musculus InterPro 20260727 UniProtKB:Q3UGQ1!238129034 UniProtKB:Q3UGQ1 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q3UIA5!357625763 UniProtKB:Q3UIA5 Cul1 Cullin-1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3UMB0!208242366 UniProtKB:Q3UMB0 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q3UVH8!118639833 UniProtKB:Q3UVH8 Nkx3-1 Homeobox protein Nkx-3.1 involved_in GO:0006915 apoptotic process IEA ECO:0000366 GO_REF:0000108 GO:0008656 10090 Mus musculus GOC 20260727 UniProtKB:Q3UVI3!178355067 UniProtKB:Q3UVI3 Trp63 Tumor protein 63 (p63) involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q3UWE8!29007026 UniProtKB:Q3UWE8 Pawr PRKC apoptosis WT1 regulator protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR026117 10090 Mus musculus InterPro 20260727 UniProtKB:Q3UYN3!88748955 UniProtKB:Q3UYN3 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:Q3V4D3!208243582 UniProtKB:Q3V4D3 Cideb Lipid transferase CIDEB involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:Q4FJK5!477128589 UniProtKB:Q4FJK5 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q4FJQ4!327770399 UniProtKB:Q4FJQ4 Casp7 Casp7 protein involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P55210;ensembl:ENSP00000358324 10090 Mus musculus Ensembl 20260724 UniProtKB:Q4FK43!268039254 UniProtKB:Q4FK43 Emp1 Epithelial membrane protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P54849;ensembl:ENSP00000256951 10090 Mus musculus Ensembl 20260724 UniProtKB:Q4FK85!29022042 UniProtKB:Q4FK85 Casp8 Caspase-8 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033170 10090 Mus musculus InterPro 20260727 UniProtKB:Q52KR3!148542538 UniProtKB:Q52KR3 Prune2 Protein prune homolog 2 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN000251507;UniProtKB:Q7Z465 10090 Mus musculus GO_Central 20230110 UniProtKB:Q53YN4!29043948 UniProtKB:Q53YN4 Prkcd Protein kinase C delta type involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q05655;ensembl:ENSP00000331602 10090 Mus musculus Ensembl 20260724 UniProtKB:Q542N5!417420602 UniProtKB:Q542N5 Bcl2l11 Bcl-2-like protein 11 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000273842 10090 Mus musculus UniProt 20260727 UniProtKB:Q544E9!208280438 UniProtKB:Q544E9 Fasl Tumor necrosis factor ligand superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028326 10090 Mus musculus InterPro 20260727 UniProtKB:Q544I2!417420840 UniProtKB:Q544I2 Il2ra Interleukin-2 receptor subunit alpha involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q544Z6!118676103 UniProtKB:Q544Z6 Bax Apoptosis regulator BAX involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q07812;ensembl:ENSP00000263262 10090 Mus musculus Ensembl 20260724 UniProtKB:Q546I3!417421010 UniProtKB:Q546I3 Ppard Peroxisome proliferator activated receptor beta/delta involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q03181;ensembl:ENSP00000353916 10090 Mus musculus Ensembl 20260724 UniProtKB:Q547H1!297934859 UniProtKB:Q547H1 Ripk2 Receptor-interacting serine/threonine-protein kinase 2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:O43353;ensembl:ENSP00000220751 10090 Mus musculus Ensembl 20260724 UniProtKB:Q548I4!88785630 UniProtKB:Q548I4 Emp2 Epithelial membrane protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P54851;ensembl:ENSP00000352540 10090 Mus musculus Ensembl 20260724 UniProtKB:Q549C9!357663156 UniProtKB:Q549C9 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q569E5!88789424 UniProtKB:Q569E5 Trp63 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q569X0!268063953 UniProtKB:Q569X0 Mdm2 E3 ubiquitin-protein ligase Mdm2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q5CZX0!417435685 UniProtKB:Q5CZX0 Trp63 Tumor protein 63 (p63) involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q5DU30!29060578 UniProtKB:Q5DU30 Apaf1 Apoptotic protease-activating factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q5F283!417439365 UniProtKB:Q5F283 Plscr3 Phospholipid scramblase involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9NRY6;ensembl:ENSP00000483743 10090 Mus musculus Ensembl 20260724 UniProtKB:Q5F2A0!268078749 UniProtKB:Q5F2A0 Tnfsf12 Tumor necrosis factor ligand superfamily member 12 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q5HZH3!387550792 UniProtKB:Q5HZH3 Bcl2l1 Bcl-2-like protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:Q5NBU8!88818369 UniProtKB:Q5NBU8 Xaf1 XIAP-associated factor 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR041386 10090 Mus musculus InterPro 20260727 UniProtKB:Q5SQX6!477190038 UniProtKB:Q5SQX6 Cyfip2 Cytoplasmic FMR1-interacting protein 2 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q96F07 10090 Mus musculus UniProt 20070411 UniProtKB:Q5SQX6!477190039 UniProtKB:Q5SQX6 Cyfip2 Cytoplasmic FMR1-interacting protein 2 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN002638922;UniProtKB:Q96F07 10090 Mus musculus GO_Central 20200317 UniProtKB:Q5SQX6!477190040 UniProtKB:Q5SQX6 Cyfip2 Cytoplasmic FMR1-interacting protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q96F07;ensembl:ENSP00000479968 10090 Mus musculus Ensembl 20260724 UniProtKB:Q5SQX6!477190041 UniProtKB:Q5SQX6 Cyfip2 Cytoplasmic FMR1-interacting protein 2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q96F07 10090 Mus musculus GO_Central 20260702 UniProtKB:Q5SX13!268100435 UniProtKB:Q5SX13 Irf1 Interferon regulatory factor involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P10914;ensembl:ENSP00000245414 10090 Mus musculus Ensembl 20260724 UniProtKB:Q5SXS3!88826995 UniProtKB:Q5SXS3 Pmp22 Peripheral myelin protein 22 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q01453;ensembl:ENSP00000308937 10090 Mus musculus Ensembl 20260724 UniProtKB:Q5U4C7!88828083 UniProtKB:Q5U4C7 Gramd4 GRAM domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR037847 10090 Mus musculus InterPro 20260727 UniProtKB:Q60707!268111723 UniProtKB:Q60707 Tbx2 T-box transcription factor TBX2 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:33795231 10090 Mus musculus UniProt 20210831 UniProtKB:Q60855!268112070 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q13546 10090 Mus musculus UniProt 20131028 UniProtKB:Q60855!268112071 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q13546;ensembl:ENSP00000259808 10090 Mus musculus Ensembl 20260724 UniProtKB:Q60855!268112072 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q13546 10090 Mus musculus GO_Central 20260702 UniProtKB:Q60855!268112073 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:28842570 10090 Mus musculus UniProt 20191009 UniProtKB:Q60855!268112074 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:29440439 10090 Mus musculus UniProt 20191014 UniProtKB:Q60855!268112075 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:30867408 10090 Mus musculus UniProt 20191014 UniProtKB:Q60855!268112076 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:31511692 10090 Mus musculus UniProt 20191014 UniProtKB:Q60855!268112077 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:31519886 10090 Mus musculus UniProt 20191014 UniProtKB:Q60855!268112078 UniProtKB:Q60855 Ripk1 Receptor-interacting serine/threonine-protein kinase 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:31519887 10090 Mus musculus UniProt 20191014 UniProtKB:Q60932!58983358 UniProtKB:Q60932 Vdac1 Non-selective voltage-gated ion channel VDAC1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P21796 10090 Mus musculus UniProt 20150814 UniProtKB:Q60932!58983359 UniProtKB:Q60932 Vdac1 Non-selective voltage-gated ion channel VDAC1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P21796;ensembl:ENSP00000265333 10090 Mus musculus Ensembl 20260724 UniProtKB:Q60932!58983360 UniProtKB:Q60932 Vdac1 Non-selective voltage-gated ion channel VDAC1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P21796 10090 Mus musculus GO_Central 20260702 UniProtKB:Q60953!208333061 UniProtKB:Q60953 Pml Protein PML involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P29590 10090 Mus musculus GO_Central 20260702 UniProtKB:Q61038!238219086 UniProtKB:Q61038 Gpr65 G protein-coupled receptor 65 involved_in GO:0006915 apoptotic process TAS ECO:0000304 PMID:15618224 10090 Mus musculus BHF-UCL 20091124 UniProtKB:Q61160!477202390 UniProtKB:Q61160 Fadd FAS-associated death domain protein involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q13158 10090 Mus musculus UniProt 20131106 UniProtKB:Q61160!477202391 UniProtKB:Q61160 Fadd FAS-associated death domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q13158;ensembl:ENSP00000301838 10090 Mus musculus Ensembl 20260724 UniProtKB:Q61160!477202392 UniProtKB:Q61160 Fadd FAS-associated death domain protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q13158 10090 Mus musculus GO_Central 20260702 UniProtKB:Q61337!447347331 UniProtKB:Q61337 Bad Bcl2-associated agonist of cell death involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR018868 10090 Mus musculus InterPro 20260727 UniProtKB:Q61337!447347332 UniProtKB:Q61337 Bad Bcl2-associated agonist of cell death involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q92934 10090 Mus musculus GO_Central 20260702 UniProtKB:Q61743!178447862 UniProtKB:Q61743 Kcnj11 ATP-sensitive inward rectifier potassium channel 11 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:24498880 MGI:MGI:2178821 10090 Mus musculus MGI 20230417 UniProtKB:Q61846!238219916 UniProtKB:Q61846 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q14680 10090 Mus musculus UniProt 20110818 UniProtKB:Q61846!238219917 UniProtKB:Q61846 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q14680 10090 Mus musculus GO_Central 20260611 UniProtKB:Q61846!238219918 UniProtKB:Q61846 Melk Maternal embryonic leucine zipper kinase involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:Q14680;ensembl:ENSP00000298048 10090 Mus musculus UniProt 20260724 UniProtKB:Q62048!447348153 UniProtKB:Q62048 Pea15 Astrocytic phosphoprotein PEA-15 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q62092!387582243 UniProtKB:Q62092 Nsg1 Neuronal vesicle trafficking-associated protein 1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P42857 10090 Mus musculus UniProt 20171020 UniProtKB:Q62092!387582244 UniProtKB:Q62092 Nsg1 Neuronal vesicle trafficking-associated protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P42857;ensembl:ENSP00000480081 10090 Mus musculus Ensembl 20260724 UniProtKB:Q62092!387582245 UniProtKB:Q62092 Nsg1 Neuronal vesicle trafficking-associated protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P42857 10090 Mus musculus GO_Central 20260611 UniProtKB:Q62161!327844658 UniProtKB:Q62161 Il1a Interleukin-1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q62312!357717810 UniProtKB:Q62312 Tgfbr2 TGF-beta receptor type-2 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P37173;ensembl:ENSP00000295754 10090 Mus musculus Ensembl 20260724 UniProtKB:Q62312!357717811 UniProtKB:Q62312 Tgfbr2 TGF-beta receptor type-2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P37173 10090 Mus musculus GO_Central 20260611 UniProtKB:Q62415!88840709 UniProtKB:Q62415 Ppp1r13b Apoptosis-stimulating of p53 protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028319 10090 Mus musculus InterPro 20260727 UniProtKB:Q63934!58987716 UniProtKB:Q63934 Pou4f2 POU domain, class 4, transcription factor 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q63955!387585223 UniProtKB:Q63955 Pou4f3 POU domain, class 4, transcription factor 3 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q64221!178451928 UniProtKB:Q64221 Nhlh2 Helix-loop-helix protein 2 acts_upstream_of_or_within_positive_effect GO:0006915 apoptotic process IGI ECO:0000316 PMID:17573818 UniProtKB:Q02576 10090 Mus musculus UniProt 20201111 UniProtKB:Q64364!208340671 UniProtKB:Q64364 Cdkn2a Tumor suppressor ARF involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR010868 10090 Mus musculus InterPro 20260727 UniProtKB:Q64451!297993498 UniProtKB:Q64451 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q64FM2!357722795 UniProtKB:Q64FM2 Pou4f1 POU domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q6IQY5!447381297 UniProtKB:Q6IQY5 Cep70 Centrosomal protein of 70 kDa acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:33980814 10090 Mus musculus MGI 20250910 UniProtKB:Q6NTH7!29139794 UniProtKB:Q6NTH7 Bcl2 Apoptosis regulator Bcl-2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:Q6P549!59027549 UniProtKB:Q6P549 Inppl1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:28878342 10090 Mus musculus MGI 20231115 UniProtKB:Q6P549!59027550 UniProtKB:Q6P549 Inppl1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:28878342 MGI:MGI:1330281 10090 Mus musculus MGI 20231115 UniProtKB:Q6PCM9!357761603 UniProtKB:Q6PCM9 Notch2 Notch C-terminal domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022336 10090 Mus musculus InterPro 20260727 UniProtKB:Q6PFY1!447390752 UniProtKB:Q6PFY1 Fchsd1 F-BAR and double SH3 domains protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:34168078 10090 Mus musculus MGI 20240924 UniProtKB:Q6QD59!178492452 UniProtKB:Q6QD59 Bnip1 Vesicle transport protein SEC20 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:7954800 UniProtKB:Q12981 10090 Mus musculus MGI 20110609 UniProtKB:Q6S5L9!447394951 UniProtKB:Q6S5L9 Shc4 SHC-transforming protein 4 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:22948967 10090 Mus musculus MGI 20140218 UniProtKB:Q6TDG9!387631473 UniProtKB:Q6TDG9 Trp53 p53 tetramerisation domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q78NA5!327916107 UniProtKB:Q78NA5 Pou4f1 POU domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q7TMV9!477286848 UniProtKB:Q7TMV9 Fasl Tumor necrosis factor ligand superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028326 10090 Mus musculus InterPro 20260727 UniProtKB:Q7TPS3!88928185 UniProtKB:Q7TPS3 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:Q7TS81!178533772 UniProtKB:Q7TS81 Dffb DNA fragmentation factor subunit beta involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:Q80SW1!417569707 UniProtKB:Q80SW1 Ahcyl1 S-adenosylhomocysteine hydrolase-like protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O43865 10090 Mus musculus GO_Central 20260528 UniProtKB:Q80TA9!29197192 UniProtKB:Q80TA9 Epg5 Ectopic P granules protein 5 homolog acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:27715390 10090 Mus musculus MGI 20240429 UniProtKB:Q80VR5!208438313 UniProtKB:Q80VR5 Apaf1 CARD domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q80YE4!387680812 UniProtKB:Q80YE4 Aatk Serine/threonine-protein kinase LMTK1 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:9444961 10090 Mus musculus MGI 20010605 UniProtKB:Q80YE7!208438704 UniProtKB:Q80YE7 Dapk1 Death-associated protein kinase 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:P53355 10090 Mus musculus MGI 20120105 UniProtKB:Q80YE7!208438733 UniProtKB:Q80YE7 Dapk1 Death-associated protein kinase 1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P53355;ensembl:ENSP00000386135 10090 Mus musculus Ensembl 20260724 UniProtKB:Q80YE7!208438734 UniProtKB:Q80YE7 Dapk1 Death-associated protein kinase 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P53355 10090 Mus musculus GO_Central 20260702 UniProtKB:Q80Z19!29198117 UniProtKB:Q80Z19 Muc2 Mucin-2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:11872843 MGI:MGI:2183923 10090 Mus musculus MGI 20030509 UniProtKB:Q80ZA1!327944757 UniProtKB:Q80ZA1 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q80ZA2!298089406 UniProtKB:Q80ZA2 Pou4f1 POU domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q8BG47!477322202 UniProtKB:Q8BG47 Rnf152 E3 ubiquitin-protein ligase RNF152 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033609 10090 Mus musculus InterPro 20260727 UniProtKB:Q8BG48!387701774 UniProtKB:Q8BG48 Stk17b Serine/threonine-protein kinase 17B involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:620457 10090 Mus musculus GO_Central 20260702 UniProtKB:Q8BG48!387701775 UniProtKB:Q8BG48 Stk17b Serine/threonine-protein kinase 17B involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q91XS8;ensembl:ENSRNOP00000016857 10090 Mus musculus Ensembl 20260724 UniProtKB:Q8BH31!118850042 UniProtKB:Q8BH31 Mfsd8 Major facilitator superfamily domain-containing protein 8 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:35087090 10090 Mus musculus MGI 20240604 UniProtKB:Q8BHE3!148719953 UniProtKB:Q8BHE3 Atcay Caytaxin involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN000251507;UniProtKB:Q7Z465 10090 Mus musculus GO_Central 20230110 UniProtKB:Q8BK06!477322998 UniProtKB:Q8BK06 Fbxo9 F-box only protein 9 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9UK97 10090 Mus musculus GO_Central 20250828 UniProtKB:Q8BK75!118850459 UniProtKB:Q8BK75 Elp6 Elongator complex protein 6 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:27715390 10090 Mus musculus MGI 20240904 UniProtKB:Q8BP66!477323310 UniProtKB:Q8BP66 Dffb DNA fragmentation factor subunit beta involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:Q8BQK4!148720745 UniProtKB:Q8BQK4 Bcl2 Apoptosis regulator Bcl-2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:Q8BRM9!357842357 UniProtKB:Q8BRM9 Dedd2 Uncharacterized protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:Q8BUN5!447471561 UniProtKB:Q8BUN5 Smad3 SMAD family member 3 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:19679673 10090 Mus musculus MGI 20231107 UniProtKB:Q8BVB0!477323640 UniProtKB:Q8BVB0 Pak5 non-specific serine/threonine protein kinase involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028754 10090 Mus musculus InterPro 20260727 UniProtKB:Q8BX43!327968871 UniProtKB:Q8BX43 Relt Tumor necrosis factor receptor superfamily member 19L involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN002934004;UniProtKB:Q969Z4 10090 Mus musculus GO_Central 20200206 UniProtKB:Q8BX43!327968872 UniProtKB:Q8BX43 Relt Tumor necrosis factor receptor superfamily member 19L involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q969Z4;ensembl:ENSP00000064780 10090 Mus musculus Ensembl 20260724 UniProtKB:Q8BX43!327968873 UniProtKB:Q8BX43 Relt Tumor necrosis factor receptor superfamily member 19L involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q969Z4 10090 Mus musculus GO_Central 20260723 UniProtKB:Q8BXG3!327968915 UniProtKB:Q8BXG3 Ift57 Intraflagellar transport protein 57 homolog acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:11788820 UniProtKB:Q9NWB7 10090 Mus musculus MGI 20030627 UniProtKB:Q8C015!178570065 UniProtKB:Q8C015 Pak5 Serine/threonine-protein kinase PAK 5 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028754 10090 Mus musculus InterPro 20260727 UniProtKB:Q8C2H9!238343905 UniProtKB:Q8C2H9 Il2ra Interleukin-2 receptor subunit alpha involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q8C2Q3!357843146 UniProtKB:Q8C2Q3 Rbm14 RNA-binding protein 14 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:31794640 MGI:MGI:6455488 10090 Mus musculus MGI 20230920 UniProtKB:Q8C3Q0!298113609 UniProtKB:Q8C3Q0 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q8C3Q9!88965764 UniProtKB:Q8C3Q9 Casp9 Caspase-9 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:12847083 10090 Mus musculus MGI 20081229 UniProtKB:Q8C3Q9!88965765 UniProtKB:Q8C3Q9 Casp9 Caspase-9 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16469926 10090 Mus musculus MGI 20150325 UniProtKB:Q8C3Q9!88965766 UniProtKB:Q8C3Q9 Casp9 Caspase-9 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:17901126 10090 Mus musculus MGI 20110309 UniProtKB:Q8C3Q9!88965794 UniProtKB:Q8C3Q9 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0010501;FB:FBgn0019972;FB:FBgn0020381;FB:FBgn0028381;FB:FBgn0033051;FB:FBgn0033659;MGI:MGI:107739;MGI:MGI:109383;MGI:MGI:1261423;MGI:MGI:1277950;MGI:MGI:1312922;MGI:MGI:97295;PANTHER:PTN000047947;RGD:2275;RGD:61867;RGD:620944;RGD:621758;UniProtKB:A0A1D5PPP7;UniProtKB:O15519;UniProtKB:P42574;UniProtKB:P42575;UniProtKB:P49662;UniProtKB:P55210;UniProtKB:P55211;UniProtKB:P55212;UniProtKB:Q14790;UniProtKB:Q8MKI5;WB:WBGene00000417;ZFIN:ZDB-GENE-011210-1;ZFIN:ZDB-GENE-030825-3 10090 Mus musculus GO_Central 20251218 UniProtKB:Q8C3Q9!88965795 UniProtKB:Q8C3Q9 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P55211 10090 Mus musculus GO_Central 20260723 UniProtKB:Q8C3Q9!88965796 UniProtKB:Q8C3Q9 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:P55211;ensembl:ENSP00000330237 10090 Mus musculus UniProt 20260724 UniProtKB:Q8C3R1!357843204 UniProtKB:Q8C3R1 Brat1 Integrator complex assembly factor BRAT1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q6PJG6 10090 Mus musculus UniProt 20150704 UniProtKB:Q8C3R1!357843205 UniProtKB:Q8C3R1 Brat1 Integrator complex assembly factor BRAT1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q6PJG6;ensembl:ENSP00000339637 10090 Mus musculus Ensembl 20260724 UniProtKB:Q8C3R1!357843206 UniProtKB:Q8C3R1 Brat1 Integrator complex assembly factor BRAT1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q6PJG6 10090 Mus musculus GO_Central 20260723 UniProtKB:Q8C4X7!59109141 UniProtKB:Q8C4X7 Minar2 Major intrinsically disordered NOTCH2-binding receptor 1-like homolog acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:35727972 10090 Mus musculus MGI 20240401 UniProtKB:Q8C526!298113701 UniProtKB:Q8C526 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q8C535!298113710 UniProtKB:Q8C535 Dffa CIDE-N domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:Q8C5N5!477324593 UniProtKB:Q8C5N5 Pdcd2l uS5 assembly chaperone PDCD2L involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN000958854;ZFIN:ZDB-GENE-040426-967 10090 Mus musculus GO_Central 20220208 UniProtKB:Q8CA98!208462886 UniProtKB:Q8CA98 Dffa CIDE-N domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 InterPro:IPR003508;UniRule:UR000416040 10090 Mus musculus UniProt 20260727 UniProtKB:Q8CB44!59109517 UniProtKB:Q8CB44 Gramd4 GRAM domain-containing protein 4 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR037847 10090 Mus musculus InterPro 20260727 UniProtKB:Q8CD57!298114414 UniProtKB:Q8CD57 Fadd FAS-associated death domain protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000273310 10090 Mus musculus UniProt 20260727 UniProtKB:Q8CFV9!88966865 UniProtKB:Q8CFV9 Rfk Riboflavin kinase acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:Q969G6 10090 Mus musculus MGI 20131209 UniProtKB:Q8CGY8!59110309 UniProtKB:Q8CGY8 Ogt UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:O15294 10090 Mus musculus UniProt 20111216 UniProtKB:Q8CGY8!59110310 UniProtKB:Q8CGY8 Ogt UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:O15294;ensembl:ENSP00000362824 10090 Mus musculus Ensembl 20260724 UniProtKB:Q8CGY8!59110311 UniProtKB:Q8CGY8 Ogt UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O15294 10090 Mus musculus GO_Central 20260723 UniProtKB:Q8CHK4!447474536 UniProtKB:Q8CHK4 Kat5 Histone acetyltransferase KAT5 involved_in GO:0006915 apoptotic process IDA ECO:0000314 PMID:30655546 10090 Mus musculus MGI 20211207 UniProtKB:Q8CI61!268240028 UniProtKB:Q8CI61 Bag4 BAG family molecular chaperone regulator 4 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q8K057!298130738 UniProtKB:Q8K057 Ift80 Intraflagellar transport protein 80 homolog acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:32227389 10090 Mus musculus MGI 20240327 UniProtKB:Q8K0H5!268255412 UniProtKB:Q8K0H5 Taf10 Transcription initiation factor TFIID subunit 10 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:10469660 10090 Mus musculus MGI 20110425 UniProtKB:Q8K223!29236749 UniProtKB:Q8K223 Ercc2 General transcription and DNA repair factor IIH helicase subunit XPD involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P18074 10090 Mus musculus UniProt 20041006 UniProtKB:Q8K409!327986878 UniProtKB:Q8K409 Polb DNA polymerase beta acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:24388753 MGI:MGI:5427084 10090 Mus musculus MGI 20150211 UniProtKB:Q8K4B2!88984102 UniProtKB:Q8K4B2 Irak3 Interleukin-1 receptor-associated kinase 3 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q8QZV0!327996994 UniProtKB:Q8QZV0 Dedd2 DNA-binding death effector domain-containing protein 2 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q8QZV0!327996996 UniProtKB:Q8QZV0 Dedd2 DNA-binding death effector domain-containing protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:Q8R1D8!88995682 UniProtKB:Q8R1D8 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:Q8R3N6!208490226 UniProtKB:Q8R3N6 Thoc1 THO complex subunit 1 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q8VD12!298151014 UniProtKB:Q8VD12 Znf385a Zinc finger protein 385A involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:17719541 10090 Mus musculus UniProt 20130522 UniProtKB:Q8VD75!417630323 UniProtKB:Q8VD75 Hip1 Huntingtin-interacting protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:11788820 UniProtKB:O00291 10090 Mus musculus MGI 20060111 UniProtKB:Q8VDH1!238379709 UniProtKB:Q8VDH1 Fbxo21 F-box only protein 21 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:35987460 10090 Mus musculus MGI 20240917 UniProtKB:Q8VE73!29258449 UniProtKB:Q8VE73 Cul7 Cullin-7 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q8VEB2!89005140 UniProtKB:Q8VEB2 Sav1 Protein salvador homolog 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR030030 10090 Mus musculus InterPro 20260727 UniProtKB:Q8WUR0!118892202 UniProtKB:Q8WUR0 Q8WUR0 Protein C19orf12 homolog involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9NSK7;ensembl:ENSP00000313332 10090 Mus musculus Ensembl 20260724 UniProtKB:Q8WUR0!118892203 UniProtKB:Q8WUR0 Q8WUR0 Protein C19orf12 homolog involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9NSK7 10090 Mus musculus GO_Central 20260723 UniProtKB:Q91WM6!417645356 UniProtKB:Q91WM6 Eva1a Protein eva-1 homolog A acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:28151473 10090 Mus musculus MGI 20240904 UniProtKB:Q91X17!417645557 UniProtKB:Q91X17 Umod Uromodulin acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:29145399 10090 Mus musculus MGI 20200305 UniProtKB:Q91XC8!328021549 UniProtKB:Q91XC8 Dap Death-associated protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:P51397 10090 Mus musculus MGI 20120105 UniProtKB:Q91XH8!178621564 UniProtKB:Q91XH8 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q91Y11!178621722 UniProtKB:Q91Y11 Pcdha9 Protocadherin alpha-9 acts_upstream_of_or_within GO:0006915 apoptotic process ISA ECO:0000247 PMID:29477871 UniProtKB:Q9Y5H5 10090 Mus musculus MGI 20240313 UniProtKB:Q91Y11!178621723 UniProtKB:Q91Y11 Pcdha9 Protocadherin alpha-9 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:29477871 UniProtKB:Q9Y5H5 10090 Mus musculus MGI 20240409 UniProtKB:Q91ZE9!148774061 UniProtKB:Q91ZE9 Bmf Bcl-2-modifying factor involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028192 10090 Mus musculus InterPro 20260727 UniProtKB:Q91ZI8!29273507 UniProtKB:Q91ZI8 Dio3 Thyroxine 5-deiodinase acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:20203194 MGI:MGI:2664293 10090 Mus musculus MGI 20161026 UniProtKB:Q91ZX7!148774203 UniProtKB:Q91ZX7 Lrp1 Prolow-density lipoprotein receptor-related protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:32546759 10090 Mus musculus MGI 20240320 UniProtKB:Q921K2!238395738 UniProtKB:Q921K2 Parp1 Poly [ADP-ribose] polymerase involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P09874;ensembl:ENSP00000355759 10090 Mus musculus Ensembl 20260724 UniProtKB:Q922B6!148774824 UniProtKB:Q922B6 Traf7 E3 ubiquitin-protein ligase TRAF7 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:15001576 UniProtKB:Q6Q0C0 10090 Mus musculus MGI 20060120 UniProtKB:Q922B6!148774837 UniProtKB:Q922B6 Traf7 E3 ubiquitin-protein ligase TRAF7 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN008571510;UniProtKB:Q6Q0C0 10090 Mus musculus GO_Central 20240528 UniProtKB:Q922E6!148774877 UniProtKB:Q922E6 Fastkd2 FAST kinase domain-containing protein 2, mitochondrial involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q9NYY8 10090 Mus musculus UniProt 20201223 UniProtKB:Q922E6!148774878 UniProtKB:Q922E6 Fastkd2 FAST kinase domain-containing protein 2, mitochondrial involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9NYY8;ensembl:ENSP00000385990 10090 Mus musculus Ensembl 20260724 UniProtKB:Q922E6!148774879 UniProtKB:Q922E6 Fastkd2 FAST kinase domain-containing protein 2, mitochondrial involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9NYY8 10090 Mus musculus GO_Central 20260723 UniProtKB:Q925B0!178623123 UniProtKB:Q925B0 Pawr PRKC apoptosis WT1 regulator protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR026117 10090 Mus musculus InterPro 20260727 UniProtKB:Q925B0!178623124 UniProtKB:Q925B0 Pawr PRKC apoptosis WT1 regulator protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000096 RGD:69065 10090 Mus musculus GO_Central 20260723 UniProtKB:Q925E2!89021751 UniProtKB:Q925E2 Q925E2 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q99JU7!208532784 UniProtKB:Q99JU7 Bnipl Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:Q7Z465 10090 Mus musculus MGI 20130715 UniProtKB:Q99JU7!208532786 UniProtKB:Q99JU7 Bnipl Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 PANTHER:PTN000251507;UniProtKB:Q7Z465 10090 Mus musculus GO_Central 20230110 UniProtKB:Q99JU7!208532787 UniProtKB:Q99JU7 Bnipl Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q7Z465 10090 Mus musculus GO_Central 20260723 UniProtKB:Q99JZ7!238412802 UniProtKB:Q99JZ7 Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:20418913 MGI:MGI:109583 10090 Mus musculus MGI 20230726 UniProtKB:Q99JZ7!238412803 UniProtKB:Q99JZ7 Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:22975324 10090 Mus musculus MGI 20230726 UniProtKB:Q99JZ7!238412804 UniProtKB:Q99JZ7 Errfi1 ERBB receptor feedback inhibitor 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:22975324 MGI:MGI:3639295 10090 Mus musculus MGI 20230726 UniProtKB:Q99KR7!268310701 UniProtKB:Q99KR7 Ppif Peptidyl-prolyl cis-trans isomerase F, mitochondrial acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:19293339 MGI:MGI:88459 10090 Mus musculus MGI 20230926 UniProtKB:Q99L97!447544084 UniProtKB:Q99L97 Bik Bik protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024579 10090 Mus musculus InterPro 20260727 UniProtKB:Q99M87!59179100 UniProtKB:Q99M87 Dnaja3 DnaJ homolog subfamily A member 3, mitochondrial acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:16327803 MGI:MGI:2182091|MGI:MGI:3040717 10090 Mus musculus MGI 20080515 UniProtKB:Q99ML1!89038760 UniProtKB:Q99ML1 Bbc3 Bcl-2-binding component 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q96PG8 10090 Mus musculus GO_Central 20260702 UniProtKB:Q99ML1!89038761 UniProtKB:Q99ML1 Bbc3 Bcl-2-binding component 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9BXH1 10090 Mus musculus GO_Central 20260723 UniProtKB:Q99N43!447544606 UniProtKB:Q99N43 Kremen1 Kremen protein 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:26206087 10090 Mus musculus UniProt 20170307 UniProtKB:Q99PH8!59179585 UniProtKB:Q99PH8 Fasl Tumor necrosis factor ligand superfamily member 6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR028326 10090 Mus musculus InterPro 20260727 UniProtKB:Q9CPT0!417672426 UniProtKB:Q9CPT0 Bcl2l14 Apoptosis facilitator Bcl-2-like protein 14 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q9CPT0!417672431 UniProtKB:Q9CPT0 Bcl2l14 Apoptosis facilitator Bcl-2-like protein 14 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9BZR8;ensembl:ENSP00000309132 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9CPT0!417672432 UniProtKB:Q9CPT0 Bcl2l14 Apoptosis facilitator Bcl-2-like protein 14 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9BZR8 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9CRB8!387784635 UniProtKB:Q9CRB8 Mtfp1 Mitochondrial fission process protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:30325740 10090 Mus musculus MGI 20191003 UniProtKB:Q9CRD4!328051169 UniProtKB:Q9CRD4 Dbndd2 Dysbindin domain-containing protein 2 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:18096156 10090 Mus musculus MGI 20240806 UniProtKB:Q9CRJ8!477403424 UniProtKB:Q9CRJ8 Tfpt INO80 complex subunit F domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033555 10090 Mus musculus InterPro 20260727 UniProtKB:Q9CWL8!357920707 UniProtKB:Q9CWL8 Ctnnbl1 Beta-catenin-like protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:12659813 UniProtKB:Q8WYA6 10090 Mus musculus MGI 20130715 UniProtKB:Q9CXN7!29300139 UniProtKB:Q9CXN7 Pbld2 Phenazine biosynthesis-like domain-containing protein 2 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q9DCG6 10090 Mus musculus UniProt 20250624 UniProtKB:Q9CXN7!29300140 UniProtKB:Q9CXN7 Pbld2 Phenazine biosynthesis-like domain-containing protein 2 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9CXN7!29300141 UniProtKB:Q9CXN7 Pbld2 Phenazine biosynthesis-like domain-containing protein 2 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P30039 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9D3F7!148801936 UniProtKB:Q9D3F7 Ddit4 DNA damage-inducible transcript 4 protein involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 FB:FBgn0036165;FB:FBgn0041094;MGI:MGI:1921997;PANTHER:PTN000280371 10090 Mus musculus GO_Central 20230602 UniProtKB:Q9D6A3!89047469 UniProtKB:Q9D6A3 Trp73 SAM domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q9DB75!477405100 UniProtKB:Q9DB75 Cdip1 Cell death-inducing p53-target protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:Q9H305 10090 Mus musculus MGI 20070906 UniProtKB:Q9DCG6!328053358 UniProtKB:Q9DCG6 Pbld1 Phenazine biosynthesis-like domain-containing protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9DCG6!328053359 UniProtKB:Q9DCG6 Pbld1 Phenazine biosynthesis-like domain-containing protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P30039 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9DCG6!328053360 UniProtKB:Q9DCG6 Pbld1 Phenazine biosynthesis-like domain-containing protein 1 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:39362857 10090 Mus musculus UniProt 20250620 UniProtKB:Q9EPB4!268323939 UniProtKB:Q9EPB4 Pycard Apoptosis-associated speck-like protein containing a CARD acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:11139337 UniProtKB:Q9ULZ3 10090 Mus musculus MGI 20050929 UniProtKB:Q9EPU5!59193753 UniProtKB:Q9EPU5 Tnfrsf21 Tumor necrosis factor receptor superfamily member 21 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:O75509;ensembl:ENSP00000296861 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9EPU5!59193754 UniProtKB:Q9EPU5 Tnfrsf21 Tumor necrosis factor receptor superfamily member 21 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O75509 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9ER40!178655846 UniProtKB:Q9ER40 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q9ER88!268324580 UniProtKB:Q9ER88 Dap3 Small ribosomal subunit protein mS29 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR008092 10090 Mus musculus InterPro 20260727 UniProtKB:Q9ERH6!268324598 UniProtKB:Q9ERH6 Moap1 Modulator of apoptosis 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:11060313 UniProtKB:Q96BY2 10090 Mus musculus MGI 20080612 UniProtKB:Q9ERH6!268324599 UniProtKB:Q9ERH6 Moap1 Modulator of apoptosis 1 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q9ERV7!178656064 UniProtKB:Q9ERV7 Pidd1 p53-induced death domain-containing protein 1 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 MGI:MGI:1889507;PANTHER:PTN008161237;UniProtKB:Q9HB75 10090 Mus musculus GO_Central 20240418 UniProtKB:Q9ERV7!178656065 UniProtKB:Q9ERV7 Pidd1 p53-induced death domain-containing protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:C0HMD6 10090 Mus musculus GO_Central 20260423 UniProtKB:Q9ERV7!178656066 UniProtKB:Q9ERV7 Pidd1 p53-induced death domain-containing protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9HB75 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9ERV7!178656067 UniProtKB:Q9ERV7 Pidd1 p53-induced death domain-containing protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000501 GO_REF:0000120 ARBA:ARBA00027755;UniProtKB:Q9HB75;ensembl:ENSP00000337797;InterPro:IPR019502 10090 Mus musculus UniProt 20260727 UniProtKB:Q9JI11!148820323 UniProtKB:Q9JI11 Stk4 Serine/threonine-protein kinase 4 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q13043 10090 Mus musculus UniProt 20110904 UniProtKB:Q9JI11!148820324 UniProtKB:Q9JI11 Stk4 Serine/threonine-protein kinase 4 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q13043;ensembl:ENSP00000361892 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9JI11!148820325 UniProtKB:Q9JI11 Stk4 Serine/threonine-protein kinase 4 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q13043 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9JIQ3!59208264 UniProtKB:Q9JIQ3 Diablo Diablo IAP-binding mitochondrial protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR009062;InterPro:IPR015142 10090 Mus musculus InterPro 20260727 UniProtKB:Q9JIX8!148820553 UniProtKB:Q9JIX8 Acin1 Apoptotic chromatin condensation inducer in the nucleus acts_upstream_of_or_within GO:0006915 apoptotic process ISS ECO:0000250 PMID:10490026 10090 Mus musculus MGI 20010109 UniProtKB:Q9JIZ9!208561343 UniProtKB:Q9JIZ9 Plscr3 Phospholipid scramblase 3 involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 MGI:MGI:1917560;PANTHER:PTN008594829;UniProtKB:Q9NRY6 10090 Mus musculus GO_Central 20250618 UniProtKB:Q9JIZ9!208561344 UniProtKB:Q9JIZ9 Plscr3 Phospholipid scramblase 3 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q9NRY6;ensembl:ENSP00000483743 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9JIZ9!208561345 UniProtKB:Q9JIZ9 Plscr3 Phospholipid scramblase 3 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9NRY6 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9JIZ9!208561346 UniProtKB:Q9JIZ9 Plscr3 Phospholipid scramblase 3 involved_in GO:0006915 apoptotic process IMP ECO:0000315 PMID:21785166 10090 Mus musculus UniProt 20200518 UniProtKB:Q9JJ00!328070024 UniProtKB:Q9JJ00 Plscr1 Phospholipid scramblase 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O15162 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9JJP2!417693342 UniProtKB:Q9JJP2 Tp73 Tumor protein p73 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Q9JK48!328070435 UniProtKB:Q9JK48 Sh3glb1 Endophilin-B1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 PMID:11259440 UniProtKB:Q9Y371 10090 Mus musculus MGI 20010814 UniProtKB:Q9JLQ0!417694181 UniProtKB:Q9JLQ0 Cd2ap CD2-associated protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:14512504 MGI:MGI:2664945 10090 Mus musculus MGI 20231024 UniProtKB:Q9JLQ0!417694182 UniProtKB:Q9JLQ0 Cd2ap CD2-associated protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:15213232 MGI:MGI:2664945 10090 Mus musculus MGI 20231024 UniProtKB:Q9JLQ0!417694183 UniProtKB:Q9JLQ0 Cd2ap CD2-associated protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:19679673 10090 Mus musculus MGI 20231107 UniProtKB:Q9JLQ0!417694184 UniProtKB:Q9JLQ0 Cd2ap CD2-associated protein acts_upstream_of_or_within GO:0006915 apoptotic process IGI ECO:0000316 PMID:28878342 MGI:MGI:1333787 10090 Mus musculus MGI 20231115 UniProtKB:Q9JLV5!29321314 UniProtKB:Q9JLV5 Cul3 Cullin-3 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9JM54!29321650 UniProtKB:Q9JM54 Pmaip1 Phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000008 UniProtKB:Q13794 10090 Mus musculus MGI 20070906 UniProtKB:Q9JM54!29321668 UniProtKB:Q9JM54 Pmaip1 Phorbol-12-myristate-13-acetate-induced protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR024140 10090 Mus musculus InterPro 20260727 UniProtKB:Q9QWX2!59225363 UniProtKB:Q9QWX2 Bcl2l1 Bcl-2-like protein 1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000104 UniRule:UR000413482 10090 Mus musculus UniProt 20260727 UniProtKB:Q9QZM4!387823321 UniProtKB:Q9QZM4 Tnfrsf10b Tumor necrosis factor receptor superfamily member 10B acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q9R0G6!89083550 UniProtKB:Q9R0G6 Comp Cartilage oligomeric matrix protein acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:17588960 MGI:MGI:3758741 10090 Mus musculus MGI 20180912 UniProtKB:Q9R0S9!477441113 UniProtKB:Q9R0S9 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9R0T0!29338939 UniProtKB:Q9R0T0 Casp9 Caspase-9 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9R1E0!417712459 UniProtKB:Q9R1E0 Foxo1 Forkhead box protein O1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:Q12778 10090 Mus musculus UniProt 20200623 UniProtKB:Q9R1E0!417712460 UniProtKB:Q9R1E0 Foxo1 Forkhead box protein O1 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:Q12778;ensembl:ENSP00000368880 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9R1E0!417712461 UniProtKB:Q9R1E0 Foxo1 Forkhead box protein O1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q12778 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9WTR1!208598585 UniProtKB:Q9WTR1 Trpv2 Transient receptor potential cation channel subfamily V member 2 NOT|involved_in GO:0006915 apoptotic process IDA ECO:0000314 PMID:20357111 10090 Mus musculus DFLAT 20101015 UniProtKB:Q9WTX5!387842206 UniProtKB:Q9WTX5 Skp1 S-phase kinase-associated protein 1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P63208 10090 Mus musculus GO_Central 20250828 UniProtKB:Q9WTX6!417729888 UniProtKB:Q9WTX6 Cul1 Cullin-1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q13616 10090 Mus musculus GO_Central 20250828 UniProtKB:Q9WTX6!417729889 UniProtKB:Q9WTX6 Cul1 Cullin-1 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:10508527 MGI:MGI:2152042 10090 Mus musculus MGI 20020725 UniProtKB:Q9WTX6!417729922 UniProtKB:Q9WTX6 Cul1 Cullin-1 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000117 ARBA:ARBA00027755 10090 Mus musculus UniProt 20260727 UniProtKB:Q9WU78!447606725 UniProtKB:Q9WU78 Pdcd6ip Programmed cell death 6-interacting protein acts_upstream_of_or_within GO:0006915 apoptotic process TAS ECO:0000304 PMID:10858458 10090 Mus musculus MGI 20000810 UniProtKB:Q9WVG6!268375159 UniProtKB:Q9WVG6 Carm1 Histone-arginine methyltransferase CARM1 acts_upstream_of_or_within GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q86X55 10090 Mus musculus GO_Central 20250828 UniProtKB:Q9Z0F3!298254208 UniProtKB:Q9Z0F3 Bcl2l10 Bcl-2-like protein 10 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q9HD36 10090 Mus musculus GO_Central 20260528 UniProtKB:Q9Z0F4!447613397 UniProtKB:Q9Z0F4 Cib1 Calcium and integrin-binding protein 1 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:Q99828 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9Z0F4!447613398 UniProtKB:Q9Z0F4 Cib1 Calcium and integrin-binding protein 1 involved_in GO:0006915 apoptotic process ISS ECO:0000250 PMID:10366599 UniProtKB:Q99828 10090 Mus musculus HGNC-UCL 20060421 UniProtKB:Q9Z0H7!238484525 UniProtKB:Q9Z0H7 Bcl10 B-cell lymphoma/leukemia 10 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR033238 10090 Mus musculus InterPro 20260727 UniProtKB:Q9Z0X1!118995338 UniProtKB:Q9Z0X1 Aifm1 Apoptosis-inducing factor 1, mitochondrial involved_in GO:0006915 apoptotic process IBA ECO:0000318 GO_REF:0000033 MGI:MGI:1349419;PANTHER:PTN001115081;UniProtKB:O95831;WB:WBGene00006937 10090 Mus musculus GO_Central 20210623 UniProtKB:Q9Z0X1!118995339 UniProtKB:Q9Z0X1 Aifm1 Apoptosis-inducing factor 1, mitochondrial involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:O95831 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9Z1L3!357982464 UniProtKB:Q9Z1L3 Dedd Death effector domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR038856 10090 Mus musculus InterPro 20260727 UniProtKB:Q9Z1R2!298254704 UniProtKB:Q9Z1R2 Bag6 Large proline-rich protein BAG6 acts_upstream_of_or_within GO:0006915 apoptotic process RCA ECO:0000245 PMID:12819136 10090 Mus musculus MGI 20050811 UniProtKB:Q9Z1R2!298254744 UniProtKB:Q9Z1R2 Bag6 Large proline-rich protein BAG6 involved_in GO:0006915 apoptotic process ISS ECO:0000250 GO_REF:0000024 UniProtKB:P46379 10090 Mus musculus UniProt 20170228 UniProtKB:Q9Z1R2!298254745 UniProtKB:Q9Z1R2 Bag6 Large proline-rich protein BAG6 involved_in GO:0006915 apoptotic process IEA ECO:0000265 GO_REF:0000107 UniProtKB:P46379;ensembl:ENSP00000502941 10090 Mus musculus Ensembl 20260724 UniProtKB:Q9Z1R2!298254746 UniProtKB:Q9Z1R2 Bag6 Large proline-rich protein BAG6 involved_in GO:0006915 apoptotic process ISO ECO:0000266 GO_REF:0000119 UniProtKB:P46379 10090 Mus musculus GO_Central 20260723 UniProtKB:Q9Z265!148867089 UniProtKB:Q9Z265 Chek2 Serine/threonine-protein kinase Chk2 acts_upstream_of_or_within GO:0006915 apoptotic process IMP ECO:0000315 PMID:18614044 MGI:MGI:2386905 10090 Mus musculus MGI 20110511 UniProtKB:S4R1L5!29457955 UniProtKB:S4R1L5 Birc6 Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022103 10090 Mus musculus InterPro 20260727 UniProtKB:S4R2P8!268474566 UniProtKB:S4R2P8 Birc6 Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR022103 10090 Mus musculus InterPro 20260727 UniProtKB:W5VJU6!89509147 UniProtKB:W5VJU6 Trp53 Cellular tumor antigen p53 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Z4YK94!268870956 UniProtKB:Z4YK94 Trp73 Tumor protein p73 involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR002117 10090 Mus musculus InterPro 20260727 UniProtKB:Z4YN17!388344698 UniProtKB:Z4YN17 Xaf1 XIAP-associated factor 1 C-terminal domain-containing protein involved_in GO:0006915 apoptotic process IEA ECO:0000256 GO_REF:0000002 InterPro:IPR041386 10090 Mus musculus InterPro 20260727 RNAcentral:URS00006B11BD_10090!490554863 RNAcentral:URS00006B11BD_10090 Mus musculus (house mouse) microRNA mmu-mir-668 precursor Mus musculus (house mouse) microRNA mmu-mir-668 precursor acts_upstream_of_or_within_negative_effect GO:0006915 apoptotic process IMP ECO:0000315 PMID:30325740 10090 Mus musculus MGI 20191003 RNAcentral:URS00008E396E_10090!492959640 RNAcentral:URS00008E396E_10090 Mus musculus (mouse) predicted gene 12610 Mus musculus (mouse) predicted gene 12610 acts_upstream_of_or_within GO:0006915 apoptotic process IDA ECO:0000314 PMID:31674275 10090 Mus musculus MGI 20241022