discrepancy:
- gene: C28G1.2
  text: 'The only annotation (extracellular region) is removed in the review: the protein lacks a signal
    peptide and its paralogs are intracellular serpins.'
  sources:
  - Alliance_Automated
- gene: F44E5.4
  text: Current automated text places the protein in the ER lumen, while the review describes a cytosolic
    HSP70 lacking ER targeting signals.
  sources:
  - Alliance_Automated
- gene: P91866
  text: Acyltransferase activity is removed in the review because the fragment lacks the ketoacyl synthase
    active site.
  sources:
  - Alliance_Automated
- gene: acs-1
  text: UniProt's adipocyte differentiation role is a mammalian carry-over with no worm counterpart.
  sources:
  - UniProt
- gene: akt-2
  text: WormBase says akt-2 inactivation causes constitutive dauer arrest; the review says single mutants
    have mild phenotypes and dauer arrest requires akt-1; akt-2 double loss.
  sources:
  - Alliance_Imported
- gene: anc-1
  text: The automated kinesin binding claim is marked over-annotated in the review.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: apa-2
  text: The automated GTPase activating protein binding term is removed in the review because the partner
    RME-6 is a GEF.
  sources:
  - Alliance_Automated
- gene: asna-1
  text: WormBase calls ASNA-1 a putative membrane transporter; the review describes a cytosolic GET3 ATPase
    targeting tail-anchored proteins to the ER.
  sources:
  - Alliance_Imported
- gene: atg-13
  text: The automated piecemeal microautophagy of the nucleus term is marked over-annotated in the review
    (a yeast-specific process).
  sources:
  - Alliance_Automated
  - RefSeq
- gene: atg-16.2
  text: WormBase states atg-16.2 has no obvious function; the review documents its role specifying LGG-1
    puncta sites and in embryonic aggrephagy.
  sources:
  - Alliance_Imported
  - UniProt
- gene: atg-2
  text: WormBase says atg-2 has no obvious RNAi phenotype; the review describes autophagosome formation
    and aggregate clearance defects in mutants.
  sources:
  - Alliance_Imported
  - UniProt
- gene: atg-3
  text: WormBase says no obvious phenotype; the review describes ATG-3 as essential for autophagosome
    biogenesis and aggregate clearance in embryos.
  sources:
  - Alliance_Imported
- gene: atg-5
  text: WormBase says atg-5 has no obvious function; the review describes loss of LGG-1 lipidation and
    puncta in atg-5 mutants.
  sources:
  - Alliance_Imported
- gene: bbs-1
  text: The automated patched binding and smoothened binding terms are removed in the review.
  sources:
  - Alliance_Automated
- gene: bir-1
  text: The automated egg-laying behavior and inductive cell migration processes are marked over-annotated
    in the review.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: car-1
  text: UniProt and the automated text present CAR-1 as a promoter-binding transcriptional regulator;
    the review treats CAR-1 as an LSM14 mRNA-binding protein and holds the DNA-binding annotation UNDECIDED.
  sources:
  - UniProt
  - Alliance_Automated
  - RefSeq
- gene: cat-1
  text: 'The automated dopamine:sodium and serotonin:sodium:chloride symporter terms are modified in the
    review: VMAT is a proton antiporter.'
  sources:
  - Alliance_Automated
  - RefSeq
- gene: ccep-290
  text: The automated chromatin binding term is removed in the review.
  sources:
  - Alliance_Automated
- gene: cdc-14
  text: The automated text names cytoskeleton-dependent cytokinesis and mitotic spindle midzone assembly.
    The review states cdc-14 null alleles are viable and fertile with no cytokinesis defect.
  sources:
  - Alliance_Automated
- gene: ced-4
  text: WormBase calls CED-4 a novel protein. The review and the automated text describe the Apaf-1-like
    apoptosome adaptor that activates CED-3.
  sources:
  - Alliance_Imported
- gene: ced-9
  text: The automated text lists actin filament depolymerization as a process. The review MODIFIES that
    row to positive regulation of synapse pruning.
  sources:
  - Alliance_Automated
- gene: cgt-1
  text: WormBase says cgt-1 single mutants show no obvious defects. The review reports reduced brood size
    and oocyte and embryonic cytokinesis defects in cgt-1 alone.
  sources:
  - Alliance_Imported
- gene: che-13
  text: UniProt describes transport 'in the motile cilium'. The review and the other sources place CHE-13
    in non-motile sensory cilia.
  sources:
  - UniProt
- gene: clec-67
  text: The automated text gives protein folding chaperone activity, which the review removes, and PERK-mediated
    UPR, which the review marks as over-annotated. Neither text mentions the immune role.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: clk-1
  text: The automated text omits the core ubiquinone-biosynthetic hydroxylase activity and foregrounds
    the debated nuclear transcriptional role.
  sources:
  - Alliance_Automated
- gene: daf-11
  text: RefSeq gives peptide receptor activity. The review argues DAF-11 has no known peptide ligand and
    rejects the IBA.
  sources:
  - RefSeq
- gene: daf-18
  text: The automated text names protein tyrosine phosphatase activity and not the PIP3 3-phosphatase
    activity that the review treats as the core function.
  sources:
  - Alliance_Automated
- gene: dcar-1
  text: The automated text gives neuropeptide receptor activity. The review removes it because the characterized
    ligands are HPLA and DHCA, not peptides.
  sources:
  - Alliance_Automated
- gene: dct-1
  text: UniProt and WormBase present DCT-1 as an apoptosis initiator. The review says a physiological
    apoptotic role in C. elegans has not been shown and that the protein acts mainly as a mitophagy receptor.
  sources:
  - UniProt
  - Alliance_Imported
- gene: ddb-1
  text: The automated text gives nucleic acid binding activity, which the review removes.
  sources:
  - Alliance_Automated
- gene: dpm-1
  text: All descriptions attribute Dol-P-Man synthase activity to U4PF58, a 51-residue fragment lacking
    the glycosyltransferase domain; the review REMOVEs the activity annotation and assigns it to Q9TYJ7.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: dve-1
  text: WormBase omits the mitochondrial unfolded protein response, which UniProt, the automated text
    and the review treat as the core function.
  sources:
  - Alliance_Imported
  - UniProt
- gene: dyf-2
  text: WormBase and the automated text assign DYF-2 to IFT complex B; UniProt and the review identify
    it as the IFT-A subunit WDR19/IFT144 and mark the IFT-B annotation as over-annotated.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - UniProt
- gene: eat-4
  text: The automated text lists glutamate:sodium symporter activity; the review REMOVEs it because EAT-4/VGLUT
    is driven by the vesicular proton gradient.
  sources:
  - Alliance_Automated
- gene: egl-1
  text: The automated text describes EGL-1 through actin depolymerization and antibacterial defense and
    never mentions apoptosis, its defining role.
  sources:
  - Alliance_Automated
- gene: elo-6
  text: WormBase says ELO-6 may be required for a normal growth rate; the review states that elo-6 knockdown
    causes no obvious growth or developmental defect.
  sources:
  - Alliance_Imported
- gene: epg-5
  text: The automated text describes EPG-5 as a negative regulator of autophagosome assembly; the review
    MODIFYs that term and places EPG-5 in autophagosome-lysosome fusion as a RAB-7 effector.
  sources:
  - Alliance_Automated
- gene: fath-1
  text: UniProt's FUNCTION text describes myelin, epidermal barrier, sebaceous gland and hair follicle
    roles that cannot apply to C. elegans; the review cites the worm growth defect rescued by (R)-2-hydroxy
    palmitate.
  sources:
  - UniProt
- gene: fis-1
  text: The automated text and UniProt's by-similarity sentences imply a mitochondrial fission role, whereas
    WormBase and the review report that worm fis-1 is dispensable for fission and acts downstream of it.
  sources:
  - Alliance_Automated
  - UniProt
  - Alliance_Imported
- gene: fshr-1
  text: WormBase covers only the synaptic role and the automated text covers only immunity. The UniProt
    entry (unreviewed) has no FUNCTION text.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: gcy-8
  text: WormBase states GCY-18 is the primary AFD guanylyl cyclase; the gcy-8 review calls GCY-8 the principal
    individual AFD cyclase for thermotaxis, and the gcy-18 review restricts GCY-18's primacy to higher
    cultivation temperatures.
  sources:
  - Alliance_Imported
- gene: gpa-12
  text: Both automated texts lead with D5 dopamine receptor binding, which the review removes as an unsupported
    orthology transfer.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: gpr-2
  text: WormBase describes the GoLoco motif as characteristic of guanine nucleotide exchange factors;
    the review and automated text give GDP-dissociation inhibitor activity.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: gst-44
  text: WormBase says gst-44 has no obvious function; the review cites arsenite and arsenate sensitivity
    of deletion and RNAi animals.
  sources:
  - Alliance_Imported
- gene: gsto-1
  text: UniProt and the automated text assert methylarsonate reductase activity, which the review marks
    UNDECIDED for lack of worm evidence.
  sources:
  - UniProt
  - Alliance_Automated
- gene: hlh-30
  text: WormBase presents hlh-30 as an MITF ortholog with a metabolism role; UniProt and the review describe
    a TFEB ortholog driving autophagy, lysosome biogenesis and longevity.
  sources:
  - Alliance_Imported
  - UniProt
- gene: hrde-1
  text: The automated text gives RNA endonuclease activity, which the review removes because HRDE-1 lacks
    slicer catalytic residues.
  sources:
  - Alliance_Automated
- gene: hsp-12.3
  text: The automated text gives protein refolding, which the review removes because HSP-12.3 has no chaperone
    activity in vitro, as WormBase also says.
  sources:
  - Alliance_Automated
  - Alliance_Imported
- gene: hsp-12.6
  text: The automated text gives protein refolding and response to heat; WormBase and the review say HSP-12.6
    is not a chaperone in vitro and not stress-induced.
  sources:
  - Alliance_Automated
  - Alliance_Imported
- gene: hsp-70
  text: The automated text places HSP-70 in the chaperonin-containing T-complex, which the review marks
    as over-annotated.
  sources:
  - Alliance_Automated
- gene: ift-20
  text: WormBase says ift-20 has no obvious RNAi function; the review cites null mutants with vestigial
    axonemes and dye-filling, osmotic avoidance and mating defects.
  sources:
  - Alliance_Imported
- gene: ift-20
  text: UniProt places IFT-20 in the motile cilium; C. elegans IFT-20 acts in non-motile sensory cilia.
  sources:
  - UniProt
  - Alliance_Automated
- gene: ift-81
  text: UniProt says IFT-81 is required for SHH signaling and sperm flagellum elongation; C. elegans has
    no Hedgehog-cilia signaling or flagellated sperm, and the review does not include these.
  sources:
  - UniProt
- gene: lgg-1
  text: The automated text leads with predicted GABA receptor binding; the review removes that annotation
    as having no support in C. elegans.
  sources:
  - Alliance_Automated
- gene: lgg-2
  text: WormBase says lgg-2 has no obvious function. UniProt and the review describe a downstream role
    in autophagosome maturation through VPS-39/HOPS.
  sources:
  - Alliance_Imported
  - UniProt
- gene: lgg-2
  text: WormBase says lgg-2 "is not required for either dauer formation or extended lifespan"; UniProt
    says it is "Essential for dauer development and life-span extension" (PubMed:20523114). The two curated
    texts contradict each other directly.
  sources:
  - Alliance_Imported
  - UniProt
- gene: lin-65
  text: WormBase calls LIN-65 an unfamiliar protein without known function; the review describes it as
    the MET-2 H3K9 methyltransferase cofactor (ATF7IP analog).
  sources:
  - Alliance_Imported
- gene: lon-2
  text: WormBase suggests LON-2 binds DBL-1 directly; the review says direct LON-2/DBL-1 binding was not
    detected and the link is through SMOC-1.
  sources:
  - Alliance_Imported
- gene: lrx-1
  text: WormBase asserts four class A LDL receptor domains and the automated texts imply CD320 orthology;
    the review's analysis finds no canonical LDL-A domains and calls LRX-1 not an LRP family member.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: lys-1
  text: WormBase states LYS-1 expression is not promoted by DAF-16; the review describes lys-1 as a DAF-16/FOXO
    target (PMID from an RNAi screen of DAF-16 targets).
  sources:
  - Alliance_Imported
- gene: lys-7
  text: WormBase states LYS-7 hydrolyzes peptidoglycan by homology; the review says it lacks conserved
    catalytic residues and marks lysozyme activity as over-annotated.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: mec-14
  text: WormBase and the automated text relate MEC-14 to Shaker/Kv beta subunits (KCNAB1); the review
    says it belongs to an L-galactose dehydrogenase-like AKR family that has no vertebrate member.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: meg-3
  text: WormBase says MEG-3 affects hypodermal development and is expressed in all somatic cells; the
    review describes it as the main P granule scaffold in the germline and treats the GEI-12/GEX-3 interaction
    as doubtful.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: met-2
  text: WormBase and the automated text attribute H3K36 methylation to MET-2; the review removes H3K36
    methyltransferase activity and describes MET-2 as an H3K9me1/me2 enzyme.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: mff-1
  text: UniProt says MFF-1 promotes DRP1 recruitment to mitochondria; the review notes that in C. elegans
    Mff is not essential for DRP-1 recruitment.
  sources:
  - UniProt
- gene: mff-2
  text: UniProt says MFF-2 promotes DRP1 recruitment to the mitochondrial surface; the review reports
    DRP-1 still associates with mitochondria in mff-1 mff-2 double mutants.
  sources:
  - UniProt
- gene: mpz-1
  text: The automated text says MPZ-1 enables GTPase activating protein binding; the review removes this
    because the partner RHGF-2 is a RhoGEF.
  sources:
  - Alliance_Automated
- gene: mut-16
  text: WormBase predicts MUT-16 acts in chromatin organization; the review describes it as the Q/N-rich
    scaffold that nucleates perinuclear Mutator foci for siRNA amplification.
  sources:
  - Alliance_Imported
- gene: ndx-2
  text: WormBase says ndx-2 RNAi has no obvious abnormalities; the review reports increased sensitivity
    to methyl viologen and menadione.
  sources:
  - Alliance_Imported
- gene: ndx-4
  text: WormBase calls NDX-4 homodimeric; the review and the UniProt SUBUNIT note (PMID:11937063) say
    it is a monomer.
  sources:
  - Alliance_Imported
- gene: nhr-60
  text: The automated text calls NHR-60 orthologous to human RXRA/RXRB/RXRG; WormBase and the review classify
    it as a nematode-specific supplementary nuclear receptor of the HNF4 lineage.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: nipi-3
  text: WormBase describes nipi-3 as encoding a kinase; the review describes a Tribbles pseudokinase lacking
    key catalytic residues.
  sources:
  - Alliance_Imported
- gene: nlp-29
  text: UniProt states sleep is induced 'through the neuropeptide receptor nlp-29'; the review identifies
    the receptor as the neuronal GPCR NPR-12.
  sources:
  - UniProt
- gene: nuc-1
  text: WormBase says NUC-1 acts in apoptotic cells prior to engulfment; the review states corpse DNA
    degradation depends on engulfment and that action inside dying cells is debated.
  sources:
  - Alliance_Imported
- gene: odr-1
  text: The automated text states predicted peptide receptor activity; the review marks this as over-annotated,
    noting no ligand for ODR-1 is known.
  sources:
  - Alliance_Automated
- gene: osm-1
  text: UniProt says OSM-1 is required for transport in the 'motile cilium'; the review states all C.
    elegans cilia are non-motile sensory cilia.
  sources:
  - UniProt
- gene: osm-11
  text: WormBase text omits the Notch co-ligand role that UniProt, the automated text and the review treat
    as core.
  sources:
  - Alliance_Imported
- gene: pef-1
  text: WormBase says pef-1 has no known mutant phenotype; the review cites thermotaxis, salt chemotaxis,
    CO2 and UV avoidance defects and cilium microtubule abnormalities.
  sources:
  - Alliance_Imported
- gene: pfd-4
  text: WormBase cites the deletion allele as gk403; the review cites pfd-4(gk430).
  sources:
  - Alliance_Imported
- gene: pfd-5
  text: The automated text describes PFD-5 by RNA polymerase assembly terms; the review keeps these as
    non-core and treats tubulin/actin delivery to CCT as the core role.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: rde-3
  text: WormBase says MUT-2's mechanistic role and expression are unknown; the review describes poly(UG)
    polymerase activity templating RRF-1 22G-RNA synthesis in Mutator foci.
  sources:
  - Alliance_Imported
- gene: rft-2
  text: The automated text lists the IRE1-mediated unfolded protein response; the review marks it as over-annotated.
  sources:
  - Alliance_Automated
- gene: rheb-1
  text: The automated text places RHEB-1 at the plasma membrane; the review reports endogenously tagged
    RHEB-1 on lysosomal membranes with DAF-15.
  sources:
  - Alliance_Automated
- gene: rps-3
  text: The automated apoptotic signalling claim is marked MARK_AS_OVER_ANNOTATED in the review.
  sources:
  - Alliance_Automated
- gene: rrf-1
  text: WormBase says RRF-1 is required for somatic 'but not germline' RNAi; the review places it also
    in germline Mutator foci acting redundantly with EGO-1.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: sdf-9
  text: WormBase calls SDF-9 a protein tyrosine phosphatase; the review describes a pseudophosphatase
    with Ser223 replacing the catalytic cysteine.
  sources:
  - Alliance_Imported
- gene: sem-5
  text: UniProt and WormBase describe SEM-5 as a negative regulator of let-23/Ras vulval signaling; the
    review describes it as the adaptor coupling LET-23 to SOS-1/LET-60.
  sources:
  - UniProt
  - Alliance_Imported
- gene: sod-2
  text: WormBase says sod-2 might promote normal lifespan; the review states loss of sod-2 does not shorten
    and can extend lifespan.
  sources:
  - Alliance_Imported
- gene: spg-7
  text: WormBase calls spg-7 the paraplegin (SPG7) ortholog; the review and the automated text identify
    it as the AFG3L2 ortholog.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: srp-2
  text: The automated text places SRP-2 in the extracellular region, but the review reports GFP-tagged
    SRP-2 is cytosolic and not secreted.
  sources:
  - Alliance_Automated
- gene: tmem-138
  text: UniProt says TMEM-138 is required for ciliogenesis, but the review says no clear in vivo requirement
    for worm TMEM-138 in cilium formation has been shown.
  sources:
  - UniProt
- gene: ttr-52
  text: 'Both automated texts list ''apoptotic process involved in development'', which the review removes:
    TTR-52 acts in corpse engulfment, not in killing.'
  sources:
  - Alliance_Automated
  - RefSeq
- gene: ubl-5
  text: The automated text says UBL-5 enables protein tag activity; the review removes this because UBL-5
    cannot be conjugated.
  sources:
  - Alliance_Automated
- gene: ugtp-1
  text: WormBase gives UDP-galactose and the automated text CMP-sialic acid as the substrate; the review
    says the physiological substrate is unknown and sialic acid is implausible in C. elegans.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: unc-13
  text: Both automated texts list positive regulation of oocyte development, which the review removes.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: unc-32
  text: The automated text lists defense response to Gram-positive bacterium, which the review removes.
  sources:
  - Alliance_Automated
- gene: unc-47
  text: The automated text names glycine but not GABA transmembrane transporter activity as the MF; the
    review adds the GABA MF as NEW and treats glycine as non-core.
  sources:
  - Alliance_Automated
- gene: unc-57
  text: 'The automated text lists necroptotic process, which the review modifies: UNC-57 contributes non-specifically
    to necrotic neurodegeneration, not necroptosis.'
  sources:
  - Alliance_Automated
- gene: unc-64
  text: The automated text names protein-folding chaperone binding as the only MF; the review marks it
    over-annotated and gives SNAP receptor activity as core.
  sources:
  - Alliance_Automated
- gene: vha-19
  text: WormBase calls VHA-19 a predicted transmembrane rotor component that carries protons; the review
    describes an accessory single-pass subunit supporting assembly.
  sources:
  - Alliance_Imported
- gene: vps-15
  text: The automated text says VPS-15 enables protein serine/threonine kinase activity; the review removes
    all kinase rows because the domain is a pseudokinase regulating VPS-34.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: wago-1
  text: The automated text gives RNA endonuclease and miRNA binding activity; the review removes the first
    (no catalytic residues) and modifies the second to siRNA binding.
  sources:
  - Alliance_Automated
- gene: wago-4
  text: Both automated texts give RNA endonuclease activity, which the review removes because WAGO-4 lacks
    the catalytic metal-binding residues.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: zen-4
  text: WormBase and both automated texts list pronuclear migration, which the review marks over-annotated.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: znfx-1
  text: RefSeq places ZNFX-1 in chromosome, nucleus and the nuclear RNA-directed RNA polymerase complex;
    the review removes these and adds Z granule and P granule.
  sources:
  - RefSeq
gap:
- gene: J7SF87
  text: No source mentions that, unlike sqrd-1, this paralog is not induced by H2S and its deletion confers
    no H2S sensitivity, leaving its physiological role unresolved.
  sources:
  - UniProt
  - Alliance_Automated
  - RefSeq
- gene: Y56A3A.16
  text: The automated text does not mention RUB-1's Rubicon-like negative regulation of autophagy and
    lifespan, which the review adds as NEW.
  sources:
  - Alliance_Automated
- gene: abu-1
  text: Neither text mentions the CED-1-dependent role in defense against Salmonella that the review adds
    as NEW.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: acr-18
  text: No source mentions the established role of ACR-18 in backward command interneurons for male mating
    reversal behaviour.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: acs-1
  text: The automated text names epithelial cell apical/basal polarity, which the review does not mention
    or evaluate.
  sources:
  - Alliance_Automated
- gene: acs-1
  text: Neither source mentions the established requirement for C15ISO/C17ISO monomethyl branched-chain
    fatty acid synthesis.
  sources:
  - UniProt
  - Alliance_Automated
- gene: aldo-1
  text: No source mentions compensatory glycolysis in complex I mutants or the HIF-1 hypoxia program covered
    in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: asd-1
  text: Neither text names SUP-12 as the cooperating partner in egl-15 exon selection or the neuronal
    unc-32 target.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: atg-2
  text: No source names EPG-6 (WIPI3/4), the direct ATG-2 binding partner described in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: bbs-1
  text: WormBase reports increased insulin, biogenic amine and neuropeptide secretion via AEX-6 and a
    fat storage role; the review does not mention these.
  sources:
  - Alliance_Imported
- gene: bbs-2
  text: WormBase's GCY-35/GCY-36 cGMP suppression of non-ciliary BBS phenotypes is not in the review.
  sources:
  - Alliance_Imported
- gene: bbs-5
  text: WormBase's increased insulin and neuropeptide secretion phenotype (AEX-6-dependent) is not mentioned
    in the review.
  sources:
  - Alliance_Imported
- gene: bbs-7
  text: WormBase's cGMP (GCY-35/GCY-36) suppression of body size and roaming phenotypes is not in the
    review.
  sources:
  - Alliance_Imported
- gene: bbs-8
  text: WormBase's increased insulin and neuropeptide secretion phenotype is not covered in the review.
  sources:
  - Alliance_Imported
- gene: bbs-9
  text: WormBase's increased insulin, DAF-7 and FLP-21 secretion phenotype is not mentioned in the review.
  sources:
  - Alliance_Imported
- gene: cct-1
  text: WormBase says CCT-1 represses SKN-1-dependent gst-4 transcription. The review does not mention
    gst-4 or SKN-1.
  sources:
  - Alliance_Imported
- gene: cct-2
  text: None of the sources mention the oocyte RNP condensate phenotype or the lifespan and polyQ effects
    of cct-2 overexpression that the review describes.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: cct-4
  text: None of the sources mention the germline nuclear CCT-4 that binds HIM-3/HTP-1/HTP-3 and whose
    P382S allele suppresses HORMAD axis defects.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: cct-8
  text: None of the sources mention the review's finding that CCT-8 limits TRiC assembly and that its
    overexpression suppresses polyQ/Htt aggregation and extends lifespan.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: ced-13
  text: Neither source mentions the review's non-apoptotic role of CED-13 in the longevity and protective
    response of isp-1 and nuo-6 respiratory mutants.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: cep-1
  text: Neither the WormBase nor the automated text names the egl-1 and ced-13 BH3-only targets that UniProt
    and the review treat as the core output.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: cpx-1
  text: 'Neither source mentions the review''s dual role of CPX-1: clamping tonic release and promoting
    evoked synchronous release.'
  sources:
  - UniProt
  - Alliance_Automated
- gene: csr-1
  text: Neither source mentions CSR-1's protection of germline transcripts from piRNA silencing, which
    is a core function in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: daf-15
  text: RefSeq lists regulation of autophagosome assembly. The daf-15 review does not discuss autophagy.
  sources:
  - RefSeq
- gene: daf-16
  text: Neither automated text mentions lifespan determination, the best-known DAF-16 role and a core
    function in the review.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: daf-19
  text: The automated text does not mention ciliogenesis, the core DAF-19 role in the review.
  sources:
  - Alliance_Automated
- gene: daf-28
  text: WormBase says the phosphatase IDA-1 is required for DAF-28 function. The review does not mention
    IDA-1.
  sources:
  - Alliance_Imported
- gene: daf-7
  text: The automated text does not mention dauer regulation, the principal DAF-7 role.
  sources:
  - Alliance_Automated
- gene: ddb-1
  text: WormBase says CUL-4/DDB-1 regulates LET-23/EGFR signalling in vulval precursor cells. The review
    does not mention this.
  sources:
  - Alliance_Imported
- gene: deps-1
  text: The automated text gives no function at all, although the review accepts regulatory ncRNA-mediated
    gene silencing and adds P granule assembly.
  sources:
  - Alliance_Automated
- gene: dpy-23
  text: UniProt's Q neuroblast migration role is not mentioned in the review, which only refers to HSN,
    V5 and polarity in passing.
  sources:
  - UniProt
- gene: dve-1
  text: WormBase claims dve-1 interacts with EGF/RAS pathway components and is required for vulval signalling;
    the review does not mention vulval development or RAS.
  sources:
  - Alliance_Imported
- gene: dyf-1
  text: WormBase's placement of DYF-1 downstream of BBS-8 is not mentioned in the review.
  sources:
  - Alliance_Imported
- gene: dyf-11
  text: WormBase reports a physical interaction with the transition-fiber protein DYF-19/FBF1; the review
    does not mention DYF-19.
  sources:
  - Alliance_Imported
- gene: dyf-2
  text: WormBase reports that dyf-2 mutants are long-lived and resist heat stress and starvation; the
    review does not mention lifespan.
  sources:
  - Alliance_Imported
- gene: egl-1
  text: WormBase's claims that EGL-1 induces WAH-1/AIF release and is transcriptionally repressed by TRA-1
    in HSNs are not mentioned in the review.
  sources:
  - Alliance_Imported
- gene: ego-1
  text: Neither text mentions 22G-RNA synthesis or the CSR-1 pathway, which the review treats as the main
    output of EGO-1.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: eif-2alpha
  text: The automated text does not mention eIF2alpha phosphorylation in the integrated stress response,
    which the review adds as a core role.
  sources:
  - Alliance_Automated
- gene: elo-5
  text: None of the texts mention that ELO-5's C15ISO product supplies the d17iso sphingoid base, which
    the review gives as the reason for the L1 arrest.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: epg-6
  text: UniProt's role in autophagic degradation of rRNA and ribosomal proteins for nucleotide homeostasis
    (PMID:30102152) is not mentioned in the review.
  sources:
  - UniProt
- gene: fndc-1
  text: Neither text mentions hypoxia-reoxygenation-induced mitophagy in muscle, the second context in
    the review.
  sources:
  - UniProt
  - Alliance_Automated
- gene: ftt-2
  text: WormBase omits DAF-16 sequestration, the core function in the review.
  sources:
  - Alliance_Imported
- gene: gck-1
  text: WormBase does not mention the CCM-3/STRIPAK role in excretory canal tube extension, a core function
    in the review.
  sources:
  - Alliance_Imported
- gene: gcy-18
  text: WormBase states gcy-18 is DAF-16-regulated and that RNAi extends lifespan; the review does not
    mention lifespan.
  sources:
  - Alliance_Imported
- gene: gcy-23
  text: WormBase reports lifespan extension after gcy-23 RNAi; the review does not mention lifespan.
  sources:
  - Alliance_Imported
- gene: gcy-31
  text: UniProt's possible role in embryogenesis is not mentioned in the review, which describes only
    BAG O2-downshift sensing.
  sources:
  - UniProt
- gene: gcy-35
  text: WormBase's gustatory plasticity role and AHR-1-dependent URX expression are not mentioned in the
    review.
  sources:
  - Alliance_Imported
- gene: glh-1
  text: UniProt's claim that GLH-1 protects somatic cells from excess apoptosis (PMID:27650246) is not
    mentioned in the review.
  sources:
  - UniProt
- gene: glh-4
  text: UniProt says glh-4 may protect somatic cells from excessive apoptosis (PubMed:27650246); the review
    does not mention apoptosis.
  sources:
  - UniProt
- gene: glo-1
  text: WormBase says glo-1 is required during embryogenesis for normal body morphogenesis; the review
    does not cover a morphogenesis role.
  sources:
  - Alliance_Imported
- gene: glp-1
  text: UniProt says glp-1 plays a negative role in lifespan (three PMIDs); the review does not mention
    lifespan.
  sources:
  - UniProt
- gene: gpr-2
  text: WormBase says gpr-2 functions in germ-line development; the review covers only the early embryo.
  sources:
  - Alliance_Imported
- gene: gsk-3
  text: WormBase names a Wnt role in anteroposterior axon guidance; the review does not mention axon guidance.
  sources:
  - Alliance_Imported
- gene: gsk-3
  text: UniProt says gsk-3 is required for normal lifespan and LiCl-induced lifespan extension; the review
    does not cover lifespan.
  sources:
  - UniProt
- gene: gst-4
  text: The WormBase sperm guidance and prostaglandin D synthase claim is not assessed in the review beyond
    a suggested question. It needs a literature check.
  sources:
  - Alliance_Imported
- gene: hsf-1
  text: UniProt says hsf-1 plays a role in egg-laying (PubMed:15611166); the review does not mention egg-laying.
  sources:
  - UniProt
- gene: hsp-4
  text: UniProt's role in embryonic ER sheet dynamics (PubMed:15716356) and WormBase's Cry5B pore-forming
    toxin induction are not mentioned in the review.
  sources:
  - UniProt
  - Alliance_Imported
- gene: hsp-90
  text: UniProt says HSP-90 controls oocyte prophase/metaphase progression through wee-1.3 (PubMed:16466390);
    the review does not mention wee-1.3.
  sources:
  - UniProt
- gene: ire-1
  text: UniProt says ire-1 plays a role in nuclear retention of unspliced mRNAs (PubMed:23149939); the
    review does not mention it.
  sources:
  - UniProt
- gene: irg-1
  text: WormBase reports pmk-1-dependent induction by cadmium; the review does not mention cadmium.
  sources:
  - Alliance_Imported
- gene: kap-1
  text: WormBase says kap-1 expression in AWB neurons is positively regulated by FKH-2; the review does
    not mention FKH-2.
  sources:
  - Alliance_Imported
- gene: lag-2
  text: WormBase gives VPC expression and its regulation by LET-23 and SUR-2, which the review description
    omits.
  sources:
  - Alliance_Imported
- gene: let-60
  text: WormBase lists phenotypes (male spicule development, sex myoblast migration, chemotaxis, muscle
    membrane extension) that appear nowhere in the let-60 review.
  sources:
  - Alliance_Imported
- gene: lin-12
  text: UniProt names octanol avoidance and basement membrane mobility during tissue remodeling; the lin-12
    review does not cover either.
  sources:
  - UniProt
- gene: lin-45
  text: UniProt says LIN-45 positively regulates lifespan upstream of MEK-2 and MPK-1; the lin-45 review
    does not mention lifespan.
  sources:
  - UniProt
- gene: lis-1
  text: WormBase lists actin cytoskeleton integrity as a lis-1 role; the review does not mention actin.
  sources:
  - Alliance_Imported
- gene: lys-1
  text: WormBase names DBL-1, TIR-1 and NSY-1 as promoting LYS-1 expression and P. aeruginosa induction;
    the lys-1 review does not mention these regulators.
  sources:
  - Alliance_Imported
- gene: mec-14
  text: WormBase says MEC-14 likely regulates the MEC-4/MEC-10 channel; the review leaves its mechanism
    unknown and does not assess that claim.
  sources:
  - Alliance_Imported
- gene: meg-1
  text: WormBase says meg-1 expression in the proximal germline is positively regulated by MPK-1; the
    review does not mention this.
  sources:
  - Alliance_Imported
- gene: mek-2
  text: UniProt names pachytene progression, fluid homeostasis and lifespan, and WormBase names cell migration
    and olfaction; none of these appear in the mek-2 review.
  sources:
  - UniProt
  - Alliance_Imported
- gene: mks-1
  text: WormBase reports that mks-1 RNAi suppresses the egg-laying defect of egl-9 mutants and a foraging
    role with NPH-4; the mks-1 review covers neither.
  sources:
  - Alliance_Imported
- gene: mks-3
  text: WormBase says MKS-3 is required for normal cilium length and mentions sheath-socket connection
    defects; the mks-3 review does not cover either.
  sources:
  - Alliance_Imported
- gene: mpk-1
  text: The review description is much shorter than both curated texts and omits the germline roles (pachytene
    progression, NOS-3 and TRA-1 regulation) that its annotations cover.
  sources:
  - UniProt
  - Alliance_Imported
- gene: mpz-1
  text: WormBase mentions possible NPR-1 and ZC84.4 binding and uORF translational control; the mpz-1
    review does not cover these.
  sources:
  - Alliance_Imported
- gene: nlp-29
  text: WormBase mentions RAB-1 and the R53.4 ATP synthase subunit as nlp-29 regulators; the review's
    regulatory summary does not name them.
  sources:
  - Alliance_Imported
- gene: nphp-1
  text: UniProt's dendrite-extension role in phasmid neurons (PMID:34115759) is not mentioned in the review
    description or core functions.
  sources:
  - UniProt
- gene: nphp-4
  text: Neither text mentions the redundant NPHP/MKS module gating role that the review treats as core.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: nprl-3
  text: No source mentions the C. elegans genetic evidence (suppression of mmBCFA/glucosylceramide L1
    arrest) that the review cites.
  sources:
  - UniProt
  - Alliance_Automated
- gene: nsf-1
  text: Neither text mentions cis-SNARE complex disassembly or the NSF-1L uterine anchor cell fusion requirement
    that the review treats as core.
  sources:
  - UniProt
  - Alliance_Automated
- gene: nud-2
  text: No source mentions the HCP-1/HCP-2-dependent kinetochore dynein role that the review treats as
    a core function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: osm-1
  text: WormBase's ivermectin-resistance link with avr-14 is not covered in the review.
  sources:
  - Alliance_Imported
- gene: osm-3
  text: No source mentions OSM-3 autoinhibition and activation by IFT particles described in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: osm-5
  text: WormBase lists male mating and lifespan defects; the review does not discuss them.
  sources:
  - Alliance_Imported
- gene: pdha-1
  text: No source mentions the RNAi PDH-deficiency phenotypes (raised lactate/pyruvate, UPRmt, sterility)
    or PDHK-2/PDP-1 regulation covered in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: pdr-1
  text: No source mentions PINK-1/PDR-1 mitophagy, the review's central role.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: pek-1
  text: No source mentions the redundancy with ire-1/xbp-1 and atf-6 for larval viability or the ASI dauer-entry
    role in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: pfd-2
  text: No source mentions the R2TP/prefoldin-like link or the daf-2 lifespan effect noted in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: pfd-6
  text: No source mentions PFD-6 binding DAF-16 and UXT or its requirement for daf-2 lifespan extension,
    covered in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: phb-1
  text: No source mentions the context-dependent effects on lifespan (shortening in wild type, extension
    in daf-2 and dietary restriction) covered in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: pink-1
  text: No source names PDR-1 or ubiquitin Ser65 phosphorylation, the core PINK-1 mechanism in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: pkd-2
  text: WormBase names EGL-44/EGL-46 as regulators of pkd-2 expression in HOB; the review does not mention
    them.
  sources:
  - Alliance_Imported
- gene: prg-1
  text: Neither text mentions the secondary 22G-RNA/WAGO amplification or the mortal germline phenotype
    that the review treats as central.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: rab-11.1
  text: WormBase says RAB-11.1 is needed for peripheral positioning of nuclei in the syncytial germline;
    the review does not mention it.
  sources:
  - Alliance_Imported
- gene: rab-11.1
  text: UniProt's plasma membrane repair after pore-forming toxin exposure (PMID:21320697) is not discussed
    in the review.
  sources:
  - UniProt
- gene: rab-3
  text: No source mentions the GTP-dependent UNC-10/RIM interaction that recruits vesicles to the presynaptic
    density, the review's core mechanism.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: rab-5
  text: Neither text names the RME-6/RABX-5 GEFs, the TBC-2 GAP or the RAB-5 to RAB-7 conversion via SAND-1
    in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: rde-2
  text: Neither text describes RDE-2 bridging MUT-7 to MUT-16, the adaptor role the review treats as core.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: rho-1
  text: WormBase names neurite outgrowth as a rho-1 role; the review does not mention it.
  sources:
  - Alliance_Imported
- gene: ric-4
  text: The UNC-86/MEC-3 regulation of ric-4 expression in WormBase is not covered by the review.
  sources:
  - Alliance_Imported
- gene: rimb-1
  text: No source mentions RIMB-1 positioning UNC-2 calcium channels redundantly with UNC-10/RIM, the
    core function in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: rps-23
  text: WormBase names a vulval morphogenesis requirement that the review does not mention.
  sources:
  - Alliance_Imported
- gene: sbp-1
  text: UniProt names a role in the response to simulated microgravity with MDT-15; the review does not
    mention microgravity.
  sources:
  - UniProt
- gene: sec-16A.1
  text: WormBase reports colocalization with mitochondrial COX1; the review does not mention mitochondria.
  sources:
  - Alliance_Imported
- gene: sek-1
  text: UniProt's pqn-41-dependent linker cell death role is not mentioned in the review.
  sources:
  - UniProt
- gene: sel-12
  text: WormBase's SPR-2/SET regulation of sel-12 is not covered in the review.
  sources:
  - Alliance_Imported
- gene: sem-5
  text: UniProt's role in nAChR (LEV-1) synaptic levels and nicotine sensitivity is not covered by the
    review.
  sources:
  - UniProt
- gene: sid-3
  text: No source mentions the Orsay virus entry requirement or STA-1 antiviral gene repression covered
    in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: skn-1
  text: WormBase gives detailed embryonic and postembryonic expression (P1 descendants, ASI neurons, stress-enhanced
    intestinal nuclei) that the review description leaves out.
  sources:
  - Alliance_Imported
- gene: sma-2
  text: WormBase's reproductive aging role for the Sma/Mab pathway is not covered in the review.
  sources:
  - Alliance_Imported
- gene: sma-3
  text: WormBase's LIN-31 interaction and reproductive aging role are not covered in the review.
  sources:
  - Alliance_Imported
- gene: sma-3
  text: No source mentions the caenacin antimicrobial peptide induction that the review lists as a core
    function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: sma-4
  text: WormBase's RNT-1/RUNX interaction and reproductive aging role are not covered in the review.
  sources:
  - Alliance_Imported
- gene: sma-6
  text: WormBase's reproductive aging role is not covered in the review.
  sources:
  - Alliance_Imported
- gene: sma-9
  text: UniProt's ROS production and mitochondrial UPR roles are not covered in the review.
  sources:
  - UniProt
- gene: snf-12
  text: WormBase says snf-12 is essential for a neuroendocrine TGF-beta immune pathway; the review does
    not mention TGF-beta.
  sources:
  - Alliance_Imported
- gene: sos-1
  text: UniProt's nAChR (LEV-1) level and nicotine sensitivity role and G1 cell delamination role are
    not in the review.
  sources:
  - UniProt
- gene: spg-7
  text: WormBase's lifespan extension and polyQ localization phenotypes are not mentioned in the review.
  sources:
  - Alliance_Imported
- gene: sqrd-1
  text: No source mentions HIF-1 induction or the requirement for H2S survival described in the review.
  sources:
  - UniProt
  - Alliance_Automated
  - RefSeq
- gene: sta-1
  text: No source mentions STA-1 repression of antiviral genes, Orsay virus resistance or SID-3 dependence
    covered in the review.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: sysm-1
  text: Neither source mentions the role of secreted SYSM-1 in DNA damage-induced germ cell apoptosis,
    the core function in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: tir-1
  text: UniProt names linker cell death, anoxia response and arsenite-induced gcs-1 expression, none of
    which the review mentions.
  sources:
  - UniProt
- gene: ubl-5
  text: No source mentions UBL-5's spliceosome role (SART-1, PRP-38 binding), which the review lists as
    a core function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: ubl-5
  text: WormBase says UBL-5 is required for normal mitochondrial morphology and complex assembly; the
    review does not cover this.
  sources:
  - Alliance_Imported
- gene: ufd-1
  text: The automated text omits the DNA replication role (CDT-1 degradation, CMG helicase disassembly)
    that the review lists as a major function.
  sources:
  - Alliance_Automated
- gene: unc-1
  text: WormBase names the anesthetic sensitivity role and unc-24 epistasis for UNC-1 nerve ring localization;
    the review mentions neither.
  sources:
  - Alliance_Imported
- gene: unc-13
  text: WormBase lists lifespan, brood size and body size phenotypes that the review does not mention.
  sources:
  - Alliance_Imported
- gene: unc-18
  text: UniProt names ethanol-induced locomotion and the molting quiescence pathway in ALA, which the
    review does not cover.
  sources:
  - UniProt
- gene: unc-2
  text: WormBase says unc-2 is required for neuronal migrations; the review does not mention this.
  sources:
  - Alliance_Imported
- gene: unc-32
  text: WormBase describes isoform-specific splicing control by ASD-1, FOX-1 and UNC-75, which the review
    does not mention.
  sources:
  - Alliance_Imported
- gene: unc-41
  text: WormBase says UNC-41 is required for EGL-17 secretion from P6.p and for embryonic viability; the
    review mentions neither.
  sources:
  - Alliance_Imported
- gene: unc-47
  text: WormBase describes UNC-46 interdependence and UNC-30 transcriptional control, which the review
    does not mention.
  sources:
  - Alliance_Imported
- gene: unc-51
  text: Neither WormBase nor the automated text describes the autophagy initiation role (UNC-51/EPG-1/EPG-9
    complex) that the review lists as a core function.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: unc-51
  text: UniProt names P granule degradation in somatic cells, which the review does not mention.
  sources:
  - UniProt
- gene: unc-64
  text: WormBase mentions suppression of unc-64 by slo-1 mutations, which the review does not cover.
  sources:
  - Alliance_Imported
- gene: vab-1
  text: UniProt mentions a possible role in spermatheca morphogenesis, which the review does not cover.
  sources:
  - UniProt
- gene: vha-1
  text: UniProt names HRG-7 processing and secretion, and WormBase names alae formation; the review mentions
    neither.
  sources:
  - UniProt
  - Alliance_Imported
- gene: vha-13
  text: WormBase reports VHA-13 level changes in calcineurin and calreticulin mutants, which the review
    does not mention.
  sources:
  - Alliance_Imported
- gene: vps-34
  text: UniProt names roles in gut granule formation and germ stem cell proliferation that the review
    description does not cover.
  sources:
  - UniProt
- gene: wdr-23
  text: The Mn-induced CEP neuron degeneration claim in UniProt is not discussed in this entry's review.
  sources:
  - UniProt
- gene: wdr-23__P90794
  text: UniProt says WDR-23 inhibits SKN-1-mediated up-regulation of tatn-1; the review does not mention
    tatn-1.
  sources:
  - UniProt
- gene: xbp-1
  text: WormBase reports near-complete loss of myo-2 expression in xbp-1 mutants; the review does not
    mention this.
  sources:
  - Alliance_Imported
- gene: zen-4
  text: WormBase does not name the centralspindlin partner CYK-4, which the review treats as defining
    ZEN-4 function.
  sources:
  - Alliance_Imported
insight:
- gene: F44E5.4
  text: None of the sources says F44E5.4 and F44E5.5 encode the identical protein.
  sources:
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: apb-1
  text: Neither text says APB-1 is the single beta subunit shared by AP-1 and AP-2; the automated text
    mentions only AP-1 membership.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: atf-4
  text: The WormBase text still calls the gene atf-5 and treats ISR-type translational control as hypothetical.
  sources:
  - Alliance_Imported
- gene: cct-1
  text: RefSeq still carries the obsolete 'unfolded protein binding' MF that the current automated text
    has replaced.
  sources:
  - RefSeq
  - Alliance_Automated
- gene: ced-5
  text: The current Alliance automated text for ced-5 has no GO-derived function sentences, while the
    June 2026 RefSeq copy has them. The automated generation appears to have lost its GO input.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: che-2
  text: The current automated text for che-2 lost its GO-derived sentences, which the older RefSeq copy
    still has.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: daf-15
  text: The current automated text lost its GO-derived sentences, while the June 2026 RefSeq copy has
    them.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: dpy-23
  text: The automated text names necroptotic process among three highlighted processes; the review marks
    that annotation UNDECIDED and does not treat it as a function.
  sources:
  - Alliance_Automated
- gene: drp-1
  text: Automated and RefSeq texts list microtubule binding, which the review marks as over-annotated
    for DRP-1.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: dyf-1
  text: UniProt describes DYF-1 as acting in the 'motile cilium', but C. elegans sensory cilia are non-motile;
    the phrasing comes from a cross-species IFT-B statement (PMID:28479320).
  sources:
  - UniProt
- gene: dyf-13
  text: WormBase still calls DYF-13 a member of an 'unfamiliar protein family'; it is the TTC26/IFT56
    IFT-B subunit.
  sources:
  - Alliance_Imported
- gene: dyf-5
  text: WormBase calls DYF-5 a 'putative MAP kinase'; the review classes it as a MAK/RCK kinase and changes
    the MAP kinase activity annotation.
  sources:
  - Alliance_Imported
- gene: dyf-6
  text: WormBase describes DYF-6 as 'novel'; it is the IFT46 subunit of IFT-B.
  sources:
  - Alliance_Imported
- gene: dyn-1
  text: The automated text highlights necroptotic process, which the review MODIFYs; UniProt's microtubule-bundling
    statement matches annotations the review marks over-annotated.
  sources:
  - Alliance_Automated
  - UniProt
- gene: ent-1
  text: WormBase still calls ENT-1 a predicted transporter; the review cites heterologous yeast assays
    of uridine and adenosine transport.
  sources:
  - Alliance_Imported
- gene: fasn-1
  text: The WormBase text is skewed toward one regulatory paper. The review mentions the CEP-1 link under
    cep-1 but not under fasn-1.
  sources:
  - Alliance_Imported
- gene: fox-1
  text: The automated text names mRNA alternative trans-splicing; the review marks it over-annotated and
    accepts cis alternative splicing regulation instead.
  sources:
  - Alliance_Automated
- gene: fshr-1
  text: The WormBase synaptic claim led to PMID:39561202 and a NEW GO:1900075 row in the review, which
    had missed the role.
  sources:
  - Alliance_Imported
- gene: gcs-1
  text: UniProt's FUNCTION text never states that GCS-1 is glutamate-cysteine ligase; only phenotypes
    are given.
  sources:
  - UniProt
- gene: gcy-33
  text: The automated text leads with carbon monoxide sensor activity, which the review marks over-annotated;
    O2 is the physiological ligand.
  sources:
  - Alliance_Automated
- gene: gei-8
  text: WormBase still calls GEI-8 a novel protein with myb-like DNA-binding domains; the review identifies
    these as the SANT domains of the NCoR/SMRT corepressor.
  sources:
  - Alliance_Imported
- gene: gon-2
  text: No description mentions the intestinal Mg2+ uptake and Ca2+-selective I-ORCa current that the
    review treats as the core channel function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: gpx-5
  text: Both texts state glutathione peroxidase activity; the review leaves that term UNDECIDED because
    the reductant of this Cys-type GPx is unmeasured.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: gsr-1
  text: No source mentions the mitochondrial and cytosolic isoforms or the maternal-effect embryonic lethality
    that the review describes.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: gtl-1
  text: Neither text mentions dietary Mg2+ uptake or the PVD cold-sensing role, both in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: gtl-2
  text: Neither text mentions the excretory cell Mg2+ homeostasis role or epidermal wound closure described
    in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: hsp-16.1
  text: The WormBase text is the hsp-16.11 description; the review notes the two genes encode identical
    proteins.
  sources:
  - Alliance_Imported
- gene: hsp-16.48
  text: WormBase says the reporter is induced solely by stress; the review also describes constitutive
    neuronal HSP-16.48 affecting ethanol and nicotine responses.
  sources:
  - Alliance_Imported
- gene: icp-1
  text: The RefSeq text (Jun 2026) is richer than the Alliance automated text, which gives only orthology.
  sources:
  - RefSeq
  - Alliance_Automated
- gene: ift-74
  text: Neither text describes the IFT-74/81 tubulin-binding module or its regulation by DYF-5 phosphorylation,
    central in the review.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: lbp-8
  text: The automated text calls LBP-8 a long-chain fatty acid transmembrane transporter, whereas the
    review core function is soluble intracellular lipid transfer activity.
  sources:
  - Alliance_Automated
- gene: let-23
  text: The review's own description mentions only Ras/MAPK outputs, although its annotations accept ovulation
    and sleep via the PLC-gamma branch that UniProt and WormBase both name.
  sources:
  - UniProt
  - Alliance_Imported
- gene: let-363
  text: UniProt's hedge about protein versus lipid kinase activity is stale; the review accepts protein
    serine/threonine kinase activity with named TORC1 substrates.
  sources:
  - UniProt
- gene: lin-3
  text: UniProt text says 'receptor lin-23-mediated signaling cascade' where let-23 is meant.
  sources:
  - UniProt
- gene: lin-65
  text: The RefSeq text is richer than the current Alliance automated text, which has lost the chromatin
    and UPR-mt terms.
  sources:
  - RefSeq
  - Alliance_Automated
- gene: mcm-4
  text: Neither WormBase nor the automated text mentions DNA replication or the replication checkpoint,
    the review's core role.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: meg-1
  text: No source mentions the germline P-body role (Cassani and Seydoux 2022) that the review now treats
    as MEG-1's main function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: met-2
  text: No Alliance source mentions the LIN-65/ARLE-14 complex or heterochromatin anchoring that the review
    treats as central.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: mksr-1
  text: WormBase spells the gene mkrs-1 throughout; the current symbol is mksr-1.
  sources:
  - Alliance_Imported
- gene: mup-4
  text: No source mentions the STA-2 sequestration and epidermal damage-sensing role that the review includes
    as a core function.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
- gene: mut-7
  text: The automated text leads with miRNA 3'-end processing and ssDNA exonuclease activity, both marked
    over-annotated in the review.
  sources:
  - Alliance_Automated
- gene: ndx-1
  text: UniProt and the automated text present 8-oxo-(d)GDP hydrolysis as probable or predicted, though
    the review cites purified-enzyme assays.
  sources:
  - UniProt
  - Alliance_Automated
- gene: nphp-2
  text: WormBase text says nphp-2 functions together with 'nphp-1, nphp-2' - likely meant nphp-4, the
    partner named in the review.
  sources:
  - Alliance_Imported
- gene: nrde-2
  text: UniProt's nuclear-speckle/exosome function is by similarity to human NRDE2; the review notes it
    has not been tested in C. elegans.
  sources:
  - UniProt
- gene: nsy-1
  text: The current automated text dropped 'MAP kinase kinase kinase activity', the review's core MF,
    which the older RefSeq copy still states.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: nud-1
  text: Current Alliance automated text has no GO function at all, whereas the older RefSeq copy lists
    chaperone activity and pronuclear migration, both supported in the review.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: pef-1
  text: No source mentions the ciliary axoneme localization that the review identifies.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: pgl-1
  text: UniProt opens with guanyl-specific RNase activity; the review notes an RNase-dead PGL-1 Q342A
    mutant remains fertile, so this catalysis is not established as its main function.
  sources:
  - UniProt
- gene: ppgn-1
  text: The current Alliance automated text dropped the m-AAA protease and metalloendopeptidase function
    present in the older RefSeq copy and in the review.
  sources:
  - Alliance_Automated
  - RefSeq
- gene: rfth-1
  text: The UniProt caveat that flippase activity could not be confirmed in vitro is outdated; the review
    cites liposome reconstitution showing ATP-independent M5-DLO movement, while noting the essential
    role is disputed.
  sources:
  - UniProt
- gene: rhgf-2
  text: The automated 'endothelial cell migration' process is not discussed anywhere in the review and
    has no worm basis.
  sources:
  - Alliance_Automated
- gene: rme-2
  text: Automated orthology to human EGF (driven by EGF repeats) produces a misleading disease list for
    a yolk receptor.
  sources:
  - Alliance_Automated
- gene: rps-3A
  text: The WormBase text uses the old name rps-1 for this gene.
  sources:
  - Alliance_Imported
- gene: sir-2.1
  text: None of the sources notes that sir-2.1 overexpression lifespan effects are disputed, as the review
    does.
  sources:
  - UniProt
  - Alliance_Automated
- gene: snt-1
  text: The UniProt FUNCTION text is a dated by-similarity statement that never calls SNT-1 the Ca2+ sensor
    for release, which the review treats as its core function.
  sources:
  - UniProt
- gene: sqst-1
  text: Only the automated text conveys the selective autophagy receptor role; neither text notes SQST-1's
    wide use as an autophagic flux reporter.
  sources:
  - Alliance_Imported
  - Alliance_Automated
- gene: sta-1
  text: WormBase says neuronal sta-1 expression is negatively regulated by DAF-7/TGF-beta signaling; the
    review says TGF-beta signaling induces it through DAF-3. The direction should be checked against the
    source paper.
  sources:
  - Alliance_Imported
  - UniProt
- gene: tctn-1
  text: The review records TZ localization and ciliary gate function from worm data, so the 'predicted'
    qualifiers in the automated text are out of date.
  sources:
  - Alliance_Automated
- gene: tir-1
  text: WormBase predates the NADase discovery and describes TIR-1 only as a signaling adaptor; the review
    treats NADase as the primary function.
  sources:
  - Alliance_Imported
- gene: tmem-231
  text: UniProt's sonic hedgehog signaling claim comes from mammals; C. elegans lacks a canonical Hh pathway
    and the review does not use it.
  sources:
  - UniProt
- gene: tol-1
  text: The automated text lists orthology only to TRIL, CHAD and CHADL (LRR proteins), not to any Toll-like
    receptor, despite TOL-1 being the sole worm TLR.
  sources:
  - Alliance_Automated
- gene: unc-11
  text: The automated text features necroptotic process, which the review leaves UNDECIDED.
  sources:
  - Alliance_Automated
- gene: unc-13
  text: The UniProt FUNCTION text does not describe the synaptic vesicle priming role that the review
    treats as core.
  sources:
  - UniProt
- gene: unc-83
  text: The automated text places UNC-83 in the meiotic nuclear membrane microtubule tethering complex;
    the review modifies this because UNC-83 acts in somatic LINC complexes.
  sources:
  - Alliance_Automated
- gene: wdr-23
  text: This entry (S6FN32) is the D2030.9d gene model lacking both isoform N termini; the descriptions
    are gene-level and the review notes its expression and localization were never examined.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated
  - RefSeq
- gene: wdr-23__P90794
  text: None of the sources distinguishes the cytoplasmic WDR-23A (this canonical entry, mitochondrial
    outer membrane) from the nuclear WDR-23B isoform that controls SKN-1.
  sources:
  - UniProt
  - Alliance_Imported
  - Alliance_Automated