summary:
  generated: '2026-10-21'
  n_pathways: 107
  coverage:
    NO_MODULE: 35
    MODULE_WITHOUT_ARABIDOPSIS: 21
    MODULE_WITHOUT_ARATH_GENES: 17
    MODULE_WITH_ARATH_GENES: 34
  n_kegg_ath_maps: 162
  n_kegg_maps_mapped: 69
  n_kegg_maps_out_of_scope: 32
  n_kegg_maps_not_assessed: 61
kegg_maps_not_assessed:
- ath00051 Fructose and mannose metabolism
- ath00232 Caffeine metabolism
- ath00240 Pyrimidine metabolism
- ath00280 Valine, leucine and isoleucine degradation
- ath00310 Lysine degradation
- ath00350 Tyrosine metabolism
- ath00360 Phenylalanine metabolism
- ath00410 beta-Alanine metabolism
- ath00430 Taurine and hypotaurine metabolism
- ath00440 Phosphonate and phosphinate metabolism
- ath00450 Selenocompound metabolism
- ath00460 Cyanoamino acid metabolism
- ath00470 D-Amino acid metabolism
- ath00510 N-Glycan biosynthesis
- ath00511 Other glycan degradation
- ath00513 Various types of N-glycan biosynthesis
- ath00514 Other types of O-glycan biosynthesis
- ath00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
- ath00565 Ether lipid metabolism
- ath00566 Sulfoquinovose metabolism
- ath00590 Arachidonic acid metabolism
- ath00591 Linoleic acid metabolism
- ath00620 Pyruvate metabolism
- ath00640 Propanoate metabolism
- ath00650 Butanoate metabolism
- ath00660 C5-Branched dibasic acid metabolism
- ath00785 Lipoic acid metabolism
- ath00901 Indole alkaloid biosynthesis
- ath00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
- ath00950 Isoquinoline alkaloid biosynthesis
- ath00960 Tropane, piperidine and pyridine alkaloid biosynthesis
- ath00965 Betalain biosynthesis
- ath00970 Aminoacyl-tRNA biosynthesis
- ath00999 Biosynthesis of various plant secondary metabolites
- ath02010 ABC transporters
- ath03008 Ribosome biogenesis in eukaryotes
- ath03010 Ribosome
- ath03013 Nucleocytoplasmic transport
- ath03015 mRNA surveillance pathway
- ath03018 RNA degradation
- ath03020 RNA polymerase
- ath03022 Basal transcription factors
- ath03030 DNA replication
- ath03040 Spliceosome
- ath03050 Proteasome
- ath03060 Protein export
- ath03082 ATP-dependent chromatin remodeling
- ath03410 Base excision repair
- ath03420 Nucleotide excision repair
- ath03430 Mismatch repair
- ath03440 Homologous recombination
- ath03450 Non-homologous end-joining
- ath03460 Fanconi anemia pathway
- ath04070 Phosphatidylinositol signaling system
- ath04120 Ubiquitin mediated proteolysis
- ath04122 Sulfur relay system
- ath04130 SNARE interactions in vesicular transport
- ath04144 Endocytosis
- ath04156 Integrated stress response (ISR) signaling pathway
- ath04814 Motor proteins
- ath04981 Folate transport and metabolism
pathways:
- name: Cold acclimation (ICE1-CBF)
  group: abiotic_stress
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named:
  - CBF1
  - ICE1
  arath_genes_outside_any_module:
  - CBF1
  notes: ICE1 sits in the stomatal lineage module as SCRM.
- name: Drought and osmotic signaling (DREB2)
  group: abiotic_stress
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named:
  - DREB2A
  arath_genes_outside_any_module: []
  notes: DREB2A sits in the heat stress module as an HSFA1 target.
- name: Hypoxia sensing (N-degron pathway of ERF-VII factors)
  group: abiotic_stress
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Iron deficiency response and uptake
  group: abiotic_stress
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Phosphate starvation response
  group: abiotic_stress
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Pectin, xyloglucan and callose biosynthesis
  group: cell_wall
  coverage: NO_MODULE
  kegg:
  - ath00040 Pentose and glucuronate interconversions
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Nucleotide sugar interconversion
  group: central_metabolism
  coverage: NO_MODULE
  kegg:
  - ath00520 Amino sugar and nucleotide sugar metabolism
  - ath00541 Biosynthesis of various nucleotide sugars
  modules: []
  related_modules:
  - udp_glucose_and_udp_galactose_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The UDP-glucose/UDP-galactose module is bacterial.
- name: Ascorbate biosynthesis (Smirnoff-Wheeler, L-galactose route)
  group: cofactors_and_vitamins
  coverage: NO_MODULE
  kegg:
  - ath00053 Ascorbate and aldarate metabolism
  modules: []
  related_modules:
  - erythroascorbate_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The erythroascorbate module is the fungal analogue, not the plant pathway.
- name: Molybdenum cofactor biosynthesis
  group: cofactors_and_vitamins
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules:
  - molybdenum_cofactor_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The existing module is prokaryotic.
- name: Tocopherol, plastoquinone and phylloquinone biosynthesis
  group: cofactors_and_vitamins
  coverage: NO_MODULE
  kegg:
  - ath00130 Ubiquinone and other terpenoid-quinone biosynthesis
  modules: []
  related_modules:
  - ubiquinone_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Abscisic acid biosynthesis
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00906 Carotenoid biosynthesis
  modules: []
  related_modules: []
  arath_genes_named:
  - NCED3
  arath_genes_outside_any_module:
  - NCED3
  notes: The ABA signaling module excludes biosynthesis from its boundary.
- name: Auxin biosynthesis (TAA/YUCCA indole-3-pyruvate route)
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00380 Tryptophan metabolism
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Brassinosteroid biosynthesis
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00905 Brassinosteroid biosynthesis
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Cytokinin biosynthesis
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00908 Zeatin biosynthesis
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Ethylene biosynthesis
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00270 Cysteine and methionine metabolism
  modules: []
  related_modules:
  - methionine_salvage_mta_cycle
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Jasmonate biosynthesis (oxylipin pathway)
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg:
  - ath00592 alpha-Linolenic acid metabolism
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Strigolactone biosynthesis
  group: hormone_biosynthesis
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Cutin, suberin and cuticular wax biosynthesis
  group: lipids
  coverage: NO_MODULE
  kegg:
  - ath00073 Cutin, suberine and wax biosynthesis
  modules: []
  related_modules: []
  arath_genes_named:
  - CER1
  arath_genes_outside_any_module:
  - CER1
  notes: null
- name: Fatty acid desaturation
  group: lipids
  coverage: NO_MODULE
  kegg:
  - ath01040 Biosynthesis of unsaturated fatty acids
  modules: []
  related_modules: []
  arath_genes_named:
  - FAD2
  arath_genes_outside_any_module:
  - FAD2
  notes: null
- name: Galactolipid (thylakoid membrane lipid) biosynthesis
  group: lipids
  coverage: NO_MODULE
  kegg:
  - ath00561 Glycerolipid metabolism
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Phytosterol biosynthesis (cycloartenol route)
  group: lipids
  coverage: NO_MODULE
  kegg:
  - ath00100 Steroid biosynthesis
  modules: []
  related_modules:
  - sterol_commitment_squalene_to_lanosterol
  - ergosterol_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Related modules use the lanosterol route of animals and fungi.
- name: Plastid de novo fatty acid synthesis (type II FAS)
  group: lipids
  coverage: NO_MODULE
  kegg:
  - ath00061 Fatty acid biosynthesis
  modules: []
  related_modules:
  - fatty_acid_de_novo_synthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The existing module is the cytosolic type I FAS.
- name: Ammonium assimilation (GS/GOGAT)
  group: nitrogen_and_sulfur
  coverage: NO_MODULE
  kegg:
  - ath00910 Nitrogen metabolism
  - ath00250 Alanine, aspartate and glutamate metabolism
  modules: []
  related_modules:
  - nitrogen_assimilation_glutamate_glutamine
  - glutamate_glutamine_ammonia_hub
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Related modules are fungal and human.
- name: Nitrate assimilation (nitrate reductase, nitrite reductase)
  group: nitrogen_and_sulfur
  coverage: NO_MODULE
  kegg:
  - ath00910 Nitrogen metabolism
  modules: []
  related_modules:
  - bacterial_assimilatory_nitrate_reduction
  - molybdenum_cofactor_biosynthesis
  arath_genes_named:
  - CHL1
  arath_genes_outside_any_module:
  - CHL1
  notes: CHL1 (NRT1.1) is the nitrate transporter/sensor, not an assimilation enzyme.
- name: Autophagy
  group: organelles
  coverage: NO_MODULE
  kegg:
  - ath04136 Autophagy - other
  modules: []
  related_modules:
  - metazoan_autophagosome_biogenesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Chloroplast protein import (TOC/TIC)
  group: organelles
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Starch synthesis and degradation
  group: photosynthesis_and_carbon
  coverage: NO_MODULE
  kegg:
  - ath00500 Starch and sucrose metabolism
  modules: []
  related_modules:
  - tres_mak_glge_branched_alpha_glucan_biosynthesis
  - glycogen_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Related modules are bacterial or animal alpha-glucan pathways.
- name: Sucrose synthesis and degradation
  group: photosynthesis_and_carbon
  coverage: NO_MODULE
  kegg:
  - ath00500 Starch and sucrose metabolism
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Blue-light signaling (cryptochromes and phototropins)
  group: signaling
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named:
  - CRY1
  - CRY2
  arath_genes_outside_any_module: []
  notes: CRY1 and CRY2 sit in the photomorphogenesis and photoperiod modules as inputs; there is no module
    for blue-light signaling or phototropism itself.
- name: Karrikin (KAI2) signaling
  group: signaling
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: UV-B signaling (UVR8)
  group: signaling
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named:
  - UVR8
  arath_genes_outside_any_module:
  - UVR8
  notes: null
- name: siRNA, tasiRNA and RNA-directed DNA methylation
  group: small_rna_and_chromatin
  coverage: NO_MODULE
  kegg: []
  modules: []
  related_modules: []
  arath_genes_named:
  - RDR6
  arath_genes_outside_any_module: []
  notes: RDR6 sits in the miRNA biogenesis module.
- name: Flavonoid, flavonol and anthocyanin biosynthesis
  group: specialised_metabolism
  coverage: NO_MODULE
  kegg:
  - ath00941 Flavonoid biosynthesis
  - ath00944 Flavone and flavonol biosynthesis
  - ath00942 Anthocyanin biosynthesis
  modules: []
  related_modules: []
  arath_genes_named:
  - TT8
  - TTG1
  arath_genes_outside_any_module:
  - TT8
  notes: TT8 and TTG1 are the bHLH and WD40 parts of the MBW complex that activates late flavonoid genes;
    TTG1 sits in the trichome module.
- name: Indolic glucosinolate biosynthesis and its MYB regulation
  group: specialised_metabolism
  coverage: NO_MODULE
  kegg:
  - ath00966 Glucosinolate biosynthesis
  modules: []
  related_modules: []
  arath_genes_named:
  - MYB34
  - MYB51
  - MYB122
  arath_genes_outside_any_module:
  - MYB122
  - MYB34
  - MYB51
  notes: CYP79B2/B3 sit in the camalexin module; the indole glucosinolate branch beyond indole-3-acetaldoxime
    has no module.
- name: Mono-, sesqui- and triterpenoid biosynthesis
  group: specialised_metabolism
  coverage: NO_MODULE
  kegg:
  - ath00902 Monoterpenoid biosynthesis
  - ath00909 Sesquiterpenoid and triterpenoid biosynthesis
  modules: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Branched-chain amino acid biosynthesis
  group: amino_acids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00290 Valine, leucine and isoleucine biosynthesis
  modules:
  - module: branched_chain_amino_acid_biosynthesis
    title: L-valine, L-leucine, and L-isoleucine biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Glutathione biosynthesis
  group: amino_acids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00480 Glutathione metabolism
  modules:
  - module: glutathione_biosynthesis
    title: Glutathione biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Histidine biosynthesis
  group: amino_acids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00340 Histidine metabolism
  modules:
  - module: histidine_biosynthesis
    title: L-histidine biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Polyamine metabolism
  group: amino_acids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00330 Arginine and proline metabolism
  modules:
  - module: polyamine_metabolism
    title: Eukaryotic polyamine metabolism (biosynthesis, back-conversion and antizyme feedback)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Glycolysis and gluconeogenesis
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00010 Glycolysis / Gluconeogenesis
  modules:
  - module: emp_glycolysis
    title: Generic Embden-Meyerhof-Parnas (EMP) glycolysis module
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  - module: gluconeogenesis
    title: Generic gluconeogenesis module
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Inositol phosphate metabolism
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00562 Inositol phosphate metabolism
  modules:
  - module: myo_inositol_and_inositol_phosphate_biosynthesis
    title: myo-Inositol and inositol (pyro)phosphate biosynthesis (MIPS/IMPase and the PLC-IPMK-IPK1-IP6K-PPIP5K
      route)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Oxidative phosphorylation
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00190 Oxidative phosphorylation
  modules:
  - module: oxphos
    title: Oxidative phosphorylation (OXPHOS) module
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Pentose phosphate pathway
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00030 Pentose phosphate pathway
  modules:
  - module: pentose_phosphate_pathway
    title: Pentose phosphate pathway
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Tricarboxylic acid cycle
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00020 Citrate cycle (TCA cycle)
  modules:
  - module: tca_cycle
    title: Tricarboxylic acid cycle
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Biotin biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00780 Biotin metabolism
  modules:
  - module: biotin_biosynthesis
    title: De novo biotin biosynthesis (pimelate-thioester supply and BioF-BioA-BioD-BioB ring assembly)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Coenzyme A biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00770 Pantothenate and CoA biosynthesis
  modules:
  - module: coenzyme_a_biosynthesis
    title: Pantoate-derived coenzyme A biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: MEP and mevalonate isoprenoid precursor supply
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00900 Terpenoid backbone biosynthesis
  modules:
  - module: mep_isoprenoid_precursor_biosynthesis
    title: MEP isoprenoid precursor biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  - module: mevalonate_pathway
    title: Mevalonate pathway (acetyl-CoA -> isopentenyl diphosphate)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  - module: isoprenoid_diphosphate_biosynthesis
    title: Isoprenoid (prenyl) diphosphate biosynthesis (IPP/DMAPP -> GPP -> FPP -> GGPP)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: NAD biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00760 Nicotinate and nicotinamide metabolism
  modules:
  - module: nad_biosynthesis_salvage
    title: L-aspartate de novo and selected salvage routes to NAD+
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Riboflavin biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00740 Riboflavin metabolism
  modules:
  - module: riboflavin_biosynthesis
    title: De novo riboflavin biosynthesis and flavin cofactor activation
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Vitamin B6 metabolism
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00750 Vitamin B6 metabolism
  modules:
  - module: vitamin_b6_plp_metabolism
    title: Vitamin B6 (pyridoxal 5'-phosphate) supply by PdxS/PdxT synthesis or vitamer salvage, and PLP
      homeostasis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Peroxisomal fatty acid beta-oxidation
  group: lipids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00071 Fatty acid degradation
  modules:
  - module: peroxisomal_beta_oxidation
    title: Peroxisomal fatty-acid beta-oxidation
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Phospholipid biosynthesis
  group: lipids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00564 Glycerophospholipid metabolism
  modules:
  - module: cdp_dag_phospholipid_synthesis
    title: CDP-diacylglycerol pathway of phospholipid synthesis (PS, PE, PC by methylation, PI, PG and
      cardiolipin)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Sphingolipid biosynthesis
  group: lipids
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00600 Sphingolipid metabolism
  modules:
  - module: sphingolipid_de_novo_synthesis
    title: De novo sphingolipid biosynthesis (ceramide core, with fungal inositol-phosphorylceramide head
      groups)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Sulfate assimilation
  group: nitrogen_and_sulfur
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00920 Sulfur metabolism
  modules:
  - module: aps_dependent_assimilatory_sulfate_reduction
    title: Assimilatory sulfate reduction to sulfide (APS and PAPS routes)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  - module: paps_sulfate_activation
    title: PAPS biosynthesis and Golgi import (sulfate activation) (PAPSS1/2 -> SLC35B2/3)
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Peroxisome biogenesis and matrix protein import
  group: organelles
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath04146 Peroxisome
  modules:
  - module: peroxisome-lifecycle
    title: Peroxisome lifecycle and matrix protein import module
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Trehalose 6-phosphate metabolism
  group: photosynthesis_and_carbon
  coverage: MODULE_WITHOUT_ARABIDOPSIS
  kegg:
  - ath00500 Starch and sucrose metabolism
  modules:
  - module: trehalose_metabolism
    title: Trehalose synthesis via trehalose 6-phosphate and trehalase hydrolysis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Aspartate-family amino acid biosynthesis (Lys, Thr, Met)
  group: amino_acids
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00300 Lysine biosynthesis
  - ath00260 Glycine, serine and threonine metabolism
  - ath00270 Cysteine and methionine metabolism
  modules:
  - module: aspartate_family_threonine_biosynthesis
    title: L-threonine biosynthesis from L-aspartate
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  - module: methionine_biosynthesis
    title: L-methionine biosynthesis (from homoserine)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules:
  - lysine_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The lysine module is the succinylated DAP route; plants use the LL-diaminopimelate aminotransferase
    variant.
- name: GABA shunt
  group: amino_acids
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00250 Alanine, aspartate and glutamate metabolism
  modules:
  - module: gaba_shunt
    title: GABA shunt (glutamate to GABA to succinate)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Proline and arginine metabolism
  group: amino_acids
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00330 Arginine and proline metabolism
  - ath00220 Arginine biosynthesis
  modules:
  - module: proline_metabolism
    title: Proline-P5C biosynthesis and catabolism
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  - module: arginine_catabolism_arginase_pathway
    title: Arginine catabolism via arginase and ornithine aminotransferase
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules:
  - arginine_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The arginine biosynthesis module is scoped to microbes and fungi.
- name: Shikimate and aromatic amino acid biosynthesis
  group: amino_acids
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00400 Phenylalanine, tyrosine and tryptophan biosynthesis
  modules:
  - module: bacterial_shikimate_chorismate_biosynthesis
    title: Shikimate pathway to chorismate
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  - module: phenylalanine_tyrosine_biosynthesis
    title: L-phenylalanine and L-tyrosine biosynthesis from chorismate
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  - module: tryptophan_biosynthesis
    title: L-tryptophan biosynthesis
    status: DRAFT
    mentions_arabidopsis: false
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Cellulose biosynthesis
  group: cell_wall
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg: []
  modules:
  - module: cellulose_biosynthesis
    title: Plant cellulose biosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Xylan biosynthesis
  group: cell_wall
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg: []
  modules:
  - module: xylan_biosynthesis
    title: Plant xylan (glucuronoxylan) biosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Alcoholic fermentation
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00010 Glycolysis / Gluconeogenesis
  modules:
  - module: alcoholic_fermentation
    title: Alcoholic fermentation of pyruvate to ethanol
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Galactose metabolism (Leloir)
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00052 Galactose metabolism
  modules:
  - module: galactose_leloir_pathway
    title: Galactose catabolism (Leloir pathway)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Glyoxylate cycle
  group: central_metabolism
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00630 Glyoxylate and dicarboxylate metabolism
  modules:
  - module: glyoxylate_cycle
    title: Glyoxylate cycle
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Folate biosynthesis and one-carbon metabolism
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00790 Folate biosynthesis
  - ath00670 One carbon pool by folate
  modules:
  - module: tetrahydrofolate_biosynthesis
    title: De novo tetrahydrofolate and folylpolyglutamate biosynthesis
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  - module: folate_one_carbon_interconversion
    title: Folate one-carbon carrier-state interconversion
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Siroheme biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00860 Porphyrin metabolism
  modules:
  - module: siroheme_biosynthesis
    title: Siroheme biosynthesis from uroporphyrinogen III
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Thiamine biosynthesis
  group: cofactors_and_vitamins
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00730 Thiamine metabolism
  modules:
  - module: eukaryotic_thiamine_biosynthesis
    title: Eukaryotic (THI4/THI5-type) de novo thiamine diphosphate biosynthesis
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Ureide catabolism
  group: nitrogen_and_sulfur
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00230 Purine metabolism
  modules:
  - module: ureide_urea_catabolism
    title: Ureide pathway - nitrogen recovery from allantoin via urea to ammonia
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: ER unfolded protein response
  group: organelles
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath04141 Protein processing in endoplasmic reticulum
  modules:
  - module: er_unfolded_protein_response
    title: Endoplasmic reticulum unfolded protein response
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Calvin-Benson-Bassham cycle (carbon fixation)
  group: photosynthesis_and_carbon
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00710 Carbon fixation by Calvin cycle
  modules:
  - module: photosynthesis
    title: Oxygenic photosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: A part of the taxon-neutral photosynthesis module.
- name: Chlorophyll biosynthesis
  group: photosynthesis_and_carbon
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00860 Porphyrin metabolism
  modules:
  - module: photosynthesis
    title: Oxygenic photosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules:
  - heme_biosynthesis
  - siroheme_biosynthesis
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Included in the photosynthesis module only as a supporting part (magnesium chelatase onward).
    Chlorophyll degradation is not covered.
- name: Photosynthetic light reactions and antenna complexes
  group: photosynthesis_and_carbon
  coverage: MODULE_WITHOUT_ARATH_GENES
  kegg:
  - ath00195 Photosynthesis
  - ath00196 Photosynthesis - antenna proteins
  modules:
  - module: photosynthesis
    title: Oxygenic photosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Heat stress response
  group: abiotic_stress
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: plant_hsfa1_heat_stress_response
    title: HSFA1-driven heat stress response in Arabidopsis
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AT1G32330
    - AT1G74310
    - AT2G26150
    - AT3G02990
    - AT4G17750
    - AT5G02500
    - AT5G03720
    - AT5G16820
    - AT5G52640
    - DREB2A
    - HSP17.6A
    - HSP17.7
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Salt tolerance (SOS pathway)
  group: abiotic_stress
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: sos_salt_tolerance
    title: Salt Overly Sensitive (SOS) pathway (SOS3/CBL4 - SOS2/CIPK24 - SOS1 Na+/H+ antiporter)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CBL10
    - CBL4
    - CIPK24
    - SOS1
  related_modules: []
  arath_genes_named:
  - SOS1
  - CIPK24
  - HKT1
  arath_genes_outside_any_module:
  - HKT1
  notes: null
- name: Floral meristem and floral organ identity
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: floral_meristem_identity
    title: Specification of floral meristem identity at the Arabidopsis shoot apex
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AP1
    - AP2
    - CAL
    - FD
    - FT
    - FUL
    - LFY
    - SOC1
    - TFL1
    - UFO
  - module: floral_organ_identity_abce
    title: ABCE model of floral organ identity (MADS floral quartets)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AG
    - AP1
    - AP2
    - AP3
    - PI
    - SEP1
    - SEP2
    - SEP3
    - SEP4
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Flowering time (photoperiod, vernalization, autonomous pathways)
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: photoperiodic_flowering_co_ft
    title: Photoperiodic (long-day) flowering via the CONSTANS-FLOWERING LOCUS T pathway (Arabidopsis)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CDF1
    - CO
    - COP1
    - CRY2
    - FD
    - FKF1
    - FT
    - GI
    - PHYA
    - SOC1
    - SPA1
    - ZTL
  - module: vernalization_flc_silencing
    title: FRIGIDA-dependent FLC activation and vernalization-induced Polycomb silencing of FLC
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CLF
    - FIE
    - FLC
    - FRI
    - FT
    - LHP1
    - MSI1
    - SOC1
    - SVP
    - SWN
    - VAL1
    - VIN3
    - VRN1
    - VRN2
    - VRN5
  - module: autonomous_flowering_pathway
    title: Autonomous flowering pathway repressing FLOWERING LOCUS C (Arabidopsis)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - FCA
    - FLC
    - FLD
    - FPA
    - FT
    - FVE
    - FY
    - LD
    - SOC1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Root radial patterning (SHR-SCR)
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: root_radial_patterning_shr_scr
    title: Root ground-tissue radial patterning by the SHORT-ROOT-SCARECROW-BIRD module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CYCD6-1
    - JKD
    - MGP
    - SCR
    - SHR
    - WOX5
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Shoot apical meristem maintenance (CLV-WUS)
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: shoot_meristem_clv_wus_feedback
    title: CLAVATA-WUSCHEL negative feedback loop in shoot apical meristem stem-cell homeostasis
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - BAM1
    - CLV1
    - CLV2
    - CLV3
    - CRN
    - STM
    - WUS
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Stomatal development
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: stomatal_lineage_development
    title: Stomatal lineage progression and spacing (EPF-ERECTA-YODA-MAPK and SPCH/MUTE/FAMA-SCRM)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - EPF2
    - ERECTA
    - FAMA
    - ICE1
    - MKK4
    - MKK5
    - MPK3
    - MPK6
    - MUTE
    - SPCH
    - TMM
    - YDA
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Trichome initiation and patterning
  group: development
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: trichome_initiation_mbw
    title: Leaf trichome initiation and patterning by the MYB-bHLH-WD40 activator complex and R3 MYB lateral
      inhibitors
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CPC
    - EGL3
    - GL1
    - GL2
    - GL3
    - TRY
    - TTG1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Gibberellin biosynthesis
  group: hormone_biosynthesis
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00904 Diterpenoid biosynthesis
  modules:
  - module: gibberellin_biosynthesis
    title: Bioactive gibberellin (GA4/GA1) biosynthesis from geranylgeranyl diphosphate
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - GA1
    - GA2
    - GA20OX1
    - GA3
    - GA3OX1
    - KAO1
    - KAO2
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Salicylic acid biosynthesis and NPR1 signaling
  group: hormone_biosynthesis
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: salicylic_acid_biosynthesis_npr1_signaling
    title: Salicylic acid biosynthesis (isochorismate route) and NPR1-dependent defence signalling
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - ICS1
    - NPR1
    - WRKY70
  related_modules: []
  arath_genes_named:
  - ICS1
  - NPR1
  - WRKY70
  arath_genes_outside_any_module: []
  notes: null
- name: Bacterial PAMP perception (FLS2/EFR)
  group: immunity
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04626 Plant-pathogen interaction
  - ath04016 MAPK signaling pathway - plant
  modules:
  - module: bacterial_pamp_lrr_receptor_signaling
    title: Bacterial PAMP perception by LRR receptor kinases (FLS2/EFR with BAK1)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - BAK1
    - BIK1
    - EFR
    - FLS2
    - MAPKKK5
    - MKK4
    - MKK5
    - MPK3
    - MPK6
    - RBOHD
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Chitin perception
  group: immunity
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04016 MAPK signaling pathway - plant
  modules:
  - module: chitin_perception
    title: Plant chitin perception by LysM receptor complexes
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - BIK1
    - CERK1
    - LYK4
    - LYK5
    - MAPKKK5
    - MKK4
    - MKK5
    - MPK3
    - MPK6
    - PBL1
    - PBL27
    - RBOHD
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: NLR (effector-triggered) immunity
  group: immunity
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04626 Plant-pathogen interaction
  modules:
  - module: plant_nlr_resistosome_signaling
    title: Plant NLR resistosome activation and signalling
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - EDS1
    - PAD4
  related_modules: []
  arath_genes_named:
  - RPM1
  - RPS2
  arath_genes_outside_any_module:
  - RPM1
  - RPS2
  notes: null
- name: Microsomal fatty acid elongation
  group: lipids
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00062 Fatty acid elongation
  modules:
  - module: fatty_acid_elongation_cycle
    title: Microsomal fatty-acid elongation cycle (ELOVL or KCS -> KAR -> HACD -> ECR)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CUT1
    - ECR
    - FAE1
    - KCR1
    - PAS2
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Triacylglycerol (seed oil) biosynthesis
  group: lipids
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00561 Glycerolipid metabolism
  modules:
  - module: seed_triacylglycerol_biosynthesis
    title: Plant seed triacylglycerol (oil) biosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - DGAT1
  - module: triacylglycerol_biosynthesis
    title: Glycerolipid / triacylglycerol biosynthesis (glycerol-3-phosphate and DHAP routes)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members: []
  related_modules: []
  arath_genes_named:
  - DGAT1
  - WRI1
  arath_genes_outside_any_module:
  - WRI1
  notes: null
- name: Nuclear envelope LINC complex
  group: organelles
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: linc_complex
    title: LINC complex (SUN-KASH nuclear envelope bridge) module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - SUN1
    - SUN2
    - WIP1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Photorespiration (C2 cycle)
  group: photosynthesis_and_carbon
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00630 Glyoxylate and dicarboxylate metabolism
  modules:
  - module: photorespiration_c2_cycle
    title: Photorespiratory C2 cycle (2-phosphoglycolate to 3-phosphoglycerate) in land plants
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AGT1
    - CAT2
    - GDCH
    - GDCST
    - GGAT1
    - GGAT2
    - GLDP1
    - GLDP2
    - GLN2
    - GLO1
    - GLO2
    - GLU1
    - GLYK
    - HPR
    - HPR2
    - PGLP1
    - PLGG1
    - SHM1
    - mtLPD1
    - mtLPD2
  related_modules:
  - glycolate_glyoxylate_assimilation
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: The photorespiration module includes glycine_cleavage_system by reference; the glycolate/glyoxylate
    module is bacterial.
- name: Abscisic acid signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: abscisic_acid_signaling
    title: Abscisic acid core signaling (PYR/PYL receptor - clade A PP2C - SnRK2 - ABF/ABI5 and SLAC1
      outputs)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - ABI1
    - ABI5
    - OST1
    - PYR1
    - SLAC1
    - SnRK2.2
    - SnRK2.3
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Auxin nuclear signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: auxin_nuclear_signaling
    title: Nuclear auxin signaling (TIR1/AFB-Aux/IAA-TOPLESS-ARF module)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AFB2
    - ARF19
    - ARF5
    - ARF7
    - IAA12
    - IAA17
    - TIR1
    - TPL
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Brassinosteroid signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: brassinosteroid_signaling
    title: Brassinosteroid signal perception and relay to BZR1/BES1 transcription factors
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - BAK1
    - BES1
    - BIN2
    - BKI1
    - BRI1
    - BSK1
    - BSU1
    - BZR1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Circadian clock
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04712 Circadian rhythm - plant
  modules:
  - module: plant_circadian_clock_oscillator
    title: Arabidopsis core circadian oscillator (CCA1/LHY - PRR - evening complex - ZTL)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CCA1
    - ELF3
    - ELF4
    - GI
    - LHY
    - LUX
    - PRR5
    - PRR7
    - PRR9
    - TOC1
    - ZTL
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Cytokinin signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: cytokinin_two_component_signaling
    title: Cytokinin two-component (His-Asp phosphorelay) signaling in Arabidopsis
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AHK2
    - AHK3
    - AHK4
    - AHP1
    - ARR1
    - ARR12
    - ARR5
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Ethylene signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: ethylene_signaling
    title: Ethylene signaling (ETR/ERS receptor-CTR1-EIN2-EBF-EIN3/EIL1 module)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CTR1
    - EBF1
    - EBF2
    - EIL1
    - EIN2
    - EIN3
    - ERS1
    - ETR1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Gibberellin signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: gibberellin_della_signaling
    title: Gibberellin perception and DELLA derepression (GID1-DELLA-SCF(SLY1) module)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - GAI
    - GID1A
    - GID1B
    - GID1C
    - PIF3
    - PIF4
    - RGA
    - SLY1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Jasmonate signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath04075 Plant hormone signal transduction
  modules:
  - module: jasmonate_coi1_jaz_signaling
    title: Jasmonate perception and JAZ derepression (JAR1-COI1-JAZ-NINJA/TPL-MYC module)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - COI1
    - JAR1
    - JAZ1
    - MYC2
    - MYC3
    - NINJA
    - TPL
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Phytochrome signaling and photomorphogenesis
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: phytochrome_photomorphogenesis
    title: Phytochrome control of photomorphogenesis (phyA/phyB - PIF - COP1/SPA - HY5)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - COP1
    - CRY1
    - HY5
    - PHYA
    - PHYB
    - PIF1
    - PIF3
    - PIF4
    - SPA1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Polar auxin transport
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: auxin_polar_transport
    title: Polar (cell-to-cell) auxin transport
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - ABCB19
    - AUX1
    - D6PK
    - PID
    - PIN1
    - PIN2
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Strigolactone signaling
  group: signaling
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: strigolactone_signaling_shoot_branching
    title: Strigolactone perception and D14-MAX2-SMXL signalling in shoot-branching control
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - BRC1
    - D14
    - MAX2
    - SMXL6
    - SMXL7
    - SMXL8
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Polycomb (PRC2) silencing
  group: small_rna_and_chromatin
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath03083 Polycomb repressive complex
  modules:
  - module: vernalization_flc_silencing
    title: FRIGIDA-dependent FLC activation and vernalization-induced Polycomb silencing of FLC
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CLF
    - FIE
    - FLC
    - FRI
    - FT
    - LHP1
    - MSI1
    - SOC1
    - SVP
    - SWN
    - VAL1
    - VIN3
    - VRN1
    - VRN2
    - VRN5
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Covered only as it acts at FLC.
- name: miRNA biogenesis and AGO1 loading
  group: small_rna_and_chromatin
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: plant_mirna_biogenesis
    title: Plant miRNA biogenesis and AGO1 RISC loading
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AGO1
    - DCL1
    - DRB1
    - HEN1
    - RDR6
    - SERRATE
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Aliphatic glucosinolate biosynthesis and myrosinase defence
  group: specialised_metabolism
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00966 Glucosinolate biosynthesis
  modules:
  - module: aliphatic_glucosinolate_myrosinase_defense
    title: Aliphatic glucosinolate biosynthesis and myrosinase activation (glucosinolate-myrosinase defense
      system)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - AOP2
    - BCAT3
    - BCAT4
    - CYP79F1
    - CYP79F2
    - CYP83A1
    - ESP
    - FMOGS-OX1
    - GGP1
    - GSTF11
    - GSTU20
    - IIL1
    - IMDH1
    - MAM1
    - MAM3
    - NSP1
    - SOT17
    - SOT18
    - SSU3
    - SUR1
    - TGG1
    - TGG2
    - UGT74C1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Camalexin biosynthesis
  group: specialised_metabolism
  coverage: MODULE_WITH_ARATH_GENES
  kegg: []
  modules:
  - module: camalexin_biosynthesis
    title: Camalexin biosynthesis (tryptophan-derived indole phytoalexin)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CYP71A12
    - CYP71A13
    - CYP71B15
    - CYP79B2
    - CYP79B3
    - GGP1
    - GSTF6
    - MPK3
    - MPK6
    - WRKY33
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
- name: Carotenoid biosynthesis
  group: specialised_metabolism
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00906 Carotenoid biosynthesis
  modules:
  - module: carotene_backbone_biosynthesis
    title: Carotenoid biosynthesis I — carotene backbone (GGPP -> phytoene -> lycopene -> cyclic carotenes)
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - CRTISO
    - LCYB
    - LCYE
    - PDS
    - PSY
    - Z-ISO
    - ZDS
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: Covers carotenes only; xanthophylls are not modelled.
- name: Monolignol (lignin) biosynthesis
  group: specialised_metabolism
  coverage: MODULE_WITH_ARATH_GENES
  kegg:
  - ath00940 Phenylpropanoid biosynthesis
  modules:
  - module: lignin_monolignol_biosynthesis
    title: Plant lignin (monolignol) biosynthesis module
    status: DRAFT
    mentions_arabidopsis: true
    arath_reviewed_members:
    - PAL1
  related_modules: []
  arath_genes_named: []
  arath_genes_outside_any_module: []
  notes: null
