release: fb_2026_03 n_groups: 2016 decision_counts: EXISTING_MODULE: 110 NEW_MODULE: 291 NOT_A_MODULE: 1324 REGULATOR_SET: 34 SUBSUMED: 231 UMBRELLA: 26 n_new_modules: 174 n_existing_modules: 68 groups: - id: FBgg0000040 symbol: E3-RBR name: RING-BETWEEN-RING UBIQUITIN LIGASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3 - id: FBgg0000041 symbol: GPCR-A name: CLASS A GPCRs source: gene_group n_members: 75 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR - id: FBgg0000042 symbol: R-SNARE name: R-SNAREs source: gene_group n_members: 5 decision: SUBSUMED module: snare_fusion_cycle inherited_from: SNARE - id: FBgg0000043 symbol: VSP4C name: VPS4-VTA1 COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT - id: FBgg0000044 symbol: TBX name: T-BOX TRANSCRIPTION FACTORS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: IG-TF - id: FBgg0000045 symbol: K2P name: TWO-PORE DOMAIN K[+] CHANNEL SUBUNITS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KCN - id: FBgg0000046 symbol: IFT name: INTRAFLAGELLAR TRANSPORT COMPLEXES source: gene_group n_members: 23 decision: NEW_MODULE module: dmel_intraflagellar_transport - id: FBgg0000047 symbol: VHA-ACS name: VACUOLAR ATPASE ACCESSORY SUBUNITS source: gene_group n_members: 4 decision: SUBSUMED module: dmel_vacuolar_atpase inherited_from: VHA - id: FBgg0000048 symbol: ILP name: INSULIN-LIKE PEPTIDES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000049 symbol: GPCR-B2 name: CLASS B GPCRs, SUBFAMILY B2 source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-B - id: FBgg0000050 symbol: SEA name: GATOR COMPLEXES source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_torc1_nutrient_sensing - id: FBgg0000051 symbol: CATCHR name: CATCHR COMPLEXES source: gene_group n_members: 21 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000052 symbol: ESCRT-0 name: ESCRT-0 COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT - id: FBgg0000053 symbol: QC-SNARE name: Qc-SNAREs source: gene_group n_members: 4 decision: SUBSUMED module: snare_fusion_cycle inherited_from: Q-SNARE - id: FBgg0000054 symbol: GPCR-F name: CLASS F GPCRs source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR - id: FBgg0000055 symbol: IR-ANT name: ANTENNAL IONOTROPIC RECEPTORS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IR - id: FBgg0000057 symbol: ESCRT-III name: ESCRT-III COMPLEX source: gene_group n_members: 8 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT - id: FBgg0000058 symbol: ITG name: INTEGRINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000059 symbol: MRP name: MITOCHONDRIAL RIBOSOMAL SUBUNITS source: gene_group n_members: 83 decision: NEW_MODULE module: dmel_mitochondrial_ribosome - id: FBgg0000060 symbol: SMC5-6-T name: SMC5/6 COMPLEX - QJT VARIANT source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_smc5_6_complex - id: FBgg0000061 symbol: BCL2 name: BCL-2 FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000062 symbol: E3-ROC name: ROC UBIQUITIN LIGASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000063 symbol: SMC-C name: SMC COMPLEXES source: gene_group n_members: 21 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000064 symbol: IAP name: INHIBITOR OF APOPTOSIS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000066 symbol: QB-SNARE name: Qb-SNAREs source: gene_group n_members: 5 decision: SUBSUMED module: snare_fusion_cycle inherited_from: Q-SNARE - id: FBgg0000067 symbol: I-SPN name: INHIBITORY SERPINS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: SPN - id: FBgg0000068 symbol: QA-SNARE name: Qa-SNAREs source: gene_group n_members: 8 decision: SUBSUMED module: snare_fusion_cycle inherited_from: Q-SNARE - id: FBgg0000069 symbol: E3 name: E3 UBIQUITIN LIGASES source: gene_group n_members: 154 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: UBT - id: FBgg0000070 symbol: RH name: RHODOPSINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-A - id: FBgg0000071 symbol: RPS name: CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT source: gene_group n_members: 39 decision: SUBSUMED module: dmel_cytoplasmic_ribosome inherited_from: CRP - id: FBgg0000072 symbol: ADAM name: ADAM METALLOPROTEASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MET - id: FBgg0000073 symbol: VHA-V1 name: VACUOLAR ATPASE V1 DOMAIN SUBUNITS source: gene_group n_members: 14 decision: SUBSUMED module: dmel_vacuolar_atpase inherited_from: VHA - id: FBgg0000074 symbol: APC name: ANAPHASE-PROMOTING COMPLEX source: gene_group n_members: 12 decision: NEW_MODULE module: dmel_anaphase_promoting_complex - id: FBgg0000075 symbol: IFT-A name: INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-A source: gene_group n_members: 5 decision: SUBSUMED module: dmel_intraflagellar_transport inherited_from: IFT - id: FBgg0000076 symbol: ATG name: AUTOPHAGY-RELATED GENES source: gene_group n_members: 20 decision: NEW_MODULE module: dmel_autophagosome_biogenesis - id: FBgg0000077 symbol: GST name: GLUTATHIONE S-TRANSFERASES source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAT - id: FBgg0000078 symbol: GABA-B name: GABA(B) RECEPTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-C - id: FBgg0000079 symbol: GUSTR name: GUSTATORY RECEPTORS source: gene_group n_members: 60 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CHEMOR - id: FBgg0000080 symbol: GOLG name: GOLGINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000081 symbol: SMC name: STRUCTURAL MAINTENANCE OF CHROMOSOMES GENE FAMILY source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0000082 symbol: GGA name: GOLGI-LOCALIZING, GAMMA-ADAPTIN EAR DOMAIN HOMOLOGY, ARF-BINDING PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SINGLE_GENE reason: Single-gene group; a module needs at least two parts. - id: FBgg0000083 symbol: SYT name: SYNAPTOTAGMINS & SYNAPTOTAGMIN-LIKE PROTEINS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000084 symbol: SNAP name: SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE FACTOR-ATTACHMENT PROTEINS source: gene_group n_members: 3 decision: EXISTING_MODULE module: snare_fusion_cycle - id: FBgg0000085 symbol: P2YR name: PURINE GPCRs source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-A - id: FBgg0000086 symbol: YLW name: YELLOW source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000087 symbol: COPI name: COAT PROTEIN COMPLEX I source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_copi_coat - id: FBgg0000088 symbol: MLC-CAM name: MYOSIN LIGHT CHAINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000089 symbol: TYRR name: TYRAMINE RECEPTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: AMR - id: FBgg0000090 symbol: FZ name: FRIZZLED-TYPE RECEPTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-F - id: FBgg0000091 symbol: AMR-ORPH name: ORPHAN AMINE RECEPTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: AMR - id: FBgg0000092 symbol: FBXL name: F BOX AND LEUCINE-RICH REPEAT PROTEINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: FBOX - id: FBgg0000093 symbol: FBXW name: F BOX AND WD DOMAIN PROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: FBOX - id: FBgg0000094 symbol: BBS name: BBSOME source: gene_group n_members: 7 decision: EXISTING_MODULE module: bbsome - id: FBgg0000095 symbol: ACHR name: ACETYLCHOLINE RECEPTORS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000096 symbol: RZZ name: RZZ COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_rzz_complex - id: FBgg0000097 symbol: OR name: ODORANT RECEPTORS source: gene_group n_members: 60 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CHEMOR - id: FBgg0000098 symbol: STON name: STONINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Stonin gene family. - id: FBgg0000099 symbol: GPCR-B name: CLASS B GPCRs source: gene_group n_members: 26 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR - id: FBgg0000100 symbol: CASP name: CASPASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0000101 symbol: ESCRT-I name: ESCRT-I COMPLEX source: gene_group n_members: 5 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT - id: FBgg0000103 symbol: SPN name: SERPINS source: gene_group n_members: 30 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000104 symbol: E3-GOL name: GOLIATH UBIQUITIN LIGASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000105 symbol: CDH name: CADHERINS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000106 symbol: VPS-C name: VPS-C COMPLEX SUBUNITS source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_hops_corvet_tethering - id: FBgg0000107 symbol: EXOC name: EXOCYST source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_exocyst - id: FBgg0000108 symbol: COND-II name: CONDENSIN II source: gene_group n_members: 4 decision: SUBSUMED module: dmel_condensin_complexes inherited_from: COND - id: FBgg0000109 symbol: Q-SNARE name: Q-SNAREs source: gene_group n_members: 20 decision: SUBSUMED module: snare_fusion_cycle inherited_from: SNARE - id: FBgg0000110 symbol: BLOC2 name: BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-2 source: gene_group n_members: 2 decision: SUBSUMED module: dmel_bloc_borc_complexes inherited_from: BLOC - id: FBgg0000111 symbol: VHA name: VACUOLAR ATPASE SUBUNITS source: gene_group n_members: 36 decision: NEW_MODULE module: dmel_vacuolar_atpase - id: FBgg0000112 symbol: INX name: INNEXINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMCAP - id: FBgg0000113 symbol: ARP name: ACTIN-RELATED PROTEINS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000114 symbol: NSF name: N-ETHYLMALEIMIDE-SENSITIVE FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0000115 symbol: TRAF name: TNF RECEPTOR ASSOCIATED FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000116 symbol: COPII name: COAT PROTEIN COMPLEX II source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_copii_coat - id: FBgg0000117 symbol: JOSD-DUB name: JOSEPHIN DEUBIQUITINASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0000118 symbol: E3-HECT name: HECT UBIQUITIN LIGASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3 - id: FBgg0000119 symbol: CHEMOR name: CHEMORECEPTORS source: gene_group n_members: 134 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGIC - id: FBgg0000120 symbol: IGLUR-NON-U name: UNCLASSIFIED NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGLUR - id: FBgg0000121 symbol: P24 name: P24 TRANSPORTERS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000122 symbol: BOSS name: BOSS-TYPE RECEPTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-C - id: FBgg0000123 symbol: CLATH name: CLATHRIN COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_clathrin_adaptor_coats - id: FBgg0000125 symbol: IR-PSD name: IONOTROPIC RECEPTOR PSEUDOGENES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Pseudogene family. - id: FBgg0000126 symbol: N-SPN name: NON-INHIBITORY SERPINS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: SPN - id: FBgg0000127 symbol: CPC name: CHROMOSOMAL PASSENGER COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_chromosomal_passenger_complex - id: FBgg0000128 symbol: E3-RING-U name: UNCLASSIFIED RING DOMAIN UBIQUITIN LIGASES source: gene_group n_members: 101 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000129 symbol: APOP name: APOPTOSOME source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_rhg_apoptosome_caspase_activation - id: FBgg0000130 symbol: RP name: RIBOSOMAL SUBUNITS source: gene_group n_members: 177 decision: UMBRELLA reason: Cytoplasmic and mitochondrial ribosomes are separate modules. - id: FBgg0000131 symbol: CUL name: CULLINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000132 symbol: ATG-PK name: ATG1 PROTEIN KINASE COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_autophagosome_biogenesis inherited_from: ATG-CPX - id: FBgg0000133 symbol: OCTR name: OCTOPAMINE RECEPTORS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: AMR - id: FBgg0000134 symbol: MTH name: METHUSELAH-TYPE RECEPTORS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-B - id: FBgg0000135 symbol: SMO name: SMOOTHENED-TYPE RECEPTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-F - id: FBgg0000136 symbol: AP3 name: ADAPTOR PROTEIN COMPLEX 3 source: gene_group n_members: 4 decision: SUBSUMED module: dmel_clathrin_adaptor_coats inherited_from: AP - id: FBgg0000137 symbol: E2 name: E2 UBIQUITIN CONJUGATING ENZYMES source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: UBT - id: FBgg0000138 symbol: ATAC name: ATAC COMPLEX source: gene_group n_members: 13 decision: SUBSUMED module: dmel_gcn5_acetyltransferase_complexes inherited_from: GCN5 - id: FBgg0000139 symbol: UCH-DUB name: UCH DEUBIQUITINASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0000140 symbol: IFT-B name: INTRAFLAGELLAR TRANSPORT SUBCOMPLEX-B source: gene_group n_members: 11 decision: SUBSUMED module: dmel_intraflagellar_transport inherited_from: IFT - id: FBgg0000141 symbol: CRP name: CYTOPLASMIC RIBOSOMAL SUBUNITS source: gene_group n_members: 94 decision: NEW_MODULE module: dmel_cytoplasmic_ribosome - id: FBgg0000142 symbol: IR-DIV name: DIVERGENT IONOTROPIC RECEPTORS source: gene_group n_members: 42 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IR - id: FBgg0000143 symbol: UEV name: UBIQUITIN E2 ENZYME VARIANTS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSENZ - id: FBgg0000144 symbol: IGLUR-NMDA name: NMDA IONOTROPIC GLUTAMATE RECEPTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGLUR - id: FBgg0000145 symbol: AP1 name: ADAPTOR PROTEIN COMPLEX 1 source: gene_group n_members: 4 decision: SUBSUMED module: dmel_clathrin_adaptor_coats inherited_from: AP - id: FBgg0000146 symbol: NPC name: NUCLEAR PORE COMPLEX source: gene_group n_members: 31 decision: NEW_MODULE module: dmel_nuclear_pore_complex - id: FBgg0000147 symbol: SM-T name: SM TRAFFICKING GENES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000148 symbol: IR name: IONOTROPIC RECEPTORS source: gene_group n_members: 60 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGLURS - id: FBgg0000149 symbol: TRAPP name: TRAPP COMPLEXES source: gene_group n_members: 13 decision: NEW_MODULE module: dmel_trapp_complexes - id: FBgg0000150 symbol: FBXO name: F BOX ONLY PROTEINS source: gene_group n_members: 28 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: FBOX - id: FBgg0000151 symbol: AP name: ADAPTOR PROTEIN COMPLEXES source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_clathrin_adaptor_coats - id: FBgg0000152 symbol: COP9 name: COP9 SIGNALOSOME COMPLEX source: gene_group n_members: 8 decision: SUBSUMED module: dmel_cop9_signalosome inherited_from: COP9-C - id: FBgg0000153 symbol: MCC name: MON1-CCZ1 COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_mon1_ccz1_complex - id: FBgg0000154 symbol: MRPS name: MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT source: gene_group n_members: 31 decision: SUBSUMED module: dmel_mitochondrial_ribosome inherited_from: MRP - id: FBgg0000155 symbol: GST-C name: SOLUBLE GLUTATHIONE S-TRANSFERASES source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GST - id: FBgg0000156 symbol: COHSN name: MITOTIC COHESIN COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_cohesin_complexes - id: FBgg0000157 symbol: FBOX name: F BOX PROTEINS source: gene_group n_members: 43 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000158 symbol: ARPC3A name: ACTIN-RELATED PROTEIN 2/3 COMPLEX ARPC3A VARIANT source: gene_group n_members: 7 decision: SUBSUMED module: dmel_arp2_3_complex inherited_from: ARPC-C - id: FBgg0000160 symbol: JAMM-DUB name: JAMM DEUBIQUITINASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DUB - id: FBgg0000161 symbol: AP2 name: ADAPTOR PROTEIN COMPLEX 2 source: gene_group n_members: 4 decision: SUBSUMED module: dmel_clathrin_adaptor_coats inherited_from: AP - id: FBgg0000162 symbol: WNT name: WNTs source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000163 symbol: BLOC name: BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEXES source: gene_group n_members: 12 decision: NEW_MODULE module: dmel_bloc_borc_complexes - id: FBgg0000164 symbol: ANX name: ANNEXINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000165 symbol: DUB name: DEUBIQUITINASES source: gene_group n_members: 44 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULPP - id: FBgg0000166 symbol: MYO name: MYOSINS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000167 symbol: COND name: CONDENSIN source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_condensin_complexes - id: FBgg0000168 symbol: QBC-SNARE name: Qbc-SNAREs source: gene_group n_members: 3 decision: SUBSUMED module: snare_fusion_cycle inherited_from: Q-SNARE - id: FBgg0000169 symbol: DRS name: DROSOMYCINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0000170 symbol: USP-DUB name: USP DEUBIQUITINASES source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0000171 symbol: DOPR name: DOPAMINE RECEPTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: AMR - id: FBgg0000172 symbol: GPCR name: G PROTEIN COUPLED RECEPTORS source: gene_group n_members: 117 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000173 symbol: COND-I name: CONDENSIN I source: gene_group n_members: 5 decision: SUBSUMED module: dmel_condensin_complexes inherited_from: COND - id: FBgg0000174 symbol: GPCR-B1 name: CLASS B GPCRs, SUBFAMILY B1 source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-B - id: FBgg0000175 symbol: OBP name: ODORANT BINDING PROTEINS source: gene_group n_members: 52 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000176 symbol: IGLUR name: IONOTROPIC GLUTAMATE RECEPTORS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGLURS - id: FBgg0000177 symbol: RHG name: RHG PROTEINS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_rhg_apoptosome_caspase_activation - id: FBgg0000178 symbol: AMR name: AMINE RECEPTORS source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-A - id: FBgg0000179 symbol: NPPH name: NEUROPEPTIDES source: gene_group n_members: 50 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000180 symbol: GPCR-C name: CLASS C GPCRs source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR - id: FBgg0000181 symbol: MRPL name: MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT source: gene_group n_members: 53 decision: SUBSUMED module: dmel_mitochondrial_ribosome inherited_from: MRP - id: FBgg0000182 symbol: E3-TRIM name: TRIM UBIQUITIN LIGASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000183 symbol: SKP1 name: SKP1 GENE FAMILY source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000184 symbol: ACT name: ACTINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0000185 symbol: BLOC1 name: BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-1 source: gene_group n_members: 8 decision: SUBSUMED module: dmel_bloc_borc_complexes inherited_from: BLOC - id: FBgg0000186 symbol: MGLUR name: METABOTROPIC GLUTAMATE RECEPTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-C - id: FBgg0000187 symbol: MACHR name: MUSCARINIC ACETYLCHOLINE RECEPTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: ACHR - id: FBgg0000188 symbol: SEPT name: SEPTINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0000189 symbol: VHA-V0 name: VACUOLAR ATPASE V0 DOMAIN SUBUNITS source: gene_group n_members: 18 decision: SUBSUMED module: dmel_vacuolar_atpase inherited_from: VHA - id: FBgg0000190 symbol: KIF name: KINESINS source: gene_group n_members: 24 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MMOT - id: FBgg0000191 symbol: E3-IAP name: INHIBITOR OF APOPTOSIS UBIQUITIN LIGASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000192 symbol: BLOC3 name: BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-3 source: gene_group n_members: 2 decision: SUBSUMED module: dmel_bloc_borc_complexes inherited_from: BLOC - id: FBgg0000193 symbol: E1 name: E1 UBIQUITIN-LIKE ACTIVATING ENZYMES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CSLIG - id: FBgg0000194 symbol: SNARE name: SNAREs source: gene_group n_members: 25 decision: EXISTING_MODULE module: snare_fusion_cycle - id: FBgg0000195 symbol: NPR name: CLASS A GPCR NEUROPEPTIDE AND PROTEIN HORMONE RECEPTORS source: gene_group n_members: 44 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-A - id: FBgg0000196 symbol: RETRO name: RETROMER COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_retromer - id: FBgg0000197 symbol: MTN name: METALLOTHIONEINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000198 symbol: LAM name: LAMINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: CSP - id: FBgg0000199 symbol: ATG-C name: ATG12-ATG5-ATG16 COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_autophagosome_biogenesis inherited_from: ATG-CPX - id: FBgg0000200 symbol: RPL name: CYTOPLASMIC LARGE RIBOSOMAL SUBUNIT source: gene_group n_members: 52 decision: SUBSUMED module: dmel_cytoplasmic_ribosome inherited_from: CRP - id: FBgg0000201 symbol: PPK name: PICKPOCKET ION CHANNELS source: gene_group n_members: 31 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NAC - id: FBgg0000202 symbol: NACHR name: NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNITS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: ACHR - id: FBgg0000203 symbol: E3-UBOX name: U-BOX UBIQUITIN LIGASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3-RING - id: FBgg0000204 symbol: NIMR name: NIMROD-TYPE RECEPTORS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: SCAVL - id: FBgg0000205 symbol: IR-COR name: ANTENNAL IONOTROPIC CO-RECEPTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IR - id: FBgg0000206 symbol: 5HTR name: 5-HYDROXYTRYPTAMINE (SEROTONIN) GPCRs source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: AMR - id: FBgg0000207 symbol: ESCRT-II name: ESCRT-II COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT - id: FBgg0000208 symbol: PSM name: PROTEASOME SUBUNITS source: gene_group n_members: 50 decision: NEW_MODULE module: dmel_proteasome - id: FBgg0000209 symbol: GPCR-C-U name: UNCLASSIFIED CLASS C GPCRs source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-C - id: FBgg0000210 symbol: KASH name: KASH DOMAIN GENES source: gene_group n_members: 2 decision: EXISTING_MODULE module: linc_complex - id: FBgg0000211 symbol: FLO name: FLOTILLINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000213 symbol: HP1 name: HETEROCHROMATIN PROTEIN 1 FAMILY source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000214 symbol: IGLURS name: IONOTROPIC GLUTAMATE RECEPTOR SUPERFAMILY source: gene_group n_members: 74 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGIC - id: FBgg0000215 symbol: ESCRT name: ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT source: gene_group n_members: 20 decision: NEW_MODULE module: dmel_escrt_machinery - id: FBgg0000216 symbol: ATG-CPX name: AUTOPHAGY-RELATED COMPLEXES source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_autophagosome_biogenesis - id: FBgg0000217 symbol: ATG-PI3K name: AUTOPHAGY-SPECIFIC PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_autophagosome_biogenesis inherited_from: ATG-CPX - id: FBgg0000218 symbol: STE11-MAPKKK name: STE11 MAP KINASE KINASE KINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STE - id: FBgg0000219 symbol: DYRK name: DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000220 symbol: RTK name: RECEPTOR TYROSINE KINASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TK - id: FBgg0000221 symbol: TK name: TYROSINE KINASES source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000222 symbol: CKI name: CK1 KINASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000223 symbol: PSEUK name: PSEUDOKINASES source: gene_group n_members: 41 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSENZ - id: FBgg0000224 symbol: RGC name: RECEPTOR GUANYLATE CYCLASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0000225 symbol: PAK name: P21-ACTIVATED KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STE20 - id: FBgg0000226 symbol: CMGC name: CMGC KINASES source: gene_group n_members: 34 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000227 symbol: STE7-MAPKK name: STE7 MAP KINASE KINASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STE - id: FBgg0000228 symbol: MAPK name: MITOGEN ACTIVATED PROTEIN KINASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000229 symbol: GSK name: GLYCOGEN SYNTHASE 3-LIKE KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000230 symbol: PKG name: PROTEIN KINASE G FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AGC - id: FBgg0000231 symbol: AGC name: AGC-KINASES source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000232 symbol: TKL name: TYROSINE KINASE-LIKE KINASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000233 symbol: A-PK name: ATYPICAL PROTEIN KINASES source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000234 symbol: PK name: PROTEIN KINASES source: gene_group n_members: 218 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0000235 symbol: SRPK name: SERINE-ARGININE PROTEIN KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000236 symbol: GCK name: GERMINAL CENTER KINASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STE20 - id: FBgg0000237 symbol: CMGC-U name: UNCLASSIFIED CMGC KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000238 symbol: STE20 name: STE20 KINASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STE - id: FBgg0000239 symbol: CDK name: CYCLIN DEPENDENT KINASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CMGC - id: FBgg0000240 symbol: CAMK name: CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASES source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000241 symbol: AGC-U name: UNCLASSIFIED AGC KINASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AGC - id: FBgg0000242 symbol: PKA name: PROTEIN KINASE A FAMILY source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AGC - id: FBgg0000243 symbol: STE name: STE KINASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000244 symbol: MAPK-C name: CONVENTIONAL MITOGEN ACTIVATED PROTEIN KINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MAPK - id: FBgg0000245 symbol: NON-RTK name: NON-RECEPTOR TYROSINE KINASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TK - id: FBgg0000246 symbol: PKC name: PROTEIN KINASE C FAMILY source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AGC - id: FBgg0000247 symbol: MAPK-A name: ATYPICAL MITOGEN ACTIVATED PROTEIN KINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MAPK - id: FBgg0000248 symbol: PK-U name: UNCLASSIFIED CONVENTIONAL PROTEIN KINASE DOMAIN KINASES source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PK - id: FBgg0000249 symbol: SCYL name: SCYL PSEUDOKINASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0000250 symbol: TUB name: TUBULINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: CSP - id: FBgg0000251 symbol: A-TUB name: ALPHA TUBULINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: TUB - id: FBgg0000252 symbol: B-TUB name: BETA TUBULINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: TUB - id: FBgg0000253 symbol: G-TUB name: GAMMA TUBULINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: TUB - id: FBgg0000254 symbol: LPP name: LIPID PHOSPHATE PHOSPHATASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000255 symbol: PI-IPP name: PHOSPHATIDYLINOSITOL PHOSPHATE AND INOSITOL PHOSPHATE PHOSPHATASES source: gene_group n_members: 26 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000256 symbol: HAD-NPP name: HAD FAMILY NON-PROTEIN PHOSPHATASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000257 symbol: RPTP name: RECEPTOR PROTEIN TYROSINE PHOSPHATASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTP - id: FBgg0000259 symbol: PPP name: PPP FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STP - id: FBgg0000260 symbol: PTP name: PROTEIN TYROSINE PHOSPHATASES source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPASE - id: FBgg0000261 symbol: HAD-PP name: HAD FAMILY PROTEIN PHOSPHATASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPASE - id: FBgg0000262 symbol: PPM name: PPM FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STP - id: FBgg0000263 symbol: STP-U name: UNCLASSIFIED PROTEIN SERINE/THREONINE PHOSPHATASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STP - id: FBgg0000264 symbol: PPASE name: PROTEIN PHOSPHATASES source: gene_group n_members: 84 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000265 symbol: DSP name: DUAL SPECIFICITY PROTEIN PHOSPHATASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTP - id: FBgg0000266 symbol: STP name: PROTEIN SERINE/THREONINE PHOSPHATASES source: gene_group n_members: 44 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPASE - id: FBgg0000267 symbol: CPTP name: CYTOSOLIC PROTEIN TYROSINE PHOSPHATASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTP - id: FBgg0000268 symbol: PHOSASE name: PHOSPHATASES source: gene_group n_members: 177 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0000269 symbol: BEST name: BESTROPHINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CACC - id: FBgg0000270 symbol: PHOS-U name: UNCLASSIFIED PHOSPHATASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000271 symbol: ESPL-C name: ENHANCER OF SPLIT GENE COMPLEX source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: GENE_CLUSTER reason: Genes grouped by genomic locus (gene complex), not by a shared molecular unit. - id: FBgg0000272 symbol: KMT name: PROTEIN-LYSINE N-METHYLTRANSFERASES source: gene_group n_members: 41 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-METH - id: FBgg0000273 symbol: PRC1 name: POLYCOMB REPRESSIVE COMPLEX 1, PSC VARIANT source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000274 symbol: SET name: SET DOMAIN LYSINE METHYLTRANSFERASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KMT - id: FBgg0000275 symbol: NURD name: NUCLEOSOME REMODELING DEACETYLASE COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_nurd_complex - id: FBgg0000276 symbol: PR-DUB name: POLYCOMB REPRESSIVE DEUBIQUITINASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000277 symbol: P-METH name: PROTEIN METHYLTRANSFERASES source: gene_group n_members: 64 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: METH - id: FBgg0000278 symbol: SIRT name: SIRTUIN LYSINE DEACETYLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0000279 symbol: RPD3-HDA1 name: RPD3/HDA1 LYSINE DEACETYLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0000280 symbol: PRC2 name: POLYCOMB REPRESSIVE COMPLEX 2, PCL VARIANT source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000281 symbol: BAP name: BRAHMA ASSOCIATED PROTEINS COMPLEX source: gene_group n_members: 11 decision: SUBSUMED module: dmel_brahma_complexes inherited_from: BRM - id: FBgg0000282 symbol: FACT name: FACT COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0000283 symbol: MSL name: MALE SPECIFIC LETHAL COMPLEX source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_msl_dosage_compensation_complex - id: FBgg0000284 symbol: REMOD-C name: CHROMATIN REMODELING COMPLEXES (ATP-DEPENDENT) source: gene_group n_members: 51 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000285 symbol: TRX-C name: TRX COMPLEX source: gene_group n_members: 7 decision: SUBSUMED module: dmel_compass_family_complexes inherited_from: COMP-C - id: FBgg0000286 symbol: NURF name: NUCLEOSOME REMODELING FACTOR source: gene_group n_members: 4 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0000287 symbol: TIP60 name: TIP60 COMPLEX source: gene_group n_members: 16 decision: NEW_MODULE module: dmel_tip60_complex - id: FBgg0000288 symbol: PRMT name: PROTEIN ARGININE N-METHYLTRANSFERASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-METH - id: FBgg0000289 symbol: PHORC name: PHO REPRESSIVE COMPLEX - PHO VARIANT source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000291 symbol: INO80 name: INO80 COMPLEX source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_ino80_complex - id: FBgg0000292 symbol: PBAP name: POLYBROMO-CONTAINING BRAHMA ASSOCIATED PROTEINS COMPLEX source: gene_group n_members: 12 decision: SUBSUMED module: dmel_brahma_complexes inherited_from: BRM - id: FBgg0000293 symbol: NORC name: NORC COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0000294 symbol: BRM name: BRAHMA COMPLEXES source: gene_group n_members: 15 decision: NEW_MODULE module: dmel_brahma_complexes - id: FBgg0000295 symbol: CAF-1 name: CHROMATIN ASSEMBLY FACTOR 1 source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_chromatin_assembly_factor_1 - id: FBgg0000296 symbol: COMP name: COMPASS COMPLEX source: gene_group n_members: 8 decision: SUBSUMED module: dmel_compass_family_complexes inherited_from: COMP-C - id: FBgg0000297 symbol: ACF name: ACF COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0000298 symbol: DRAF name: dRING-ASSOCIATED FACTORS COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000299 symbol: CHRAC name: CHROMATIN ACCESSIBILITY COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0000300 symbol: CHR-MOD-C name: CHROMATIN MODIFYING COMPLEXES source: gene_group n_members: 96 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000301 symbol: SP1-KLF name: SP1/KLF TRANSCRIPTION FACTORS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000302 symbol: SMYD name: SET AND MYND DOMAIN FAMILY source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KMT - id: FBgg0000303 symbol: TRXG-C name: TRITHORAX GROUP COMPLEXES source: gene_group n_members: 44 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000304 symbol: PCG-DNA name: POLYCOMB GROUP RECRUITERS/DNA-BINDING PROTEINS source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000305 symbol: SAGA name: SAGA COMPLEX source: gene_group n_members: 21 decision: SUBSUMED module: dmel_gcn5_acetyltransferase_complexes inherited_from: GCN5 - id: FBgg0000307 symbol: KDM name: HISTONE DEMETHYLASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000308 symbol: JMJC-KDM name: JMJC FAMILY HISTONE DEMETHYLASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KDM - id: FBgg0000309 symbol: PCG-C name: POLYCOMB GROUP RING FINGER COMPLEXES source: gene_group n_members: 19 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0000310 symbol: LSD1 name: LSD1 FAMILY HISTONE DEMETHYLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KDM - id: FBgg0000312 symbol: TORC name: TORC REMODELING COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0000313 symbol: COMP-C name: COMPASS-TYPE COMPLEXES source: gene_group n_members: 16 decision: NEW_MODULE module: dmel_compass_family_complexes - id: FBgg0000314 symbol: ISWI name: ISWI COMPLEXES source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_iswi_complexes - id: FBgg0000315 symbol: TRR name: TRR COMPLEX source: gene_group n_members: 10 decision: SUBSUMED module: dmel_compass_family_complexes inherited_from: COMP-C - id: FBgg0000316 symbol: TAC1 name: TRITHORAX ACETYLATION COMPLEX 1 source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_compass_family_complexes - id: FBgg0000317 symbol: KAT name: PROTEIN-LYSINE ACETYLTRANSFERASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NACTT - id: FBgg0000318 symbol: RAN name: RAN GTPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000319 symbol: RAB name: RAB GTPASES source: gene_group n_members: 33 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000320 symbol: RHO name: RHO GTPASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000321 symbol: RAG name: RAG GTPASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_torc1_nutrient_sensing - id: FBgg0000322 symbol: ARF name: ARF GTPASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000323 symbol: RAS-SF name: RAS GTPASE SUPERFAMILY source: gene_group n_members: 80 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0000324 symbol: RAS name: RAS GTPASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000325 symbol: RGK name: RGK GTPASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0000326 symbol: PASI name: PASIFLORA PROTEINS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000327 symbol: RAPGAP name: RAP-LIKE GTPASE ACTIVATING PROTEINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RASGAP - id: FBgg0000328 symbol: RHOGAP name: RHO GTPASE ACTIVATING PROTEINS source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GAP - id: FBgg0000329 symbol: RASGAP name: RAS GTPASE ACTIVATING PROTEINS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GAP - id: FBgg0000330 symbol: ARFGAP name: ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEINS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GAP - id: FBgg0000331 symbol: RABGAP name: RAB GTPASE ACTIVATING PROTEINS source: gene_group n_members: 25 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GAP - id: FBgg0000332 symbol: RANGAP name: RAN GTPASE ACTIVATING PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GAP - id: FBgg0000333 symbol: RAS-SF-GAP name: RAS SUPERFAMILY GTPASE ACTIVATING PROTEINS source: gene_group n_members: 67 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. - id: FBgg0000334 symbol: RASGAP-D name: RAS-LIKE GTPASE ACTIVATING PROTEINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RASGAP - id: FBgg0000335 symbol: GTF name: GENERAL TRANSCRIPTION FACTOR COMPLEXES source: gene_group n_members: 35 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000336 symbol: RHOGEF name: RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GEF - id: FBgg0000337 symbol: RABGEF-DENN name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - DENN DOMAIN source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RABGEF - id: FBgg0000338 symbol: RANGEF name: RAN GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GEF - id: FBgg0000339 symbol: RABGEF-U name: UNCLASSIFIED RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RABGEF - id: FBgg0000340 symbol: RABGEF name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GEF - id: FBgg0000341 symbol: RAS-SF-GEF name: RAS SUPERFAMILY GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 63 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. - id: FBgg0000342 symbol: RASGEF name: RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GEF - id: FBgg0000343 symbol: ARFGEF name: ARF GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RAS-SF-GEF - id: FBgg0000344 symbol: RABGEF-VSP9 name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - VPS9 DOMAIN source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RABGEF - id: FBgg0000345 symbol: RABGEF-C name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTOR COMPLEXES source: gene_group n_members: 16 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000347 symbol: TFIID name: TRANSCRIPTION FACTOR II D COMPLEX source: gene_group n_members: 17 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000348 symbol: TFIIE name: TRANSCRIPTION FACTOR II E COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000349 symbol: TFIIF name: TRANSCRIPTION FACTOR II F COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000350 symbol: TFIIH name: TRANSCRIPTION FACTOR II H HOLOENZYME COMPLEX source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000351 symbol: RNAPII name: RNA POLYMERASE II source: gene_group n_members: 13 decision: SUBSUMED module: dmel_nuclear_rna_polymerases inherited_from: RNAP - id: FBgg0000352 symbol: T-TAF name: TESTIS-SPECIFIC TBP-ASSOCIATED FACTORS source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000353 symbol: TRF name: TATA-BINDING PROTEIN AND TBP-RELATED FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000354 symbol: CAK-XPD name: CDK-ACTIVATING KINASE-XERODERMA PIGMENTOSUM D COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000355 symbol: TFIIA name: TRANSCRIPTION FACTOR II A COMPLEXES source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_rnapii_general_transcription_factors - id: FBgg0000356 symbol: CAK name: CDK-ACTIVATING KINASE COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_rnapii_general_transcription_factors inherited_from: TFIIH - id: FBgg0000357 symbol: TFIIH-C name: TRANSCRIPTION FACTOR II H - CORE COMPLEX source: gene_group n_members: 7 decision: SUBSUMED module: dmel_rnapii_general_transcription_factors inherited_from: TFIIH - id: FBgg0000358 symbol: TRP name: TRANSIENT RECEPTOR POTENTIAL ION CHANNELS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0000359 symbol: MED name: MEDIATOR CORE COMPLEX source: gene_group n_members: 26 decision: SUBSUMED module: dmel_mediator_complex inherited_from: MEDC - id: FBgg0000362 symbol: NR name: NUCLEAR RECEPTOR (LIGAND-DEPENDENT) TRANSCRIPTION FACTORS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZNC4 - id: FBgg0000363 symbol: HOX-C name: HOX GENE COMPLEX source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: GENE_CLUSTER reason: Genes grouped by genomic locus (gene complex), not by a shared molecular unit. - id: FBgg0000364 symbol: DYN name: DYNEIN SUBUNITS source: gene_group n_members: 34 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0000365 symbol: ANT-C name: ANTENNAPEDIA COMPLEX source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: GENE_CLUSTER reason: Genes grouped by genomic locus (gene complex), not by a shared molecular unit. inherited_from: HOX-C - id: FBgg0000366 symbol: BX-C name: BITHORAX COMPLEX source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: GENE_CLUSTER reason: Genes grouped by genomic locus (gene complex), not by a shared molecular unit. inherited_from: HOX-C - id: FBgg0000367 symbol: TRNA-C name: CYTOSOLIC TRANSFER RNAS source: gene_group n_members: 295 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA - id: FBgg0000368 symbol: AARS name: AMINOACYL-TRNA SYNTHETASES source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLIG - id: FBgg0000375 symbol: NR0 name: NUCLEAR RECEPTOR SUBFAMILY 0 (LIGAND-INDEPENDENT) TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZNC4 - id: FBgg0000376 symbol: DYNA-C name: DYNACTIN COMPLEX source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_cytoplasmic_dynein_dynactin - id: FBgg0000377 symbol: DYN-HC name: DYNEIN HEAVY CHAINS source: gene_group n_members: 13 decision: UMBRELLA reason: Subunit-type or assembly-factor category; children are triaged individually. - id: FBgg0000378 symbol: DYNC name: CYTOPLASMIC DYNEIN HEAVY CHAINS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_cytoplasmic_dynein_dynactin - id: FBgg0000379 symbol: DYNA name: AXONEMAL DYNEIN HEAVY CHAINS source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000380 symbol: DYN-OAD name: AXONEMAL OUTER ARM DYNEIN HEAVY CHAINS source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000381 symbol: DYN-IAD name: AXONEMAL INNER ARM DYNEIN HEAVY CHAINS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000382 symbol: DYN-LC name: DYNEIN LIGHT CHAINS source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_cytoplasmic_dynein_dynactin - id: FBgg0000383 symbol: DYN-LIC name: DYNEIN LIGHT INTERMEDIATE CHAINS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_cytoplasmic_dynein_dynactin - id: FBgg0000384 symbol: DYN-IC name: DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 8 decision: UMBRELLA reason: Subunit-type or assembly-factor category; children are triaged individually. - id: FBgg0000385 symbol: DYNC-IC name: CYTOPLASMIC DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 1 decision: NEW_MODULE module: dmel_cytoplasmic_dynein_dynactin - id: FBgg0000386 symbol: DYNA-IC name: AXONEMAL DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000387 symbol: DYNOA-IC name: AXONEMAL OUTER ARM DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000388 symbol: DYNIA-IC name: AXONEMAL INNER ARM DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_axonemal_dynein_arms - id: FBgg0000389 symbol: SDIC name: SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000390 symbol: AARS-C name: CYTOPLASMIC AMINOACYL-TRNA SYNTHETASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AARS - id: FBgg0000391 symbol: AARS-M name: MITOCHONDRIAL AMINOACYL-TRNA SYNTHETASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AARS - id: FBgg0000392 symbol: AARS-DL name: DUAL-LOCALIZED AMINOACYL-TRNA SYNTHETASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AARS - id: FBgg0000393 symbol: TRNA-C-ALA name: CYTOSOLIC ALANINE TRANSFER RNAS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000394 symbol: TRNA-C-ARG name: CYTOSOLIC ARGININE TRANSFER RNAS source: gene_group n_members: 26 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000395 symbol: TRNA-C-ASN name: CYTOSOLIC ASPARAGINE TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000396 symbol: TRNA-C-ASP name: CYTOSOLIC ASPARTIC ACID TRANSFER RNAS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000397 symbol: TRNA-C-CYS name: CYTOSOLIC CYSTEINE TRANSFER RNAS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000398 symbol: TRNA-C-GLN name: CYTOSOLIC GLUTAMINE TRANSFER RNAS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000399 symbol: TRNA-C-GLU name: CYTOSOLIC GLUTAMIC ACID TRANSFER RNAS source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000400 symbol: TRNA-C-GLY name: CYTOSOLIC GLYCINE TRANSFER RNAS source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000401 symbol: TRNA-C-HIS name: CYTOSOLIC HISTIDINE TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000402 symbol: TRNA-C-ILE name: CYTOSOLIC ISOLEUCINE TRANSFER RNAS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000403 symbol: TRNA-C-LEU name: CYTOSOLIC LEUCINE TRANSFER RNAS source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000404 symbol: TRNA-C-LYS name: CYTOSOLIC LYSINE TRANSFER RNAS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000405 symbol: TRNA-C-MET name: CYTOSOLIC METHIONINE TRANSFER RNAS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000406 symbol: TRNA-C-PHE name: CYTOSOLIC PHENYLALANINE TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000407 symbol: TRNA-C-PRO name: CYTOSOLIC PROLINE TRANSFER RNAS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000408 symbol: TRNA-C-SEC name: CYTOSOLIC SELENOCYSTEINE TRANSFER RNAS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000409 symbol: TRNA-C-SER name: CYTOSOLIC SERINE TRANSFER RNAS source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000410 symbol: TRNA-C-THR name: CYTOSOLIC THREONINE TRANSFER RNAS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000411 symbol: TRNA-C-TRP name: CYTOSOLIC TRYPTOPHAN TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000412 symbol: TRNA-C-TYR name: CYTOSOLIC TYROSINE TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000413 symbol: TRNA-C-VAL name: CYTOSOLIC VALINE TRANSFER RNAS source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C - id: FBgg0000414 symbol: TRNA-C-ALA-AGC name: CYTOSOLIC ALANINE-AGC TRANSFER RNAS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ALA - id: FBgg0000415 symbol: TRNA-C-ALA-CGC name: CYTOSOLIC ALANINE-CGC TRANSFER RNAS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ALA - id: FBgg0000416 symbol: TRNA-C-ALA-TGC name: CYTOSOLIC ALANINE-TGC TRANSFER RNAS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ALA - id: FBgg0000417 symbol: TRNA-C-ARG-ACG name: CYTOSOLIC ARGININE-ACG TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ARG - id: FBgg0000418 symbol: TRNA-C-ARG-TCG name: CYTOSOLIC ARGININE-TCG TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ARG - id: FBgg0000419 symbol: TRNA-C-ARG-CCT name: CYTOSOLIC ARGININE-CCT TRANSFER RNAS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ARG - id: FBgg0000420 symbol: TRNA-C-ARG-TCT name: CYTOSOLIC ARGININE-TCT TRANSFER RNAS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ARG - id: FBgg0000421 symbol: TRNA-C-ASN-GTT name: CYTOSOLIC ASPARAGINE-GTT TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ASN - id: FBgg0000422 symbol: TRNA-C-ASP-GTC name: CYTOSOLIC ASPARTIC ACID-GTC TRANSFER RNAS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ASP - id: FBgg0000423 symbol: TRNA-C-CYS-GCA name: CYTOSOLIC CYSTEINE-GCA TRANSFER RNAS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-CYS - id: FBgg0000424 symbol: TRNA-C-GLN-CTG name: CYTOSOLIC GLUTAMINE-CTG TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLN - id: FBgg0000425 symbol: TRNA-C-GLN-TTG name: CYTOSOLIC GLUTAMINE-TTG TRANSFER RNAS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLN - id: FBgg0000426 symbol: TRNA-C-GLU-CTC name: CYTOSOLIC GLUTAMIC ACID-CTC TRANSFER RNAS source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLU - id: FBgg0000427 symbol: TRNA-C-GLU-TTC name: CYTOSOLIC GLUTAMIC ACID-TTC TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLU - id: FBgg0000428 symbol: TRNA-C-GLY-GCC name: CYTOSOLIC GLYCINE-GCC TRANSFER RNAS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLY - id: FBgg0000429 symbol: TRNA-C-GLY-TCC name: CYTOSOLIC GLYCINE-TCC TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-GLY - id: FBgg0000430 symbol: TRNA-C-HIS-GTG name: CYTOSOLIC HISTIDINE-GTG TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-HIS - id: FBgg0000431 symbol: TRNA-C-ILE-AAT name: CYTOSOLIC ISOLEUCINE-AAT TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ILE - id: FBgg0000432 symbol: TRNA-C-ILE-TAT name: CYTOSOLIC ISOLEUCINE-TAT TRANSFER RNAS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-ILE - id: FBgg0000433 symbol: TRNA-C-LEU-AAG name: CYTOSOLIC LEUCINE-AAG TRANSFER RNAS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LEU - id: FBgg0000434 symbol: TRNA-C-LEU-CAG name: CYTOSOLIC LEUCINE-CAG TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LEU - id: FBgg0000435 symbol: TRNA-C-LEU-TAG name: CYTOSOLIC LEUCINE-TAG TRANSFER RNAS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LEU - id: FBgg0000436 symbol: TRNA-C-LEU-CAA name: CYTOSOLIC LEUCINE-CAA TRANSFER RNAS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LEU - id: FBgg0000437 symbol: TRNA-C-LEU-TAA name: CYTOSOLIC LEUCINE-TAA TRANSFER RNAS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LEU - id: FBgg0000438 symbol: TRNA-C-LYS-CTT name: CYTOSOLIC LYSINE-CTT TRANSFER RNAS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LYS - id: FBgg0000439 symbol: TRNA-C-LYS-TTT name: CYTOSOLIC LYSINE-TTT TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-LYS - id: FBgg0000440 symbol: TRNA-C-MET-CAT name: CYTOSOLIC METHIONINE-CAT TRANSFER RNAS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-MET - id: FBgg0000441 symbol: TRNA-C-PHE-GAA name: CYTOSOLIC PHENYLALANINE-GAA TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-PHE - id: FBgg0000442 symbol: TRNA-C-PRO-AGG name: CYTOSOLIC PROLINE-AGG TRANSFER RNAS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-PRO - id: FBgg0000443 symbol: TRNA-C-PRO-CGG name: CYTOSOLIC PROLINE-CGG TRANSFER RNAS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-PRO - id: FBgg0000444 symbol: TRNA-C-PRO-TGG name: CYTOSOLIC PROLINE-TGG TRANSFER RNAS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-PRO - id: FBgg0000445 symbol: TRNA-C-SEC-TCA name: CYTOSOLIC SELENOCYSTEINE-TCA TRANSFER RNAS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-SEC - id: FBgg0000446 symbol: TRNA-C-SER-AGA name: CYTOSOLIC SERINE-AGA TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-SER - id: FBgg0000447 symbol: TRNA-C-SER-CGA name: CYTOSOLIC SERINE-CGA TRANSFER RNAS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-SER - id: FBgg0000448 symbol: TRNA-C-SER-TGA name: CYTOSOLIC SERINE-TGA TRANSFER RNAS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-SER - id: FBgg0000449 symbol: TRNA-C-SER-GCT name: CYTOSOLIC SERINE-GCT TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-SER - id: FBgg0000450 symbol: TRNA-C-THR-AGT name: CYTOSOLIC THREONINE-AGT TRANSFER RNAS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-THR - id: FBgg0000451 symbol: TRNA-C-THR-CGT name: CYTOSOLIC THREONINE-CGT TRANSFER RNAS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-THR - id: FBgg0000452 symbol: TRNA-C-THR-TGT name: CYTOSOLIC THREONINE-TGT TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-THR - id: FBgg0000453 symbol: TRNA-C-TRP-CCA name: CYTOSOLIC TRYPTOPHAN-CCA TRANSFER RNAS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-TRP - id: FBgg0000454 symbol: TRNA-C-TYR-GTA name: CYTOSOLIC TYROSINE-GTA TRANSFER RNAS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-TYR - id: FBgg0000455 symbol: TRNA-C-VAL-AAC name: CYTOSOLIC VALINE-AAC TRANSFER RNAS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-VAL - id: FBgg0000456 symbol: TRNA-C-VAL-CAC name: CYTOSOLIC VALINE-CAC TRANSFER RNAS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-VAL - id: FBgg0000457 symbol: TRNA-C-VAL-TAC name: CYTOSOLIC VALINE-TAC TRANSFER RNAS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA-C-VAL - id: FBgg0000458 symbol: G-SUB name: HETEROTRIMERIC G-PROTEIN SUBUNITS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000459 symbol: TRNA name: TRANSFER RNAS source: gene_group n_members: 317 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. - id: FBgg0000460 symbol: TRNA-MT name: MITOCHONDRIAL TRANSFER RNAS source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: NONCODING_CLASS reason: tRNA gene classes grouped by anticodon. inherited_from: TRNA - id: FBgg0000461 symbol: PEX name: PEROXINS source: gene_group n_members: 16 decision: EXISTING_MODULE module: peroxisome-lifecycle - id: FBgg0000462 symbol: SMN-C name: SURVIVAL MOTOR NEURON COMPLEX - GEM4A VARIANT source: gene_group n_members: 5 decision: SUBSUMED module: dmel_smn_complex inherited_from: SMN-CPX - id: FBgg0000463 symbol: G-SUB-A name: HETEROTRIMERIC G-PROTEIN ALPHA SUBUNITS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: G-SUB - id: FBgg0000464 symbol: G-SUB-B name: HETEROTRIMERIC G-PROTEIN BETA SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: G-SUB - id: FBgg0000465 symbol: G-SUB-G name: HETEROTRIMERIC G-PROTEIN GAMMA SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: G-SUB - id: FBgg0000466 symbol: GARP name: GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_garp_complex - id: FBgg0000467 symbol: COG name: CONSERVED OLIGOMERIC GOLGI COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_cog_complex - id: FBgg0000469 symbol: CCR4-NOT name: CCR4-NOT COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_ccr4_not_complex - id: FBgg0000470 symbol: GEM name: GEMINS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_smn_complex - id: FBgg0000471 symbol: GARPI name: GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEX I source: gene_group n_members: 4 decision: SUBSUMED module: dmel_garp_complex inherited_from: GARP - id: FBgg0000472 symbol: GARPII name: GOLGI-ASSOCIATED RETROGRADE PROTEIN COMPLEX II source: gene_group n_members: 4 decision: SUBSUMED module: dmel_garp_complex inherited_from: GARP - id: FBgg0000473 symbol: DGC name: DYSTROPHIN GLYCOPROTEIN COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_dystrophin_glycoprotein_complex - id: FBgg0000474 symbol: NEP name: NEPRILYSINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: M13 - id: FBgg0000475 symbol: MET name: METZINCINS source: gene_group n_members: 24 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0000476 symbol: ADAMTS name: ADAM WITH THROMBOSPONDIN MOTIF source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MET - id: FBgg0000479 symbol: SYN name: SYNTROPHINS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_dystrophin_glycoprotein_complex - id: FBgg0000480 symbol: DYS-REL name: DYSTROPHIN-RELATED PROTEINS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_dystrophin_glycoprotein_complex - id: FBgg0000481 symbol: SCG name: SARCOGLYCANS source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_dystrophin_glycoprotein_complex - id: FBgg0000482 symbol: OXPHOS name: MITOCHONDRIAL OXPHOS COMPLEX SUBUNITS source: gene_group n_members: 93 decision: EXISTING_MODULE module: oxphos - id: FBgg0000483 symbol: MCV-F1 name: MITOCHONDRIAL COMPLEX V - F1 SUBUNITS source: gene_group n_members: 7 decision: SUBSUMED module: mitochondrial_complex_v inherited_from: MCV - id: FBgg0000484 symbol: MCIII name: MITOCHONDRIAL COMPLEX III SUBUNITS source: gene_group n_members: 14 decision: EXISTING_MODULE module: mitochondrial_complex_iii - id: FBgg0000485 symbol: MCII-SDH name: MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) SUBUNITS source: gene_group n_members: 7 decision: EXISTING_MODULE module: mitochondrial_complex_ii - id: FBgg0000486 symbol: ETF name: ELECTRON TRANSFER FLAVOPROTEIN COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: electron_transfer_flavoprotein_system - id: FBgg0000487 symbol: MCI name: MITOCHONDRIAL COMPLEX I SUBUNITS source: gene_group n_members: 50 decision: EXISTING_MODULE module: mitochondrial_complex_i_core - id: FBgg0000488 symbol: MCIV name: MITOCHONDRIAL COMPLEX IV SUBUNITS source: gene_group n_members: 22 decision: EXISTING_MODULE module: mitochondrial_complex_iv - id: FBgg0000489 symbol: MCV-F0 name: MITOCHONDRIAL COMPLEX V - F0 SUBUNITS source: gene_group n_members: 17 decision: SUBSUMED module: mitochondrial_complex_v inherited_from: MCV - id: FBgg0000490 symbol: CYT-C name: CYTOCHROME C source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000491 symbol: MCV name: MITOCHONDRIAL COMPLEX V SUBUNITS source: gene_group n_members: 24 decision: EXISTING_MODULE module: mitochondrial_complex_v - id: FBgg0000492 symbol: WRC name: WAVE REGULATORY COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_wave_regulatory_complex - id: FBgg0000493 symbol: WASP name: WISKOTT-ALDRICH SYNDROME PROTEINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000494 symbol: S-CHTO name: STABILIN-1 INTERACTING CHITOLECTINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: GH18 - id: FBgg0000496 symbol: GH18 name: GLYCOSIDE HYDROLASE FAMILY 18 source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000497 symbol: HSP70 name: HEAT SHOCK PROTEIN 70 CHAPERONES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000498 symbol: HSP70-A name: ATYPICAL HEAT SHOCK PROTEIN 70 CHAPERONES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000499 symbol: KV-A name: VOLTAGE-GATED POTASSIUM CHANNEL - ALPHA SUBUNITS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KV - id: FBgg0000500 symbol: HSP90 name: HEAT SHOCK PROTEIN 90 CHAPERONES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000501 symbol: HSP name: HEAT SHOCK PROTEINS source: gene_group n_members: 86 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. - id: FBgg0000502 symbol: HSP60-I name: HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP I source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP60 - id: FBgg0000503 symbol: HSP60 name: HEAT SHOCK PROTEIN 60 CHAPERONINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000504 symbol: HSP40 name: HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES source: gene_group n_members: 42 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000505 symbol: CCT name: CHAPERONIN CONTAINING TCP-1 COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_cct_chaperonin - id: FBgg0000506 symbol: KV name: VOLTAGE-GATED POTASSIUM CHANNEL SUBUNITS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KCN - id: FBgg0000507 symbol: S-HSP name: SMALL HEAT SHOCK PROTEINS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0000508 symbol: WASH-C name: WASP AND SCAR HOMOLOG COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_wash_complex - id: FBgg0000509 symbol: IRK name: INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KCN - id: FBgg0000510 symbol: ORC name: ORIGIN RECOGNITION COMPLEX source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_replication_origin_licensing_activation - id: FBgg0000511 symbol: CHT name: CHITINASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: GH18 - id: FBgg0000512 symbol: KCN name: POTASSIUM CHANNEL SUBUNITS source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0000513 symbol: KV-B name: VOLTAGE-GATED POTASSIUM CHANNEL - BETA SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KV - id: FBgg0000514 symbol: IDGF name: IMAGINAL DISC GROWTH FACTORS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: GH18 - id: FBgg0000515 symbol: GC name: GUANYLATE CYCLASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: POLYA - id: FBgg0000516 symbol: SGC name: SOLUBLE GUANYLATE CYCLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GC - id: FBgg0000517 symbol: SGC-A name: SOLUBLE GUANYLATE CYCLASES ATYPICAL source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GC - id: FBgg0000518 symbol: OATP name: SLC21 FAMILY OF ORGANIC ANION TRANSPORTING POLYPEPTIDES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000519 symbol: SPL-C name: SPLICEOSOMAL COMPLEXES source: gene_group n_members: 146 decision: NEW_MODULE module: dmel_spliceosome - id: FBgg0000520 symbol: SNRNP name: SPLICEOSOMAL SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLES source: gene_group n_members: 69 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-C - id: FBgg0000521 symbol: U1 name: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 17 decision: SUBSUMED module: dmel_spliceosome inherited_from: SNRNP - id: FBgg0000522 symbol: U2 name: U2 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 25 decision: SUBSUMED module: dmel_spliceosome inherited_from: SNRNP - id: FBgg0000523 symbol: U4-U6 name: U4-U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 18 decision: SUBSUMED module: dmel_spliceosome inherited_from: SNRNP - id: FBgg0000524 symbol: U5 name: U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 22 decision: SUBSUMED module: dmel_spliceosome inherited_from: SNRNP - id: FBgg0000525 symbol: U4-U6-U5 name: U4-U6-U5 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 42 decision: SUBSUMED module: dmel_spliceosome inherited_from: SNRNP - id: FBgg0000526 symbol: SM name: SPLICEOSOMAL SM PROTEINS source: gene_group n_members: 7 decision: SUBSUMED module: dmel_spliceosome inherited_from: SM-ALL - id: FBgg0000527 symbol: UPD name: UNPAIRED FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000528 symbol: HCN name: HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KV - id: FBgg0000529 symbol: DPR name: DEFECTIVE PROBOSCIS EXTENSION RESPONSE source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: WRN - id: FBgg0000530 symbol: DIP name: DPR-INTERACTING PROTEINS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: WRN - id: FBgg0000531 symbol: TM9SF name: NONASPANINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000532 symbol: TSP name: TETRASPANINS source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000533 symbol: GAT1 name: GATOR1 COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_torc1_nutrient_sensing inherited_from: SEA - id: FBgg0000534 symbol: GAT2 name: GATOR2 COMPLEX source: gene_group n_members: 5 decision: SUBSUMED module: dmel_torc1_nutrient_sensing inherited_from: SEA - id: FBgg0000535 symbol: SPL-C-A name: SPLICEOSOME COMPLEX A source: gene_group n_members: 50 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-INT - id: FBgg0000536 symbol: SPL-C-C name: SPLICEOSOME COMPLEX C source: gene_group n_members: 91 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-INT - id: FBgg0000537 symbol: SPL-INT name: SPLICEOSOME COMPLEX INTERMEDIATES source: gene_group n_members: 145 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-C - id: FBgg0000538 symbol: U2AF name: U2 SNRNP AUXILIARY FACTOR source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_spliceosome - id: FBgg0000539 symbol: SPL-C-B name: SPLICEOSOME COMPLEX B source: gene_group n_members: 91 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-INT - id: FBgg0000540 symbol: ABCG name: ABCG ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000541 symbol: ABCB-AHT name: ABCB ATP-BINDING CASSETTE TRANSPORTER ATM SUBFAMILY - HALF TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABCB - id: FBgg0000542 symbol: ABC-NT name: ATP-BINDING CASSETTE TRANSPORTER-LIKE - NON-TRANSPORTING source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-TL - id: FBgg0000543 symbol: ABCD name: ABCD ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000544 symbol: ABCA name: ABCA ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000545 symbol: ABCB name: ABCB ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000546 symbol: ABCF name: ABCF ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-NT - id: FBgg0000547 symbol: ABC-T name: ATP-BINDING CASSETTE TRANSPORTERS source: gene_group n_members: 52 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-TL - id: FBgg0000548 symbol: ABCC name: ABCC ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000549 symbol: ABCE name: ABCE ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-NT - id: FBgg0000550 symbol: ABCH name: ABCH ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABC-T - id: FBgg0000551 symbol: ABCB-FT name: ABCB ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY - FULL TRANSPORTERS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABCB - id: FBgg0000552 symbol: ABC-TL name: ATP-BINDING CASSETTE TRANSPORTER-LIKE source: gene_group n_members: 56 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000553 symbol: CLC name: CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 26 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0000554 symbol: GLU-CL name: GLUTAMATE-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGCC - id: FBgg0000555 symbol: ANO name: ANOCTAMINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CACC - id: FBgg0000556 symbol: GABA-CL name: GABA-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGCC - id: FBgg0000557 symbol: CL-VG-U name: UNCLASSIFIED VOLTAGE-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CL-VG - id: FBgg0000558 symbol: CACC name: CALCIUM-ACTIVATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CLC - id: FBgg0000559 symbol: LGCC name: LIGAND-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CLC - id: FBgg0000560 symbol: TWE name: TWEETY FAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CACC - id: FBgg0000561 symbol: PH-CL name: PH-SENSITIVE CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGCC - id: FBgg0000562 symbol: CLC-F name: CLC PLASMA MEMBRANE CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CL-VG - id: FBgg0000563 symbol: HIS-CL name: HISTAMINE-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGCC - id: FBgg0000564 symbol: CL-VG name: VOLTAGE-GATED CHLORIDE CHANNEL SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CLC - id: FBgg0000566 symbol: CLIC name: INTRACELLULAR CHLORIDE CHANNEL FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CLC - id: FBgg0000567 symbol: TLNF name: TRANSLATION FACTORS source: gene_group n_members: 66 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors - id: FBgg0000568 symbol: UB name: UBIQUITIN source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0000569 symbol: SLP-C-P name: SPLICEOSOME COMPLEX P source: gene_group n_members: 86 decision: SUBSUMED module: dmel_spliceosome inherited_from: SPL-INT - id: FBgg0000570 symbol: GLURII name: NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGLUR - id: FBgg0000571 symbol: TLNF-C name: CYTOPLASMIC TRANSLATION FACTORS source: gene_group n_members: 55 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF - id: FBgg0000572 symbol: TLNF-M name: MITOCHONDRIAL TRANSLATION FACTORS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF - id: FBgg0000573 symbol: TLNF-CIF name: CYTOPLASMIC TRANSLATION INITIATION FACTORS source: gene_group n_members: 41 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-C - id: FBgg0000574 symbol: TLNF-CEF name: CYTOPLASMIC TRANSLATION ELONGATION FACTORS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-C - id: FBgg0000575 symbol: TLNF-CRF name: CYTOPLASMIC TRANSLATION RELEASE FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-C - id: FBgg0000576 symbol: TLNF-CRRF name: CYTOPLASMIC TRANSLATION RECYCLING AND REINITIATION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-C - id: FBgg0000577 symbol: TLNF-MIF name: MITOCHONDRIAL TRANSLATION INITIATION FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-M - id: FBgg0000578 symbol: TLNF-MEF name: MITOCHONDRIAL TRANSLATION ELONGATION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-M - id: FBgg0000579 symbol: TLNF-MRF name: MITOCHONDRIAL TRANSLATION RELEASE FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-M - id: FBgg0000580 symbol: TLNF-MRRF name: MITOCHONDRIAL TRANSLATION RECYCLING FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Translation factors grouped by stage of translation; they act as separate factors inherited_from: TLNF-M - id: FBgg0000581 symbol: LGIC name: LIGAND-GATED ION CHANNELS source: gene_group n_members: 236 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: GIC - id: FBgg0000582 symbol: IC name: ION CHANNELS source: gene_group n_members: 384 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMCAP - id: FBgg0000583 symbol: NAV-A name: VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NAV - id: FBgg0000584 symbol: PIEZO name: PIEZO ION CHANNELS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0000585 symbol: NAC name: SODIUM CHANNEL SUBUNITS source: gene_group n_members: 37 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0000586 symbol: NSCC name: NON-SELECTIVE CATION CHANNEL SUBUNITS source: gene_group n_members: 110 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0000587 symbol: NAV-B name: VOLTAGE-GATED SODIUM CHANNEL BETA SUBUNITS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NAV - id: FBgg0000588 symbol: CAC-U name: UNCLASSIFIED CALCIUM CHANNEL-FORMING SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0000589 symbol: ICC name: ION CHANNELS BY CONDUCTANCE source: gene_group n_members: 308 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IC - id: FBgg0000590 symbol: SC name: SODIUM CHANNEL-LIKE CATION CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0000591 symbol: CACN name: VOLTAGE-GATED CALCIUM CHANNEL PORE SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CACN-SU - id: FBgg0000592 symbol: CRAC name: CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_crac_channel_complex - id: FBgg0000593 symbol: CAC name: CALCIUM CHANNEL SUBUNITS source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0000594 symbol: SIDE name: SIDE FAMILY source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000595 symbol: NAV name: VOLTAGE-GATED SODIUM CHANNEL SUBUNITS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NAC - id: FBgg0000596 symbol: BEAT name: BEAT FAMILY source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000597 symbol: RNA-EXO name: NUCLEAR EXOSOME COMPLEX source: gene_group n_members: 10 decision: SUBSUMED module: dmel_rna_exosome inherited_from: RNAEXO - id: FBgg0000598 symbol: PGRP-S name: SHORT PEPTIDOGLYCAN RECOGNITION PROTEINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: PGRP - id: FBgg0000599 symbol: ELG1-C name: ELG1 COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_elg1_rfc_like_complex - id: FBgg0000600 symbol: PGRP-L name: LONG PEPTIDOGLYCAN RECOGNITION PROTEINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: PGRP - id: FBgg0000601 symbol: THO-C name: THO COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_mrna_nuclear_export - id: FBgg0000602 symbol: PGRP name: PEPTIDOGLYCAN RECOGNITION PROTEINS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000603 symbol: TREX name: TRANSCRIPTION EXPORT COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_mrna_nuclear_export - id: FBgg0000604 symbol: ENOK-C name: ENOK COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_enok_complex - id: FBgg0000605 symbol: TREX-2 name: TRANSCRIPTION EXPORT COMPLEX-2 source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_mrna_nuclear_export - id: FBgg0000606 symbol: GH22 name: LYSOZYMES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0000607 symbol: TZ name: TRANSITION ZONE COMPONENTS source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_ciliary_transition_zone - id: FBgg0000608 symbol: MKS name: MKS COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_ciliary_transition_zone - id: FBgg0000609 symbol: CEP290C name: CEP290 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_ciliary_transition_zone - id: FBgg0000612 symbol: OSI name: OSIRIS source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000613 symbol: GPI-ET-II name: GLYCOSYLPHOSPHATIDYLINOSITOL ETHANOLAMINE-PHOSPHATE TRANSFERASE II COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: gpi_anchor_ethanolamine_phosphate - id: FBgg0000614 symbol: NF-KB name: NUCLEAR FACTOR - KAPPA B source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: RHD - id: FBgg0000615 symbol: HCC name: HISTONE PRE-MRNA CLEAVAGE COMPLEX source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_histone_mrna_3prime_processing - id: FBgg0000616 symbol: GPI-TA name: GLYCOSYLPHOSPHATIDYLINOSITOL TRANSAMIDASE COMPLEX source: gene_group n_members: 5 decision: EXISTING_MODULE module: gpi_anchor_transamidase - id: FBgg0000617 symbol: PIG name: PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS GENES source: gene_group n_members: 26 decision: EXISTING_MODULE module: gpi_anchor_core_glycan_assembly - id: FBgg0000618 symbol: PF name: POLYADENYLATION FACTORS source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_cleavage_polyadenylation - id: FBgg0000619 symbol: PLA2 name: PHOSPHOLIPASES A2 source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0000620 symbol: GPI-ET-III name: GLYCOSYLPHOSPHATIDYLINOSITOL ETHANOLAMINE-PHOSPHATE TRANSFERASE III COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: gpi_anchor_ethanolamine_phosphate - id: FBgg0000621 symbol: CCC name: CORE CLEAVAGE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_cleavage_polyadenylation - id: FBgg0000622 symbol: GPI-MT-I name: GLYCOSYLPHOSPHATIDYLINOSITOL MANNOSYLTRANSFERASE I COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: gpi_anchor_core_glycan_assembly - id: FBgg0000623 symbol: PIG-CPX name: PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS COMPLEXES source: gene_group n_members: 15 decision: EXISTING_MODULE module: gpi_anchor_core_glycan_assembly - id: FBgg0000624 symbol: IPLA2 name: PHOSPHOLIPASE A2 ENZYMES - CALCIUM INDEPENDENT source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PLA2 - id: FBgg0000626 symbol: PROT name: PROTAMINES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000627 symbol: SPLA2 name: PHOSPHOLIPASE A2 ENZYMES - SECRETED source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PLA2 - id: FBgg0000628 symbol: U7 name: U7 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_histone_mrna_3prime_processing - id: FBgg0000629 symbol: GPI-GNT name: GLYCOSYLPHOSPHATIDYLINOSITOL-N-ACETYLGLUCOSAMINYLTRANSFERASE COMPLEX source: gene_group n_members: 5 decision: EXISTING_MODULE module: gpi_anchor_glcnac_transferase - id: FBgg0000630 symbol: HPF name: HISTONE MRNA 3' END PROCESSING FACTORS source: gene_group n_members: 20 decision: NEW_MODULE module: dmel_histone_mrna_3prime_processing - id: FBgg0000631 symbol: SNURPS name: SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLES source: gene_group n_members: 77 decision: NEW_MODULE module: dmel_spliceosome - id: FBgg0000632 symbol: SM-ALL name: SM PROTEINS source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_spliceosome - id: FBgg0000633 symbol: PI-K name: PHOSPHATIDYLINOSITOL KINASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LK - id: FBgg0000634 symbol: IPK name: INOSITOL PHOSPHATE KINASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0000635 symbol: GK name: GLYCEROL KINASE source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: GK-L - id: FBgg0000636 symbol: PGK name: PSEUDO-GLYCEROL KINASE source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0000637 symbol: DGK name: DIACYLGLYCEROL KINASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LK - id: FBgg0000638 symbol: CERK name: CERAMIDE KINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LK - id: FBgg0000639 symbol: LK name: LIPID KINASES source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0000640 symbol: SK name: SPHINGOSINE KINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LK - id: FBgg0000641 symbol: GK-L name: GLYCEROL KINASE-LIKE source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000642 symbol: SAQP name: S-AQUAPORINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: WCP - id: FBgg0000643 symbol: AQGP name: AQUAGLYCEROPORINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: WCP - id: FBgg0000644 symbol: NATA name: N-TERMINAL ACETYLTRANSFERASE A COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_n_terminal_acetyltransferase_complexes inherited_from: NAT-CPX - id: FBgg0000645 symbol: AQP name: AQUAPORINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: WCP - id: FBgg0000646 symbol: TSF name: TRANSFERRINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000647 symbol: U7-SM name: U7 SM PROTEINS source: gene_group n_members: 7 decision: SUBSUMED module: dmel_spliceosome inherited_from: SM-ALL - id: FBgg0000648 symbol: NATB name: N-TERMINAL ACETYLTRANSFERASE B COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_n_terminal_acetyltransferase_complexes inherited_from: NAT-CPX - id: FBgg0000649 symbol: FER name: FERRITINS source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_ferritin_complex - id: FBgg0000650 symbol: NAT-CPX name: N-TERMINAL ACETYLTRANSFERASE COMPLEXES source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_n_terminal_acetyltransferase_complexes - id: FBgg0000651 symbol: NAT name: N-TERMINAL ACETYLTRANSFERASE CATALYTIC SUBUNITS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: NAA - id: FBgg0000652 symbol: WCP name: WATER CHANNEL PROTEINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMCAP - id: FBgg0000653 symbol: NATC name: N-TERMINAL ACETYLTRANSFERASE C COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_n_terminal_acetyltransferase_complexes inherited_from: NAT-CPX - id: FBgg0000654 symbol: MCO name: MULTICOPPER OXIDASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000655 symbol: NAA name: N-TERMINAL ACETYLTRANSFERASE SUBUNITS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000656 symbol: NAX name: N-TERMINAL ACETYLTRANSFERASE AUXILIARY SUBUNITS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: NAA - id: FBgg0000657 symbol: SLC44 name: SLC44 CHOLINE TRANSPORTER-LIKE FAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000658 symbol: SLC45 name: SLC45 FAMILY OF SUCROSE TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000659 symbol: SLC46 name: SLC46 FOLATE TRANSPORTER-LIKE FAMILY source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000660 symbol: SLC38 name: SLC38 FAMILY OF SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000661 symbol: SLC8 name: SLC8 FAMILY OF SODIUM/CALCIUM EXCHANGERS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000662 symbol: SLC7 name: SLC7 FAMILY OF AMINO ACID TRANSPORTERS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000663 symbol: SLC26 name: SLC26 FAMILY OF ANION EXCHANGERS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000664 symbol: SLC3 name: SLC3 FAMILY OF HETEROMERIC AMINO ACID TRANSPORTERS ANCILLARY SUBUNITS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000665 symbol: SLC30 name: SLC30 FAMILY OF ZINC TRANSPORTERS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000666 symbol: SLC15 name: SLC15 FAMILY OF PEPTIDE TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000667 symbol: SLC22 name: SLC22 FAMILY OF ORGANIC IONS TRANSPORTERS source: gene_group n_members: 41 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000668 symbol: SLC41 name: SLC41 FAMILY OF MAGNESIUM ION TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000669 symbol: SLC16 name: SLC16 FAMILY OF MONOCARBOXYLATE TRANSPORTERS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000670 symbol: SLC1 name: SLC1 FAMILY OF GLUTAMATE AND NEUTRAL AMINO ACID TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000671 symbol: SLC36 name: SLC36 FAMILY OF PROTON-COUPLED AMINO ACID TRANSPORTERS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000672 symbol: SLC32 name: SLC32 FAMILY OF VESICULAR GABA TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000673 symbol: SLC24 name: SLC24 FAMILY OF POTASSIUM-DEPENDENT SODIUM/CALCIUM EXCHANGERS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000674 symbol: SLC29 name: SLC29 FAMILY OF EQUILIBRATIVE NUCLEOSIDE TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000675 symbol: SLC18 name: SLC18 FAMILY OF VESICULAR NEUROTRANSMITTER TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000676 symbol: SLC13 name: SLC13 FAMILY OF DICARBOXYLATE/CITRATE TRANSPORTERS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000677 symbol: SLC9 name: SLC9 FAMILY OF SODIUM/PROTON EXCHANGERS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000678 symbol: SLC28 name: SLC28 FAMILY OF CONCENTRATIVE NUCLEOSIDE CO-TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000679 symbol: SLC39 name: SLC39 FAMILY OF ZINC ION TRANSPORTERS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000680 symbol: SLC6 name: SLC6 FAMILY OF SODIUM/CHLORIDE-DEPENDENT NEUROTRANSMITTER TRANSPORTERS source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000681 symbol: SLC5 name: SLC5 FAMILY OF SODIUM-DEPENDENT SOLUTE TRANSPORTERS source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000682 symbol: SLC12 name: SLC12 FAMILY OF CATION-COUPLED CHLORIDE TRANSPORTERS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000683 symbol: SLC11 name: SLC11 FAMILY OF PROTON-COUPLED METAL ION TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000684 symbol: CAT name: CATIONIC AMINO ACID TRANSPORTERS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC7 - id: FBgg0000685 symbol: SLC35 name: SLC35 FAMILY OF NUCLEOTIDE SUGAR TRANSPORTERS source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000686 symbol: SLC name: TRANSMEMBRANE CARRIER PROTEINS source: gene_group n_members: 405 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMT - id: FBgg0000687 symbol: SLC37 name: SLC37 FAMILY OF PHOSPHOSUGAR/PHOSPHATE EXCHANGERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000688 symbol: SLC27 name: SLC27 FAMILY OF FATTY ACID TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000689 symbol: SLC4 name: SLC4 FAMILY OF BICARBONATE TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000690 symbol: SLC50 name: SLC50 FAMILY OF SUGAR TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000691 symbol: SLC2 name: SLC2 FAMILY OF HEXOSE SUGAR TRANSPORTERS source: gene_group n_members: 31 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000692 symbol: SLC20 name: SLC20 FAMILY OF SODIUM/PHOSPHATE CO-TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000693 symbol: LAT name: L-TYPE AMINO ACID TRANSPORTERS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC7 - id: FBgg0000694 symbol: SLC19 name: SLC19 FAMILY OF VITAMIN TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000695 symbol: SLC25 name: SLC25 FAMILY OF MITOCHONDRIAL TRANSPORTERS source: gene_group n_members: 48 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC25-MP - id: FBgg0000696 symbol: SLC31 name: SLC31 FAMILY OF COPPER TRANSPORTERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000697 symbol: SLC33 name: SLC33 ACETYL-COA TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000698 symbol: SLC17 name: SLC17 FAMILY OF ORGANIC ANION TRANSPORTERS source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0000699 symbol: IMB name: BETA IMPORTINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: IM - id: FBgg0000700 symbol: ATP-NK name: NA[+]/K[+] TRANSPORTING P-ATPASE SUBUNITS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: P-TMT - id: FBgg0000701 symbol: KEK name: KEKKONS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000702 symbol: MTC name: M6A METHYLTRANSFERASE COMPLEX source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_m6a_methyltransferase_complex - id: FBgg0000703 symbol: IM name: IMPORTINS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000704 symbol: SEMA name: SEMAPHORINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000705 symbol: IMA name: ALPHA IMPORTINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: IM - id: FBgg0000706 symbol: ATPIIA name: SARCO(ENDO)PLASMIC RETICULUM CALCIUM TRANSPORTING P-ATPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0000707 symbol: ATPIV name: PHOSPHOLIPID TRANSPORTING ATPASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0000708 symbol: 14-3-3 name: 14-3-3 PROTEINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000709 symbol: P-ATPASE name: P-TYPE ATPASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASETT - id: FBgg0000710 symbol: COMML name: COMMISSURELESS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000711 symbol: ATPIB name: COPPER TRANSPORTING P-ATPASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0000712 symbol: ATPIIC name: NA[+]/K[+] TRANSPORTING P-ATPASE - ALPHA SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ATP-NK - id: FBgg0000713 symbol: ATPB name: NA[+]/K[+] TRANSPORTING P-ATPASE - BETA SUBUNITS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ATP-NK - id: FBgg0000714 symbol: NTN name: NETRINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000716 symbol: ROBO name: ROUNDABOUT source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000717 symbol: ATPV name: TYPE V P-ATPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0000718 symbol: PLXN name: PLEXINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000719 symbol: ATPIIB name: PLASMA MEMBRANE CALCIUM TRANSPORTING P-ATPASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0000720 symbol: ELBA name: ELBA BOUNDARY FACTOR COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_elba_boundary_complex - id: FBgg0000721 symbol: BOM name: BOMANINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0000722 symbol: DSCAM name: DOWN SYNDROME CELL-ADHESION MOLECULES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0000723 symbol: PO name: PHENOLOXIDASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRDPO - id: FBgg0000724 symbol: CNPY name: CANOPY CO-CHAPERONES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000725 symbol: MCUNI name: MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_mitochondrial_calcium_uniporter inherited_from: MCU-CPXS - id: FBgg0000726 symbol: BZIP name: BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: BDTF - id: FBgg0000727 symbol: BHLH name: BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS source: gene_group n_members: 59 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: BDTF - id: FBgg0000728 symbol: BDTF name: BASIC DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 80 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000729 symbol: ZN-TF name: ZINC FINGER TRANSCRIPTION FACTORS source: gene_group n_members: 303 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000730 symbol: ZNC4 name: C4 ZINC FINGER TRANSCRIPTION FACTORS source: gene_group n_members: 26 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZN-TF - id: FBgg0000731 symbol: DMRT name: DMRT TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZN-TF - id: FBgg0000732 symbol: ZF-C2H2 name: C2H2 ZINC FINGER TRANSCRIPTION FACTORS source: gene_group n_members: 273 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZN-TF - id: FBgg0000733 symbol: GATA name: GATA TRANSCRIPTION FACTORS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: ZNC4 - id: FBgg0000734 symbol: TALE name: TALE HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000735 symbol: PRD name: PAIRED DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: PRDTF - id: FBgg0000736 symbol: TEATF name: TEA DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000737 symbol: LIM name: LIM HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000738 symbol: PRDTF name: PAIRED TRANSCRIPTION FACTORS source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000739 symbol: NKL name: NK-LIKE HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 30 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000740 symbol: PRDH name: PAIRED HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: PRDTF - id: FBgg0000741 symbol: CUT name: CUT HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000742 symbol: PROS name: PROSPERO HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000743 symbol: PRDL name: PAIRED-LIKE HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000744 symbol: HBTF name: HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 102 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000745 symbol: TFS name: TRANSCRIPTION FACTORS source: gene_group n_members: 631 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. - id: FBgg0000746 symbol: HTH name: HELIX-TURN-HELIX TRANSCRIPTION FACTORS source: gene_group n_members: 146 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000747 symbol: HOXL name: HOX-LIKE HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000748 symbol: HMGBTF name: HIGH MOBILITY GROUP BOX TRANSCRIPTION FACTORS source: gene_group n_members: 24 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000749 symbol: ZFH name: ZINC FINGER HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000750 symbol: FOX name: FORK HEAD BOX TRANSCRIPTION FACTORS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000751 symbol: SIX name: SINE OCULIS HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000752 symbol: POU name: POU HOMEOBOX TRANSCRIPTION FACTORS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HBTF - id: FBgg0000753 symbol: MADSTF name: MADS-BOX TRANSCRIPTION FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000754 symbol: MADF-BESS name: MADF-BESS DOMAIN PROTEINS source: gene_group n_members: 45 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000755 symbol: SANT-MYB-TR name: SANT-MYB DOMAIN TRANSCRIPTION REGULATORS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: SANT-MYB - id: FBgg0000756 symbol: RHD name: REL HOMOLOGY DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: IG-TF - id: FBgg0000757 symbol: MADF-BESS-TR name: MADF-BESS DOMAIN TRANSCRIPTION REGULATORS source: gene_group n_members: 42 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: MADF-BESS - id: FBgg0000758 symbol: ARID-TF name: A-T RICH INTERACTION DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000759 symbol: SANT-MYB-TF name: SANT-MYB DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000760 symbol: SANT-MYB name: SANT-MYB DOMAIN PROTEINS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000761 symbol: NFAT name: NUCLEAR FACTOR OF ACTIVATED T-CELLS TRANSCRIPTION FACTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: RHD - id: FBgg0000762 symbol: IG-TF name: IMMUNOGLOBULIN FOLD TRANSCRIPTION FACTORS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000763 symbol: MADF-BESS-TF name: MADF-BESS DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000764 symbol: ARID name: A-T RICH INTERACTION DOMAIN PROTEINS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000765 symbol: GCM name: GLIAL CELL MISSING TRANSCRIPTION FACTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000766 symbol: RUNT name: RUNT DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: SUBSUMED module: dmel_core_binding_factor inherited_from: CBF - id: FBgg0000767 symbol: ARID-TR name: A-T RICH INTERACTION DOMAIN TRANSCRIPTION REGULATORS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ARID - id: FBgg0000768 symbol: CBFB name: CORE BINDING FACTOR BETA source: gene_group n_members: 2 decision: SUBSUMED module: dmel_core_binding_factor inherited_from: CBF - id: FBgg0000769 symbol: CBF name: CORE BINDING FACTOR source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_core_binding_factor - id: FBgg0000770 symbol: MHTF name: MAD HOMOLOGY DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000771 symbol: THAPTF name: THAP DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000772 symbol: ETSTF name: ETS DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000773 symbol: CBFTF name: CCAAT-BINDING FACTOR COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_nf_y_complex - id: FBgg0000774 symbol: DBDTF-U name: UNCLASSIFIED DNA BINDING DOMAIN TRANSCRIPTION FACTORS source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000782 symbol: PSQ name: PIPSQUEAK TRANSCRIPTION FACTORS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: HTH - id: FBgg0000787 symbol: PGANT name: POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALNACT - id: FBgg0000792 symbol: E2FTF name: E2F TRANSCRIPTION FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transcription factor classification by DNA-binding domain. inherited_from: TFS - id: FBgg0000795 symbol: GT name: GLYCOSYLTRANSFERASES source: gene_group n_members: 170 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0000796 symbol: A4GALNACT name: ALPHA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALNACT - id: FBgg0000797 symbol: UGT name: GT1 FAMILY OF UDP-GLYCOSYLTRANSFERASES source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GT - id: FBgg0000800 symbol: ISO name: ISOMERASES source: gene_group n_members: 249 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0000801 symbol: LIG name: LIGASES source: gene_group n_members: 128 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0000802 symbol: RAE name: RACEMASES AND EPIMERASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0000803 symbol: CTI name: CIS-TRANS ISOMERASES source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0000804 symbol: INTO name: INTRAMOLECULAR OXIDOREDUCTASES source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0000805 symbol: INTT name: INTRAMOLECULAR TRANSFERASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0000806 symbol: TOP name: DNA TOPOISOMERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NCISO - id: FBgg0000807 symbol: INTL name: INTRAMOLECULAR LYASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0000808 symbol: LYA name: LYASES source: gene_group n_members: 135 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0000810 symbol: COLIG name: CARBON-OXYGEN LIGASES source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LIG - id: FBgg0000811 symbol: CSLIG name: CARBON-SULFUR LIGASES source: gene_group n_members: 40 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LIG - id: FBgg0000812 symbol: CNLIG name: CARBON-NITROGEN LIGASES source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LIG - id: FBgg0000813 symbol: CCLIG name: CARBON-CARBON LIGASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LIG - id: FBgg0000814 symbol: PELIG name: PHOSPHORIC ESTER LIGASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LIG - id: FBgg0000815 symbol: RAEC name: RACEMASES AND EPIMERASES ACTING ON CARBOHYDRATES AND DERIVATIVES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAE - id: FBgg0000816 symbol: RAE-U name: UNCLASSIFIED RACEMASES AND EPIMERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAE - id: FBgg0000817 symbol: MALI name: MALEYLACETOACETATE ISOMERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CTI - id: FBgg0000818 symbol: PPI name: PEPTIDYL-PROPYL CIS-TRANS ISOMERASES source: gene_group n_members: 33 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CTI - id: FBgg0000819 symbol: INTOAK name: INTRAMOLECULAR OXIDOREDUCTASES INTERCONVERTING ALDOSES AND KETOSES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTO - id: FBgg0000820 symbol: INTOC name: INTRAMOLECULAR OXIDOREDUCTASES TRANSPOSING C-C DOUBLE BONDS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTO - id: FBgg0000821 symbol: PDI name: PROTEIN DISULFIDE ISOMERASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTO - id: FBgg0000822 symbol: PHTR name: INTRAMOLECULAR PHOSPHOTRANSFERASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTT - id: FBgg0000823 symbol: PUS name: PSEUDOURIDINE SYNTHASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTT - id: FBgg0000825 symbol: CHALYA name: CARBON-HALIDE LYASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000826 symbol: CSLYA name: CARBON-SULFUR LYASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000827 symbol: POLYA name: PHOSPHORUS-OXYGEN LYASES source: gene_group n_members: 31 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000829 symbol: COLYA name: CARBON-OXYGEN LYASES source: gene_group n_members: 51 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000830 symbol: CCLYA name: CARBON-CARBON LYASES source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000831 symbol: CNLYA name: CARBON-NITROGEN LYASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0000832 symbol: GH name: GLYCOSIDE HYDROLASES source: gene_group n_members: 98 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0000833 symbol: GH38 name: CLASS II ALPHA-MANNOSIDASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: A-MAN - id: FBgg0000834 symbol: GH47 name: CLASS I ALPHA-MANNOSIDASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: A-MAN - id: FBgg0000835 symbol: ACS name: FATTY ACYL-COA SYNTHETASES source: gene_group n_members: 24 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CSLIG - id: FBgg0000836 symbol: SUCL name: SUCCINYL-COA SYNTHETASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CSLIG - id: FBgg0000838 symbol: AMMLIG name: ACID-AMMONIA LIGASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLIG - id: FBgg0000839 symbol: AALIG name: ACID-AMINO ACID LIGASES source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLIG - id: FBgg0000840 symbol: CLIG name: CYCLO-LIGASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLIG - id: FBgg0000841 symbol: CNLIG-G name: CARBON-NITROGEN LIGASES, WITH GLUTAMINE AS AMIDO-N-DONOR source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLIG - id: FBgg0000843 symbol: OCNLIG name: UNCLASSIFIED CARBON-NITROGEN LIGASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLIG - id: FBgg0000844 symbol: CCB name: COA CARBOXYLASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLIG - id: FBgg0000845 symbol: PCB name: PYRUVATE CARBOXYLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLIG - id: FBgg0000846 symbol: DNALIG name: DNA LIGASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PELIG - id: FBgg0000847 symbol: RNALIG name: RNA LIGASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PELIG - id: FBgg0000848 symbol: RNACYC name: RNA-3'-PHOSPHATE CYCLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PELIG - id: FBgg0000849 symbol: GMANI name: GOLGI CLASS I ALPHA-MANNOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH47 - id: FBgg0000850 symbol: LMAN name: LYSOSOMAL CLASS II ALPHA-MANNOSIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH38 - id: FBgg0000851 symbol: ERMANI name: ENDOPLASMIC RETICULUM CLASS I ALPHA-MANNOSIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH47 - id: FBgg0000852 symbol: GMANII name: GOLGI CLASS II ALPHA-MANNOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH38 - id: FBgg0000853 symbol: EDEM name: ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH47 - id: FBgg0000855 symbol: GH30 name: GLUCOSYLCERAMIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0000856 symbol: GH20 name: BETA-N-ACETYLHEXOSAMINIDASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0000859 symbol: A-MAN name: ALPHA-MANNOSIDASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MAN - id: FBgg0000860 symbol: GH35 name: BETA-GALACTOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0000863 symbol: GH27 name: ALPHA-GALACTOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0000865 symbol: DAPLYA name: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLYA - id: FBgg0000867 symbol: AMIDLYA name: AMIDINE-LYASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLYA - id: FBgg0000868 symbol: DPHLYA name: DNA PHOTOLYASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLYA - id: FBgg0000870 symbol: COLYAP name: CARBON-OXYGEN LYASES, ACTING ON PHOSPHATES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLYA - id: FBgg0000871 symbol: ALDLYA name: ALDEHYDE-LYASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLYA - id: FBgg0000872 symbol: CARBLYA name: CARBOXY-LYASES source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLYA - id: FBgg0000873 symbol: HLYA name: HYDRO-LYASES source: gene_group n_members: 43 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLYA - id: FBgg0000874 symbol: AC name: ADENYLATE CYCLASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: POLYA - id: FBgg0000876 symbol: 5D5PLYA name: 5'-DEOXYRIBOSE-5-PHOSPHATE LYASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLYA - id: FBgg0000877 symbol: PTGS name: PROSTAGLANDIN SYNTHASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: INTO - id: FBgg0000881 symbol: JAKSTAT-C name: JAK-STAT SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 7 decision: SUBSUMED module: dmel_jak_stat_signaling inherited_from: JAKSTAT - id: FBgg0000882 symbol: JAKSTAT-P name: POSITIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY source: signaling_pathway n_members: 16 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000883 symbol: JAKSTAT name: JAK-STAT SIGNALING PATHWAY source: signaling_pathway n_members: 41 decision: NEW_MODULE module: dmel_jak_stat_signaling - id: FBgg0000884 symbol: JAKSTAT-N name: NEGATIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY source: signaling_pathway n_members: 19 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000885 symbol: CA name: CARBONIC ANHYDRASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HLYA - id: FBgg0000886 symbol: FH name: FUMARATE HYDRATASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HLYA - id: FBgg0000887 symbol: HLYA-U name: UNCLASSIFIED HYDRO-LYASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HLYA - id: FBgg0000888 symbol: ACO name: ACONITASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HLYA - id: FBgg0000889 symbol: WNT-TCF name: WNT-TCF SIGNALING PATHWAY source: signaling_pathway n_members: 104 decision: NEW_MODULE module: dmel_wnt_tcf_signaling - id: FBgg0000890 symbol: WNT-TCFC name: WNT-TCF SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 12 decision: SUBSUMED module: dmel_wnt_tcf_signaling inherited_from: WNT-TCF - id: FBgg0000891 symbol: WNT-TCFN name: NEGATIVE REGULATORS OF WNT-TCF SIGNALING PATHWAY source: signaling_pathway n_members: 43 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000892 symbol: WNT-TCFP name: POSITIVE REGULATORS OF WNT-TCF SIGNALING PATHWAY source: signaling_pathway n_members: 52 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000893 symbol: GLYP name: GLYPICANS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000894 symbol: SCF-SLMB name: SCF-SLMB UBIQUITIN LIGASE COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_scf_slimb_ubiquitin_ligase - id: FBgg0000895 symbol: WNT-E name: WNT ENHANCEOSOME source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_wnt_tcf_signaling - id: FBgg0000896 symbol: DES-C name: BETA CATENIN DESTRUCTION COMPLEX APC VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_wnt_tcf_signaling inherited_from: DES - id: FBgg0000898 symbol: INS-P name: POSITIVE REGULATORS OF INSULIN-LIKE RECEPTOR SIGNALING PATHWAY source: signaling_pathway n_members: 22 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000899 symbol: WRD-PP2A name: WRD-PROTEIN PHOSOPHATASE 2A COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_pp2a_holoenzymes inherited_from: PP2A - id: FBgg0000900 symbol: INS-N name: NEGATIVE REGULATORS OF INSULIN-LIKE RECEPTOR SIGNALING PATHWAY source: signaling_pathway n_members: 29 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000901 symbol: TWS-PP2A name: TWS-PROTEIN PHOSOPHATASE 2A COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_pp2a_holoenzymes inherited_from: PP2A - id: FBgg0000902 symbol: HIF name: HYPOXIA-INDUCIBLE FACTOR source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_hif_complex - id: FBgg0000903 symbol: PI3K-IA name: CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_insulin_like_receptor_signaling - id: FBgg0000904 symbol: INS-C name: INSULIN-LIKE RECEPTOR SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 29 decision: SUBSUMED module: dmel_insulin_like_receptor_signaling inherited_from: INS - id: FBgg0000905 symbol: TSC1-2C name: TSC1-TSC2 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_torc1_nutrient_sensing - id: FBgg0000906 symbol: TORC1 name: TORC1 COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_tor_complexes inherited_from: TOR - id: FBgg0000907 symbol: WDB-PP2A name: WDB-PROTEIN PHOSOPHATASE 2A COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_pp2a_holoenzymes inherited_from: PP2A - id: FBgg0000908 symbol: TORC2 name: TORC2 COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_tor_complexes inherited_from: TOR - id: FBgg0000909 symbol: PP2A name: PROTEIN PHOSOPHATASE 2A COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_pp2a_holoenzymes - id: FBgg0000910 symbol: INS name: INSULIN-LIKE RECEPTOR SIGNALING PATHWAY source: signaling_pathway n_members: 78 decision: NEW_MODULE module: dmel_insulin_like_receptor_signaling - id: FBgg0000911 symbol: TOR name: TOR COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_tor_complexes - id: FBgg0000912 symbol: SWH-P name: POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY source: signaling_pathway n_members: 40 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000913 symbol: SWH-C name: HIPPO SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 6 decision: SUBSUMED module: dmel_hippo_signaling inherited_from: SWH - id: FBgg0000914 symbol: KEM name: KIBRA-EX-MER COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_hippo_signaling - id: FBgg0000915 symbol: STRIPAK name: STRIATIN-INTERACTING PHOSPHATASE AND KINASE COMPLEX source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_stripak_complex - id: FBgg0000916 symbol: SWH-N name: NEGATIVE REGULATORS OF HIPPO SIGNALING PATHWAY source: signaling_pathway n_members: 49 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000917 symbol: SWH name: HIPPO SIGNALING PATHWAY source: signaling_pathway n_members: 92 decision: NEW_MODULE module: dmel_hippo_signaling - id: FBgg0000918 symbol: WNT-PRO name: WNT PRODUCTION source: signaling_pathway n_members: 2 decision: SUBSUMED module: dmel_wnt_tcf_signaling inherited_from: WNT-TCF - id: FBgg0000920 symbol: AKR name: ALCOHOL DEHYDROGENASES (NADP-DEPENDENT) source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0000921 symbol: MDH name: MALATE DEHYDROGENASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0000922 symbol: OXRCHOH name: CH-OH GROUP OXIDOREDUCTASES source: gene_group n_members: 128 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000923 symbol: OXR name: OXIDOREDUCTASES source: gene_group n_members: 557 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0000924 symbol: OXRNAD name: CH-OH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 107 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHOH - id: FBgg0000925 symbol: SD name: CH-OH STEROID DEHYDROGENASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0000926 symbol: ADH name: UNCLASSIFIED ALCOHOL DEHYDROGENASES (NAD-DEPENDENT) source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ADHNAD - id: FBgg0000927 symbol: OXRNAD-U name: UNCLASSIFIED CH-OH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 30 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0000928 symbol: GMCOR name: GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHOH - id: FBgg0000933 symbol: OXR-U name: UNCLASSIFIED OXIDOREDUCTASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000934 symbol: TORS name: TORSO SIGNALING PATHWAY source: signaling_pathway n_members: 31 decision: NEW_MODULE module: dmel_torso_signaling - id: FBgg0000935 symbol: SEVL-C name: SEVENLESS SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 17 decision: SUBSUMED module: dmel_sevenless_signaling inherited_from: SEVL - id: FBgg0000936 symbol: TORS-P name: POSITIVE REGULATORS OF TORSO SIGNALING PATHWAY source: signaling_pathway n_members: 2 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000937 symbol: TORS-C name: TORSO SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 22 decision: SUBSUMED module: dmel_torso_signaling inherited_from: TORS - id: FBgg0000938 symbol: SEVL-P name: POSITIVE REGULATORS OF SEVENLESS SIGNALING PATHWAY source: signaling_pathway n_members: 8 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000940 symbol: TORS-N name: NEGATIVE REGULATORS OF TORSO SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000941 symbol: SEVL name: SEVENLESS SIGNALING PATHWAY source: signaling_pathway n_members: 30 decision: NEW_MODULE module: dmel_sevenless_signaling - id: FBgg0000942 symbol: SEVL-N name: NEGATIVE REGULATORS OF SEVENLESS SIGNALING PATHWAY source: signaling_pathway n_members: 5 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000944 symbol: OXRCHOH-U name: UNCLASSIFIED CH-OH OXIDOREDUCTASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHOH - id: FBgg0000945 symbol: GPDH name: GLYCEROL-3-PHOSPHATE DEHYDROGENASES (QUINONE) source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHOH - id: FBgg0000946 symbol: CYP name: CYCLOPHILINS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPI - id: FBgg0000947 symbol: FKBP name: FK506-BINDING PROTEINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPI - id: FBgg0000948 symbol: PARV name: PARVULINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPI - id: FBgg0000949 symbol: PTPA name: PROTEIN PHOSPHATASE 2 PHOSPHATASE ACTIVATORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPI - id: FBgg0000950 symbol: EGFR-N name: NEGATIVE REGULATORS OF EGFR SIGNALING PATHWAY source: signaling_pathway n_members: 38 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000951 symbol: EGFR-C name: EGFR SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 25 decision: SUBSUMED module: dmel_egfr_signaling inherited_from: EGFR-RTK - id: FBgg0000953 symbol: EGF-PRO name: EGFR LIGAND PRODUCTION source: signaling_pathway n_members: 6 decision: SUBSUMED module: dmel_egfr_signaling inherited_from: EGFR-RTK - id: FBgg0000954 symbol: IRHOM name: RHOMBOID PSEUDOPROTEASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: RHOM-L - id: FBgg0000955 symbol: RHOM-L name: RHOMBOID-LIKE PROTEINS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000956 symbol: EGFR-P name: POSITIVE REGULATORS OF EGFR SIGNALING PATHWAY source: signaling_pathway n_members: 17 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000957 symbol: RHOM name: RHOMBOID PROTEASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: RHOM-L - id: FBgg0000958 symbol: EGFR-RTK name: EGFR SIGNALING PATHWAY source: signaling_pathway n_members: 83 decision: NEW_MODULE module: dmel_egfr_signaling - id: FBgg0000959 symbol: EGFR-AG name: EGFR AGONISTS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000960 symbol: ALP name: ALKALINE PHOSPHATASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000961 symbol: ACP name: ACID PHOSPHATASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0000962 symbol: ACBP name: ACYL-COA BINDING DOMAIN-CONTAINING PROTEINS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000963 symbol: M13 name: M13 METALLOENDOPEPTIDASES source: gene_group n_members: 28 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0000964 symbol: NEPL name: NEPRILYSIN-LIKE METALLOENDOPEPTIDASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: M13 - id: FBgg0000965 symbol: ELOVL name: FATTY ACID ELONGASES source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0000966 symbol: FGF name: FIBROBLAST GROWTH FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0000967 symbol: FGFR name: FGFR SIGNALING PATHWAY source: signaling_pathway n_members: 35 decision: NEW_MODULE module: dmel_fgfr_signaling - id: FBgg0000968 symbol: FGFR-C name: FGFR SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 22 decision: SUBSUMED module: dmel_fgfr_signaling inherited_from: FGFR - id: FBgg0000969 symbol: FGFR-N name: NEGATIVE REGULATORS OF FGFR SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000970 symbol: FGFR-P name: POSITIVE REGULATORS OF FGFR SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000972 symbol: PVR-RTK name: PVR SIGNALING PATHWAY source: signaling_pathway n_members: 41 decision: NEW_MODULE module: dmel_pvr_signaling - id: FBgg0000973 symbol: PVR-C name: PVR SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 33 decision: SUBSUMED module: dmel_pvr_signaling inherited_from: PVR-RTK - id: FBgg0000974 symbol: PVR-N name: NEGATIVE REGULATORS OF PVR SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000975 symbol: PVR-P name: POSITIVE REGULATORS OF PVR SIGNALING PATHWAY source: signaling_pathway n_members: 1 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000977 symbol: AARSL name: AMINOACYL-TRNA SYNTHETASE-LIKE source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: COLIG - id: FBgg0000978 symbol: HH-SMO name: HEDGEHOG SIGNALING PATHWAY source: signaling_pathway n_members: 98 decision: NEW_MODULE module: dmel_hedgehog_signaling - id: FBgg0000979 symbol: HH-SMOC name: HEDGEHOG SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 7 decision: SUBSUMED module: dmel_hedgehog_signaling inherited_from: HH-SMO - id: FBgg0000980 symbol: HH-SMON name: NEGATIVE REGULATORS OF HEDGEHOG SIGNALING PATHWAY source: signaling_pathway n_members: 58 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000981 symbol: HH-SMOP name: POSITIVE REGULATORS OF HEDGEHOG SIGNALING PATHWAY source: signaling_pathway n_members: 43 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0000984 symbol: OXRAOD name: ALDEHYDE OR OXO OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAO - id: FBgg0000985 symbol: OXRAONAD name: ALDEHYDE OR OXO OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 31 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAO - id: FBgg0000986 symbol: OXRAOO name: ALDEHYDE OR OXO OXIDOREDUCTASES, WITH OXYGEN AS ACCEPTOR source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAO - id: FBgg0000987 symbol: OXRAO name: ALDEHYDE OR OXO GROUP OXIDOREDUCTASES source: gene_group n_members: 43 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000989 symbol: OXRCHCHO name: CH-CH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCH - id: FBgg0000990 symbol: ACAD name: ACYL-COA DEHYDROGENASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCH - id: FBgg0000991 symbol: ACAO name: ACYL-COA OXIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCHO - id: FBgg0000992 symbol: OXRCHCH name: CH-CH GROUP OXIDOREDUCTASES source: gene_group n_members: 34 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000993 symbol: OXRCHCHNAD name: CH-CH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCH - id: FBgg0000994 symbol: OXRCHNH2D name: CH-NH2 OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH2 - id: FBgg0000995 symbol: OXRCHNH2NAD name: CH-NH2 OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH2 - id: FBgg0000996 symbol: OXRCHNH2 name: CH-NH2 GROUP OXIDOREDUCTASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000997 symbol: OXRCHNH2O name: CH-NH2 OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH2 - id: FBgg0000998 symbol: OXRCHNH name: CH-NH GROUP OXIDOREDUCTASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0000999 symbol: OXRCHNHNAD name: CH-NH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH - id: FBgg0001000 symbol: OXRCHNH-U name: UNCLASSIFIED CH-NH OXIDOREDUCTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH - id: FBgg0001001 symbol: OXRNADHO name: NAD(P)H OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNADH - id: FBgg0001003 symbol: OXRNADH name: NAD(P)H OXIDOREDUCTASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001004 symbol: OXRNADH-U name: UNCLASSIFIED NAD(P)H OXIDOREDUCTASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNADH - id: FBgg0001005 symbol: OXRNADHH name: NAD(P)H OXIDOREDUCTASES, HEME PROTEIN AS ACCEPTOR source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNADH - id: FBgg0001007 symbol: OXRSO name: SULFUR OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001009 symbol: OXRS name: SULFUR GROUP OXIDOREDUCTASES source: gene_group n_members: 48 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001010 symbol: OXRSD name: SULFUR OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001011 symbol: OXRSNAD name: SULFUR OXIDOREDUCTASES, NAD(P) AS ACCEPTOR source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001012 symbol: OXRN name: OTHER NITROGENOUS GROUP OXIDOREDUCTASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001013 symbol: OXRDP name: DIPHENOL OXIDOREDUCTASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001015 symbol: MCIV-C name: MITOCHONDRIAL COMPLEX IV - CORE SUBUNITS source: gene_group n_members: 3 decision: SUBSUMED module: mitochondrial_complex_iv inherited_from: MCIV - id: FBgg0001016 symbol: OXRDPO name: DIPHENOL OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRDP - id: FBgg0001017 symbol: MCIII-C name: MITOCHONDRIAL COMPLEX III - CORE SUBUNITS source: gene_group n_members: 4 decision: SUBSUMED module: mitochondrial_complex_iii inherited_from: MCIII - id: FBgg0001018 symbol: HH-PRO name: HEDGEHOG PRODUCTION source: signaling_pathway n_members: 2 decision: SUBSUMED module: dmel_hedgehog_signaling inherited_from: HH-SMO - id: FBgg0001019 symbol: DUS name: TRNA DIHYDROURIDINE SYNTHASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCHNAD - id: FBgg0001024 symbol: DIOX-U name: UNCLASSIFIED DIOXYGENASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DIOX - id: FBgg0001028 symbol: SOD name: SUPEROXIDE DISMUTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001029 symbol: OXRMI name: METAL ION OXIDOREDUCTASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001030 symbol: FOXS name: FERROXIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRMI - id: FBgg0001032 symbol: OXRMINAD name: METAL ION OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRMI - id: FBgg0001033 symbol: OXRCHCH2 name: CH OR CH2 GROUP OXIDOREDUCTASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001034 symbol: GPX name: GLUTATHIONE PEROXIDASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PX - id: FBgg0001036 symbol: CATA name: CATALASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PX - id: FBgg0001037 symbol: PRXN name: PEROXIREDOXINS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PX - id: FBgg0001038 symbol: PX-U name: UNCLASSIFIED PEROXIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PX - id: FBgg0001039 symbol: OXRPX name: PEROXIDE OXIDOREDUCTASES source: gene_group n_members: 42 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001040 symbol: PX name: PEROXIDASES source: gene_group n_members: 42 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRPX - id: FBgg0001041 symbol: OXRPMO2O-U name: UNCLASSIFIED 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRPMO2O - id: FBgg0001042 symbol: PPDOX name: PEPTIDYL-PROLINE DIOXYGENASES source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRPMO2O - id: FBgg0001043 symbol: MOOX-U name: UNCLASSIFIED MONOOXYGENASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MOOX - id: FBgg0001044 symbol: OXRPMOA name: MONOOXYGENASES, REDUCED ASCORBATE AS ONE DONOR source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MOOX - id: FBgg0001045 symbol: OXRPMON name: MONOOXYGENASES, NAD(P)H AS ONE DONOR source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MOOX - id: FBgg0001048 symbol: OXRPMO2O name: 2-OXOGLUTARATE-DEPENDENT DIOXYGENASES source: gene_group n_members: 54 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DIOX - id: FBgg0001050 symbol: OXRPMOP name: MONOOXYGENASES, REDUCED PTERIDINE AS ONE DONOR source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MOOX - id: FBgg0001051 symbol: TLR name: TOLL RECEPTORS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001052 symbol: SPZ name: SPATZLES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001053 symbol: TL-NFN name: NEGATIVE REGULATORS OF TOLL-NF-kappaB SIGNALING PATHWAY source: signaling_pathway n_members: 19 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001054 symbol: DORS name: DORSAL GROUP source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_toll_signaling - id: FBgg0001055 symbol: TL-SPZN name: NEGATIVE REGULATORS OF SPATZLE ACTIVATING PATHWAY source: signaling_pathway n_members: 4 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001056 symbol: TL-SPZC name: EXTRACELLULAR SPATZLE ACTIVATING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 23 decision: SUBSUMED module: dmel_toll_signaling inherited_from: TL-CAN - id: FBgg0001057 symbol: TL-NFP name: POSITIVE REGULATORS OF TOLL-NF-kappaB SIGNALING PATHWAY source: signaling_pathway n_members: 23 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001058 symbol: TL-NFC name: TOLL-NF-kappaB SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 12 decision: SUBSUMED module: dmel_toll_signaling inherited_from: TL-CAN - id: FBgg0001059 symbol: TL-CAN name: TOLL SIGNALING PATHWAY source: signaling_pathway n_members: 80 decision: NEW_MODULE module: dmel_toll_signaling - id: FBgg0001060 symbol: AGPAT name: 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LPLAT - id: FBgg0001061 symbol: GPAT name: GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001062 symbol: GSC name: GAMMA SECRETASE COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_gamma_secretase_complex - id: FBgg0001063 symbol: NTCH-N name: NEGATIVE REGULATORS OF NOTCH SIGNALING PATHWAY source: signaling_pathway n_members: 37 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001064 symbol: NTCH-C name: NOTCH SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 12 decision: SUBSUMED module: dmel_notch_signaling inherited_from: NTCH - id: FBgg0001065 symbol: BRD-F name: BEARDED GENE FAMILY source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001066 symbol: CNM name: CSL-NOTCH-MASTERMIND TRANSCRIPTION FACTOR COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_notch_signaling - id: FBgg0001067 symbol: DSL name: NOTCH LIGANDS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001068 symbol: NTCH name: NOTCH SIGNALING PATHWAY source: signaling_pathway n_members: 91 decision: NEW_MODULE module: dmel_notch_signaling - id: FBgg0001069 symbol: NTCH-P name: POSITIVE REGULATORS OF NOTCH SIGNALING PATHWAY source: signaling_pathway n_members: 48 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001070 symbol: I2DH name: L-IDITOL 2-DEHYDROGENASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ADHNAD - id: FBgg0001071 symbol: RDH name: ALL-TRANS-RETINOL DEHYDROGENASES (NAD-DEPENDENT) source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ADHNAD - id: FBgg0001072 symbol: GPDHN name: GLYCEROL-3-PHOSPHATE DEHYDROGENASES (NAD+) source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0001073 symbol: IDH name: ISOCITRATE DEHYDROGENASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0001075 symbol: S1A name: PEPTIDASE FAMILY S1A source: gene_group n_members: 258 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1 - id: FBgg0001076 symbol: S1AP name: S1A SERINE PROTEASES source: gene_group n_members: 190 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1A - id: FBgg0001077 symbol: S1A-NPH name: S1A NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 68 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1A - id: FBgg0001078 symbol: SP-T name: S1A SERINE PROTEASES - TRYPSIN-LIKE source: gene_group n_members: 114 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1AP - id: FBgg0001079 symbol: SP-C name: S1A SERINE PROTEASES - CHYMOTRYPSIN-LIKE source: gene_group n_members: 61 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1AP - id: FBgg0001080 symbol: SP-E name: S1A SERINE PROTEASES - ELASTASE-LIKE source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1AP - id: FBgg0001081 symbol: S1 name: PEPTIDASE FAMILY S1 source: gene_group n_members: 260 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001082 symbol: S1CP name: S1C SERINE PEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: S1 - id: FBgg0001084 symbol: BMP-N name: NEGATIVE REGULATORS OF BMP SIGNALING PATHWAY source: signaling_pathway n_members: 41 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001085 symbol: BMP-C name: BMP SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 11 decision: SUBSUMED module: dmel_bmp_signaling inherited_from: BMP-MAD - id: FBgg0001086 symbol: BMP-MAD name: BMP SIGNALING PATHWAY source: signaling_pathway n_members: 69 decision: NEW_MODULE module: dmel_bmp_signaling - id: FBgg0001087 symbol: TGF-R name: TGF-BETA RECEPTOR FAMILY source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TKL - id: FBgg0001088 symbol: BMP-TGF name: BONE MORPHOGENETIC PROTEINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TGF - id: FBgg0001089 symbol: TGF-RII name: TGF-BETA TYPE II RECEPTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TGF-R - id: FBgg0001090 symbol: TKL-NR name: NON-RECEPTOR TKL KINASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TKL - id: FBgg0001091 symbol: ACT-N name: NEGATIVE REGULATORS OF ACTIVIN SIGNALING PATHWAY source: signaling_pathway n_members: 2 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001092 symbol: ACT-C name: ACTIVIN SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 8 decision: SUBSUMED module: dmel_activin_signaling inherited_from: ACT-SMAD2 - id: FBgg0001093 symbol: ACT-SMAD2 name: ACTIVIN SIGNALING PATHWAY source: signaling_pathway n_members: 13 decision: NEW_MODULE module: dmel_activin_signaling - id: FBgg0001094 symbol: BMP-P name: POSITIVE REGULATORS OF BMP SIGNALING PATHWAY source: signaling_pathway n_members: 22 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001095 symbol: ACT-P name: POSITIVE REGULATORS OF ACTIVIN SIGNALING PATHWAY source: signaling_pathway n_members: 4 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001096 symbol: TGF-RI name: TGF-BETA TYPE I RECEPTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TGF-R - id: FBgg0001097 symbol: ACT-TGF name: ACTIVINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TGF - id: FBgg0001098 symbol: TGF name: TRANSFORMING GROWTH FACTOR-BETA FAMILY source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001099 symbol: ATT name: ATTACINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0001100 symbol: CEC name: CECROPINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0001101 symbol: AMP name: ANTIMICROBIAL PEPTIDES source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0001103 symbol: CDA name: CHITIN DEACETYLASE-LIKE FAMILY source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001105 symbol: RLIG name: RECEPTOR LIGANDS source: gene_group n_members: 117 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. - id: FBgg0001106 symbol: TM-R name: TRANSMEMBRANE RECEPTORS source: gene_group n_members: 506 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. - id: FBgg0001107 symbol: PVF name: PDGF- AND VEGF-RELATED FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001108 symbol: RLIG-U name: UNCLASSIFIED RECEPTOR LIGANDS source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001109 symbol: TMR-U name: UNCLASSIFIED TRANSMEMBRANE RECEPTORS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001110 symbol: PENT name: PENTOSYLTRANSFERASES source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GT - id: FBgg0001113 symbol: GLCT name: GLUCOSYLTRANSFERASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001114 symbol: TTAK name: ALDEHYDE OR KETONIC GROUP TRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001115 symbol: TTSEC name: SELENIUM-CONTAINING GROUP TRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001116 symbol: MOEA name: MOLYBDOPTERIN MOLYBDENUMTRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001118 symbol: PTF name: PRENYLTRANSFERASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAT - id: FBgg0001120 symbol: AAT-U name: UNCLASSIFIED ALKYL OR ARYL (OTHER THAN METHYL) TRANSFERASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAT - id: FBgg0001121 symbol: AAT name: ALKYL OR ARYL (NON-METHYL) TRANSFERASES source: gene_group n_members: 66 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001123 symbol: TA name: TRANSAMINASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTN - id: FBgg0001124 symbol: TFTN name: NITROGENOUS GROUP TRANSFERASES source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001126 symbol: PCSN name: PEPTIDYL-CYSTEINE S-NITROSYLASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTN - id: FBgg0001128 symbol: SUTS name: SULFURTRANSFERASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TTSG - id: FBgg0001129 symbol: TTSG name: SULFUR-CONTAINING GROUP TRANSFERASES source: gene_group n_members: 31 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001130 symbol: HSSF name: HEPARAN SULFATE SULFOTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STS - id: FBgg0001131 symbol: NAG6SF name: N-ACETYLGLUCOSAMINE-6-O-SULFOTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STS - id: FBgg0001132 symbol: STS name: SULFOTRANSFERASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TTSG - id: FBgg0001133 symbol: STS-U name: UNCLASSIFIED SULFOTRANSFERASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: STS - id: FBgg0001134 symbol: ART name: ADP-RIBOSYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001135 symbol: PENT-U name: UNCLASSIFIED PENTOSYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001139 symbol: APRT name: AMIDOPHOSPHORIBOSYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001140 symbol: UPP name: URIDINE PHOSPHORYLASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001141 symbol: PNP name: PURINE NUCLEOSIDE PHOSPHORYLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001142 symbol: KIN name: KINASES source: gene_group n_members: 361 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCGTF - id: FBgg0001143 symbol: OBST name: OBSTRUCTOR FAMILY source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001144 symbol: TFTC name: ONE-CARBON GROUP TRANSFERASES source: gene_group n_members: 132 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001146 symbol: TRNAMT name: TRNA METHYLTRANSFERASES source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAMT - id: FBgg0001147 symbol: METH-U name: UNCLASSIFIED METHYLTRANSFERASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: METH - id: FBgg0001148 symbol: PMETH-U name: UNCLASSIFIED PROTEIN METHYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-METH - id: FBgg0001149 symbol: RRNAMT name: RRNA METHYLTRANSFERASES source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAMT - id: FBgg0001153 symbol: HMFRT name: HYDROXYMETHYL-, FORMYL- AND RELATED TRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTC - id: FBgg0001156 symbol: RNAMT name: RNA METHYLTRANSFERASES source: gene_group n_members: 51 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: METH - id: FBgg0001157 symbol: MRNAMT name: MRNA METHYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAMT - id: FBgg0001159 symbol: METH name: METHYLTRANSFERASES source: gene_group n_members: 126 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTC - id: FBgg0001162 symbol: NAAAT name: NON-AMINOACYL ACYLTRANSFERASES source: gene_group n_members: 175 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AT - id: FBgg0001163 symbol: HAT name: HISTONE ACETYLTRANSFERASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KAT - id: FBgg0001167 symbol: FAS name: FATTY ACID SYNTHASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001168 symbol: AT name: ACYLTRANSFERASES source: gene_group n_members: 386 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001169 symbol: ACTT name: ACETYLTRANSFERASES source: gene_group n_members: 55 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001171 symbol: SUMOT name: SUMO TRANSFERASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001172 symbol: ULT name: UBIQUITIN-LIKE PROTEIN TRANSFERASES source: gene_group n_members: 201 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAGT - id: FBgg0001173 symbol: UFM1T name: UFM1 TRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001174 symbol: CPF name: CPF CUTICLE PROTEIN FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001175 symbol: CPLCA name: CPLCA CUTICLE PROTEIN FAMILY source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001176 symbol: CPR name: CPR CUTICLE PROTEIN FAMILY source: gene_group n_members: 103 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001177 symbol: CLECT name: C-TYPE LECTIN-LIKE source: gene_group n_members: 40 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001178 symbol: CP name: CUTICLE PROTEIN FAMILIES source: gene_group n_members: 160 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001179 symbol: TWDL name: TWEEDLE CUTICLE PROTEIN FAMILY source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001180 symbol: MUCS name: MUCINS source: gene_group n_members: 24 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001181 symbol: SPON name: SPONDINS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001182 symbol: CP-U name: UNCLASSIFIED CUTICLE PROTEINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001183 symbol: CPLCP name: CPLCP CUTICLE PROTEIN FAMILY source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001184 symbol: VMP name: VITELLINE MEMBRANE PROTEINS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_eggshell_structural_proteins - id: FBgg0001185 symbol: COL name: COLLAGENS source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_basement_membrane_network - id: FBgg0001186 symbol: CBD name: CHITIN BINDING DOMAIN-CONTAINING PROTEINS source: gene_group n_members: 106 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001187 symbol: CPLCG name: CPLCG CUTICLE PROTEIN FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CP - id: FBgg0001188 symbol: CHORN name: CHORION PROTEINS source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_eggshell_structural_proteins - id: FBgg0001189 symbol: GLUE name: GLUE PROTEINS source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_salivary_glue_secretion - id: FBgg0001190 symbol: LMN name: LAMININS source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_basement_membrane_network - id: FBgg0001191 symbol: GBP name: GROWTH-BLOCKING PEPTIDES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: RLIG - id: FBgg0001192 symbol: E3-RING name: RING DOMAIN E3 UBIQUITIN LIGASES source: gene_group n_members: 120 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3 - id: FBgg0001193 symbol: IKB name: NUCLEAR FACTOR - KAPPA B INHIBITOR FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001194 symbol: IMD name: IMD SIGNALING PATHWAY source: signaling_pathway n_members: 82 decision: NEW_MODULE module: dmel_imd_signaling - id: FBgg0001195 symbol: IMD-C name: IMD SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 19 decision: SUBSUMED module: dmel_imd_signaling inherited_from: IMD - id: FBgg0001196 symbol: IMD-N name: NEGATIVE REGULATORS OF IMD SIGNALING PATHWAY source: signaling_pathway n_members: 45 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001197 symbol: IMD-P name: POSITIVE REGULATORS OF IMD SIGNALING PATHWAY source: signaling_pathway n_members: 19 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001198 symbol: DCMT name: ASPARTATE CARBAMOYLTRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTC - id: FBgg0001199 symbol: RNAMT-U name: UNCLASSIFIED RNA METHYLTRANSFERASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAMT - id: FBgg0001200 symbol: DNAPOL name: DNA POLYMERASE COMPLEXES source: gene_group n_members: 15 decision: NEW_MODULE module: dmel_dna_polymerase_complexes - id: FBgg0001202 symbol: AAKGT name: ACYL TO ALKYL ACYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AT - id: FBgg0001203 symbol: AT-U name: UNCLASSIFIED ACYLTRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AT - id: FBgg0001205 symbol: PCSPT name: PALMITOYLTRANSFERASES source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001207 symbol: NAAAT-U name: UNCLASSIFIED NON-AMINOACYL ACYLTRANSFERASES source: gene_group n_members: 40 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001208 symbol: AAGT name: AMINOACYLTRANSFERASES source: gene_group n_members: 207 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AT - id: FBgg0001209 symbol: DNAPOLA name: DNA POLYMERASE ALPHA-PRIMASE COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_dna_polymerase_complexes inherited_from: DNAPOL - id: FBgg0001210 symbol: DNAPOLE name: DNA POLYMERASE EPSILON COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_dna_polymerase_complexes inherited_from: DNAPOL - id: FBgg0001211 symbol: DNAPOLD name: DNA POLYMERASE DELTA COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_dna_polymerase_complexes inherited_from: DNAPOL - id: FBgg0001212 symbol: DNAPOLZ name: DNA POLYMERASE ZETA source: gene_group n_members: 4 decision: SUBSUMED module: dmel_dna_polymerase_complexes inherited_from: DNAPOL - id: FBgg0001216 symbol: DNAPOLG name: DNA POLYMERASE GAMMA COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_dna_polymerase_complexes inherited_from: DNAPOL - id: FBgg0001218 symbol: UBT name: UBIQUITIN TRANSFERASES source: gene_group n_members: 181 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001219 symbol: NEDD8T name: NEDD8 TRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001220 symbol: ATG12T name: ATG12 TRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001221 symbol: ATG8T name: ATG8 TRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULT - id: FBgg0001222 symbol: CYP450 name: CYTOCHROME P450 source: gene_group n_members: 87 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MOOX - id: FBgg0001223 symbol: E3-KCMF1 name: KCMF1 UBIQUITIN LIGASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3 - id: FBgg0001224 symbol: E3-U name: UNCLASSIFIED E3 UBIQUITIN LIGASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E3 - id: FBgg0001225 symbol: OXRCHCHO-U name: UNCLASSIFIED CH-CH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCHO - id: FBgg0001226 symbol: TRFS name: TRANSFERASES source: gene_group n_members: 1252 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0001227 symbol: UBAE name: UBIQUITIN ACTIVATING ENZYMES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001228 symbol: SUMOAE name: SUMO ACTIVATING ENZYMES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001229 symbol: NEDD8AE name: NEDD8 ACTIVATING ENZYMES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001230 symbol: ATGAE name: ATG8/12 ACTIVATING ENZYMES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001231 symbol: UFM1AE name: UFM1 ACTIVATING ENZYMES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001232 symbol: URM1AE name: URM1 ACTIVATING ENZYMES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: E1 - id: FBgg0001233 symbol: GST-MC name: MICROSOMAL GLUTATHIONE S-TRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GST - id: FBgg0001234 symbol: TRAPPII name: TRAPPII COMPLEX source: gene_group n_members: 9 decision: SUBSUMED module: dmel_trapp_complexes inherited_from: TRAPP - id: FBgg0001235 symbol: TRAPPIII name: TRAPPIII COMPLEX source: gene_group n_members: 11 decision: SUBSUMED module: dmel_trapp_complexes inherited_from: TRAPP - id: FBgg0001236 symbol: CO-METH name: PROTEIN CARBOXYL O-METHYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-METH - id: FBgg0001237 symbol: GN-METH name: PROTEIN-GLUTAMINE N-METHYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-METH - id: FBgg0001238 symbol: TN-ACT name: TUBULIN N-ACETYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KAT - id: FBgg0001240 symbol: LPLAT name: LYSOPHOSPHOLIPID ACYLTRANSFERASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001241 symbol: LPLAT-U name: UNCLASSIFIED LYSOPHOSPHOLIPID ACYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LPLAT - id: FBgg0001242 symbol: SUCT name: SUCCINYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001243 symbol: NUTF name: NUCLEOTIDYLTRANSFERASES source: gene_group n_members: 65 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCGTF - id: FBgg0001244 symbol: ADTF name: ADENYLYLTRANSFERASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001245 symbol: CYTF name: CYTIDYLYLTRANSFERASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001247 symbol: DNAPOL-C name: DNA POLYMERASE CATALYTIC SUBUNITS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001248 symbol: GUTF name: GUANYLYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001250 symbol: RNAPOL-C name: RNA POLYMERASE CATALYTIC SUBUNITS source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001251 symbol: URTF name: URIDYLYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001257 symbol: NUTF-U name: UNCLASSIFIED NUCLEOTIDYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001258 symbol: DPTF name: DIPHOSPHOSPHOTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCGTF - id: FBgg0001259 symbol: NUK name: NUCLEOSIDE KINASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUBCK - id: FBgg0001260 symbol: CHK name: CARBOHYDRATE KINASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0001261 symbol: PCGTF-U name: UNCLASSIFIED PHOSPHORUS-CONTAINING GROUP TRANSFERASES source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCGTF - id: FBgg0001264 symbol: PSPYK name: PSEUDO-PYRUVATE KINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0001265 symbol: KIN-U name: UNCLASSIFIED KINASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0001268 symbol: PCGTF name: PHOSPHORUS-CONTAINING GROUP TRANSFERASES source: gene_group n_members: 448 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001270 symbol: NTK name: NUCLEOSIDE MONOPHOSPHATE KINASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUBCK - id: FBgg0001271 symbol: NUDK name: NUCLEOSIDE DIPHOSPHATE KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUBCK - id: FBgg0001272 symbol: SR name: SERINE AND ARGININE RICH SPLICING FACTORS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001273 symbol: SR-C name: CANONICAL SERINE AND ARGININE RICH SPLICING FACTORS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: SR - id: FBgg0001274 symbol: SR-NC name: NON-CANONICAL SERINE AND ARGININE RICH SPLICING FACTORS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: SR - id: FBgg0001275 symbol: CKS name: ARGININE KINASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0001276 symbol: PI-3K name: PHOSPHATIDYLINOSITOL 3 KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PI-K - id: FBgg0001277 symbol: PI-4K name: PHOSPHATIDYLINOSITOL 4 KINASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PI-K - id: FBgg0001278 symbol: PI-5K name: PHOSPHATIDYLINOSITOL 5 KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PI-K - id: FBgg0001280 symbol: AMMOLYA name: AMMONIA-LYASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNLYA - id: FBgg0001281 symbol: SRP name: SIGNAL RECOGNITION PARTICLE source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_srp_cotranslational_targeting - id: FBgg0001282 symbol: SRPR name: SIGNAL RECOGNITION PARTICLE RECEPTOR source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_srp_cotranslational_targeting - id: FBgg0001283 symbol: SEC61T-CG8860 name: SEC61 TRANSLOCON - CG8860 VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_sec61_translocon inherited_from: SEC61TC - id: FBgg0001284 symbol: PAPS name: POLY(A) POLYMERASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ADTF - id: FBgg0001285 symbol: ADTF-U name: UNCLASSIFIED ADENYLYLTRANSFERASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ADTF - id: FBgg0001286 symbol: ICNG name: CYCLIC NUCLEOTIDE-ACTIVATED CATION CHANNELS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGIC - id: FBgg0001287 symbol: CNG name: CYCLIC NUCLEOTIDE-GATED CHANNEL SUBUNITS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001288 symbol: HEXT name: HEXOSYLTRANSFERASES source: gene_group n_members: 114 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GT - id: FBgg0001289 symbol: EMC name: ER MEMBRANE PROTEIN COMPLEX EMC2A VARIANT source: gene_group n_members: 9 decision: SUBSUMED module: dmel_er_membrane_protein_complex inherited_from: EMPC - id: FBgg0001290 symbol: KMT-U name: UNCLASSIFIED PROTEIN-LYSINE N-METHYLTRANSFERASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KMT - id: FBgg0001291 symbol: GALNACT name: N-ACETYLGALACTOSAMINYLTRANSFERASES source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001292 symbol: GLCNACT name: N-ACETYLGLUCOSAMINYLTRANSFERASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001293 symbol: FUCT name: FUCOSYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001294 symbol: GALT name: GALACTOSYLTRANSFERASES source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001295 symbol: GLCAT name: GLUCURONOSYLTRANSFERASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001296 symbol: MANT name: MANNOSYLTRANSFERASES source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001297 symbol: OLIT name: OLIGOSACCHARYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001298 symbol: HEXT-U name: UNCLASSIFIED HEXOSYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEXT - id: FBgg0001299 symbol: XYLT name: XYLOSYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PENT - id: FBgg0001300 symbol: SIAT name: SIALYLTRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GT - id: FBgg0001301 symbol: FAAH name: FATTY ACID AMIDE HYDROLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001302 symbol: HYD name: HYDROLASES source: gene_group n_members: 1409 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0001303 symbol: AMC name: AMINOACYLASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001304 symbol: CNHNP name: CARBON-NITROGEN HYDROLASES (NON-PEPTIDASE) source: gene_group n_members: 85 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001305 symbol: NAMAA name: N-ACETYLMURAMOYL-L-ALANINE AMIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001307 symbol: APAS name: ASPARAGINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001308 symbol: CNHLA name: CARBON-NITROGEN HYDROLASES OF LINEAR AMIDES source: gene_group n_members: 57 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHNP - id: FBgg0001309 symbol: B4GALNACT name: BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALNACT - id: FBgg0001310 symbol: CS name: CHONDROITIN SYNTHASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALNACT - id: FBgg0001311 symbol: B3GLCNACT name: BETA 1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0001313 symbol: POGLCNACT name: PROTEIN O-GLCNAC TRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0001314 symbol: CHS name: CHITIN SYNTHASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0001315 symbol: MGAT name: MANNOSYL-GLYCOPROTEIN N-ACETYLGLUCOSAMINYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0001316 symbol: PGGLCNACT name: PROTEOGLYCAN N-ACETYLGLUCOSAMINYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0001320 symbol: C1GALT name: CORE 1 BETA 1,3-GALACTOSYLTRANSFERASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALT - id: FBgg0001321 symbol: B3GALT name: BETA-N-ACETYLGLUCOSAMINE BETA-1,3-GALACTOSYLTRANSFERASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALT - id: FBgg0001322 symbol: PCGALT name: PROCOLLAGEN GALACTOSYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALT - id: FBgg0001323 symbol: GALT-U name: UNCLASSIFIED GALACTOSYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALT - id: FBgg0001324 symbol: PPDGLCT name: DOLICHYL PYROPHOSPHATE GLUCOSYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCT - id: FBgg0001325 symbol: GLCT-U name: UNCLASSIFIED GLUCOSYLTRANSFERASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCT - id: FBgg0001326 symbol: PPDMANT name: DOLICHYL PYROPHOSPHATE MANNOSYLTRANSFERASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MANT - id: FBgg0001327 symbol: GPIMANT name: GPI MANNOSYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MANT - id: FBgg0001328 symbol: POMANT name: PROTEIN O-MANNOSYLTRANSFERASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MANT - id: FBgg0001329 symbol: MANT-U name: UNCLASSIFIED MANNOSYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MANT - id: FBgg0001332 symbol: CYDA name: CYTIDINE DEAMINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DEAM - id: FBgg0001333 symbol: DEA-U name: UNCLASSIFIED DEAMINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DEAM - id: FBgg0001335 symbol: CNHNP-U name: UNCLASSIFIED CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDINES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHCAN - id: FBgg0001336 symbol: CNHLAN name: CARBON-NITROGEN HYDROLASES OF LINEAR AMIDINES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHNP - id: FBgg0001337 symbol: CNHCA name: CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHNP - id: FBgg0001339 symbol: ADA name: ADENOSINE DEAMINASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DEAM - id: FBgg0001340 symbol: OSTA name: OLIGOSACCHARYL TRANSFERASE A COMPLEX source: gene_group n_members: 9 decision: SUBSUMED module: oligosaccharyltransferase_complex inherited_from: OST-C - id: FBgg0001341 symbol: DPM name: DOLICHOL-PHOSPHATE-MANNOSE SYNTHASE COMPLEX source: gene_group n_members: 3 decision: EXISTING_MODULE module: dolichol_phosphate_sugar_donor_supply - id: FBgg0001342 symbol: HSC name: HEDGEHOG SIGNALING COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_hedgehog_signaling - id: FBgg0001343 symbol: CNHLA-U name: UNCLASSIFIED CARBON-NITROGEN HYDROLASES OF LINEAR AMIDES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001344 symbol: HSP100 name: HEAT SHOCK PROTEIN 100 CHAPERONES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0001345 symbol: MAN name: MANNOSIDASES source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0001346 symbol: B-MAN name: BETA-MANNOSIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MAN - id: FBgg0001347 symbol: B-GLR name: BETA-GLUCURONIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0001348 symbol: AMY name: AMYLASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0001349 symbol: A-GLUS name: ALPHA-GLUCOSIDASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLUS - id: FBgg0001350 symbol: B-GLUS name: BETA-GLUCOSIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLUS - id: FBgg0001351 symbol: GLUS name: GLUCOSIDASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0001352 symbol: NGH name: N-GLYCOSYL HYDROLASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH - id: FBgg0001353 symbol: OGH name: O-GLYCOSYL HYDROLASES source: gene_group n_members: 82 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GH - id: FBgg0001354 symbol: OGH-U name: UNCLASSIFIED O-GLYCOSYL HYDROLASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OGH - id: FBgg0001355 symbol: NUBCK name: NUCLEOBASE-CONTAINING COMPOUND KINASES source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0001356 symbol: PNHK name: POLYNUCLEOTIDE 5'-HYDROXYL-KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUBCK - id: FBgg0001357 symbol: ETH name: HYDROLASES ACTING ON ETHER BONDS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001358 symbol: C-CHYD name: ACID CARBON-CARBON HYDROLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001359 symbol: S-NHYD name: ACID SULFUR-NITROGEN HYDROLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001360 symbol: EPH name: EPOXIDE HYDROLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EHYD - id: FBgg0001362 symbol: EHYD-U name: UNCLASSIFIED ETHER HYDROLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EHYD - id: FBgg0001363 symbol: DNA-GLY name: DNA N-GLYCOSYLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NGH - id: FBgg0001364 symbol: EHYD name: ETHER HYDROLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ETH - id: FBgg0001365 symbol: ADP-RGH name: PROTEIN ADP-RIBOSYL HYDROLASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NGH - id: FBgg0001366 symbol: PLA1 name: PHOSPHOLIPASES A1 source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001367 symbol: ATRNAH name: PEPTIDYL-TRNA HYDROLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001368 symbol: GLLAC name: GLUCONOLACTONASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001369 symbol: CEBH name: CARBOXYLIC ESTER HYDROLASES source: gene_group n_members: 136 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001371 symbol: TRLIP name: TRIGLYCERIDE LIPASES source: gene_group n_members: 55 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001372 symbol: EBH name: ESTER BOND HYDROLASES source: gene_group n_members: 485 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001373 symbol: ATRNAEH name: AMINOACYL-TRNA EDITING HYDROLASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001375 symbol: CEBH-U name: UNCLASSIFIED CARBOXYLIC ESTER HYDROLASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001376 symbol: AGLP name: ACYLGLYCEROL LIPASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001377 symbol: PLC name: PHOSPHOLIPASES C source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PDH - id: FBgg0001378 symbol: SMASE name: SPHINGOMYELINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PDH - id: FBgg0001379 symbol: LPL name: LYSOPHOSPHOLIPASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001381 symbol: WRN name: WIRINS source: gene_group n_members: 37 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001382 symbol: KLG name: KLINGON SUBFAMILY OF WIRINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001383 symbol: LAC name: LACHESIN SUBFAMILY OF WIRINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: WRN - id: FBgg0001384 symbol: MCV-ATPS name: MITOCHONDRIAL COMPLEX V - ATP SYNTHASES source: gene_group n_members: 3 decision: SUBSUMED module: mitochondrial_complex_v inherited_from: MCV-F1 - id: FBgg0001385 symbol: MTPP name: MICROTUBULE PLUS END POLYMERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRFS - id: FBgg0001386 symbol: MCI-C name: MITOCHONDRIAL COMPLEX I - CORE SUBUNITS source: gene_group n_members: 19 decision: SUBSUMED module: mitochondrial_complex_i_core inherited_from: MCI - id: FBgg0001387 symbol: MCI-A name: MITOCHONDRIAL COMPLEX I - ACCESSORY SUBUNITS source: gene_group n_members: 31 decision: SUBSUMED module: mitochondrial_complex_i_core inherited_from: MCI - id: FBgg0001388 symbol: ACE name: ANGIOTENSIN-CONVERTING ENZYME-LIKE source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001389 symbol: ACE-DC name: ANGIOTENSIN-CONVERTING ENZYME-LIKE PEPTIDYL-DIPEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ACE - id: FBgg0001390 symbol: ACE-PSEU name: ANGIOTENSIN-CONVERTING PSEUDOENZYMES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ACE - id: FBgg0001391 symbol: PDH name: PHOSPHORIC DIESTER HYDROLASES source: gene_group n_members: 33 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001392 symbol: GPPD name: GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PDH - id: FBgg0001393 symbol: CNPD name: CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PDH - id: FBgg0001394 symbol: PDH-U name: UNCLASSIFIED PHOSPHORIC DIESTER HYDROLASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PDH - id: FBgg0001395 symbol: CYS-DUB name: CYSTEINE-TYPE DEUBIQUITINASES source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DUB - id: FBgg0001396 symbol: MINDY name: MINDY DEUBIQUITINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0001397 symbol: PEPT name: PEPTIDASES source: gene_group n_members: 451 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001398 symbol: APEPT name: ASPARTIC PEPTIDASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001399 symbol: CPEPT name: CYSTEINE PEPTIDASES source: gene_group n_members: 71 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001400 symbol: MPEPT name: METALLOPEPTIDASES source: gene_group n_members: 118 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001401 symbol: SPEPT name: SERINE PEPTIDASES source: gene_group n_members: 231 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001402 symbol: TPEPT name: THREONINE PEPTIDASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001403 symbol: A1P name: A1 ASPARTIC ENDOPEPTIDASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: APEPT - id: FBgg0001404 symbol: A22P name: A22 ASPARTIC ENDOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: APEPT - id: FBgg0001405 symbol: A28P name: A28 ASPARTIC ENDOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: APEPT - id: FBgg0001406 symbol: C1P name: C1 CYSTEINE PEPTIDASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001407 symbol: CALP name: CALPAINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001408 symbol: GGH name: GAMMA-GLUTAMYL HYDROLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001409 symbol: CULP name: UBIQUITIN-LIKE PROTEIN CYSTEINE PROTEASES source: gene_group n_members: 45 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001410 symbol: C13P name: GPI-ANCHOR TRANSAMIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TFTN - id: FBgg0001411 symbol: C15P name: PYROGLUTAMYTL-PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001412 symbol: SSE name: SEPARASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001413 symbol: C69P name: C69 CYSTEINE EXOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001414 symbol: M16P name: M16 METALLOENDOPEPTIDASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001415 symbol: M41P name: ATP-DEPENDENT METALLOENDOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001416 symbol: STE24 name: STE24 METALLOENDOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001417 symbol: M3P name: M3 METALLOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001418 symbol: M8P name: M8 METALLOENDOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MET - id: FBgg0001419 symbol: S2P name: SITE 2 PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001420 symbol: M76P name: M76 METALLOENDOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001421 symbol: M79P name: M79 METALLOENDOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001422 symbol: M1P name: M1 METALLOPEPTIDASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001423 symbol: M14P name: M14 METALLOCARBOXYPEPTIDASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001424 symbol: LAP name: LEUCYL AMINOPEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001425 symbol: M19P name: M19 METALLODIPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001426 symbol: M20P name: M20 METALLOEXOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001427 symbol: M24P name: M24 METALLOEXOPEPTIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001428 symbol: M28P name: M28 METALLOEXOPEPTIDASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001429 symbol: M49P name: M49 METALLODIPEPTIDYL-PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001430 symbol: MULP name: UBIQUITIN-LIKE PROTEIN METALLOPEPTIDASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001431 symbol: S8P name: S8 SERINE PEPTIDASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001432 symbol: S9P name: S9 SERINE PEPTIDASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001433 symbol: S10P name: S10 SERINE CARBOXYPEPTIDASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001434 symbol: S14-16P name: ATP-DEPENDENT SERINE ENDOPEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001435 symbol: S26P name: S26 SERINE ENDOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001436 symbol: S28P name: S28 SERINE EXOPEPTIDASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001437 symbol: S51P name: S51 SERINE DIPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001438 symbol: S81P name: S81 SERINE ISOPEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SPEPT - id: FBgg0001439 symbol: T1P name: PROTEASOME ENDOPEPTIDASES source: gene_group n_members: 7 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM20SB - id: FBgg0001440 symbol: TASP name: TASPASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TPEPT - id: FBgg0001441 symbol: GGT name: GAMMA-GLUTAMYL TRANSPEPTIDASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TPEPT - id: FBgg0001442 symbol: DSUM name: DESUMOYLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CULP - id: FBgg0001443 symbol: CYS-DNED name: CYSTEINE-TYPE DENEDDYLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CULP - id: FBgg0001444 symbol: DUFM name: DEUFMYLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CULP - id: FBgg0001445 symbol: ATG8P name: ATG8 PROTEASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CULP - id: FBgg0001446 symbol: MMP name: MATRIX METALLOPROTEASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MET - id: FBgg0001447 symbol: AST name: ASTACINS source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MET - id: FBgg0001448 symbol: M-DNED name: METALLO-TYPE DENEDDYLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MULP - id: FBgg0001449 symbol: PCON name: PROPROTEIN CONVERTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S8P - id: FBgg0001450 symbol: TPP name: TRIPEPTIDYL PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S8P - id: FBgg0001451 symbol: PPPDE name: PPPDE DEUBIQUITINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0001452 symbol: SPC name: SIGNAL PEPTIDASE COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_signal_peptidase_complex - id: FBgg0001453 symbol: PSM20S name: PROTEASOME CORE SUBUNITS source: gene_group n_members: 25 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM - id: FBgg0001454 symbol: PSM19S name: PROTEASOME REGULATORY PARTICLE SUBUNITS source: gene_group n_members: 25 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM - id: FBgg0001455 symbol: PSM20SA name: PROTEASOME ALPHA SUBUNITS source: gene_group n_members: 12 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM20S - id: FBgg0001456 symbol: PSM20SB name: PROTEASOME BETA SUBUNITS source: gene_group n_members: 13 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM20S - id: FBgg0001457 symbol: PSM20SB-NC name: PROTEASOME NON-CATALYTIC BETA SUBUNITS source: gene_group n_members: 6 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM20SB - id: FBgg0001458 symbol: APENASE name: CLASS II APURINIC OR APYRIMIDINIC ENDONUCLEASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EDNASE - id: FBgg0001460 symbol: DNASE-I name: DEOXYRIBONUCLEASES I source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EDNASE - id: FBgg0001461 symbol: FENS name: FLAP ENDONUCLEASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EDNASE - id: FBgg0001462 symbol: DNASE name: DNA NUCLEASES source: gene_group n_members: 46 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NASE - id: FBgg0001464 symbol: CJEDNASE name: CROSSOVER JUNCTION DNA ENDONUCLEASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EDNASE - id: FBgg0001465 symbol: EDNASE name: DNA ENDONUCLEASES source: gene_group n_members: 33 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNASE - id: FBgg0001466 symbol: XDNASE name: DNA EXONUCLEASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNASE - id: FBgg0001467 symbol: 3-5-XDNASE name: 3'-5' DNA EXONUCLEASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: XDNASE - id: FBgg0001468 symbol: 5-3-XDNASE name: 5'-3' DNA EXONUCLEASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: XDNASE - id: FBgg0001469 symbol: RDRNASE name: RNA-DNA HYBRID RIBONUCLEASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ERNASE - id: FBgg0001471 symbol: RNASE name: RNA NUCLEASES source: gene_group n_members: 68 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NASE - id: FBgg0001473 symbol: RNASE-III name: RIBONUCLEASES III source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ERNASE - id: FBgg0001474 symbol: TRNAIE name: TRNA-INTRON LYASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: POLYA - id: FBgg0001476 symbol: XRNASE name: RNA EXONUCLEASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNASE - id: FBgg0001477 symbol: 3-5-XRNASE name: 3'-5' RNA EXONUCLEASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: XRNASE - id: FBgg0001478 symbol: ERNASE-U name: UNCLASSIFIED RNA ENDONUCLEASES source: gene_group n_members: 38 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ERNASE - id: FBgg0001479 symbol: 5-3-XRNASE name: 5'-3' RNA EXONUCLEASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: XRNASE - id: FBgg0001480 symbol: ERNASE name: RNA ENDONUCLEASES source: gene_group n_members: 49 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNASE - id: FBgg0001481 symbol: NPH name: NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 180 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSENZ - id: FBgg0001482 symbol: C-NPH name: CYSTEINE-TYPE NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NPH - id: FBgg0001483 symbol: M-NPH name: METALLO-TYPE NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 54 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NPH - id: FBgg0001484 symbol: S-NPH name: SERINE-TYPE NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 97 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NPH - id: FBgg0001485 symbol: T-NPH name: THREONINE-TYPE NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NPH - id: FBgg0001486 symbol: C1-NPH name: C1 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001487 symbol: CALP-NPH name: CALPAIN NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001488 symbol: C19-NPH name: C19 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001489 symbol: C26-NPH name: C26 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001490 symbol: C48-NPH name: C48 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001491 symbol: C110-NPH name: C110 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C-NPH - id: FBgg0001492 symbol: M1-NPH name: M1 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001493 symbol: M3-NPH name: M3 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001494 symbol: M12-NPH name: M12 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001495 symbol: M14-NPH name: M14 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001496 symbol: M16-NPH name: M16 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001497 symbol: S-LAP name: SPERM LEUCYL AMINOPEPTIDASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001498 symbol: M19-NPH name: M19 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001500 symbol: M24-NPH name: M24 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001502 symbol: M48-NPH name: M48 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001503 symbol: M67-NPH name: M67 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M-NPH - id: FBgg0001504 symbol: S9-NPH name: S9 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S-NPH - id: FBgg0001505 symbol: S33-NPH name: S33 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S-NPH - id: FBgg0001506 symbol: S60-NPH name: S60 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S-NPH - id: FBgg0001507 symbol: S81-NPH name: S81 NON-PEPTIDASE HOMOLOGS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S-NPH - id: FBgg0001508 symbol: QC name: GLUTAMINYL CYCLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAGT - id: FBgg0001511 symbol: C1 name: PEPTIDASE FAMILY C1 source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001512 symbol: C2 name: PEPTIDASE FAMILY C2 source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001513 symbol: C19 name: PEPTIDASE FAMILY C19 source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001514 symbol: C26 name: PEPTIDASE FAMILY C26 source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001515 symbol: C48 name: PEPTIDASE FAMILY C48 source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001516 symbol: M1 name: PEPTIDASE FAMILY M1 source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001517 symbol: M3 name: PEPTIDASE FAMILY M3 source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001518 symbol: M12 name: PEPTIDASE FAMILY M12 source: gene_group n_members: 22 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001519 symbol: M14 name: PEPTIDASE FAMILY M14 source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001520 symbol: M16 name: PEPTIDASE FAMILY M16 source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001521 symbol: M17 name: PEPTIDASE FAMILY M17 source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001522 symbol: M19 name: PEPTIDASE FAMILY M19 source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001523 symbol: M20 name: PEPTIDASE FAMILY M20 source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001524 symbol: M24 name: PEPTIDASE FAMILY M24 source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001525 symbol: M28 name: PEPTIDASE FAMILY M28 source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001526 symbol: M48 name: PEPTIDASE FAMILY M48 source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001527 symbol: M67 name: PEPTIDASE FAMILY M67 source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001528 symbol: S9 name: PEPTIDASE FAMILY S9 source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001529 symbol: S81 name: PEPTIDASE FAMILY S81 source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001530 symbol: CTS name: CATHEPSINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C1P - id: FBgg0001531 symbol: C1BP name: C1B CYSTEINE PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: C1P - id: FBgg0001532 symbol: METAP name: METHIONYL AMINOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M24P - id: FBgg0001533 symbol: M24BP name: M24B METALLOEXOPEPTIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: M24P - id: FBgg0001534 symbol: S9AP name: S9A SERINE OLIGOPEPTIDASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S9P - id: FBgg0001535 symbol: DPPIV name: DIPEPTIDYL PEPTIDASES IV source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: S9P - id: FBgg0001536 symbol: ADAMTSL name: ADAMTS LIKE source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001537 symbol: SHYD name: THIOLESTER HYDROLASES source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001538 symbol: PHYD name: PALMITOYL-(PROTEIN) HYDROLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SHYD - id: FBgg0001539 symbol: CHYD name: ACYL-COA HYDROLASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SHYD - id: FBgg0001540 symbol: SHYD-U name: UNCLASSIFIED THIOLESTER HYDROLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SHYD - id: FBgg0001541 symbol: SEHYD-U name: UNCLASSIFIED SULFURIC ESTER HYDROLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SEHYD - id: FBgg0001542 symbol: NAG6S name: N-ACETYLGLUCOSAMINE-6-SULFATASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SEHYD - id: FBgg0001543 symbol: SEHYD name: SULFURIC ESTER HYDROLASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001544 symbol: NASE name: NUCLEASES (HYDROLYTIC MECHANISM) source: gene_group n_members: 104 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001545 symbol: NASE-U name: UNCLASSIFIED NUCLEASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NASE - id: FBgg0001546 symbol: TPN-C name: TROPONIN COMPLEX SUBUNITS source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_troponin_complex - id: FBgg0001547 symbol: TPNC name: TROPONIN C ISOFORMS source: gene_group n_members: 5 decision: SUBSUMED module: dmel_troponin_complex inherited_from: TPN-C - id: FBgg0001548 symbol: TPNI name: TROPONIN I ISOFORMS source: gene_group n_members: 1 decision: SUBSUMED module: dmel_troponin_complex inherited_from: TPN-C - id: FBgg0001549 symbol: TPNT name: TROPONIN T ISOFORMS source: gene_group n_members: 1 decision: SUBSUMED module: dmel_troponin_complex inherited_from: TPN-C - id: FBgg0001550 symbol: RLC name: RISC LOADING COMPLEXES source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_risc_loading_complexes - id: FBgg0001551 symbol: miRLC name: miRNA RISC LOADING COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_risc_loading_complexes inherited_from: RLC - id: FBgg0001552 symbol: siRLC name: siRNA RISC-LOADING COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_risc_loading_complexes inherited_from: RLC - id: FBgg0001553 symbol: aRLC name: ALTERNATIVE siRNA RISC-LOADING COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_risc_loading_complexes inherited_from: RLC - id: FBgg0001554 symbol: TOPI name: DNA TOPOISOMERASES TYPE I source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TOP - id: FBgg0001555 symbol: TOPII name: DNA TOPOISOMERASES TYPE II source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TOP - id: FBgg0001556 symbol: RPN name: PROTEASOME REGULATORY PARTICLE NON-ATPASES source: gene_group n_members: 16 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM19S - id: FBgg0001557 symbol: RPT name: PROTEASOME REGULATORY PARTICLE ATPASES source: gene_group n_members: 9 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM19S - id: FBgg0001558 symbol: VHA-V1-CAT name: VACUOLAR ATPASE V1 DOMAIN CATALYTIC SUBUNITS source: gene_group n_members: 3 decision: SUBSUMED module: dmel_vacuolar_atpase inherited_from: VHA-V1 - id: FBgg0001559 symbol: VHA-V1-NONCAT name: VACUOLAR ATPASE V1 DOMAIN NON-CATALYTIC SUBUNITS source: gene_group n_members: 11 decision: SUBSUMED module: dmel_vacuolar_atpase inherited_from: VHA-V1 - id: FBgg0001560 symbol: TNF name: TNFalpha-EIGER SIGNALING PATHWAY source: signaling_pathway n_members: 23 decision: NEW_MODULE module: dmel_eiger_tnf_signaling - id: FBgg0001561 symbol: TNF-C name: TNFalpha-EIGER SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 12 decision: SUBSUMED module: dmel_eiger_tnf_signaling inherited_from: TNF - id: FBgg0001562 symbol: TNF-N name: NEGATIVE REGULATORS OF TNFalpha-EIGER SIGNALING PATHWAY source: signaling_pathway n_members: 5 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001563 symbol: TNF-P name: POSITIVE REGULATORS OF TNFalpha-EIGER SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001564 symbol: TNFR name: TUMOR NECROSIS FACTOR RECEPTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001565 symbol: SRPGTP name: SIGNAL RECOGNITION PARTICLE GTPASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0001566 symbol: NS name: NUCLEOSTEMINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0001567 symbol: TRGTP name: TRANSLATIONAL GTPASES source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0001569 symbol: GTPASE name: GTPASES source: gene_group n_members: 146 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NTPASE - id: FBgg0001571 symbol: DLGTP name: DYNAMIN-LIKE GTPASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0001572 symbol: GTPASE-U name: UNCLASSIFIED GTPASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0001573 symbol: AAH name: ACID ANHYDRIDE HYDROLASES source: gene_group n_members: 298 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001575 symbol: NTPASE name: NUCLEOSIDE TRIPHOSPHATE PHOSPHATASES source: gene_group n_members: 261 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001576 symbol: ATPASE name: ATPASES source: gene_group n_members: 116 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NTPASE - id: FBgg0001577 symbol: ATPASETT name: ATPASE-COUPLED TRANSLOCASES source: gene_group n_members: 71 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRNL - id: FBgg0001578 symbol: MMOT name: MICROTUBULE MOTORS source: gene_group n_members: 37 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCISO - id: FBgg0001580 symbol: RFC-ATPASE name: RFC COMPLEX ATPASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001581 symbol: HEL name: HELICASES source: gene_group n_members: 83 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NCISO - id: FBgg0001582 symbol: DNAHEL name: DNA HELICASES source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEL - id: FBgg0001583 symbol: MCM name: MCM FAMILY HELICASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNAHEL - id: FBgg0001584 symbol: RAD3 name: RAD3/XPD-LIKE DNA HELICASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNAHEL - id: FBgg0001585 symbol: RECQ name: RECQ-LIKE DNA HELICASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNAHEL - id: FBgg0001586 symbol: RUVB name: RUVB-LIKE DNA HELICASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNAHEL - id: FBgg0001587 symbol: SNF2 name: SNF2-LIKE CHROMATIN REMODELERS source: gene_group n_members: 16 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001588 symbol: DNAHEL-U name: UNCLASSIFIED DNA HELICASES source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DNAHEL - id: FBgg0001589 symbol: RNAHEL name: RNA HELICASES source: gene_group n_members: 59 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HEL - id: FBgg0001590 symbol: DEAD name: DEAD-BOX RNA HELICASES source: gene_group n_members: 33 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAHEL - id: FBgg0001591 symbol: DEAH name: DEAH-BOX RNA HELICASES source: gene_group n_members: 13 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAHEL - id: FBgg0001592 symbol: SKI2 name: SKI2-LIKE RNA HELICASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAHEL - id: FBgg0001593 symbol: UPF1 name: UPF1-LIKE RNA HELICASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAHEL - id: FBgg0001594 symbol: RNAHEL-U name: UNCLASSIFIED RNA HELICASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RNAHEL - id: FBgg0001595 symbol: MSATPASE name: MICROTUBULE SEVERING ATPASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PCISO - id: FBgg0001596 symbol: AHEL name: ANNEALING HELICASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NCISO - id: FBgg0001597 symbol: RAD51 name: RAD51-LIKE ATPASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DDS - id: FBgg0001598 symbol: MUTL name: MUTL ATPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DDS - id: FBgg0001599 symbol: MUTS name: MUTS ATPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DDS - id: FBgg0001600 symbol: ATPASE-U name: UNCLASSIFIED ATPASES source: gene_group n_members: 27 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001601 symbol: ACYP name: ACYLPHOSPHATASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001602 symbol: NDPASE name: NUCLEOSIDE DIPHOSPHATE PHOSPHATASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001603 symbol: NTPDPASE name: NUCLEOSIDE TRIPHOSPHATE DIPHOSPHATASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001606 symbol: DECAP name: RNA DECAPPING ENZYMES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001607 symbol: UDP-PP name: UDP-SUGAR DIPHOSPHATASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001608 symbol: ADPRASE name: ADP-RIBOSE DIPHOSPHATASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001609 symbol: AAH-U name: UNCLASSIFIED ACID ANHYDRIDE HYDROLASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0001610 symbol: MYO-M name: MYOSIN MOTORS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: MYO - id: FBgg0001611 symbol: MYO-NM name: NON-MOTOR MYOSINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: MYO - id: FBgg0001612 symbol: CMG name: CMG COMPLEX source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_replication_origin_licensing_activation - id: FBgg0001613 symbol: GINS name: GINS COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_replication_origin_licensing_activation - id: FBgg0001614 symbol: MCM2-7 name: MCM2-7 COMPLEX source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_replication_origin_licensing_activation - id: FBgg0001616 symbol: EBH-U name: UNCLASSIFIED ESTER BOND HYDROLASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EBH - id: FBgg0001618 symbol: ECKL name: ECDYSTEROID KINASE-LIKE source: gene_group n_members: 51 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0001619 symbol: BORC name: BLOC1-RELATED COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_bloc_borc_complexes - id: FBgg0001620 symbol: AEST name: ARYLESTERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001621 symbol: CTD name: CTD FAMILY PROTEIN SERINE/THREONINE PHOSPHATASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HAD-PP - id: FBgg0001622 symbol: EYA name: EYA FAMILY PROTEIN TYROSINE PHOSPHATASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTP - id: FBgg0001624 symbol: FAR name: FATTY ACYL-COA REDUCTASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAONAD - id: FBgg0001625 symbol: GAPDH name: GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAONAD - id: FBgg0001626 symbol: OXRAONAD-U name: UNCLASSIFIED ALDEHYDE OR OXO OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAONAD - id: FBgg0001627 symbol: DGAT name: DIACYLGLYCEROL O-ACYLTRANSFERASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0001628 symbol: NACTT name: N-ACETYLTRANSFERASES source: gene_group n_members: 43 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ACTT - id: FBgg0001629 symbol: AANAT name: ARYLALKYLAMINE N-ACETYLTRANSFERASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NACTT - id: FBgg0001630 symbol: NACTT-U name: UNCLASSIFIED N-ACETYLTRANSFERASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NACTT - id: FBgg0001631 symbol: OACTT name: O-ACETYLTRANSFERASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ACTT - id: FBgg0001632 symbol: CACTT name: C-ACETYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ACTT - id: FBgg0001633 symbol: SACTT name: S-ACETYLTRANSFERASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ACTT - id: FBgg0001634 symbol: TCTC name: THREONYL-CARBAMOYL TRANSFERASE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_threonylcarbamoyl_transferase_complex - id: FBgg0001635 symbol: PHP name: PROTEIN HISTIDINE PHOSPHATASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPASE - id: FBgg0001636 symbol: DEAM name: DEAMINASES source: gene_group n_members: 17 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHNP - id: FBgg0001638 symbol: PDF name: PEPTIDE DEFORMYLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001639 symbol: P-TEFB name: POSITIVE TRANSCRIPTION ELONGATION FACTOR COMPLEX B source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001640 symbol: PFDN name: PREFOLDIN COMPLEX source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_prefoldin - id: FBgg0001641 symbol: 7SKRNP name: 7SK SMALL NUCLEAR RIBONUCLEOPROTEIN source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001642 symbol: LARP name: LA-RELATED PROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001644 symbol: IRM name: IRRE CELL RECOGNITION MODULE CELL ADHESION MOLECULES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001645 symbol: NCBAP name: NON-CANONICAL BRAHMA ASSOCIATED PROTEINS COMPLEX source: gene_group n_members: 7 decision: SUBSUMED module: dmel_brahma_complexes inherited_from: BRM - id: FBgg0001646 symbol: RNAP name: NUCLEAR RNA POLYMERASE COMPLEXES source: gene_group n_members: 31 decision: NEW_MODULE module: dmel_nuclear_rna_polymerases - id: FBgg0001647 symbol: RNAPI name: RNA POLYMERASE I source: gene_group n_members: 13 decision: SUBSUMED module: dmel_nuclear_rna_polymerases inherited_from: RNAP - id: FBgg0001648 symbol: RNAPIII name: RNA POLYMERASE III source: gene_group n_members: 17 decision: SUBSUMED module: dmel_nuclear_rna_polymerases inherited_from: RNAP - id: FBgg0001649 symbol: IPPS name: ISOPRENYL PYROPHOSPHATE SYNTHASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTF - id: FBgg0001650 symbol: PPTF name: PROTEIN PRENYLTRANSFERASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTF - id: FBgg0001651 symbol: APTF name: AROMATIC PRENYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTF - id: FBgg0001652 symbol: PRP name: PROTEIN ARGININE PHOSPHATASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PPASE - id: FBgg0001653 symbol: ML name: MD-2-RELATED LIPID-RECOGNITION PROTEINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001654 symbol: SLC52 name: SLC52 FAMILY OF RIBOFLAVIN TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001655 symbol: SLC10 name: SLC10 FAMILY OF SODIUM-BILE ACID CO-TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001656 symbol: SLC49 name: SLC49 FAMILY OF FLVCR-RELATED TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001657 symbol: SLC42 name: SLC42 FAMILY AMMONIUM TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001658 symbol: SLC66 name: SLC66 FAMILY OF LYSOSOMAL AMINO ACID TRANSPORTERS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001659 symbol: SLC23 name: SLC23 FAMILY OF ASCORBIC ACID TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001660 symbol: SLC57 name: SLC57 FAMILY OF NIPA-LIKE MAGNESIUM TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001661 symbol: SLC56 name: SLC56 FAMILY OF SIDEROFLEXINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001662 symbol: SLC58 name: SLC58 FAMILY OF MAGT-LIKE MAGNESIUM TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001663 symbol: SLC65 name: SLC65 FAMILY OF NPC-TYPE CHOLESTEROL TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001664 symbol: SLC55 name: SLC55 FAMILY OF MITOCHONDRIAL CATION/PROTON EXCHANGERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001665 symbol: SLC53 name: SLC53 FAMILY OF PHOSPHATE CARRIERS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001666 symbol: SLC54 name: SLC54 FAMILY OF MITOCHONDRIAL PYRUVATE CARRIERS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001667 symbol: SLC63 name: SLC63 FAMILY OF SPHINGOSINE PHOSPHATE TRANSPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001668 symbol: SLC64 name: SLC64 FAMILY OF GOLGI CA2+/H+ EXCHANGERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001669 symbol: BASP name: BETA-ASPARTYL PEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TPEPT - id: FBgg0001670 symbol: NTASE name: NUCLEOTIDASES source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0001671 symbol: CARBP name: CARBOHYDRATE PHOSPHATASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0001672 symbol: GLUS-U name: UNCLASSIFIED GLUCOSIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLUS - id: FBgg0001673 symbol: RNASEP name: RNASE P COMPLEXES source: gene_group n_members: 13 decision: NEW_MODULE module: dmel_rnase_p_mrp - id: FBgg0001674 symbol: RNASEP-M name: MITOCHONDRIAL RNASE P COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_rnase_p_mrp inherited_from: RNASEP - id: FBgg0001675 symbol: RNASEP-N name: NUCLEAR RNASE P COMPLEX source: gene_group n_members: 10 decision: SUBSUMED module: dmel_rnase_p_mrp inherited_from: RNASEP - id: FBgg0001676 symbol: RNASEMRP name: RNASE MRP COMPLEX source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_rnase_p_mrp - id: FBgg0001677 symbol: GH99 name: ENDO-ALPHA MANNOSIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: A-MAN - id: FBgg0001679 symbol: OTU-DUB-S name: SERINE-TYPE OTU DEUBIQUITINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: DUB - id: FBgg0001680 symbol: OTU-DUB-C name: CYSTEINE-TYPE OTU DEUBIQUITINASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0001681 symbol: CDC25 name: CDC25 FAMILY PROTEIN PHOSPHATASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PTP - id: FBgg0001683 symbol: POMT1-2C name: POMT1-POMT2 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_protein_o_glycosylation - id: FBgg0001684 symbol: MCIII-S name: MITOCHONDRIAL COMPLEX III - SUPERNUMERARY SUBUNITS source: gene_group n_members: 10 decision: SUBSUMED module: mitochondrial_complex_iii inherited_from: MCIII - id: FBgg0001685 symbol: LAMTOR name: RAGULATOR COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_torc1_nutrient_sensing - id: FBgg0001686 symbol: MCV-CS name: MITOCHONDRIAL COMPLEX V - CENTRAL STALK source: gene_group n_members: 4 decision: SUBSUMED module: mitochondrial_complex_v inherited_from: MCV-F1 - id: FBgg0001687 symbol: MCIV-S name: MITOCHONDRIAL COMPLEX IV - SUPERNUMERARY SUBUNITS source: gene_group n_members: 19 decision: SUBSUMED module: mitochondrial_complex_iv inherited_from: MCIV - id: FBgg0001688 symbol: RDH-NADP name: ALL-TRANS-RETINOL DEHYDROGENASES (NADP-DEPENDENT) source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AKR - id: FBgg0001689 symbol: ALDR name: ALDOSE REDUCTASES source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AKR - id: FBgg0001690 symbol: AKR-U name: UNCLASSIFIED ALCOHOL DEHYDROGENASES (NADP-DEPENDENT) source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AKR - id: FBgg0001691 symbol: OXRCHNHO name: CH-NH OXIDOREDUCTASES, OXYGEN AS ACCEPTOR source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHNH - id: FBgg0001692 symbol: ASOX name: ASCORBATE OXIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRDPO - id: FBgg0001693 symbol: CYB561 name: CYTOCHROMES B561 source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRMI - id: FBgg0001694 symbol: CYP450-CYP2 name: CYTOCHROME P450 - CYP2 CLAN source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYP450 - id: FBgg0001695 symbol: CYP450-CYP3 name: CYTOCHROME P450 - CYP3 CLAN source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYP450 - id: FBgg0001696 symbol: CYP450-CYP4 name: CYTOCHROME P450 - CYP4 CLAN source: gene_group n_members: 32 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYP450 - id: FBgg0001697 symbol: CYP450-MITO name: CYTOCHROME P450 - MITO CLAN source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYP450 - id: FBgg0001698 symbol: TRX name: THIOREDOXINS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001699 symbol: GRX name: GLUTAREDOXINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSD - id: FBgg0001700 symbol: OXRSD-U name: UNCLASSIFIED SULFUR OXIDOREDUCTASES, DISULFIDE AS ACCEPTOR source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSD - id: FBgg0001701 symbol: TRXR name: THIOREDOXIN REDUCTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSNAD - id: FBgg0001702 symbol: OXRSNAD-U name: UNCLASSIFIED SULFUR OXIDOREDUCTASES, NAD(P) AS ACCEPTOR source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSNAD - id: FBgg0001703 symbol: OXRSQ name: SULFUR OXIDOREDUCTASES, QUINONE AS ACCEPTOR source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001704 symbol: DHAR name: DEHYDROASCORBATE REDUCTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSQ - id: FBgg0001705 symbol: SQOR name: SULFIDE-QUINONE OXIOREDUCTASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSQ - id: FBgg0001707 symbol: DESAT name: DESATURASES source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001708 symbol: MOOX name: MONOOXYGENASES source: gene_group n_members: 111 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001709 symbol: DIOX name: DIOXYGENASES source: gene_group n_members: 62 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0001710 symbol: LMDH name: L-MALATE DEHYDROGENASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MDH - id: FBgg0001711 symbol: MEN name: MALIC ENZYMES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MDH - id: FBgg0001712 symbol: BCKDH name: BRANCHED-CHAIN KETO ACID DEHYDROGENASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAOD - id: FBgg0001713 symbol: OGDH name: OXOGLUTARATE DEHYDROGENASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAOD - id: FBgg0001714 symbol: PYDH name: PYRUVATE DEHYDROGENASES (ACETYL-TRANSFERRING) source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAOD - id: FBgg0001715 symbol: ENZ name: ENZYMES source: gene_group n_members: 3715 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. - id: FBgg0001716 symbol: SCAVL name: SCAVENGER-LIKE RECEPTORS source: gene_group n_members: 30 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: TM-R - id: FBgg0001717 symbol: SCAV-C name: CLASS C SCAVENGER RECEPTORS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: SCAV - id: FBgg0001718 symbol: SCAV name: SCAVENGER RECEPTORS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: SCAVL - id: FBgg0001719 symbol: SCAV-B name: CLASS B SCAVENGER RECEPTORS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: SCAV - id: FBgg0001720 symbol: TRNL name: TRANSLOCASES source: gene_group n_members: 105 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ENZ - id: FBgg0001721 symbol: TRNL-OXR name: OXIDOREDUCTASE-COUPLED TRANSLOCASES source: gene_group n_members: 34 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRNL - id: FBgg0001723 symbol: DISL name: DISLOCASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001724 symbol: LEC name: LITTLE ELONGATION COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001725 symbol: TEFC name: TRANSCRIPTION ELONGATION FACTOR COMPLEXES source: gene_group n_members: 39 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0001726 symbol: PAF1C name: RNA POLYMERASE-ASSOCIATED FACTOR 1 COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001727 symbol: NELF name: NEGATIVE ELONGATION FACTOR source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001728 symbol: DSIF name: DRB SENSITIVITY-INDUCING FACTOR COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001729 symbol: SEC name: SUPER ELONGATION COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001730 symbol: MCISO name: MACROMOLECULAR CONFORMATION ISOMERASES source: gene_group n_members: 152 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ISO - id: FBgg0001731 symbol: PCISO name: POLYPEPTIDE CONFORMATION ISOMERASES source: gene_group n_members: 63 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MCISO - id: FBgg0001732 symbol: VCB name: VCB COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_vcb_ubiquitin_ligase - id: FBgg0001733 symbol: ELO name: ELONGIN COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0001734 symbol: GILT name: GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRSD - id: FBgg0001735 symbol: KPC name: KIP1 UBIQUITINATION-PROMOTING COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_kpc_ubiquitin_ligase - id: FBgg0001736 symbol: EDNASE-U name: UNCLASSIFIED DNA ENDONUCLEASES source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: EDNASE - id: FBgg0001737 symbol: ACPC name: F-ACTIN CAPPING PROTEIN COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_f_actin_capping_protein - id: FBgg0001738 symbol: BHAD name: BETA HYDROXY ACID DEHYDROGENASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0001739 symbol: NTRLIP name: NEUTRAL TRIGLYCERIDE LIPASES source: gene_group n_members: 28 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRLIP - id: FBgg0001740 symbol: ATRLIP name: ACID TRIGLYCERIDE LIPASES source: gene_group n_members: 23 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRLIP - id: FBgg0001741 symbol: TRLIP-U name: UNCLASSIFIED TRIGLYCERIDE LIPASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TRLIP - id: FBgg0001742 symbol: M100 name: M100 METALLOENDOPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MPEPT - id: FBgg0001743 symbol: PFC name: ATP-DEPENDENT PROTEIN FOLDING CHAPERONES source: gene_group n_members: 29 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001744 symbol: DDS name: ATP-DEPENDENT DNA DAMAGE SENSORS source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001745 symbol: FCC name: ATP-DEPENDENT FE-S CLUSTER CHAPERONES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASE - id: FBgg0001747 symbol: ADAC name: ADA COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_gcn5_acetyltransferase_complexes inherited_from: GCN5 - id: FBgg0001748 symbol: GCN5 name: GCN5-CONTAINING COMPLEXES source: gene_group n_members: 32 decision: NEW_MODULE module: dmel_gcn5_acetyltransferase_complexes - id: FBgg0001749 symbol: CHAT name: CHAT COMPLEX source: gene_group n_members: 5 decision: SUBSUMED module: dmel_gcn5_acetyltransferase_complexes inherited_from: GCN5 - id: FBgg0001750 symbol: CGLR name: CGAS-LIKE RECEPTORS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUTF - id: FBgg0001751 symbol: UBL name: UBIQUITIN-LIKE PROTEINS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001752 symbol: LSP name: LARVAL SERUM PROTEIN SUBUNITS source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_larval_serum_protein_hexamers - id: FBgg0001753 symbol: SUMO name: SUMO PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001754 symbol: NEDD8 name: NEDD8 PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001755 symbol: URM1 name: URM1 PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001756 symbol: UFM1 name: UFM1 PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001757 symbol: ATG8 name: ATG8 PROTEINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001758 symbol: ATG12 name: ATG12 PROTEINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: UBL - id: FBgg0001759 symbol: TAGLN name: TRANSGELINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001760 symbol: PAR name: PAR COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_epithelial_polarity_complexes - id: FBgg0001761 symbol: SRNPS name: SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEXES source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_small_nucleolar_rnps - id: FBgg0001762 symbol: SCRIBC name: SCRIBBLE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_epithelial_polarity_complexes - id: FBgg0001763 symbol: CRBC name: CRUMBS COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_epithelial_polarity_complexes - id: FBgg0001764 symbol: H-ACA name: H/ACA SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_small_nucleolar_rnps inherited_from: SRNPS - id: FBgg0001765 symbol: C-DRNP name: C/D SMALL NUCLEOLAR RIBONUCLEOPROTEIN COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_small_nucleolar_rnps inherited_from: SRNPS - id: FBgg0001767 symbol: LDCPEPT name: L,D-CARBOXYPEPTIDASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001768 symbol: G-TUSC name: GAMMA-TUBULIN SMALL COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_gamma_tubulin_complexes inherited_from: G-TUC - id: FBgg0001769 symbol: G-TUC name: GAMMA-TUBULIN COMPLEXES source: gene_group n_members: 11 decision: NEW_MODULE module: dmel_gamma_tubulin_complexes - id: FBgg0001770 symbol: T-G-TURC name: TESTIS-SPECIFIC GAMMA-TUBULIN RING COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_gamma_tubulin_complexes inherited_from: G-TUC - id: FBgg0001771 symbol: G-TURC name: GAMMA-TUBULIN RING COMPLEX source: gene_group n_members: 8 decision: SUBSUMED module: dmel_gamma_tubulin_complexes inherited_from: G-TUC - id: FBgg0001773 symbol: ACOAL name: ACETATE-COA LIGASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CSLIG - id: FBgg0001774 symbol: RDC name: RHINO-DEADLOCK-CUTOFF COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_pirna_nuclear_complexes - id: FBgg0001776 symbol: HPX name: HEME PEROXIDASES source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PX - id: FBgg0001777 symbol: TM2D name: TM2 DOMAIN CONTAINING PROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001778 symbol: AGO name: ARGONAUTE ENDORIBONUCLEASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ERNASE - id: FBgg0001779 symbol: ULPP name: UBIQUITIN-LIKE PROTEIN PEPTIDASES source: gene_group n_members: 54 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PEPT - id: FBgg0001780 symbol: DNED name: DENEDDYLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ULPP - id: FBgg0001781 symbol: LSP1 name: LSP1 COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_larval_serum_protein_hexamers - id: FBgg0001782 symbol: NCISO name: NUCLEIC ACID CONFORMATION ISOMERASES source: gene_group n_members: 89 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: MCISO - id: FBgg0001783 symbol: OTOPL name: OTOPETRIN-LIKE PROTON CHANNELS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CHEMOR - id: FBgg0001784 symbol: DSO name: DAISHO PEPTIDES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0001785 symbol: BARA name: BARAMICINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001786 symbol: NACS name: NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNITS source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_nascent_polypeptide_associated_complex - id: FBgg0001787 symbol: NACA name: NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX ALPHA SUBUNITS source: gene_group n_members: 2 decision: SUBSUMED module: dmel_nascent_polypeptide_associated_complex inherited_from: NACS - id: FBgg0001788 symbol: NACB name: NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX BETA SUBUNITS source: gene_group n_members: 7 decision: SUBSUMED module: dmel_nascent_polypeptide_associated_complex inherited_from: NACS - id: FBgg0001789 symbol: RSF name: REMODELING AND SPACING FACTOR COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_iswi_complexes inherited_from: ISWI - id: FBgg0001790 symbol: SWR1 name: SWR1 COMPLEX source: gene_group n_members: 12 decision: NEW_MODULE module: dmel_swr1_domino_complex - id: FBgg0001791 symbol: KAT-U name: UNCLASSIFIED PROTEIN-LYSINE ACETYLTRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KAT - id: FBgg0001792 symbol: CGAS-STING name: CGAS-STING SIGNALING PATHWAY source: signaling_pathway n_members: 7 decision: NEW_MODULE module: dmel_cgas_sting_signaling - id: FBgg0001793 symbol: CGAS-STING-C name: CGAS-STING SIGNALING PATHWAY CORE COMPONENTS source: signaling_pathway n_members: 6 decision: SUBSUMED module: dmel_cgas_sting_signaling inherited_from: CGAS-STING - id: FBgg0001794 symbol: C-SHYD name: CARBON-SULFUR HYDROLASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HYD - id: FBgg0001795 symbol: HSP10 name: HEAT SHOCK PROTEIN 10 CHAPERONINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HSP - id: FBgg0001796 symbol: ARPC3B name: ACTIN-RELATED PROTEIN 2/3 COMPLEX ARPC3B VARIANT source: gene_group n_members: 7 decision: SUBSUMED module: dmel_arp2_3_complex inherited_from: ARPC-C - id: FBgg0001797 symbol: ARPC-C name: ACTIN-RELATED PROTEIN 2/3 COMPLEXES source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_arp2_3_complex - id: FBgg0001798 symbol: PSENZ name: PSEUDOENZYMES source: gene_group n_members: 319 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. - id: FBgg0001799 symbol: COHSN-SOLO-SUNN name: MEIOTIC COHESIN COMPLEX SOLO-SUNN VARIANT source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_cohesin_complexes - id: FBgg0001800 symbol: COHSN-C2M-SA name: MEIOTIC COHESIN COMPLEX C2M-SA VARIANT source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_cohesin_complexes - id: FBgg0001801 symbol: miRISC name: miRNA-INDUCED SILENCING COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_risc_loading_complexes - id: FBgg0001802 symbol: FUSF name: FUSED-SMURF UBIQUITIN LIGASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_fused_smurf_complex - id: FBgg0001803 symbol: PSEU-PP name: PSEUDOPHOSPHATASES source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSENZ - id: FBgg0001804 symbol: CDAC name: CHITIN DEACETYLASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CDA - id: FBgg0001805 symbol: PSCDA name: PSEUDO-CHITIN DEACETYLASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: CDA - id: FBgg0001806 symbol: PSENZ-U name: UNCLASSIFIED PSEUDOENZYMES source: gene_group n_members: 71 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSENZ - id: FBgg0001807 symbol: RYK name: RECEPTOR RELATED TO TYROSINE KINASE source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0001808 symbol: PSEUK-U name: UNCLASSIFIED PSEUDOKINASES source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PSEUK - id: FBgg0001809 symbol: DES-C2 name: BETA CATENIN DESTRUCTION COMPLEX APC2 VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_wnt_tcf_signaling inherited_from: DES - id: FBgg0001810 symbol: DES name: BETA CATENIN DESTRUCTION COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_wnt_tcf_signaling - id: FBgg0001811 symbol: EMPC name: ER MEMBRANE PROTEIN COMPLEXES source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_er_membrane_protein_complex - id: FBgg0001812 symbol: EMC2B name: ER MEMBRANE PROTEIN COMPLEX EMC2B VARIANT source: gene_group n_members: 9 decision: SUBSUMED module: dmel_er_membrane_protein_complex inherited_from: EMPC - id: FBgg0001813 symbol: ESCRT-IB name: ESCRT-I COMPLEX VPS37B VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT-I - id: FBgg0001814 symbol: ESCRT-IA name: ESCRT-I COMPLEX VPS37A VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_escrt_machinery inherited_from: ESCRT-I - id: FBgg0001815 symbol: LSTAU name: LARGE CYTOPLASMIC STAUFEN RNP GRANULES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001816 symbol: ACTMAP name: ACTIN MATURATION PROTEASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CPEPT - id: FBgg0001817 symbol: CEST name: CARBOXYLESTERASES source: gene_group n_members: 25 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CEBH - id: FBgg0001818 symbol: TOT name: TURANDOTS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0001819 symbol: NOC name: NUCLEOLAR COMPLEX ASSOCIATED FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001820 symbol: ELP name: ELONGATOR HOLOENZYME COMPLEX source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_elongator_complex - id: FBgg0001821 symbol: VTD name: VIRAL TEGUMENT-LIKE DEUBIQUITINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CYS-DUB - id: FBgg0001822 symbol: OXRS-U name: UNCLASSIFIED SULFUR GROUP OXIDOREDUCTASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRS - id: FBgg0001823 symbol: TFIIA-S name: GENERAL TRANSCRIPTION FACTOR II A COMPLEX - TFIIA-S VARIANT source: gene_group n_members: 2 decision: SUBSUMED module: dmel_rnapii_general_transcription_factors inherited_from: TFIIA - id: FBgg0001824 symbol: TFIIA-S2 name: GENERAL TRANSCRIPTION FACTOR II A COMPLEX - GERMLINE SPECIFIC VARIANT source: gene_group n_members: 2 decision: SUBSUMED module: dmel_rnapii_general_transcription_factors inherited_from: TFIIA - id: FBgg0001825 symbol: SMC5-6-V name: SMC5/6 COMPLEX - CERV VARIANT source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_smc5_6_complex - id: FBgg0001826 symbol: SEC61T-G2 name: SEC61 TRANSLOCON - SEC61gamma VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_sec61_translocon inherited_from: SEC61TC - id: FBgg0001827 symbol: NATC-T name: N-TERMINAL ACETYLTRANSFERASE C COMPLEX - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_n_terminal_acetyltransferase_complexes inherited_from: NAT-CPX - id: FBgg0001828 symbol: COP9-C name: COP9 SIGNALOSOME COMPLEXES source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_cop9_signalosome - id: FBgg0001829 symbol: COP9-T name: COP9 SIGNALOSOME COMPLEX - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 8 decision: SUBSUMED module: dmel_cop9_signalosome inherited_from: COP9-C - id: FBgg0001830 symbol: SMN-CPX name: SURVIVAL MOTOR NEURON COMPLEX VARIANTS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_smn_complex - id: FBgg0001831 symbol: SMN-C-4B name: SURVIVAL MOTOR NEURON COMPLEX - GEM4B VARIANT source: gene_group n_members: 5 decision: SUBSUMED module: dmel_smn_complex inherited_from: SMN-CPX - id: FBgg0001832 symbol: SMN-C-4C name: SURVIVAL MOTOR NEURON COMPLEX - GEM4C VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_smn_complex inherited_from: SMN-CPX - id: FBgg0001833 symbol: CPC-MIT name: MITOTOIC CHROMOSOMAL PASSENGER COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_chromosomal_passenger_complex inherited_from: CPC - id: FBgg0001834 symbol: CPC-MEI name: MEIOTIC CHROMOSOMAL PASSENGER COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_chromosomal_passenger_complex inherited_from: CPC - id: FBgg0001835 symbol: PHORC-L name: PHO REPRESSIVE COMPLEX - PHOL VARIANT source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0001836 symbol: MCI-U name: MITOCHONDRIAL COMPLEX I source: gene_group n_members: 44 decision: EXISTING_MODULE module: mitochondrial_complex_i_core - id: FBgg0001837 symbol: MCI-T name: MITOCHONDRIAL COMPLEX I - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 45 decision: EXISTING_MODULE module: mitochondrial_complex_i_core - id: FBgg0001838 symbol: PSM26S-T name: 26S PROTEASOME - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 38 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM-V - id: FBgg0001839 symbol: PSM26S name: 26S PROTEASOME source: gene_group n_members: 34 decision: SUBSUMED module: dmel_proteasome inherited_from: PSM-V - id: FBgg0001840 symbol: MCIV-T name: MITOCHONDRIAL COMPLEX IV - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 15 decision: EXISTING_MODULE module: mitochondrial_complex_iv - id: FBgg0001841 symbol: OXPHOS-V name: MITOCHONDRIAL OXPHOS COMPLEX VARIANTS source: gene_group n_members: 117 decision: EXISTING_MODULE module: oxphos - id: FBgg0001842 symbol: MCII-U name: MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) source: gene_group n_members: 4 decision: EXISTING_MODULE module: mitochondrial_complex_ii - id: FBgg0001843 symbol: MCIII-T name: MITOCHONDRIAL COMPLEX III - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 10 decision: EXISTING_MODULE module: mitochondrial_complex_iii - id: FBgg0001845 symbol: MCV-T name: MITOCHONDRIAL COMPLEX V - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 17 decision: EXISTING_MODULE module: mitochondrial_complex_v - id: FBgg0001846 symbol: PSM-V name: PROTEASOME 26S COMPLEX VARIANTS source: gene_group n_members: 50 decision: NEW_MODULE module: dmel_proteasome - id: FBgg0001847 symbol: MCIV-U name: MITOCHONDRIAL COMPLEX IV source: gene_group n_members: 15 decision: EXISTING_MODULE module: mitochondrial_complex_iv - id: FBgg0001848 symbol: MCII-T name: MITOCHONDRIAL COMPLEX II (SUCCINATE DEHYDROGENASE) - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 4 decision: EXISTING_MODULE module: mitochondrial_complex_ii - id: FBgg0001849 symbol: MCV-U name: MITOCHONDRIAL COMPLEX V source: gene_group n_members: 16 decision: EXISTING_MODULE module: mitochondrial_complex_v - id: FBgg0001850 symbol: MCIII-U name: MITOCHONDRIAL COMPLEX III source: gene_group n_members: 10 decision: EXISTING_MODULE module: mitochondrial_complex_iii - id: FBgg0001851 symbol: SEC61TC name: SEC61 TRANSLOCON COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_sec61_translocon - id: FBgg0001852 symbol: SEC61T-T name: SEC61 TRANSLOCON - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_sec61_translocon inherited_from: SEC61TC - id: FBgg0001854 symbol: PHTF name: PHTF PUTATIVE SEVEN TRANSMEMBRANE DOMAIN ION CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CHEMOR - id: FBgg0001855 symbol: GRL name: GUSTATORY RECEPTOR-LIKE source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CHEMOR - id: FBgg0001856 symbol: GPCR-A-U name: UNCLASSIFIED CLASS A GPCRs source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-A - id: FBgg0001857 symbol: ASLC name: ATYPICAL SOLUTE CARRIERS source: gene_group n_members: 18 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001858 symbol: ARSB name: CITRATE TRANSPORTER-LIKE DOMAIN/ARSB-LIKE TRANSPORTERS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: UIC - id: FBgg0001859 symbol: UIC name: ION CHANNELS OF UNCLASSIFIED CONDUCTANCE source: gene_group n_members: 75 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0001860 symbol: PRC1-VAR name: POLYCOMB REPRESSIVE COMPLEX 1, SU(Z)2 VARIANT source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0001861 symbol: PRC2-JJ name: POLYCOMB REPRESSIVE COMPLEX 2, JARID2-JING VARIANT source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0001864 symbol: OGDH-C name: OXOGLUTARATE DEHYDROGENASE COMPLEX - OGDH1 VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: tca_cycle inherited_from: OGDH-CV - id: FBgg0001865 symbol: USP46-C name: USP46 DEUBIQUITINASE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_usp46_deubiquitinase_complex - id: FBgg0001866 symbol: CKM name: CKM COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_mediator_complex inherited_from: MEDC - id: FBgg0001867 symbol: MEDC name: MEDIATOR COMPLEXES source: gene_group n_members: 30 decision: NEW_MODULE module: dmel_mediator_complex - id: FBgg0001868 symbol: MIS12B name: KINETOCHORE MIS12 COMPLEX - NF1B VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_kmn_network inherited_from: KMN - id: FBgg0001869 symbol: MIS12A name: KINETOCHORE MIS12 COMPLEX - NF1A VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_kmn_network inherited_from: KMN - id: FBgg0001870 symbol: NDC80C name: NDC80 KINETOCHORE COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_kmn_network inherited_from: KMN - id: FBgg0001871 symbol: KMN name: KMN PROTEIN NETWORK SUPERCOMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_kmn_network - id: FBgg0001872 symbol: KNL1 name: KNL1 SUBUNIT source: gene_group n_members: 1 decision: SUBSUMED module: dmel_kmn_network inherited_from: KMN - id: FBgg0001873 symbol: EPS8 name: EPS8 GENE FAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001874 symbol: OGDH-CV name: OXOGLUTARATE DEHYDROGENASE COMPLEX VARIANTS source: gene_group n_members: 4 decision: EXISTING_MODULE module: tca_cycle - id: FBgg0001875 symbol: OGDH-T name: OXOGLUTARATE DEHYDROGENASE COMPLEX - OGDH2 VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: tca_cycle inherited_from: OGDH-CV - id: FBgg0001877 symbol: ICCRC name: INTRACELLULAR CALCIUM-RELEASE CHANNEL SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0001879 symbol: TMBIM name: TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING PROTEIN FAMILY source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0001880 symbol: VGIC name: VOLTAGE-GATED ION CHANNEL SUBUNITS source: gene_group n_members: 35 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: GIC - id: FBgg0001881 symbol: GIC name: ION CHANNELS BY GATING MECHANISM source: gene_group n_members: 302 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IC - id: FBgg0001882 symbol: CNNM name: CNNM-TYPE Mg[2+]-EFFLUX TRANSPORTER SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: ICC - id: FBgg0001883 symbol: CLAC name: CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0001884 symbol: MA63 name: TMEM63 MECHANICALLY ACTIVATED ION CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001885 symbol: TMCL name: TRANSMEMBRANE CHANNEL-LIKE FAMILY SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001886 symbol: NALCN name: SODIUM LEAK CHANNEL COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_nalcn_channel_complex - id: FBgg0001887 symbol: TRIC name: TRIMERIC INTRACELLULAR CATION CHANNEL SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KCN - id: FBgg0001888 symbol: CACN-SU name: VOLTAGE-GATED CALCIUM CHANNEL SUBUNITS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0001889 symbol: CACN-AC name: VOLTAGE-GATED CALCIUM CHANNEL ACCESSORY SUBUNITS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CACN-SU - id: FBgg0001890 symbol: MCUNI-T name: MITOCHONDRIAL CALCIUM UNIPORTER COMPLEX - CG4704 VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_mitochondrial_calcium_uniporter inherited_from: MCU-CPXS - id: FBgg0001891 symbol: MCU-CPXS name: MITOCHONDRIAL CALCIUM UNIPORTER COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_mitochondrial_calcium_uniporter - id: FBgg0001892 symbol: PTMT name: PRIMARY ACTIVE TRANSPORTERS source: gene_group n_members: 227 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMT - id: FBgg0001893 symbol: PPTMT name: P-P-BOND-HYDROLYSIS-DRIVEN TRANSPORTERS source: gene_group n_members: 133 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PTMT - id: FBgg0001894 symbol: ROTTMT name: ROTARY ATPASE TRANSPORTERS source: gene_group n_members: 60 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PPTMT - id: FBgg0001895 symbol: P-TMT name: P-TYPE ATPASE TRANSPORTERS source: gene_group n_members: 21 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PPTMT - id: FBgg0001896 symbol: FLIP-P4 name: P4-ATPASE PHOSPHOLIPID FLIPPASE SUBUNITS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: P-TMT - id: FBgg0001897 symbol: FLIP-P4-A name: P4-ATPASE PHOSPHOLIPID FLIPPASE ACCESSORY SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: FLIP-P4 - id: FBgg0001898 symbol: TOMM-C name: TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEXES source: gene_group n_members: 9 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0001899 symbol: TOMM-T name: TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEX - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 7 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TOMM-C - id: FBgg0001900 symbol: TOMM name: TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE COMPLEX source: gene_group n_members: 7 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TOMM-C - id: FBgg0001901 symbol: VNN name: VANINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0001902 symbol: SEC-PF name: GENERAL SECRETORY PATHWAY COMPLEXES source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_sec61_translocon - id: FBgg0001903 symbol: TIM17RF name: TIM17-RELATED FAMILY source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001904 symbol: MPT name: MITOCHONDRIAL PROTEIN IMPORT COMPLEXES source: gene_group n_members: 32 decision: NEW_MODULE module: dmel_mitochondrial_protein_import - id: FBgg0001905 symbol: TIMM22 name: TIM22 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE COMPLEX source: gene_group n_members: 6 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0001907 symbol: TIMM23 name: TIM23 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE COMPLEX SUBUNITS source: gene_group n_members: 18 decision: NEW_MODULE module: dmel_mitochondrial_protein_import - id: FBgg0001908 symbol: PAM name: PRESEQUENCE TRANSLOCASE-ASSOCIATED MOTOR SUBUNITS source: gene_group n_members: 6 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23 - id: FBgg0001909 symbol: TIMM23C name: TIM23 TRANSLOCASE CORE SUBUNITS source: gene_group n_members: 7 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23 - id: FBgg0001910 symbol: TIMM17 name: TIM17 FAMILY TRANSLOCONS source: gene_group n_members: 6 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23C - id: FBgg0001911 symbol: TIM23F name: TIM23 FAMILY TRANSLOCONS source: gene_group n_members: 1 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23C - id: FBgg0001912 symbol: TIM23SSU name: TIM23 ACCESSORY SUBUNITS source: gene_group n_members: 2 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23 - id: FBgg0001913 symbol: TIM50F name: TIM50 PRESEQUENCE RECEPTOR SUBUNITS source: gene_group n_members: 3 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMM23 - id: FBgg0001914 symbol: TIM22F name: TIM22 FAMILY TRANSLOCONS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: TIM17RF - id: FBgg0001915 symbol: TMEM135 name: TMEM135 FAMILY source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: TIM17RF - id: FBgg0001916 symbol: TIMMDC1 name: TIMMDC1 FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: TIM17RF - id: FBgg0001917 symbol: NDUFA11 name: NDUFA11 FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: TIM17RF - id: FBgg0001918 symbol: ROMO1 name: ROMO1 FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001919 symbol: LKB1C name: LKB1-STRAD-MO25 SERINE/THREONINE PROTEIN KINASE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_lkb1_strad_mo25_complex - id: FBgg0001920 symbol: SEC62-63 name: SEC62/SEC63 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_sec61_translocon - id: FBgg0001921 symbol: SEC-T name: ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_sec61_translocon - id: FBgg0001922 symbol: SEC-TRAP name: SEC61 TRANSLOCON-ASSOCIATED PROTEINS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_sec61_translocon - id: FBgg0001923 symbol: MRN name: MRN COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_mrn_complex - id: FBgg0001924 symbol: MKDC name: MITOCHONDRIAL ALPHA-KETOACID DEHYDROGENASE COMPLEXES source: gene_group n_members: 15 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0001925 symbol: PDC-V name: PYRUVATE DEHYDROGENASE COMPLEX VARIANTS source: gene_group n_members: 8 decision: EXISTING_MODULE module: pyruvate_metabolism - id: FBgg0001926 symbol: PDC-S name: PYRUVATE DEHYDROGENASE COMPLEX - PDHA1 VARIANT source: gene_group n_members: 7 decision: SUBSUMED module: pyruvate_metabolism inherited_from: PDC-V - id: FBgg0001927 symbol: PDC-T name: PYRUVATE DEHYDROGENASE COMPLEX - PDHA2 VARIANT source: gene_group n_members: 7 decision: SUBSUMED module: pyruvate_metabolism inherited_from: PDC-V - id: FBgg0001928 symbol: BCKDC name: BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE COMPLEX source: gene_group n_members: 4 decision: EXISTING_MODULE module: branched_chain_amino_acid_catabolism - id: FBgg0001929 symbol: OXA1 name: YIDC/ALB3/OXA1 MEMBRANE PROTEIN INSERTASE FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SINGLE_GENE reason: Single-gene group; a module needs at least two parts. - id: FBgg0001930 symbol: SCRAM name: PHOSPHOLIPID SCRAMBLASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0001931 symbol: OXRED-TMT name: OXIDOREDUCTION-DRIVEN TRANSMEMBRANE TRANSPORTERS source: gene_group n_members: 94 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PTMT - id: FBgg0001932 symbol: PTMI name: PROTEIN TRANSLOCONS source: gene_group n_members: 12 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMT - id: FBgg0001933 symbol: TMCAP name: CHANNELS AND PORES source: gene_group n_members: 400 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: TMT - id: FBgg0001934 symbol: TMT name: TRANSMEMBRANE TRANSPORTERS source: gene_group n_members: 1044 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. - id: FBgg0001935 symbol: MECHO name: MECHANOSENSITIVE ION CHANNEL SUBUNITS source: gene_group n_members: 15 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: GIC - id: FBgg0001936 symbol: MECH-PPK name: MECHANOSENSITIVE PICKPOCKET ION CHANNELS source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: MECHO - id: FBgg0001937 symbol: MECH-TRP name: MECHANOSENSITIVE TRANSIENT RECEPTOR POTENTIAL ION CHANNELS source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: MECHO - id: FBgg0001938 symbol: RNA-EXOC name: CYTOPLASMIC EXOSOME COMPLEX source: gene_group n_members: 9 decision: SUBSUMED module: dmel_rna_exosome inherited_from: RNAEXO - id: FBgg0001939 symbol: RNAEXO name: RNA EXOSOME COMPLEXES source: gene_group n_members: 10 decision: NEW_MODULE module: dmel_rna_exosome - id: FBgg0001940 symbol: AUG name: AUGMIN COMPLEX source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_augmin_complex - id: FBgg0001941 symbol: CGAS-STING-P name: POSITIVE REGULATORS OF CGAS-STING SIGNALING PATHWAY source: signaling_pathway n_members: 1 decision: REGULATOR_SET reason: Genetic regulators of the pathway; context for the pathway module, not mechanistic parts. - id: FBgg0001942 symbol: MICOS name: MITOCHONDRIAL CONTACT SITE AND CRISTAE ORGANIZING SYSTEM COMPLEXES source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_micos_complex - id: FBgg0001943 symbol: MICOS-C10B name: MICOS COMPLEX - MIC10B VARIANT source: gene_group n_members: 5 decision: SUBSUMED module: dmel_micos_complex inherited_from: MICOS - id: FBgg0001944 symbol: MICOS-C10C name: MICOS COMPLEX - MIC10C TESTIS-SPECIFIC VARIANT source: gene_group n_members: 5 decision: SUBSUMED module: dmel_micos_complex inherited_from: MICOS - id: FBgg0001945 symbol: MICOS-C10A name: MICOS COMPLEX - MIC10A TESTIS-SPECIFIC VARIANT source: gene_group n_members: 5 decision: SUBSUMED module: dmel_micos_complex inherited_from: MICOS - id: FBgg0001947 symbol: MPV17L name: MPV17/PMP22 PUTATIVE MITOCHONDRIAL CHANNEL FAMILY source: gene_group n_members: 9 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PMP22-MPV17 - id: FBgg0001948 symbol: LGIC-U name: UNCLASSIFIED LIGAND-GATED ION CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: LGIC - id: FBgg0001949 symbol: PCC name: POLYCYSTIN CATION CHANNEL FAMILY source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001950 symbol: VDAC name: MITOCHONDRIAL PORINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: VGIC - id: FBgg0001951 symbol: PEX-RT name: PEROXISOMAL UBIQUITIN LIGASE RETROTRANSLOCON COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: peroxisome-lifecycle inherited_from: PEXTSC - id: FBgg0001952 symbol: PEX-DTM name: PEROXISOMAL DOCKING AND TRANSLOCATION MODULE source: gene_group n_members: 2 decision: SUBSUMED module: peroxisome-lifecycle inherited_from: PEXTSC - id: FBgg0001953 symbol: PTS name: PEROXISOMAL TARGETING SYSTEM COMPONENTS source: gene_group n_members: 12 decision: EXISTING_MODULE module: peroxisome-lifecycle - id: FBgg0001955 symbol: PEX-MEC name: PEROXISOMAL MEMBRANE EXTRACTION COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: peroxisome-lifecycle inherited_from: PEXTSC - id: FBgg0001957 symbol: ER-SECIN name: ENDOPLASMIC RETICULUM SECRETORY AND TRANSMEMBRANE PROTEIN INSERTION SYSTEM COMPLEXES source: gene_group n_members: 17 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0001958 symbol: CAACT name: CALCIUM-ACTIVATED ION CHANNELS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGIC - id: FBgg0001959 symbol: SLC25-MP name: SLC25 FAMILY OF MITOCHONDRIAL AND PEROXISOMAL TRANSPORTERS source: gene_group n_members: 49 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0001960 symbol: SLC25-P name: SLC25 FAMILY OF PEROXISOMAL TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC25-MP - id: FBgg0001961 symbol: OADHC name: OXOADIPATE DEHYDROGENASE COMPLEX source: gene_group n_members: 3 decision: EXISTING_MODULE module: lysine_catabolism - id: FBgg0001962 symbol: OADH name: OXOADIPATE DEHYDROGENASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAOD - id: FBgg0001963 symbol: PICTS name: PANORAMIX-INDUCED CO-TRANSCRIPTIONAL SILENCING COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_pirna_nuclear_complexes - id: FBgg0001964 symbol: MCIA name: MITOCHONDRIAL COMPLEX I INTERMEDIATE ASSEMBLY COMPLEX source: gene_group n_members: 5 decision: EXISTING_MODULE module: complex_i_assembly_factors - id: FBgg0001965 symbol: PMP22-MPV17 name: MPV17/PMP22 CHANNEL FAMILY source: gene_group n_members: 10 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: NSCC - id: FBgg0001966 symbol: PXMP2L name: MPV17/PMP22 PUTATIVE PEROXISOMAL CHANNEL FAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PMP22-MPV17 - id: FBgg0001967 symbol: OXRCHCHNAD-U name: UNCLASSIFIED CH-CH OXIDOREDUCTASES, NAD OR NADP AS ACCEPTOR source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCHNAD - id: FBgg0001968 symbol: ABCB-HTH name: ABCB ATP-BINDING CASSETTE TRANSPORTER HMT-1 SUBFAMILY - HALF TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: ABCB - id: FBgg0001969 symbol: HHTC name: HIPHOP-HOAP TELOMERE-CAPPING COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_terminin_telomere_capping - id: FBgg0001970 symbol: MTV name: MTV COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_terminin_telomere_capping - id: FBgg0001971 symbol: TRFC name: ERF1-ERF3 TRANSLATION TERMINATION COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_erf1_erf3_termination_complex - id: FBgg0001972 symbol: NXF name: NXF1-NXT1 MRNA NUCLEAR EXPORT FACTOR COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mrna_nuclear_export - id: FBgg0001973 symbol: OSTB name: OLIGOSACCHARYL TRANSFERASE B COMPLEX source: gene_group n_members: 8 decision: SUBSUMED module: oligosaccharyltransferase_complex inherited_from: OST-C - id: FBgg0001974 symbol: OST-C name: OLIGOSACCHARYLTRANSFERASE COMPLEXES source: gene_group n_members: 11 decision: EXISTING_MODULE module: oligosaccharyltransferase_complex - id: FBgg0001975 symbol: MT-REP name: MITOCHONDRIAL DNA REPLISOME source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_mitochondrial_dna_replisome - id: FBgg0001976 symbol: HK-CAM name: HBS-KIRRE CELL ADHESION COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_irm_myoblast_adhesion inherited_from: IRM-CAM - id: FBgg0001977 symbol: RS-CAM name: RST-SNS CELL ADHESION COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_irm_myoblast_adhesion inherited_from: IRM-CAM - id: FBgg0001978 symbol: HR-CAM name: HBS-RST CELL ADHESION COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_irm_myoblast_adhesion inherited_from: IRM-CAM - id: FBgg0001979 symbol: SK-CAM name: SNS-KIRRE CELL ADHESION COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_irm_myoblast_adhesion inherited_from: IRM-CAM - id: FBgg0001980 symbol: IRM-CAM name: IRM ADHESION COMPLEXES source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_irm_myoblast_adhesion - id: FBgg0001981 symbol: ECUP name: EIF4E-CUP COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_eif4e_cup_complex - id: FBgg0001982 symbol: DRM-R name: DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF VARIANT source: gene_group n_members: 10 decision: SUBSUMED module: dmel_muvb_complexes inherited_from: MUVB-C - id: FBgg0001983 symbol: DRM-R2 name: DREAM TRANSCRIPTIONAL REPRESSOR COMPLEX, RBF2 VARIANT source: gene_group n_members: 9 decision: SUBSUMED module: dmel_muvb_complexes inherited_from: MUVB-C - id: FBgg0001984 symbol: MUVB-C name: MUVB COMPLEXES source: gene_group n_members: 14 decision: NEW_MODULE module: dmel_muvb_complexes - id: FBgg0001985 symbol: TMAC name: TESTIS-SPECIFIC MEIOTIC ARREST COMPLEX source: gene_group n_members: 6 decision: SUBSUMED module: dmel_muvb_complexes inherited_from: MUVB-C - id: FBgg0001986 symbol: MMC name: MYB-MUVB TRANSCRIPTIONAL ACTIVATION COMPLEX source: gene_group n_members: 6 decision: SUBSUMED module: dmel_muvb_complexes inherited_from: MUVB-C - id: FBgg0001987 symbol: MUVB name: MUVB CORE SUBUNITS source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_muvb_complexes - id: FBgg0001988 symbol: RIC name: RAPS-INSC COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_raps_insc_complex - id: FBgg0001989 symbol: NIAUF name: MITOCHONDRIAL 2FE-2S ASSEMBLY COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_iron_sulfur_cluster_assembly - id: FBgg0001990 symbol: APKC name: ATYPICAL PROTEIN KINASE C SUBFAMILY source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PKC - id: FBgg0001991 symbol: CPKC name: CLASSICAL PROTEIN KINASE C SUBFAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PKC - id: FBgg0001992 symbol: NPKC name: NOVEL PROTEIN KINASE C SUBFAMILY source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PKC - id: FBgg0001993 symbol: ADHNAD name: ALCOHOL DEHYDROGENASES (NAD-DEPENDENT) source: gene_group n_members: 11 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0001994 symbol: TDRD3-TOP3B name: TDRD3-TOP3B TYPE IA TOPOISOMERASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_tdrd3_top3b_complex - id: FBgg0001995 symbol: IDH-UC name: ISOCITRATE DEHYDROGENASE COMPLEX source: gene_group n_members: 3 decision: EXISTING_MODULE module: tca_cycle - id: FBgg0001996 symbol: DPH1-DPH2 name: DPH1-DPH2 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_diphthamide_dph1_dph2_complex - id: FBgg0001997 symbol: DHDDSC name: DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: dolichyl_phosphate_biosynthesis - id: FBgg0001998 symbol: EXT1-EXT2 name: EXT1-EXT2 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_glycosaminoglycan_biosynthesis - id: FBgg0001999 symbol: GCLC name: GLUTAMATE-CYSTEINE LIGASE COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: glutathione_biosynthesis - id: FBgg0002000 symbol: GATCAB name: GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_glutamyl_trna_amidotransferase - id: FBgg0002001 symbol: GCC name: GLYCINE CLEAVAGE COMPLEX source: gene_group n_members: 4 decision: EXISTING_MODULE module: glycine_cleavage_system - id: FBgg0002002 symbol: PDSS name: PRENYL DIPHOSPHATE SYNTHASE COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: ubiquinone_biosynthesis - id: FBgg0002003 symbol: MCCC name: METHYLCROTONOYL-COA CARBOXYLASE COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: leucine_catabolism - id: FBgg0002004 symbol: MTP name: MITOCHONDRIAL TRIFUNCTIONAL PROTEIN COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: fatty_acid_beta_oxidation - id: FBgg0002005 symbol: MPTS name: MOLYBDOPTERIN SYNTHASE COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: molybdenum_cofactor_biosynthesis - id: FBgg0002006 symbol: RNRC name: RIBONUCLEOTIDE REDUCTASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_ribonucleotide_reductase - id: FBgg0002007 symbol: SPTC name: SERINE C-PALMITOYLTRANSFERASE COMPLEX source: gene_group n_members: 5 decision: EXISTING_MODULE module: sphingolipid_de_novo_synthesis - id: FBgg0002008 symbol: TGTC name: TRNA-GUANINE TRANSGLYCOSYLASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_trna_guanine_transglycosylase - id: FBgg0002009 symbol: UNAGTC name: UDP-N-ACETYLGLUCOSAMINE TRANSFERASE COMPLEX source: gene_group n_members: 3 decision: EXISTING_MODULE module: n_glycan_llo_assembly_cytoplasmic - id: FBgg0002010 symbol: SUCLAC name: SUCCINATE-COA LIGASE (ADP/ATP) COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: tca_cycle - id: FBgg0002011 symbol: SUCLGC name: SUCCINATE-COA LIGASE (GDP/GTP) COMPLEX source: gene_group n_members: 2 decision: EXISTING_MODULE module: tca_cycle - id: FBgg0002012 symbol: GBBH name: GAMMA-BUTYROBETAINE HYDROXYLASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRPMO2O - id: FBgg0002013 symbol: MDRS name: MITOCHONDRIAL DISULFIDE RELAY SYSTEM source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_mitochondrial_protein_import - id: FBgg0002014 symbol: TIMS name: MITOCHONDRIAL INTERMEMBRANE SPACE TIM CHAPERONE COMPLEXES source: gene_group n_members: 6 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0002015 symbol: TIM813-U name: TIM8-TIM13 COMPLEX - CG34132 VARIANT source: gene_group n_members: 2 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMS - id: FBgg0002016 symbol: TIM813-T name: TIM8-TIM13 COMPLEX - TIM13 VARIANT (TESTIS) source: gene_group n_members: 2 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMS - id: FBgg0002017 symbol: CLPXP name: MITOCHONDRIAL CLPXP COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mitochondrial_clpxp - id: FBgg0002018 symbol: MXR name: MXR METABOTROPIC GLUTAMATE-LIKE RECEPTORS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Receptor or ligand classification; pathway membership is captured by the signaling pathway modules. inherited_from: GPCR-C - id: FBgg0002019 symbol: SM-KCA name: SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAKC - id: FBgg0002020 symbol: CAKC name: CALCIUM-ACTIVATED POTASSIUM CHANNELS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAACT - id: FBgg0002021 symbol: BKCA name: CALCIUM AND VOLTAGE-ACTIVATED LARGE CONDUCTANCE POTASSIUM CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KV - id: FBgg0002022 symbol: BKNA name: SODIUM AND VOLTAGE-ACTIVATED LARGE CONDUCTANCE POTASSIUM CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: KV - id: FBgg0002023 symbol: IGIC name: INORGANIC ION-GATED ION CHANNELS source: gene_group n_members: 20 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: GIC - id: FBgg0002024 symbol: NAAIC name: SODIUM-ACTIVATED ION CHANNELS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: IGIC - id: FBgg0002025 symbol: PSCHT name: PSEUDO-CHITINASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. inherited_from: GH18 - id: FBgg0002026 symbol: GDPFUC name: DE NOVO GDP-FUCOSE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_gdp_fucose_biosynthesis - id: FBgg0002028 symbol: PPS name: PENTOSE PHOSPHATE SHUNT source: metabolic_pathway n_members: 7 decision: EXISTING_MODULE module: pentose_phosphate_pathway - id: FBgg0002030 symbol: INT name: INTEGRATOR COMPLEX source: gene_group n_members: 15 decision: NEW_MODULE module: dmel_integrator_complex - id: FBgg0002031 symbol: INTAC name: INTEGRATOR-PP2A COMPLEX source: gene_group n_members: 17 decision: NEW_MODULE module: dmel_integrator_complex - id: FBgg0002032 symbol: CLC-EX name: CLC ENDOLYSOSOMAL CHLORIDE/PROTON ANTIPORTERS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: SLC - id: FBgg0002033 symbol: MCI-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX I ASSEMBLY FACTORS source: gene_group n_members: 21 decision: EXISTING_MODULE module: complex_i_assembly_factors - id: FBgg0002034 symbol: MCIII-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX III ASSEMBLY FACTORS source: gene_group n_members: 9 decision: NEW_MODULE module: dmel_respiratory_complex_assembly_factors - id: FBgg0002035 symbol: MC-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX ASSEMBLY FACTORS source: gene_group n_members: 61 decision: UMBRELLA reason: Subunit-type or assembly-factor category; children are triaged individually. - id: FBgg0002036 symbol: MCR-AF name: MITOCHONDRIAL RESPIRASOME ASSEMBLY FACTORS source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_respiratory_complex_assembly_factors - id: FBgg0002037 symbol: MCII-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX II ASSEMBLY FACTORS source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_respiratory_complex_assembly_factors - id: FBgg0002038 symbol: MCIV-AF name: MITOCHONDRIAL RESPIRATORY CHAIN COMPLEX IV ASSEMBLY FACTORS source: gene_group n_members: 24 decision: EXISTING_MODULE module: complex_iv_assembly_factors - id: FBgg0002039 symbol: MCV-AF name: MITOCHONDRIAL PROTON-TRANSPORTING ATP SYNTHASE COMPLEX ASSEMBLY FACTORS source: gene_group n_members: 6 decision: NEW_MODULE module: dmel_respiratory_complex_assembly_factors - id: FBgg0002040 symbol: OXP-AF name: MITOCHONDRIAL OXPHOS COMPLEX ASSEMBLY FACTORS source: gene_group n_members: 66 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002041 symbol: GLYCB name: GLYCOGEN BIOSYNTHESIS source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: glycogen_biosynthesis - id: FBgg0002043 symbol: GLYCO name: GLYCOLYSIS source: metabolic_pathway n_members: 12 decision: EXISTING_MODULE module: emp_glycolysis - id: FBgg0002044 symbol: TREHB name: TREHALOSE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: NEW_MODULE module: dmel_trehalose_metabolism - id: FBgg0002045 symbol: CHIYBI name: CHITIN BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: NEW_MODULE module: dmel_chitin_metabolism - id: FBgg0002046 symbol: CHITCA name: CHITIN CATABOLISM source: metabolic_pathway n_members: 12 decision: NEW_MODULE module: dmel_chitin_metabolism - id: FBgg0002047 symbol: GLUCO name: GLUCONEOGENESIS source: metabolic_pathway n_members: 15 decision: EXISTING_MODULE module: gluconeogenesis - id: FBgg0002048 symbol: GLYCC name: GLYCOGEN CATABOLISM source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: glycogenolysis - id: FBgg0002049 symbol: UDPGAB name: UDP-GLUCURONATE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_udp_glucuronate_xylose_biosynthesis - id: FBgg0002050 symbol: UDPGLAB name: UDP-N-ACETYLGLUCOSAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 9 decision: EXISTING_MODULE module: hexosamine_biosynthesis - id: FBgg0002051 symbol: FRUCBIO name: FRUCTOSE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_polyol_pathway - id: FBgg0002052 symbol: TREHC name: TREHALOSE CATABOLISM source: metabolic_pathway n_members: 2 decision: NEW_MODULE module: dmel_trehalose_metabolism - id: FBgg0002053 symbol: CMPNEB name: CMP-N-ACETYLNEURAMINATE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: sialic_acid_metabolism - id: FBgg0002054 symbol: UDPXYLB name: UDP-XYLOSE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_udp_glucuronate_xylose_biosynthesis - id: FBgg0002055 symbol: MANGPG name: GDP-MANNOSE BIOSYNTHESIS source: metabolic_pathway n_members: 7 decision: NEW_MODULE module: dmel_gdp_mannose_biosynthesis - id: FBgg0002056 symbol: GALCA name: GALACTOSE CATABOLISM source: metabolic_pathway n_members: 6 decision: EXISTING_MODULE module: galactose_leloir_pathway - id: FBgg0002057 symbol: PHLP name: PHOSDUCIN-LIKE PROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002058 symbol: PAPSB name: 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE (PAPS) BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: paps_sulfate_activation - id: FBgg0002059 symbol: MALSH name: MALATE-ASPARTATE SHUTTLE source: metabolic_pathway n_members: 6 decision: EXISTING_MODULE module: malate_aspartate_shuttle - id: FBgg0002060 symbol: GACSB name: CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS source: metabolic_pathway n_members: 8 decision: NEW_MODULE module: dmel_glycosaminoglycan_biosynthesis - id: FBgg0002061 symbol: GACSC name: CHONDROITIN SULFATE PROTEOGLYCAN CATABOLISM source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: keratan_chondroitin_sulfate_lysosomal_degradation - id: FBgg0002062 symbol: GAHSB name: HEPARAN SULFATE PROTEOGLYCAN BIOSYNTHESIS source: metabolic_pathway n_members: 13 decision: NEW_MODULE module: dmel_glycosaminoglycan_biosynthesis - id: FBgg0002063 symbol: GLPSH name: GLYCEROPHOSPHATE SHUTTLE source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: glycerol_phosphate_shuttle - id: FBgg0002064 symbol: GAHSC name: HEPARAN SULFATE PROTEOGLYCAN CATABOLISM source: metabolic_pathway n_members: 7 decision: EXISTING_MODULE module: heparan_sulfate_lysosomal_degradation - id: FBgg0002065 symbol: MAGT name: MAGNESIUM TRANSPORTING P-ATPASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: P-ATPASE - id: FBgg0002066 symbol: AMPK-C name: AMPK COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_ampk_complex - id: FBgg0002067 symbol: SREBP-SCAP name: SREBP-SCAP COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_srebp_scap_complex - id: FBgg0002068 symbol: SEPT-C12P name: SEP1-SEP2-PNUT SEPTIN COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_septin_complexes inherited_from: SEPT-C - id: FBgg0002069 symbol: SEPT-C45P name: SEP4-SEP5-PNUT SEPTIN COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_septin_complexes inherited_from: SEPT-C - id: FBgg0002070 symbol: SEPT-C name: SEPTIN COMPLEXES source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_septin_complexes - id: FBgg0002072 symbol: ISA name: MITOCHONDRIAL 4FE-4S ASSEMBLY COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_iron_sulfur_cluster_assembly - id: FBgg0002073 symbol: NADSAL name: NAD(+) BIOSYNTHESIS VIA THE SALVAGE PATHWAY source: metabolic_pathway n_members: 10 decision: EXISTING_MODULE module: nad_biosynthesis_salvage - id: FBgg0002074 symbol: CIA-SCAF name: CYTOSOLIC 4FE-4S ASSEMBLY SCAFFOLD COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_iron_sulfur_cluster_assembly - id: FBgg0002075 symbol: CTC name: CYTOSOLIC 4FE-4S ASSEMBLY TARGETING COMPLEX source: gene_group n_members: 4 decision: NEW_MODULE module: dmel_iron_sulfur_cluster_assembly - id: FBgg0002076 symbol: OXRFES name: IRON-SULFUR PROTEIN OXIDOREDUCTASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXR - id: FBgg0002077 symbol: OXRCHCHQ name: CH-CH OXIDOREDUCTASES, QUINONE AS ACCEPTOR source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCH - id: FBgg0002078 symbol: DHODH name: DIHYDROOROTATE DEHYDROGENASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRCHCHQ - id: FBgg0002079 symbol: ECH name: ENOYL-COA HYDRATASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: HLYA - id: FBgg0002080 symbol: CCLYA-U name: UNCLASSIFIED CARBON-CARBON LYASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CCLYA - id: FBgg0002081 symbol: POLYA-U name: UNCLASSIFIED PHOSPHORUS-OXYGEN LYASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: POLYA - id: FBgg0002082 symbol: ALDH name: ALDEHYDE DEHYDROGENASES (NAD-DEPENDENT) source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAONAD - id: FBgg0002083 symbol: P5CDH name: PYRROLINE-5-CARBOXYLATE DEHYDROGENASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRAONAD - id: FBgg0002084 symbol: CBR name: CARBONYL REDUCTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AKR - id: FBgg0002085 symbol: VLCOCR name: VERY-LONG-CHAIN 3-OXOACYL-COA REDUCTASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0002086 symbol: GRHPR name: GLYOXYLATE AND HYDROXYPYRUVATE REDUCTASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0002087 symbol: COAT name: COA-TRANSFERASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TTSG - id: FBgg0002088 symbol: ATHT name: ALKYLTHIOLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: TTSG - id: FBgg0002089 symbol: NADK name: NAD+ KINASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: KIN - id: FBgg0002090 symbol: GLYAT name: GLYCINE N-ACYLTRANSFERASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NAAAT - id: FBgg0002091 symbol: AAGT-U name: UNCLASSIFIED AMINOACYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAGT - id: FBgg0002092 symbol: GT92 name: GT92 FAMILY GALACTOSYLTRANSFERASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GALT - id: FBgg0002093 symbol: GLCNACT-U name: UNCLASSIFIED N-ACETYLGLUCOSAMINYLTRANSFERASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GLCNACT - id: FBgg0002094 symbol: PAF1C-T name: RNA POLYMERASE-ASSOCIATED FACTOR 1 COMPLEX - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_rnapii_elongation_complexes - id: FBgg0002095 symbol: MTX name: METAXINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002096 symbol: AGA name: ASPARTYLGLUCOSAMINIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0002097 symbol: AMPA name: ADENOSINE MONOPHOSPHORAMIDASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHLA - id: FBgg0002098 symbol: PUDP name: PSEUDOURIDINE 5'-PHOSPHATASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: PHOSASE - id: FBgg0002099 symbol: NAG4S name: N-ACETYLGALACTOSAMINE-4-SULFATASES source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: SEHYD - id: FBgg0002100 symbol: CNHCAN name: CARBON-NITROGEN HYDROLASES OF CYCLIC AMIDINES source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CNHNP - id: FBgg0002101 symbol: COADP name: COENZYME A DIPHOSPHATASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: AAH - id: FBgg0002102 symbol: POGLY name: PROTEIN O-GLYCOSYLATION source: metabolic_pathway n_members: 46 decision: NEW_MODULE module: dmel_protein_o_glycosylation - id: FBgg0002103 symbol: TCACY name: TRICARBOXYLIC ACID (TCA) CYCLE source: metabolic_pathway n_members: 17 decision: EXISTING_MODULE module: tca_cycle - id: FBgg0002104 symbol: POGLCN name: PROTEIN O-GlcNAcYLATION source: metabolic_pathway n_members: 3 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002105 symbol: POFUC name: PROTEIN O-FUCOSYLATION source: metabolic_pathway n_members: 3 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002106 symbol: POMAN name: PROTEIN O-MANNOSYLATION source: metabolic_pathway n_members: 6 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002107 symbol: POGLC name: PROTEIN O-GLUCOSYLATION source: metabolic_pathway n_members: 3 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002108 symbol: POGAL name: PROTEIN O-GALACTOSYLATION source: metabolic_pathway n_members: 2 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002109 symbol: POGALN name: PROTEIN O-GalNAcYLATION source: metabolic_pathway n_members: 12 decision: SUBSUMED module: dmel_protein_o_glycosylation inherited_from: POGLY - id: FBgg0002110 symbol: MTERF name: MTERF FAMILY source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002111 symbol: NGH-U name: UNCLASSIFIED N-GLYCOSYL HYDROLASES source: gene_group n_members: 6 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NGH - id: FBgg0002112 symbol: FUCD name: FUCOSE DEHYDROGENASES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: OXRNAD - id: FBgg0002113 symbol: PYRCOA name: PYRUVATE DECARBOXYLATION TO ACETYL-COA source: metabolic_pathway n_members: 10 decision: EXISTING_MODULE module: pyruvate_metabolism - id: FBgg0002114 symbol: METWD name: METTL1-WUHO TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mettl1_wuho_methyltransferase - id: FBgg0002115 symbol: DDK name: DBF4-DEPENDENT CDC7 KINASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_replication_origin_licensing_activation - id: FBgg0002116 symbol: CCC-911 name: CHECKPOINT CLAMP COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_9_1_1_checkpoint_clamp - id: FBgg0002117 symbol: ATR-ATRIP name: ATR-ATRIP DNA DAMAGE-SENSING KINASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_atr_atrip_complex - id: FBgg0002118 symbol: CLNK-C12 name: CYCLIN K-CDK12 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_cyclin_k_cdk12_complex - id: FBgg0002119 symbol: PGASN name: PROTEIN N-GLYCOSYLATION source: metabolic_pathway n_members: 43 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002120 symbol: DOLMAN name: DOLICHYL-PHOSPHATE MANNOSE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: dolichol_phosphate_sugar_donor_supply - id: FBgg0002121 symbol: PGLLO name: DOLICHOL-LINKED OLIGOSACCHARIDE BIOSYNTHESIS source: metabolic_pathway n_members: 26 decision: EXISTING_MODULE module: n_glycan_llo_assembly_cytoplasmic - id: FBgg0002122 symbol: PGERT name: ENDOPLASMIC RETICULUM N-GLYCAN TRIMMING source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_n_glycan_processing - id: FBgg0002123 symbol: PGGOT name: GOLGI N-GLYCAN TRIMMING source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_n_glycan_processing - id: FBgg0002124 symbol: PGGOD name: GOLGI N-GLYCAN DIVERSIFICATION source: metabolic_pathway n_members: 9 decision: NEW_MODULE module: dmel_n_glycan_processing - id: FBgg0002125 symbol: FESCA name: IRON-SULFUR CLUSTER ASSEMBLY source: metabolic_pathway n_members: 20 decision: NEW_MODULE module: dmel_iron_sulfur_cluster_assembly - id: FBgg0002126 symbol: MOBCOB name: Mo-MOLYBDOPTERIN COFACTOR BIOSYNTHESIS source: metabolic_pathway n_members: 7 decision: EXISTING_MODULE module: molybdenum_cofactor_biosynthesis - id: FBgg0002127 symbol: UBIQS name: UBIQUINONE BIOSYNTHESIS source: metabolic_pathway n_members: 14 decision: EXISTING_MODULE module: ubiquinone_biosynthesis - id: FBgg0002128 symbol: HEMBS name: HEME BIOSYNTHESIS source: metabolic_pathway n_members: 11 decision: EXISTING_MODULE module: heme_biosynthesis - id: FBgg0002129 symbol: RPS-T name: CYTOPLASMIC SMALL RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 37 decision: SUBSUMED module: dmel_cytoplasmic_ribosome inherited_from: CRP - id: FBgg0002130 symbol: RPL-T name: CYTOPLASMIC LARGE RIBOSOMAL SUBUNIT - TESTIS-SPECIFIC VARIANT source: gene_group n_members: 51 decision: SUBSUMED module: dmel_cytoplasmic_ribosome inherited_from: CRP - id: FBgg0002131 symbol: GLU2ABII name: GLUCOSIDASE II COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_n_glycan_processing - id: FBgg0002132 symbol: MPC2BC name: MITOCHONDRIAL PYRUVATE CARRIER COMPLEX - Mpc2b VARIANT source: gene_group n_members: 2 decision: EXISTING_MODULE module: pyruvate_metabolism - id: FBgg0002133 symbol: MPC2AC name: MITOCHONDRIAL PYRUVATE CARRIER COMPLEX - Mpc2a VARIANT source: gene_group n_members: 2 decision: EXISTING_MODULE module: pyruvate_metabolism - id: FBgg0002134 symbol: CARMET name: CARBOHYDRATE METABOLISM source: metabolic_pathway n_members: 80 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002135 symbol: COCAVIT name: COFACTORS, CARRIERS AND VITAMIN METABOLISM source: metabolic_pathway n_members: 70 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002136 symbol: ENERM name: ENERGY METABOLISM source: metabolic_pathway n_members: 122 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002137 symbol: GLYCJM name: GLYCOCONJUGATE METABOLISM source: metabolic_pathway n_members: 137 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002138 symbol: NTSUB name: NUCLEOTIDE-SUGAR BIOSYNTHESIS source: metabolic_pathway n_members: 30 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002139 symbol: OXPATP name: OXIDATIVE PHOSPHORYLATION source: metabolic_pathway n_members: 89 decision: EXISTING_MODULE module: oxphos - id: FBgg0002140 symbol: MPP name: MITOCHONDRIAL PROCESSING PEPTIDASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mitochondrial_protein_import - id: FBgg0002141 symbol: IMP name: MITOCHONDRIAL INNER MEMBRANE PEPTIDASE COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mitochondrial_protein_import - id: FBgg0002142 symbol: GBP3MC name: GTPBP3-MTO1 COMPLEX source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_gtpbp3_mto1_complex - id: FBgg0002143 symbol: MITDEG name: MITOCHONDRIAL DEGRADOSOME source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_mitochondrial_degradosome - id: FBgg0002144 symbol: PTWP name: PTW-PP1 PHOSPHATASE COMPLEXES source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_ptw_pp1_complexes - id: FBgg0002145 symbol: PTW-FLW name: PTW-PP1 COMPLEX FLW VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_ptw_pp1_complexes inherited_from: PTWP - id: FBgg0002146 symbol: PTW-PP1-13C name: PTW-PP1 COMPLEX PP1-13C VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_ptw_pp1_complexes inherited_from: PTWP - id: FBgg0002147 symbol: PTW-PP1-87B name: PTW-PP1 COMPLEX PP1-87B VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_ptw_pp1_complexes inherited_from: PTWP - id: FBgg0002148 symbol: PTW-PP1ALPHA-96A name: PTW-PP1 COMPLEX PP1ALPHA-96A VARIANT source: gene_group n_members: 4 decision: SUBSUMED module: dmel_ptw_pp1_complexes inherited_from: PTWP - id: FBgg0002149 symbol: GLUCEB name: GLUCOSYLCERAMIDE BIOSYNTHESIS source: metabolic_pathway n_members: 9 decision: EXISTING_MODULE module: glycosphingolipid_biosynthesis - id: FBgg0002150 symbol: GPIANB name: GPI-ANCHOR PROTEIN BIOSYNTHESIS source: metabolic_pathway n_members: 26 decision: EXISTING_MODULE module: gpi_anchor_core_glycan_assembly - id: FBgg0002151 symbol: DOLPB name: DOLICHYL PHOSPHATE BIOSYNTHESIS source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: dolichyl_phosphate_biosynthesis - id: FBgg0002152 symbol: CSLIG-U name: UNCLASSIFIED CARBON-SULFUR LIGASES source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: CSLIG - id: FBgg0002153 symbol: SVWC name: SINGLE VON WILLEBRAND FACTOR TYPE C DOMAIN PROTEINS source: gene_group n_members: 14 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002154 symbol: SPEC name: SPECTRINS source: gene_group n_members: 8 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002155 symbol: DNMK name: DEOXYNUCLEOSIDE MONOPHOSPHATE KINASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: NUBCK - id: FBgg0002156 symbol: HDP name: HOST DEFENSE PEPTIDES source: gene_group n_members: 52 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. - id: FBgg0002157 symbol: DCNS name: DROSOCINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0002158 symbol: DPT name: DIPTERICINS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0002159 symbol: DEFN name: DEFENSINS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0002160 symbol: METK name: METCHNIKOWINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: AMP - id: FBgg0002161 symbol: HDP-U name: UNCLASSIFIED HOST DEFENSE PEPTIDES source: gene_group n_members: 5 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0002162 symbol: LYA-U name: UNCLASSIFIED LYASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: LYA - id: FBgg0002163 symbol: TIM23-SORT name: TIM23 MITOCHONDRIAL IMPORT INNER MEMBRANE SORT COMPLEX source: gene_group n_members: 4 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0002164 symbol: TIM23-MOTOR name: TIM23 TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE MOTOR COMPLEX source: gene_group n_members: 9 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0002165 symbol: NEXT name: NUCLEAR EXOSOME TARGETING COMPLEX source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_rna_exosome - id: FBgg0002166 symbol: SAM-U name: SORTING AND ASSEMBLY MACHINERY COMPLEX - Mtx2 VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0002167 symbol: SAM-T name: SORTING AND ASSEMBLY MACHINERY COMPLEX - CG5662 VARIANT source: gene_group n_members: 3 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: MPT - id: FBgg0002168 symbol: TIM910 name: TIM9-TIM10 COMPLEX source: gene_group n_members: 2 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMS - id: FBgg0002169 symbol: TIM-3SU name: TIM9A-TIM10-TIM9B COMPLEX source: gene_group n_members: 3 decision: SUBSUMED module: dmel_mitochondrial_protein_import inherited_from: TIMS - id: FBgg0002170 symbol: LSERBI name: L-SERINE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: phosphorylated_serine_biosynthesis - id: FBgg0002171 symbol: GLYCLE name: GLYCINE CLEAVAGE SYSTEM source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: glycine_cleavage_system - id: FBgg0002172 symbol: LVALCA name: L-VALINE CATABOLISM source: metabolic_pathway n_members: 9 decision: EXISTING_MODULE module: branched_chain_amino_acid_catabolism - id: FBgg0002173 symbol: LCYSBI name: L-CYSTEINE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: EXISTING_MODULE module: homocysteine_metabolism - id: FBgg0002174 symbol: LILECA name: L-ISOLEUCINE CATABOLISM source: metabolic_pathway n_members: 8 decision: EXISTING_MODULE module: branched_chain_amino_acid_catabolism - id: FBgg0002175 symbol: LMETSA name: L-METHIONINE SALVAGE PATHWAY source: metabolic_pathway n_members: 5 decision: NEW_MODULE module: dmel_methionine_salvage - id: FBgg0002176 symbol: GLYBITH name: GLYCINE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_glycine_biosynthesis - id: FBgg0002177 symbol: LLEUCA name: L-LEUCINE CATABOLISM source: metabolic_pathway n_members: 10 decision: EXISTING_MODULE module: leucine_catabolism - id: FBgg0002178 symbol: LMETCY name: L-METHIONINE CYCLE source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: methionine_cycle - id: FBgg0002179 symbol: LLYSCA name: L-LYSINE CATABOLISM source: metabolic_pathway n_members: 9 decision: EXISTING_MODULE module: lysine_catabolism_saccharopine - id: FBgg0002180 symbol: PHETYRME name: L-PHENYLALANINE AND L-TYROSINE METABOLISM source: metabolic_pathway n_members: 7 decision: EXISTING_MODULE module: tyrosine_catabolism - id: FBgg0002181 symbol: LPROBI name: L-PROLINE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: proline_metabolism - id: FBgg0002182 symbol: SEL name: SELENOPROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. - id: FBgg0002183 symbol: AAMET name: AMINO ACID METABOLISM source: metabolic_pathway n_members: 72 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002184 symbol: GLUGLNM name: L-GLUTAMATE AND L-GLUTAMINE METABOLISM source: metabolic_pathway n_members: 6 decision: EXISTING_MODULE module: glutamate_glutamine_ammonia_hub - id: FBgg0002185 symbol: ASPASNM name: L-ASPARTATE AND L-ASPARAGINE METABOLISM source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_aspartate_asparagine_metabolism - id: FBgg0002186 symbol: ARGMET name: L-ARGININE METABOLISM source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_arginine_metabolism - id: FBgg0002187 symbol: LGLUBIP name: L-GLUTAMATE BIOSYNTHESIS (FROM L-PROLINE) source: metabolic_pathway n_members: 2 decision: EXISTING_MODULE module: proline_metabolism - id: FBgg0002188 symbol: ALAMET name: L-ALANINE METABOLISM source: metabolic_pathway n_members: 1 decision: NOT_A_MODULE reason_code: SINGLE_GENE reason: Single-gene group; a module needs at least two parts. - id: FBgg0002189 symbol: TRYCAT name: L-TRYPTOPHAN CATABOLISM source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_ommochrome_biosynthesis - id: FBgg0002190 symbol: smTIMS name: SMALL TIMS source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HOLD - id: FBgg0002191 symbol: PRELID name: PRELI-DOMAIN PROTEINS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002192 symbol: 4CSP name: 4-CYSTEINE SOLUBLE PROTEINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002193 symbol: MCU-CH name: MITOCHONDRIAL CALCIUM UNIPORTER CHANNEL SUBUNITS source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0002194 symbol: CRAC-CH name: CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: CAC - id: FBgg0002195 symbol: NALCN-CH name: SODIUM LEAK CHANNEL SUBUNITS source: gene_group n_members: 1 decision: NEW_MODULE module: dmel_nalcn_channel_complex - id: FBgg0002196 symbol: PEXTSC name: PEROXISOMAL TARGETING SYSTEM COMPLEXES source: gene_group n_members: 7 decision: EXISTING_MODULE module: peroxisome-lifecycle - id: FBgg0002197 symbol: S61TRAN name: SEC61 TRANSLOCONS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PTMI - id: FBgg0002198 symbol: TOM40 name: TOM40 FAMILY TRANSLOCONS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Transporter and channel classification by transport mechanism and substrate. inherited_from: PTMI - id: FBgg0002199 symbol: HSP60-II name: HEAT SHOCK PROTEIN 60 CHAPERONINS - GROUP II source: gene_group n_members: 8 decision: NEW_MODULE module: dmel_cct_chaperonin - id: FBgg0002200 symbol: DNAPOL-SU name: DNA POLYMERASE SUBUNITS source: gene_group n_members: 19 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002201 symbol: RABGEF-TLD name: RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS - TRI LONGIN DOMAIN source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Small-GTPase regulators grouped by activity (GAP or GEF) and target GTPase family. inherited_from: RABGEF - id: FBgg0002202 symbol: TRAPP-CAT name: TRAPP GUANINE NUCLEOTIDE EXCHANGE FACTOR CATALYTIC CORE SUBUNITS source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_trapp_complexes - id: FBgg0002203 symbol: RAGS name: RAG GTPASES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: RAS-SF - id: FBgg0002204 symbol: RAGGEF name: RAG GUANINE NUCLEOTIDE EXCHANGE FACTORS source: gene_group n_members: 2 decision: NEW_MODULE module: dmel_torc1_nutrient_sensing - id: FBgg0002205 symbol: NFY name: CCAAT-BINDING FACTOR COMPLEX SUBUNITS source: gene_group n_members: 3 decision: NEW_MODULE module: dmel_nf_y_complex - id: FBgg0002206 symbol: GPN name: GPN-LOOP GTPASES source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: GTPASE - id: FBgg0002207 symbol: GTF-SU name: GENERAL TRANSCRIPTION FACTORS source: gene_group n_members: 36 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002208 symbol: IBIN name: IBIN PEPTIDES source: gene_group n_members: 2 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HDP - id: FBgg0002209 symbol: TEP name: THIOESTER-CONTAINING PROTEINS source: gene_group n_members: 4 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002210 symbol: CSP name: CYTOSKELETON STRUCTURAL PROTEINS source: gene_group n_members: 25 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. - id: FBgg0002211 symbol: AADERMT name: AMINO ACID DERIVATIVE METABOLISM source: metabolic_pathway n_members: 34 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002212 symbol: NEUROME name: NEUROTRANSMITTER METABOLISM source: metabolic_pathway n_members: 28 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002213 symbol: PIGMBIO name: PIGMENT BIOSYNTHESIS source: metabolic_pathway n_members: 13 decision: NEW_MODULE module: dmel_cuticle_tanning_pigmentation - id: FBgg0002214 symbol: KETOGENS name: KETOGENESIS source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: ketogenesis - id: FBgg0002215 symbol: KETOLYS name: KETOLYSIS source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: ketone_body_oxidation - id: FBgg0002216 symbol: GLTHCATA name: GLUTHATIONE CATABOLISM source: metabolic_pathway n_members: 8 decision: EXISTING_MODULE module: glutathione_synthesis_gamma_glutamyl_cycle - id: FBgg0002217 symbol: POLYBIO name: POLYAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: polyamine_metabolism - id: FBgg0002218 symbol: BALABIO name: BETA-ALANINE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_cuticle_tanning_pigmentation - id: FBgg0002219 symbol: GLTHBIO name: GLUTHATIONE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: EXISTING_MODULE module: glutathione_biosynthesis - id: FBgg0002220 symbol: POLYCAT name: POLYAMINE CATABOLISM source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: polyamine_metabolism - id: FBgg0002221 symbol: HYPUBIO name: HYPUSINE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: NEW_MODULE module: dmel_hypusine_biosynthesis - id: FBgg0002222 symbol: TAUBIO name: TAURINE BIOSYNTHESIS source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: taurine_biosynthesis_and_transport - id: FBgg0002223 symbol: SERMELBI name: SEROTONIN AND MELATONIN BIOSYNTHESIS source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: serotonin_melatonin_biosynthesis - id: FBgg0002224 symbol: HISMET name: HISTAMINE METABOLISM source: metabolic_pathway n_members: 6 decision: NEW_MODULE module: dmel_histamine_metabolism - id: FBgg0002225 symbol: GABASH name: GABA SHUNT source: metabolic_pathway n_members: 5 decision: EXISTING_MODULE module: gaba_shunt - id: FBgg0002226 symbol: TYROCTBI name: TYRAMINE AND OCTOPAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_tyramine_octopamine_biosynthesis - id: FBgg0002227 symbol: DOPABI name: DOPAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: EXISTING_MODULE module: catecholamine_biosynthesis - id: FBgg0002228 symbol: HTSBIO name: HYDROGEN SULFIDE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: EXISTING_MODULE module: homocysteine_metabolism - id: FBgg0002229 symbol: NOSBIO name: NITRIC OXIDE BIOSYNTHESIS source: metabolic_pathway n_members: 1 decision: EXISTING_MODULE module: nitric_oxide_cgmp_signaling - id: FBgg0002230 symbol: SULOXID name: SULFIDE OXIDATION source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_sulfide_oxidation - id: FBgg0002231 symbol: MELABI name: MELANIN BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: SUBSUMED module: dmel_cuticle_tanning_pigmentation inherited_from: PIGMBIO - id: FBgg0002232 symbol: DYNADAB name: DEHYDRO-N-ACETYLDOPAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 2 decision: SUBSUMED module: dmel_cuticle_tanning_pigmentation inherited_from: PIGMBIO - id: FBgg0002233 symbol: OMMOBI name: OMMOCHROME PIGMENT BIOSYNTHESIS source: metabolic_pathway n_members: 6 decision: NEW_MODULE module: dmel_ommochrome_biosynthesis - id: FBgg0002234 symbol: DYNBADB name: DEHYDRO-N-BETA-ALANYLDOPAMINE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: SUBSUMED module: dmel_cuticle_tanning_pigmentation inherited_from: PIGMBIO - id: FBgg0002235 symbol: PGRF name: POLYCOMB GROUP RING FINGERS source: gene_group n_members: 3 decision: NOT_A_MODULE reason_code: SEQUENCE_FAMILY reason: Gene family grouped by sequence or domain homology; members do not form one complex or pathway. - id: FBgg0002236 symbol: VPRC1-1 name: BCORL-SIESTA-RING1 COMPLEX source: gene_group n_members: 7 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0002237 symbol: VPRC1-3-5 name: TAY-SIESTA-RING1 COMPLEX source: gene_group n_members: 5 decision: NEW_MODULE module: dmel_polycomb_group_complexes - id: FBgg0002238 symbol: CARLIPB name: CARDIOLIPIN BIOSYNTHESIS AND REMODELLING source: metabolic_pathway n_members: 6 decision: NEW_MODULE module: dmel_cardiolipin_biosynthesis_remodeling - id: FBgg0002239 symbol: CARSHUT name: CARNITINE SHUTTLE source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: carnitine_shuttle - id: FBgg0002240 symbol: CARNIBI name: L-CARNITINE BIOSYNTHESIS source: metabolic_pathway n_members: 4 decision: NEW_MODULE module: dmel_carnitine_biosynthesis - id: FBgg0002241 symbol: LIPMET name: LIPID METABOLISM source: metabolic_pathway n_members: 44 decision: UMBRELLA reason: Category grouping several distinct complexes or pathways; children are triaged individually. - id: FBgg0002242 symbol: CIMALSH name: CITRATE-MALATE SHUTTLE source: metabolic_pathway n_members: 3 decision: NEW_MODULE module: dmel_citrate_malate_shuttle - id: FBgg0002243 symbol: NADPHRE name: NADPH REGENERATION source: metabolic_pathway n_members: 5 decision: NEW_MODULE module: dmel_cytosolic_nadph_regeneration - id: FBgg0002244 symbol: FADREG name: FAD REGENERATION, ETF-ETFQO SYSTEM source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: electron_transfer_flavoprotein_system - id: FBgg0002245 symbol: LIPOBI name: LIPOATE BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: endogenous_protein_lipoylation - id: FBgg0002246 symbol: FADFMNB name: FMN AND FAD BIOSYNTHESIS source: metabolic_pathway n_members: 3 decision: EXISTING_MODULE module: flavin_cofactor_biosynthesis - id: FBgg0002247 symbol: MTFABIO name: FATTY ACID BIOSYNTHESIS (MITOCHONDRIA) source: metabolic_pathway n_members: 6 decision: NEW_MODULE module: dmel_mitochondrial_fatty_acid_synthesis - id: FBgg0002248 symbol: FABEOXM name: FATTY ACID BETA-OXIDATION (MITOCHONDRIA) source: metabolic_pathway n_members: 10 decision: EXISTING_MODULE module: fatty_acid_beta_oxidation - id: FBgg0002249 symbol: FABEOXP name: FATTY ACID BETA-OXIDATION (PEROXISOME) source: metabolic_pathway n_members: 13 decision: EXISTING_MODULE module: peroxisomal_beta_oxidation - id: FBgg0002250 symbol: HOLD name: HOLDASES source: gene_group n_members: 25 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. - id: FBgg0002251 symbol: ATP-PT name: ATP-DEPENDENT PROTEIN TRANSMEMBRANE TRANSPORTERS source: gene_group n_members: 1 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Enzyme classification by catalytic activity (EC-like); members do not act together. inherited_from: ATPASETT - id: FBgg0002252 symbol: PFH name: PREFOLDIN HOLDASES source: gene_group n_members: 7 decision: NOT_A_MODULE reason_code: FUNCTIONAL_CLASS reason: Proteins grouped by a broad activity class (structural proteins, chaperones, host-defence peptides, selenoproteins), not by acting together. inherited_from: HOLD