source: https://s3ftp.flybase.org/releases/FB2026_03/precomputed_files/genes/gene_group_data_fb_2026_03.tsv.gz release: fb_2026_03 n_groups: 1836 n_terminal_groups_with_members: 1413 n_member_genes: 8607 group_size: median: 4 max: 273 n_groups_le_10_members: 1166 n_groups_named_complex: 315 n_groups_named_unclassified: 88 top_level_roots: - id: FBgg0001715 symbol: ENZ name: ENZYMES n_terminal_groups: 510 - id: FBgg0001934 symbol: TMT name: TRANSMEMBRANE TRANSPORTERS n_terminal_groups: 133 - id: FBgg0000459 symbol: TRNA name: TRANSFER RNAS n_terminal_groups: 45 - id: FBgg0001106 symbol: TM-R name: TRANSMEMBRANE RECEPTORS n_terminal_groups: 36 - id: FBgg0000745 symbol: TFS name: TRANSCRIPTION FACTORS n_terminal_groups: 34 - id: FBgg0001798 symbol: PSENZ name: PSEUDOENZYMES n_terminal_groups: 16 - id: FBgg0001105 symbol: RLIG name: RECEPTOR LIGANDS n_terminal_groups: 14 - id: FBgg0002156 symbol: HDP name: HOST DEFENSE PEPTIDES n_terminal_groups: 12 - id: FBgg0001904 symbol: MPT name: MITOCHONDRIAL PROTEIN IMPORT COMPLEXES n_terminal_groups: 11 - id: FBgg0000341 symbol: RAS-SF-GEF name: RAS SUPERFAMILY GUANINE NUCLEOTIDE EXCHANGE FACTORS n_terminal_groups: 10 - id: FBgg0001725 symbol: TEFC name: TRANSCRIPTION ELONGATION FACTOR COMPLEXES n_terminal_groups: 10 - id: FBgg0001841 symbol: OXPHOS-V name: MITOCHONDRIAL OXPHOS COMPLEX VARIANTS n_terminal_groups: 10 - id: FBgg0000552 symbol: ABC-TL name: ATP-BINDING CASSETTE TRANSPORTER-LIKE n_terminal_groups: 10 - id: FBgg0000501 symbol: HSP name: HEAT SHOCK PROTEINS n_terminal_groups: 9 - id: FBgg0000309 symbol: PCG-C name: POLYCOMB GROUP RING FINGER COMPLEXES n_terminal_groups: 8 drome_reviews: n_reviewed_genes: 314 n_reviewed_in_any_group: 257 n_groups_with_any_review: 217 n_groups_fully_reviewed: 54 group_coverage: - id: FBgg0000177 symbol: RHG name: RHG PROTEINS n_members: 6 n_reviewed: 6 reviewed: - HtrA2 - Prx4 - grim - hid - rpr - skl - id: FBgg0001062 symbol: GSC name: GAMMA SECRETASE COMPLEX n_members: 4 n_reviewed: 4 reviewed: - Nct - Psn - aph-1 - pen-2 - id: FBgg0001644 symbol: IRM name: IRRE CELL RECOGNITION MODULE CELL ADHESION MOLECULES n_members: 4 n_reviewed: 4 reviewed: - hbs - kirre - rst - sns - id: FBgg0002116 symbol: CCC-911 name: CHECKPOINT CLAMP COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Hus1-like - Rad1 - Rad9 - id: FBgg0002000 symbol: GATCAB name: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE COMPLEX n_members: 3 n_reviewed: 3 reviewed: - GatA - GatB - GatC - id: FBgg0001919 symbol: LKB1C name: LKB1-STRAD-MO25 SERINE/THREONINE PROTEIN KINASE COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Lkb1 - Mo25 - Stlk - id: FBgg0001923 symbol: MRN name: MRN COMPLEX n_members: 3 n_reviewed: 3 reviewed: - mre11 - nbs - rad50 - id: FBgg0000096 symbol: RZZ name: RZZ COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Zw10 - Zwilch - rod - id: FBgg0000614 symbol: NF-KB name: NUCLEAR FACTOR - KAPPA B n_members: 3 n_reviewed: 3 reviewed: - Dif - Rel - dl - id: FBgg0000153 symbol: MCC name: MON1-CCZ1 COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Bulli - Ccz1 - Mon1 - id: FBgg0000720 symbol: ELBA name: ELBA BOUNDARY FACTOR COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Elba1 - Elba2 - Elba3 - id: FBgg0000533 symbol: GAT1 name: GATOR1 COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Iml1 - Nprl2 - Nprl3 - id: FBgg0002066 symbol: AMPK-C name: AMPK COMPLEX n_members: 3 n_reviewed: 3 reviewed: - AMPKalpha - SNF4Agamma - alc - id: FBgg0002205 symbol: NFY name: CCAAT-BINDING FACTOR COMPLEX SUBUNITS n_members: 3 n_reviewed: 3 reviewed: - Nf-YA - Nf-YB - Nf-YC - id: FBgg0000649 symbol: FER name: FERRITINS n_members: 3 n_reviewed: 3 reviewed: - Fer1HCH - Fer2LCH - Fer3HCH - id: FBgg0000773 symbol: CBFTF name: CCAAT-BINDING FACTOR COMPLEX n_members: 3 n_reviewed: 3 reviewed: - Nf-YA - Nf-YB - Nf-YC - id: FBgg0000295 symbol: CAF-1 name: CHROMATIN ASSEMBLY FACTOR 1 n_members: 3 n_reviewed: 3 reviewed: - Caf1-105 - Caf1-180 - Caf1-55 - id: FBgg0001979 symbol: SK-CAM name: SNS-KIRRE CELL ADHESION COMPLEX n_members: 2 n_reviewed: 2 reviewed: - kirre - sns - id: FBgg0002114 symbol: METWD name: METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Mettl1 - wuho - id: FBgg0001981 symbol: ECUP name: EIF4E-CUP COMPLEX n_members: 2 n_reviewed: 2 reviewed: - cup - eIF4E1 - id: FBgg0000575 symbol: TLNF-CRF name: CYTOPLASMIC TRANSLATION RELEASE FACTORS n_members: 2 n_reviewed: 2 reviewed: - eRF1 - eRF3 - id: FBgg0002017 symbol: CLPXP name: MITOCHONDRIAL CLPXP COMPLEX n_members: 2 n_reviewed: 2 reviewed: - ClpP - ClpX - id: FBgg0001750 symbol: CGLR name: CGAS-LIKE RECEPTORS n_members: 2 n_reviewed: 2 reviewed: - cGlr1 - cGlr2 - id: FBgg0000191 symbol: E3-IAP name: INHIBITOR OF APOPTOSIS UBIQUITIN LIGASES n_members: 2 n_reviewed: 2 reviewed: - Diap1 - Diap2 - id: FBgg0001977 symbol: RS-CAM name: RST-SNS CELL ADHESION COMPLEX n_members: 2 n_reviewed: 2 reviewed: - rst - sns - id: FBgg0002143 symbol: MITDEG name: MITOCHONDRIAL DEGRADOSOME n_members: 2 n_reviewed: 2 reviewed: - PNPase - Suv3 - id: FBgg0001978 symbol: HR-CAM name: HBS-RST CELL ADHESION COMPLEX n_members: 2 n_reviewed: 2 reviewed: - hbs - rst - id: FBgg0002201 symbol: RABGEF-TLD name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - TRI LONGIN DOMAIN n_members: 2 n_reviewed: 2 reviewed: - Ccz1 - Mon1 - id: FBgg0002118 symbol: CLNK-C12 name: CYCLIN K-CDK12 COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Cdk12 - CycK - id: FBgg0002008 symbol: TGTC name: TRNA-GUANINE TRANSGLYCOSYLASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - CG3434 - Tgt - id: FBgg0001802 symbol: FUSF name: FUSED-SMURF UBIQUITIN LIGASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Smurf - fu - id: FBgg0002117 symbol: ATR-ATRIP name: ATR-ATRIP DNA DAMAGE-SENSING KINASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - mei-41 - mus304 - id: FBgg0002067 symbol: SREBP-SCAP name: SREBP-SCAP COMPLEX n_members: 2 n_reviewed: 2 reviewed: - SCAP - SREBP - id: FBgg0001996 symbol: DPH1-DPH2 name: DPH1-DPH2 COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Dph1 - Dph2 - id: FBgg0001971 symbol: TRFC name: ERF1-ERF3 TRANSLATION TERMINATION COMPLEX n_members: 2 n_reviewed: 2 reviewed: - eRF1 - eRF3 - id: FBgg0000592 symbol: CRAC name: CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Orai - Stim - id: FBgg0001994 symbol: TDRD3-TOP3B name: TDRD3-TOP3B TYPE IA TOPOISOMERASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Tdrd3 - Top3beta - id: FBgg0000129 symbol: APOP name: APOPTOSOME n_members: 2 n_reviewed: 2 reviewed: - Dark - Dronc - id: FBgg0001988 symbol: RIC name: RAPS-INSC COMPLEX n_members: 2 n_reviewed: 2 reviewed: - insc - pins - id: FBgg0001737 symbol: ACPC name: F-ACTIN CAPPING PROTEIN COMPLEX n_members: 2 n_reviewed: 2 reviewed: - cpa - cpb - id: FBgg0002142 symbol: GBP3MC name: GTPBP3-MTO1 COMPLEX n_members: 2 n_reviewed: 2 reviewed: - CG18528 - CG4610 - id: FBgg0002004 symbol: MTP name: MITOCHONDRIAL TRIFUNCTIONAL PROTEIN COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Mtpalpha - Mtpbeta - id: FBgg0000902 symbol: HIF name: HYPOXIA-INDUCIBLE FACTOR n_members: 2 n_reviewed: 2 reviewed: - sima - tgo - id: FBgg0001976 symbol: HK-CAM name: HBS-KIRRE CELL ADHESION COMPLEX n_members: 2 n_reviewed: 2 reviewed: - hbs - kirre - id: FBgg0002006 symbol: RNRC name: RIBONUCLEOTIDE REDUCTASE COMPLEX n_members: 2 n_reviewed: 2 reviewed: - RnrL - RnrS - id: FBgg0001735 symbol: KPC name: KIP1 UBIQUITINATION-PROMOTING COMPLEX n_members: 2 n_reviewed: 2 reviewed: - Kpc1 - Kpc2 - id: FBgg0000135 symbol: SMO name: SMOOTHENED-TYPE RECEPTORS n_members: 1 n_reviewed: 1 reviewed: - smo - id: FBgg0001948 symbol: LGIC-U name: UNCLASSIFIED LIGAND-GATED ION CHANNEL SUBUNITS n_members: 1 n_reviewed: 1 reviewed: - NtR - id: FBgg0001705 symbol: SQOR name: SULFIDE-QUINONE OXIOREDUCTASES n_members: 1 n_reviewed: 1 reviewed: - Sqor - id: FBgg0002194 symbol: CRAC-CH name: CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL SUBUNITS n_members: 1 n_reviewed: 1 reviewed: - Orai - id: FBgg0001968 symbol: ABCB-HTH name: ABCB ATP-BINDING CASSETTE TRANSPORTER HMT-1 SUBFAMILY - HALF TRANSPORTERS n_members: 1 n_reviewed: 1 reviewed: - Hmt-1 - id: FBgg0001344 symbol: HSP100 name: HEAT SHOCK PROTEIN 100 CHAPERONES n_members: 1 n_reviewed: 1 reviewed: - ClpX - id: FBgg0001622 symbol: EYA name: EYA FAMILY PROTEIN TYROSINE PHOSPHATASES n_members: 1 n_reviewed: 1 reviewed: - eya - id: FBgg0001448 symbol: M-DNED name: METALLO-TYPE DENEDDYLASES n_members: 1 n_reviewed: 1 reviewed: - CSN5 - id: FBgg0001632 symbol: CACTT name: C-ACETYLTRANSFERASES n_members: 5 n_reviewed: 4 reviewed: - Acaa - Acat1 - Gcat - Mtpbeta - id: FBgg0001193 symbol: IKB name: NUCLEAR FACTOR - KAPPA B INHIBITOR FAMILY n_members: 3 n_reviewed: 2 reviewed: - Rel - cact - id: FBgg0001066 symbol: CNM name: CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX n_members: 3 n_reviewed: 2 reviewed: - N - mam - id: FBgg0001342 symbol: HSC name: HEDGEHOG SIGNALING COMPLEX n_members: 3 n_reviewed: 2 reviewed: - ci - fu - id: FBgg0000990 symbol: ACAD name: ACYL-COA DEHYDROGENASES n_members: 8 n_reviewed: 5 reviewed: - Acadvl - Arc42 - CG4860 - Egm - Mcad - id: FBgg0001778 symbol: AGO name: ARGONAUTE ENDORIBONUCLEASES n_members: 5 n_reviewed: 3 reviewed: - AGO3 - aub - piwi - id: FBgg0000064 symbol: IAP name: INHIBITOR OF APOPTOSIS n_members: 4 n_reviewed: 2 reviewed: - Diap1 - Diap2 - id: FBgg0000870 symbol: COLYAP name: CARBON-OXYGEN LYASES, ACTING ON PHOSPHATES n_members: 2 n_reviewed: 1 reviewed: - CG8745 - id: FBgg0001082 symbol: S1CP name: S1C SERINE PEPTIDASES n_members: 2 n_reviewed: 1 reviewed: - HtrA2 - id: FBgg0000849 symbol: GMANI name: GOLGI CLASS I ALPHA-MANNOSIDASES n_members: 2 n_reviewed: 1 reviewed: - alpha-Man-Ia - id: FBgg0000210 symbol: KASH name: KASH DOMAIN GENES n_members: 2 n_reviewed: 1 reviewed: - klar - id: FBgg0001434 symbol: S14-16P name: ATP-DEPENDENT SERINE ENDOPEPTIDASES n_members: 2 n_reviewed: 1 reviewed: - ClpP - id: FBgg0000753 symbol: MADSTF name: MADS-BOX TRANSCRIPTION FACTORS n_members: 2 n_reviewed: 1 reviewed: - Mef2 - id: FBgg0001311 symbol: B3GLCNACT name: BETA 1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE n_members: 2 n_reviewed: 1 reviewed: - fng - id: FBgg0001350 symbol: B-GLUS name: BETA-GLUCOSIDASES n_members: 2 n_reviewed: 1 reviewed: - CG33090 - id: FBgg0001336 symbol: CNHLAN name: CARBON-NITROGEN HYDROLASES OF LINEAR AMIDINES n_members: 2 n_reviewed: 1 reviewed: - Arg - id: FBgg0001594 symbol: RNAHEL-U name: UNCLASSIFIED RNA HELICASES n_members: 2 n_reviewed: 1 reviewed: - Suv3 - id: FBgg0001998 symbol: EXT1-EXT2 name: EXT1-EXT2 COMPLEX n_members: 2 n_reviewed: 1 reviewed: - ttv - id: FBgg0000853 symbol: EDEM name: ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASES n_members: 2 n_reviewed: 1 reviewed: - Edem2 - id: FBgg0001054 symbol: DORS name: DORSAL GROUP n_members: 11 n_reviewed: 5 reviewed: - Tl - dl - pll - spz - tub - id: FBgg0001711 symbol: MEN name: MALIC ENZYMES n_members: 5 n_reviewed: 2 reviewed: - Men - Men-b - id: FBgg0001033 symbol: OXRCHCH2 name: CH OR CH2 GROUP OXIDOREDUCTASES n_members: 5 n_reviewed: 2 reviewed: - RnrL - RnrS - id: FBgg0000841 symbol: CNLIG-G name: CARBON-NITROGEN LIGASES, WITH GLUTAMINE AS AMIDO-N-DONOR n_members: 8 n_reviewed: 3 reviewed: - Asns - GatA - GatB - id: FBgg0000820 symbol: INTOC name: INTRAMOLECULAR OXIDOREDUCTASES TRANSPOSING C-C DOUBLE BONDS n_members: 11 n_reviewed: 4 reviewed: - CG4592 - CG4594 - CG4598 - Dci - id: FBgg0000507 symbol: S-HSP name: SMALL HEAT SHOCK PROTEINS n_members: 11 n_reviewed: 4 reviewed: - Hsp22 - Hsp23 - Hsp26 - Hsp27 - id: FBgg0001051 symbol: TLR name: TOLL RECEPTORS n_members: 9 n_reviewed: 3 reviewed: - 18w - Tl - Toll-7 - id: FBgg0000871 symbol: ALDLYA name: ALDEHYDE-LYASES n_members: 6 n_reviewed: 2 reviewed: - CG10184 - Shmt - id: FBgg0001030 symbol: FOXS name: FERROXIDASES n_members: 6 n_reviewed: 2 reviewed: - Fer1HCH - Fer3HCH - id: FBgg0000500 symbol: HSP90 name: HEAT SHOCK PROTEIN 90 CHAPERONES n_members: 3 n_reviewed: 1 reviewed: - Hsp83 - id: FBgg0001316 symbol: PGGLCNACT name: PROTEOGLYCAN N-ACETYLGLUCOSAMINYLTRANSFERASES n_members: 3 n_reviewed: 1 reviewed: - ttv - id: FBgg0000751 symbol: SIX name: SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS n_members: 3 n_reviewed: 1 reviewed: - so - id: FBgg0001404 symbol: A22P name: A22 ASPARTIC ENDOPEPTIDASES n_members: 3 n_reviewed: 1 reviewed: - Psn - id: FBgg0001554 symbol: TOPI name: DNA TOPOISOMERASES TYPE I n_members: 3 n_reviewed: 1 reviewed: - Top3beta - id: FBgg0000855 symbol: GH30 name: GLUCOSYLCERAMIDASES n_members: 3 n_reviewed: 1 reviewed: - CG33090 - id: FBgg0001271 symbol: NUDK name: NUCLEOSIDE DIPHOSPHATE KINASES n_members: 3 n_reviewed: 1 reviewed: - awd - id: FBgg0001332 symbol: CYDA name: CYTIDINE DEAMINASES n_members: 3 n_reviewed: 1 reviewed: - CG8353 - id: FBgg0001067 symbol: DSL name: NOTCH LIGANDS n_members: 3 n_reviewed: 1 reviewed: - Ser - id: FBgg0001257 symbol: NUTF-U name: UNCLASSIFIED NUCLEOTIDYLTRANSFERASES n_members: 3 n_reviewed: 1 reviewed: - PNPase - id: FBgg0002012 symbol: GBBH name: GAMMA-BUTYROBETAINE HYDROXYLASES n_members: 3 n_reviewed: 1 reviewed: - CG10814 - id: FBgg0000375 symbol: NR0 name: NUCLEAR RECEPTOR SUBFAMILY 0 (LIGAND-INDEPENDENT) TRANSCRIPTION FACTORS n_members: 3 n_reviewed: 1 reviewed: - kni - id: FBgg0000229 symbol: GSK name: GLYCOGEN SYNTHASE 3-LIKE KINASES n_members: 3 n_reviewed: 1 reviewed: - sgg - id: FBgg0001551 symbol: miRLC name: miRNA RISC LOADING COMPLEX n_members: 3 n_reviewed: 1 reviewed: - loqs - id: FBgg0000061 symbol: BCL2 name: BCL-2 FAMILY n_members: 3 n_reviewed: 1 reviewed: - Buffy - id: FBgg0001553 symbol: aRLC name: ALTERNATIVE siRNA RISC-LOADING COMPLEX n_members: 3 n_reviewed: 1 reviewed: - loqs - id: FBgg0001072 symbol: GPDHN name: GLYCEROL-3-PHOSPHATE DEHYDROGENASES (NAD+) n_members: 3 n_reviewed: 1 reviewed: - Gpdh3 - id: FBgg0001050 symbol: OXRPMOP name: MONOOXYGENASES, REDUCED PTERIDINE AS ONE DONOR n_members: 3 n_reviewed: 1 reviewed: - Hn - id: FBgg0001674 symbol: RNASEP-M name: MITOCHONDRIAL RNASE P COMPLEX n_members: 3 n_reviewed: 1 reviewed: - scu - id: FBgg0000740 symbol: PRDH name: PAIRED HOMEOBOX TRANSCRIPTION FACTORS n_members: 7 n_reviewed: 2 reviewed: - ey - toy - id: FBgg0000100 symbol: CASP name: CASPASES n_members: 7 n_reviewed: 2 reviewed: - Dcp-1 - Dronc - id: FBgg0002079 symbol: ECH name: ENOYL-COA HYDRATASES n_members: 7 n_reviewed: 2 reviewed: - Echs1 - Mtpalpha - id: FBgg0001024 symbol: DIOX-U name: UNCLASSIFIED DIOXYGENASES n_members: 8 n_reviewed: 2 reviewed: - Adi1 - CG30022 - id: FBgg0000286 symbol: NURF name: NUCLEOSOME REMODELING FACTOR n_members: 4 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0001658 symbol: SLC66 name: SLC66 FAMILY OF LYSOSOMAL AMINO ACID TRANSPORTERS n_members: 4 n_reviewed: 1 reviewed: - Ctns - id: FBgg0001073 symbol: IDH name: ISOCITRATE DEHYDROGENASES n_members: 4 n_reviewed: 1 reviewed: - Idh - id: FBgg0000959 symbol: EGFR-AG name: EGFR AGONISTS n_members: 4 n_reviewed: 1 reviewed: - spi - id: FBgg0000896 symbol: DES-C name: BETA CATENIN DESTRUCTION COMPLEX APC VARIANT n_members: 4 n_reviewed: 1 reviewed: - sgg - id: FBgg0000072 symbol: ADAM name: ADAM METALLOPROTEASES n_members: 4 n_reviewed: 1 reviewed: - kuz - id: FBgg0001809 symbol: DES-C2 name: BETA CATENIN DESTRUCTION COMPLEX APC2 VARIANT n_members: 4 n_reviewed: 1 reviewed: - sgg - id: FBgg0000227 symbol: STE7-MAPKK name: STE7 MAP KINASE KINASES n_members: 4 n_reviewed: 1 reviewed: - Dsor1 - id: FBgg0001382 symbol: KLG name: KLINGON SUBFAMILY OF WIRINS n_members: 4 n_reviewed: 1 reviewed: - klg - id: FBgg0000908 symbol: TORC2 name: TORC2 COMPLEX n_members: 4 n_reviewed: 1 reviewed: - Sin1 - id: FBgg0001710 symbol: LMDH name: L-MALATE DEHYDROGENASES n_members: 4 n_reviewed: 1 reviewed: - Mdh1 - id: FBgg0000722 symbol: DSCAM name: DOWN SYNDROME CELL-ADHESION MOLECULES n_members: 4 n_reviewed: 1 reviewed: - Dscam1 - id: FBgg0001141 symbol: PNP name: PURINE NUCLEOSIDE PHOSPHORYLASES n_members: 4 n_reviewed: 1 reviewed: - Mtap - id: FBgg0001202 symbol: AAKGT name: ACYL TO ALKYL ACYLTRANSFERASES n_members: 4 n_reviewed: 1 reviewed: - Acly - id: FBgg0001135 symbol: PENT-U name: UNCLASSIFIED PENTOSYLTRANSFERASES n_members: 4 n_reviewed: 1 reviewed: - Tgt - id: FBgg0001449 symbol: PCON name: PROPROTEIN CONVERTASES n_members: 4 n_reviewed: 1 reviewed: - amon - id: FBgg0001120 symbol: AAT-U name: UNCLASSIFIED ALKYL OR ARYL (OTHER THAN METHYL) TRANSFERASES n_members: 13 n_reviewed: 3 reviewed: - Dhps - Dph1 - Dph2 - id: FBgg0001123 symbol: TA name: TRANSAMINASES n_members: 15 n_reviewed: 3 reviewed: - Gfat1 - Got1 - Got2 - id: FBgg0000244 symbol: MAPK-C name: CONVENTIONAL MITOGEN ACTIVATED PROTEIN KINASES n_members: 5 n_reviewed: 1 reviewed: - rl - id: FBgg0001219 symbol: NEDD8T name: NEDD8 TRANSFERASES n_members: 5 n_reviewed: 1 reviewed: - Diap1 - id: FBgg0000733 symbol: GATA name: GATA TRANSCRIPTION FACTORS n_members: 5 n_reviewed: 1 reviewed: - pnr - id: FBgg0002098 symbol: PUDP name: PSEUDOURIDINE 5'-PHOSPHATASES n_members: 5 n_reviewed: 1 reviewed: - CG5565 - id: FBgg0001602 symbol: NDPASE name: NUCLEOSIDE DIPHOSPHATE PHOSPHATASES n_members: 5 n_reviewed: 1 reviewed: - NTPase - id: FBgg0001987 symbol: MUVB name: MUVB CORE SUBUNITS n_members: 5 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0001964 symbol: MCIA name: MITOCHONDRIAL COMPLEX I INTERMEDIATE ASSEMBLY COMPLEX n_members: 5 n_reviewed: 1 reviewed: - Egm - id: FBgg0000252 symbol: B-TUB name: BETA TUBULINS n_members: 5 n_reviewed: 1 reviewed: - betaTub97EF - id: FBgg0001153 symbol: HMFRT name: HYDROXYMETHYL-, FORMYL- AND RELATED TRANSFERASES n_members: 5 n_reviewed: 1 reviewed: - Shmt - id: FBgg0000280 symbol: PRC2 name: POLYCOMB REPRESSIVE COMPLEX 2, PCL VARIANT n_members: 5 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0000376 symbol: DYNA-C name: DYNACTIN COMPLEX n_members: 11 n_reviewed: 2 reviewed: - cpa - cpb - id: FBgg0001090 symbol: TKL-NR name: NON-RECEPTOR TKL KINASES n_members: 11 n_reviewed: 2 reviewed: - Raf - pll - id: FBgg0000927 symbol: OXRNAD-U name: UNCLASSIFIED CH-OH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR n_members: 30 n_reviewed: 5 reviewed: - CG18547 - G6pd - Mtpalpha - Pgd - Tdh - id: FBgg0000699 symbol: IMB name: BETA IMPORTINS n_members: 12 n_reviewed: 2 reviewed: - cdm - msk - id: FBgg0001109 symbol: TMR-U name: UNCLASSIFIED TRANSMEMBRANE RECEPTORS n_members: 12 n_reviewed: 2 reviewed: - N - ptc - id: FBgg0002039 symbol: MCV-AF name: MITOCHONDRIAL PROTON-TRANSPORTING ATP SYNTHASE COMPLEX ASSEMBLY FACTORS n_members: 6 n_reviewed: 1 reviewed: - CG34117 - id: FBgg0001052 symbol: SPZ name: SPATZLES n_members: 6 n_reviewed: 1 reviewed: - spz - id: FBgg0001986 symbol: MMC name: MYB-MUVB TRANSCRIPTIONAL ACTIVATION COMPLEX n_members: 6 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0000701 symbol: KEK name: KEKKONS n_members: 6 n_reviewed: 1 reviewed: - kek1 - id: FBgg0001861 symbol: PRC2-JJ name: POLYCOMB REPRESSIVE COMPLEX 2, JARID2-JING VARIANT n_members: 6 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0000819 symbol: INTOAK name: INTRAMOLECULAR OXIDOREDUCTASES INTERCONVERTING ALDOSES AND KETOSES n_members: 6 n_reviewed: 1 reviewed: - Mri1 - id: FBgg0001379 symbol: LPL name: LYSOPHOSPHOLIPASES n_members: 6 n_reviewed: 1 reviewed: - sws - id: FBgg0001985 symbol: TMAC name: TESTIS-SPECIFIC MEIOTIC ARREST COMPLEX n_members: 6 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0001467 symbol: 3-5-XDNASE name: 3'-5' DNA EXONUCLEASES n_members: 13 n_reviewed: 2 reviewed: - Rad9 - mre11 - id: FBgg0001822 symbol: OXRS-U name: UNCLASSIFIED SULFUR GROUP OXIDOREDUCTASES n_members: 7 n_reviewed: 1 reviewed: - Ccs - id: FBgg0000843 symbol: OCNLIG name: UNCLASSIFIED CARBON-NITROGEN LIGASES n_members: 7 n_reviewed: 1 reviewed: - Ass - id: FBgg0001043 symbol: MOOX-U name: UNCLASSIFIED MONOOXYGENASES n_members: 8 n_reviewed: 1 reviewed: - nero - id: FBgg0000044 symbol: TBX name: T-BOX TRANSCRIPTION FACTORS n_members: 8 n_reviewed: 1 reviewed: - Doc1 - id: FBgg0000275 symbol: NURD name: NUCLEOSOME REMODELING DEACETYLASE COMPLEX n_members: 8 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0000152 symbol: COP9 name: COP9 SIGNALOSOME COMPLEX n_members: 8 n_reviewed: 1 reviewed: - CSN5 - id: FBgg0001829 symbol: COP9-T name: COP9 SIGNALOSOME COMPLEX - TESTIS-SPECIFIC VARIANT n_members: 8 n_reviewed: 1 reviewed: - CSN5 - id: FBgg0001393 symbol: CNPD name: CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES n_members: 8 n_reviewed: 1 reviewed: - Pde4 - id: FBgg0000233 symbol: A-PK name: ATYPICAL PROTEIN KINASES n_members: 18 n_reviewed: 2 reviewed: - CG3631 - mei-41 - id: FBgg0000823 symbol: PUS name: PSEUDOURIDINE SYNTHASES n_members: 9 n_reviewed: 1 reviewed: - RluA-1 - id: FBgg0001983 symbol: DRM-R2 name: DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF2 VARIANT n_members: 9 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0001007 symbol: OXRSO name: SULFUR OXIDOREDUCTASES, OXYGEN AS ACCEPTOR n_members: 9 n_reviewed: 1 reviewed: - shop - id: FBgg0001285 symbol: ADTF-U name: UNCLASSIFIED ADENYLYLTRANSFERASES n_members: 9 n_reviewed: 1 reviewed: - Nmnat - id: FBgg0000867 symbol: AMIDLYA name: AMIDINE-LYASES n_members: 10 n_reviewed: 1 reviewed: - Argl - id: FBgg0000342 symbol: RASGEF name: RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS n_members: 10 n_reviewed: 1 reviewed: - Sos - id: FBgg0001609 symbol: AAH-U name: UNCLASSIFIED ACID ANHYDRIDE HYDROLASES n_members: 10 n_reviewed: 1 reviewed: - Datp - id: FBgg0000330 symbol: ARFGAP name: ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEINS n_members: 10 n_reviewed: 1 reviewed: - Git - id: FBgg0001982 symbol: DRM-R name: DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT n_members: 10 n_reviewed: 1 reviewed: - Caf1-55 - id: FBgg0001776 symbol: HPX name: HEME PEROXIDASES n_members: 10 n_reviewed: 1 reviewed: - CG42331 - id: FBgg0001295 symbol: GLCAT name: GLUCURONOSYLTRANSFERASES n_members: 11 n_reviewed: 1 reviewed: - ttv - id: FBgg0001394 symbol: PDH-U name: UNCLASSIFIED PHOSPHORIC DIESTER HYDROLASES n_members: 11 n_reviewed: 1 reviewed: - Pld - id: FBgg0000925 symbol: SD name: CH-OH STEROID DEHYDROGENASES n_members: 11 n_reviewed: 1 reviewed: - scu - id: FBgg0000248 symbol: PK-U name: UNCLASSIFIED CONVENTIONAL PROTEIN KINASE DOMAIN KINASES n_members: 36 n_reviewed: 3 reviewed: - IKKbeta - IKKepsilon - fu - id: FBgg0001610 symbol: MYO-M name: MYOSIN MOTORS n_members: 12 n_reviewed: 1 reviewed: - jar - id: FBgg0001325 symbol: GLCT-U name: UNCLASSIFIED GLUCOSYLTRANSFERASES n_members: 12 n_reviewed: 1 reviewed: - CG33090 - id: FBgg0000887 symbol: HLYA-U name: UNCLASSIFIED HYDRO-LYASES n_members: 12 n_reviewed: 1 reviewed: - CG11134 - id: FBgg0001591 symbol: DEAH name: DEAH-BOX RNA HELICASES n_members: 13 n_reviewed: 1 reviewed: - CG8915 - id: FBgg0001037 symbol: PRXN name: PEROXIREDOXINS n_members: 13 n_reviewed: 1 reviewed: - Prx4 - id: FBgg0000239 symbol: CDK name: CYCLIN DEPENDENT KINASES n_members: 13 n_reviewed: 1 reviewed: - Cdk12 - id: FBgg0000118 symbol: E3-HECT name: HECT UBIQUITIN LIGASES n_members: 14 n_reviewed: 1 reviewed: - Smurf - id: FBgg0001572 symbol: GTPASE-U name: UNCLASSIFIED GTPASES n_members: 14 n_reviewed: 1 reviewed: - CG18528 - id: FBgg0001588 symbol: DNAHEL-U name: UNCLASSIFIED DNA HELICASES n_members: 14 n_reviewed: 1 reviewed: - Suv3 - id: FBgg0001041 symbol: OXRPMO2O-U name: UNCLASSIFIED 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES n_members: 14 n_reviewed: 1 reviewed: - Tmlh - id: FBgg0000240 symbol: CAMK name: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASES n_members: 29 n_reviewed: 2 reviewed: - AMPKalpha - Lkb1 - id: FBgg0000727 symbol: BHLH name: BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS n_members: 59 n_reviewed: 4 reviewed: - Hand - SREBP - sima - tgo - id: FBgg0000324 symbol: RAS name: RAS GTPASES n_members: 15 n_reviewed: 1 reviewed: - Ras85D - id: FBgg0000695 symbol: SLC25 name: SLC25 FAMILY OF MITOCHONDRIAL TRANSPORTERS n_members: 48 n_reviewed: 3 reviewed: - Dic1 - Dic4 - sea - id: FBgg0000390 symbol: AARS-C name: CYTOPLASMIC AMINOACYL-TRNA SYNTHETASES n_members: 16 n_reviewed: 1 reviewed: - TyrRS - id: FBgg0001077 symbol: S1A-NPH name: S1A NON-PEPTIDASE HOMOLOGS n_members: 68 n_reviewed: 4 reviewed: - CG34171 - CG43124 - CG4793 - scaf - id: FBgg0000606 symbol: GH22 name: LYSOZYMES n_members: 17 n_reviewed: 1 reviewed: - LysB - id: FBgg0000241 symbol: AGC-U name: UNCLASSIFIED AGC KINASES n_members: 17 n_reviewed: 1 reviewed: - Pdk1 - id: FBgg0000220 symbol: RTK name: RECEPTOR TYROSINE KINASES n_members: 17 n_reviewed: 1 reviewed: - Egfr - id: FBgg0001477 symbol: 3-5-XRNASE name: 3'-5' RNA EXONUCLEASES n_members: 17 n_reviewed: 1 reviewed: - PNPase - id: FBgg0001149 symbol: RRNAMT name: RRNA METHYLTRANSFERASES n_members: 18 n_reviewed: 1 reviewed: - Mrm2 - id: FBgg0001808 symbol: PSEUK-U name: UNCLASSIFIED PSEUDOKINASES n_members: 18 n_reviewed: 1 reviewed: - Stlk - id: FBgg0000362 symbol: NR name: NUCLEAR RECEPTOR (LIGAND-DEPENDENT) TRANSCRIPTION FACTORS n_members: 18 n_reviewed: 1 reviewed: - ftz-f1 - id: FBgg0001567 symbol: TRGTP name: TRANSLATIONAL GTPASES n_members: 18 n_reviewed: 1 reviewed: - eRF3 - id: FBgg0000750 symbol: FOX name: FORK HEAD BOX TRANSCRIPTION FACTORS n_members: 19 n_reviewed: 1 reviewed: - jumu - id: FBgg0001108 symbol: RLIG-U name: UNCLASSIFIED RECEPTOR LIGANDS n_members: 21 n_reviewed: 1 reviewed: - hh - id: FBgg0001736 symbol: EDNASE-U name: UNCLASSIFIED DNA ENDONUCLEASES n_members: 21 n_reviewed: 1 reviewed: - mre11 - id: FBgg0002033 symbol: MCI-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY FACTORS n_members: 21 n_reviewed: 1 reviewed: - Egm - id: FBgg0000964 symbol: NEPL name: NEPRILYSIN-LIKE METALLOENDOPEPTIDASES n_members: 21 n_reviewed: 1 reviewed: - Nepl19 - id: FBgg0000256 symbol: HAD-NPP name: HAD FAMILY NON-PROTEIN PHOSPHATASES n_members: 21 n_reviewed: 1 reviewed: - Enoph - id: FBgg0001146 symbol: TRNAMT name: TRNA METHYLTRANSFERASES n_members: 22 n_reviewed: 1 reviewed: - Mettl1 - id: FBgg0001261 symbol: PCGTF-U name: UNCLASSIFIED PHOSPHORUS-CONTAINING GROUP TRANSFERASES n_members: 22 n_reviewed: 1 reviewed: - CG33116 - id: FBgg0001618 symbol: ECKL name: ECDYSTEROID KINASE-LIKE n_members: 51 n_reviewed: 2 reviewed: - CG31099 - CG6830 - id: FBgg0000255 symbol: PI-IPP name: PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES n_members: 26 n_reviewed: 1 reviewed: - Synj - id: FBgg0000336 symbol: RHOGEF name: RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS n_members: 27 n_reviewed: 1 reviewed: - Sos - id: FBgg0001600 symbol: ATPASE-U name: UNCLASSIFIED ATPASES n_members: 27 n_reviewed: 1 reviewed: - rad50 - id: FBgg0000150 symbol: FBXO name: F BOX ONLY PROTEINS n_members: 28 n_reviewed: 1 reviewed: - Fbxo42 - id: FBgg0000739 symbol: NKL name: NK-LIKE HOMEOBOX TRANSCRIPTION FACTORS n_members: 30 n_reviewed: 1 reviewed: - tin - id: FBgg0001079 symbol: SP-C name: S1A SERINE PROTEASES - CHYMOTRYPSIN-LIKE n_members: 61 n_reviewed: 2 reviewed: - CG17404 - CG30287 - id: FBgg0000128 symbol: E3-RING-U name: UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES n_members: 101 n_reviewed: 3 reviewed: - Kpc1 - mib1 - neur - id: FBgg0000774 symbol: DBDTF-U name: UNCLASSIFIED DNA BINDING DOMAIN TRANSCRIPTION FACTORS n_members: 38 n_reviewed: 1 reviewed: - dac - id: FBgg0001177 symbol: CLECT name: C-TYPE LECTIN-LIKE n_members: 40 n_reviewed: 1 reviewed: - rgn - id: FBgg0000573 symbol: TLNF-CIF name: CYTOPLASMIC TRANSLATION INITIATION FACTORS n_members: 41 n_reviewed: 1 reviewed: - eIF4E1 - id: FBgg0000504 symbol: HSP40 name: HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES n_members: 42 n_reviewed: 1 reviewed: - P58IPK - id: FBgg0001078 symbol: SP-T name: S1A SERINE PROTEASES - TRYPSIN-LIKE n_members: 114 n_reviewed: 2 reviewed: - CG30288 - CG43742 - id: FBgg0001176 symbol: CPR name: CPR CUTICLE PROTEIN FAMILY n_members: 103 n_reviewed: 1 reviewed: - Lcp3 - id: FBgg0000732 symbol: ZF-C2H2 name: C2H2 ZINC FINGER TRANSCRIPTION FACTORS n_members: 273 n_reviewed: 2 reviewed: - ci - dati group_detail: - id: FBgg0001189 symbol: GLUE name: GLUE PROTEINS members: - symbol: Eig71Ee uniprot: Q9VUS8 reviewed_in_repo: false go_annotations: - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:15544943 with_from: null label: puparial adhesion - qualifier: involved_in term: GO:0007594 evidence: ISS reference: PMID:8568884 with_from: FB:FBgn0003374 label: puparial adhesion - qualifier: involved_in term: GO:0042381 evidence: IDA reference: PMID:15544943 with_from: null label: hemolymph coagulation - qualifier: involved_in term: GO:0042381 evidence: IMP reference: PMID:18222466 with_from: null label: hemolymph coagulation - qualifier: located_in term: GO:0005576 evidence: IDA reference: PMID:15544943 with_from: null label: extracellular region - qualifier: located_in term: GO:0005576 evidence: IC reference: PMID:8253272 with_from: GO:0007594 label: extracellular region - qualifier: located_in term: GO:0005576 evidence: ISM reference: PMID:8568884 with_from: null label: extracellular region - qualifier: located_in term: GO:0062129 evidence: IDA reference: PMID:15544943 with_from: null label: chitin-based extracellular matrix - symbol: Sgs1 uniprot: Q9VR49 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:10511555 with_from: null label: puparial adhesion - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region - symbol: Sgs3 uniprot: P02840 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region - qualifier: located_in term: GO:0005576 evidence: IEA reference: GO_REF:0000044 with_from: UniProtKB-SubCell:SL-0243 label: extracellular region - symbol: Sgs4 uniprot: Q00725 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region - qualifier: located_in term: GO:0005576 evidence: IEA reference: GO_REF:0000044 with_from: UniProtKB-SubCell:SL-0243 label: extracellular region - symbol: Sgs5 uniprot: P07701 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region - symbol: Sgs5bis uniprot: Q9VEI6 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: ISS reference: GO_REF:0000024 with_from: UniProtKB:P07701 label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: ISS reference: PMID:30696414 with_from: UniProtKB:P07701 label: puparial adhesion - symbol: Sgs7 uniprot: P02841 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region - symbol: Sgs8 uniprot: P02842 reviewed_in_repo: false go_annotations: - qualifier: enables term: GO:0140073 evidence: EXP reference: PMID:825230 with_from: null label: bioadhesive activity - qualifier: involved_in term: GO:0007594 evidence: IEP reference: PMID:825230 with_from: null label: puparial adhesion - qualifier: is_active_in term: GO:0005576 evidence: IDA reference: PMID:825230 with_from: null label: extracellular region go_footprint: GO:0007594: label: puparial adhesion fly_genes_annotated: - Eig71Ee - Sgs1 - Sgs3 - Sgs4 - Sgs5 - Sgs5bis - Sgs7 - Sgs8 - Swip-1 not_in_group: - Swip-1 GO:0042381: label: hemolymph coagulation fly_genes_annotated: - Dmel\CG42259 - Eig71Ee - Glt - Hml - PPO1 - PPO2 - Tg - fon not_in_group: - Dmel\CG42259 - Glt - Hml - PPO1 - PPO2 - Tg - fon GO:0140073: label: bioadhesive activity fly_genes_annotated: - Sgs1 - Sgs3 - Sgs4 - Sgs5 - Sgs5bis - Sgs7 - Sgs8 not_in_group: []