# Manual review of HTP-family `membrane` rows, 2026-10-10. Source: decisions_draft.py
- gene: ECOLI/DnaK
  row_index: 60
  reference: PMID:16858726
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'UniProt: cell inner membrane, peripheral membrane protein (ECO:0000269, PubMed:16079137).'
- gene: ECOLI/GroEL
  row_index: 60
  reference: PMID:16858726
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: UniProt places GroEL in the cytoplasm only (ECO:0000269); no protein-specific evidence of membrane association was
    found. A soluble chaperonin recovered in a complexome membrane fraction.
- gene: ECOLI/RidA
  row_index: 21
  reference: PMID:16858726
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm only; RidA is a small soluble enamine/imine deaminase with no reported membrane association.'
- gene: ECOLI/lpd
  row_index: 37
  reference: PMID:16858726
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'UniProt: cell inner membrane, peripheral membrane protein (ECO:0000269, PubMed:16079137).'
- gene: ECOLI/manX
  row_index: 26
  reference: PMID:16858726
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral inner-membrane PTS component (UniProt ECO:0000269, PubMed:2999119); the location is carried by the IDA
    plasma membrane annotation, so the generic parent is not core.
- gene: human/AAAS
  row_index: 18
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: ALADIN is a nuclear pore complex component at the nuclear envelope (UniProt ECO:0000269 nuclear pore complex and
    nuclear envelope; IDA nuclear membrane lead). Membrane association is real; the generic term adds nothing over the NPC/nuclear
    membrane annotations.
- gene: human/AARS1
  row_index: 43
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm and nucleus (ECO:0000269); a soluble cytosolic aminoacyl-tRNA synthetase with no membrane association
    on record.'
- gene: human/ABCE1
  row_index: 35
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: cytoplasmic/mitochondrial ribosome-recycling ATPase with no membrane association on record.'
- gene: human/ABCF2
  row_index: 5
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: no UniProt location; the only membrane lead is a Reactome TAS plasma membrane row, and the gene''s other
    location is cytosol.'
- gene: human/ABI3
  row_index: 41
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cytoplasm, colocalizing with PAK2 at the leading edge (ECO:0000269); ABI3 is a WAVE regulatory complex
    subunit recruited to the leading-edge membrane. Plausible peripheral association, not a core location.'
- gene: human/ABR
  row_index: 25
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: UniProt places ABR at dendritic spines, axon and synapse (by similarity); no protein-specific membrane
    evidence beyond an IBA plasma membrane lead.'
- gene: human/ACAA1
  row_index: 30
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: peroxisomal matrix thiolase (UniProt ECO:0000269).'
- gene: human/ACAP1
  row_index: 11
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: recycling endosome membrane, peripheral membrane protein (ECO:0000269, PubMed:16256741). Membrane is true;
    the specific term carries it.'
- gene: human/ACAP2
  row_index: 17
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cell membrane (ECO:0000269, PubMed:30905672) and endosome membrane, peripheral; IDA plasma membrane lead.'
- gene: human/ACBD3
  row_index: 22
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: Golgi apparatus membrane, peripheral (ECO:0000269, four PubMed citations); EXP/IDA Golgi membrane leads.'
- gene: human/ACLY
  row_index: 34
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic enzyme (UniProt ECO:0000269).'
- gene: human/ACOX1
  row_index: 30
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: peroxisome (ECO:0000269); a peroxisomal matrix acyl-CoA oxidase with no membrane association on record.'
- gene: human/ACOX3
  row_index: 22
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: peroxisomal matrix enzyme (UniProt by similarity).'
- gene: human/ACTB
  row_index: 223
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Cortical and junctional beta-actin is membrane-associated, but the generic term is not ACTB's core location (cytoskeleton).
- gene: human/ACTR1B
  row_index: 16
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: UniProt places ACTR1B on the cytoskeleton and centrosome; no protein-specific membrane evidence.'
- gene: human/AGFG2
  row_index: 6
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: No UniProt location; leads are cytoplasm and cytoplasmic vesicle only. No protein-specific evidence of membrane association
    for AGFG2.
- gene: human/AGO2
  row_index: 236
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: membrane association independently supported by membrane flotation (PMID:14749716, as recorded by the
    earlier review).'
- gene: human/AGO3
  row_index: 49
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: P-body (ECO:0000269); no membrane evidence for AGO3 (the flotation evidence cited for AGO2 does not transfer).'
- gene: human/AGO4
  row_index: 41
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: P-body (ECO:0000269); no membrane evidence for AGO4.'
- gene: human/AGPS
  row_index: 21
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: peroxisome membrane (by similarity) with ISS peroxisomal membrane lead; the generic parent is not core.'
- gene: human/AHNAK
  row_index: 45
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: plasma membrane by four IDA rows and sarcolemma IDA; peripheral, cytosol-facing protein.'
- gene: human/AIMP1
  row_index: 31
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus, cytosol, secreted (ECO:0000269); ER/Golgi by similarity only. No membrane association on record.'
- gene: human/AIMP2
  row_index: 40
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytosol (ECO:0000269) and nucleus; multisynthetase-complex scaffold with no membrane association on record.'
- gene: human/AKNA
  row_index: 17
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: centrosomal/nuclear protein.'
- gene: human/ALDH16A1
  row_index: 6
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: no location data beyond this row.'
- gene: human/ALDOA
  row_index: 34
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic/sarcomeric glycolytic enzyme; no membrane location in UniProt.'
- gene: human/ANKRD17
  row_index: 24
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm and nucleus (ECO:0000269); no membrane association on record.'
- gene: human/ANKZF1
  row_index: 21
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic, with stress-induced mitochondrial translocation.'
- gene: human/ANXA11
  row_index: 48
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: ACCEPT
  changed: false
  basis: 'Confirmed: calcium-dependent phospholipid-binding annexin whose recruitment to plasma-membrane lesions is the basis
    of its function (earlier review); no experimentally supported specific membrane term carries this.'
- gene: human/AP1G1
  row_index: 41
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: clathrin-coated vesicle membrane, peripheral (ECO:0000269); specific membrane terms (Golgi, coated vesicle
    membrane) carry the location, so the generic parent is not core.'
- gene: human/AP1S1
  row_index: 27
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: peripheral coated-vesicle membrane protein (UniProt ECO:0000269).'
- gene: human/AP3B1
  row_index: 24
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: clathrin-coated vesicle membrane, peripheral; specific coat/vesicle membrane terms carry the location.'
- gene: human/AP3D1
  row_index: 20
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'AP-3 coat subunit: UniProt Golgi membrane peripheral (by similarity) and IDA endosome membrane lead. Membrane is
    true; generic.'
- gene: human/API5
  row_index: 12
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: mainly nuclear (UniProt ECO:0000269).'
- gene: human/APOE
  row_index: 195
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: Secreted apolipoprotein on lipoprotein particles (UniProt ECO:0000269). The plasma membrane leads are Reactome TAS
    rows for APOE bound to its receptors, which does not make it a membrane constituent.
- gene: human/ARCN1
  row_index: 35
  reference: PMID:19946888
  previous_action: MODIFY
  decision: MODIFY
  changed: false
  basis: 'Confirmed: peripheral COPI coat subunit (UniProt Golgi membrane); the earlier MODIFY to a specific membrane term
    stands.'
- gene: human/ARFGEF2
  row_index: 39
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: peripheral membrane protein with IDA Golgi membrane leads.'
- gene: human/ASCC3
  row_index: 48
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: nuclear/cytosolic helicase (UniProt ECO:0000269).'
- gene: human/ATIC
  row_index: 42
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic enzyme.'
- gene: human/ATP5F1A
  row_index: 72
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral inner-membrane F1 subunit (UniProt), with IDA mitochondrial inner membrane; the specific term carries
    the location, so the generic parent is not core.
- gene: human/ATP5F1B
  row_index: 62
  reference: PMID:16210410
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral inner-membrane F1 subunit (UniProt ECO:0000269 PubMed:25168243); the specific mitochondrial membrane terms
    carry the location.
- gene: human/ATP5F1B
  row_index: 69
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral inner-membrane F1 subunit (UniProt ECO:0000269 PubMed:25168243); the specific mitochondrial membrane terms
    carry the location.
- gene: human/ATXN10
  row_index: 51
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/perinuclear and midbody protein.'
- gene: human/ATXN2
  row_index: 38
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ER/plasma-membrane association reported independently (PMID:18602463, as recorded by the earlier review).'
- gene: human/BAG6
  row_index: 60
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic/nuclear chaperone (UniProt ECO:0000269).'
- gene: human/BCL2L12
  row_index: 9
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: Bcl-2 family member lacking the C-terminal membrane anchor; nuclear location only.'
- gene: human/BIRC6
  row_index: 29
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: trans-Golgi network membrane (ECO:0000269, PubMed:18329369). Membrane is true, but not BIRC6''s core location.'
- gene: human/BRAT1
  row_index: 34
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus and cytoplasm (ECO:0000269); no membrane association on record.'
- gene: human/CAD
  row_index: 65
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm and nucleus (ECO:0000269); soluble pyrimidine-synthesis enzyme.'
- gene: human/CALCOCO2
  row_index: 33
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: autophagosome membrane (ECO:0000269, PubMed:25771791), peripheral. Membrane is true; generic.'
- gene: human/CALR
  row_index: 110
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal chaperone (UniProt ECO:0000269).'
- gene: human/CAND1
  row_index: 36
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear (UniProt ECO:0000269).'
- gene: human/CARMIL2
  row_index: 16
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Plasma membrane by EXP and IDA leads; CARMIL2 is a membrane-cytoskeleton linker (UniProt function). Membrane is true;
    generic.
- gene: human/CBFB
  row_index: 122
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus; transcription-factor subunit with no membrane association.'
- gene: human/CC2D1A
  row_index: 15
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm (ECO:0000269), nucleus, centrosome; no membrane association on record.'
- gene: human/CDK1
  row_index: 172
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus, cytoplasm, mitochondrion, centrosome; the only membrane lead is a Reactome TAS ER-membrane row
    describing CDK1 acting on membrane substrates, not residing there.'
- gene: human/CDK5RAP3
  row_index: 82
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: ER membrane (ECO:0000269, three studies) with IDA leads. Membrane is true; the specific ER membrane term
    carries it.'
- gene: human/CHMP2A
  row_index: 75
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral ESCRT-III protein (UniProt ECO:0000269) with IDA endosomal/lysosomal membrane leads; the specific terms
    carry the location.
- gene: human/CLTC
  row_index: 64
  reference: PMID:16210410
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral coated-vesicle membrane protein (UniProt ECO:0000269); specific coat and vesicle membrane terms carry
    the location.
- gene: human/CLTC
  row_index: 103
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Peripheral coated-vesicle membrane protein (UniProt ECO:0000269); specific coat and vesicle membrane terms carry
    the location.
- gene: human/CMAS
  row_index: 6
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nuclear enzyme (UniProt ECO:0000269).'
- gene: human/COLGALT1
  row_index: 8
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal enzyme (UniProt ECO:0000269).'
- gene: human/CUL3
  row_index: 170
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cullin scaffold; nuclear/Golgi/cytoplasmic in UniProt.'
- gene: human/DCTN1
  row_index: 124
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: IDA endosome membrane/retromer leads; dynactin recruited to membrane cargo.'
- gene: human/DLST
  row_index: 38
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: mitochondrial matrix E2 (UniProt).'
- gene: human/DNAJB11
  row_index: 25
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: ER lumen (ECO:0000269, four studies). Its note that DNAJB11 is ER-membrane associated applies only to a
    C-terminally epitope-tagged construct, so it is not evidence for the native protein.'
- gene: human/DNAJB6
  row_index: 29
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear/Z-line chaperone (UniProt ECO:0000269).'
- gene: human/DNAJC10
  row_index: 18
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal reductase (UniProt ECO:0000269).'
- gene: human/DNAJC13
  row_index: 10
  reference: PMID:16210410
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: early endosome membrane, peripheral (UniProt ECO:0000269).'
- gene: human/DNAJC13
  row_index: 22
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: early endosome membrane, peripheral (UniProt ECO:0000269).'
- gene: human/DNAJC3
  row_index: 29
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: endoplasmic reticulum (by similarity); GOA leads place it in the ER lumen and cytosol. No membrane association
    on record.'
- gene: human/DNAJC5
  row_index: 27
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: palmitoylated cysteine-string protein (UniProt lipid-anchor, by similarity; IDA plasma membrane).'
- gene: human/DNAJC7
  row_index: 19
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear co-chaperone (UniProt ECO:0000269).'
- gene: human/DPM1
  row_index: 26
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: Catalytic subunit of the ER-membrane DPM synthase complex, with IDA ER membrane leads. Membrane is true; the specific
    term carries it.
- gene: human/DRG2
  row_index: 19
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nuclear/cytoplasmic (UniProt ECO:0000269).'
- gene: human/DYNC1H1
  row_index: 129
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoskeleton (ECO:0000305); dynein is linked to membrane cargo through adaptors, but no protein-specific
    membrane location is on record.'
- gene: human/EIF3E
  row_index: 48
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm and PML body; translation-initiation factor with no membrane association on record.'
- gene: human/EIF5A
  row_index: 32
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear translation factor (UniProt ECO:0000269). An EXP ER-membrane lead (PMID:8660923)
    could not be checked (no cached abstract); the cached localization study (PMID:12210765) reports nuclear and cytoplasmic
    distribution only.'
- gene: human/ELAVL1
  row_index: 63
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nucleocytoplasmic RNA-binding protein.'
- gene: human/EMC8
  row_index: 25
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ER membrane, peripheral (UniProt ECO:0000269).'
- gene: human/ERO1A
  row_index: 30
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ER membrane, peripheral, lumenal side (UniProt ECO:0000269).'
- gene: human/ERP29
  row_index: 27
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: ER lumen (soluble); no membrane association on record.'
- gene: human/ETNK1
  row_index: 9
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic kinase.'
- gene: human/FANCI
  row_index: 23
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: nuclear DNA-repair protein (UniProt ECO:0000269).'
- gene: human/FASN
  row_index: 51
  reference: PMID:16210410
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic synthase (UniProt ECO:0000269).'
- gene: human/FASN
  row_index: 60
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic synthase (UniProt ECO:0000269).'
- gene: human/FEN1
  row_index: 57
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: nuclear/mitochondrial nuclease.'
- gene: human/FKBP5
  row_index: 41
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm and nucleus (by similarity); a steroid-receptor co-chaperone with no membrane association on
    record.'
- gene: human/G6PD
  row_index: 37
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: membrane, peripheral membrane protein (ECO:0000269, PubMed:743300), with IDA cytoplasmic side of plasma
    membrane lead. Membrane is true; not G6PD''s core cytosolic location.'
- gene: human/GAA
  row_index: 32
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: lysosomal lumenal enzyme; its UniProt lysosome-membrane entry comes from a lysosomal-membrane proteome
    (PubMed:17897319), not a GAA-specific study.'
- gene: human/GALK1
  row_index: 16
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic kinase.'
- gene: human/GAPDH
  row_index: 70
  reference: PMID:19946888
  previous_action: REMOVE
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: membrane (ECO:0000269, PubMed:12829261), with IDA plasma membrane and nuclear membrane leads. Membrane
    association is documented; not GAPDH''s core location.'
- gene: human/GCN1
  row_index: 27
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic, ribosome-associated.'
- gene: human/GEMIN5
  row_index: 51
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus, gems, cytoplasm (ECO:0000269); SMN-complex protein with no membrane association on record.'
- gene: human/GIGYF2
  row_index: 41
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: no UniProt location; membrane leads are IBA/IEA only.'
- gene: human/GNPAT
  row_index: 20
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: peroxisome membrane, lumenal side (UniProt ECO:0000269).'
- gene: human/GPI
  row_index: 50
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/secreted (UniProt ECO:0000269).'
- gene: human/GTPBP1
  row_index: 20
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic GTPase.'
- gene: human/GUSB
  row_index: 25
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: lysosomal lumenal enzyme.'
- gene: human/GYG1
  row_index: 32
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic glycogen-granule protein.'
- gene: human/GYS1
  row_index: 40
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic glycogen synthase.'
- gene: human/HBS1L
  row_index: 28
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic GTPase.'
- gene: human/HEXA
  row_index: 47
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: lysosomal lumenal enzyme.'
- gene: human/HEXB
  row_index: 63
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: lysosomal lumenal enzyme (UniProt ECO:0000269).'
- gene: human/HNRNPA2B1
  row_index: 52
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nucleocytoplasmic hnRNP (UniProt ECO:0000269).'
- gene: human/HSD17B4
  row_index: 39
  reference: PMID:16210410
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: peroxisomal enzyme.'
- gene: human/HSPA14
  row_index: 17
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytosol (ECO:0000269); ribosome-associated chaperone. The only membrane lead is an IBA plasma membrane
    row.'
- gene: human/HSPA2
  row_index: 41
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoskeleton/spindle (by similarity); membrane leads are IBA plasma membrane and a sperm CatSper ISS row,
    neither relevant to this cell type.'
- gene: human/HSPA8
  row_index: 172
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: lysosome membrane, peripheral (ECO:0000269) and cell membrane; IDA lysosomal membrane lead (chaperone-mediated
    autophagy). The specific terms carry the location, so the generic parent is not core.'
- gene: human/HSPD1
  row_index: 114
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: IDA plasma membrane and clathrin-coated pit leads (cell-surface Hsp60 pool); matrix is the principal
    location.'
- gene: human/IBSP
  row_index: 11
  reference: PMID:16210410
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: secreted (ECO:0000269); hydroxyapatite-binding matrix protein. No membrane association on record.'
- gene: human/IFI16
  row_index: 33
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus and cytoplasm (ECO:0000269); no membrane association on record.'
- gene: human/ILF3
  row_index: 37
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nuclear/cytoplasmic RNA-binding protein.'
- gene: human/ILK
  row_index: 83
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: cell membrane, peripheral (UniProt ECO:0000269).'
- gene: human/IMPDH2
  row_index: 28
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic enzyme (UniProt ECO:0000269).'
- gene: human/IRF4
  row_index: 40
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nuclear transcription factor.'
- gene: human/KIF5B
  row_index: 60
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cytolytic granule membrane (ECO:0000269, PubMed:24088571) and lysosome membrane, peripheral; EXP leads.
    Membrane association is documented, including in NK-cell granules.'
- gene: human/LDHA
  row_index: 38
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic enzyme.'
- gene: human/LDHB
  row_index: 41
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: mitochondrion inner membrane (ECO:0000269, PubMed:27618187), peripheral; IDA leads. Membrane association
    is documented; not LDHB''s core cytoplasmic location.'
- gene: human/LGALS3
  row_index: 65
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: secreted and associates with the cell surface (ECO:0000269, PubMed:32272059); IDA immunological synapse
    lead. Membrane association is documented; generic.'
- gene: human/LONP1
  row_index: 50
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: mitochondrial matrix protease (UniProt ECO:0000269).'
- gene: human/LONP2
  row_index: 27
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: peroxisomal matrix protease (UniProt ECO:0000269).'
- gene: human/LPXN
  row_index: 28
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: cell membrane in UniProt; IDA plasma membrane lead.'
- gene: human/LRPPRC
  row_index: 34
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: ''seems to be predominantly mitochondrial'' (ECO:0000269); its nuclear inner/outer membrane entries carry
    no evidence code and the GOA rows are IEA. No protein-specific membrane evidence.'
- gene: human/LSS
  row_index: 20
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: ER membrane, peripheral (ECO:0000269, three studies). Membrane is true; the specific ER membrane term carries
    it.'
- gene: human/MAP7D3
  row_index: 9
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: spindle/microtubules (ECO:0000269); no membrane association on record.'
- gene: human/MMS19
  row_index: 30
  reference: PMID:19946888
  previous_action: UNDECIDED
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: nucleus, spindle, centrosome (ECO:0000269); no membrane association on record.'
- gene: human/MTHFD1
  row_index: 47
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm; soluble one-carbon enzyme with no membrane association on record.'
- gene: human/MTHFD1L
  row_index: 25
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: mitochondrial enzyme.'
- gene: human/MYH9
  row_index: 100
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: IDA plasma membrane, cytoplasmic side of plasma membrane and immunological synapse leads (cortical myosin).'
- gene: human/NAA10
  row_index: 47
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear acetyltransferase.'
- gene: human/NAA15
  row_index: 24
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: UniProt explicitly reports NAA15 in free and cytoskeleton-bound but not membrane-bound polysomes.'
- gene: human/NAT10
  row_index: 51
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: nucleolar protein.'
- gene: human/NBR1
  row_index: 39
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: autophagy receptor on autophagosomes and lysosomes (UniProt ECO:0000269); Reactome places it on peroxisomal
    membranes in pexophagy. Generic.'
- gene: human/NF1
  row_index: 91
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cell membrane (ECO:0000269, PubMed:34626534) with IDA plasma membrane lead; the specific term carries the
    location, so the generic parent is not core.'
- gene: human/NPM1
  row_index: 145
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: nucleolar protein.'
- gene: human/OLA1
  row_index: 21
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: cytoplasmic/nuclear ATPase.'
- gene: human/P3H1
  row_index: 20
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal/secreted enzyme.'
- gene: human/P4HA1
  row_index: 16
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal enzyme.'
- gene: human/PAICS
  row_index: 37
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic enzyme.'
- gene: human/PDCD6IP
  row_index: 70
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ESCRT-associated adaptor at the midbody ring and immunological synapse (IDA lead); membrane-associated
    in function, generic as a term.'
- gene: human/PGK1
  row_index: 48
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic/matrix glycolytic enzyme; the IDA membrane-raft lead is itself a raft proteome.'
- gene: human/PICALM
  row_index: 82
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cell membrane and clathrin-coated pit (ECO:0000269) with IDA leads; the specific terms carry the location,
    so the generic parent is not core.'
- gene: human/PIK3C3
  row_index: 94
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: ACCEPT
  changed: false
  basis: 'Confirmed: PIK3C3 makes PI3P on endosomal and autophagic membranes, so membrane association is part of its catalytic
    mechanism (earlier review). Its only experimental membrane lead is an IDA plasma membrane row, which is not where it acts,
    so no specific term carries this.'
- gene: human/PIK3R1
  row_index: 351
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: p85 recruited to phosphotyrosine receptors at the plasma membrane (Reactome TAS leads); generic.'
- gene: human/PKMYT1
  row_index: 41
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ER and Golgi membrane, peripheral (UniProt ECO:0000269).'
- gene: human/PMVK
  row_index: 17
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic kinase (UniProt ECO:0000269).'
- gene: human/POFUT1
  row_index: 14
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: ER-lumenal fucosyltransferase (UniProt ER, by similarity).'
- gene: human/PPIB
  row_index: 29
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: ER lumen (ECO:0000269); soluble cyclophilin with no membrane association on record.'
- gene: human/RAD21
  row_index: 120
  reference: PMID:19946888
  previous_action: REMOVE
  decision: REMOVE
  changed: false
  basis: 'Confirmed: nuclear cohesin subunit.'
- gene: human/RASAL3
  row_index: 14
  reference: PMID:19946888
  previous_action: ACCEPT
  decision: KEEP_AS_NON_CORE
  changed: true
  basis: 'UniProt: cytoplasm and cell cortex (ECO:0000269) with IDA plasma membrane and cytoplasmic side of membrane leads;
    the specific terms carry the location, so the generic parent is not core.'
- gene: human/RPL18A
  row_index: 32
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: Cytosolic ribosomal protein (UniProt ECO:0000269); ribosomes on the rough ER are attached via the translocon but
    are not membrane constituents. Same call as RPS3.
- gene: human/RPS3
  row_index: 134
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: cytosolic ribosomal protein.'
- gene: human/SCP2
  row_index: 40
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: peroxisomal/cytoplasmic lipid-transfer protein.'
- gene: human/STAU2
  row_index: 42
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: MARK_AS_OVER_ANNOTATED
  changed: true
  basis: 'UniProt: cytoplasm, nucleus, nucleolus, ER (no membrane entry); membrane leads are IBA/IEA only. RNP association
    with the ER does not make STAU2 a membrane protein.'
- gene: human/TTK
  row_index: 25
  reference: PMID:19946888
  previous_action: MARK_AS_OVER_ANNOTATED
  decision: MARK_AS_OVER_ANNOTATED
  changed: false
  basis: 'Confirmed: kinetochore/spindle kinase.'
- gene: human/UFL1
  row_index: 92
  reference: PMID:16210410
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: ER membrane (UniProt ECO:0000269, six studies).'
- gene: human/USO1
  row_index: 41
  reference: PMID:19946888
  previous_action: KEEP_AS_NON_CORE
  decision: KEEP_AS_NON_CORE
  changed: false
  basis: 'Confirmed: Golgi membrane, peripheral (UniProt ECO:0000269).'