gene	protein	taxon	term	label	rule	verdict	exact_concept	modules	gaps	steps_filled	other_modules	review_action
9AVES/TAS1R1	A0A7L3NBT4	689266	GO:0050909	sensory perception of taste	ARBA:ARBA00028227	NO_MODULE	False				gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
9AVES/TAS1R3	A0A7L3N407	689266	GO:0050909	sensory perception of taste	ARBA:ARBA00028227	NO_MODULE	False				gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
9CAUD/g022	I7J3R9	1206556	GO:0071897	DNA biosynthetic process	ARBA:ARBA00028515	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|muth_independent_mismatch_repair|sphingolipid_de_novo_synthesis|viral_factory	KEEP_AS_NON_CORE
9POAL/CDT1	B5BSU2	62337	GO:0010038	response to metal ion	ARBA:ARBA00028342	NO_MODULE	False					KEEP_AS_NON_CORE
9POAL/NCGR_LOCUS1270	A0A811M8A5	422564	GO:0005985	sucrose metabolic process	ARBA:ARBA00045052	NO_MODULE	False				entner_doudoroff_and_gluconeogenesis|gluconeogenesis|gluconeogenesis_human|gluconeogenesis_human_substrates|gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	UNDECIDED
9POAL/NCGR_LOCUS29329	A0A811PKG6	422564	GO:0006531	aspartate metabolic process	ARBA:ARBA00085438	NOT_ENTAILED	False	aspartate_asparagine_metabolism			aspartate_family_threonine_biosynthesis|coenzyme_a_biosynthesis|complex_i_assembly_factors|sphingolipid_de_novo_synthesis	ACCEPT
ACET2/P10477	P10477	203119	GO:2000884	glucomannan catabolic process	ARBA:ARBA00085700	NO_MODULE	False				bacterial_flavonoid_degradation|bacterial_sulfoquinovose_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
ARAHY/A0A444Z7V7	A0A444Z7V7	3818	GO:0009409	response to cold	ARBA:ARBA00028088	NO_MODULE	False				bacterial_cellulose_biosynthesis|osmoregulated_periplasmic_glucan_biosynthesis	MARK_AS_OVER_ANNOTATED
ARATH/ABCB19	Q9LJX0	3702	GO:0008361	regulation of cell size	ARBA:ARBA00091970	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009555	pollen development	ARBA:ARBA00092333	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009637	response to blue light	ARBA:ARBA00026676	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009640	photomorphogenesis	ARBA:ARBA00091863	NOT_ENTAILED	True	phytochrome_photomorphogenesis			auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009733	response to auxin	ARBA:ARBA00028751	NOT_ENTAILED	False	auxin_nuclear_signaling			auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009741	response to brassinosteroid	ARBA:ARBA00085261	NOT_ENTAILED	False	brassinosteroid_signaling			auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0009926	auxin polar transport	ARBA:ARBA00084439	ENTAILED	True	auxin_polar_transport		auxin_polar_transport:abcb19_auxin_export|auxin_polar_transport:pin1_efflux|auxin_polar_transport:pin2_efflux	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
ARATH/ABCB19	Q9LJX0	3702	GO:0043481	anthocyanin accumulation in tissues in response to UV light	ARBA:ARBA00085884	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0048443	stamen development	ARBA:ARBA00089674	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0048461	flower structural organization	ARBA:ARBA00095377	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0051510	regulation of unidimensional cell growth	ARBA:ARBA00088642	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:0090627	plant epidermal cell differentiation	ARBA:ARBA00087997	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABCB19	Q9LJX0	3702	GO:1900459	positive regulation of brassinosteroid mediated signaling pathway	ARBA:ARBA00093743	NO_MODULE	False				auxin_polar_transport|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/ABI5	Q9SJN0	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	auxin_nuclear_signaling|brassinosteroid_signaling|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis		auxin_nuclear_signaling:arf5_activator|brassinosteroid_signaling:bes1_tf|brassinosteroid_signaling:bzr1_tf|gibberellin_della_signaling:pif_transcription_factor|jasmonate_coi1_jaz_signaling:myc_transcription_factor|phytochrome_photomorphogenesis:hy5_transcription_factor|phytochrome_photomorphogenesis:pif1_transcription_factor|phytochrome_photomorphogenesis:pif3_transcription_factor|phytochrome_photomorphogenesis:pif4_transcription_factor	bacterial_recbcd_end_resection|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage_development|strigolactone_signaling_shoot_branching|trichome_initiation_mbw|verna	MARK_AS_OVER_ANNOTATED
ARATH/ABI5	Q9SJN0	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/ABI5	Q9SJN0	3702	GO:0009651	response to salt stress	ARBA:ARBA00026582	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/ABI5	Q9SJN0	3702	GO:0009737	response to abscisic acid	ARBA:ARBA00033526	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/ABI5	Q9SJN0	3702	GO:0009845	seed germination	ARBA:ARBA00084883	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/ABI5	Q9SJN0	3702	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	brassinosteroid_signaling|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|strigolactone_signaling_shoot_branching		brassinosteroid_signaling:bes1_tf|brassinosteroid_signaling:bzr1_tf|gibberellin_della_signaling:pif_transcription_factor|jasmonate_coi1_jaz_signaling:myc_transcription_factor|strigolactone_signaling_shoot_branching:brc1_tcp_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage_development|trichome_initi	MARK_AS_OVER_ANNOTATED
ARATH/AFB2	Q9LW29	3702	GO:0009733	response to auxin	ARBA:ARBA00028751	ENTAILED	False	auxin_nuclear_signaling		auxin_nuclear_signaling:tir1_afb_receptor|auxin_nuclear_signaling:tir1_afb_scf_adaptor	ethylene_signaling|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|plant_circadian_clock_oscillator|pyruvate_metabolism|strigolactone_signaling_	ACCEPT
ARATH/AG	P17839	3702	GO:0048440		ARBA:ARBA00089672	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/AGO1	O04379	3702	GO:0010016	shoot system morphogenesis	ARBA:ARBA00091374	NO_MODULE	False				autonomous_flowering_pathway	KEEP_AS_NON_CORE
ARATH/AGO1	O04379	3702	GO:0051607	defense response to virus	ARBA:ARBA00026923	NO_MODULE	False				autonomous_flowering_pathway	MODIFY
ARATH/AHK2	Q9C5U2	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0009651	response to salt stress	ARBA:ARBA00026582	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0009909	regulation of flower development	ARBA:ARBA00043323	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0010029	regulation of seed germination	ARBA:ARBA00091417	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0010087	phloem or xylem histogenesis	ARBA:ARBA00091454	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0010271	regulation of chlorophyll catabolic process	ARBA:ARBA00090628	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0034757	negative regulation of iron ion transport	ARBA:ARBA00085303	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0048509	regulation of meristem development	ARBA:ARBA00091779	NOT_ENTAILED	False	autonomous_flowering_pathway			brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0070417	cellular response to cold	ARBA:ARBA00029183	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0071215	cellular response to abscisic acid stimulus	ARBA:ARBA00090666	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK2	Q9C5U2	3702	GO:0080117	secondary growth	ARBA:ARBA00084428	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0009651	response to salt stress	ARBA:ARBA00026582	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0009909	regulation of flower development	ARBA:ARBA00043323	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0010029	regulation of seed germination	ARBA:ARBA00091417	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0010087	phloem or xylem histogenesis	ARBA:ARBA00091454	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0010271	regulation of chlorophyll catabolic process	ARBA:ARBA00090628	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0034757	negative regulation of iron ion transport	ARBA:ARBA00085303	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0048509	regulation of meristem development	ARBA:ARBA00091779	NOT_ENTAILED	False	autonomous_flowering_pathway			brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0070417	cellular response to cold	ARBA:ARBA00029183	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0071215	cellular response to abscisic acid stimulus	ARBA:ARBA00090666	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK3	Q9C5U1	3702	GO:0080117	secondary growth	ARBA:ARBA00084428	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0006970	response to osmotic stress	ARBA:ARBA00026252	NO_MODULE	False				brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0010029	regulation of seed germination	ARBA:ARBA00091417	NO_MODULE	False				brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	MARK_AS_OVER_ANNOTATED
ARATH/AHK4	Q9C5U0	3702	GO:0048509	regulation of meristem development	ARBA:ARBA00091779	NOT_ENTAILED	False	autonomous_flowering_pathway			brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0048831	regulation of shoot system development	ARBA:ARBA00043299	NO_MODULE	False				brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	KEEP_AS_NON_CORE
ARATH/AHK4	Q9C5U0	3702	GO:0160109	plant gross anatomical part developmental process	ARBA:ARBA00098140	NOT_ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage_development			brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|strigol	MARK_AS_OVER_ANNOTATED
ARATH/AHK4	Q9C5U0	3702	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	brassinosteroid_signaling|strigolactone_signaling_shoot_branching		brassinosteroid_signaling:bsk1_relay_kinase|strigolactone_signaling_shoot_branching:d14_sl_receptor	chitin_perception|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|two_component_relay	MARK_AS_OVER_ANNOTATED
ARATH/AHP1	Q9ZNV9	3702	GO:0009736	cytokinin-activated signaling pathway	ARBA:ARBA00028777	ENTAILED	True	cytokinin_two_component_signaling		cytokinin_two_component_signaling:ahp1_phosphotransfer	brassinosteroid_signaling|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|two_component_relay	ACCEPT
ARATH/AHP1	Q9ZNV9	3702	GO:0160109	plant gross anatomical part developmental process	ARBA:ARBA00098140	NOT_ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage_development			brassinosteroid_signaling|coenzyme_a_biosynthesis|cytokinin_two_component_signaling|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|two_component_relay	MARK_AS_OVER_ANNOTATED
ARATH/AOP2	Q945B5	3702	GO:0019761	glucosinolate biosynthetic process	ARBA:ARBA00085760	ENTAILED	True	aliphatic_glucosinolate_myrosinase_defense		aliphatic_glucosinolate_myrosinase_defense:aop2_activity	complex_i_assembly_factors	ACCEPT
ARATH/AP3	P35632	3702	GO:0048437	floral organ development	ARBA:ARBA00026899	ENTAILED	False	floral_organ_identity_abce		floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0009611	response to wounding	ARBA:ARBA00026469	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	MARK_AS_OVER_ANNOTATED
ARATH/ARR12	P62598	3702	GO:0010082	regulation of root meristem growth	ARBA:ARBA00091464	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0010380	regulation of chlorophyll biosynthetic process	ARBA:ARBA00093133	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0010492	maintenance of shoot apical meristem identity	ARBA:ARBA00092785	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0031537	regulation of anthocyanin metabolic process	ARBA:ARBA00085490	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0048367	shoot system development	ARBA:ARBA00026422	ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce		floral_meristem_identity:ap2_floral_meristem_establishment|floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|s	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0080022	primary root development	ARBA:ARBA00084779	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR12	P62598	3702	GO:0080036	regulation of cytokinin-activated signaling pathway	ARBA:ARBA00084807	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	MODIFY
ARATH/ARR12	P62598	3702	GO:0080113	regulation of seed growth	ARBA:ARBA00084427	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	KEEP_AS_NON_CORE
ARATH/ARR5	Q9SB04	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_	MARK_AS_OVER_ANNOTATED
ARATH/AT1G74310	P42730	3702	GO:0009408	response to heat	ARBA:ARBA00028092	NOT_ENTAILED	False	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
ARATH/AT5G02500	P22953	3702	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	autonomous_flowering_pathway|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
ARATH/AT5G02500	P22953	3702	GO:0009615	response to virus	ARBA:ARBA00026492	NO_MODULE	False				autonomous_flowering_pathway|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolis	KEEP_AS_NON_CORE
ARATH/BAM1	O49545	3702	GO:0009934	regulation of meristem structural organization	ARBA:ARBA00084446	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	ACCEPT
ARATH/BAM1	O49545	3702	GO:0010075	regulation of meristem growth	ARBA:ARBA00091443	ENTAILED	False	shoot_meristem_clv_wus_feedback		shoot_meristem_clv_wus_feedback:clv3_peptide	auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	ACCEPT
ARATH/BAM1	O49545	3702	GO:0048229	gametophyte development	ARBA:ARBA00089744	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/BAM1	O49545	3702	GO:0048437	floral organ development	ARBA:ARBA00026899	NOT_ENTAILED	False	floral_organ_identity_abce			auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/BES1	Q9LN63	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/BRC1	A1YKT1	3702	GO:0160109	plant gross anatomical part developmental process	ARBA:ARBA00098140	ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage_development|trichome_initiation_mbw		floral_meristem_identity:ap2_floral_meristem_establishment|floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf|root_radial_patterning_shr_scr:jkd_tf|root_radial_patterning_shr_scr:mgp_tf|shoot_meristem_clv_wus_feedback:wus_tf|stomatal_lineage_development:fama_tf|stomatal_lineage_development:mute_tf|trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching|vernalization_flc_silencing	MARK_AS_OVER_ANNOTATED
ARATH/BRI1	O22476	3702	GO:0009416	response to light stimulus	ARBA:ARBA00028128	ENTAILED	False	phytochrome_photomorphogenesis		phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/BRI1	O22476	3702	GO:0009791	post-embryonic development	ARBA:ARBA00029007	ENTAILED	False	phytochrome_photomorphogenesis|stomatal_lineage_development		phytochrome_photomorphogenesis:spa1_pif1_kinase|stomatal_lineage_development:ice1_partner	auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/BZR1	Q8S307	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/CCA1	P92973	3702	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/CERK1	A8R7E6	3702	GO:0009617	response to bacterium	ARBA:ARBA00026494	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/CERK1	A8R7E6	3702	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	brassinosteroid_signaling|strigolactone_signaling_shoot_branching		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|strigolactone_signaling_shoot_branching:d14_sl_receptor	auxin_polar_transport|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phyt	MARK_AS_OVER_ANNOTATED
ARATH/CLF	P93831	3702	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	MODULE_INCOMPLETE	False	autonomous_flowering_pathway	autonomous_flowering_pathway:coolair_proximal_polyadenylation	autonomous_flowering_pathway:fpa_poly_a_site_choice	bacterial_methionine_cycle|methionine_cycle|root_radial_patterning_shr_scr|vernalization_flc_silencing	ACCEPT
ARATH/CLF	P93831	3702	GO:0141044	epigenetic programming in the endosperm	ARBA:ARBA00095392	NO_MODULE	False				autonomous_flowering_pathway|bacterial_methionine_cycle|methionine_cycle|root_radial_patterning_shr_scr|vernalization_flc_silencing	KEEP_AS_NON_CORE
ARATH/CLV1	Q9SYQ8	3702	GO:0032502	developmental process	ARBA:ARBA00028739	ENTAILED	False	phytochrome_photomorphogenesis|shoot_meristem_clv_wus_feedback		phytochrome_photomorphogenesis:spa1_pif1_kinase|shoot_meristem_clv_wus_feedback:clv3_peptide	auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	MODIFY
ARATH/CLV1	Q9SYQ8	3702	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	ENTAILED	False	shoot_meristem_clv_wus_feedback		shoot_meristem_clv_wus_feedback:clv3_peptide	auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	MODIFY
ARATH/CLV2	O80809	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	NOT_ENTAILED	False	auxin_nuclear_signaling|brassinosteroid_signaling|chitin_perception|cytokinin_two_component_signaling|erk5_cascade			strigolactone_signaling_shoot_branching	MODIFY
ARATH/CPC	O22059	3702	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	floral_organ_identity_abce		floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_	MARK_AS_OVER_ANNOTATED
ARATH/CPC	O22059	3702	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce|root_radial_patterning_shr_scr		floral_meristem_identity:ap2_floral_meristem_establishment|floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf|root_radial_patterning_shr_scr:jkd_tf|root_radial_patterning_shr_scr:mgp_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|shoot_meristem_clv_wus_feedback|stomatal_lineage_development|strigolactone_	MARK_AS_OVER_ANNOTATED
ARATH/CPC	O22059	3702	GO:0090558	plant epidermis development	ARBA:ARBA00047265	ENTAILED	False	stomatal_lineage_development|trichome_initiation_mbw		stomatal_lineage_development:fama_tf|stomatal_lineage_development:mute_tf|trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/CPC	O22059	3702	GO:0090627	plant epidermal cell differentiation	ARBA:ARBA00087997	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/CRY1	Q43125	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	MARK_AS_OVER_ANNOTATED
ARATH/CRY1	Q43125	3702	GO:0009638	phototropism	ARBA:ARBA00091921	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0009646	response to absence of light	ARBA:ARBA00091861	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0009785	blue light signaling pathway	ARBA:ARBA00028968	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	ACCEPT
ARATH/CRY1	Q43125	3702	GO:0009791	post-embryonic development	ARBA:ARBA00029007	ENTAILED	False	photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis		photoperiodic_flowering_co_ft:cry2_blue_light_receptor|photoperiodic_flowering_co_ft:fkf1_blue_light_photoreceptor|phytochrome_photomorphogenesis:cry1_blue_light_photoreceptor	brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|sphingolip	MODIFY
ARATH/CRY1	Q43125	3702	GO:0010075	regulation of meristem growth	ARBA:ARBA00091443	NOT_ENTAILED	False	shoot_meristem_clv_wus_feedback			brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0010118	stomatal movement	ARBA:ARBA00090909	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0010244	response to low fluence blue light stimulus by blue low-fluence system	ARBA:ARBA00090587	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0010617	circadian regulation of calcium ion oscillation	ARBA:ARBA00091901	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0042752	regulation of circadian rhythm	ARBA:ARBA00088520	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:0048580	regulation of post-embryonic development	ARBA:ARBA00043383	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	MODIFY
ARATH/CRY1	Q43125	3702	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	photoperiodic_flowering_co_ft		photoperiodic_flowering_co_ft:cry2_blue_light_receptor|photoperiodic_flowering_co_ft:fkf1_blue_light_photoreceptor	brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator	MODIFY
ARATH/CRY1	Q43125	3702	GO:0072387	flavin adenine dinucleotide metabolic process	ARBA:ARBA00090789	NOT_ENTAILED	False	flavin_cofactor_biosynthesis|riboflavin_biosynthesis|riboflavin_uptake_and_cofactor_synthesis			brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	MODIFY
ARATH/CRY1	Q43125	3702	GO:1901371	regulation of leaf morphogenesis	ARBA:ARBA00092524	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:1902347	response to strigolactone	ARBA:ARBA00089248	ENTAILED	False	strigolactone_signaling_shoot_branching		strigolactone_signaling_shoot_branching:d14_sl_receptor	brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY1	Q43125	3702	GO:2000377	regulation of reactive oxygen species metabolic process	ARBA:ARBA00086857	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peptidoglycan_recycling|phosphotyrosine_adaptor_recruitment|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|pl	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0009638	phototropism	ARBA:ARBA00091921	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0009646	response to absence of light	ARBA:ARBA00091861	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0009785	blue light signaling pathway	ARBA:ARBA00028968	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	ACCEPT
ARATH/CRY2	Q96524	3702	GO:0009791	post-embryonic development	ARBA:ARBA00029007	ENTAILED	False	photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis		photoperiodic_flowering_co_ft:cry2_blue_light_receptor|photoperiodic_flowering_co_ft:fkf1_blue_light_photoreceptor|phytochrome_photomorphogenesis:cry1_blue_light_photoreceptor	heat_shock_response|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	MARK_AS_OVER_ANNOTATED
ARATH/CRY2	Q96524	3702	GO:0010075	regulation of meristem growth	ARBA:ARBA00091443	NOT_ENTAILED	False	shoot_meristem_clv_wus_feedback			heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0010118	stomatal movement	ARBA:ARBA00090909	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0010244	response to low fluence blue light stimulus by blue low-fluence system	ARBA:ARBA00090587	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	ACCEPT
ARATH/CRY2	Q96524	3702	GO:0010617	circadian regulation of calcium ion oscillation	ARBA:ARBA00091901	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0042752	regulation of circadian rhythm	ARBA:ARBA00088520	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:0048580	regulation of post-embryonic development	ARBA:ARBA00043383	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	MARK_AS_OVER_ANNOTATED
ARATH/CRY2	Q96524	3702	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	photoperiodic_flowering_co_ft		photoperiodic_flowering_co_ft:cry2_blue_light_receptor|photoperiodic_flowering_co_ft:fkf1_blue_light_photoreceptor	heat_shock_response|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	MARK_AS_OVER_ANNOTATED
ARATH/CRY2	Q96524	3702	GO:0072387	flavin adenine dinucleotide metabolic process	ARBA:ARBA00090789	NOT_ENTAILED	False	flavin_cofactor_biosynthesis|riboflavin_biosynthesis|riboflavin_uptake_and_cofactor_synthesis			heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	MODIFY
ARATH/CRY2	Q96524	3702	GO:1901371	regulation of leaf morphogenesis	ARBA:ARBA00092524	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:1902347	response to strigolactone	ARBA:ARBA00089248	ENTAILED	False	strigolactone_signaling_shoot_branching		strigolactone_signaling_shoot_branching:d14_sl_receptor	heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator	KEEP_AS_NON_CORE
ARATH/CRY2	Q96524	3702	GO:2000377	regulation of reactive oxygen species metabolic process	ARBA:ARBA00086857	NO_MODULE	False				heat_shock_response|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	KEEP_AS_NON_CORE
ARATH/CYCD6-1	Q9ZR04	3702	GO:0010440	stomatal lineage progression	ARBA:ARBA00092641	NOT_ENTAILED	True	stomatal_lineage_development			g1_s_transition|root_radial_patterning_shr_scr|sphingolipid_de_novo_synthesis	REMOVE
ARATH/CYP79B2	O81346	3702	GO:0044272	sulfur compound biosynthetic process	ARBA:ARBA00028512	ENTAILED	False	aliphatic_glucosinolate_myrosinase_defense|camalexin_biosynthesis		aliphatic_glucosinolate_myrosinase_defense:cyp83a1_activity|camalexin_biosynthesis:cyp79b_activity	complex_i_assembly_factors|mitochondrial_complex_ii	MODIFY
ARATH/CYP79B3	Q501D8	3702	GO:0044272	sulfur compound biosynthetic process	ARBA:ARBA00028512	ENTAILED	False	aliphatic_glucosinolate_myrosinase_defense|camalexin_biosynthesis		aliphatic_glucosinolate_myrosinase_defense:cyp83a1_activity|camalexin_biosynthesis:cyp79b_activity	complex_i_assembly_factors|mitochondrial_complex_ii	MODIFY
ARATH/DCL1	Q9SP32	3702	GO:0009616	RNAi-mediated antiviral immune response	ARBA:ARBA00095379	NO_MODULE	False				autonomous_flowering_pathway|bacterial_recbcd_end_resection|gpi_anchor_remodeling|phenylacetate_catabolism|vernalization_flc_silencing	KEEP_AS_NON_CORE
ARATH/DCL1	Q9SP32	3702	GO:0010267	ta-siRNA processing	ARBA:ARBA00090672	NO_MODULE	False				autonomous_flowering_pathway|bacterial_recbcd_end_resection|gpi_anchor_remodeling|phenylacetate_catabolism|vernalization_flc_silencing	KEEP_AS_NON_CORE
ARATH/DCL1	Q9SP32	3702	GO:0035196	miRNA processing	ARBA:ARBA00028690	NO_MODULE	False				autonomous_flowering_pathway|bacterial_recbcd_end_resection|gpi_anchor_remodeling|phenylacetate_catabolism|vernalization_flc_silencing	MODIFY
ARATH/EBF1	Q9SKK0	3702	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False					ACCEPT
ARATH/EBF1	Q9SKK0	3702	GO:0009723	response to ethylene	ARBA:ARBA00028729	NOT_ENTAILED	False	ethylene_signaling				ACCEPT
ARATH/EBF1	Q9SKK0	3702	GO:0010105	negative regulation of ethylene-activated signaling pathway	ARBA:ARBA00027582	NO_MODULE	False					ACCEPT
ARATH/EBF2	Q708Y0	3702	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False					ACCEPT
ARATH/EBF2	Q708Y0	3702	GO:0009723	response to ethylene	ARBA:ARBA00028729	NOT_ENTAILED	False	ethylene_signaling				ACCEPT
ARATH/EBF2	Q708Y0	3702	GO:0010105	negative regulation of ethylene-activated signaling pathway	ARBA:ARBA00027582	NO_MODULE	False					ACCEPT
ARATH/EFR	C0LGT6	3702	GO:0009617	response to bacterium	ARBA:ARBA00026494	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	KEEP_AS_NON_CORE
ARATH/EFR	C0LGT6	3702	GO:0031349	positive regulation of defense response	ARBA:ARBA00028260	ENTAILED	False	chitin_perception		chitin_perception:atcerk1_kinase_activity|chitin_perception:bik1_kinase|chitin_perception:oscerk1_kinase_activity|chitin_perception:pbl27_kinase	auxin_polar_transport|brassinosteroid_signaling|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phytochrome_phot	ACCEPT
ARATH/EGL3	Q9CAD0	3702	GO:0009867	jasmonic acid mediated signaling pathway	ARBA:ARBA00033508	ENTAILED	True	jasmonate_coi1_jaz_signaling		jasmonate_coi1_jaz_signaling:myc_transcription_factor	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wu	KEEP_AS_NON_CORE
ARATH/EGL3	Q9CAD0	3702	GO:0010026	trichome differentiation	ARBA:ARBA00091409	ENTAILED	True	trichome_initiation_mbw		trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/EGL3	Q9CAD0	3702	GO:0090628	plant epidermal cell fate specification	ARBA:ARBA00095292	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/EIL1	Q9SLH0	3702	GO:0009873	ethylene-activated signaling pathway	ARBA:ARBA00084995	NOT_ENTAILED	True	ethylene_signaling			auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/EPF2	Q8LC53	3702	GO:0160109	plant gross anatomical part developmental process	ARBA:ARBA00098140	ENTAILED	False	stomatal_lineage_development		stomatal_lineage_development:epf2_ligand		KEEP_AS_NON_CORE
ARATH/ERECTA	Q42371	3702	GO:0010103	stomatal complex morphogenesis	ARBA:ARBA00090926	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	MODIFY
ARATH/ERECTA	Q42371	3702	GO:0048827	phyllome development	ARBA:ARBA00034933	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	KEEP_AS_NON_CORE
ARATH/ERECTA	Q42371	3702	GO:0090567	reproductive shoot system development	ARBA:ARBA00028307	NOT_ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce			auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	KEEP_AS_NON_CORE
ARATH/ERS1	Q38846	3702	GO:0010105	negative regulation of ethylene-activated signaling pathway	ARBA:ARBA00027582	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|ethylene_signaling|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	ACCEPT
ARATH/ESP	Q8RY71	3702	GO:0019762	glucosinolate catabolic process	ARBA:ARBA00043525	NOT_ENTAILED	True	aliphatic_glucosinolate_myrosinase_defense			heat_shock_response|sphingolipid_de_novo_synthesis	ACCEPT
ARATH/ESP	Q8RY71	3702	GO:0080028	nitrile biosynthetic process	ARBA:ARBA00043356	NO_MODULE	False				heat_shock_response|sphingolipid_de_novo_synthesis	ACCEPT
ARATH/ETR1	P49333	3702	GO:0010105	negative regulation of ethylene-activated signaling pathway	ARBA:ARBA00027582	NO_MODULE	False				brassinosteroid_signaling|coenzyme_a_biosynthesis|ethylene_signaling|heat_shock_response|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching|two_component_relay	ACCEPT
ARATH/FAMA	Q56YJ8	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_linea	ACCEPT
ARATH/FCA	O04425	3702	GO:0009909	regulation of flower development	ARBA:ARBA00043323	NO_MODULE	False				autonomous_flowering_pathway	ACCEPT
ARATH/FIE	Q9LT47	3702	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NOT_ENTAILED	False	autonomous_flowering_pathway|vernalization_flc_silencing			auxin_nuclear_signaling|brassinosteroid_signaling|complex_i_assembly_factors|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_	ACCEPT
ARATH/FKF1	Q9C9W9	3702	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False					ACCEPT
ARATH/FKF1	Q9C9W9	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	NOT_ENTAILED	True	plant_circadian_clock_oscillator				KEEP_AS_NON_CORE
ARATH/FKF1	Q9C9W9	3702	GO:0009637	response to blue light	ARBA:ARBA00026676	NO_MODULE	False					ACCEPT
ARATH/FLC	Q9S7Q7	3702	GO:0009909	regulation of flower development	ARBA:ARBA00043323	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_	ACCEPT
ARATH/FLS2	Q9FL28	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	brassinosteroid_signaling|chitin_perception|ethylene_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|phytochrome_photomorphogenesis		brassinosteroid_signaling:bak1_coreceptor|brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|chitin_perception:atcerk1_kinase_activity|chitin_perception:bik1_kinase|chitin_perception:oscerk1_kinase_activity|chitin_perception:pbl27_kinase|ethylene_signaling:ctr1_kinase|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|coenzyme_a_biosynthesis|g2_m_transition|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|shoot_meristem_clv_wus_feedback|sphingolipid_de_novo_synthesis|stomatal_lineage_development|stri	MODIFY
ARATH/FLS2	Q9FL28	3702	GO:0071555	cell wall organization	ARBA:ARBA00027619	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	MODIFY
ARATH/FVE	O22607	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				autonomous_flowering_pathway	ACCEPT
ARATH/FVE	O22607	3702	GO:0010629	negative regulation of gene expression	ARBA:ARBA00026647	MODULE_INCOMPLETE	False	autonomous_flowering_pathway	autonomous_flowering_pathway:coolair_proximal_polyadenylation	autonomous_flowering_pathway:fve_histone_binding_hdac|autonomous_flowering_pathway:fve_histone_binding_prc2		ACCEPT
ARATH/FVE	O22607	3702	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	MODULE_INCOMPLETE	False	autonomous_flowering_pathway	autonomous_flowering_pathway:coolair_proximal_polyadenylation	autonomous_flowering_pathway:fve_histone_binding_hdac|autonomous_flowering_pathway:fve_histone_binding_prc2		ACCEPT
ARATH/GAI	Q9LQT8	3702	GO:0009740	gibberellic acid mediated signaling pathway	ARBA:ARBA00028868	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_photomorphogenes	ACCEPT
ARATH/GGP1	Q9M0A7	3702	GO:0019760	glucosinolate metabolic process	ARBA:ARBA00043526	ENTAILED	False	aliphatic_glucosinolate_myrosinase_defense		aliphatic_glucosinolate_myrosinase_defense:ggp1_activity	camalexin_biosynthesis|phenylacetate_catabolism|protease_activation_cascade	MODIFY
ARATH/GID1A	Q9MAA7	3702	GO:0009939	positive regulation of gibberellic acid mediated signaling pathway	ARBA:ARBA00084445	NO_MODULE	False				gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phenylacetate_catabolism	ACCEPT
ARATH/GID1A	Q9MAA7	3702	GO:0048444	floral organ morphogenesis	ARBA:ARBA00089680	NOT_ENTAILED	False	floral_organ_identity_abce			gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/GID1A	Q9MAA7	3702	GO:0048530	fruit morphogenesis	ARBA:ARBA00091695	NO_MODULE	False				gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/GID1B	Q9LYC1	3702	GO:0048530	fruit morphogenesis	ARBA:ARBA00091695	NO_MODULE	False				gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/GID1C	Q940G6	3702	GO:0048530	fruit morphogenesis	ARBA:ARBA00091695	NO_MODULE	False				gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/GL1	P27900	3702	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	trichome_initiation_mbw		trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_	MODIFY
ARATH/GL1	P27900	3702	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	floral_meristem_identity|floral_organ_identity_abce|root_radial_patterning_shr_scr		floral_meristem_identity:ap2_floral_meristem_establishment|floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf|root_radial_patterning_shr_scr:jkd_tf|root_radial_patterning_shr_scr:mgp_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|shoot_meristem_clv_wus_feedback|stomatal_lineage_development|strigolactone_signaling_shoot_branchi	MODIFY
ARATH/GL1	P27900	3702	GO:0090558	plant epidermis development	ARBA:ARBA00047265	ENTAILED	False	stomatal_lineage_development|trichome_initiation_mbw		stomatal_lineage_development:fama_tf|stomatal_lineage_development:mute_tf|trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_	ACCEPT
ARATH/GL2	P46607	3702	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	trichome_initiation_mbw		trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator|trichome_initiation_mbw:gl2_hdzip_effector|trichome_initiation_mbw:gl3_bhlh_bridge	autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_	MODIFY
ARATH/GL3	Q9FN69	3702	GO:0009867	jasmonic acid mediated signaling pathway	ARBA:ARBA00033508	ENTAILED	True	jasmonate_coi1_jaz_signaling		jasmonate_coi1_jaz_signaling:myc_transcription_factor	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lin	KEEP_AS_NON_CORE
ARATH/GL3	Q9FN69	3702	GO:0010026	trichome differentiation	ARBA:ARBA00091409	ENTAILED	True	trichome_initiation_mbw		trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_	ACCEPT
ARATH/GL3	Q9FN69	3702	GO:0090628	plant epidermal cell fate specification	ARBA:ARBA00095292	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_	ACCEPT
ARATH/GSTF11	Q96324	3702	GO:0009407	toxin catabolic process	ARBA:ARBA00028091	NO_MODULE	False				aliphatic_glucosinolate_myrosinase_defense|camalexin_biosynthesis|methionine_biosynthesis	KEEP_AS_NON_CORE
ARATH/GSTF6	P42760	3702	GO:0009407	toxin catabolic process	ARBA:ARBA00028091	NO_MODULE	False				aliphatic_glucosinolate_myrosinase_defense|camalexin_biosynthesis|methionine_biosynthesis	KEEP_AS_NON_CORE
ARATH/GSTU20	Q8L7C9	3702	GO:0009407	toxin catabolic process	ARBA:ARBA00028091	NO_MODULE	False				aliphatic_glucosinolate_myrosinase_defense|camalexin_biosynthesis|methionine_biosynthesis	KEEP_AS_NON_CORE
ARATH/HEN1	Q9C5Q8	3702	GO:0016070	RNA metabolic process	ARBA:ARBA00028985	NO_MODULE	False				methionine_cycle|methylcitrate_cycle|phenylacetate_catabolism|retinoid_visual_cycle	MODIFY
ARATH/HKT1	Q84TI7	3702	GO:0006813	potassium ion transport	ARBA:ARBA00028465	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
ARATH/HSP17.6A	Q9XIE3	3702	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade				KEEP_AS_NON_CORE
ARATH/HSP17.7	O81822	3702	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade				ACCEPT
ARATH/ICS1	Q9S7H8	3702	GO:0042372	phylloquinone biosynthetic process	ARBA:ARBA00087584	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/JKD	Q700D2	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr	ACCEPT
ARATH/LFY	Q00958	3702	GO:0010074		ARBA:ARBA00091440	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|roo	MODIFY
ARATH/LHP1	Q946J8	3702	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:lhp1_maintenance|vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance|vernalization_flc_silencing:vrn5_adaptor	bacterial_recbcd_end_resection|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|riboflavin_biosynthesis|vesicle_coat_budding	MODIFY
ARATH/LHY	Q6R0H1	3702	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/LYK4	O64825	3702	GO:0045087	innate immune response	ARBA:ARBA00027946	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	ACCEPT
ARATH/LYK4	O64825	3702	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	brassinosteroid_signaling		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase	auxin_polar_transport|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phytochrome_photomorphog	MARK_AS_OVER_ANNOTATED
ARATH/LYK5	O22808	3702	GO:0045087	innate immune response	ARBA:ARBA00027946	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			chitin_perception|heat_shock_response	ACCEPT
ARATH/LYK5	O22808	3702	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	brassinosteroid_signaling|gibberellin_della_signaling|glutathione_dependent_formaldehyde_detoxification|jasmonate_coi1_jaz_signaling|methylglyoxal_detoxification			chitin_perception|heat_shock_response	MARK_AS_OVER_ANNOTATED
ARATH/MAM1	Q9FG67	3702	GO:0019761	glucosinolate biosynthetic process	ARBA:ARBA00085760	ENTAILED	True	aliphatic_glucosinolate_myrosinase_defense		aliphatic_glucosinolate_myrosinase_defense:mam_activity	alginate_o_acetylation|branched_chain_amino_acid_biosynthesis	ACCEPT
ARATH/MAM3	Q9FN52	3702	GO:0019761	glucosinolate biosynthetic process	ARBA:ARBA00085760	ENTAILED	True	aliphatic_glucosinolate_myrosinase_defense		aliphatic_glucosinolate_myrosinase_defense:mam_activity	alginate_o_acetylation|branched_chain_amino_acid_biosynthesis	ACCEPT
ARATH/MAX2	Q9SIM9	3702	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False					MODIFY
ARATH/MAX2	Q9SIM9	3702	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	floral_organ_identity_abce				MARK_AS_OVER_ANNOTATED
ARATH/MAX2	Q9SIM9	3702	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NOT_ENTAILED	False	autonomous_flowering_pathway|shoot_meristem_clv_wus_feedback|strigolactone_signaling_shoot_branching				MODIFY
ARATH/MGP	Q9ZWA6	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/MKK4	O80397	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	brassinosteroid_signaling|chitin_perception|erk5_cascade|ethylene_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|jnk_cascade|mapk_relay|p38_cascade|phytochrome_photomorphogenesis		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|chitin_perception:bik1_kinase|chitin_perception:mkk45_activity|chitin_perception:pbl27_kinase|erk5_cascade:erk5_map2k_activity|ethylene_signaling:ctr1_kinase|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|jnk_cascade:jnk_map2k_activity|mapk_relay:map2k_activity|p38_cascade:p38_map2k_activity|phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|stomatal_lineage_development	ACCEPT
ARATH/MKK4	O80397	3702	GO:0010227	floral organ abscission	ARBA:ARBA00026833	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	KEEP_AS_NON_CORE
ARATH/MKK4	O80397	3702	GO:0010229	inflorescence development	ARBA:ARBA00090608	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	KEEP_AS_NON_CORE
ARATH/MKK4	O80397	3702	GO:0098542	defense response to other organism	ARBA:ARBA00027395	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	ACCEPT
ARATH/MKK5	Q8RXG3	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	brassinosteroid_signaling|chitin_perception|erk5_cascade|ethylene_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|jnk_cascade|mapk_relay|p38_cascade|phytochrome_photomorphogenesis		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|chitin_perception:bik1_kinase|chitin_perception:mkk45_activity|chitin_perception:pbl27_kinase|erk5_cascade:erk5_map2k_activity|ethylene_signaling:ctr1_kinase|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|jnk_cascade:jnk_map2k_activity|mapk_relay:map2k_activity|p38_cascade:p38_map2k_activity|phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|stomatal_lineage_development	ACCEPT
ARATH/MKK5	Q8RXG3	3702	GO:0010227	floral organ abscission	ARBA:ARBA00026833	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	KEEP_AS_NON_CORE
ARATH/MKK5	Q8RXG3	3702	GO:0010229	inflorescence development	ARBA:ARBA00090608	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	KEEP_AS_NON_CORE
ARATH/MKK5	Q8RXG3	3702	GO:0098542	defense response to other organism	ARBA:ARBA00027395	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and	ACCEPT
ARATH/MPK3	Q39023	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	brassinosteroid_signaling|chitin_perception|erk5_cascade|ethylene_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|jnk_cascade|mapk_relay|p38_cascade|phytochrome_photomorphogenesis		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|chitin_perception:bik1_kinase|chitin_perception:mpk36_activity|chitin_perception:pbl27_kinase|erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|ethylene_signaling:ctr1_kinase|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output|phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|camalexin_biosynthesis|coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|stomatal_lineage_development	ACCEPT
ARATH/MPK3	Q39023	3702	GO:0160109	plant gross anatomical part developmental process	ARBA:ARBA00098140	ENTAILED	False	stomatal_lineage_development		stomatal_lineage_development:mpk6_mapk	auxin_polar_transport|brassinosteroid_signaling|camalexin_biosynthesis|chitin_perception|coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_	KEEP_AS_NON_CORE
ARATH/MPK6	Q39026	3702	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	brassinosteroid_signaling|chitin_perception|erk5_cascade|ethylene_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|jnk_cascade|mapk_relay|p38_cascade|phytochrome_photomorphogenesis		brassinosteroid_signaling:bin2_gsk3|brassinosteroid_signaling:bri1_receptor|brassinosteroid_signaling:bsk1_relay_kinase|chitin_perception:bik1_kinase|chitin_perception:mpk36_activity|chitin_perception:pbl27_kinase|erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|ethylene_signaling:ctr1_kinase|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output|phytochrome_photomorphogenesis:spa1_pif1_kinase	auxin_polar_transport|camalexin_biosynthesis|coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|stomatal_lineage_development	ACCEPT
ARATH/MYB122	Q9C9C8	3702	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_	KEEP_AS_NON_CORE
ARATH/MYB122	Q9C9C8	3702	GO:0051707	response to other organism	ARBA:ARBA00029118	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling			auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/MYB34	O64399	3702	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_	KEEP_AS_NON_CORE
ARATH/MYB34	O64399	3702	GO:0051707	response to other organism	ARBA:ARBA00029118	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling			auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/MYC2	Q39204	3702	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	MODIFY
ARATH/NPR1	P93002	3702	GO:0031347	regulation of defense response	ARBA:ARBA00028262	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling			gibberellin_della_signaling|root_radial_patterning_shr_scr|trichome_initiation_mbw	ACCEPT
ARATH/NPR1	P93002	3702	GO:0045087	innate immune response	ARBA:ARBA00027946	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			gibberellin_della_signaling|root_radial_patterning_shr_scr|trichome_initiation_mbw	ACCEPT
ARATH/NSP1	Q9SDM9	3702	GO:0009845	seed germination	ARBA:ARBA00084883	NO_MODULE	False				autonomous_flowering_pathway|sphingolipid_de_novo_synthesis	UNDECIDED
ARATH/OST1	Q940H6	3702	GO:0009414	response to water deprivation	ARBA:ARBA00028094	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	ACCEPT
ARATH/OST1	Q940H6	3702	GO:0009651	response to salt stress	ARBA:ARBA00026582	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	KEEP_AS_NON_CORE
ARATH/OST1	Q940H6	3702	GO:0009737	response to abscisic acid	ARBA:ARBA00033526	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|pe	ACCEPT
ARATH/PAL1	P35510	3702	GO:0006952	defense response	ARBA:ARBA00026315	NOT_ENTAILED	False	plant_nlr_resistosome_signaling				KEEP_AS_NON_CORE
ARATH/PAL1	P35510	3702	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	NO_MODULE	False					KEEP_AS_NON_CORE
ARATH/PAL1	P35510	3702	GO:0009611	response to wounding	ARBA:ARBA00026469	NO_MODULE	False					KEEP_AS_NON_CORE
ARATH/PAL1	P35510	3702	GO:0009698	phenylpropanoid metabolic process	ARBA:ARBA00026696	NO_MODULE	False					ACCEPT
ARATH/PAL1	P35510	3702	GO:0046395	carboxylic acid catabolic process	ARBA:ARBA00027882	NOT_ENTAILED	False	arginine_catabolism_arginase_pathway|aspartate_asparagine_metabolism|branched_chain_amino_acid_catabolism|fatty_acid_beta_oxidation|glucarate_galactarate_catabolism				MARK_AS_OVER_ANNOTATED
ARATH/PDS	Q07356	3702	GO:0016120	carotene biosynthetic process	ARBA:ARBA00028053	ENTAILED	True	carotene_backbone_biosynthesis		carotene_backbone_biosynthesis:crti_activity|carotene_backbone_biosynthesis:pds_activity	complex_i_assembly_factors	ACCEPT
ARATH/PI	P48007	3702	GO:0010093	specification of floral organ identity	ARBA:ARBA00090791	ENTAILED	True	floral_organ_identity_abce		floral_organ_identity_abce:ag_c_class_tf|floral_organ_identity_abce:ap1_a_class_tf|floral_organ_identity_abce:ap2_a_class_repressor|floral_organ_identity_abce:ap3_b_class_tf|floral_organ_identity_abce:carpel_quartet_tf|floral_organ_identity_abce:petal_quartet_tf|floral_organ_identity_abce:pi_b_class_tf|floral_organ_identity_abce:sep1_e_class|floral_organ_identity_abce:sep2_e_class|floral_organ_identity_abce:sep3_e_class_hub|floral_organ_identity_abce:sep4_e_class|floral_organ_identity_abce:sepal_quartet_tf|floral_organ_identity_abce:stamen_quartet_tf	autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_ci	ACCEPT
ARATH/PID	O64682	3702	GO:0048825	cotyledon development	ARBA:ARBA00090556	NO_MODULE	False				auxin_polar_transport|brassinosteroid_signaling|chitin_perception|coenzyme_a_biosynthesis|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recyclin	KEEP_AS_NON_CORE
ARATH/PIF1	Q8GZM7	3702	GO:0010017	red or far-red light signaling pathway	ARBA:ARBA00044396	ENTAILED	True	phytochrome_photomorphogenesis		phytochrome_photomorphogenesis:hy5_transcription_factor|phytochrome_photomorphogenesis:pif1_transcription_factor|phytochrome_photomorphogenesis:pif3_transcription_factor|phytochrome_photomorphogenesis:pif4_transcription_factor	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|sho	ACCEPT
ARATH/PIF3	O80536	3702	GO:0010017	red or far-red light signaling pathway	ARBA:ARBA00044396	ENTAILED	True	phytochrome_photomorphogenesis		phytochrome_photomorphogenesis:hy5_transcription_factor|phytochrome_photomorphogenesis:pif1_transcription_factor|phytochrome_photomorphogenesis:pif3_transcription_factor|phytochrome_photomorphogenesis:pif4_transcription_factor	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|sho	ACCEPT
ARATH/PIF4	Q8W2F3	3702	GO:0010017	red or far-red light signaling pathway	ARBA:ARBA00044396	ENTAILED	True	phytochrome_photomorphogenesis		phytochrome_photomorphogenesis:hy5_transcription_factor|phytochrome_photomorphogenesis:pif1_transcription_factor|phytochrome_photomorphogenesis:pif3_transcription_factor|phytochrome_photomorphogenesis:pif4_transcription_factor	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_linea	ACCEPT
ARATH/PIN1	Q9C6B8	3702	GO:0060918	auxin transport	ARBA:ARBA00026839	ENTAILED	False	auxin_polar_transport		auxin_polar_transport:abcb19_auxin_export|auxin_polar_transport:pin1_efflux|auxin_polar_transport:pin2_efflux	heat_shock_response	ACCEPT
ARATH/PIN2	Q9LU77	3702	GO:0060918	auxin transport	ARBA:ARBA00026839	ENTAILED	False	auxin_polar_transport		auxin_polar_transport:abcb19_auxin_export|auxin_polar_transport:pin1_efflux|auxin_polar_transport:pin2_efflux	heat_shock_response	ACCEPT
ARATH/PRR5	Q6LA42	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	ENTAILED	True	plant_circadian_clock_oscillator		plant_circadian_clock_oscillator:cca1_myb_tf|plant_circadian_clock_oscillator:lhy_myb_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage	ACCEPT
ARATH/PRR7	Q93WK5	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	ENTAILED	True	plant_circadian_clock_oscillator		plant_circadian_clock_oscillator:cca1_myb_tf|plant_circadian_clock_oscillator:lhy_myb_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage	ACCEPT
ARATH/PRR9	Q8L500	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	ENTAILED	True	plant_circadian_clock_oscillator		plant_circadian_clock_oscillator:cca1_myb_tf|plant_circadian_clock_oscillator:lhy_myb_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage	ACCEPT
ARATH/PYR1	O49686	3702	GO:0009738	abscisic acid-activated signaling pathway	ARBA:ARBA00085216	NO_MODULE	False				g2_m_transition|heat_shock_response|jasmonate_coi1_jaz_signaling|sphingolipid_de_novo_synthesis|strigolactone_signaling_shoot_branching	ACCEPT
ARATH/RBOHD	Q9FIJ0	3702	GO:0006952	defense response	ARBA:ARBA00026315	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling	ACCEPT
ARATH/RDR6	Q9SG02	3702	GO:0031047	regulatory ncRNA-mediated gene silencing	ARBA:ARBA00027536	NO_MODULE	False				sphingolipid_de_novo_synthesis	ACCEPT
ARATH/RGA	Q9SLH3	3702	GO:0009740	gibberellic acid mediated signaling pathway	ARBA:ARBA00028868	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/RPM1	Q39214	3702	GO:0009626	plant-type hypersensitive response	ARBA:ARBA00091908	NOT_ENTAILED	True	plant_nlr_resistosome_signaling				ACCEPT
ARATH/SEP1	P29382	3702	GO:0048440	carpel development	ARBA:ARBA00089672	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_	KEEP_AS_NON_CORE
ARATH/SEP2	P29384	3702	GO:0048440	carpel development	ARBA:ARBA00089672	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_	KEEP_AS_NON_CORE
ARATH/SEP4	P29383	3702	GO:0048440	carpel development	ARBA:ARBA00089672	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_	KEEP_AS_NON_CORE
ARATH/SMXL8	F4IGZ2	3702	GO:1902347	response to strigolactone	ARBA:ARBA00089248	NOT_ENTAILED	False	strigolactone_signaling_shoot_branching			bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
ARATH/SOC1	O64645	3702	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	ENTAILED	False	shoot_meristem_clv_wus_feedback|strigolactone_signaling_shoot_branching		shoot_meristem_clv_wus_feedback:stm_tf|shoot_meristem_clv_wus_feedback:wus_tf|strigolactone_signaling_shoot_branching:brc1_tcp_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circ	MODIFY
ARATH/SPCH	Q700C7	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|brassinosteroid_signaling|cytokinin_two_component_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_merist	KEEP_AS_NON_CORE
ARATH/SSU3	Q9LYT7	3702	GO:0019761	glucosinolate biosynthetic process	ARBA:ARBA00085760	ENTAILED	True	aliphatic_glucosinolate_myrosinase_defense		aliphatic_glucosinolate_myrosinase_defense:ipmi_activity	branched_chain_amino_acid_biosynthesis|methylcitrate_cycle	ACCEPT
ARATH/STM	Q38874	3702	GO:0009888	tissue development	ARBA:ARBA00028065	NO_MODULE	False				autonomous_flowering_pathway|auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|g1_s_transition|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|photoperiodic_flowerin	MODIFY
ARATH/SUN1	Q9FF75	3702	GO:0006997	nucleus organization	ARBA:ARBA00033484	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SUN1	Q9FF75	3702	GO:0051260	protein homooligomerization	ARBA:ARBA00089314	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	KEEP_AS_NON_CORE
ARATH/SUN1	Q9FF75	3702	GO:0051291	protein heterooligomerization	ARBA:ARBA00089325	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	KEEP_AS_NON_CORE
ARATH/SUN1	Q9FF75	3702	GO:0070197	meiotic attachment of telomere to nuclear envelope	ARBA:ARBA00092228	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SUN1	Q9FF75	3702	GO:0090435	protein localization to nuclear envelope	ARBA:ARBA00088559	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SUN2	Q9SG79	3702	GO:0006997	nucleus organization	ARBA:ARBA00033484	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SUN2	Q9SG79	3702	GO:0051260	protein homooligomerization	ARBA:ARBA00089314	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	KEEP_AS_NON_CORE
ARATH/SUN2	Q9SG79	3702	GO:0051291	protein heterooligomerization	ARBA:ARBA00089325	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	KEEP_AS_NON_CORE
ARATH/SUN2	Q9SG79	3702	GO:0070197	meiotic attachment of telomere to nuclear envelope	ARBA:ARBA00092228	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SUN2	Q9SG79	3702	GO:0090435	protein localization to nuclear envelope	ARBA:ARBA00088559	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|plant_circadian_clock_oscillator|pyruvate_metabolism|vernalization_flc_silencing|vesicle_coat_budd	ACCEPT
ARATH/SWN	Q9ZSM8	3702	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	MODULE_INCOMPLETE	False	autonomous_flowering_pathway	autonomous_flowering_pathway:coolair_proximal_polyadenylation	autonomous_flowering_pathway:fpa_poly_a_site_choice	bacterial_methionine_cycle|methionine_cycle|vernalization_flc_silencing	ACCEPT
ARATH/SWN	Q9ZSM8	3702	GO:0141044	epigenetic programming in the endosperm	ARBA:ARBA00095392	NO_MODULE	False				autonomous_flowering_pathway|bacterial_methionine_cycle|methionine_cycle|vernalization_flc_silencing	KEEP_AS_NON_CORE
ARATH/TOC1	Q9LKL2	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	ENTAILED	True	plant_circadian_clock_oscillator		plant_circadian_clock_oscillator:cca1_myb_tf|plant_circadian_clock_oscillator:lhy_myb_tf	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|root_radial_patterning_shr_scr|shoot_meristem_clv_wus_feedback|stomatal_lineage	ACCEPT
ARATH/TPL	Q94AI7	3702	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				auxin_nuclear_signaling|floral_meristem_identity|g1_s_transition|gibberellin_della_signaling|heat_shock_response|jasmonate_coi1_jaz_signaling|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|strigolactone_signaling_shoot_branching|trichome_initiation_mbw	ACCEPT
ARATH/TRY	Q8GV05	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/TRY	Q8GV05	3702	GO:0010026	trichome differentiation	ARBA:ARBA00091409	ENTAILED	True	trichome_initiation_mbw		trichome_initiation_mbw:egl3_bhlh_bridge|trichome_initiation_mbw:gl1_r2r3_myb_activator	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	KEEP_AS_NON_CORE
ARATH/TRY	Q8GV05	3702	GO:1900032	regulation of trichome patterning	ARBA:ARBA00092511	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	ACCEPT
ARATH/VAL1	Q8W4L5	3702	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|camalexin_biosynthesis|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_	MODIFY
ARATH/VRN1	Q8L3W1	3702	GO:0009409	response to cold	ARBA:ARBA00028088	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:val1_recruiter|vernalization_flc_silencing:vrn1_maintenance	bacterial_recbcd_end_resection|camalexin_biosynthesis	ACCEPT
ARATH/VRN2	Q8W5B1	3702	GO:0006325	chromatin organization	ARBA:ARBA00028060	ENTAILED	False	vernalization_flc_silencing		vernalization_flc_silencing:vrn1_maintenance	auxin_nuclear_signaling|bacterial_recbcd_end_resection|brassinosteroid_signaling|floral_meristem_identity|floral_organ_identity_abce|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|root_radial_patterning_shr_scr|shoot_meristem_	ACCEPT
ARATH/ZTL	Q94BT6	3702	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False				photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	MODIFY
ARATH/ZTL	Q94BT6	3702	GO:0007623	circadian rhythm	ARBA:ARBA00027901	ENTAILED	True	plant_circadian_clock_oscillator		plant_circadian_clock_oscillator:ztl_photoreceptor	photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|strigolactone_signaling_shoot_branching	ACCEPT
ARATH/ZTL	Q94BT6	3702	GO:0009637	response to blue light	ARBA:ARBA00026676	NO_MODULE	False				photoperiodic_flowering_co_ft|phytochrome_photomorphogenesis|plant_circadian_clock_oscillator|strigolactone_signaling_shoot_branching	ACCEPT
BACSU/minD	Q01464	224308	GO:0032506	cytokinetic process	ARBA:ARBA00028734	NOT_ENTAILED	False	bacterial_divisome_peptidoglycan_transpeptidation			bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secretion_apparatus|coenzyme_q10_biosynt	ACCEPT
BRADI/LOC100829928	I1IBL7	15368	GO:0009699	phenylpropanoid biosynthetic process	ARBA:ARBA00026697	NO_MODULE	False					ACCEPT
BURCH/A0B297	A0B297	331272	GO:0015749	monosaccharide transmembrane transport	ARBA:ARBA00028498	NO_MODULE	False				bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_ribose_uptake_and_entry|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secret	ACCEPT
CAEBR/tra-1	Q17308	6238	GO:0019099	female germ-line sex determination	ARBA:ARBA00092111	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	KEEP_AS_NON_CORE
CAEBR/tra-1	Q17308	6238	GO:0019101	female somatic sex determination	ARBA:ARBA00085316	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	KEEP_AS_NON_CORE
CANAL/BCY1	Q9HEW1	237561	GO:0009267	cellular response to starvation	ARBA:ARBA00034565	NO_MODULE	False				heat_shock_response|sphingolipid_de_novo_synthesis	REMOVE
CANAL/CEK1	Q5A1D3	237561	GO:0009272	fungal-type cell wall biogenesis	ARBA:ARBA00033809	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
CANAL/ESA1	Q5A7Q2	237561	GO:0006974	DNA damage response	ARBA:ARBA00026271	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
CANAL/HOG1	Q92207	237561	GO:0000165	MAPK cascade	ARBA:ARBA00029221	ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade		erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
CANAL/HSP104	A0A1D8PTP9	237561	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
CANAL/HSP104	A0A1D8PTP9	237561	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
CANAL/HSP104	A0A1D8PTP9	237561	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
CANAL/HSP78	Q96UX5	237561	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
CAPO3/coWts	A0A0D2VGR4	595528	GO:0007010	cytoskeleton organization	ARBA:ARBA00026736	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
CAPO3/coWts	A0A0D2VGR4	595528	GO:1900181	negative regulation of protein localization to nucleus	ARBA:ARBA00092942	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
COTJA/A0A8C2TBA7	A0A8C2TBA7	93934	GO:0001519	peptide amidation	ARBA:ARBA00093736	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
CRIGR/HSPH1	Q60446	10029	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response|nlrp3_inflammasome		heat_shock_response:bag_nef|heat_shock_response:hsp110_nef|nlrp3_inflammasome:nlrp3_nacht_atp_switch	coenzyme_q10_biosynthesis|linc_complex|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
CUCME/A0A1S3BTE3	A0A1S3BTE3	3656	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	erk5_cascade|ethylene_signaling|gpcr_plc_calcium_pkc_signaling|jnk_cascade|mapk_relay|p38_cascade		erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|ethylene_signaling:ctr1_kinase|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
DANRE/asah2	Q5W7F1	7955	GO:0006672	ceramide metabolic process	ARBA:ARBA00028785	NOT_ENTAILED	False	glycosphingolipid_biosynthesis|sphingolipid_de_novo_synthesis			glycosphingolipid_lysosomal_degradation|gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism|sphingosine_1_phosphate_rheostat	ACCEPT
DANRE/cpt2	Q5U3U3	7955	GO:0015909	long-chain fatty acid transport	ARBA:ARBA00088749	ENTAILED	False	carnitine_shuttle		carnitine_shuttle:cpt1a_activity|carnitine_shuttle:cpt2_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
DANRE/crppa	A0JPF9	7955	GO:0009101	glycoprotein biosynthetic process	ARBA:ARBA00027560	NOT_ENTAILED	False	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|n_glycan_llo_assembly_cytoplasmic|n_glycan_llo_assembly_lumenal|oligosaccharyltransferase_complex			heat_shock_response|sphingolipid_de_novo_synthesis	MODIFY
DANRE/cryabb	A0A8M9Q8E3	7955	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_accessory_subunits|hedgehog_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
DANRE/ctdspl2a	Q08BB5	7955	GO:0045722	positive regulation of gluconeogenesis	ARBA:ARBA00084180	NO_MODULE	False				gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DANRE/ctdspl2b	A4QNX6	7955	GO:0045722	positive regulation of gluconeogenesis	ARBA:ARBA00084180	NO_MODULE	False				gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DANRE/cyp26a1	P79739	7955	GO:0034653	retinoic acid catabolic process	ARBA:ARBA00049846	NO_MODULE	False				complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
DANRE/dla	Q6DI48	7955	GO:0007389	pattern specification process	ARBA:ARBA00027400	NOT_ENTAILED	True	body_axis_specification|hedgehog_signaling|neural_ectoderm_anteroposterior_specification			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/dla	Q6DI48	7955	GO:0021514	ventral spinal cord interneuron differentiation	ARBA:ARBA00084983	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/dla	Q6DI48	7955	GO:0043009	chordate embryonic development	ARBA:ARBA00027425	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/dla	Q6DI48	7955	GO:0048863	stem cell differentiation	ARBA:ARBA00090702	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/dla	Q6DI48	7955	GO:0060485	mesenchyme development	ARBA:ARBA00026415	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	REMOVE
DANRE/fgf8a	O57341	7955	GO:0007498	mesoderm development	ARBA:ARBA00084318	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DANRE/fgf8a	O57341	7955	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	ENTAILED	False	neural_ectoderm_anteroposterior_specification		neural_ectoderm_anteroposterior_specification:fgf_posteriorising_ligand	egfr_signaling|erbb2_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DANRE/fgf8a	O57341	7955	GO:0042664	negative regulation of endodermal cell fate specification	ARBA:ARBA00086809	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DANRE/fgf8b	Q805B2	7955	GO:0007498	mesoderm development	ARBA:ARBA00084318	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/fgf8b	Q805B2	7955	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	ENTAILED	False	neural_ectoderm_anteroposterior_specification		neural_ectoderm_anteroposterior_specification:fgf_posteriorising_ligand	egfr_signaling|erbb2_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/fgf8b	Q805B2	7955	GO:0042664	negative regulation of endodermal cell fate specification	ARBA:ARBA00086809	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|notch_signaling	REMOVE
DANRE/gnptab	Q5RGJ8	7955	GO:0015031	protein transport	ARBA:ARBA00026546	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|sphingolipid_de_novo_synthesis	MODIFY
DANRE/gtpbp3	Q501Z5	7955	GO:0070900	mitochondrial tRNA modification	ARBA:ARBA00086089	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|urease_biogenesis_urea_hy	ACCEPT
DANRE/hif1an	P59723	7955	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response	KEEP_AS_NON_CORE
DANRE/hif1an	P59723	7955	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response	KEEP_AS_NON_CORE
DANRE/hsd17b3	Q6QA32	7955	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	sex_steroid_biosynthesis		sex_steroid_biosynthesis:hsd17b3_activity	complex_i_assembly_factors	MODIFY
DANRE/kita	Q8JFR5	7955	GO:0030318	melanocyte differentiation	ARBA:ARBA00087401	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DANRE/kita	Q8JFR5	7955	GO:0097324	melanocyte migration	ARBA:ARBA00089596	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DANRE/mfsd2aa	Q5U3U7	7955	GO:0051977	lysophospholipid transport	ARBA:ARBA00089921	NO_MODULE	False				ketone_body_oxidation	ACCEPT
DANRE/notch1a	P46530	7955	GO:0007409	axonogenesis	ARBA:ARBA00026520	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0007417	central nervous system development	ARBA:ARBA00026561	NOT_ENTAILED	False	nucleokinesis			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0007422	peripheral nervous system development	ARBA:ARBA00084148	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/notch1a	P46530	7955	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	NOT_ENTAILED	False	neural_ectoderm_anteroposterior_specification			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0010001	glial cell differentiation	ARBA:ARBA00091307	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0031017	exocrine pancreas development	ARBA:ARBA00084589	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0035282	segmentation	ARBA:ARBA00091150	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0042659	regulation of cell fate specification	ARBA:ARBA00086800	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/notch1a	P46530	7955	GO:0048568	embryonic organ development	ARBA:ARBA00029173	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/notch1a	P46530	7955	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	NOT_ENTAILED	False	germ_layer_specification			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
DANRE/notch1a	P46530	7955	GO:0050768	negative regulation of neurogenesis	ARBA:ARBA00089677	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0060218	hematopoietic stem cell differentiation	ARBA:ARBA00091182	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0060429	epithelium development	ARBA:ARBA00027680	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/notch1a	P46530	7955	GO:0072359	circulatory system development	ARBA:ARBA00027039	NOT_ENTAILED	False	cardiac_specification_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
DANRE/pax6a	P26630	7955	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	ENTAILED	False	neural_ectoderm_anteroposterior_specification		neural_ectoderm_anteroposterior_specification:ane_otx2|neural_ectoderm_anteroposterior_specification:fb_foxg1|neural_ectoderm_anteroposterior_specification:fb_six3|neural_ectoderm_anteroposterior_specification:mb_en1|neural_ectoderm_anteroposterior_specification:ne_sox2|neural_ectoderm_anteroposterior_specification:pne_gbx2|neural_ectoderm_anteroposterior_specification:pne_hox_anterior|neural_ectoderm_anteroposterior_specification:r56_hnf1b|neural_ectoderm_anteroposterior_specification:r56_hoxa3|neural_ectoderm_anteroposterior_specification:r56_mafb	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|notch_signaling	KEEP_AS_NON_CORE
DANRE/pax6a	P26630	7955	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_ectoderm_anteroposterior_specification|notch_signaling|nrf_oxidative_stress	KEEP_AS_NON_CORE
DANRE/pax6a	P26630	7955	GO:0030902	hindbrain development	ARBA:ARBA00088342	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	KEEP_AS_NON_CORE
DANRE/pax6a	P26630	7955	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
DANRE/pax6a	P26630	7955	GO:0048593	camera-type eye morphogenesis	ARBA:ARBA00091222	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
DANRE/pax6b	A0A0R4IQL7	7955	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	ENTAILED	False	neural_ectoderm_anteroposterior_specification		neural_ectoderm_anteroposterior_specification:ane_otx2|neural_ectoderm_anteroposterior_specification:fb_foxg1|neural_ectoderm_anteroposterior_specification:fb_six3|neural_ectoderm_anteroposterior_specification:mb_en1|neural_ectoderm_anteroposterior_specification:ne_sox2|neural_ectoderm_anteroposterior_specification:pne_gbx2|neural_ectoderm_anteroposterior_specification:pne_hox_anterior|neural_ectoderm_anteroposterior_specification:r56_hnf1b|neural_ectoderm_anteroposterior_specification:r56_hoxa3|neural_ectoderm_anteroposterior_specification:r56_mafb	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|notch_signaling	KEEP_AS_NON_CORE
DANRE/pax6b	A0A0R4IQL7	7955	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_ectoderm_anteroposterior_specification|notch_signaling|nrf_oxidative_stress	KEEP_AS_NON_CORE
DANRE/pax6b	A0A0R4IQL7	7955	GO:0030902	hindbrain development	ARBA:ARBA00088342	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	KEEP_AS_NON_CORE
DANRE/pax6b	A0A0R4IQL7	7955	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
DANRE/pax6b	A0A0R4IQL7	7955	GO:0048593	camera-type eye morphogenesis	ARBA:ARBA00091222	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
DANRE/polb	Q6DRD3	7955	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	MODULE_INCOMPLETE	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|muth_independent_mismatch_repair	bacterial_nucleotide_excision_repair:liga_sealing|bacterial_recbcd_end_resection:recb_resection|muth_independent_mismatch_repair:repair_synthesis_and_sealing	bacterial_nucleotide_excision_repair:pola_activity|bacterial_nucleotide_excision_repair:uvrc_activity|bacterial_recbcd_end_resection:recc_scaffold_activity|muth_independent_mismatch_repair:dna_polymerase_repair_synthesis	sphingolipid_de_novo_synthesis	MODIFY
DANRE/prmt6	Q6NWG4	7955	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			bacterial_methionine_cycle|methionine_cycle	MODIFY
DANRE/rbpjb	A4FTT4	7955	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial	KEEP_AS_NON_CORE
DANRE/rbpjb	A4FTT4	7955	GO:0007221	positive regulation of transcription of Notch receptor target	ARBA:ARBA00084930	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial	ACCEPT
DANRE/rbpjb	A4FTT4	7955	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial_upr|neural_crest_gene_re	MARK_AS_OVER_ANNOTATED
DANRE/rbpjb	A4FTT4	7955	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial_upr|neural_ectoderm_anteropos	MARK_AS_OVER_ANNOTATED
DANRE/rbpjb	A4FTT4	7955	GO:0060429	epithelium development	ARBA:ARBA00027680	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0007389	pattern specification process	ARBA:ARBA00027400	ENTAILED	True	hedgehog_signaling		hedgehog_signaling:hh_autoprocessing|hedgehog_signaling:hh_cholesterol_transfer	erbb2_signaling|gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0007417	central nervous system development	ARBA:ARBA00026561	NOT_ENTAILED	False	nucleokinesis			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DANRE/shha	Q92008	7955	GO:0030182	neuron differentiation	ARBA:ARBA00027575	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0035295	tube development	ARBA:ARBA00027800	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DANRE/shha	Q92008	7955	GO:0042063	gliogenesis	ARBA:ARBA00086246	NOT_ENTAILED	False	nucleokinesis			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0045165	cell fate commitment	ARBA:ARBA00043601	NOT_ENTAILED	False	cardiac_specification_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/shha	Q92008	7955	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DANRE/shha	Q92008	7955	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DANRE/shha	Q92008	7955	GO:0055002	striated muscle cell development	ARBA:ARBA00084647	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DANRE/smad3a	Q8AY15	7955	GO:0009880	embryonic pattern specification	ARBA:ARBA00084933	ENTAILED	True	body_axis_specification		body_axis_specification:ap_anterior_readout|body_axis_specification:ap_posterior_readout|body_axis_specification:dv_organizer_tf	bacterial_recbcd_end_resection|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm_anteroposterior_specifi	KEEP_AS_NON_CORE
DANRE/smad3a	Q8AY15	7955	GO:0009953	dorsal/ventral pattern formation	ARBA:ARBA00027261	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/smad3a	Q8AY15	7955	GO:0030509	BMP signaling pathway	ARBA:ARBA00086900	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/smad3b	Q8AY16	7955	GO:0009880	embryonic pattern specification	ARBA:ARBA00084933	ENTAILED	True	body_axis_specification		body_axis_specification:ap_anterior_readout|body_axis_specification:ap_posterior_readout|body_axis_specification:dv_organizer_tf	bacterial_recbcd_end_resection|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm_anteroposterior_specifi	KEEP_AS_NON_CORE
DANRE/smad3b	Q8AY16	7955	GO:0009953	dorsal/ventral pattern formation	ARBA:ARBA00027261	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/smad3b	Q8AY16	7955	GO:0030509	BMP signaling pathway	ARBA:ARBA00086900	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/sult1st2	Q7ZUS4	7955	GO:0006805	xenobiotic metabolic process	ARBA:ARBA00087308	NOT_ENTAILED	False	phenylacetate_catabolism				ACCEPT
DANRE/tbx5a	Q9IAK8	7955	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm_anteroposterior_specific	ACCEPT
DANRE/tbx5a	Q9IAK8	7955	GO:0060429	epithelium development	ARBA:ARBA00027680	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/tbx5b	E3W6T6	7955	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm_anteroposterior_specific	ACCEPT
DANRE/tbx5b	E3W6T6	7955	GO:0060429	epithelium development	ARBA:ARBA00027680	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
DANRE/tdp2	Q5XJA0	7955	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			bacterial_recbcd_end_resection|gpi_anchor_remodeling|muth_independent_mismatch_repair|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DANRE/trpm7	Q563W7	7955	GO:0030001	metal ion transport	ARBA:ARBA00028072	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
DANRE/ube2ib	Q9DDJ0	7955	GO:0001947	heart looping	ARBA:ARBA00091286	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
DANRE/ube2ib	Q9DDJ0	7955	GO:0036306	embryonic heart tube elongation	ARBA:ARBA00089896	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
DANRE/ube2ib	Q9DDJ0	7955	GO:0060216	definitive hemopoiesis	ARBA:ARBA00091179	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
DESRO/K9IJK6	K9IJK6	9430	GO:0071396	cellular response to lipid	ARBA:ARBA00027803	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DESRO/K9IJK6	K9IJK6	9430	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|insulin_receptor_signaling|methylglyoxal_detoxification			hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
DESRO/K9IMD0	K9IMD0	9430	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DESRO/K9J287	K9J287	9430	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	MODULE_INCOMPLETE	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection	bacterial_nucleotide_excision_repair:liga_sealing|bacterial_recbcd_end_resection:recb_resection	bacterial_nucleotide_excision_repair:uvrc_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|gpi_anchor_remodeling|phenylacetate_catabolism	MODIFY
DESVH/Q72F05	Q72F05	882	GO:0030001	metal ion transport	ARBA:ARBA00028072	NO_MODULE	False					REMOVE
DICDI/acgA	Q03101	44689	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	gpcr_camp_pka_signaling		gpcr_camp_pka_signaling:adenylyl_cyclase	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|heat_shock_response|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/carA	P13773	44689	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	dicty_jak_independent_stat_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling		dicty_jak_independent_stat_signaling:car1_receptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|dicty_starvation_initiation|dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/carB	P34907	44689	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	dicty_jak_independent_stat_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling		dicty_jak_independent_stat_signaling:car1_receptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/carC	P35352	44689	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	dicty_jak_independent_stat_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch		dicty_jak_independent_stat_signaling:car1_receptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|gtpase_switch:gap_activity	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/carD	Q9TX43	44689	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	dicty_jak_independent_stat_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling		dicty_jak_independent_stat_signaling:car1_receptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis	ACCEPT
DICDI/cotB	P15269	44689	GO:0030435	sporulation resulting in formation of a cellular spore	ARBA:ARBA00028005	NOT_ENTAILED	True	dicty_sdf2_encapsulation_relay			bacterial_recbcd_end_resection	ACCEPT
DICDI/gpaB	P16051	44689	GO:0007010	cytoskeleton organization	ARBA:ARBA00026736	NO_MODULE	False				chylomicron_assembly_secretion|complex_i_assembly_factors|dicty_counting_factor_size_control|dicty_extracellular_camp_relay|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|propionyl_coa_catabo	KEEP_AS_NON_CORE
DICDI/mhcA	P08799	44689	GO:0031152	aggregation involved in sorocarp development	ARBA:ARBA00084367	ENTAILED	True	dicty_allorecognition_adhesion		dicty_allorecognition_adhesion:cada_activity	complex_i_assembly_factors|heat_shock_response|methylcitrate_cycle|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DICDI/mhcA	P08799	44689	GO:0031270	pseudopodium retraction	ARBA:ARBA00086565	NO_MODULE	False				complex_i_assembly_factors|dicty_allorecognition_adhesion|heat_shock_response|methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
DICDI/mhcA	P08799	44689	GO:0048870	cell motility	ARBA:ARBA00026978	NO_MODULE	False				complex_i_assembly_factors|dicty_allorecognition_adhesion|heat_shock_response|methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/phg2	Q54QQ1	44689	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	dicty_sdf2_encapsulation_relay			coenzyme_a_biosynthesis|dicty_jak_independent_stat_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	REMOVE
DICDI/phg2	Q54QQ1	44689	GO:0009967	positive regulation of signal transduction	ARBA:ARBA00027202	NO_MODULE	False				coenzyme_a_biosynthesis|dicty_jak_independent_stat_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/pkaC	P34099	44689	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	dicty_sdf2_encapsulation_relay		dicty_sdf2_encapsulation_relay:pkac_activity	coenzyme_a_biosynthesis|dicty_jak_independent_stat_signaling|dicty_starvation_initiation|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_no	KEEP_AS_NON_CORE
DICDI/pkaR	P05987	44689	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NO_MODULE	False				dicty_sdf2_encapsulation_relay|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/pkaR	P05987	44689	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				dicty_sdf2_encapsulation_relay|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0031038	myosin II filament organization	ARBA:ARBA00093689	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0031152	aggregation involved in sorocarp development	ARBA:ARBA00084367	NOT_ENTAILED	True	dicty_allorecognition_adhesion|dicty_extracellular_camp_relay|dicty_starvation_initiation			dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0046580	negative regulation of Ras protein signal transduction	ARBA:ARBA00092486	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NOT_ENTAILED	False	dicty_counting_factor_size_control			dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0051489	regulation of filopodium assembly	ARBA:ARBA00088918	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:0051898	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089770	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
DICDI/pten	Q8T9S7	44689	GO:0140986	G protein-coupled chemorepellent receptor signaling pathway	ARBA:ARBA00087020	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/pten	Q8T9S7	44689	GO:1903665	negative regulation of asexual reproduction	ARBA:ARBA00089236	NO_MODULE	False				dicty_jak_independent_stat_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DICDI/statA	O00910	44689	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				bacterial_recbcd_end_resection|dicty_allorecognition_adhesion|dicty_dif1_response_prestalk_patterning|dicty_jak_independent_stat_signaling|g1_s_transition|heat_shock_response	ACCEPT
DICDI/statC	Q54BD4	44689	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				bacterial_recbcd_end_resection|dicty_allorecognition_adhesion|dicty_dif1_response_prestalk_patterning|dicty_jak_independent_stat_signaling|g1_s_transition|heat_shock_response	ACCEPT
DICDI/stlB	Q54FI3	44689	GO:0044550	secondary metabolite biosynthetic process	ARBA:ARBA00029064	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_unsaturated_fatty_acid_biosynthesis|complex_i_assembly_factors|dicty_dif1_biosynthesis|type_ii_fatty_acid_synthesis	ACCEPT
DICDI/tagC	Q23868	44689	GO:0030154	cell differentiation	ARBA:ARBA00027429	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|dicty_sdf2_encapsulation_relay|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DORPE/AP180	Q9U6M6	1051067	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	NOT_ENTAILED	True	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis			synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
DORPE/AP180	Q9U6M6	1051067	GO:0040011	locomotion	ARBA:ARBA00026452	NO_MODULE	False				synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	REMOVE
DORPE/AP180	Q9U6M6	1051067	GO:0048488	synaptic vesicle endocytosis	ARBA:ARBA00091614	MODULE_INCOMPLETE	True	synaptic_vesicle_endocytosis	synaptic_vesicle_endocytosis:adaptor_and_coat_assembly|synaptic_vesicle_endocytosis:coat_disassembly	synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:auxilin_cochaperone|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	synaptic_vesicle_exocytosis	ACCEPT
DORPE/P21613	P21613	1051067	GO:0007097	nuclear migration	ARBA:ARBA00026920	MODULE_INCOMPLETE	True	nucleokinesis	nucleokinesis:nuclear_envelope_motor_coupling|nucleokinesis:dynein_lis1_nude_motor	nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone|hedgehog_signaling|methylcitrate_cycle|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DORPE/P21613	P21613	1051067	GO:0007292	female gamete generation	ARBA:ARBA00028339	NO_MODULE	False				ciliary_transition_zone|hedgehog_signaling|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DORPE/P21613	P21613	1051067	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	ARBA:ARBA00087868	NO_MODULE	False				ciliary_transition_zone|hedgehog_signaling|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DORPE/P21613	P21613	1051067	GO:0048489	synaptic vesicle transport	ARBA:ARBA00091615	NO_MODULE	False				ciliary_transition_zone|hedgehog_signaling|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	ACCEPT
DORPE/P21613	P21613	1051067	GO:0098957	anterograde axonal transport of mitochondrion	ARBA:ARBA00090823	NO_MODULE	False				ciliary_transition_zone|hedgehog_signaling|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	MODIFY
DORPE/TDO	A0A7G4RN94	1051067	GO:0006569	L-tryptophan catabolic process	ARBA:ARBA00026552	MODULE_INCOMPLETE	True	kynurenine_nad_de_novo	kynurenine_nad_de_novo:trp_to_kynurenine|kynurenine_nad_de_novo:kynurenine_to_3haa|kynurenine_nad_de_novo:three_haa_to_nad	kynurenine_nad_de_novo:tdo2_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
DROME/18w	A1ZBR2	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			notch_signaling	ACCEPT
DROME/18w	A1ZBR2	7227	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				notch_signaling	KEEP_AS_NON_CORE
DROME/AGO3	Q7PLK0	7227	GO:0140965	secondary piRNA processing	ARBA:ARBA00087010	NO_MODULE	False				er_unfolded_protein_response|gpi_anchor_remodeling|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/AGO3	Q7PLK0	7227	GO:0141009	transposable element silencing by piRNA-mediated mRNA destabilization	ARBA:ARBA00092222	NO_MODULE	False				er_unfolded_protein_response|gpi_anchor_remodeling|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/AMPKalpha	O18645	7227	GO:0043050	nematode pharyngeal pumping	ARBA:ARBA00084835	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	REMOVE
DROME/Acaa	Q9VL70	7227	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	fatty_acid_beta_oxidation|ketogenesis|ketone_body_oxidation|mevalonate_pathway|peroxisomal_beta_oxidation		fatty_acid_beta_oxidation:lc_thiolase_activity|fatty_acid_beta_oxidation:med_thiolase_activity|fatty_acid_beta_oxidation:sc_thiolase_activity|ketogenesis:acat1_activity|ketone_body_oxidation:thiolase_activity|mevalonate_pathway:thiolase_activity|peroxisomal_beta_oxidation:acaa1_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
DROME/Acadvl	A1ZBJ2	7227	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	fatty_acid_beta_oxidation		fatty_acid_beta_oxidation:vlcad_activity	complex_i_assembly_factors	KEEP_AS_NON_CORE
DROME/Akt1	Q8INB9	7227	GO:0008286	insulin receptor signaling pathway	ARBA:ARBA00092359	ENTAILED	True	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome	ACCEPT
DROME/Akt1	Q8INB9	7227	GO:0008582	regulation of synaptic assembly at neuromuscular junction	ARBA:ARBA00085089	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	UNDECIDED
DROME/Ass	O97069	7227	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	MODULE_INCOMPLETE	False	arginine_biosynthesis	arginine_biosynthesis:glutamate_acetylation_step|arginine_biosynthesis:acetylglutamate_kinase_step|arginine_biosynthesis:acetylglutamyl_phosphate_reductase_step|arginine_biosynthesis:acetylornithine_aminotransferase_step|arginine_biosynthesis:ornithine_release_step|arginine_biosynthesis:ornithine_carbamoyltransferase_step	arginine_biosynthesis:argG_activity	urea_cycle	MODIFY
DROME/CG3515	Q9VQD1	7227	GO:0016070	RNA metabolic process	ARBA:ARBA00028985	NO_MODULE	False					UNDECIDED
DROME/CG42331	Q9VC41	7227	GO:0003006	developmental process involved in reproduction	ARBA:ARBA00026397	NOT_ENTAILED	False	primordial_germ_cell_specification			complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	PENDING
DROME/CG42331	Q9VC41	7227	GO:0022412	cellular process involved in reproduction in multicellular organism	ARBA:ARBA00028215	NOT_ENTAILED	False	primordial_germ_cell_specification			complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	PENDING
DROME/CG42331	Q9VC41	7227	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	NOT_ENTAILED	False	germ_layer_specification			complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	PENDING
DROME/CG43742	A0A0B4KFF2	7227	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	hedgehog_signaling|phenylacetate_catabolism	UNDECIDED
DROME/CG4610	Q9W245	7227	GO:0070899	mitochondrial tRNA wobble uridine modification	ARBA:ARBA00086587	NO_MODULE	False					ACCEPT
DROME/CG4704	Q9VCT5	7227	GO:0036444	calcium import into the mitochondrion	ARBA:ARBA00045049	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
DROME/CG6051	Q9VB70	7227	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	ciliary_transition_zone|kinase_phosphatase_toggle|mitophagy|peptidoglycan_recycling|phagosome_maturation|phenylacetate_catabolism	REMOVE
DROME/CG6051	Q9VB70	7227	GO:0046856	phosphatidylinositol dephosphorylation	ARBA:ARBA00028324	NO_MODULE	False				ciliary_transition_zone|gpi_anchor_remodeling|kinase_phosphatase_toggle|mitophagy|peptidoglycan_recycling|phagosome_maturation|phenylacetate_catabolism	REMOVE
DROME/CG6051	Q9VB70	7227	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				ciliary_transition_zone|gpi_anchor_remodeling|kinase_phosphatase_toggle|mitophagy|peptidoglycan_recycling|phagosome_maturation|phenylacetate_catabolism	REMOVE
DROME/CG8142	Q9VX15	7227	GO:0000076	DNA replication checkpoint signaling	ARBA:ARBA00090203	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
DROME/CG8142	Q9VX15	7227	GO:0006271	DNA strand elongation involved in DNA replication	ARBA:ARBA00028969	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
DROME/CG8142	Q9VX15	7227	GO:0006281	DNA repair	ARBA:ARBA00029008	MODULE_INCOMPLETE	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|muth_independent_mismatch_repair	bacterial_nucleotide_excision_repair:liga_sealing|bacterial_recbcd_end_resection:recb_resection|muth_independent_mismatch_repair:repair_synthesis_and_sealing	bacterial_nucleotide_excision_repair:uvrb_activity|bacterial_recbcd_end_resection:recc_scaffold_activity|muth_independent_mismatch_repair:mutl_atpase	coenzyme_q10_biosynthesis|linc_complex|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
DROME/CG8353	Q9VLR2	7227	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism	pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis	pyrimidine_nucleotide_catabolism:cda_activity	heat_shock_response|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/CG8353	Q9VLR2	7227	GO:0072527	pyrimidine-containing compound metabolic process	ARBA:ARBA00026859	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism	pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis	pyrimidine_nucleotide_catabolism:cda_activity	heat_shock_response|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/CG8353	Q9VLR2	7227	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			heat_shock_response|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism	KEEP_AS_NON_CORE
DROME/CRY	O77059	7227	GO:0009416	response to light stimulus	ARBA:ARBA00028128	NO_MODULE	False				bacterial_recbcd_end_resection	ACCEPT
DROME/Ctns	Q9VCR7	7227	GO:1904919	L-cystine transmembrane transport from lysosomal lumen to cytosol	ARBA:ARBA00098245	NO_MODULE	False					ACCEPT
DROME/Cul1	Q24311	7227	GO:0000209	protein polyubiquitination	ARBA:ARBA00044436	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
DROME/Cul1	Q24311	7227	GO:0010564	regulation of cell cycle process	ARBA:ARBA00027431	NOT_ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
DROME/Cul1	Q24311	7227	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MODIFY
DROME/Cul1	Q24311	7227	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
DROME/Cul1	Q24311	7227	GO:1902532	negative regulation of intracellular signal transduction	ARBA:ARBA00027125	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
DROME/Cul2	Q9V9R2	7227	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MODIFY
DROME/CycA	M9NFR3	7227	GO:0000278	mitotic cell cycle	ARBA:ARBA00028458	NOT_ENTAILED	True	cell_cycle_progression|g1_s_transition|g2_m_transition|metaphase_anaphase_transition_and_mitotic_exit				ACCEPT
DROME/CycA	M9NFR3	7227	GO:0051301	cell division	ARBA:ARBA00027793	NO_MODULE	False					ACCEPT
DROME/Dark	Q7KLI1	7227	GO:0006915	apoptotic process	ARBA:ARBA00027755	NO_MODULE	False				complex_i_accessory_subunits|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MODIFY
DROME/Dark	Q7KLI1	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MARK_AS_OVER_ANNOTATED
DROME/Dcp-1	O02002	7227	GO:0016322	neuron remodeling	ARBA:ARBA00086716	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	UNDECIDED
DROME/Dcp-1	O02002	7227	GO:0045476	nurse cell apoptotic process	ARBA:ARBA00043473	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/Dcp-1	O02002	7227	GO:0045751	negative regulation of Toll signaling pathway	ARBA:ARBA00084359	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/Dcp-1	O02002	7227	GO:0097194	execution phase of apoptosis	ARBA:ARBA00090101	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/Diap1	Q24306	7227	GO:0022416	chaeta development	ARBA:ARBA00092651	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
DROME/Diap1	Q24306	7227	GO:0070936	protein K48-linked ubiquitination	ARBA:ARBA00086253	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
DROME/Diap2	Q24307	7227	GO:0022416	chaeta development	ARBA:ARBA00092651	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/Diap2	Q24307	7227	GO:0070936	protein K48-linked ubiquitination	ARBA:ARBA00086253	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	UNDECIDED
DROME/Dif	P98149	7227	GO:0002225	positive regulation of antimicrobial peptide production	ARBA:ARBA00087827	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/Dif	P98149	7227	GO:0007249	canonical NF-kappaB signal transduction	ARBA:ARBA00085080	NOT_ENTAILED	True	nfkb_canonical_signaling			bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/Dif	P98149	7227	GO:0008063	Toll signaling pathway	ARBA:ARBA00093120	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/Dif	P98149	7227	GO:0035206	regulation of hemocyte proliferation	ARBA:ARBA00091713	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/Dif	P98149	7227	GO:0045087	innate immune response	ARBA:ARBA00027946	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/Dif	P98149	7227	GO:0048935	peripheral nervous system neuron development	ARBA:ARBA00092968	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0000902	cell morphogenesis	ARBA:ARBA00028811	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0007498	mesoderm development	ARBA:ARBA00084318	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0008587	imaginal disc-derived wing margin morphogenesis	ARBA:ARBA00085082	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0016330	second mitotic wave involved in compound eye morphogenesis	ARBA:ARBA00086657	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0030718	germ-line stem cell population maintenance	ARBA:ARBA00088373	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0035214	eye-antennal disc development	ARBA:ARBA00091693	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0036011	imaginal disc-derived leg segmentation	ARBA:ARBA00090233	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0042063	gliogenesis	ARBA:ARBA00086246	NOT_ENTAILED	False	nucleokinesis			egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0046331	lateral inhibition	ARBA:ARBA00093161	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	ACCEPT
DROME/Dl	P10041	7227	GO:0048100	wing disc anterior/posterior pattern formation	ARBA:ARBA00089998	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	NOT_ENTAILED	False	germ_layer_specification			egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0048863	stem cell differentiation	ARBA:ARBA00090702	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Dl	P10041	7227	GO:0060429	epithelium development	ARBA:ARBA00027680	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Doc1	Q9U8L5	7227	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/Doc1	Q9U8L5	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specification|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/DrICE	O01382	7227	GO:0016322	neuron remodeling	ARBA:ARBA00086716	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	UNDECIDED
DROME/DrICE	O01382	7227	GO:0045476	nurse cell apoptotic process	ARBA:ARBA00043473	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/DrICE	O01382	7227	GO:0045751	negative regulation of Toll signaling pathway	ARBA:ARBA00084359	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/DrICE	O01382	7227	GO:0097194	execution phase of apoptosis	ARBA:ARBA00090101	NO_MODULE	False				hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/Dscam1	Q0E9H9	7227	GO:0048812	neuron projection morphogenesis	ARBA:ARBA00026689	NO_MODULE	False				heat_shock_response|notch_signaling	ACCEPT
DROME/Egfr	P04412	7227	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
DROME/Egfr	P04412	7227	GO:0038127	ERBB signaling pathway	ARBA:ARBA00034175	ENTAILED	False	egfr_signaling		egfr_signaling:erbb2_coreceptor_kinase|egfr_signaling:fly_egfr_receptor|egfr_signaling:human_egfr_receptor|egfr_signaling:worm_let23_receptor	coenzyme_a_biosynthesis|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
DROME/Egfr	P04412	7227	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DROME/Egm	Q5U117	7227	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	fatty_acid_beta_oxidation		fatty_acid_beta_oxidation:mcad_activity|fatty_acid_beta_oxidation:vlcad_activity	ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitme	KEEP_AS_NON_CORE
DROME/Elba1	Q9VR17	7227	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			bacterial_recbcd_end_resection|g1_s_transition|notch_signaling|retinal_determination_network	MODIFY
DROME/Elba2	Q9VQD6	7227	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			bacterial_recbcd_end_resection|g1_s_transition|notch_signaling|retinal_determination_network	MODIFY
DROME/Hsp22	P02515	7227	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_6_shsp|heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp23	P02516	7227	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp23	P02516	7227	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				cct_chaperonin_folding|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp26	P02517	7227	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp26	P02517	7227	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				cct_chaperonin_folding|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp27	P02518	7227	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
DROME/Hsp27	P02518	7227	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				cct_chaperonin_folding|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	KEEP_AS_NON_CORE
DROME/HtrA2	Q9VFJ3	7227	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	NOT_ENTAILED	False	complex_i_assembly_factors|complex_iv_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii			hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/HtrA2	Q9VFJ3	7227	GO:0012501	programmed cell death	ARBA:ARBA00028943	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/HtrA2	Q9VFJ3	7227	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/Hus1-like	Q9VN60	7227	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair				MODIFY
DROME/IKKepsilon	Q9V3Y8	7227	GO:0009967	positive regulation of signal transduction	ARBA:ARBA00027202	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
DROME/IKKepsilon	Q9V3Y8	7227	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
DROME/IKKepsilon	Q9V3Y8	7227	GO:0045089	positive regulation of innate immune response	ARBA:ARBA00034392	ENTAILED	False	cgas_sting_signaling|nlr_signaling|toll_like_receptor_signaling		cgas_sting_signaling:tbk1_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase	coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	ACCEPT
DROME/Kpc1	Q9VFC4	7227	GO:0016567	protein ubiquitination	ARBA:ARBA00027966	ENTAILED	True	ubiquitin_transfer_relay		ubiquitin_transfer_relay:e3_activity	alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|wnt_signaling	ACCEPT
DROME/Kpc1	Q9VFC4	7227	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
DROME/Lis-1	Q7KNS3	7227	GO:0051225	spindle assembly	ARBA:ARBA00089339	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
DROME/Lis-1	Q7KNS3	7227	GO:0051299	centrosome separation	ARBA:ARBA00089326	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
DROME/Lsp1alpha	P11995	7227	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False					KEEP_AS_NON_CORE
DROME/Lsp1beta	P11996	7227	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False					KEEP_AS_NON_CORE
DROME/Lsp1gamma	P11997	7227	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False					KEEP_AS_NON_CORE
DROME/Lsp2	Q24388	7227	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False					KEEP_AS_NON_CORE
DROME/Lst8	Q9W328	7227	GO:0032535	regulation of cellular component size	ARBA:ARBA00028855	NO_MODULE	False					MODIFY
DROME/Lst8	Q9W328	7227	GO:0038203	TORC2 signaling	ARBA:ARBA00089220	NO_MODULE	False					ACCEPT
DROME/Lst8	Q9W328	7227	GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089771	NO_MODULE	False					ACCEPT
DROME/MCU	Q8IQ70	7227	GO:0036444	calcium import into the mitochondrion	ARBA:ARBA00045049	NO_MODULE	False					ACCEPT
DROME/MICU1	A2VEI2	7227	GO:0036444	calcium import into the mitochondrion	ARBA:ARBA00045049	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
DROME/MICU3	A0A0B4KHF1	7227	GO:0036444	calcium import into the mitochondrion	ARBA:ARBA00045049	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
DROME/Mef2	P40791	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_signaling|nrf_oxidative_stress_re	ACCEPT
DROME/Mef2	P40791	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_signaling|nrf_oxidative_stress_re	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0001708	cell fate specification	ARBA:ARBA00089615	NOT_ENTAILED	False	cardiac_specification_network			gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0002164	larval development	ARBA:ARBA00043484	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007411	axon guidance	ARBA:ARBA00026528	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007422	peripheral nervous system development	ARBA:ARBA00084148	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007424	open tracheal system development	ARBA:ARBA00084149	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007476	imaginal disc-derived wing morphogenesis	ARBA:ARBA00084208	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007498	mesoderm development	ARBA:ARBA00084318	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0007548	sex differentiation	ARBA:ARBA00028749	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0008347	glial cell migration	ARBA:ARBA00092002	NOT_ENTAILED	False	nucleokinesis			gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0009953	dorsal/ventral pattern formation	ARBA:ARBA00027261	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0010001	glial cell differentiation	ARBA:ARBA00091307	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0010160	formation of animal organ boundary	ARBA:ARBA00090996	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0010631	epithelial cell migration	ARBA:ARBA00091862	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0016318	ommatidial rotation	ARBA:ARBA00086689	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0022407	regulation of cell-cell adhesion	ARBA:ARBA00028251	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0030097	hemopoiesis	ARBA:ARBA00028409	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0030855	epithelial cell differentiation	ARBA:ARBA00027967	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0035222	wing disc pattern formation	ARBA:ARBA00091788	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0035239	tube morphogenesis	ARBA:ARBA00091780	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0035282	segmentation	ARBA:ARBA00091150	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0040008	regulation of growth	ARBA:ARBA00026674	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0042659	regulation of cell fate specification	ARBA:ARBA00086800	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
DROME/N	P07207	7227	GO:0048056	R3/R4 cell differentiation	ARBA:ARBA00043632	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048565	digestive tract development	ARBA:ARBA00091747	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048568	embryonic organ development	ARBA:ARBA00029173	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048598	embryonic morphogenesis	ARBA:ARBA00043386	NOT_ENTAILED	False	germ_layer_specification			gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048608	reproductive structure development	ARBA:ARBA00028277	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048663	neuron fate commitment	ARBA:ARBA00043411	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048732	gland development	ARBA:ARBA00043366	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0048863	stem cell differentiation	ARBA:ARBA00090702	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0050768	negative regulation of neurogenesis	ARBA:ARBA00089677	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0050769	positive regulation of neurogenesis	ARBA:ARBA00089675	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/N	P07207	7227	GO:0120035	regulation of plasma membrane bounded cell projection organization	ARBA:ARBA00028050	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
DROME/Nmnat	Q9VC03	7227	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity|nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_namn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	sphingolipid_de_novo_synthesis	ACCEPT
DROME/Nprl2	Q9VXA0	7227	GO:1904262	negative regulation of TORC1 signaling	ARBA:ARBA00026776	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|gtpase_switch|sphingolipid_de_novo_synthesis	ACCEPT
DROME/P28159	P28159	7227	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/P28159	P28159	7227	GO:0007219	Notch signaling pathway	ARBA:ARBA00028179	ENTAILED	True	notch_signaling		notch_signaling:csl_factor|notch_signaling:hes_repressor|notch_signaling:hey_repressor	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|nrf_oxida	ACCEPT
DROME/P28159	P28159	7227	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_signaling|nrf_oxidative_stress_re	KEEP_AS_NON_CORE
DROME/Pcf11	C0P8M6	7227	GO:0010467	gene expression	ARBA:ARBA00028330	NOT_ENTAILED	False	cct_chaperonin_folding|endogenous_protein_lipoylation|gpi_anchor_core_glycan_assembly|gpi_anchor_ethanolamine_phosphate|gpi_anchor_glcnac_transferase			early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	UNDECIDED
DROME/Pde4	Q9W4S9	7227	GO:0001661	conditioned taste aversion	ARBA:ARBA00089914	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pde4	Q9W4S9	7227	GO:0007268	chemical synaptic transmission	ARBA:ARBA00028185	NOT_ENTAILED	False	synaptic_vesicle_exocytosis			gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
DROME/Pde4	Q9W4S9	7227	GO:0007614	short-term memory	ARBA:ARBA00086035	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pde4	Q9W4S9	7227	GO:0007615	anesthesia-resistant memory	ARBA:ARBA00086036	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pde4	Q9W4S9	7227	GO:0007619	courtship behavior	ARBA:ARBA00044433	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	UNDECIDED
DROME/Pde4	Q9W4S9	7227	GO:0007623	circadian rhythm	ARBA:ARBA00027901	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	UNDECIDED
DROME/Pde4	Q9W4S9	7227	GO:0008355	olfactory learning	ARBA:ARBA00091941	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pde4	Q9W4S9	7227	GO:0040040	thermosensory behavior	ARBA:ARBA00086785	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pde4	Q9W4S9	7227	GO:0046958	nonassociative learning	ARBA:ARBA00084710	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	UNDECIDED
DROME/Pde4	Q9W4S9	7227	GO:0048675	axon extension	ARBA:ARBA00091396	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/Pdk1	Q9W0V1	7227	GO:0048638	regulation of developmental growth	ARBA:ARBA00091468	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|meta	KEEP_AS_NON_CORE
DROME/Pdk1	Q9W0V1	7227	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_a	UNDECIDED
DROME/Pld	A4UZ54	7227	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	phenylacetate_catabolism	KEEP_AS_NON_CORE
DROME/PolG1	Q27607	7227	GO:0006281	DNA repair	ARBA:ARBA00029008	MODULE_INCOMPLETE	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|muth_independent_mismatch_repair	bacterial_nucleotide_excision_repair:liga_sealing|bacterial_recbcd_end_resection:recb_resection|muth_independent_mismatch_repair:repair_synthesis_and_sealing	bacterial_nucleotide_excision_repair:pola_activity|bacterial_recbcd_end_resection:recc_scaffold_activity|muth_independent_mismatch_repair:dna_polymerase_repair_synthesis|muth_independent_mismatch_repair:sbcB_exonuclease	gpi_anchor_remodeling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
DROME/PolG1	Q27607	7227	GO:0071897	DNA biosynthetic process	ARBA:ARBA00028515	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|gpi_anchor_remodeling|muth_independent_mismatch_repair|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
DROME/Prx4	Q9V3Q4	7227	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	MARK_AS_OVER_ANNOTATED
DROME/Prx4	Q9V3Q4	7227	GO:0019725	cellular homeostasis	ARBA:ARBA00027105	MODULE_INCOMPLETE	False	glutathione_thioredoxin_redox_systems	glutathione_thioredoxin_redox_systems:glutathione_glutaredoxin_system	glutathione_thioredoxin_redox_systems:ahp1_activity|glutathione_thioredoxin_redox_systems:bcp_prx_activity|glutathione_thioredoxin_redox_systems:gpx_like_prx_activity|glutathione_thioredoxin_redox_systems:typical_2cys_prx_activity	complex_i_assembly_factors	MODIFY
DROME/Prx4	Q9V3Q4	7227	GO:0042744	hydrogen peroxide catabolic process	ARBA:ARBA00088409	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
DROME/Raf	P11346	7227	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
DROME/Rel	Q94527	7227	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|fgfr_signaling|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondria	MODIFY
DROME/Rel	Q94527	7227	GO:0048468	cell development	ARBA:ARBA00028665	ENTAILED	False	primordial_germ_cell_specification		primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|fgfr_signaling|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondria	MARK_AS_OVER_ANNOTATED
DROME/Rel	Q94527	7227	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|fgfr_signaling|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|neurexin_transsynaptic_a	MARK_AS_OVER_ANNOTATED
DROME/Rel	Q94527	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|fgfr_signaling|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|neurexin_transsynaptic_a	MARK_AS_OVER_ANNOTATED
DROME/RfC38	Q9U9Q1	7227	GO:0006271	DNA strand elongation involved in DNA replication	ARBA:ARBA00028969	NO_MODULE	False				bacterial_recbcd_end_resection	ACCEPT
DROME/RfC38	Q9U9Q1	7227	GO:0006281	DNA repair	ARBA:ARBA00029008	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recc_scaffold_activity		KEEP_AS_NON_CORE
DROME/RluA-1	Q9VKV0	7227	GO:0006396	RNA processing	ARBA:ARBA00028223	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism	MODIFY
DROME/Ser	P18168	7227	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|notch_signaling		egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|notch_signaling:delta_ligand|notch_signaling:dll3_cis_inhibitor|notch_signaling:dos_coligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand	gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion	MODIFY
DROME/Ser	P18168	7227	GO:0007435	salivary gland morphogenesis	ARBA:ARBA00084159	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0008587	imaginal disc-derived wing margin morphogenesis	ARBA:ARBA00085082	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0016330	second mitotic wave involved in compound eye morphogenesis	ARBA:ARBA00086657	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0030718	germ-line stem cell population maintenance	ARBA:ARBA00088373	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0035214	eye-antennal disc development	ARBA:ARBA00091693	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0036011	imaginal disc-derived leg segmentation	ARBA:ARBA00090233	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0042063	gliogenesis	ARBA:ARBA00086246	NOT_ENTAILED	False	nucleokinesis			egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0046331	lateral inhibition	ARBA:ARBA00093161	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	ACCEPT
DROME/Ser	P18168	7227	GO:0048100	wing disc anterior/posterior pattern formation	ARBA:ARBA00089998	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Ser	P18168	7227	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	KEEP_AS_NON_CORE
DROME/Smurf	Q9V853	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|primordial_germ_cell_specification			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/Smurf	Q9V853	7227	GO:0045879	negative regulation of smoothened signaling pathway	ARBA:ARBA00086554	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
DROME/Smurf	Q9V853	7227	GO:0048260	positive regulation of receptor-mediated endocytosis	ARBA:ARBA00089728	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
DROME/Smurf	Q9V853	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/Stim	P83094	7227	GO:0002115	store-operated calcium entry	ARBA:ARBA00087659	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|synaptic_vesicle_cycle|synaptic_vesicle_exocytosis	ACCEPT
DROME/Su-var-2-10	Q7KNF5	7227	GO:0097240	chromosome attachment to the nuclear envelope	ARBA:ARBA00089802	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
DROME/Tace	Q9VAC5	7227	GO:0006509	membrane protein ectodomain proteolysis	ARBA:ARBA00085430	NO_MODULE	False				hedgehog_signaling|mitochondrial_upr|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/Tbh	Q86B61	7227	GO:0006589	octopamine biosynthetic process	ARBA:ARBA00096909	NO_MODULE	False				catecholamine_biosynthesis|complex_i_assembly_factors	ACCEPT
DROME/Toll-7	Q7KIN0	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			notch_signaling|phagocytic_engulfment	KEEP_AS_NON_CORE
DROME/Toll-7	Q7KIN0	7227	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				notch_signaling|phagocytic_engulfment	ACCEPT
DROME/Tps1	Q9Y119	7227	GO:0005991	trehalose metabolic process	ARBA:ARBA00027075	NOT_ENTAILED	False	trey_trez_trehalose_biosynthesis			gpi_anchor_remodeling|osmoregulated_periplasmic_glucan_biosynthesis|peptidoglycan_recycling|phenylacetate_catabolism	MODIFY
DROME/TyrRS	Q9VV60	7227	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|er_unfolded_protein_response|heat_shock_response				MODIFY
DROME/amon	Q9VBC7	7227	GO:0016486	peptide hormone processing	ARBA:ARBA00043631	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
DROME/amon	Q9VBC7	7227	GO:0030537	larval behavior	ARBA:ARBA00086961	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/aub	O76922	7227	GO:0007279	pole cell formation	ARBA:ARBA00085029	NO_MODULE	False				early_metazoan_development|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/aub	O76922	7227	GO:0009994	oocyte differentiation	ARBA:ARBA00084567	NO_MODULE	False				early_metazoan_development|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	KEEP_AS_NON_CORE
DROME/aub	O76922	7227	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				early_metazoan_development|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	MARK_AS_OVER_ANNOTATED
DROME/aub	O76922	7227	GO:0140965	secondary piRNA processing	ARBA:ARBA00087010	NO_MODULE	False				early_metazoan_development|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/aub	O76922	7227	GO:0141009	transposable element silencing by piRNA-mediated mRNA destabilization	ARBA:ARBA00092222	NO_MODULE	False				early_metazoan_development|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/aurB	Q9VKN7	7227	GO:0000280	nuclear division	ARBA:ARBA00028466	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|mitophag	MODIFY
DROME/aurB	Q9VKN7	7227	GO:0000819	sister chromatid segregation	ARBA:ARBA00026649	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	MODIFY
DROME/betaTub97EF	Q8MST5	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			chylomicron_assembly_secretion|complex_i_accessory_subunits|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitochondrial_dynamics|phagocytic_engulfment|phagosome_matur	KEEP_AS_NON_CORE
DROME/betaTub97EF	Q8MST5	7227	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			chylomicron_assembly_secretion|complex_i_accessory_subunits|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitochondrial_dynamics|phagocytic_engulfment|phagosome_matur	KEEP_AS_NON_CORE
DROME/betaTub97EF	Q8MST5	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			chylomicron_assembly_secretion|complex_i_accessory_subunits|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitochondrial_dynamics|phagocytic_engulfment|phagosome_matur	KEEP_AS_NON_CORE
DROME/boi	A8JUV7	7227	GO:0007155	cell adhesion	ARBA:ARBA00028946	NOT_ENTAILED	False	neurexin_transsynaptic_adhesion			fgfr_signaling	MODIFY
DROME/boi	A8JUV7	7227	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			fgfr_signaling	MODIFY
DROME/boi	A8JUV7	7227	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			fgfr_signaling	MODIFY
DROME/cdm	Q9VEC5	7227	GO:0006606	protein import into nucleus	ARBA:ARBA00028627	NO_MODULE	False				cobalamin_intracellular_processing|synaptic_vesicle_exocytosis	ACCEPT
DROME/ci	P19538	7227	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|metazoan_autophagosome_biog	ACCEPT
DROME/dl	P15330	7227	GO:0002225	positive regulation of antimicrobial peptide production	ARBA:ARBA00087827	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/dl	P15330	7227	GO:0007249	canonical NF-kappaB signal transduction	ARBA:ARBA00085080	NOT_ENTAILED	True	nfkb_canonical_signaling			bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/dl	P15330	7227	GO:0008063	Toll signaling pathway	ARBA:ARBA00093120	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/dl	P15330	7227	GO:0035206	regulation of hemocyte proliferation	ARBA:ARBA00091713	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/dl	P15330	7227	GO:0045087	innate immune response	ARBA:ARBA00027946	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/dl	P15330	7227	GO:0048935	peripheral nervous system neuron development	ARBA:ARBA00092968	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	KEEP_AS_NON_CORE
DROME/drk	Q08012	7227	GO:0007173	epidermal growth factor receptor signaling pathway	ARBA:ARBA00034174	ENTAILED	True	egfr_signaling		egfr_signaling:grb2_drk_sem5_adaptor|egfr_signaling:grb2_drk_sem5_sos_adaptor	cgas_sting_signaling|ciliary_transition_zone|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|py	ACCEPT
DROME/drk	Q08012	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor	MARK_AS_OVER_ANNOTATED
DROME/drk	Q08012	7227	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor	MARK_AS_OVER_ANNOTATED
DROME/drk	Q08012	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|p	MARK_AS_OVER_ANNOTATED
DROME/enok	Q9W1A9	7227	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|retinal_determination_network	MODIFY
DROME/ey	O18381	7227	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/ey	O18381	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|retinal_determination_network|wnt_signaling	ACCEPT
DROME/ey	O18381	7227	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/ey	O18381	7227	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specification|wnt_signaling	ACCEPT
DROME/ey	O18381	7227	GO:0090596	sensory organ morphogenesis	ARBA:ARBA00043576	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/ftz-f1	M9NFK2	7227	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	cgas_sting_signaling|er_unfolded_protein_response		cgas_sting_signaling:relish_transcription_factor|er_unfolded_protein_response:hac1_transcription_factor	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|early_metazoan_development|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specification|retinal_determination_network|wnt_s	MODIFY
DROME/hbs	A1Z9X4	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification				MODIFY
DROME/hbs	A1Z9X4	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|primordial_germ_cell_specification				MODIFY
DROME/hbs	A1Z9X4	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network				MODIFY
DROME/hh	Q02936	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	primordial_germ_cell_specification		primordial_germ_cell_specification:pgc_inductive_signal	body_axis_specification|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/hh	Q02936	7227	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			body_axis_specification|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_specification|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/hh	Q02936	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			body_axis_specification|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_specification|protease_activation_cascade	KEEP_AS_NON_CORE
DROME/ihog	Q9VM64	7227	GO:0007155	cell adhesion	ARBA:ARBA00028946	NOT_ENTAILED	False	neurexin_transsynaptic_adhesion			erbb2_signaling|fgfr_signaling|heat_shock_response	MODIFY
DROME/ihog	Q9VM64	7227	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			erbb2_signaling|fgfr_signaling|heat_shock_response	MODIFY
DROME/ihog	Q9VM64	7227	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			erbb2_signaling|fgfr_signaling|heat_shock_response	MODIFY
DROME/klg	Q9VCT4	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			notch_signaling	ACCEPT
DROME/klg	Q9VCT4	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|primordial_germ_cell_specification			notch_signaling	ACCEPT
DROME/klg	Q9VCT4	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			notch_signaling	ACCEPT
DROME/kni	P10734	7227	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|hedgehog_signaling|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specificat	KEEP_AS_NON_CORE
DROME/kni	P10734	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|hedgehog_signaling|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specificat	KEEP_AS_NON_CORE
DROME/loqs	X2J5X6	7227	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			cgas_sting_signaling	ACCEPT
DROME/loqs	X2J5X6	7227	GO:0048477	oogenesis	ARBA:ARBA00028681	NO_MODULE	False				cgas_sting_signaling	KEEP_AS_NON_CORE
DROME/mTor	Q9VK45	7227	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	KEEP_AS_NON_CORE
DROME/mTor	Q9VK45	7227	GO:0008361	regulation of cell size	ARBA:ARBA00091970	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MODIFY
DROME/mTor	Q9VK45	7227	GO:0010507	negative regulation of autophagy	ARBA:ARBA00043537	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MODIFY
DROME/mTor	Q9VK45	7227	GO:0031929	TOR signaling	ARBA:ARBA00086602	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	ACCEPT
DROME/mTor	Q9VK45	7227	GO:0045787	positive regulation of cell cycle	ARBA:ARBA00026693	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mTor	Q9VK45	7227	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mTor	Q9VK45	7227	GO:0045930	negative regulation of mitotic cell cycle	ARBA:ARBA00044434	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	KEEP_AS_NON_CORE
DROME/mTor	Q9VK45	7227	GO:0051094	positive regulation of developmental process	ARBA:ARBA00027577	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mTor	Q9VK45	7227	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mTor	Q9VK45	7227	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mTor	Q9VK45	7227	GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089772	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MODIFY
DROME/mTor	Q9VK45	7227	GO:2000243	positive regulation of reproductive process	ARBA:ARBA00028527	NO_MODULE	False				bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_pho	MARK_AS_OVER_ANNOTATED
DROME/mle	P24785	7227	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|cgas_sting_signaling|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|pirna_mediated_germline_sil	MODIFY
DROME/mof	O02193	7227	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			alginate_o_acetylation|bacterial_l_carnitine_catabolism	MODIFY
DROME/mof	O02193	7227	GO:0140861	DNA repair-dependent chromatin remodeling	ARBA:ARBA00087263	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
DROME/msl-3	P50536	7227	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			ciliary_transition_zone|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesi	MODIFY
DROME/mtDNA-helicase	Q9VL76	7227	GO:0006264	mitochondrial DNA replication	ARBA:ARBA00086414	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
DROME/na	A8JUW5	7227	GO:0035725	sodium ion transmembrane transport	ARBA:ARBA00028214	NO_MODULE	False					ACCEPT
DROME/na	A8JUW5	7227	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False					MODIFY
DROME/olf413	Q6NP60	7227	GO:0006589	octopamine biosynthetic process	ARBA:ARBA00096909	NO_MODULE	False				catecholamine_biosynthesis|complex_i_assembly_factors	KEEP_AS_NON_CORE
DROME/piwi	Q9VKM1	7227	GO:0007279	pole cell formation	ARBA:ARBA00085029	NO_MODULE	False				bacterial_recbcd_end_resection|er_unfolded_protein_response|pirna_mediated_germline_silencing|primordial_germ_cell_specification	KEEP_AS_NON_CORE
DROME/piwi	Q9VKM1	7227	GO:0009994	oocyte differentiation	ARBA:ARBA00084567	NO_MODULE	False				bacterial_recbcd_end_resection|er_unfolded_protein_response|pirna_mediated_germline_silencing|primordial_germ_cell_specification	KEEP_AS_NON_CORE
DROME/piwi	Q9VKM1	7227	GO:0010526	transposable element silencing	ARBA:ARBA00092295	ENTAILED	True	pirna_mediated_germline_silencing		pirna_mediated_germline_silencing:ago3_slicer|pirna_mediated_germline_silencing:aub_slicer|pirna_mediated_germline_silencing:fly_piwi_nuclear|pirna_mediated_germline_silencing:piwi_pirna_guide|pirna_mediated_germline_silencing:piwil2_slicer|pirna_mediated_germline_silencing:piwil4_nuclear	bacterial_recbcd_end_resection|er_unfolded_protein_response|primordial_germ_cell_specification	ACCEPT
DROME/piwi	Q9VKM1	7227	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				bacterial_recbcd_end_resection|er_unfolded_protein_response|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/piwi	Q9VKM1	7227	GO:0034587	piRNA processing	ARBA:ARBA00047257	NO_MODULE	False				bacterial_recbcd_end_resection|er_unfolded_protein_response|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
DROME/piwi	Q9VKM1	7227	GO:0140991	piRNA-mediated gene silencing by mRNA destabilization	ARBA:ARBA00087016	NO_MODULE	False				bacterial_recbcd_end_resection|er_unfolded_protein_response|pirna_mediated_germline_silencing|primordial_germ_cell_specification	KEEP_AS_NON_CORE
DROME/pll	Q05652	7227	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	MARK_AS_OVER_ANNOTATED
DROME/pll	Q05652	7227	GO:0031349	positive regulation of defense response	ARBA:ARBA00028260	ENTAILED	False	cgas_sting_signaling|nlr_signaling|toll_like_receptor_signaling		cgas_sting_signaling:tbk1_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase	coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	ACCEPT
DROME/pll	Q05652	7227	GO:0045087	innate immune response	ARBA:ARBA00027946	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
DROME/pll	Q05652	7227	GO:1902533	positive regulation of intracellular signal transduction	ARBA:ARBA00027124	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
DROME/rad50	Q9W252	7227	GO:0000722	telomere maintenance via recombination	ARBA:ARBA00027344	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MODIFY
DROME/sgg	P18431	7227	GO:0007276	gamete generation	ARBA:ARBA00028211	NOT_ENTAILED	False	primordial_germ_cell_specification			cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
DROME/sgl	O02373	7227	GO:0006024	glycosaminoglycan biosynthetic process	ARBA:ARBA00027325	NOT_ENTAILED	False	d_amino_acid_cell_wall_precursor_supply|gram_negative_lipoprotein_peptidoglycan_tether_remodeling|peptidoglycan_precursor_biosynthesis			complex_i_assembly_factors	KEEP_AS_NON_CORE
DROME/sima	Q24167	7227	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/sns	Q0E9F2	7227	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification				KEEP_AS_NON_CORE
DROME/sns	Q0E9F2	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|primordial_germ_cell_specification				KEEP_AS_NON_CORE
DROME/sns	Q0E9F2	7227	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network				KEEP_AS_NON_CORE
DROME/so	Q27350	7227	GO:0001654	eye development	ARBA:ARBA00027551	ENTAILED	True	retinal_determination_network		retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/so	Q27350	7227	GO:0009887	animal organ morphogenesis	ARBA:ARBA00028067	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	KEEP_AS_NON_CORE
DROME/so	Q27350	7227	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specification|retinal_de	KEEP_AS_NON_CORE
DROME/tgo	O15945	7227	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|mitochondrial_upr|notch_sig	ACCEPT
DROME/tin	P22711	7227	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/tin	P22711	7227	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	nucleokinesis			bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	REMOVE
DROME/tin	P22711	7227	GO:0035050	embryonic heart tube development	ARBA:ARBA00089442	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/tin	P22711	7227	GO:0048565	digestive tract development	ARBA:ARBA00091747	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	MODIFY
DROME/tin	P22711	7227	GO:0055007	cardiac muscle cell differentiation	ARBA:ARBA00084649	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/toy	Q9V490	7227	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	MARK_AS_OVER_ANNOTATED
DROME/toy	Q9V490	7227	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|primordial_germ_cell_specification:pgc_tripartite_network	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|retinal_determination_network|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/toy	Q9V490	7227	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	ACCEPT
DROME/toy	Q9V490	7227	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell_specification|wnt_signaling	MARK_AS_OVER_ANNOTATED
DROME/toy	Q9V490	7227	GO:0090596	sensory organ morphogenesis	ARBA:ARBA00043576	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|notch_signaling|nrf_oxidative_stress_response|primordial_germ_cell	KEEP_AS_NON_CORE
DROME/ttv	D5SHU8	7227	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis				UNDECIDED
DROME/wry	Q7KU08	7227	GO:0000902	cell morphogenesis	ARBA:ARBA00028811	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	MARK_AS_OVER_ANNOTATED
DROME/wry	Q7KU08	7227	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	egfr_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling		egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|gpcr_plc_calcium_pkc_signaling:calmodulin_sensor|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|notch_signaling:delta_ligand|notch_signaling:dll3_cis_inhibitor|notch_signaling:dos_coligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand		MODIFY
DROME/wry	Q7KU08	7227	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	egfr_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling		egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|gpcr_plc_calcium_pkc_signaling:calmodulin_sensor|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|notch_signaling:delta_ligand|notch_signaling:dll3_cis_inhibitor|notch_signaling:dos_coligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand		MODIFY
DROME/wry	Q7KU08	7227	GO:0042063	gliogenesis	ARBA:ARBA00086246	NOT_ENTAILED	False	nucleokinesis			egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	MARK_AS_OVER_ANNOTATED
DROME/wry	Q7KU08	7227	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|notch_signaling	MARK_AS_OVER_ANNOTATED
ECOLI/SecA	P10408	83333	GO:0043952	protein transport by the Sec complex	ARBA:ARBA00086631	MODULE_INCOMPLETE	True	bacterial_sec_posttranslational_protein_export	bacterial_sec_posttranslational_protein_export:secb_precursor_carriage	bacterial_sec_posttranslational_protein_export:seca_export_atpase_activity|bacterial_sec_posttranslational_protein_export:sece_clamp_activity|bacterial_sec_posttranslational_protein_export:secg_channel_accessory_activity|bacterial_sec_posttranslational_protein_export:secy_channel_activity	bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_type_i_secretion|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_v_secretion|bact	ACCEPT
ECOLI/SlyD	P0A9K9	83333	GO:0042026	protein refolding	ARBA:ARBA00043587	NOT_ENTAILED	True	bacterial_dnak_dnaj_refolding_cycle|bacterial_groel_groes_chaperonin_folding			methylcitrate_cycle|phenylacetate_catabolism|retinoid_visual_cycle|urease_biogenesis_urea_hydrolysis	ACCEPT
ECOLI/degP	P0C0V0	83333	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			gram_negative_omp_biogenesis|phenylacetate_catabolism|pqq_biosynthesis|protease_activation_cascade	ACCEPT
ECOLI/lpd	P0A9P0	83333	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	NO_MODULE	False				bacterial_pyruvate_metabolism|branched_chain_amino_acid_catabolism|complex_i_assembly_factors|glycine_cleavage_system|lysine_catabolism|oligosaccharyltransferase_complex|pyruvate_metabolism|tca_cycle	MARK_AS_OVER_ANNOTATED
ECOLI/rlmC	P75817	83333	GO:0009451	RNA modification	ARBA:ARBA00028213	NOT_ENTAILED	False	bacterial_mnma_trna_thiolation|bacterial_preq1_incorporation_queuosine_maturation			bacterial_23s_rrna_m5u747_methylation|bacterial_methionine_cycle|methionine_cycle	KEEP_AS_NON_CORE
ECOLI/yegV	P76419	83333	GO:0006796	phosphate-containing compound metabolic process	ARBA:ARBA00028024	ENTAILED	False	bacterial_nitrogen_regulatory_pts		bacterial_nitrogen_regulatory_pts:npr_phosphocarrier	coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	ACCEPT
EMENI/flbD	G5EAY5	227321	GO:0003006	developmental process involved in reproduction	ARBA:ARBA00026397	ENTAILED	False	conidiation_regulatory_cascade		conidiation_regulatory_cascade:abaA|conidiation_regulatory_cascade:brlA|conidiation_regulatory_cascade:flbB|conidiation_regulatory_cascade:flbC|conidiation_regulatory_cascade:flbD|conidiation_regulatory_cascade:neu_fl|conidiation_regulatory_cascade:neu_wc1|conidiation_regulatory_cascade:neu_wc2|conidiation_regulatory_cascade:sfgA|conidiation_regulatory_cascade:velB|conidiation_regulatory_cascade:vosA	bacterial_recbcd_end_resection|g1_s_transition	KEEP_AS_NON_CORE
EMENI/flbD	G5EAY5	227321	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	conidiation_regulatory_cascade		conidiation_regulatory_cascade:abaA|conidiation_regulatory_cascade:brlA|conidiation_regulatory_cascade:flbB|conidiation_regulatory_cascade:flbC|conidiation_regulatory_cascade:flbD|conidiation_regulatory_cascade:neu_fl|conidiation_regulatory_cascade:neu_wc1|conidiation_regulatory_cascade:neu_wc2|conidiation_regulatory_cascade:sfgA|conidiation_regulatory_cascade:velB|conidiation_regulatory_cascade:vosA	bacterial_recbcd_end_resection|g1_s_transition	KEEP_AS_NON_CORE
EMENI/flbD	G5EAY5	227321	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:0032875	regulation of DNA endoreduplication	ARBA:ARBA00085610	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:0033993	response to lipid	ARBA:ARBA00028073	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:0048582	positive regulation of post-embryonic development	ARBA:ARBA00091211	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:0048731	system development	ARBA:ARBA00027702	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:0048869	cellular developmental process	ARBA:ARBA00026963	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	KEEP_AS_NON_CORE
EMENI/flbD	G5EAY5	227321	GO:0050891	multicellular organismal-level water homeostasis	ARBA:ARBA00091200	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	REMOVE
EMENI/flbD	G5EAY5	227321	GO:0097305	response to alcohol	ARBA:ARBA00033534	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:1901002	positive regulation of response to salt stress	ARBA:ARBA00089230	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	REMOVE
EMENI/flbD	G5EAY5	227321	GO:1902584	positive regulation of response to water deprivation	ARBA:ARBA00092220	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	REMOVE
EMENI/flbD	G5EAY5	227321	GO:1902806	regulation of cell cycle G1/S phase transition	ARBA:ARBA00033981	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	MARK_AS_OVER_ANNOTATED
EMENI/flbD	G5EAY5	227321	GO:2000037	regulation of stomatal complex patterning	ARBA:ARBA00087651	NO_MODULE	False				bacterial_recbcd_end_resection|conidiation_regulatory_cascade|g1_s_transition	REMOVE
EMENI/nudA	P45444	227321	GO:0003006	developmental process involved in reproduction	ARBA:ARBA00026397	NOT_ENTAILED	False	conidiation_regulatory_cascade			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
EMENI/nudA	P45444	227321	GO:0007097	nuclear migration	ARBA:ARBA00026920	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
EMENI/nudA	P45444	227321	GO:0048468	cell development	ARBA:ARBA00028665	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
EMENI/nudA	P45444	227321	GO:0048731	system development	ARBA:ARBA00027702	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	REMOVE
EMENI/nudA	P45444	227321	GO:0072384	organelle transport along microtubule	ARBA:ARBA00045035	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
EMENI/wA	Q03149	227321	GO:0046148	pigment biosynthetic process	ARBA:ARBA00027688	NOT_ENTAILED	False	carotene_backbone_biosynthesis|heme_biosynthesis|siroheme_biosynthesis			alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_unsaturated_fatty_acid_biosynthesis|complex_i_assembly_factors|conidiation_regulatory_cascade|type_ii_fatty_acid_synthesis	ACCEPT
EMENI/yA	P17489	227321	GO:0042440	pigment metabolic process	ARBA:ARBA00028008	NOT_ENTAILED	False	carotene_backbone_biosynthesis|heme_biosynthesis|heme_degradation|siroheme_biosynthesis			complex_i_assembly_factors|conidiation_regulatory_cascade	ACCEPT
ENTCL/aac6-Ib	A0A076UB44	550	GO:0046677	response to antibiotic	ARBA:ARBA00026946	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization	ACCEPT
GADMO/A0A8C5FPT8	A0A8C5FPT8	8049	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	MODULE_INCOMPLETE	False	synaptic_vesicle_exocytosis	synaptic_vesicle_exocytosis:vesicle_priming|synaptic_vesicle_exocytosis:presynaptic_calcium_influx	synaptic_vesicle_exocytosis:rim_active_zone_effector	dolichol_phosphate_sugar_donor_supply|gtpase_switch|sphingolipid_de_novo_synthesis	ACCEPT
HETGA/Cd44	A0AAX6R0R7	10181	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			cobalamin_absorption_transport|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
HETGA/Cd44	A0AAX6R0R7	10181	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			cobalamin_absorption_transport|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
HETGA/Cd44	A0AAX6R0R7	10181	GO:2000106	regulation of leukocyte apoptotic process	ARBA:ARBA00088582	NO_MODULE	False				cobalamin_absorption_transport|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
HETGA/Ntrk1	A0AAX6QC09	10181	GO:0031175	neuron projection development	ARBA:ARBA00026765	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
HETGA/Ntrk1	A0AAX6QC09	10181	GO:0043524	negative regulation of neuron apoptotic process	ARBA:ARBA00085502	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
HORSE/ALDH7A1	A0A9L0RRL6	9796	GO:0019477	L-lysine catabolic process	ARBA:ARBA00084340	ENTAILED	True	lysine_catabolism_saccharopine		lysine_catabolism_saccharopine:aldh7a1_activity	complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|phenylacetate_catabolism	UNDECIDED
HORSE/BCAT2	A0A9L0TSN4	9796	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	ENTAILED	True	branched_chain_amino_acid_catabolism		branched_chain_amino_acid_catabolism:bcat2_activity	branched_chain_amino_acid_biosynthesis|ubiquinone_biosynthesis	ACCEPT
HORSE/GHSR	F6QF00	9796	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	fgfr_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling		fgfr_signaling:klotho_coreceptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|hedgehog_signaling:gpr161_camp_brake|hedgehog_signaling:smo_transducer|notch_signaling:notch_receptor	cerebellum_development	KEEP_AS_NON_CORE
HORSE/GHSR	F6QF00	9796	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	fgfr_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling		fgfr_signaling:klotho_coreceptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|hedgehog_signaling:gpr161_camp_brake|hedgehog_signaling:smo_transducer|notch_signaling:notch_receptor	cerebellum_development	KEEP_AS_NON_CORE
HORSE/KRIT1	A0A9L0SR44	9796	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False					KEEP_AS_NON_CORE
HORSE/KRIT1	A0A9L0SR44	9796	GO:2000026	regulation of multicellular organismal development	ARBA:ARBA00026275	NO_MODULE	False					KEEP_AS_NON_CORE
HORSE/MAP2K2	A0A9L0SHX8	9796	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	UNDECIDED
HORSE/MAP2K2	A0A9L0SHX8	9796	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	UNDECIDED
HORSE/MAP2K2	A0A9L0SHX8	9796	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	UNDECIDED
HORSE/PEA15	A0A9L0RWM8	9796	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	ARBA:ARBA00088654	NO_MODULE	False					ACCEPT
HORVU/MLA10	Q6WWJ4	4513	GO:0002758	innate immune response-activating signaling pathway	ARBA:ARBA00034398	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling				ACCEPT
HORVU/MLA10	Q6WWJ4	4513	GO:0009626	plant-type hypersensitive response	ARBA:ARBA00091908	NOT_ENTAILED	True	plant_nlr_resistosome_signaling				KEEP_AS_NON_CORE
HORVU/MLA10	Q6WWJ4	4513	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False					REMOVE
MEDTR/NFP	Q0GXS4	3880	GO:0051707	response to other organism	ARBA:ARBA00029118	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling			coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
MEDTR/NSP1	Q4VYC8	3880	GO:0009610	response to symbiotic fungus	ARBA:ARBA00026468	NO_MODULE	False					KEEP_AS_NON_CORE
MEDTR/PT4	Q8GSG4	3880	GO:0009610	response to symbiotic fungus	ARBA:ARBA00026468	NO_MODULE	False					KEEP_AS_NON_CORE
MEDTR/PT4	Q8GSG4	3880	GO:0036377	arbuscular mycorrhizal association	ARBA:ARBA00089448	NO_MODULE	False					ACCEPT
MEDTR/PT4	Q8GSG4	3880	GO:0043562	cellular response to nitrogen levels	ARBA:ARBA00034586	NO_MODULE	False					REMOVE
METEA/serA	C5APD6	272630	GO:0006564	L-serine biosynthetic process	ARBA:ARBA00093701	ENTAILED	True	phosphorylated_serine_biosynthesis|serine_biosynthesis_one_carbon		phosphorylated_serine_biosynthesis:serA_activity|serine_biosynthesis_one_carbon:phgdh_activity	bacterial_beta_aryl_ether_dimer_cleavage|bacterial_sulfoquinovose_catabolism|complex_i_assembly_factors	ACCEPT
MISSI/CAD	A0A0M3TCH3	62337	GO:0009809	lignin biosynthetic process	ARBA:ARBA00034952	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
MISSI/CDT1	B5BSU2	62337	GO:0010038	response to metal ion	ARBA:ARBA00028342	NO_MODULE	False					KEEP_AS_NON_CORE
MISSI/MnSOD	A0A088MDT8	62337	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	KEEP_AS_NON_CORE
MISSI/ramosa1	Q3ZDP4	62337	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False					ACCEPT
MYCTU/cds1	O69652	83332	GO:1901605	alpha-amino acid metabolic process	ARBA:ARBA00026968	NO_MODULE	False					ACCEPT
NEMVE/G9JWI5	G9JWI5	45351	GO:0003008	system process	ARBA:ARBA00026405	NOT_ENTAILED	False	retinoid_visual_cycle			gpcr_plc_calcium_pkc_signaling	REMOVE
NEMVE/G9JWI5	G9JWI5	45351	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	NOT_ENTAILED	False	erbb2_signaling|fgfr_signaling|hedgehog_signaling|insulin_receptor_signaling|integrin_fak_src_signaling			gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
NEMVE/G9JWI5	G9JWI5	45351	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	nucleokinesis			gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
NEMVE/G9JWI5	G9JWI5	45351	GO:0009952	anterior/posterior pattern specification	ARBA:ARBA00027259	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
NEMVE/G9JWI5	G9JWI5	45351	GO:0030097	hemopoiesis	ARBA:ARBA00028409	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	REMOVE
NEMVE/G9JWI5	G9JWI5	45351	GO:0035282	segmentation	ARBA:ARBA00091150	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	REMOVE
NEMVE/G9JWI5	G9JWI5	45351	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	NOT_ENTAILED	False	germ_layer_specification			gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
NEMVE/G9JWI5	G9JWI5	45351	GO:0048863	stem cell differentiation	ARBA:ARBA00090702	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
NEMVE/G9JWI5	G9JWI5	45351	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
NEMVE/G9JWI6	G9JWI6	45351	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	nucleokinesis			gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
NEMVE/G9JWI6	G9JWI6	45351	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	nucleokinesis|primordial_germ_cell_specification			gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
NEUCR/NCU08595	Q7SCN3	367110	GO:0042254	ribosome biogenesis	ARBA:ARBA00026817	NO_MODULE	False					MODIFY
NEUCR/al-1	P21334	367110	GO:0008299	isoprenoid biosynthetic process	ARBA:ARBA00027662	ENTAILED	False	carotene_backbone_biosynthesis		carotene_backbone_biosynthesis:crti_activity|carotene_backbone_biosynthesis:pds_activity	complex_i_assembly_factors	KEEP_AS_NON_CORE
NEUCR/hsp98	P31540	367110	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
NEUCR/hsp98	P31540	367110	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
NEUCR/hsp98	P31540	367110	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
NEUCR/mek-1	Q7RYZ6	367110	GO:0000165	MAPK cascade	ARBA:ARBA00029221	ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade		erk5_cascade:erk5_map2k_activity|erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|jnk_cascade:jnk_map2k_activity|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:map2k_activity|mapk_relay:mapk_activity|p38_cascade:p38_map2k_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
NICAT/NaBGL1_candidate_BGLU42	A0A314LBF6	49451	GO:0009821	alkaloid biosynthetic process	ARBA:ARBA00028022	NO_MODULE	False				phenylacetate_catabolism	REMOVE
NICAT/NaPMT1.1	Q93XQ5	49451	GO:0009753	response to jasmonic acid	ARBA:ARBA00028898	NOT_ENTAILED	False	jasmonate_coi1_jaz_signaling			bacterial_methionine_cycle|methionine_biosynthesis|methionine_cycle|polyamine_metabolism	KEEP_AS_NON_CORE
NICAT/NaPMT1.2	Q93XQ4	49451	GO:0009753	response to jasmonic acid	ARBA:ARBA00028898	NOT_ENTAILED	False	jasmonate_coi1_jaz_signaling			bacterial_methionine_cycle|methionine_biosynthesis|methionine_cycle|polyamine_metabolism	KEEP_AS_NON_CORE
NICAT/NaPMT3	A0A314LG79	49451	GO:0009753	response to jasmonic acid	ARBA:ARBA00028898	NOT_ENTAILED	False	jasmonate_coi1_jaz_signaling			bacterial_methionine_cycle|methionine_biosynthesis|methionine_cycle|polyamine_metabolism	KEEP_AS_NON_CORE
NICAT/NaQPT2_candidate_QPT_0	A0A1J6KEF3	49451	GO:0009611	response to wounding	ARBA:ARBA00026469	NO_MODULE	False				kynurenine_nad_de_novo|nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal	KEEP_AS_NON_CORE
NICAT/NaQPT2_candidate_QPT_1	A0A1J6IKI8	49451	GO:0009611	response to wounding	ARBA:ARBA00026469	NO_MODULE	False				kynurenine_nad_de_novo|nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal	KEEP_AS_NON_CORE
ORYSJ/CPS4	Q0JF02	39947	GO:0006721	terpenoid metabolic process	ARBA:ARBA00027870	ENTAILED	False	rice_momilactone_biosynthesis		rice_momilactone_biosynthesis:cps4_step_activity	methylcitrate_cycle|phenylacetate_catabolism	MODIFY
ORYSJ/EIL2	Q8W3L9	39947	GO:0010104	regulation of ethylene-activated signaling pathway	ARBA:ARBA00027580	NO_MODULE	False				bacterial_recbcd_end_resection|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling	ACCEPT
ORYSJ/EIL2	Q8W3L9	39947	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				bacterial_recbcd_end_resection|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling	ACCEPT
ORYSJ/HD3A	Q93WI9	39947	GO:0009909	regulation of flower development	ARBA:ARBA00043323	NO_MODULE	False					ACCEPT
ORYSJ/HD3A	Q93WI9	39947	GO:0010229	inflorescence development	ARBA:ARBA00090608	NO_MODULE	False					KEEP_AS_NON_CORE
ORYSJ/HD3A	Q93WI9	39947	GO:0048510	regulation of timing of transition from vegetative to reproductive phase	ARBA:ARBA00091784	NO_MODULE	False					ACCEPT
ORYSJ/HD3A	Q93WI9	39947	GO:0048573	photoperiodism, flowering	ARBA:ARBA00091187	NO_MODULE	False					ACCEPT
ORYSJ/MADS3	Q40704	39947	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NO_MODULE	False				bacterial_recbcd_end_resection|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling	MARK_AS_OVER_ANNOTATED
ORYSJ/MADS3	Q40704	39947	GO:0048608	reproductive structure development	ARBA:ARBA00028277	NO_MODULE	False				bacterial_recbcd_end_resection|gibberellin_della_signaling|jasmonate_coi1_jaz_signaling	MODIFY
ORYSJ/MET1A	Q7Y1I7	39947	GO:0045814	negative regulation of gene expression, epigenetic	ARBA:ARBA00033599	NO_MODULE	False				bacterial_methionine_cycle|bacterial_recbcd_end_resection|methionine_cycle	KEEP_AS_NON_CORE
ORYSJ/PIKM1-TS	B5UBC1	39947	GO:0051707	response to other organism	ARBA:ARBA00029118	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling				MODIFY
ORYSJ/Pi-ta	Q84UB1	39947	GO:0002758	innate immune response-activating signaling pathway	ARBA:ARBA00034398	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling				MARK_AS_OVER_ANNOTATED
ORYSJ/Pi-ta	Q84UB1	39947	GO:0009626	plant-type hypersensitive response	ARBA:ARBA00091908	NOT_ENTAILED	True	plant_nlr_resistosome_signaling				MARK_AS_OVER_ANNOTATED
ORYSJ/Pi-ta	Q84UB1	39947	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False					REMOVE
ORYSJ/RGA4	F7J0M4	39947	GO:0002758	innate immune response-activating signaling pathway	ARBA:ARBA00034398	NOT_ENTAILED	False	chitin_perception|plant_nlr_resistosome_signaling				ACCEPT
ORYSJ/RGA4	F7J0M4	39947	GO:0009626	plant-type hypersensitive response	ARBA:ARBA00091908	NOT_ENTAILED	True	plant_nlr_resistosome_signaling				ACCEPT
ORYSJ/RGA4	F7J0M4	39947	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
ORYSJ/RGA5	F7J0N2	39947	GO:0002758	innate immune response-activating signaling pathway	ARBA:ARBA00034398	ENTAILED	False	plant_nlr_resistosome_signaling		plant_nlr_resistosome_signaling:roq1_tnl|plant_nlr_resistosome_signaling:rpp1_tnl|plant_nlr_resistosome_signaling:zar1_sensor		ACCEPT
ORYSJ/RGA5	F7J0N2	39947	GO:0009626	plant-type hypersensitive response	ARBA:ARBA00091908	ENTAILED	True	plant_nlr_resistosome_signaling		plant_nlr_resistosome_signaling:roq1_tnl|plant_nlr_resistosome_signaling:rpp1_tnl|plant_nlr_resistosome_signaling:zar1_sensor		KEEP_AS_NON_CORE
ORYSJ/RGA5	F7J0N2	39947	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False				plant_nlr_resistosome_signaling	MARK_AS_OVER_ANNOTATED
PANAN/crtB	P21683	553	GO:0016117	carotenoid biosynthetic process	ARBA:ARBA00028033	MODULE_INCOMPLETE	True	carotene_backbone_biosynthesis	carotene_backbone_biosynthesis:phytoene_desaturation_to_lycopene	carotene_backbone_biosynthesis:psy_activity	isoprenoid_diphosphate_biosynthesis|methionine_biosynthesis|sterol_commitment_squalene_to_lanosterol	ACCEPT
PANAN/crtI	P21685	553	GO:0016120	carotene biosynthetic process	ARBA:ARBA00028053	NOT_ENTAILED	True	carotene_backbone_biosynthesis			complex_i_assembly_factors	ACCEPT
PANPA/A0A2R9CAF4	A0A2R9CAF4	9597	GO:0015698	inorganic anion transport	ARBA:ARBA00027809	NO_MODULE	False				bcl2_family_momp_control	KEEP_AS_NON_CORE
PENCH/aatA	P15802	5076	GO:0042318	penicillin biosynthetic process	ARBA:ARBA00087383	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
PENEN/patI	A0A075TMP8	27334	GO:0044550	secondary metabolite biosynthetic process	ARBA:ARBA00029064	NO_MODULE	False				complex_i_assembly_factors|mitochondrial_complex_ii	KEEP_AS_NON_CORE
PHYPA/MPK4a	A9T142	3218	GO:0002221	pattern recognition receptor signaling pathway	ARBA:ARBA00033911	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|ethylene_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|sphingolipid_de_	ACCEPT
POPTR/MAOX	P34105	3694	GO:0006108	malate metabolic process	ARBA:ARBA00026488	NO_MODULE	False				complex_i_assembly_factors|type_ii_fatty_acid_synthesis	ACCEPT
POPTR/PAL	P45730	3694	GO:0009611	response to wounding	ARBA:ARBA00026469	NO_MODULE	False					KEEP_AS_NON_CORE
POPTR/PAL	P45730	3694	GO:0046395	carboxylic acid catabolic process	ARBA:ARBA00027882	NOT_ENTAILED	False	arginine_catabolism_arginase_pathway|aspartate_asparagine_metabolism|branched_chain_amino_acid_catabolism|fatty_acid_beta_oxidation|glucarate_galactarate_catabolism				MODIFY
POPTR/PCBER	B9HRL7	3694	GO:0009807	lignan biosynthetic process	ARBA:ARBA00027900	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
POPTR/RBL901	B9GLX8	3694	GO:0032875	regulation of DNA endoreduplication	ARBA:ARBA00085610	NO_MODULE	False				bacterial_recbcd_end_resection	KEEP_AS_NON_CORE
POPTR/WIN6.2B	P29031	3694	GO:0050832	defense response to fungus	ARBA:ARBA00029244	NO_MODULE	False				chitin_perception|phenylacetate_catabolism	ACCEPT
POPTR/WIN6.2C	P29032	3694	GO:0098542	defense response to other organism	ARBA:ARBA00027395	NOT_ENTAILED	False	plant_nlr_resistosome_signaling			chitin_perception|phenylacetate_catabolism	ACCEPT
POPTR/WIN6	P16579	3694	GO:0050832	defense response to fungus	ARBA:ARBA00029244	NO_MODULE	False				chitin_perception|phenylacetate_catabolism	ACCEPT
PSEAE/ubiE	Q9HUC0	208964	GO:0042181	ketone biosynthetic process	ARBA:ARBA00027493	ENTAILED	False	ubiquinone_biosynthesis		ubiquinone_biosynthesis:c_methyltransferase_activity|ubiquinone_biosynthesis:coq5_c_methyltransferase_activity	methionine_cycle	MARK_AS_OVER_ANNOTATED
PSEAI/merA	P00392	287	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	NO_MODULE	False				complex_i_assembly_factors	REMOVE
PSEPK/BenR	Q88I42	160488	GO:0009893	positive regulation of metabolic process	ARBA:ARBA00028097	NO_MODULE	False				bacterial_recbcd_end_resection|pseudomonad_gac_lifestyle_phosphorelay	KEEP_AS_NON_CORE
PSEPK/PP_1451	Q88MW7	160488	GO:0000270	peptidoglycan metabolic process	ARBA:ARBA00028428	NOT_ENTAILED	True	bacterial_divisome_peptidoglycan_transpeptidation|bacterial_rod_complex_peptidoglycan_transpeptidation|d_amino_acid_cell_wall_precursor_supply|gram_negative_lipoprotein_peptidoglycan_tether_remodeling|low_molecular_mass_pbp_peptidoglycan_hydrolysis			phenylacetate_catabolism|pqq_biosynthesis|protease_activation_cascade	ACCEPT
PSEPK/PP_2320	Q88KH0	160488	GO:0000270	peptidoglycan metabolic process	ARBA:ARBA00028428	ENTAILED	False	gram_negative_lipoprotein_peptidoglycan_tether_remodeling		gram_negative_lipoprotein_peptidoglycan_tether_remodeling:erfk_lipoprotein_anchoring	phenylacetate_catabolism|pqq_biosynthesis|protease_activation_cascade	ACCEPT
PSEPK/aceA	Q88FI0	160488	GO:0006097	glyoxylate cycle	ARBA:ARBA00084698	NO_MODULE	False					ACCEPT
PSEPK/algC	Q88C93	160488	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_divisome_peptidoglycan_transpeptidation|bacterial_rod_complex_peptidoglycan_transpeptidation|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis			emp_glycolysis|glycogenolysis|methylcitrate_cycle|phenylacetate_catabolism|udp_glucose_and_udp_galactose_biosynthesis	KEEP_AS_NON_CORE
PSEPK/carB	Q88DU6	160488	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:cpsa_large_subunit_activity	de_novo_pyrimidine_synthesis|urea_cycle	MARK_AS_OVER_ANNOTATED
PSEPK/catB	Q88GK6	160488	GO:0006518	peptide metabolic process	ARBA:ARBA00026402	NOT_ENTAILED	False	glutathione_biosynthesis|pseudomonas_pyoverdine_precursor_supply			catechol_ortho_cleavage|methylcitrate_cycle|phenylacetate_catabolism	REMOVE
PSEPK/cbcV	Q88R40	160488	GO:0006970	response to osmotic stress	ARBA:ARBA00026252	NO_MODULE	False				bacterial_choline_to_glycine_betaine_biosynthesis|bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacteria	MARK_AS_OVER_ANNOTATED
PSEPK/cca	Q88QU2	160488	GO:0042780	tRNA 3'-end processing	ARBA:ARBA00028910	NO_MODULE	False				bacterial_nitrogen_regulatory_pts|gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism|pseudomonad_cbr_crc_catabolite_control|sphingolipid_de_novo_synthesis	ACCEPT
PSEPK/ccmH	A0A140FWM4	160488	GO:0017004	cytochrome complex assembly	ARBA:ARBA00086146	NOT_ENTAILED	False	bacterial_cytochrome_c_maturation_system_i|complex_iv_assembly_factors|mitochondrial_complex_iii|mitochondrial_complex_iv				MODIFY
PSEPK/davT	Q88RB9	160488	GO:0019477	L-lysine catabolic process	ARBA:ARBA00084340	ENTAILED	True	lysine_dav_catabolism		lysine_dav_catabolism:davT_activity	ubiquinone_biosynthesis	ACCEPT
PSEPK/dinB	Q88NK4	160488	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	ENTAILED	False	bacterial_imuabc_damage_induced_mutagenesis|bacterial_nonhomologous_end_joining|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection		bacterial_imuabc_damage_induced_mutagenesis:dnae2_polymerase|bacterial_nonhomologous_end_joining:ligd_polymerase_activity|bacterial_nucleotide_excision_repair:pola_activity|bacterial_nucleotide_excision_repair:uvra_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_nitrogen_regulatory_pts|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
PSEPK/dnaE2	Q88I82	160488	GO:0006974	DNA damage response	ARBA:ARBA00026271	ENTAILED	False	bacterial_imuabc_damage_induced_mutagenesis|bacterial_nonhomologous_end_joining|bacterial_nucleotide_excision_repair		bacterial_imuabc_damage_induced_mutagenesis:dnae2_polymerase|bacterial_nonhomologous_end_joining:ligd_polymerase_activity|bacterial_nucleotide_excision_repair:pola_activity	bacterial_chromosomal_dna_replication|bacterial_nitrogen_regulatory_pts|gpi_anchor_remodeling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
PSEPK/efp	Q88LS0	160488	GO:0006417	regulation of translation	ARBA:ARBA00027123	MODULE_INCOMPLETE	False	selenocysteine_biosynthesis_incorporation	selenocysteine_biosynthesis_incorporation:lineage_specific_sec_route	selenocysteine_biosynthesis_incorporation:eefsec_activity|selenocysteine_biosynthesis_incorporation:selb_activity	efp_translation_stall_rescue	KEEP_AS_NON_CORE
PSEPK/efp	Q88LS0	160488	GO:0072344	rescue of stalled cytosolic ribosome	ARBA:ARBA00043322	ENTAILED	True	efp_translation_stall_rescue		efp_translation_stall_rescue:efp_translation_elongation_factor	selenocysteine_biosynthesis_incorporation	ACCEPT
PSEPK/fabG	Q88LL6	160488	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	NOT_ENTAILED	True	fatty_acid_elongation_cycle			bacterial_beta_aryl_ether_dimer_cleavage|bacterial_sulfoquinovose_catabolism|complex_i_assembly_factors|type_ii_fatty_acid_synthesis	ACCEPT
PSEPK/fruK	Q88PQ4	160488	GO:0016052	carbohydrate catabolic process	ARBA:ARBA00028828	ENTAILED	False	fructose_pts_uptake_and_catabolism		fructose_pts_uptake_and_catabolism:fruk_activity	bacterial_nitrogen_regulatory_pts|coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|tres_mak_glge_branched_alpha_glucan_biosynthesis	MODIFY
PSEPK/galC	Q88JX9	160488	GO:0019336	phenol-containing compound catabolic process	ARBA:ARBA00027340	ENTAILED	False	bacterial_gallate_catabolism		bacterial_gallate_catabolism:galc_cha_aldolase		MARK_AS_OVER_ANNOTATED
PSEPK/galC	Q88JX9	160488	GO:0042537	benzene-containing compound metabolic process	ARBA:ARBA00027366	ENTAILED	False	bacterial_gallate_catabolism		bacterial_gallate_catabolism:galc_cha_aldolase		MARK_AS_OVER_ANNOTATED
PSEPK/galC	Q88JX9	160488	GO:0072329	monocarboxylic acid catabolic process	ARBA:ARBA00027114	ENTAILED	False	bacterial_gallate_catabolism		bacterial_gallate_catabolism:galc_cha_aldolase		MARK_AS_OVER_ANNOTATED
PSEPK/glgB	Q88FN1	160488	GO:0044042	glucan metabolic process	ARBA:ARBA00027007	ENTAILED	False	tres_mak_glge_branched_alpha_glucan_biosynthesis		tres_mak_glge_branched_alpha_glucan_biosynthesis:glgb_activity|tres_mak_glge_branched_alpha_glucan_biosynthesis:glge_activity	phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
PSEPK/glgP	Q88CY8	160488	GO:0005977	glycogen metabolic process	ARBA:ARBA00028497	ENTAILED	False	glycogenolysis		glycogenolysis:phosphorylase_activity	glycogen_synthesis_and_mobilization|tres_mak_glge_branched_alpha_glucan_biosynthesis	KEEP_AS_NON_CORE
PSEPK/gyrA	Q88M08	160488	GO:0051276	chromosome organization	ARBA:ARBA00028775	NO_MODULE	False				bacterial_recbcd_end_resection|methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
PSEPK/gyrB	Q88RW6	160488	GO:0051276	chromosome organization	ARBA:ARBA00028775	NO_MODULE	False				bacterial_recbcd_end_resection|methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
PSEPK/hemB	Q88IT6	160488	GO:0006779	porphyrin-containing compound biosynthetic process	ARBA:ARBA00027896	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:alad_activity	bacterial_sulfoquinovose_catabolism|methylcitrate_cycle	KEEP_AS_NON_CORE
PSEPK/hemBB	Q88HN1	160488	GO:0006779	porphyrin-containing compound biosynthetic process	ARBA:ARBA00027896	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:alad_activity	bacterial_sulfoquinovose_catabolism|methylcitrate_cycle	KEEP_AS_NON_CORE
PSEPK/hemE	Q88CV6	160488	GO:0006778	porphyrin-containing compound metabolic process	ARBA:ARBA00027898	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:urod_activity	bacterial_carboxyspermidine_biosynthesis|bacterial_flavonoid_degradation|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
PSEPK/kdpE	Q88FE0	160488	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				bacterial_chemotaxis_signal_transduction|bacterial_kdp_potassium_homeostasis|bacterial_nonhomologous_end_joining|bacterial_ntr_nitrogen_regulation|bacterial_recbcd_end_resection|crispr_cas_adaptive_immunity|pseudomonad_cbr_crc_catabolite_control|pseudomonad_gac_lifestyle_phosphorelay|pseudomonad_lan	ACCEPT
PSEPK/kdsA1	Q88MG0	160488	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	kdo_biosynthesis|methionine_biosynthesis		kdo_biosynthesis:kdsA1_activity|kdo_biosynthesis:kdsA2_activity|methionine_biosynthesis:metZ_activity		MARK_AS_OVER_ANNOTATED
PSEPK/lcdH	Q88R32	160488	GO:0042413	carnitine catabolic process	ARBA:ARBA00087193	ENTAILED	True	bacterial_l_carnitine_catabolism		bacterial_l_carnitine_catabolism:lcdh_activity	bacterial_beta_aryl_ether_dimer_cleavage|bacterial_sulfoquinovose_catabolism|complex_i_assembly_factors	ACCEPT
PSEPK/leuC	Q88LE8	160488	GO:0043436	oxoacid metabolic process	ARBA:ARBA00027279	ENTAILED	False	branched_chain_amino_acid_biosynthesis|methylcitrate_cycle		branched_chain_amino_acid_biosynthesis:leu1_fused_activity|branched_chain_amino_acid_biosynthesis:leuC_activity|branched_chain_amino_acid_biosynthesis:leuD_activity|methylcitrate_cycle:acnD_pathway_dehydratase	bacterial_sulfoquinovose_catabolism|mitochondrial_complex_i_core	MARK_AS_OVER_ANNOTATED
PSEPK/lpd	Q88C17	160488	GO:0045333	cellular respiration	ARBA:ARBA00026750	ENTAILED	False	tca_cycle		tca_cycle:dihydrolipoyl_dehydrogenase_activity	bacterial_pyruvate_metabolism|branched_chain_amino_acid_catabolism|complex_i_assembly_factors|glycine_cleavage_system|lysine_catabolism|pyruvate_metabolism	MARK_AS_OVER_ANNOTATED
PSEPK/mazG	Q88MB7	160488	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_imuabc_damage_induced_mutagenesis|bacterial_nonhomologous_end_joining|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing			phenylacetate_catabolism	UNDECIDED
PSEPK/mlaF	Q88P94	160488	GO:0006869	lipid transport	ARBA:ARBA00027046	ENTAILED	False	bacterial_lps_transport		bacterial_lps_transport:lptb_atpase	bacterial_cytochrome_c_maturation_system_i|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secretion_apparatus|coenzyme_q10_biosynthesis|muth_independent_m	MODIFY
PSEPK/moaE	Q88NB8	160488	GO:0032324	molybdopterin cofactor biosynthetic process	ARBA:ARBA00043347	MODULE_INCOMPLETE	False	molybdenum_cofactor_biosynthesis	molybdenum_cofactor_biosynthesis:mo_mpt_formation	molybdenum_cofactor_biosynthesis:moaDE_mpt_synthase_complex		MARK_AS_OVER_ANNOTATED
PSEPK/murG	Q88N76	160488	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	ENTAILED	False	peptidoglycan_precursor_biosynthesis		peptidoglycan_precursor_biosynthesis:murG_activity	tres_mak_glge_branched_alpha_glucan_biosynthesis	MARK_AS_OVER_ANNOTATED
PSEPK/mutL	Q88DD1	160488	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	ENTAILED	False	bacterial_imuabc_damage_induced_mutagenesis|bacterial_nonhomologous_end_joining|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection		bacterial_imuabc_damage_induced_mutagenesis:reca_damage_sensor|bacterial_nonhomologous_end_joining:ku_double_stranded_dna_binding|bacterial_nucleotide_excision_repair:uvrb_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_pst_phosphate_uptake|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secretion_apparatus|coenzyme_q10_biosynthesis|crispr_cas_adaptive_immunity|ph	MARK_AS_OVER_ANNOTATED
PSEPK/nadD	Q88DL5	160488	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage		nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity	bacterial_nitrogen_regulatory_pts|sphingolipid_de_novo_synthesis	MODIFY
PSEPK/nicC	Q88FY2	160488	GO:1901848	nicotinate catabolic process	ARBA:ARBA00091462	ENTAILED	True	aerobic_nicotinate_degradation		aerobic_nicotinate_degradation:nicc_activity	bacterial_flavonoid_degradation|complex_i_assembly_factors|pqq_biosynthesis	ACCEPT
PSEPK/nuoC	Q88FH5	160488	GO:0022904	respiratory electron transport chain	ARBA:ARBA00033493	ENTAILED	True	electron_transfer_flavoprotein_system|mitochondrial_complex_i_core|mitochondrial_complex_ii		electron_transfer_flavoprotein_system:etfa_activity|electron_transfer_flavoprotein_system:etfb_activity|mitochondrial_complex_i_core:ndufs1_activity|mitochondrial_complex_i_core:ndufs7_activity|mitochondrial_complex_i_core:ndufv1_activity|mitochondrial_complex_i_core:ndufv2_activity|mitochondrial_complex_ii:sdhb_activity	bacterial_chemotaxis_signal_transduction|bacterial_isc_iron_sulfur_cluster_assembly|bacterial_respiratory_complex_i|complex_i_assembly_factors|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_v|ubiquinone_biosynthesis	ACCEPT
PSEPK/paaH	Q88HS1	160488	GO:0032787	monocarboxylic acid metabolic process	ARBA:ARBA00027288	ENTAILED	False	bacterial_fatty_acid_beta_oxidation|fatty_acid_beta_oxidation|phenylacetate_catabolism		bacterial_fatty_acid_beta_oxidation:fadb_hydroxyacyl_coa_dehydrogenase_activity|fatty_acid_beta_oxidation:sc_hadh_activity|phenylacetate_catabolism:paaH_dehydrogenase	bacterial_beta_aryl_ether_dimer_cleavage|bacterial_sulfoquinovose_catabolism|complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
PSEPK/pcaF	Q88N39	160488	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	bacterial_fatty_acid_beta_oxidation|fatty_acid_beta_oxidation		bacterial_fatty_acid_beta_oxidation:fada_ketoacyl_coa_thiolase_activity|fatty_acid_beta_oxidation:lc_thiolase_activity|fatty_acid_beta_oxidation:med_thiolase_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization|beta_ketoadipate_lower_pathway|phenylacetate_catabolism	REMOVE
PSEPK/pgsA	Q88FJ8	160488	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	bacterial_phosphatidylglycerol_cardiolipin_biosynthesis		bacterial_phosphatidylglycerol_cardiolipin_biosynthesis:pgsA_activity	bacterial_nitrogen_regulatory_pts	MODIFY
PSEPK/pgsA	Q88FJ8	160488	GO:0019637	organophosphate metabolic process	ARBA:ARBA00028049	ENTAILED	False	bacterial_phosphatidylglycerol_cardiolipin_biosynthesis		bacterial_phosphatidylglycerol_cardiolipin_biosynthesis:pgsA_activity	bacterial_nitrogen_regulatory_pts|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
PSEPK/pgsA	Q88FJ8	160488	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NOT_ENTAILED	False	bacterial_rod_complex_peptidoglycan_transpeptidation			bacterial_nitrogen_regulatory_pts|bacterial_phosphatidylglycerol_cardiolipin_biosynthesis|sphingolipid_de_novo_synthesis	REMOVE
PSEPK/proB	Q88Q07	160488	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	bacterial_glutamate_to_p5c_biosynthesis		bacterial_glutamate_to_p5c_biosynthesis:prob_glutamate_5_kinase	bacterial_nitrogen_regulatory_pts|coenzyme_a_biosynthesis|pseudomonad_cbr_crc_catabolite_control|sphingolipid_de_novo_synthesis	MODIFY
PSEPK/pvdD	Q88F79	160488	GO:0072330	monocarboxylic acid biosynthetic process	ARBA:ARBA00027175	ENTAILED	False	coenzyme_a_biosynthesis		coenzyme_a_biosynthesis:pps_activity		REMOVE
PSEPK/pydB	A0A140FWK2	160488	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	pyrimidine_degradation		pyrimidine_degradation:dpys_pydB_activity	phenylacetate_catabolism	KEEP_AS_NON_CORE
PSEPK/pydB	A0A140FWK2	160488	GO:0072529	pyrimidine-containing compound catabolic process	ARBA:ARBA00043307	ENTAILED	False	pyrimidine_degradation		pyrimidine_degradation:dpys_pydB_activity	phenylacetate_catabolism	ACCEPT
PSEPK/rbsB	Q88K38	160488	GO:0055085	transmembrane transport	ARBA:ARBA00027679	NOT_ENTAILED	False	bacterial_pst_phosphate_uptake|bacterial_sec_posttranslational_protein_export|bacterial_twin_arginine_translocation|bacterial_type_i_secretion|bacterial_type_ii_secretion				MODIFY
PSEPK/relA	Q88MB8	160488	GO:0015949	nucleobase-containing small molecule interconversion	ARBA:ARBA00088782	NOT_ENTAILED	False	purine_nucleotide_interconversion			bacterial_nitrogen_regulatory_pts|gpi_anchor_remodeling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
PSEPK/rhlE	Q88D48	160488	GO:0009266	response to temperature stimulus	ARBA:ARBA00026893	NO_MODULE	False				bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_nucleotide_excision_repair|bacterial_pst_phosphate_uptake|bacterial_rna_degradation|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secretion_appa	UNDECIDED
PSEPK/ruvA	Q88NJ1	160488	GO:0006974	DNA damage response	ARBA:ARBA00026271	ENTAILED	False	bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing		bacterial_recbcd_end_resection:recc_scaffold_activity|bacterial_ruvabc_holliday_junction_processing:ruva_binding_activity|bacterial_ruvabc_holliday_junction_processing:ruvb_motor_activity	methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
PSEPK/serA	Q88CM5	160488	GO:0006564	L-serine biosynthetic process	ARBA:ARBA00093701	ENTAILED	True	phosphorylated_serine_biosynthesis|serine_biosynthesis_one_carbon		phosphorylated_serine_biosynthesis:serA_activity|serine_biosynthesis_one_carbon:phgdh_activity	bacterial_beta_aryl_ether_dimer_cleavage|bacterial_sulfoquinovose_catabolism|complex_i_assembly_factors	ACCEPT
PSEPK/tatA-II	Q88D13	160488	GO:0065002	intracellular protein transmembrane transport	ARBA:ARBA00034583	NO_MODULE	False				bacterial_sec_posttranslational_protein_export|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_v_secretion|mitochondrial_complex_iii	ACCEPT
PSEPK/tauC	Q88RA2	160488	GO:0042918	alkanesulfonate transmembrane transport	ARBA:ARBA00034185	NOT_ENTAILED	False	taurine_biosynthesis_and_transport|taurine_uptake_and_desulfonation				MODIFY
PSEPK/tktA	Q88D62	160488	GO:0009052	pentose-phosphate shunt, non-oxidative branch	ARBA:ARBA00091353	ENTAILED	True	pentose_phosphate_nonoxidative_branch		pentose_phosphate_nonoxidative_branch:tkt_activity	bacterial_sulfoquinovose_catabolism|pentose_phosphate_pathway	ACCEPT
PSEPK/trpF	Q88LE0	160488	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	tryptophan_biosynthesis		tryptophan_biosynthesis:fused_prai_activity|tryptophan_biosynthesis:prai_activity	methylcitrate_cycle|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
PSEPK/ttgB	Q88N31	160488	GO:0009636	response to toxic substance	ARBA:ARBA00026669	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|methylglyoxal_detoxification			bacterial_type_i_secretion	MODIFY
PSEPK/ttgR	Q88N29	160488	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				bacterial_nonhomologous_end_joining|bacterial_recbcd_end_resection|crispr_cas_adaptive_immunity|pseudomonad_gac_lifestyle_phosphorelay	ACCEPT
PSEPK/ubiE	Q88D17	160488	GO:0042181	ketone biosynthetic process	ARBA:ARBA00027493	ENTAILED	False	ubiquinone_biosynthesis		ubiquinone_biosynthesis:c_methyltransferase_activity|ubiquinone_biosynthesis:coq5_c_methyltransferase_activity	methionine_cycle	TOO_GENERAL
PSEPK/uvrA	Q88QK7	160488	GO:0006974	DNA damage response	ARBA:ARBA00026271	ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection		bacterial_nucleotide_excision_repair:uvrb_activity|bacterial_nucleotide_excision_repair:uvrc_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_cytochrome_c_maturation_system_i|bacterial_lps_transport|bacterial_pst_phosphate_uptake|bacterial_type_ii_secretion|bacterial_type_iii_secretion_injectisome|bacterial_type_iv_secretion_apparatus|bacterial_type_vi_secretion_apparatus|coenzyme_q10_biosynthesis|crispr_cas_adaptive_immunity|gp	MARK_AS_OVER_ANNOTATED
PYRO7/PMK1	G4N0Z0	242507	GO:0075018	positive regulation of appressorium formation	ARBA:ARBA00088016	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SACEN/eryAI	A4F7N8	405948	GO:0033068	macrolide biosynthetic process	ARBA:ARBA00029207	ENTAILED	False	erythromycin_biosynthesis		erythromycin_biosynthesis:eryAIII_fn|erythromycin_biosynthesis:eryAII_fn|erythromycin_biosynthesis:eryAI_fn	alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization|bacterial_unsaturated_fatty_acid_biosynthesis|type_ii_fatty_acid_synthesis	ACCEPT
SACEN/eryAII	A4F7P0	405948	GO:0033068	macrolide biosynthetic process	ARBA:ARBA00029207	ENTAILED	False	erythromycin_biosynthesis		erythromycin_biosynthesis:eryAIII_fn|erythromycin_biosynthesis:eryAII_fn|erythromycin_biosynthesis:eryAI_fn|erythromycin_biosynthesis:eryBII_fn|erythromycin_biosynthesis:eryBIV_fn	alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization|bacterial_unsaturated_fatty_acid_biosynthesis|complex_i_assembly_factors|type_ii_fatty_acid_synthesis	ACCEPT
SACEN/eryAIII	A4F7P1	405948	GO:0033068	macrolide biosynthetic process	ARBA:ARBA00029207	ENTAILED	False	erythromycin_biosynthesis		erythromycin_biosynthesis:eryAIII_fn|erythromycin_biosynthesis:eryAII_fn|erythromycin_biosynthesis:eryAI_fn	alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization|bacterial_unsaturated_fatty_acid_biosynthesis|type_ii_fatty_acid_synthesis	ACCEPT
SACEN/eryBV	A4F7N6	405948	GO:0017000	antibiotic biosynthetic process	ARBA:ARBA00028144	ENTAILED	False	erythromycin_biosynthesis		erythromycin_biosynthesis:eryBV_fn|erythromycin_biosynthesis:eryCIII_fn	tres_mak_glge_branched_alpha_glucan_biosynthesis	ACCEPT
SACEN/eryCIII	A4F7P3	405948	GO:0017000	antibiotic biosynthetic process	ARBA:ARBA00028144	ENTAILED	False	erythromycin_biosynthesis		erythromycin_biosynthesis:eryBV_fn|erythromycin_biosynthesis:eryCIII_fn	tres_mak_glge_branched_alpha_glucan_biosynthesis	ACCEPT
SALRS/PTSG_11235	F2USU1	946362	GO:0035332	positive regulation of hippo signaling	ARBA:ARBA00091325	NO_MODULE	False				g2_m_transition|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
SCHJY/shc1	B6K412	402676	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	MODULE_INCOMPLETE	False	methylcitrate_cycle	methylcitrate_cycle:propionate_activation|methylcitrate_cycle:methylcitrate_synthesis|methylcitrate_cycle:methylisocitrate_formation|methylcitrate_cycle:methylisocitrate_cleavage	methylcitrate_cycle:prpF_aconitate_isomerase	phenylacetate_catabolism	MODIFY
SCHPO/SPAC1093.02	Q9UTQ1	284812	GO:0042816	vitamin B6 metabolic process	ARBA:ARBA00027956	ENTAILED	True	vitamin_b6_plp_metabolism		vitamin_b6_plp_metabolism:pnpo_activity	complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	KEEP_AS_NON_CORE
SCHPO/SPAC11D3.09	Q10088	284812	GO:0019627	urea metabolic process	ARBA:ARBA00047263	NOT_ENTAILED	False	urea_cycle|urease_biogenesis_urea_hydrolysis|ureide_urea_catabolism			phenylacetate_catabolism|polyamine_metabolism	KEEP_AS_NON_CORE
SCHPO/SPAC17A5.13	O13774	284812	GO:0009396	folic acid-containing compound biosynthetic process	ARBA:ARBA00029164	MODULE_INCOMPLETE	False	tetrahydrofolate_biosynthesis	tetrahydrofolate_biosynthesis:dihydroneopterin_dephosphorylation_step	tetrahydrofolate_biosynthesis:gtp_cyclohydrolase_i_activity	phenylacetate_catabolism|tetrahydrobiopterin_metabolism	ACCEPT
SCHPO/SPAC17G8.11c	Q10323	284812	GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process	ARBA:ARBA00089511	NO_MODULE	False					ACCEPT
SCHPO/SPAC1B3.01c	O13867	284812	GO:0006206	pyrimidine nucleobase metabolic process	ARBA:ARBA00086395	NOT_ENTAILED	False	pyrimidine_degradation|pyrimidine_nucleotide_catabolism			pyrimidine_salvage	KEEP_AS_NON_CORE
SCHPO/SPAC1B3.01c	O13867	284812	GO:0008655	pyrimidine-containing compound salvage	ARBA:ARBA00084547	MODULE_INCOMPLETE	True	pyrimidine_salvage	pyrimidine_salvage:cmp_kinase_step	pyrimidine_salvage:uracil_prt_activity		KEEP_AS_NON_CORE
SCHPO/SPAC22A12.10	O13901	284812	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	kennedy_pathway_phospholipid_synthesis		kennedy_pathway_phospholipid_synthesis:chpt_activity|kennedy_pathway_phospholipid_synthesis:ept_activity	sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/SPAC22A12.10	O13901	284812	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	kennedy_pathway_phospholipid_synthesis|sphingolipid_de_novo_synthesis		kennedy_pathway_phospholipid_synthesis:chpt_activity|kennedy_pathway_phospholipid_synthesis:ept_activity|sphingolipid_de_novo_synthesis:ipt1_activity		KEEP_AS_NON_CORE
SCHPO/SPAC3A11.07	O14121	284812	GO:0015980	energy derivation by oxidation of organic compounds	ARBA:ARBA00026991	MODULE_INCOMPLETE	False	mitochondrial_complex_i_core	mitochondrial_complex_i_core:complex_i_q_module	mitochondrial_complex_i_core:ndufv1_activity	complex_i_assembly_factors	KEEP_AS_NON_CORE
SCHPO/SPAC694.03	Q9P7T7	284812	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/SPAC6F6.11c	O14242	284812	GO:0042364	water-soluble vitamin biosynthetic process	ARBA:ARBA00029043	ENTAILED	False	vitamin_b6_plp_metabolism		vitamin_b6_plp_metabolism:pdxk_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/SPAC8E11.10	Q9Y6Z9	284812	GO:0005975	carbohydrate metabolic process	ARBA:ARBA00028487	NOT_ENTAILED	False	alginate_o_acetylation|alginate_polymerization_export|bacterial_cellulose_biosynthesis|emp_glycolysis|entner_doudoroff_and_gluconeogenesis			complex_i_assembly_factors	ACCEPT
SCHPO/SPAC8E11.10	Q9Y6Z9	284812	GO:0044281	small molecule metabolic process	ARBA:ARBA00028529	NOT_ENTAILED	False	2_aminoethylphosphonate_degradation|adp_heptose_biosynthesis|alginate_polymerization_export|arginine_biosynthesis|arginine_catabolism_arginase_pathway			complex_i_assembly_factors	ACCEPT
SCHPO/SPAPB24D3.03	Q9C0Y9	284812	GO:0019627	urea metabolic process	ARBA:ARBA00047263	NOT_ENTAILED	False	urea_cycle|urease_biogenesis_urea_hydrolysis|ureide_urea_catabolism			phenylacetate_catabolism|polyamine_metabolism	KEEP_AS_NON_CORE
SCHPO/SPBC12C2.07c	Q09741	284812	GO:0006596	polyamine biosynthetic process	ARBA:ARBA00026615	ENTAILED	True	polyamine_metabolism		polyamine_metabolism:sms_activity|polyamine_metabolism:spe4_activity|polyamine_metabolism:srm_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
SCHPO/SPBC12C2.11	Q09740	284812	GO:0006031	chitin biosynthetic process	ARBA:ARBA00084648	NO_MODULE	False				hexosamine_biosynthesis|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
SCHPO/SPBC2G5.05	Q9URM2	284812	GO:0006098	pentose-phosphate shunt	ARBA:ARBA00027507	ENTAILED	True	pentose_phosphate_nonoxidative_branch|pentose_phosphate_pathway		pentose_phosphate_nonoxidative_branch:tkt_activity|pentose_phosphate_pathway:transketolase_first_activity|pentose_phosphate_pathway:transketolase_second_activity		ACCEPT
SCHPO/SPBC660.16	P78812	284812	GO:0009051	pentose-phosphate shunt, oxidative branch	ARBA:ARBA00028372	ENTAILED	True	pentose_phosphate_oxidative_branch		pentose_phosphate_oxidative_branch:pgd_activity	complex_i_assembly_factors|pentose_phosphate_pathway	ACCEPT
SCHPO/SPBC8E4.03	O42887	284812	GO:0019627	urea metabolic process	ARBA:ARBA00047263	NOT_ENTAILED	False	urea_cycle|urease_biogenesis_urea_hydrolysis|ureide_urea_catabolism			phenylacetate_catabolism|polyamine_metabolism	KEEP_AS_NON_CORE
SCHPO/SPCC1672.03c	O14057	284812	GO:0046098	guanine metabolic process	ARBA:ARBA00090781	NO_MODULE	False				phenylacetate_catabolism|purine_nucleotide_catabolism|purine_salvage_and_catabolism	KEEP_AS_NON_CORE
SCHPO/SPCC18.10	O74860	284812	GO:0042364	water-soluble vitamin biosynthetic process	ARBA:ARBA00029043	ENTAILED	False	vitamin_b6_plp_metabolism		vitamin_b6_plp_metabolism:pdxk_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/SPCC18B5.05c	Q9USL6	284812	GO:0042364	water-soluble vitamin biosynthetic process	ARBA:ARBA00029043	ENTAILED	False	eukaryotic_thiamine_biosynthesis		eukaryotic_thiamine_biosynthesis:hmp_kinase_activity|eukaryotic_thiamine_biosynthesis:hmpp_kinase_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/SPCC364.07	P87228	284812	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	phosphorylated_serine_biosynthesis|serine_biosynthesis_one_carbon		phosphorylated_serine_biosynthesis:serA_activity|serine_biosynthesis_one_carbon:phgdh_activity	complex_i_assembly_factors	KEEP_AS_NON_CORE
SCHPO/SPCC364.07	P87228	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	phosphorylated_serine_biosynthesis|serine_biosynthesis_one_carbon		phosphorylated_serine_biosynthesis:serA_activity|serine_biosynthesis_one_carbon:phgdh_activity	complex_i_assembly_factors	KEEP_AS_NON_CORE
SCHPO/SPCC4F11.04c	Q9UT67	284812	GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process	ARBA:ARBA00089511	NO_MODULE	False					ACCEPT
SCHPO/ade1	P20772	284812	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purD_activity|de_novo_purine_synthesis:purM_activity		MARK_AS_OVER_ANNOTATED
SCHPO/ade1	P20772	284812	GO:0072521	purine-containing compound metabolic process	ARBA:ARBA00026860	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purD_activity|de_novo_purine_synthesis:purM_activity		MARK_AS_OVER_ANNOTATED
SCHPO/ade3	O14228	284812	GO:0006164	purine nucleotide biosynthetic process	ARBA:ARBA00026733	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purL_activity		ACCEPT
SCHPO/ade6	P15567	284812	GO:0006144	purine nucleobase metabolic process	ARBA:ARBA00084209	NOT_ENTAILED	True	purine_salvage_and_catabolism			de_novo_purine_synthesis|type_ii_fatty_acid_synthesis	MODIFY
SCHPO/ade7	Q9UUB4	284812	GO:0009152	purine ribonucleotide biosynthetic process	ARBA:ARBA00027685	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purC_activity	coenzyme_a_biosynthesis	ACCEPT
SCHPO/ade8	O60105	284812	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	ARBA:ARBA00027608	ENTAILED	False	de_novo_purine_synthesis|purine_nucleotide_interconversion		de_novo_purine_synthesis:purB_saicar_activity|purine_nucleotide_interconversion:adsl_amp_activity		ACCEPT
SCHPO/aga1	O94346	284812	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argA_activity|arginine_biosynthesis:argJ_initiating_activity|arginine_biosynthesis:argJ_recycling_activity|arginine_biosynthesis:fungal_nags_activity	alginate_o_acetylation|urea_cycle	MODIFY
SCHPO/aga1	O94346	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argA_activity|arginine_biosynthesis:argJ_initiating_activity|arginine_biosynthesis:argJ_recycling_activity|arginine_biosynthesis:fungal_nags_activity	alginate_o_acetylation|urea_cycle	MODIFY
SCHPO/apc2	Q874R3	284812	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False					ACCEPT
SCHPO/arg11	P31318	284812	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argB_activity|arginine_biosynthesis:argC1_activity|arginine_biosynthesis:argC2_activity	coenzyme_a_biosynthesis|complex_i_assembly_factors|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/arg11	P31318	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argB_activity|arginine_biosynthesis:argC1_activity|arginine_biosynthesis:argC2_activity	complex_i_assembly_factors|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/arg41	P50514	284812	GO:0000050	urea cycle	ARBA:ARBA00090240	ENTAILED	True	urea_cycle		urea_cycle:asl_activity	arginine_biosynthesis	MARK_AS_OVER_ANNOTATED
SCHPO/arg7	P40369	284812	GO:0000050	urea cycle	ARBA:ARBA00090240	ENTAILED	True	urea_cycle		urea_cycle:asl_activity	arginine_biosynthesis	MODIFY
SCHPO/ark1	O59790	284812	GO:0000819	sister chromatid segregation	ARBA:ARBA00026649	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/ark1	O59790	284812	GO:0008608	attachment of spindle microtubules to kinetochore	ARBA:ARBA00084444	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:0032465	regulation of cytokinesis	ARBA:ARBA00084247	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:0044779	meiotic spindle checkpoint signaling	ARBA:ARBA00085940	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:0045143	homologous chromosome segregation	ARBA:ARBA00092722	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:0072479	response to mitotic cell cycle spindle assembly checkpoint signaling	ARBA:ARBA00090474	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	ARBA:ARBA00087062	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/ark1	O59790	284812	GO:1902115	regulation of organelle assembly	ARBA:ARBA00033491	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
SCHPO/aro1	Q9P7R0	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	bacterial_shikimate_chorismate_biosynthesis|methionine_biosynthesis		bacterial_shikimate_chorismate_biosynthesis:aroa_epsp_synthase|bacterial_shikimate_chorismate_biosynthesis:arob_dehydroquinate_synthase|bacterial_shikimate_chorismate_biosynthesis:aroe_shikimate_dehydrogenase|bacterial_shikimate_chorismate_biosynthesis:arok_shikimate_kinase|bacterial_shikimate_chorismate_biosynthesis:arom_dhqase|bacterial_shikimate_chorismate_biosynthesis:arom_dhqs|bacterial_shikimate_chorismate_biosynthesis:arom_epsps|bacterial_shikimate_chorismate_biosynthesis:arom_sdh|bacterial_shikimate_chorismate_biosynthesis:arom_sk|bacterial_shikimate_chorismate_biosynthesis:aroq_dehydroquinase|bacterial_shikimate_chorismate_biosynthesis:type_i_dehydroquinase|methionine_biosynthesis:metZ_activity	complex_i_assembly_factors|methylcitrate_cycle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/aro3	Q9UT09	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	bacterial_shikimate_chorismate_biosynthesis|methionine_biosynthesis		bacterial_shikimate_chorismate_biosynthesis:aro_fgh_family_dahp_synthase|bacterial_shikimate_chorismate_biosynthesis:aroh_family_dahp_synthase|methionine_biosynthesis:metZ_activity		MODIFY
SCHPO/aro4	Q09755	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	bacterial_shikimate_chorismate_biosynthesis|methionine_biosynthesis		bacterial_shikimate_chorismate_biosynthesis:aro_fgh_family_dahp_synthase|bacterial_shikimate_chorismate_biosynthesis:aroh_family_dahp_synthase|methionine_biosynthesis:metZ_activity		MODIFY
SCHPO/aro7	O13739	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:chorismate_mutase	methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/aru1	Q10066	284812	GO:0006527	L-arginine catabolic process	ARBA:ARBA00085481	ENTAILED	True	arginine_catabolism_arginase_pathway		arginine_catabolism_arginase_pathway:arginase_activity	phenylacetate_catabolism|urea_cycle	ACCEPT
SCHPO/asp1	O74429	284812	GO:0030643	intracellular phosphate ion homeostasis	ARBA:ARBA00086651	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_a_biosynthesis|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|myo_inositol_and_inositol_phosphate_biosynthesis|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/asp1	O74429	284812	GO:0032958	inositol phosphate biosynthetic process	ARBA:ARBA00087455	MODULE_INCOMPLETE	True	myo_inositol_and_inositol_phosphate_biosynthesis	myo_inositol_and_inositol_phosphate_biosynthesis:myo_inositol_synthesis	myo_inositol_and_inositol_phosphate_biosynthesis:ip6k_activity|myo_inositol_and_inositol_phosphate_biosynthesis:ppip5k_activity	bacterial_nucleotide_excision_repair|coenzyme_a_biosynthesis|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/atg13	O36019	284812	GO:0000422	autophagy of mitochondrion	ARBA:ARBA00026840	NO_MODULE	False				sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/atg13	O36019	284812	GO:0016236	macroautophagy	ARBA:ARBA00027245	NO_MODULE	False				sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/bcp1	O94561	284812	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
SCHPO/caa1	O42652	284812	GO:0043490	malate-aspartate shuttle	ARBA:ARBA00043538	MODULE_INCOMPLETE	True	malate_aspartate_shuttle	malate_aspartate_shuttle:mas_carriers	malate_aspartate_shuttle:got1_activity|malate_aspartate_shuttle:got2_activity	aspartate_asparagine_metabolism|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
SCHPO/car1	P37818	284812	GO:0006527	L-arginine catabolic process	ARBA:ARBA00085481	ENTAILED	True	arginine_catabolism_arginase_pathway		arginine_catabolism_arginase_pathway:arginase_activity	phenylacetate_catabolism|urea_cycle	ACCEPT
SCHPO/cdc12	Q10059	284812	GO:1904498	protein localization to mitotic actomyosin contractile ring	ARBA:ARBA00090047	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
SCHPO/cdc15	Q09822	284812	GO:1903475	mitotic actomyosin contractile ring assembly	ARBA:ARBA00088916	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|n_glycan_llo_assembly_cytoplasmic|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	ACCEPT
SCHPO/cdc42	Q01112	284812	GO:0030010	establishment of cell polarity	ARBA:ARBA00086232	NO_MODULE	False				chylomicron_assembly_secretion|dolichol_phosphate_sugar_donor_supply|ergosterol_biosynthesis|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|oligosaccharyltransferase_complex|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|propionyl_coa_catabolism|pyr	ACCEPT
SCHPO/cgs1	P36600	284812	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/cis4	Q9HGQ3	284812	GO:0030003	intracellular monoatomic cation homeostasis	ARBA:ARBA00028070	NO_MODULE	False					MODIFY
SCHPO/cis4	Q9HGQ3	284812	GO:0098771	inorganic ion homeostasis	ARBA:ARBA00028888	NO_MODULE	False					MODIFY
SCHPO/clp1	Q9P7H1	284812	GO:0000278	mitotic cell cycle	ARBA:ARBA00028458	ENTAILED	False	g2_m_transition		g2_m_transition:cdc25_phosphatase|g2_m_transition:pp2a_b55	gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
SCHPO/clp1	Q9P7H1	284812	GO:0007096	regulation of exit from mitosis	ARBA:ARBA00092142	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
SCHPO/clp1	Q9P7H1	284812	GO:0032954	regulation of cytokinetic process	ARBA:ARBA00087459	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
SCHPO/clp1	Q9P7H1	284812	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/clr4	O60016	284812	GO:0030466	silent mating-type cassette heterochromatin formation	ARBA:ARBA00087185	NO_MODULE	False				bacterial_methionine_cycle|bacterial_recbcd_end_resection|complex_i_assembly_factors|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|methionine_cycle|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesi	ACCEPT
SCHPO/clr4	O60016	284812	GO:0031509	subtelomeric heterochromatin formation	ARBA:ARBA00085535	NO_MODULE	False				bacterial_methionine_cycle|bacterial_recbcd_end_resection|complex_i_assembly_factors|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|methionine_cycle|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesi	ACCEPT
SCHPO/clr4	O60016	284812	GO:0140727	siRNA-mediated pericentric heterochromatin formation	ARBA:ARBA00087565	NO_MODULE	False				bacterial_methionine_cycle|bacterial_recbcd_end_resection|complex_i_assembly_factors|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|methionine_cycle|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesi	ACCEPT
SCHPO/cnp1	Q9Y812	284812	GO:0006325	chromatin organization	ARBA:ARBA00028060	NO_MODULE	False				bacterial_recbcd_end_resection|complex_i_accessory_subunits|complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|vesicle_coat_budding	KEEP_AS_NON_CORE
SCHPO/coq5	P87230	284812	GO:0042181	ketone biosynthetic process	ARBA:ARBA00027493	ENTAILED	False	coenzyme_q10_biosynthesis		coenzyme_q10_biosynthesis:coq5_activity	methionine_cycle	KEEP_AS_NON_CORE
SCHPO/cps1	O13968	284812	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	NOT_ENTAILED	False	arginine_biosynthesis|arginine_catabolism_arginase_pathway|aspartate_asparagine_metabolism|aspartate_family_threonine_biosynthesis|bacterial_cysteine_biosynthesis_via_o_acetylserine			phenylacetate_catabolism|protease_activation_cascade	ACCEPT
SCHPO/cps1	O13968	284812	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	NOT_ENTAILED	False	adrenal_steroidogenesis|bacterial_unsaturated_fatty_acid_biosynthesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation			phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
SCHPO/cps1	O13968	284812	GO:0043604	amide biosynthetic process	ARBA:ARBA00028836	NO_MODULE	False				phenylacetate_catabolism|protease_activation_cascade	REMOVE
SCHPO/cps1	O13968	284812	GO:0043605	amide catabolic process	ARBA:ARBA00047244	NO_MODULE	False				phenylacetate_catabolism|protease_activation_cascade	MODIFY
SCHPO/cps1	O13968	284812	GO:1990845	adaptive thermogenesis	ARBA:ARBA00089174	NO_MODULE	False				phenylacetate_catabolism|protease_activation_cascade	REMOVE
SCHPO/crd1	O13899	284812	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:crd1_activity	phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/crd1	O13899	284812	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	cdp_dag_phospholipid_synthesis|sphingolipid_de_novo_synthesis		cdp_dag_phospholipid_synthesis:crd1_activity|sphingolipid_de_novo_synthesis:ipt1_activity	phenylacetate_catabolism	MODIFY
SCHPO/cta1	P55306	284812	GO:0000302	response to reactive oxygen species	ARBA:ARBA00027603	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|mitochondrial_complex_ii	KEEP_AS_NON_CORE
SCHPO/cta1	P55306	284812	GO:0042744	hydrogen peroxide catabolic process	ARBA:ARBA00088409	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|mitochondrial_complex_ii	ACCEPT
SCHPO/cul1	O13790	284812	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084384	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|vesicle_coat_budding	ACCEPT
SCHPO/cut1	P18296	284812	GO:0000280	nuclear division	ARBA:ARBA00028466	MODULE_INCOMPLETE	False	metaphase_anaphase_transition_and_mitotic_exit	metaphase_anaphase_transition_and_mitotic_exit:securin_separase_cohesin	metaphase_anaphase_transition_and_mitotic_exit:separase	phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
SCHPO/cut1	P18296	284812	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				metaphase_anaphase_transition_and_mitotic_exit|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
SCHPO/cut7	P24339	284812	GO:0000073	initial mitotic spindle pole body separation	ARBA:ARBA00090202	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/dcr1	Q09884	284812	GO:0010467	gene expression	ARBA:ARBA00028330	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	bacterial_recbcd_end_resection|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
SCHPO/dcr1	Q09884	284812	GO:0031047	regulatory ncRNA-mediated gene silencing	ARBA:ARBA00027536	NO_MODULE	False				bacterial_recbcd_end_resection|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
SCHPO/dps1	O43091	284812	GO:1901663	quinone biosynthetic process	ARBA:ARBA00026910	ENTAILED	False	coenzyme_q10_biosynthesis		coenzyme_q10_biosynthesis:pdss_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
SCHPO/eca39	O14370	284812	GO:0009082	branched-chain amino acid biosynthetic process	ARBA:ARBA00028438	ENTAILED	True	branched_chain_amino_acid_biosynthesis		branched_chain_amino_acid_biosynthesis:ilvE_activity	branched_chain_amino_acid_catabolism|ehrlich_pathway|ubiquinone_biosynthesis	ACCEPT
SCHPO/ecm31	Q09672	284812	GO:0072330	monocarboxylic acid biosynthetic process	ARBA:ARBA00027175	MODULE_INCOMPLETE	False	coenzyme_a_biosynthesis	coenzyme_a_biosynthesis:phosphopantetheine_adenylyltransferase_step	coenzyme_a_biosynthesis:panB_activity		MODIFY
SCHPO/erg1	Q9C1W3	284812	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	ENTAILED	False	ergosterol_biosynthesis|sterol_commitment_squalene_to_lanosterol		ergosterol_biosynthesis:erg1_activity|sterol_commitment_squalene_to_lanosterol:sqle_activity	complex_i_assembly_factors	MODIFY
SCHPO/erg26	O43050	284812	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg26_activity	cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors	ACCEPT
SCHPO/erg7	Q10231	284812	GO:0006694	steroid biosynthetic process	ARBA:ARBA00028726	ENTAILED	False	ergosterol_biosynthesis|sterol_commitment_squalene_to_lanosterol		ergosterol_biosynthesis:erg7_activity|sterol_commitment_squalene_to_lanosterol:lss_activity	methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
SCHPO/erg7	Q10231	284812	GO:1902653	secondary alcohol biosynthetic process	ARBA:ARBA00092559	ENTAILED	False	ergosterol_biosynthesis|sterol_commitment_squalene_to_lanosterol		ergosterol_biosynthesis:erg7_activity|sterol_commitment_squalene_to_lanosterol:lss_activity	methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/fas1	Q9UUG0	284812	GO:0042759	long-chain fatty acid biosynthetic process	ARBA:ARBA00034980	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_unsaturated_fatty_acid_biosynthesis|complex_i_assembly_factors|fatty_acid_de_novo_synthesis|gpi_anchor_remodeling|methylcitrate_cycle|phenylacetate_catabolism|type_ii_fatty_acid_synthesis	ACCEPT
SCHPO/ggg1	P87305	284812	GO:0006749	glutathione metabolic process	ARBA:ARBA00027824	ENTAILED	False	glutathione_synthesis_gamma_glutamyl_cycle		glutathione_synthesis_gamma_glutamyl_cycle:chac1_activity		KEEP_AS_NON_CORE
SCHPO/glo2	Q9UT36	284812	GO:0051596	methylglyoxal catabolic process	ARBA:ARBA00043291	ENTAILED	True	methylglyoxal_detoxification		methylglyoxal_detoxification:glo2_cytosolic_activity|methylglyoxal_detoxification:glo4_mitochondrial_activity|methylglyoxal_detoxification:gloB_activity	gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
SCHPO/glt1	Q9C102	284812	GO:0019676	ammonia assimilation cycle	ARBA:ARBA00086168	NO_MODULE	False				complex_i_assembly_factors|nitrogen_assimilation_glutamate_glutamine	ACCEPT
SCHPO/gpd1	P21696	284812	GO:0006114	glycerol biosynthetic process	ARBA:ARBA00084233	NO_MODULE	False				complex_i_assembly_factors|gluconeogenesis_human_substrates|glycerol_phosphate_shuttle|heat_shock_response	ACCEPT
SCHPO/gpd2	Q09845	284812	GO:0006114	glycerol biosynthetic process	ARBA:ARBA00084233	NO_MODULE	False				complex_i_assembly_factors|gluconeogenesis_human_substrates|glycerol_phosphate_shuttle|heat_shock_response	ACCEPT
SCHPO/hem1	O14092	284812	GO:0006783	heme biosynthetic process	ARBA:ARBA00027909	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:c4_alas_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
SCHPO/hem12	Q9USJ5	284812	GO:0006778	porphyrin-containing compound metabolic process	ARBA:ARBA00027898	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:urod_activity	type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
SCHPO/hem13	Q9UTE2	284812	GO:0006783	heme biosynthetic process	ARBA:ARBA00027909	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:hemf_activity	complex_i_assembly_factors|heat_shock_response	ACCEPT
SCHPO/hem3	Q09899	284812	GO:0006779	porphyrin-containing compound biosynthetic process	ARBA:ARBA00027896	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:hemc_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
SCHPO/hom3	O60163	284812	GO:0009090	L-homoserine biosynthetic process	ARBA:ARBA00091436	NO_MODULE	False				aspartate_family_threonine_biosynthesis|coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/hom3	O60163	284812	GO:0071266	'de novo' L-methionine biosynthetic process	ARBA:ARBA00092877	NOT_ENTAILED	True	methionine_biosynthesis			aspartate_family_threonine_biosynthesis|coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/hpt1	O13917	284812	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	ARBA:ARBA00027608	NOT_ENTAILED	False	de_novo_purine_synthesis|purine_nucleotide_interconversion			purine_salvage_and_catabolism	KEEP_AS_NON_CORE
SCHPO/hpt1	O13917	284812	GO:0106380	purine ribonucleotide salvage	ARBA:ARBA00090487	NO_MODULE	False				purine_salvage_and_catabolism	KEEP_AS_NON_CORE
SCHPO/hsp104	O94641	284812	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
SCHPO/hsp104	O94641	284812	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/hsp104	O94641	284812	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/hsp78	O74402	284812	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
SCHPO/hsp78	O74402	284812	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/hsp78	O74402	284812	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/idi1	Q10132	284812	GO:0050993	dimethylallyl diphosphate metabolic process	ARBA:ARBA00098399	ENTAILED	False	isoprenoid_diphosphate_biosynthesis		isoprenoid_diphosphate_biosynthesis:idi_activity	methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/imt1	O14084	284812	GO:0006673	inositol phosphoceramide metabolic process	ARBA:ARBA00043434	NO_MODULE	False				sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/imt1	O14084	284812	GO:0006688	glycosphingolipid biosynthetic process	ARBA:ARBA00043439	NOT_ENTAILED	True	glycosphingolipid_biosynthesis			sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/its3	O13853	284812	GO:0046854	phosphatidylinositol phosphate biosynthetic process	ARBA:ARBA00028323	ENTAILED	True	phosphoinositide_biosynthesis		phosphoinositide_biosynthesis:mss4_activity	coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/lys9	O59711	284812	GO:0009085	L-lysine biosynthetic process	ARBA:ARBA00028431	ENTAILED	True	lysine_biosynthesis_aminoadipate		lysine_biosynthesis_aminoadipate:saccharopine_reductase_activity	complex_i_assembly_factors|hydroxyproline_catabolism	ACCEPT
SCHPO/maa1	O94320	284812	GO:0043490	malate-aspartate shuttle	ARBA:ARBA00043538	MODULE_INCOMPLETE	True	malate_aspartate_shuttle	malate_aspartate_shuttle:mas_carriers	malate_aspartate_shuttle:got1_activity|malate_aspartate_shuttle:got2_activity	aspartate_asparagine_metabolism|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
SCHPO/mad2	O14417	284812	GO:0007094	mitotic spindle assembly checkpoint signaling	ARBA:ARBA00044419	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
SCHPO/mcs6	Q12126	284812	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ARBA:ARBA00033872	NO_MODULE	False				cell_cycle_progression|coenzyme_a_biosynthesis|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/met16	Q10270	284812	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction		aps_dependent_assimilatory_sulfate_reduction:paps_reductase_activity	complex_i_assembly_factors	MODIFY
SCHPO/met26	Q9UT19	284812	GO:0071265	L-methionine biosynthetic process	ARBA:ARBA00092883	ENTAILED	False	methionine_biosynthesis		methionine_biosynthesis:metE_activity|methionine_biosynthesis:metH_activity	bacterial_methionine_cycle|homocysteine_metabolism|methionine_cycle	ACCEPT
SCHPO/met3	O74314	284812	GO:0000096	sulfur amino acid metabolic process	ARBA:ARBA00028668	ENTAILED	False	fungal_sulfur_amino_acid_transsulfuration|methionine_biosynthesis		fungal_sulfur_amino_acid_transsulfuration:cystathionine_gamma_synthase_activity|methionine_biosynthesis:metB_activity|methionine_biosynthesis:metZ_activity		KEEP_AS_NON_CORE
SCHPO/mph1	O94235	284812	GO:0007094	mitotic spindle assembly checkpoint signaling	ARBA:ARBA00044419	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/mph1	O94235	284812	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/mst1	O94446	284812	GO:0120261	regulation of heterochromatin organization	ARBA:ARBA00095329	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	MODIFY
SCHPO/mst2	Q10325	284812	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	MODIFY
SCHPO/mst2	Q10325	284812	GO:0120261	regulation of heterochromatin organization	ARBA:ARBA00095329	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
SCHPO/mus81	P87231	284812	GO:0000712	resolution of meiotic recombination intermediates	ARBA:ARBA00090877	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
SCHPO/mus81	P87231	284812	GO:0000724	double-strand break repair via homologous recombination	ARBA:ARBA00027336	MODULE_INCOMPLETE	True	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_nucleotide_excision_repair|bacterial_ruvabc_holliday_junction_processing|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
SCHPO/mus81	P87231	284812	GO:0031297	replication fork processing	ARBA:ARBA00086530	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
SCHPO/ndk1	P49740	284812	GO:0009142	nucleoside triphosphate biosynthetic process	ARBA:ARBA00033837	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:udp_ndp_kinase_activity	coenzyme_a_biosynthesis|dntp_de_novo_synthesis|purine_nucleotide_interconversion|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/nip7	Q1MTQ9	284812	GO:1902626	assembly of large subunit precursor of preribosome	ARBA:ARBA00092444	NO_MODULE	False					ACCEPT
SCHPO/pab1	Q12702	284812	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	ARBA:ARBA00084549	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/pab1	Q12702	284812	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/pap1	Q01663	284812	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|heat_shock_response	ACCEPT
SCHPO/pcd1	Q09190	284812	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism	pyrimidine_nucleotide_catabolism:uridine_phosphorolysis|pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis|pyrimidine_nucleotide_catabolism:dihydropyrimidine_reduction|pyrimidine_nucleotide_catabolism:dihydropyrimidine_hydrolysis|pyrimidine_nucleotide_catabolism:ureidopropionase	pyrimidine_nucleotide_catabolism:cda_activity	heat_shock_response|phenylacetate_catabolism|pyrimidine_salvage	KEEP_AS_NON_CORE
SCHPO/pcd1	Q09190	284812	GO:0072527	pyrimidine-containing compound metabolic process	ARBA:ARBA00026859	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism|pyrimidine_salvage	pyrimidine_nucleotide_catabolism:uridine_phosphorolysis|pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis|pyrimidine_nucleotide_catabolism:dihydropyrimidine_reduction|pyrimidine_nucleotide_catabolism:dihydropyrimidine_hydrolysis|pyrimidine_nucleotide_catabolism:ureidopropionase|pyrimidine_salvage:cmp_kinase_step	pyrimidine_nucleotide_catabolism:cda_activity|pyrimidine_salvage:cytidine_deaminase_activity	heat_shock_response|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/pcd1	Q09190	284812	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			heat_shock_response|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism|pyrimidine_salvage	KEEP_AS_NON_CORE
SCHPO/pha2	O14361	284812	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:prephenate_dehydratase	methylcitrate_cycle	KEEP_AS_NON_CORE
SCHPO/pha2	O14361	284812	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:prephenate_dehydratase	methylcitrate_cycle	KEEP_AS_NON_CORE
SCHPO/pis1	Q10153	284812	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:pis1_activity	sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/pis1	Q10153	284812	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	cdp_dag_phospholipid_synthesis|sphingolipid_de_novo_synthesis		cdp_dag_phospholipid_synthesis:pis1_activity|sphingolipid_de_novo_synthesis:ipt1_activity		KEEP_AS_NON_CORE
SCHPO/plh1	O94680	284812	GO:0019915	lipid storage	ARBA:ARBA00028621	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|triacylglycerol_biosynthesis	ACCEPT
SCHPO/pli1	O94451	284812	GO:0007059	chromosome segregation	ARBA:ARBA00026830	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
SCHPO/pli1	O94451	284812	GO:0097240	chromosome attachment to the nuclear envelope	ARBA:ARBA00089802	NO_MODULE	False				alginate_o_acetylation	KEEP_AS_NON_CORE
SCHPO/ppc1	Q9USK7	284812	GO:0015937	coenzyme A biosynthetic process	ARBA:ARBA00026783	MODULE_INCOMPLETE	True	coenzyme_a_biosynthesis	coenzyme_a_biosynthesis:phosphopantetheine_adenylyltransferase_step	coenzyme_a_biosynthesis:coaB_activity|coenzyme_a_biosynthesis:ppcs_activity|coenzyme_a_biosynthesis:pps_activity		ACCEPT
SCHPO/ppk18	Q8TFG6	284812	GO:1901992	positive regulation of mitotic cell cycle phase transition	ARBA:ARBA00029089	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/pps1	O94584	284812	GO:0006659	phosphatidylserine biosynthetic process	ARBA:ARBA00087337	ENTAILED	True	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:cho1_activity	sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/psd1	O14333	284812	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:psd1_activity|cdp_dag_phospholipid_synthesis:psd2_activity	type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
SCHPO/psd3	O14111	284812	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:psd1_activity|cdp_dag_phospholipid_synthesis:psd2_activity	type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
SCHPO/puc1	P25009	284812	GO:0044843	cell cycle G1/S phase transition	ARBA:ARBA00026661	ENTAILED	False	g1_s_transition		g1_s_transition:g1_cyclin|g1_s_transition:g1s_cyclin	sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/puc1	P25009	284812	GO:0051726	regulation of cell cycle	ARBA:ARBA00029144	NOT_ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit			g1_s_transition|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/rad3	Q02099	284812	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	NOT_ENTAILED	False	erk5_cascade|gtpase_switch|jnk_cascade|mapk_relay|p38_cascade			coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/rbx1	O13959	284812	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|peroxisome-lifecycle|ubiquitin_transfer_relay	ACCEPT
SCHPO/rfc3	O14003	284812	GO:0070914	UV-damage excision repair	ARBA:ARBA00028029	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rfc3	O14003	284812	GO:1902983	DNA strand elongation involved in mitotic DNA replication	ARBA:ARBA00090648	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rhp51	P36601	284812	GO:0000723	telomere maintenance	ARBA:ARBA00027335	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/rhp51	P36601	284812	GO:0006312	mitotic recombination	ARBA:ARBA00028023	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rhp51	P36601	284812	GO:0007131	reciprocal meiotic recombination	ARBA:ARBA00028998	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/rhp51	P36601	284812	GO:0042148	DNA strand invasion	ARBA:ARBA00085980	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rpo41	O13993	284812	GO:0006390	mitochondrial transcription	ARBA:ARBA00086224	NO_MODULE	False				bacterial_recbcd_end_resection|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/rqh1	Q09811	284812	GO:0000724	double-strand break repair via homologous recombination	ARBA:ARBA00027336	MODULE_INCOMPLETE	True	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recb_motor_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_nucleotide_excision_repair|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rqh1	Q09811	284812	GO:0000729	DNA double-strand break processing	ARBA:ARBA00090881	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/rqh1	Q09811	284812	GO:0006312	mitotic recombination	ARBA:ARBA00028023	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
SCHPO/rqh1	Q09811	284812	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	ARBA:ARBA00085562	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
SCHPO/sid2	Q09898	284812	GO:0010564	regulation of cell cycle process	ARBA:ARBA00027431	MODULE_INCOMPLETE	False	metaphase_anaphase_transition_and_mitotic_exit	metaphase_anaphase_transition_and_mitotic_exit:securin_separase_cohesin	metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
SCHPO/sir1	Q1K9C2	284812	GO:0000103	sulfate assimilation	ARBA:ARBA00033980	ENTAILED	True	aps_dependent_assimilatory_sulfate_reduction		aps_dependent_assimilatory_sulfate_reduction:cysji_nadph_sulfite_reductase|aps_dependent_assimilatory_sulfate_reduction:met10_met5_nadph_sulfite_reductase	complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii	ACCEPT
SCHPO/slp1	P78972	284812	GO:0031145	anaphase-promoting complex-dependent catabolic process	ARBA:ARBA00034936	NO_MODULE	False				complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|metaphase_anaphase_transition_and_mitotic_exit|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/sod1	P28758	284812	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
SCHPO/spg1	P87027	284812	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	gtpase_switch		gtpase_switch:gtpase_activity	chylomicron_assembly_secretion|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|oligosaccharyltransferase_complex|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|propionyl_coa_catabolism|pyruvate_metabolism|urease_biogenesis_urea_hydrolysis|v	ACCEPT
SCHPO/spg1	P87027	284812	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False				chylomicron_assembly_secretion|ergosterol_biosynthesis|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|oligosaccharyltransferase_complex|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|propionyl_coa_catabolism|pyruvate_metabolism|urease_biogenesis_ure	ACCEPT
SCHPO/spm1	Q92398	284812	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	jnk_cascade|p38_cascade		jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/spt16	O94267	284812	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			cobalamin_intracellular_processing|complex_i_assembly_factors	KEEP_AS_NON_CORE
SCHPO/spt16	O94267	284812	GO:0034728	nucleosome organization	ARBA:ARBA00085234	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors	ACCEPT
SCHPO/ste9	O13286	284812	GO:0031145	anaphase-promoting complex-dependent catabolic process	ARBA:ARBA00034936	NO_MODULE	False				complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|metaphase_anaphase_transition_and_mitotic_exit|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/sua1	P78937	284812	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|paps_sulfate_activation		aps_dependent_assimilatory_sulfate_reduction:cysdn_atp_sulfurylase|aps_dependent_assimilatory_sulfate_reduction:met3_type_atp_sulfurylase|paps_sulfate_activation:papss_atp_sulfurylase	sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/swi6	P40381	284812	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NO_MODULE	False				bacterial_recbcd_end_resection|ergosterol_biosynthesis|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	KEEP_AS_NON_CORE
SCHPO/thi20	O94265	284812	GO:0042364	water-soluble vitamin biosynthetic process	ARBA:ARBA00029043	ENTAILED	False	eukaryotic_thiamine_biosynthesis		eukaryotic_thiamine_biosynthesis:hmp_kinase_activity|eukaryotic_thiamine_biosynthesis:hmpp_kinase_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/tim10	Q9UTE9	284812	GO:0045039	protein insertion into mitochondrial inner membrane	ARBA:ARBA00029129	NO_MODULE	False				cobalamin_intracellular_processing|complex_iv_assembly_factors	ACCEPT
SCHPO/tnr3	P41888	284812	GO:0042723	thiamine-containing compound metabolic process	ARBA:ARBA00028583	ENTAILED	False	eukaryotic_thiamine_biosynthesis		eukaryotic_thiamine_biosynthesis:tpk_activity	phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
SCHPO/tpx1	O74887	284812	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_accessory_subunits|complex_i_assembly_factors|complex_iv_assembly_factors|ergosterol_biosynthesis|glutathione_thioredoxin_redox_systems|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitocho	ACCEPT
SCHPO/trm402	O13935	284812	GO:0030488	tRNA methylation	ARBA:ARBA00028068	NO_MODULE	False				bacterial_methionine_cycle|methionine_cycle	ACCEPT
SCHPO/trx1	O14463	284812	GO:0045454	cell redox homeostasis	ARBA:ARBA00085337	ENTAILED	True	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:cytosolic_trx_activity	aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|electron_transfer_flavoprotein_system|ergosterol_biosynthesis|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|oligosaccharyltransf	ACCEPT
SCHPO/ups1	P87214	284812	GO:0006785	heme B biosynthetic process	ARBA:ARBA00093713	ENTAILED	True	heme_biosynthesis		heme_biosynthesis:hemd_activity	methylcitrate_cycle	ACCEPT
SCHPO/ura1	Q09794	284812	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	ENTAILED	False	de_novo_pyrimidine_synthesis|purine_nucleotide_interconversion		de_novo_pyrimidine_synthesis:aspartate_carbamoyltransferase_activity|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_glutaminase_component|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component|purine_nucleotide_interconversion:gmps_activity	arginine_biosynthesis|glutamate_glutamine_ammonia_hub|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|urea_cycle|vitamin_b6_plp_metabolism	MARK_AS_OVER_ANNOTATED
SCHPO/ura4	P14965	284812	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:omp_decarboxylase_activity	type_ii_fatty_acid_synthesis	MARK_AS_OVER_ANNOTATED
SCHPO/ura4	P14965	284812	GO:0072528	pyrimidine-containing compound biosynthetic process	ARBA:ARBA00026919	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:omp_decarboxylase_activity	type_ii_fatty_acid_synthesis	ACCEPT
SCHPO/ura5	O94331	284812	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ARBA:ARBA00086394	NO_MODULE	False				de_novo_pyrimidine_synthesis	ACCEPT
SCHPO/vas2	Q9P7N2	284812	GO:0010496	intercellular transport	ARBA:ARBA00092758	NO_MODULE	False				ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	REMOVE
SCHPO/wis1	P33886	284812	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SCHPO/wis1	P33886	284812	GO:0071470	cellular response to osmotic stress	ARBA:ARBA00027118	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
SOLHA/Cf-4	O50025	62890	GO:0050832	defense response to fungus	ARBA:ARBA00029244	NO_MODULE	False				chitin_perception|plant_nlr_resistosome_signaling	ACCEPT
SOLLC/PG2	P05117	4081	GO:0009830	cell wall modification involved in abscission	ARBA:ARBA00084907	NO_MODULE	False				phenylacetate_catabolism	MODIFY
SOLLC/PG2	P05117	4081	GO:0009901	anther dehiscence	ARBA:ARBA00084450	NO_MODULE	False				phenylacetate_catabolism	REMOVE
SOLLC/PG2	P05117	4081	GO:0010047	fruit dehiscence	ARBA:ARBA00091347	NO_MODULE	False				phenylacetate_catabolism	REMOVE
SOLLC/PR1B1	P04284	4081	GO:0098542	defense response to other organism	ARBA:ARBA00027395	NOT_ENTAILED	False	plant_nlr_resistosome_signaling				ACCEPT
SOLPI/CF-9	Q40235	4084	GO:0050832	defense response to fungus	ARBA:ARBA00029244	NO_MODULE	False					ACCEPT
SOLTU/CCOAOMT	Q8H9B6	4113	GO:0007623	circadian rhythm	ARBA:ARBA00027901	NO_MODULE	False				bacterial_methionine_cycle|methionine_cycle	REMOVE
STRCO/actI-ORF1	Q02059	100226	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	NOT_ENTAILED	True	fatty_acid_elongation_cycle			alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_lipoprotein_maturation|bacterial_mcl_pha_synthesis_and_mobilization|bacterial_unsaturated_fatty_acid_biosynthesis|type_ii_fatty_acid_synthesis	REMOVE
STRPU/Alx1	Q7Z0W3	7668	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|maternal_to_zygotic_transition|neural_ectoderm_anteroposterior_specification|notch_signaling|nrf_oxidative_stress_response|prim	MARK_AS_OVER_ANNOTATED
STRPU/Delta	Q8T4N9	7668	GO:0000902	cell morphogenesis	ARBA:ARBA00028811	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	REMOVE
STRPU/Delta	Q8T4N9	7668	GO:0042063	gliogenesis	ARBA:ARBA00086246	NOT_ENTAILED	False	nucleokinesis			gpcr_plc_calcium_pkc_signaling	REMOVE
STRPU/Delta	Q8T4N9	7668	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	MODIFY
THLAR/TFP	G1FNI6	13288	GO:0019760	glucosinolate metabolic process	ARBA:ARBA00043526	NOT_ENTAILED	False	aliphatic_glucosinolate_myrosinase_defense			heat_shock_response|sphingolipid_de_novo_synthesis	MODIFY
VIBCH/cds1	Q9KT44	243277	GO:1901605	alpha-amino acid metabolic process	ARBA:ARBA00026968	NO_MODULE	False				bacterial_cysteine_biosynthesis_via_o_acetylserine|methionine_biosynthesis	ACCEPT
XENLA/hes4-a	Q90Z12	8355	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/lin28a	Q8JHC4	8355	GO:0010629	negative regulation of gene expression	ARBA:ARBA00026647	NOT_ENTAILED	False	pirna_mediated_germline_silencing			early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	ACCEPT
XENLA/pax3-a	Q645N4	8355	GO:0008543	fibroblast growth factor receptor signaling pathway	ARBA:ARBA00084988	NOT_ENTAILED	True	fgfr_signaling			bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
XENLA/pax3-a	Q645N4	8355	GO:0014034	neural crest cell fate commitment	ARBA:ARBA00087933	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/pax3-a	Q645N4	8355	GO:0016055	Wnt signaling pathway	ARBA:ARBA00028830	ENTAILED	True	wnt_signaling		wnt_signaling:tcf_lef_factor	bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MARK_AS_OVER_ANNOTATED
XENLA/pax3-a	Q645N4	8355	GO:0048785	hatching gland development	ARBA:ARBA00090988	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	KEEP_AS_NON_CORE
XENLA/pou5f1.1	Q7T103	8355	GO:0001702	gastrulation with mouth forming second	ARBA:ARBA00089610	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	KEEP_AS_NON_CORE
XENLA/snai1	P19382	8355	GO:0001755	neural crest cell migration	ARBA:ARBA00089653	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/snai1	P19382	8355	GO:0014036	neural crest cell fate specification	ARBA:ARBA00087928	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/snai2	Q91924	8355	GO:0001755	neural crest cell migration	ARBA:ARBA00089653	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/snai2	Q91924	8355	GO:0014036	neural crest cell fate specification	ARBA:ARBA00087928	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	ACCEPT
XENLA/sox10	Q8AXX8	8355	GO:0014029	neural crest formation	ARBA:ARBA00027170	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MODIFY
XENLA/sox2	O42569	8355	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_transition|mitochondrial_upr|neural_ectoderm_anteropos	KEEP_AS_NON_CORE
XENLA/sox8	Q6VVD7	8355	GO:0014029	neural crest formation	ARBA:ARBA00027170	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MODIFY
XENLA/sox9-a	B7ZR65	8355	GO:0014029	neural crest formation	ARBA:ARBA00027170	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MODIFY
XENLA/zic1	O73689	8355	GO:0014029	neural crest formation	ARBA:ARBA00027170	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|g1_s_transition|germ_layer_specification|kit_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm	MODIFY
XENTR/F6WPT1	F6WPT1	8364	GO:1903292	protein localization to Golgi membrane	ARBA:ARBA00090371	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|urease_biogenesis_urea_hy	ACCEPT
human/A1CF	Q9NQ94	9606	GO:1902373	negative regulation of mRNA catabolic process	ARBA:ARBA00089345	NO_MODULE	False				apoptotic_execution_phase|ciliary_transition_zone|early_metazoan_development|egfr_signaling|ferroptosis|hedgehog_signaling|maternal_to_zygotic_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_com	MODIFY
human/ABCA1	O95477	9606	GO:0015850	organic hydroxy compound transport	ARBA:ARBA00027649	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			adrenal_steroidogenesis|bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|complex_i_assembly_factors|erbb2_signaling|hedgehog_signaling|intestinal_sterol_absorption_and_efflux|linc_complex|m	MODIFY
human/ABCA1	O95477	9606	GO:0045332	phospholipid translocation	ARBA:ARBA00026752	NO_MODULE	False				adrenal_steroidogenesis|bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|complex_i_assembly_factors|erbb2_signaling|hedgehog_signaling|intestinal_sterol_absorption_and_efflux|linc_complex|m	ACCEPT
human/ABCA3	Q99758	9606	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis			bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary	ACCEPT
human/ABCA4	P78363	9606	GO:0015850	organic hydroxy compound transport	ARBA:ARBA00027649	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|egfr_signaling|gtpase_switch|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|muth_independent_mismatch_repair|nlrp3_i	MODIFY
human/ABCA4	P78363	9606	GO:0045332	phospholipid translocation	ARBA:ARBA00026752	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|egfr_signaling|gtpase_switch|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|muth_independent_mismatch_repair|nlrp3_i	ACCEPT
human/ABCA7	Q8IZY2	9606	GO:0033344	cholesterol efflux	ARBA:ARBA00092042	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxi	KEEP_AS_NON_CORE
human/ABCA7	Q8IZY2	9606	GO:0033700	phospholipid efflux	ARBA:ARBA00084158	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxi	ACCEPT
human/ABCA7	Q8IZY2	9606	GO:0034205	amyloid-beta formation	ARBA:ARBA00090578	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxi	MODIFY
human/ABCA7	Q8IZY2	9606	GO:1902991	regulation of amyloid precursor protein catabolic process	ARBA:ARBA00090680	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_absorption_transport|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxi	ACCEPT
human/ABCB4	P21439	9606	GO:0045332	phospholipid translocation	ARBA:ARBA00026752	NO_MODULE	False				bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary	ACCEPT
human/ABCB7	O75027	9606	GO:0006879	intracellular iron ion homeostasis	ARBA:ARBA00035735	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ABCB7	O75027	9606	GO:0034755	iron ion transmembrane transport	ARBA:ARBA00043448	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MODIFY
human/ABCC6	O95255	9606	GO:0009410	response to xenobiotic stimulus	ARBA:ARBA00092608	MODULE_INCOMPLETE	False	phenylacetate_catabolism	phenylacetate_catabolism:phenylacetate_activation|phenylacetate_catabolism:phenylacetyl_coa_epoxidation|phenylacetate_catabolism:paaJ_thiolysis	phenylacetate_catabolism:paaZ_hydrolase	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/ABCC6	O95255	9606	GO:0046942	carboxylic acid transport	ARBA:ARBA00027271	NOT_ENTAILED	False	carnitine_shuttle|mitochondrial_dicarboxylate_tricarboxylate_carriers|mitochondrial_nucleotide_glycine_carriers			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ABCC8	Q09428	9606	GO:0050796	regulation of insulin secretion	ARBA:ARBA00091593	NO_MODULE	False				bacterial_nucleotide_excision_repair|bcl2_family_momp_control|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ABCC9	O60706	9606	GO:0033198	response to ATP	ARBA:ARBA00092810	NO_MODULE	False				bacterial_nucleotide_excision_repair|bcl2_family_momp_control|canonical_nlrp3_inflammasome|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|syn	ACCEPT
human/ABCC9	O60706	9606	GO:0071805	potassium ion transmembrane transport	ARBA:ARBA00028321	NO_MODULE	False				bacterial_nucleotide_excision_repair|bcl2_family_momp_control|canonical_nlrp3_inflammasome|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|syn	ACCEPT
human/ABCD1	P33897	9606	GO:0019217	regulation of fatty acid metabolic process	ARBA:ARBA00084953	NO_MODULE	False				bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bile_acid_synthesis_sidechain_conjugation|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|heat_shock_response|ketone_body_oxidation|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisomal_beta_oxidation|peroxi	KEEP_AS_NON_CORE
human/ABCD1	P33897	9606	GO:0045834	positive regulation of lipid metabolic process	ARBA:ARBA00086378	NO_MODULE	False				bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bile_acid_synthesis_sidechain_conjugation|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|heat_shock_response|ketone_body_oxidation|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisomal_beta_oxidation|peroxi	KEEP_AS_NON_CORE
human/ABCE1	P61221	9606	GO:0006412	translation	ARBA:ARBA00027100	NOT_ENTAILED	False	mitochondrial_trna_charging_and_initiator_formylation|selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|gtpase_switch|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|muth_independent_mismatch_repair|nlrp3_in	MARK_AS_OVER_ANNOTATED
human/ABCG8	Q9H221	9606	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis			adrenal_steroidogenesis|bacterial_nucleotide_excision_repair|chylomicron_assembly_secretion|cobalamin_intracellular_processing|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|metazoan_autophagosome_biogenesis|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_c	MODIFY
human/ABHD12	Q8N2K0	9606	GO:0006660	phosphatidylserine catabolic process	ARBA:ARBA00087338	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism|triacylglycerol_lipolysis	ACCEPT
human/ABL1	P00519	9606	GO:0002252	immune effector process	ARBA:ARBA00033862	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	MARK_AS_OVER_ANNOTATED
human/ABL1	P00519	9606	GO:0002429	immune response-activating cell surface receptor signaling pathway	ARBA:ARBA00089168	ENTAILED	False	tlr4_md2_lps_signaling		tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_tbk1	apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	MARK_AS_OVER_ANNOTATED
human/ABL1	P00519	9606	GO:0006909	phagocytosis	ARBA:ARBA00027650	ENTAILED	False	phagocytic_engulfment		phagocytic_engulfment:arp23_complex|phagocytic_engulfment:syk_fcgr_kinase	apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0007204	positive regulation of cytosolic calcium ion concentration	ARBA:ARBA00028136	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0010506	regulation of autophagy	ARBA:ARBA00043536	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	MARK_AS_OVER_ANNOTATED
human/ABL1	P00519	9606	GO:0010557	positive regulation of macromolecule biosynthetic process	ARBA:ARBA00027412	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	MARK_AS_OVER_ANNOTATED
human/ABL1	P00519	9606	GO:0010595	positive regulation of endothelial cell migration	ARBA:ARBA00092351	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0030100	regulation of endocytosis	ARBA:ARBA00085851	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0032956	regulation of actin cytoskeleton organization	ARBA:ARBA00028808	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	ACCEPT
human/ABL1	P00519	9606	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0045785	positive regulation of cell adhesion	ARBA:ARBA00026687	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0048008	platelet-derived growth factor receptor signaling pathway	ARBA:ARBA00090281	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:0051726	regulation of cell cycle	ARBA:ARBA00029144	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	KEEP_AS_NON_CORE
human/ABL1	P00519	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signalin	ACCEPT
human/ABR	Q12979	9606	GO:0007264	small GTPase-mediated signal transduction	ARBA:ARBA00044393	ENTAILED	True	gtpase_switch		gtpase_switch:gap_activity|gtpase_switch:gef_activity	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|egfr_signaling|fgfr_signaling|kit_signaling|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/ACACA	Q13085	9606	GO:0006637	acyl-CoA metabolic process	ARBA:ARBA00028700	ENTAILED	False	fatty_acid_de_novo_synthesis		fatty_acid_de_novo_synthesis:acc_activity	heat_shock_response|nlrp3_inflammasome|type_ii_fatty_acid_synthesis	MARK_AS_OVER_ANNOTATED
human/ACACB	O00763	9606	GO:0006637	acyl-CoA metabolic process	ARBA:ARBA00028700	ENTAILED	False	fatty_acid_de_novo_synthesis		fatty_acid_de_novo_synthesis:acc_activity	heat_shock_response|nlrp3_inflammasome|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
human/ACAD9	Q9H845	9606	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	fatty_acid_beta_oxidation		fatty_acid_beta_oxidation:mcad_activity|fatty_acid_beta_oxidation:vlcad_activity	ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphoty	MODIFY
human/ACADS	P16219	9606	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	ARBA:ARBA00085069	NO_MODULE	False				complex_i_assembly_factors|fatty_acid_beta_oxidation	ACCEPT
human/ACADSB	P45954	9606	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	fatty_acid_beta_oxidation		fatty_acid_beta_oxidation:mcad_activity|fatty_acid_beta_oxidation:scad_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|valine_isoleucine_distal_catabolism	KEEP_AS_NON_CORE
human/ACADSB	P45954	9606	GO:0046395	carboxylic acid catabolic process	ARBA:ARBA00027882	ENTAILED	False	fatty_acid_beta_oxidation|valine_isoleucine_distal_catabolism		fatty_acid_beta_oxidation:mcad_activity|fatty_acid_beta_oxidation:scad_activity|valine_isoleucine_distal_catabolism:acad8_activity|valine_isoleucine_distal_catabolism:acadsb_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/ACADVL	P49748	9606	GO:0006635	fatty acid beta-oxidation	ARBA:ARBA00028692	ENTAILED	True	fatty_acid_beta_oxidation		fatty_acid_beta_oxidation:mcad_activity|fatty_acid_beta_oxidation:vlcad_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle	ACCEPT
human/ACLY	P53396	9606	GO:0006637	acyl-CoA metabolic process	ARBA:ARBA00028700	ENTAILED	False	fatty_acid_de_novo_synthesis		fatty_acid_de_novo_synthesis:acly_activity	alginate_o_acetylation	KEEP_AS_NON_CORE
human/ACOX2	Q99424	9606	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	ARBA:ARBA00085031	ENTAILED	True	peroxisomal_beta_oxidation		peroxisomal_beta_oxidation:acox_activity	bile_acid_synthesis_sidechain_conjugation|complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle	ACCEPT
human/ACTR5	Q9H9F9	9606	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ACTR5	Q9H9F9	9606	GO:0033044	regulation of chromosome organization	ARBA:ARBA00029256	NOT_ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit			sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ACTR5	Q9H9F9	9606	GO:0051052	regulation of DNA metabolic process	ARBA:ARBA00027282	NO_MODULE	False				sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ACTR8	Q9H981	9606	GO:0033044	regulation of chromosome organization	ARBA:ARBA00029256	NOT_ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit			apoptotic_execution_phase|early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	KEEP_AS_NON_CORE
human/ACTR8	Q9H981	9606	GO:0051052	regulation of DNA metabolic process	ARBA:ARBA00027282	NO_MODULE	False				apoptotic_execution_phase|early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	KEEP_AS_NON_CORE
human/ADA	P00813	9606	GO:0006154	adenosine catabolic process	ARBA:ARBA00084293	NO_MODULE	False				phenylacetate_catabolism|purine_nucleotide_catabolism|purine_salvage_and_catabolism	ACCEPT
human/ADAM17	P78536	9606	GO:0006509	membrane protein ectodomain proteolysis	ARBA:ARBA00085430	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|glutathione_synthesis_gamma_glutamyl_cycle|hedgehog_signaling|mitochondrial_upr|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/ADAM17	P78536	9606	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	ARBA:ARBA00084350	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|glutathione_synthesis_gamma_glutamyl_cycle|hedgehog_signaling|mitochondrial_upr|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/ADGRA2	Q96PE1	9606	GO:0060070	canonical Wnt signaling pathway	ARBA:ARBA00026624	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	ACCEPT
human/ADGRV1	Q8WXG9	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False				apoptotic_execution_phase|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|sphingolipid_de_novo_synthesis	ACCEPT
human/ADGRV1	Q8WXG9	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cerebellum_development		cerebellum_development:gcp_smoothened_transducer	apoptotic_execution_phase|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|sphingolipid_de_novo_synthesis	MODIFY
human/ADGRV1	Q8WXG9	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				apoptotic_execution_phase|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ADGRV1	Q8WXG9	9606	GO:0050953	sensory perception of light stimulus	ARBA:ARBA00091469	NOT_ENTAILED	False	retinoid_visual_cycle			apoptotic_execution_phase|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ADPRS	Q9NX46	9606	GO:0071451	cellular response to superoxide	ARBA:ARBA00043602	NO_MODULE	False				gpi_anchor_remodeling|phenylacetate_catabolism	MODIFY
human/AGO1	Q9UL18	9606	GO:0031054	pre-miRNA processing	ARBA:ARBA00027506	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|maternal_to_zygotic_transition	ACCEPT
human/AGO1	Q9UL18	9606	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ARBA:ARBA00091152	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|maternal_to_zygotic_transition	ACCEPT
human/AGO1	Q9UL18	9606	GO:0070922	RISC complex assembly	ARBA:ARBA00086266	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|maternal_to_zygotic_transition	ACCEPT
human/AGO2	Q9UKV8	9606	GO:0070922	RISC complex assembly	ARBA:ARBA00086266	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|early_metazoan_development|er_unfolded_protein_response|ferroptosis|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	ACCEPT
human/AGO3	Q9H9G7	9606	GO:0031054	pre-miRNA processing	ARBA:ARBA00027506	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing	MARK_AS_OVER_ANNOTATED
human/AGO3	Q9H9G7	9606	GO:0070922	RISC complex assembly	ARBA:ARBA00086266	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|er_unfolded_protein_response|gpi_anchor_remodeling|maternal_to_zygotic_transition|phenylacetate_catabolism|pirna_mediated_germline_silencing	ACCEPT
human/AGO4	Q9HCK5	9606	GO:0031054	pre-miRNA processing	ARBA:ARBA00027506	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|er_unfolded_protein_response|maternal_to_zygotic_transition|pirna_mediated_germline_silencing	ACCEPT
human/AGO4	Q9HCK5	9606	GO:0070922	RISC complex assembly	ARBA:ARBA00086266	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|er_unfolded_protein_response|maternal_to_zygotic_transition|pirna_mediated_germline_silencing	ACCEPT
human/AGRN	O00468	9606	GO:0007010	cytoskeleton organization	ARBA:ARBA00026736	NOT_ENTAILED	False	nucleokinesis			canonical_nlrp3_inflammasome|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neurexin_transsynaptic_adhesion|nlr	KEEP_AS_NON_CORE
human/AGRN	O00468	9606	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			canonical_nlrp3_inflammasome|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neurexin_transsynaptic_adhesion|nlr	ACCEPT
human/AGRN	O00468	9606	GO:0050808	synapse organization	ARBA:ARBA00029184	ENTAILED	False	neurexin_transsynaptic_adhesion		neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity	canonical_nlrp3_inflammasome|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|primary_cilium_l	ACCEPT
human/AGRN	O00468	9606	GO:0061024	membrane organization	ARBA:ARBA00028824	ENTAILED	False	vesicle_coat_budding		vesicle_coat_budding:coat_activity	canonical_nlrp3_inflammasome|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neurexin_transsynaptic_adhesion|nlr	ACCEPT
human/AGRN	O00468	9606	GO:0099536	synaptic signaling	ARBA:ARBA00026596	ENTAILED	False	neurexin_transsynaptic_adhesion		neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity	canonical_nlrp3_inflammasome|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|primary_cilium_l	ACCEPT
human/AHR	P35869	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/AHR	P35869	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	MARK_AS_OVER_ANNOTATED
human/AHR	P35869	9606	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	ARBA:ARBA00035547	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/AICDA	Q9GZX7	9606	GO:0016445	somatic diversification of immunoglobulins	ARBA:ARBA00088467	NO_MODULE	False				apoptotic_execution_phase|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism	ACCEPT
human/AIFM1	O95831	9606	GO:0043068	positive regulation of programmed cell death	ARBA:ARBA00027743	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_	ACCEPT
human/AIRE	O43918	9606	GO:0002507	tolerance induction	ARBA:ARBA00088939	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|heat_shock_response|nlrp3_inflammasome	MODIFY
human/AIRE	O43918	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/AIRE	O43918	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/AK2	P54819	9606	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	purine_nucleotide_interconversion		purine_nucleotide_interconversion:adenylate_kinase_activity	sphingolipid_de_novo_synthesis	MODIFY
human/AK4P3	A0A8I5KW96	9606	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	de_novo_pyrimidine_synthesis|dntp_de_novo_synthesis|purine_nucleotide_interconversion		de_novo_pyrimidine_synthesis:udp_ndp_kinase_activity|dntp_de_novo_synthesis:dndp_kinase_activity|dntp_de_novo_synthesis:dtdp_ndp_kinase_activity|purine_nucleotide_interconversion:adenylate_kinase_activity|purine_nucleotide_interconversion:ndp_kinase_activity	sphingolipid_de_novo_synthesis	ACCEPT
human/AKR1C4	P17516	9606	GO:0008202	steroid metabolic process	ARBA:ARBA00027309	ENTAILED	False	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|sex_steroid_biosynthesis		bile_acid_biosynthesis:akr1c4_activity|cholesterol_synthesis_post_lanosterol:hsd17b7_activity|sex_steroid_biosynthesis:hsd17b3_activity	complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|ferroptosis|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|neural_ectoderm_anterop	ACCEPT
human/AKR1C4	P17516	9606	GO:0032787	monocarboxylic acid metabolic process	ARBA:ARBA00027288	ENTAILED	False	bile_acid_biosynthesis		bile_acid_biosynthesis:akr1c4_activity	cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|ferroptosis|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|neural_ectoderm_anterop	ACCEPT
human/AKR1C4	P17516	9606	GO:0042445	hormone metabolic process	ARBA:ARBA00028011	ENTAILED	False	sex_steroid_biosynthesis		sex_steroid_biosynthesis:hsd17b3_activity	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|ferroptosis|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial	ACCEPT
human/AKR1C8	Q5T2L2	9606	GO:0008202	steroid metabolic process	ARBA:ARBA00027309	NOT_ENTAILED	False	adrenal_steroidogenesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation|cholesterol_synthesis_post_lanosterol			complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/AKR1C8	Q5T2L2	9606	GO:0032787	monocarboxylic acid metabolic process	ARBA:ARBA00027288	NOT_ENTAILED	False	bacterial_pyruvate_metabolism|bacterial_unsaturated_fatty_acid_biosynthesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation			complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/AKR1C8	Q5T2L2	9606	GO:0042445	hormone metabolic process	ARBA:ARBA00028011	NOT_ENTAILED	False	adrenal_steroidogenesis|retinoid_visual_cycle|serotonin_melatonin_biosynthesis|sex_steroid_biosynthesis			complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/AKR1D1	P51857	9606	GO:0032787	monocarboxylic acid metabolic process	ARBA:ARBA00027288	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_ring_modification		bile_acid_biosynthesis:akr1d1_activity|bile_acid_synthesis_ring_modification:akr1d1_activity	complex_i_assembly_factors|primary_cilium_life_cycle	ACCEPT
human/AKR1D1	P51857	9606	GO:0042445	hormone metabolic process	ARBA:ARBA00028011	NOT_ENTAILED	False	adrenal_steroidogenesis|retinoid_visual_cycle|serotonin_melatonin_biosynthesis|sex_steroid_biosynthesis			bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|complex_i_assembly_factors|primary_cilium_life_cycle	ACCEPT
human/AKT1	P31749	9606	GO:0030335	positive regulation of cell migration	ARBA:ARBA00028907	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_s	KEEP_AS_NON_CORE
human/ALDH18A1	P54886	9606	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	proline_metabolism		proline_metabolism:aldh18a1_kinase_activity|proline_metabolism:aldh18a1_reductase_activity|proline_metabolism:monofunctional_gk_activity|proline_metabolism:monofunctional_gpr_activity	apoptotic_execution_phase|coenzyme_a_biosynthesis|complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
human/ALDOA	P04075	9606	GO:0006000	fructose metabolic process	ARBA:ARBA00043337	NOT_ENTAILED	False	fructolysis|fructose_pts_uptake_and_catabolism			apoptotic_execution_phase|emp_glycolysis|entner_doudoroff_and_gluconeogenesis|glycolysis_investment_phase|heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/ALDOA	P04075	9606	GO:0030388	fructose 1,6-bisphosphate metabolic process	ARBA:ARBA00087539	NO_MODULE	False				apoptotic_execution_phase|emp_glycolysis|entner_doudoroff_and_gluconeogenesis|glycolysis_investment_phase|heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle	ACCEPT
human/ALDOB	P05062	9606	GO:0030388	fructose 1,6-bisphosphate metabolic process	ARBA:ARBA00087539	NO_MODULE	False				ciliary_transition_zone|emp_glycolysis|entner_doudoroff_and_gluconeogenesis|fructolysis|glycolysis_investment_phase|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation	ACCEPT
human/ALG3	Q92685	9606	GO:0006487	protein N-linked glycosylation	ARBA:ARBA00085866	ENTAILED	True	n_glycan_llo_assembly_lumenal		n_glycan_llo_assembly_lumenal:alg3_activity		ACCEPT
human/ALPK2	Q86TB3	9606	GO:0003007	heart morphogenesis	ARBA:ARBA00086699	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/ALPK2	Q86TB3	9606	GO:0055013	cardiac muscle cell development	ARBA:ARBA00084678	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/ALX4	Q9H161	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_tran	ACCEPT
human/AMBRA1	Q9C0C7	9606	GO:0006914	autophagy	ARBA:ARBA00027757	ENTAILED	False	metazoan_autophagosome_biogenesis|mitophagy		metazoan_autophagosome_biogenesis:beclin_scaffold|mitophagy:fbxl4_receptor_degradation|mitophagy:fis1_adaptor|mitophagy:fis2_adaptor|mitophagy:optn_receptor	canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_response|nucleokinesis|oligosaccharyltransferase_complex|phagocy	MODIFY
human/AMH	P03971	9606	GO:0007548	sex differentiation	ARBA:ARBA00028749	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/AMIGO1	Q86WK6	9606	GO:1904064	positive regulation of cation transmembrane transport	ARBA:ARBA00087210	NO_MODULE	False					ACCEPT
human/AMPD1	P23109	9606	GO:0006753	nucleoside phosphate metabolic process	ARBA:ARBA00027937	ENTAILED	False	purine_nucleotide_catabolism|purine_nucleotide_interconversion		purine_nucleotide_catabolism:ampd_activity|purine_nucleotide_interconversion:ampd_activity	heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/AMPD2	Q01433	9606	GO:0006188	IMP biosynthetic process	ARBA:ARBA00084268	NOT_ENTAILED	False	de_novo_purine_synthesis			phenylacetate_catabolism|purine_nucleotide_catabolism|purine_nucleotide_interconversion	ACCEPT
human/AMPD2	Q01433	9606	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False				phenylacetate_catabolism|purine_nucleotide_catabolism|purine_nucleotide_interconversion	KEEP_AS_NON_CORE
human/AMPD2	Q01433	9606	GO:0106380	purine ribonucleotide salvage	ARBA:ARBA00090487	NO_MODULE	False				phenylacetate_catabolism|purine_nucleotide_catabolism|purine_nucleotide_interconversion	KEEP_AS_NON_CORE
human/AMPD3	Q01432	9606	GO:0006753	nucleoside phosphate metabolic process	ARBA:ARBA00027937	ENTAILED	False	purine_nucleotide_catabolism|purine_nucleotide_interconversion		purine_nucleotide_catabolism:ampd_activity|purine_nucleotide_interconversion:ampd_activity	phenylacetate_catabolism	ACCEPT
human/ANAPC11	Q9NYG5	9606	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|erbb2_signaling|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/ANAPC2	Q9UJX6	9606	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False					ACCEPT
human/ANK1	P16157	9606	GO:0048193	Golgi vesicle transport	ARBA:ARBA00028135	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial	ACCEPT
human/ANK1	P16157	9606	GO:0072657	protein localization to membrane	ARBA:ARBA00029167	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial	ACCEPT
human/ANK1	P16157	9606	GO:1990778	protein localization to cell periphery	ARBA:ARBA00027771	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial	ACCEPT
human/ANK2	Q01484	9606	GO:0072659	protein localization to plasma membrane	ARBA:ARBA00029169	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochond	ACCEPT
human/ANKRD11	Q6UB99	9606	GO:0048705	skeletal system morphogenesis	ARBA:ARBA00043345	NO_MODULE	False					KEEP_AS_NON_CORE
human/ANKRD11	Q6UB99	9606	GO:0060323	head morphogenesis	ARBA:ARBA00091413	NO_MODULE	False					KEEP_AS_NON_CORE
human/ANKRD11	Q6UB99	9606	GO:0060324	face development	ARBA:ARBA00091412	NO_MODULE	False					KEEP_AS_NON_CORE
human/ANKRD13A	Q8IZ07	9606	GO:0002091	negative regulation of receptor internalization	ARBA:ARBA00088001	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	MODIFY
human/ANKRD13B	Q86YJ7	9606	GO:0002091	negative regulation of receptor internalization	ARBA:ARBA00088001	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	MODIFY
human/ANKRD13D	Q6ZTN6	9606	GO:0002091	negative regulation of receptor internalization	ARBA:ARBA00088001	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	MODIFY
human/ANXA1	P04083	9606	GO:0031340	positive regulation of vesicle fusion	ARBA:ARBA00086235	NO_MODULE	False				apoptotic_execution_phase|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/ANXA1	P04083	9606	GO:0051051	negative regulation of transport	ARBA:ARBA00088037	NO_MODULE	False				apoptotic_execution_phase|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/AP2M1	Q96CW1	9606	GO:0031623	receptor internalization	ARBA:ARBA00087457	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|hedgehog_signaling|ldl_receptor_mediated_endocytosis|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagoso	ACCEPT
human/AP2M1	Q96CW1	9606	GO:0099003	vesicle-mediated transport in synapse	ARBA:ARBA00027531	ENTAILED	False	synaptic_vesicle_endocytosis		synaptic_vesicle_endocytosis:ap2_adaptor_complex|synaptic_vesicle_endocytosis:cme_ap2_route_marker|synaptic_vesicle_endocytosis:stonin2_synaptotagmin_adaptor	ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|hedgehog_signaling|ldl_receptor_mediated_endocytosis|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagoso	ACCEPT
human/AP3D1	O14617	9606	GO:0007041	lysosomal transport	ARBA:ARBA00033548	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/AP3D1	O14617	9606	GO:0010496	intercellular transport	ARBA:ARBA00092758	NO_MODULE	False				complex_i_assembly_factors	REMOVE
human/AP3D1	O14617	9606	GO:0016050	vesicle organization	ARBA:ARBA00028845	NOT_ENTAILED	False	snare_fusion_cycle|vesicle_coat_budding			complex_i_assembly_factors	KEEP_AS_NON_CORE
human/AP3D1	O14617	9606	GO:0032502	developmental process	ARBA:ARBA00028739	NOT_ENTAILED	False	body_axis_specification|cardiac_specification_network|cerebellum_development|early_metazoan_development|germ_layer_specification			complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/AP4B1	Q9Y6B7	9606	GO:0008104	intracellular protein localization	ARBA:ARBA00028253	NO_MODULE	False				synaptic_vesicle_endocytosis	ACCEPT
human/AP4E1	Q9UPM8	9606	GO:0008104	intracellular protein localization	ARBA:ARBA00028253	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/AP4E1	Q9UPM8	9606	GO:0045184	establishment of protein localization	ARBA:ARBA00027110	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/APAF1	O14727	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	NOT_ENTAILED	False	apoptotic_execution_phase|bcl2_family_momp_control			canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|necroptosis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	MODIFY
human/APAF1	O14727	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|necroptosis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/APAF1	O14727	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|necroptosis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/APC	P25054	9606	GO:0008285	negative regulation of cell population proliferation	ARBA:ARBA00027539	NO_MODULE	False				ciliary_transition_zone|complex_i_assembly_factors|metazoan_autophagosome_biogenesis|nucleokinesis|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/APC	P25054	9606	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False				ciliary_transition_zone|complex_i_assembly_factors|metazoan_autophagosome_biogenesis|nucleokinesis|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/APC2	O95996	9606	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False				ciliary_transition_zone|nucleokinesis|primary_cilium_life_cycle	ACCEPT
human/APH1A	Q96BI3	9606	GO:0006508	proteolysis	ARBA:ARBA00026291	NOT_ENTAILED	False	protease_activation_cascade|protein_prenylation_caax_processing			canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_c	MODIFY
human/APH1B	Q8WW43	9606	GO:0006508	proteolysis	ARBA:ARBA00026291	NOT_ENTAILED	False	protease_activation_cascade|protein_prenylation_caax_processing			canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_c	MODIFY
human/API5	Q9BZZ5	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|fgfr_signaling	ACCEPT
human/APLP1	P51693	9606	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			erbb2_signaling|heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/APLP1	P51693	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			erbb2_signaling|heat_shock_response|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/APOB	P04114	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	adrenal_steroidogenesis		adrenal_steroidogenesis:star_activity	canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|cobalamin_intracellular_processing|egfr_signaling|erbb2_signaling|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|synaptic_vesi	ACCEPT
human/APP	P05067	9606	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|mitochondrial_comp	MARK_AS_OVER_ANNOTATED
human/APP	P05067	9606	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|mitochondrial_comp	MARK_AS_OVER_ANNOTATED
human/APPL2	Q8NEU8	9606	GO:0006606	protein import into nucleus	ARBA:ARBA00028627	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/APPL2	Q8NEU8	9606	GO:0007179	transforming growth factor beta receptor signaling pathway	ARBA:ARBA00085361	NOT_ENTAILED	True	tgfb_smad_signaling			complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/APPL2	Q8NEU8	9606	GO:0042592	homeostatic process	ARBA:ARBA00027526	NOT_ENTAILED	False	glutathione_thioredoxin_redox_systems			complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	MARK_AS_OVER_ANNOTATED
human/APPL2	Q8NEU8	9606	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ARBA:ARBA00033889	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/AR	P10275	9606	GO:0033574	response to testosterone	ARBA:ARBA00085129	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_trans	ACCEPT
human/ARAF	P10398	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/ARFGEF1	Q9Y6D6	9606	GO:0006887	exocytosis	ARBA:ARBA00027178	NOT_ENTAILED	False	synaptic_vesicle_exocytosis			egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ARFGEF1	Q9Y6D6	9606	GO:0010256	endomembrane system organization	ARBA:ARBA00026889	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/ARFGEF2	Q9Y6D5	9606	GO:0010256	endomembrane system organization	ARBA:ARBA00026889	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/ARG1	P05089	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				arginine_catabolism_arginase_pathway|phenylacetate_catabolism|urea_cycle	KEEP_AS_NON_CORE
human/ARHGAP29	Q52LW3	9606	GO:0051056	regulation of small GTPase mediated signal transduction	ARBA:ARBA00027280	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gtpase_switch|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/ARHGEF3	Q9NR81	9606	GO:0051056	regulation of small GTPase mediated signal transduction	ARBA:ARBA00027280	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ARHGEF4	Q9NR80	9606	GO:0030032	lamellipodium assembly	ARBA:ARBA00086196	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ARHGEF4	Q9NR80	9606	GO:0046847	filopodium assembly	ARBA:ARBA00085124	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ARHGEF4	Q9NR80	9606	GO:0051056	regulation of small GTPase mediated signal transduction	ARBA:ARBA00027280	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/ARHGEF9	O43307	9606	GO:0051056	regulation of small GTPase mediated signal transduction	ARBA:ARBA00027280	NO_MODULE	False				egfr_signaling|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/ARL6	Q9H0F7	9606	GO:0061512	protein localization to cilium	ARBA:ARBA00091714	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/ARNT	P27540	9606	GO:0001666	response to hypoxia	ARBA:ARBA00027678	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
human/ARX	Q96QS3	9606	GO:0030182	neuron differentiation	ARBA:ARBA00027575	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/ASAH2	Q9NR71	9606	GO:0046512	sphingosine biosynthetic process	ARBA:ARBA00027422	NO_MODULE	False				glycosphingolipid_lysosomal_degradation|gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism|sphingosine_1_phosphate_rheostat	ACCEPT
human/ASAH2	Q9NR71	9606	GO:0046513	ceramide biosynthetic process	ARBA:ARBA00027419	NOT_ENTAILED	True	glycosphingolipid_biosynthesis|sphingolipid_de_novo_synthesis			glycosphingolipid_lysosomal_degradation|gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism|sphingosine_1_phosphate_rheostat	ACCEPT
human/ASAH2B	P0C7U1	9606	GO:0046512	sphingosine biosynthetic process	ARBA:ARBA00027422	NO_MODULE	False				glycosphingolipid_lysosomal_degradation|phenylacetate_catabolism|sphingosine_1_phosphate_rheostat	REMOVE
human/ASAH2B	P0C7U1	9606	GO:0046513	ceramide biosynthetic process	ARBA:ARBA00027419	NOT_ENTAILED	True	glycosphingolipid_biosynthesis|sphingolipid_de_novo_synthesis			glycosphingolipid_lysosomal_degradation|phenylacetate_catabolism|sphingosine_1_phosphate_rheostat	REMOVE
human/ASB2	Q96Q27	9606	GO:0055007	cardiac muscle cell differentiation	ARBA:ARBA00084649	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/ASPM	Q8IZT6	9606	GO:0007051	spindle organization	ARBA:ARBA00043498	NO_MODULE	False				phosphorylase_kinase_complex	ACCEPT
human/ASPRV1	Q53RT3	9606	GO:0016485	protein processing	ARBA:ARBA00028812	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	hedgehog_signaling|phenylacetate_catabolism	ACCEPT
human/ASTE1	Q2TB18	9606	GO:0006310	DNA recombination	ARBA:ARBA00028026	NOT_ENTAILED	False	bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/ATF4	P18848	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/ATF5	Q9Y2D1	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/ATF6	P18850	9606	GO:0036500	ATF6-mediated unfolded protein response	ARBA:ARBA00091677	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/ATF6	P18850	9606	GO:1903891	regulation of ATF6-mediated unfolded protein response	ARBA:ARBA00092211	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MODIFY
human/ATG12	O94817	9606	GO:0006914	autophagy	ARBA:ARBA00027757	ENTAILED	False	metazoan_autophagosome_biogenesis		metazoan_autophagosome_biogenesis:atg5_e3	alginate_o_acetylation	ACCEPT
human/ATG13	O75143	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ATG16L1	Q676U5	9606	GO:0034497	protein localization to phagophore assembly site	ARBA:ARBA00092844	NO_MODULE	False				alginate_o_acetylation|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_	ACCEPT
human/ATG5	Q9H1Y0	9606	GO:0043069	negative regulation of programmed cell death	ARBA:ARBA00027748	NO_MODULE	False				alginate_o_acetylation|metazoan_autophagosome_biogenesis	KEEP_AS_NON_CORE
human/ATG7	O95352	9606	GO:0009896	positive regulation of catabolic process	ARBA:ARBA00028093	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	ACCEPT
human/ATG7	O95352	9606	GO:0031667	response to nutrient levels	ARBA:ARBA00034581	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	ACCEPT
human/ATG7	O95352	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	KEEP_AS_NON_CORE
human/ATG7	O95352	9606	GO:0060255	regulation of macromolecule metabolic process	ARBA:ARBA00027781	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	KEEP_AS_NON_CORE
human/ATG7	O95352	9606	GO:0080090	regulation of primary metabolic process	ARBA:ARBA00026284	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	KEEP_AS_NON_CORE
human/ATL1	Q8WXF7	9606	GO:0016320	endoplasmic reticulum membrane fusion	ARBA:ARBA00093706	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_ves	ACCEPT
human/ATL1	Q8WXF7	9606	GO:1990809	endoplasmic reticulum tubular network membrane organization	ARBA:ARBA00093725	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_ves	ACCEPT
human/ATL3	Q6DD88	9606	GO:0016320	endoplasmic reticulum membrane fusion	ARBA:ARBA00093706	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_ves	ACCEPT
human/ATL3	Q6DD88	9606	GO:1990809	endoplasmic reticulum tubular network membrane organization	ARBA:ARBA00093725	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_ves	ACCEPT
human/ATM	Q13315	9606	GO:0000077	DNA damage checkpoint signaling	ARBA:ARBA00090214	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/ATM	Q13315	9606	GO:0000724	double-strand break repair via homologous recombination	ARBA:ARBA00027336	NOT_ENTAILED	True	bacterial_recbcd_end_resection			cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/ATM	Q13315	9606	GO:0007127	meiosis I	ARBA:ARBA00028964	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	UNDECIDED
human/ATM	Q13315	9606	GO:0010212	response to ionizing radiation	ARBA:ARBA00090590	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/ATM	Q13315	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	KEEP_AS_NON_CORE
human/ATM	Q13315	9606	GO:0032210	regulation of telomere maintenance via telomerase	ARBA:ARBA00047237	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/ATM	Q13315	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	KEEP_AS_NON_CORE
human/ATM	Q13315	9606	GO:0080135	regulation of cellular response to stress	ARBA:ARBA00026867	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	KEEP_AS_NON_CORE
human/ATM	Q13315	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/ATM	Q13315	9606	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	ARBA:ARBA00047255	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/ATOH1	Q92858	9606	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|cerebellum_development|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_tran	MARK_AS_OVER_ANNOTATED
human/ATP1A1	P05023	9606	GO:0006883	intracellular sodium ion homeostasis	ARBA:ARBA00086918	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|	ACCEPT
human/ATP1A1	P05023	9606	GO:0030007	intracellular potassium ion homeostasis	ARBA:ARBA00086105	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|	ACCEPT
human/ATP1A1	P05023	9606	GO:0036376	sodium ion export across plasma membrane	ARBA:ARBA00089462	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|	ACCEPT
human/ATP1A1	P05023	9606	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	ARBA:ARBA00098243	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|	MARK_AS_OVER_ANNOTATED
human/ATP1A1	P05023	9606	GO:1990573	potassium ion import across plasma membrane	ARBA:ARBA00090368	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|	ACCEPT
human/ATP1A2	P50993	9606	GO:0006942	regulation of striated muscle contraction	ARBA:ARBA00087049	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|ferroptosis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_	KEEP_AS_NON_CORE
human/ATP1A2	P50993	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	nlrp3_inflammasome|synaptic_vesicle_exocytosis		nlrp3_inflammasome:nlrp3_nacht_atp_switch|synaptic_vesicle_exocytosis:nsf_disassembly_atpase	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|ferroptosis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/ATP1A2	P50993	9606	GO:0008015	blood circulation	ARBA:ARBA00029044	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|ferroptosis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_	KEEP_AS_NON_CORE
human/ATP1A2	P50993	9606	GO:0008016	regulation of heart contraction	ARBA:ARBA00093015	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|ferroptosis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_	KEEP_AS_NON_CORE
human/ATP1A2	P50993	9606	GO:0030003	intracellular monoatomic cation homeostasis	ARBA:ARBA00028070	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|ferroptosis|gpi_anchor_remodeling|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_	ACCEPT
human/ATP1A3	P13637	9606	GO:0006883	intracellular sodium ion homeostasis	ARBA:ARBA00086918	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ATP1A3	P13637	9606	GO:0030007	intracellular potassium ion homeostasis	ARBA:ARBA00086105	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ATP1A3	P13637	9606	GO:0036376	sodium ion export across plasma membrane	ARBA:ARBA00089462	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ATP1A3	P13637	9606	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	ARBA:ARBA00098243	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/ATP1A3	P13637	9606	GO:1990573	potassium ion import across plasma membrane	ARBA:ARBA00090368	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ATP2B2	Q01814	9606	GO:1903779	regulation of cardiac conduction	ARBA:ARBA00091800	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	UNDECIDED
human/ATP6V0D1	P61421	9606	GO:0042592	homeostatic process	ARBA:ARBA00027526	NOT_ENTAILED	False	glutathione_thioredoxin_redox_systems			canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|mitochondrial_complex_v|nlrp3_inflammasome|phagosome_maturation|sphingolipid_de_novo_synthesis|synaptic_vesicle_cycle|synaptic_vesicle_neurotransmitter_loading	MARK_AS_OVER_ANNOTATED
human/ATP6V1A	P38606	9606	GO:0042592	homeostatic process	ARBA:ARBA00027526	NOT_ENTAILED	False	glutathione_thioredoxin_redox_systems			bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|linc_complex|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phagosome_maturation|phenylacetate_catabolism|primary_cilium	MARK_AS_OVER_ANNOTATED
human/ATP7B	P35670	9606	GO:0046688	response to copper ion	ARBA:ARBA00092178	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|cuproptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/ATRX	P46100	9606	GO:0010564	regulation of cell cycle process	ARBA:ARBA00027431	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:cohesin_kleisin	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|ciliary_transition_zone|coenzyme_q10_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|mitophagy|muth_independent_mismatch_repair|necroptosis|nlrp3_in	KEEP_AS_NON_CORE
human/ATRX	P46100	9606	GO:0033044	regulation of chromosome organization	ARBA:ARBA00029256	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:cohesin_kleisin	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|ciliary_transition_zone|coenzyme_q10_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|mitophagy|muth_independent_mismatch_repair|necroptosis|nlrp3_in	KEEP_AS_NON_CORE
human/ATRX	P46100	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|ciliary_transition_zone|coenzyme_q10_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|muth_i	KEEP_AS_NON_CORE
human/ATXN10	Q9UBB4	9606	GO:0120036	plasma membrane bounded cell projection organization	ARBA:ARBA00028051	NOT_ENTAILED	False	ciliary_transition_zone|intraflagellar_transport|primary_cilium_life_cycle				KEEP_AS_NON_CORE
human/AUH	Q13825	9606	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	ENTAILED	False	leucine_catabolism		leucine_catabolism:auh_activity|leucine_catabolism:liuC_activity	apoptotic_execution_phase|early_metazoan_development|fatty_acid_beta_oxidation|maternal_to_zygotic_transition|methylcitrate_cycle|peroxisomal_beta_oxidation|phenylacetate_catabolism|primordial_germ_cell_specification	MODIFY
human/AUH	Q13825	9606	GO:0170035	obsolete L-amino acid catabolic process	ARBA:ARBA00044574	NO_MODULE	False				apoptotic_execution_phase|early_metazoan_development|fatty_acid_beta_oxidation|leucine_catabolism|maternal_to_zygotic_transition|methylcitrate_cycle|peroxisomal_beta_oxidation|phenylacetate_catabolism|primordial_germ_cell_specification	MODIFY
human/AURKA	O14965	9606	GO:0007051	spindle organization	ARBA:ARBA00043498	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|m	ACCEPT
human/AURKA	O14965	9606	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|m	ACCEPT
human/AURKB	Q96GD4	9606	GO:0007051	spindle organization	ARBA:ARBA00043498	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/AURKB	Q96GD4	9606	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/AURKC	Q9UQB9	9606	GO:0007051	spindle organization	ARBA:ARBA00043498	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	UNDECIDED
human/AURKC	Q9UQB9	9606	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/AXIN1	O15169	9606	GO:0030178	negative regulation of Wnt signaling pathway	ARBA:ARBA00027587	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|mitophagy|necroptosis|n	ACCEPT
human/B3GALNT1	O75752	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b3galnt1_activity		KEEP_AS_NON_CORE
human/B3GALT6	Q96L58	9606	GO:0006024	glycosaminoglycan biosynthetic process	ARBA:ARBA00027325	NOT_ENTAILED	False	d_amino_acid_cell_wall_precursor_supply|gram_negative_lipoprotein_peptidoglycan_tether_remodeling|peptidoglycan_precursor_biosynthesis				ACCEPT
human/B3GNT5	Q9BYG0	9606	GO:0030148	sphingolipid biosynthetic process	ARBA:ARBA00027455	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b3gnt5_activity		KEEP_AS_NON_CORE
human/B3GNT5	Q9BYG0	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b3gnt5_activity		KEEP_AS_NON_CORE
human/B4GALNT1	Q00973	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b4galnt1_activity		MODIFY
human/B4GALT5	O43286	9606	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b4galt56_activity		MARK_AS_OVER_ANNOTATED
human/B4GALT6	Q9UBX8	9606	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	ENTAILED	False	glycosphingolipid_biosynthesis		glycosphingolipid_biosynthesis:b4galt56_activity		KEEP_AS_NON_CORE
human/BAAT	Q14032	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation|gpi_anchor_remodeling		bile_acid_biosynthesis:baat_activity|bile_acid_synthesis_sidechain_conjugation:baat_activity|gpi_anchor_remodeling:pgap1_activity|gpi_anchor_remodeling:pgap3_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/BAAT	Q14032	9606	GO:0032787	monocarboxylic acid metabolic process	ARBA:ARBA00027288	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation		bile_acid_biosynthesis:baat_activity|bile_acid_synthesis_sidechain_conjugation:baat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling	KEEP_AS_NON_CORE
human/BACE2	Q9Y5Z0	9606	GO:0006509	membrane protein ectodomain proteolysis	ARBA:ARBA00085430	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/BAG1	Q99933	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				heat_shock_response|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/BAG2	O95816	9606	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	ACCEPT
human/BAG2	O95816	9606	GO:0051247	positive regulation of protein metabolic process	ARBA:ARBA00028881	NO_MODULE	False				heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/BAG3	O95817	9606	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			ciliary_transition_zone|cobalamin_intracellular_processing|complex_i_assembly_factors|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligos	ACCEPT
human/BAG3	O95817	9606	GO:0010664	negative regulation of striated muscle cell apoptotic process	ARBA:ARBA00092005	NO_MODULE	False				ciliary_transition_zone|cobalamin_intracellular_processing|complex_i_assembly_factors|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligos	KEEP_AS_NON_CORE
human/BAG3	O95817	9606	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				ciliary_transition_zone|cobalamin_intracellular_processing|complex_i_assembly_factors|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligos	ACCEPT
human/BAG3	O95817	9606	GO:0097191	extrinsic apoptotic signaling pathway	ARBA:ARBA00028297	NO_MODULE	False				ciliary_transition_zone|cobalamin_intracellular_processing|complex_i_assembly_factors|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligos	KEEP_AS_NON_CORE
human/BAK1	Q16611	9606	GO:0032469	endoplasmic reticulum calcium ion homeostasis	ARBA:ARBA00084258	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/BAK1	Q16611	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	MODIFY
human/BAK1	Q16611	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	REMOVE
human/BAK1	Q16611	9606	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	REMOVE
human/BAK1	Q16611	9606	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ARBA:ARBA00092512	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/BAK1	Q16611	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	REMOVE
human/BAK1	Q16611	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				bcl2_family_momp_control|canonical_nlrp3_inflammasome|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	MODIFY
human/BAP1	Q92560	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|phenylacetate_catabolism|protease_activation_cascade	MODIFY
human/BAX	Q07812	9606	GO:0001836	release of cytochrome c from mitochondria	ARBA:ARBA00091670	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	ACCEPT
human/BAX	Q07812	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:hsp12_6_shsp	bcl2_family_momp_control|ferroptosis|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	REMOVE
human/BAX	Q07812	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	MODIFY
human/BAX	Q07812	9606	GO:0043523	regulation of neuron apoptotic process	ARBA:ARBA00085497	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	MARK_AS_OVER_ANNOTATED
human/BAX	Q07812	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	REMOVE
human/BAX	Q07812	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle	MODIFY
human/BBS1	Q8NFJ9	9606	GO:0001895	retina homeostasis	ARBA:ARBA00091684	NO_MODULE	False				erbb2_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/BBS1	Q8NFJ9	9606	GO:0008104	intracellular protein localization	ARBA:ARBA00028253	NO_MODULE	False				erbb2_signaling|wnt_signaling	MODIFY
human/BBS4	Q96RK4	9606	GO:0000226	microtubule cytoskeleton organization	ARBA:ARBA00028425	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|primary_cilium	KEEP_AS_NON_CORE
human/BBS4	Q96RK4	9606	GO:0007600	sensory perception	ARBA:ARBA00027936	NOT_ENTAILED	False	retinoid_visual_cycle			ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	KEEP_AS_NON_CORE
human/BBS4	Q96RK4	9606	GO:0061512	protein localization to cilium	ARBA:ARBA00091714	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/BCAT2	O15382	9606	GO:0009082	branched-chain amino acid biosynthetic process	ARBA:ARBA00028438	MODULE_INCOMPLETE	True	branched_chain_amino_acid_biosynthesis	branched_chain_amino_acid_biosynthesis:ilvIH_step|branched_chain_amino_acid_biosynthesis:ilvC_step|branched_chain_amino_acid_biosynthesis:ilvD_step|branched_chain_amino_acid_biosynthesis:leucine_extension	branched_chain_amino_acid_biosynthesis:ilvE_activity	branched_chain_amino_acid_catabolism|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
human/BCAT2	O15382	9606	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	ENTAILED	True	branched_chain_amino_acid_catabolism		branched_chain_amino_acid_catabolism:bcat2_activity	branched_chain_amino_acid_biosynthesis|ubiquinone_biosynthesis	ACCEPT
human/BCL11A	Q9H165	9606	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|hedgehog_signaling|kit_s	ACCEPT
human/BCL11B	Q9C0K0	9606	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/BCL2	P10415	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	ACCEPT
human/BCL2	P10415	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	ACCEPT
human/BCL2L1	Q07817	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response|nlrp3_inflammasome		heat_shock_response:hsp12_6_shsp|nlrp3_inflammasome:pycard_self_oligomerization	bcl2_family_momp_control|metazoan_autophagosome_biogenesis	MARK_AS_OVER_ANNOTATED
human/BCL2L1	Q07817	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				bcl2_family_momp_control|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	ACCEPT
human/BCL2L1	Q07817	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				bcl2_family_momp_control|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/BCL2L1	Q07817	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				bcl2_family_momp_control|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/BCL2L1	Q07817	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				bcl2_family_momp_control|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	ACCEPT
human/BCS1L	Q9Y276	9606	GO:0034551	mitochondrial respiratory chain complex III assembly	ARBA:ARBA00092360	NOT_ENTAILED	True	mitochondrial_complex_iii			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/BECN1	Q14457	9606	GO:0032801	receptor catabolic process	ARBA:ARBA00085467	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturati	ACCEPT
human/BECN2	A8MW95	9606	GO:0032801	receptor catabolic process	ARBA:ARBA00085467	NO_MODULE	False				ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphoty	ACCEPT
human/BID	P55957	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|er_unfolded_protein_response|heat_shock_response			erbb2_signaling	MARK_AS_OVER_ANNOTATED
human/BID	P55957	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|er_unfolded_protein_response|erk5_cascade|gtpase_switch			erbb2_signaling	MARK_AS_OVER_ANNOTATED
human/BID	P55957	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				erbb2_signaling	MARK_AS_OVER_ANNOTATED
human/BID	P55957	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				erbb2_signaling	MODIFY
human/BIN1	O00499	9606	GO:0006897	endocytosis	ARBA:ARBA00027119	ENTAILED	False	phagocytic_engulfment|synaptic_vesicle_endocytosis		phagocytic_engulfment:arp23_complex|synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	apoptotic_execution_phase|complex_i_assembly_factors|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/BIN1	O00499	9606	GO:0051649	establishment of localization in cell	ARBA:ARBA00028679	ENTAILED	False	synaptic_vesicle_endocytosis		synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	apoptotic_execution_phase|complex_i_assembly_factors|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/BIRC5	O15392	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|ciliary_transition_zone|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_ii|nlrp3_inflammasome|nucleokinesis|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/BIRC6	Q9NR09	9606	GO:0016567	protein ubiquitination	ARBA:ARBA00027966	ENTAILED	True	ubiquitin_transfer_relay		ubiquitin_transfer_relay:e2_activity	alginate_o_acetylation|apoptotic_execution_phase|metaphase_anaphase_transition_and_mitotic_exit|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
human/BIRC6	Q9NR09	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|metaphase_anaphase_transition_and_mitotic_exit|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/BIRC6	Q9NR09	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|metaphase_anaphase_transition_and_mitotic_exit|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/BLM	P54132	9606	GO:0000723	telomere maintenance	ARBA:ARBA00027335	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylac	ACCEPT
human/BLM	P54132	9606	GO:0000724	double-strand break repair via homologous recombination	ARBA:ARBA00027336	MODULE_INCOMPLETE	True	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:reca_tail_binding|bacterial_recbcd_end_resection:recb_motor_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium	ACCEPT
human/BLM	P54132	9606	GO:0031297	replication fork processing	ARBA:ARBA00086530	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylac	ACCEPT
human/BLM	P54132	9606	GO:0032392	DNA geometric change	ARBA:ARBA00027691	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylac	ACCEPT
human/BLM	P54132	9606	GO:0045910	negative regulation of DNA recombination	ARBA:ARBA00086129	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylac	ACCEPT
human/BLVRB	P30043	9606	GO:0030219	megakaryocyte differentiation	ARBA:ARBA00085624	NO_MODULE	False				complex_i_assembly_factors|heme_degradation|hydroxyproline_catabolism	KEEP_AS_NON_CORE
human/BMP10	O95393	9606	GO:0010611	regulation of cardiac muscle hypertrophy	ARBA:ARBA00091898	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP10	O95393	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	MODIFY
human/BMP10	O95393	9606	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	ARBA:ARBA00027948	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/BMP4	P12644	9606	GO:0001649	osteoblast differentiation	ARBA:ARBA00089865	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0002573	myeloid leukocyte differentiation	ARBA:ARBA00088984	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	UNDECIDED
human/BMP4	P12644	9606	GO:0003007	heart morphogenesis	ARBA:ARBA00086699	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0003129	heart induction	ARBA:ARBA00088459	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	UNDECIDED
human/BMP4	P12644	9606	GO:0021537	telencephalon development	ARBA:ARBA00084940	NOT_ENTAILED	False	nucleokinesis			canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0022408	negative regulation of cell-cell adhesion	ARBA:ARBA00092663	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	UNDECIDED
human/BMP4	P12644	9606	GO:0030501	positive regulation of bone mineralization	ARBA:ARBA00086906	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0030858	positive regulation of epithelial cell differentiation	ARBA:ARBA00088239	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0048662	negative regulation of smooth muscle cell proliferation	ARBA:ARBA00091356	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	UNDECIDED
human/BMP4	P12644	9606	GO:0060391	positive regulation of SMAD protein signal transduction	ARBA:ARBA00090778	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/BMP4	P12644	9606	GO:0060426	lung vasculature development	ARBA:ARBA00090964	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0060441	epithelial tube branching involved in lung morphogenesis	ARBA:ARBA00091049	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0060537	muscle tissue development	ARBA:ARBA00090616	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0061036	positive regulation of cartilage development	ARBA:ARBA00090328	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	UNDECIDED
human/BMP4	P12644	9606	GO:0071773	cellular response to BMP stimulus	ARBA:ARBA00085410	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	ARBA:ARBA00087293	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:1900745	positive regulation of p38MAPK cascade	ARBA:ARBA00085720	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP4	P12644	9606	GO:2000725	regulation of cardiac muscle cell differentiation	ARBA:ARBA00085921	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP6	P22004	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP6	P22004	9606	GO:0030509	BMP signaling pathway	ARBA:ARBA00086900	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/BMP6	P22004	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP6	P22004	9606	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP6	P22004	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMP6	P22004	9606	GO:2000026	regulation of multicellular organismal development	ARBA:ARBA00026275	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|ferroptosis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/BMPR1A	P36894	9606	GO:0030501	positive regulation of bone mineralization	ARBA:ARBA00086906	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/BMPR1A	P36894	9606	GO:0045669	positive regulation of osteoblast differentiation	ARBA:ARBA00084608	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/BMPR1A	P36894	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0001558	regulation of cell growth	ARBA:ARBA00090177	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0001944	vasculature development	ARBA:ARBA00091285	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0030324	lung development	ARBA:ARBA00087373	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0040017	positive regulation of locomotion	ARBA:ARBA00026460	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BMPR2	Q13873	9606	GO:2000026	regulation of multicellular organismal development	ARBA:ARBA00026275	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/BPTF	Q12830	9606	GO:0006338	chromatin remodeling	ARBA:ARBA00027994	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection	ACCEPT
human/BPTF	Q12830	9606	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection	KEEP_AS_NON_CORE
human/BPTF	Q12830	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection	ACCEPT
human/BRAF	P15056	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	ACCEPT
human/BRD4	O60885	9606	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|h	ACCEPT
human/BRIP1	Q9BX63	9606	GO:0006281	DNA repair	ARBA:ARBA00029008	ENTAILED	False	bacterial_nucleotide_excision_repair|muth_independent_mismatch_repair		bacterial_nucleotide_excision_repair:uvrb_activity|muth_independent_mismatch_repair:mutl_atpase	apoptotic_execution_phase|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/BRSK2	Q8IWQ3	9606	GO:0000086	G2/M transition of mitotic cell cycle	ARBA:ARBA00090227	ENTAILED	True	g2_m_transition		g2_m_transition:cak1|g2_m_transition:checkpoint_kinase|g2_m_transition:greatwall_kinase|g2_m_transition:polo_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_au	KEEP_AS_NON_CORE
human/BRSK2	Q8IWQ3	9606	GO:2000807	regulation of synaptic vesicle clustering	ARBA:ARBA00085644	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	UNDECIDED
human/BTK	Q06187	9606	GO:0042113	B cell activation	ARBA:ARBA00085935	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de	ACCEPT
human/BTK	Q06187	9606	GO:0050864	regulation of B cell activation	ARBA:ARBA00091725	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de	ACCEPT
human/BUB1B	O60566	9606	GO:0033045	regulation of sister chromatid segregation	ARBA:ARBA00029259	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|mitophag	ACCEPT
human/C1GALT1C1	Q96EU7	9606	GO:0006493	protein O-linked glycosylation	ARBA:ARBA00027289	NO_MODULE	False					ACCEPT
human/C2CD3	Q4AC94	9606	GO:0060271	cilium assembly	ARBA:ARBA00027837	NOT_ENTAILED	True	ciliary_transition_zone|intraflagellar_transport				ACCEPT
human/C2CD3	Q4AC94	9606	GO:0071539	protein localization to centrosome	ARBA:ARBA00092420	NO_MODULE	False					ACCEPT
human/C3	P01024	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/C3	P01024	9606	GO:2000427	positive regulation of apoptotic cell clearance	ARBA:ARBA00086842	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/CACNA1C	Q13936	9606	GO:0006936	muscle contraction	ARBA:ARBA00043367	NO_MODULE	False				bcl2_family_momp_control|phosphorylase_kinase_complex	ACCEPT
human/CACNA1C	Q13936	9606	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False				bcl2_family_momp_control|phosphorylase_kinase_complex	ACCEPT
human/CACNA1C	Q13936	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			bcl2_family_momp_control|phosphorylase_kinase_complex	KEEP_AS_NON_CORE
human/CACNA1C	Q13936	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			bcl2_family_momp_control|phosphorylase_kinase_complex	KEEP_AS_NON_CORE
human/CACNA1C	Q13936	9606	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	ARBA:ARBA00098387	NO_MODULE	False				bcl2_family_momp_control|phosphorylase_kinase_complex	ACCEPT
human/CACNA1D	Q01668	9606	GO:0006936	muscle contraction	ARBA:ARBA00043367	NO_MODULE	False				bcl2_family_momp_control|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/CACNA1D	Q01668	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	bcl2_family_momp_control|synaptic_vesicle_exocytosis		bcl2_family_momp_control:bax_pore_effector|synaptic_vesicle_exocytosis:cav2_calcium_channel		KEEP_AS_NON_CORE
human/CACNA1D	Q01668	9606	GO:0010959	regulation of metal ion transport	ARBA:ARBA00084460	NO_MODULE	False				bcl2_family_momp_control|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/CACNA1D	Q01668	9606	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			bcl2_family_momp_control|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/CACNA1D	Q01668	9606	GO:0051050	positive regulation of transport	ARBA:ARBA00034593	NO_MODULE	False				bcl2_family_momp_control|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/CACNA1F	O60840	9606	GO:0007601	visual perception	ARBA:ARBA00086021	NOT_ENTAILED	True	retinoid_visual_cycle			bcl2_family_momp_control	ACCEPT
human/CACNA1G	O43497	9606	GO:0070509	calcium ion import	ARBA:ARBA00085091	NO_MODULE	False				bcl2_family_momp_control	MODIFY
human/CAD	P27708	9606	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:aspartate_carbamoyltransferase_activity|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_glutaminase_component|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component|de_novo_pyrimidine_synthesis:dihydroorotase_activity	arginine_biosynthesis|cuproptosis|glutamate_glutamine_ammonia_hub|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|tetrahydrofolate_biosynthesis|urea_cycle|vitamin_b6_plp_metabolism	MODIFY
human/CAD	P27708	9606	GO:0072528	pyrimidine-containing compound biosynthetic process	ARBA:ARBA00026919	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:aspartate_carbamoyltransferase_activity|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_glutaminase_component|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component|de_novo_pyrimidine_synthesis:dihydroorotase_activity	arginine_biosynthesis|coenzyme_a_biosynthesis|cuproptosis|glutamate_glutamine_ammonia_hub|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|tetrahydrofolate_biosynthesis|urea_cycle|vitamin_b6_plp_metabolis	MODIFY
human/CAD	P27708	9606	GO:0090407	organophosphate biosynthetic process	ARBA:ARBA00029048	ENTAILED	False	de_novo_pyrimidine_synthesis|vitamin_b6_plp_metabolism		de_novo_pyrimidine_synthesis:aspartate_carbamoyltransferase_activity|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_glutaminase_component|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component|de_novo_pyrimidine_synthesis:dihydroorotase_activity|vitamin_b6_plp_metabolism:pdxt_glutaminase_activity	arginine_biosynthesis|cuproptosis|glutamate_glutamine_ammonia_hub|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|tetrahydrofolate_biosynthesis|urea_cycle	MODIFY
human/CALCA	P01258	9606	GO:0097646	calcitonin family receptor signaling pathway	ARBA:ARBA00050066	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/CALM1	P0DP23	9606	GO:0002027	regulation of heart rate	ARBA:ARBA00087882	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM1	P0DP23	9606	GO:0005513	detection of calcium ion	ARBA:ARBA00086881	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM1	P0DP23	9606	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	ARBA:ARBA00084948	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM1	P0DP23	9606	GO:0032465	regulation of cytokinesis	ARBA:ARBA00084247	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM1	P0DP23	9606	GO:0060291	long-term synaptic potentiation	ARBA:ARBA00091239	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM1	P0DP23	9606	GO:0097720	calcineurin-mediated signaling	ARBA:ARBA00090525	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM1	P0DP23	9606	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	ARBA:ARBA00091451	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM2	P0DP24	9606	GO:0002027	regulation of heart rate	ARBA:ARBA00087882	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM2	P0DP24	9606	GO:0005513	detection of calcium ion	ARBA:ARBA00086881	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM2	P0DP24	9606	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	ARBA:ARBA00084948	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM2	P0DP24	9606	GO:0032465	regulation of cytokinesis	ARBA:ARBA00084247	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM2	P0DP24	9606	GO:0060291	long-term synaptic potentiation	ARBA:ARBA00091239	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM2	P0DP24	9606	GO:0097720	calcineurin-mediated signaling	ARBA:ARBA00090525	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM2	P0DP24	9606	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	ARBA:ARBA00091451	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM3	P0DP25	9606	GO:0002027	regulation of heart rate	ARBA:ARBA00087882	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM3	P0DP25	9606	GO:0005513	detection of calcium ion	ARBA:ARBA00086881	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM3	P0DP25	9606	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	ARBA:ARBA00084948	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM3	P0DP25	9606	GO:0032465	regulation of cytokinesis	ARBA:ARBA00084247	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM3	P0DP25	9606	GO:0060291	long-term synaptic potentiation	ARBA:ARBA00091239	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CALM3	P0DP25	9606	GO:0097720	calcineurin-mediated signaling	ARBA:ARBA00090525	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CALM3	P0DP25	9606	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	ARBA:ARBA00091451	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CAMK2A	Q9UQM7	9606	GO:0060291	long-term synaptic potentiation	ARBA:ARBA00091239	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaph	ACCEPT
human/CARD11	Q9BXL7	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling		canonical_nlrp3_inflammasome:nlrp3_sensor|canonical_nlrp3_inflammasome:pycard_adaptor|cgas_sting_signaling:sting_signaling_adaptor|nlrp3_inflammasome:casp1_card_filament_autoprocessing|nlrp3_inflammasome:nlrp3_pyd_filament_adaptor|nlrp3_inflammasome:pycard_bipartite_adaptor|tlr2_heterodimer_lipopeptide_signaling:myd88_adaptor|tlr2_heterodimer_lipopeptide_signaling:tirap_adaptor|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif	ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyros	KEEP_AS_NON_CORE
human/CARD11	Q9BXL7	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|egfr_signaling|hedgehog_signaling|nlrp3_inflammasome|phosphotyrosine_adaptor_recruitment|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|wnt_signaling		canonical_nlrp3_inflammasome:nlrp3_sensor|canonical_nlrp3_inflammasome:pycard_adaptor|cgas_sting_signaling:sting_signaling_adaptor|egfr_signaling:grb2_drk_sem5_sos_adaptor|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_tail_recruitment|nlrp3_inflammasome:casp1_card_filament_autoprocessing|nlrp3_inflammasome:nlrp3_pyd_filament_adaptor|nlrp3_inflammasome:pycard_bipartite_adaptor|phosphotyrosine_adaptor_recruitment:adaptor_function|tlr2_heterodimer_lipopeptide_signaling:myd88_adaptor|tlr2_heterodimer_lipopeptide_signaling:tirap_adaptor|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif|wnt_signaling:dvl_recruitment|wnt_signaling:signalosome_assembly	ciliary_transition_zone|coenzyme_a_biosynthesis|ferroptosis|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|purine_nucleotide_in	KEEP_AS_NON_CORE
human/CARD11	Q9BXL7	9606	GO:0032743	positive regulation of interleukin-2 production	ARBA:ARBA00085753	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransf	KEEP_AS_NON_CORE
human/CARD11	Q9BXL7	9606	GO:0050870	positive regulation of T cell activation	ARBA:ARBA00029152	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransf	KEEP_AS_NON_CORE
human/CARMIL2	Q6F5E8	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_assembly_factors|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	UNDECIDED
human/CASP1	P29466	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	ENTAILED	False	apoptotic_execution_phase		apoptotic_execution_phase:casp3_executioner|apoptotic_execution_phase:casp6_executioner|apoptotic_execution_phase:casp7_executioner	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_synthesi	KEEP_AS_NON_CORE
human/CASP1	P29466	9606	GO:0006954	inflammatory response	ARBA:ARBA00045028	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:casp1_protease|canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:casp1_card_filament_autoprocessing|nlrp3_inflammasome:casp1_cytokine_precursor_cleavage|nlrp3_inflammasome:casp1_gsdmd_cleavage|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_synthesis	ACCEPT
human/CASP1	P29466	9606	GO:0032496	response to lipopolysaccharide	ARBA:ARBA00084357	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sph	KEEP_AS_NON_CORE
human/CASP1	P29466	9606	GO:0032731	positive regulation of interleukin-1 beta production	ARBA:ARBA00033916	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sph	ACCEPT
human/CASP1	P29466	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
human/CASP1	P29466	9606	GO:0065003	protein-containing complex assembly	ARBA:ARBA00029057	NOT_ENTAILED	False	chylomicron_assembly_secretion|complex_i_assembly_factors|complex_iv_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sph	ACCEPT
human/CASP10	Q92851	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism	ACCEPT
human/CASP3	P42574	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	ENTAILED	False	apoptotic_execution_phase		apoptotic_execution_phase:casp3_executioner|apoptotic_execution_phase:casp6_executioner|apoptotic_execution_phase:casp7_executioner|apoptotic_execution_phase:diablo_iap_antagonist	canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activatio	ACCEPT
human/CASP3	P42574	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_cat	ACCEPT
human/CASP3	P42574	9606	GO:0072734	cellular response to staurosporine	ARBA:ARBA00092857	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_cat	KEEP_AS_NON_CORE
human/CASP4	P49662	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|primary_cilium_life_cycle	ACCEPT
human/CASP4	P49662	9606	GO:0065003	protein-containing complex assembly	ARBA:ARBA00029057	NOT_ENTAILED	False	chylomicron_assembly_secretion|complex_i_assembly_factors|complex_iv_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii			apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|primary_cilium_life_cycle|protease_activation_cascade	MODIFY
human/CASP4	P49662	9606	GO:0097193	intrinsic apoptotic signaling pathway	ARBA:ARBA00028303	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|primary_cilium_life_cycle|protease_activation_cascade	KEEP_AS_NON_CORE
human/CASP6	P55212	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism	MODIFY
human/CASP6	P55212	9606	GO:0070269	pyroptotic inflammatory response	ARBA:ARBA00091826	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:casp1_cytokine_precursor_cleavage|nlrp3_inflammasome:casp1_gsdmd_cleavage|nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|canonical_nlrp3_inflammasome|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CASP6	P55212	9606	GO:0072734	cellular response to staurosporine	ARBA:ARBA00092857	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	REMOVE
human/CASP6	P55212	9606	GO:0097193	intrinsic apoptotic signaling pathway	ARBA:ARBA00028303	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CASP7	P55210	9606	GO:0009617	response to bacterium	ARBA:ARBA00026494	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
human/CASP7	P55210	9606	GO:0097194	execution phase of apoptosis	ARBA:ARBA00090101	ENTAILED	True	apoptotic_execution_phase		apoptotic_execution_phase:acin1_chromatin_condensation|apoptotic_execution_phase:casp3_executioner|apoptotic_execution_phase:casp6_executioner|apoptotic_execution_phase:casp7_executioner	canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CASP8	Q14790	9606	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:casp1_protease|canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:casp1_cytokine_precursor_cleavage|nlrp3_inflammasome:casp1_gsdmd_cleavage|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|phenylacetate_catabolism|protease_activation_cascade|sphingol	KEEP_AS_NON_CORE
human/CASP8	Q14790	9606	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	ARBA:ARBA00084513	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	ACCEPT
human/CASP8	Q14790	9606	GO:0009967	positive regulation of signal transduction	ARBA:ARBA00027202	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	KEEP_AS_NON_CORE
human/CASP8	Q14790	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	KEEP_AS_NON_CORE
human/CASP8	Q14790	9606	GO:0043009	chordate embryonic development	ARBA:ARBA00027425	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	KEEP_AS_NON_CORE
human/CASP8	Q14790	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	KEEP_AS_NON_CORE
human/CASP8	Q14790	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	ACCEPT
human/CASP9	P55211	9606	GO:0006974	DNA damage response	ARBA:ARBA00026271	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_sy	MARK_AS_OVER_ANNOTATED
human/CASP9	P55211	9606	GO:0009411	response to UV	ARBA:ARBA00028103	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_sy	MARK_AS_OVER_ANNOTATED
human/CASP9	P55211	9606	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
human/CASQ2	O14958	9606	GO:0051258	protein polymerization	ARBA:ARBA00028914	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
human/CASQ2	O14958	9606	GO:0051279	regulation of release of sequestered calcium ion into cytosol	ARBA:ARBA00089315	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
human/CASR	P41180	9606	GO:1902533	positive regulation of intracellular signal transduction	ARBA:ARBA00027124	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling	ACCEPT
human/CBFB	Q13951	9606	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
human/CBL	P22681	9606	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	UNDECIDED
human/CBL	P22681	9606	GO:0050860	negative regulation of T cell receptor signaling pathway	ARBA:ARBA00091732	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	ACCEPT
human/CBL	P22681	9606	GO:0050868	negative regulation of T cell activation	ARBA:ARBA00091719	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	KEEP_AS_NON_CORE
human/CBL	P22681	9606	GO:0070534	protein K63-linked ubiquitination	ARBA:ARBA00085191	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	ACCEPT
human/CBS	P35520	9606	GO:0006534	cysteine metabolic process	ARBA:ARBA00026351	NO_MODULE	False				complex_i_assembly_factors|fungal_sulfur_amino_acid_transsulfuration|heat_shock_response|homocysteine_metabolism|methionine_cycle|methylcitrate_cycle|mitochondrial_complex_ii|mitochondrial_upr|nitrogen_cycle|nlrp3_inflammasome	ACCEPT
human/CBS	P35520	9606	GO:0044272	sulfur compound biosynthetic process	ARBA:ARBA00028512	NOT_ENTAILED	False	bacterial_cysteine_biosynthesis_via_o_acetylserine|biotin_biosynthesis|coenzyme_a_biosynthesis|fatty_acid_de_novo_synthesis|glutathione_biosynthesis			complex_i_assembly_factors|fungal_sulfur_amino_acid_transsulfuration|heat_shock_response|homocysteine_metabolism|methionine_cycle|methylcitrate_cycle|mitochondrial_complex_ii|mitochondrial_upr|nitrogen_cycle|nlrp3_inflammasome	ACCEPT
human/CBS	P35520	9606	GO:0050667	homocysteine metabolic process	ARBA:ARBA00089512	ENTAILED	True	fungal_sulfur_amino_acid_transsulfuration|homocysteine_metabolism|methionine_cycle		fungal_sulfur_amino_acid_transsulfuration:cystathionine_beta_synthase_activity|homocysteine_metabolism:cbs_activity|methionine_cycle:cbs_activity	complex_i_assembly_factors|heat_shock_response|methylcitrate_cycle|mitochondrial_complex_ii|mitochondrial_upr|nitrogen_cycle|nlrp3_inflammasome	ACCEPT
human/CCM2	Q9BSQ5	9606	GO:0001570	vasculogenesis	ARBA:ARBA00090144	NO_MODULE	False					KEEP_AS_NON_CORE
human/CCM2	Q9BSQ5	9606	GO:0003158	endothelium development	ARBA:ARBA00088444	NO_MODULE	False					KEEP_AS_NON_CORE
human/CCN6	O95389	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling	KEEP_AS_NON_CORE
human/CCND1	P24385	9606	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	ENTAILED	True	g1_s_transition		g1_s_transition:g1_cyclin|g1_s_transition:g1s_cyclin|g1_s_transition:rb_corepressor|g1_s_transition:whi5_corepressor	canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|peptid	ACCEPT
human/CCND1	P24385	9606	GO:1901992	positive regulation of mitotic cell cycle phase transition	ARBA:ARBA00029089	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|g2_m_transition|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_	ACCEPT
human/CCND1	P24385	9606	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ARBA:ARBA00033889	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|g2_m_transition|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_	ACCEPT
human/CCND2	P30279	9606	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	ENTAILED	True	g1_s_transition		g1_s_transition:g1_cyclin|g1_s_transition:g1s_cyclin	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|g2_m_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CCND2	P30279	9606	GO:1901992	positive regulation of mitotic cell cycle phase transition	ARBA:ARBA00029089	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|g1_s_transition|g2_m_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CCND2	P30279	9606	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ARBA:ARBA00033889	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|g1_s_transition|g2_m_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/CCNO	P22674	9606	GO:0060271	cilium assembly	ARBA:ARBA00027837	NOT_ENTAILED	True	ciliary_transition_zone|intraflagellar_transport			g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	ACCEPT
human/CCNO	P22674	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CD28	P10747	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|notch_signaling	ACCEPT
human/CD28	P10747	9606	GO:0050870	positive regulation of T cell activation	ARBA:ARBA00029152	NO_MODULE	False				fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling	ACCEPT
human/CD320	Q9NPF0	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	cobalamin_absorption_transport		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cblif_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|cobalamin_absorption_transport:tcn1_activity|cobalamin_absorption_transport:tcn2_activity	gpcr_plc_calcium_pkc_signaling|wnt_signaling	MODIFY
human/CD3D	P04234	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	heat_shock_response|notch_signaling	KEEP_AS_NON_CORE
human/CD3E	P07766	9606	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	KEEP_AS_NON_CORE
human/CD3E	P07766	9606	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	MARK_AS_OVER_ANNOTATED
human/CD3E	P07766	9606	GO:0042102	positive regulation of T cell proliferation	ARBA:ARBA00085815	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	KEEP_AS_NON_CORE
human/CD3E	P07766	9606	GO:0050852	T cell receptor signaling pathway	ARBA:ARBA00091705	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	ACCEPT
human/CD4	P01730	9606	GO:0002684	positive regulation of immune system process	ARBA:ARBA00027011	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|notch_signaling|primary_cilium_life_cycle|synaptic_vesi	KEEP_AS_NON_CORE
human/CD4	P01730	9606	GO:0050863	regulation of T cell activation	ARBA:ARBA00029128	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|notch_signaling|primary_cilium_life_	ACCEPT
human/CD4	P01730	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|notch_signaling|primary_cilium_life_	KEEP_AS_NON_CORE
human/CD40	P25942	9606	GO:0006952	defense response	ARBA:ARBA00026315	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome				KEEP_AS_NON_CORE
human/CD40	P25942	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation				KEEP_AS_NON_CORE
human/CD40	P25942	9606	GO:0051094	positive regulation of developmental process	ARBA:ARBA00027577	NO_MODULE	False					KEEP_AS_NON_CORE
human/CD40	P25942	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False					KEEP_AS_NON_CORE
human/CD40LG	P29965	9606	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|neurexin_transsynaptic_adhesion|notch_signaling|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/CD40LG	P29965	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling		canonical_nlrp3_inflammasome:nek7_licensing|egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|nlrp3_inflammasome:nek7_nlrp3_licensing|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand|tgfb_smad_signaling:tgfb_ligand	complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|metazoan_autophagosome_biogenesis|mitochondrial_upr|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/CD40LG	P29965	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CD40LG	P29965	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling		canonical_nlrp3_inflammasome:nek7_licensing|egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|nlrp3_inflammasome:nek7_nlrp3_licensing|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand|tgfb_smad_signaling:tgfb_ligand	complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|metazoan_autophagosome_biogenesis|mitochondrial_upr|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	MODIFY
human/CD46	P15529	9606	GO:0050776	regulation of immune response	ARBA:ARBA00028647	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			er_unfolded_protein_response|hedgehog_signaling	KEEP_AS_NON_CORE
human/CD47	Q08722	9606	GO:0002684	positive regulation of immune system process	ARBA:ARBA00027011	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			complex_i_assembly_factors|neurexin_transsynaptic_adhesion	KEEP_AS_NON_CORE
human/CD47	Q08722	9606	GO:0098609	cell-cell adhesion	ARBA:ARBA00026305	ENTAILED	False	neurexin_transsynaptic_adhesion		neurexin_transsynaptic_adhesion:neurexin_adhesion_activity	complex_i_assembly_factors	ACCEPT
human/CD48	P09326	9606	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/CD70	P32970	9606	GO:0042110	T cell activation	ARBA:ARBA00085932	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/CD70	P32970	9606	GO:0046651	lymphocyte proliferation	ARBA:ARBA00091995	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	MODIFY
human/CD79B	P40259	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	heat_shock_response|notch_signaling	MODIFY
human/CD79B	P40259	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	nlrp3_inflammasome|notch_signaling		nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:notch_receptor	heat_shock_response	MODIFY
human/CD86	P42081	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	canonical_nlrp3_inflammasome|egfr_signaling|fgfr_signaling|nlrp3_inflammasome|notch_signaling		canonical_nlrp3_inflammasome:nek7_licensing|egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|fgfr_signaling:klotho_coreceptor|nlrp3_inflammasome:nek7_nlrp3_licensing|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand	neurexin_transsynaptic_adhesion	KEEP_AS_NON_CORE
human/CD86	P42081	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	MODIFY
human/CD86	P42081	9606	GO:0009967	positive regulation of signal transduction	ARBA:ARBA00027202	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/CD86	P42081	9606	GO:0046649	lymphocyte activation	ARBA:ARBA00091981	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	MODIFY
human/CD86	P42081	9606	GO:0050778	positive regulation of immune response	ARBA:ARBA00028646	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	egfr_signaling|fgfr_signaling|neurexin_transsynaptic_adhesion|notch_signaling	ACCEPT
human/CD8A	P01732	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	erbb2_signaling|fgfr_signaling		erbb2_signaling:nrg1_nrg1_ligand|fgfr_signaling:klotho_coreceptor	complex_i_assembly_factors	ACCEPT
human/CD8A	P01732	9606	GO:0042110	T cell activation	ARBA:ARBA00085932	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|fgfr_signaling	ACCEPT
human/CDA	P32320	9606	GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	ARBA:ARBA00090981	NOT_ENTAILED	False	de_novo_pyrimidine_synthesis			heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism	MARK_AS_OVER_ANNOTATED
human/CDA	P32320	9606	GO:0009218	pyrimidine ribonucleotide metabolic process	ARBA:ARBA00090558	NOT_ENTAILED	False	de_novo_pyrimidine_synthesis			heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism	MARK_AS_OVER_ANNOTATED
human/CDC25C	P30307	9606	GO:0000086	G2/M transition of mitotic cell cycle	ARBA:ARBA00090227	ENTAILED	True	g2_m_transition		g2_m_transition:cdc25_phosphatase	cerebellum_development|gpi_anchor_remodeling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|necroptosis|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	ACCEPT
human/CDC25C	P30307	9606	GO:0008283	cell population proliferation	ARBA:ARBA00035743	NOT_ENTAILED	False	nucleokinesis			cerebellum_development|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|necroptosis|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	KEEP_AS_NON_CORE
human/CDC42	P60953	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			alginate_o_acetylation|cell_cycle_progression|chylomicron_assembly_secretion|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|nlrp3_inflamm	KEEP_AS_NON_CORE
human/CDC42	P60953	9606	GO:0051130	positive regulation of cellular component organization	ARBA:ARBA00026675	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|chylomicron_assembly_secretion|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|nlrp3_inflamm	KEEP_AS_NON_CORE
human/CDC42	P60953	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			alginate_o_acetylation|cell_cycle_progression|chylomicron_assembly_secretion|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|nlrp3_inflamm	KEEP_AS_NON_CORE
human/CDH1	P12830	9606	GO:0034329	cell junction assembly	ARBA:ARBA00029029	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CDHR1	Q96JP9	9606	GO:0045494	photoreceptor cell maintenance	ARBA:ARBA00085416	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	ACCEPT
human/CDK13	Q14004	9606	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	ARBA:ARBA00033872	NO_MODULE	False				apoptotic_execution_phase|cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kin	ACCEPT
human/CDK4	P11802	9606	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	ENTAILED	True	g1_s_transition		g1_s_transition:g1_cdk|g1_s_transition:g1_cyclin|g1_s_transition:g1s_cdk|g1_s_transition:g1s_cyclin	cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_	ACCEPT
human/CDK4	P11802	9606	GO:0048146	positive regulation of fibroblast proliferation	ARBA:ARBA00089974	NO_MODULE	False				cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|met	KEEP_AS_NON_CORE
human/CDK5	Q00535	9606	GO:0007409	axonogenesis	ARBA:ARBA00026520	NO_MODULE	False				apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|fgfr_signaling|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_s	ACCEPT
human/CDK5	Q00535	9606	GO:0051649	establishment of localization in cell	ARBA:ARBA00028679	ENTAILED	False	intraflagellar_transport|nucleokinesis		intraflagellar_transport:dyf5_kinase|nucleokinesis:cdk5_p35_kinase	apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|fgfr_signaling|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_s	KEEP_AS_NON_CORE
human/CDK5	Q00535	9606	GO:0051726	regulation of cell cycle	ARBA:ARBA00029144	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|fgfr_signaling|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_s	ACCEPT
human/CDKN1B	P46527	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	apoptotic_execution_phase|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|phagosome_maturation|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CDKN1B	P46527	9606	GO:0008285	negative regulation of cell population proliferation	ARBA:ARBA00027539	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|phagosome_maturation|sphingoli	ACCEPT
human/CDKN1B	P46527	9606	GO:0045926	negative regulation of growth	ARBA:ARBA00028151	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|phagosome_maturation|sphingoli	KEEP_AS_NON_CORE
human/CDKN1B	P46527	9606	GO:1901990	regulation of mitotic cell cycle phase transition	ARBA:ARBA00029095	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|phagosome_maturation|sphingoli	ACCEPT
human/CDKN1C	P49918	9606	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	MODIFY
human/CDKN2A	P42771	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				apoptotic_execution_phase|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
human/CDKN2A	P42771	9606	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ARBA:ARBA00033889	NO_MODULE	False				apoptotic_execution_phase|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
human/CDO1	Q16878	9606	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	ENTAILED	False	taurine_biosynthesis_and_transport		taurine_biosynthesis_and_transport:cdo1_activity	complex_i_assembly_factors|urease_biogenesis_urea_hydrolysis	ACCEPT
human/CDT1	Q9H211	9606	GO:0090329	regulation of DNA-templated DNA replication	ARBA:ARBA00026722	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection	ACCEPT
human/CEP120	Q8N960	9606	GO:0010824	regulation of centrosome duplication	ARBA:ARBA00084913	NO_MODULE	False					MODIFY
human/CEP120	Q8N960	9606	GO:0032880	regulation of protein localization	ARBA:ARBA00026609	NO_MODULE	False					MODIFY
human/CEP120	Q8N960	9606	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False					MODIFY
human/CEP120	Q8N960	9606	GO:1902117	positive regulation of organelle assembly	ARBA:ARBA00088865	NO_MODULE	False					MODIFY
human/CFAP43	Q8NDM7	9606	GO:0003341	cilium movement	ARBA:ARBA00034388	NO_MODULE	False					ACCEPT
human/CFH	P08603	9606	GO:0006954	inflammatory response	ARBA:ARBA00045028	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	heat_shock_response	MODIFY
human/CFH	P08603	9606	GO:0006957	complement activation, alternative pathway	ARBA:ARBA00086627	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	MODIFY
human/CFH	P08603	9606	GO:0022008	neurogenesis	ARBA:ARBA00028404	NOT_ENTAILED	False	nucleokinesis			heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CFH	P08603	9606	GO:0030449	regulation of complement activation	ARBA:ARBA00027989	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	MODIFY
human/CFH	P08603	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CFL2	Q9Y281	9606	GO:0008154	actin polymerization or depolymerization	ARBA:ARBA00028283	NO_MODULE	False				complex_i_assembly_factors|phagocytic_engulfment	ACCEPT
human/CFLAR	O15519	9606	GO:0060544	regulation of necroptotic process	ARBA:ARBA00090640	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease	ACCEPT
human/CFLAR	O15519	9606	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ARBA:ARBA00087856	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease	MODIFY
human/CFTR	P13569	9606	GO:0015701	bicarbonate transport	ARBA:ARBA00034575	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bcl2_family_momp_control|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|methylcitrate_cycle|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|pri	ACCEPT
human/CFTR	P13569	9606	GO:0098660	obsolete inorganic ion transmembrane transport	ARBA:ARBA00026667	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bcl2_family_momp_control|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|methylcitrate_cycle|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|pri	MODIFY
human/CHCHD4	Q8N4Q1	9606	GO:0033108	mitochondrial respiratory chain complex assembly	ARBA:ARBA00092694	ENTAILED	False	complex_i_assembly_factors|complex_iv_assembly_factors		complex_i_assembly_factors:foxred1_activity|complex_i_assembly_factors:ndufaf5_activity|complex_iv_assembly_factors:coa6_activity|complex_iv_assembly_factors:coa7_activity	aps_dependent_assimilatory_sulfate_reduction|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	KEEP_AS_NON_CORE
human/CHD2	O14647	9606	GO:0006338	chromatin remodeling	ARBA:ARBA00027994	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	ACCEPT
human/CHD7	Q9P2D1	9606	GO:0001701	in utero embryonic development	ARBA:ARBA00089616	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0003007	heart morphogenesis	ARBA:ARBA00086699	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0021545	cranial nerve development	ARBA:ARBA00085097	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0042472	inner ear morphogenesis	ARBA:ARBA00087234	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0043010	camera-type eye development	ARBA:ARBA00084629	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0043584	nose development	ARBA:ARBA00085692	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0048806	genitalia development	ARBA:ARBA00090613	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	UNDECIDED
human/CHD7	Q9P2D1	9606	GO:0060021	roof of mouth development	ARBA:ARBA00089452	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0060173	limb development	ARBA:ARBA00091631	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHD7	Q9P2D1	9606	GO:0060322	head development	ARBA:ARBA00028411	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|ferroptosis|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	KEEP_AS_NON_CORE
human/CHEK1	O14757	9606	GO:0042770	signal transduction in response to DNA damage	ARBA:ARBA00088532	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/CHEK1	O14757	9606	GO:1901988	negative regulation of cell cycle phase transition	ARBA:ARBA00029277	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/CHEK2	O96017	9606	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	ARBA:ARBA00027191	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/CHEK2	O96017	9606	GO:0030330	DNA damage response, signal transduction by p53 class mediator	ARBA:ARBA00093717	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
human/CHMP1A	Q9HD42	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
human/CHMP1A	Q9HD42	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
human/CHMP1A	Q9HD42	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1A	Q9HD42	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
human/CHMP1A	Q9HD42	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP1B	Q7LBR1	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP1B	Q7LBR1	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP1B	Q7LBR1	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP1B	Q7LBR1	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP1B	Q7LBR1	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP2A	O43633	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/CHMP2A	O43633	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2A	O43633	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/CHMP2A	O43633	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP2B	Q9UQN3	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False					ACCEPT
human/CHMP2B	Q9UQN3	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False					ACCEPT
human/CHMP2B	Q9UQN3	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False					ACCEPT
human/CHMP2B	Q9UQN3	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False					ACCEPT
human/CHMP2B	Q9UQN3	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP2B	Q9UQN3	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP3	Q9Y3E7	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP3	Q9Y3E7	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				apoptotic_execution_phase|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/CHMP4A	Q9BY43	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4A	Q9BY43	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4A	Q9BY43	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4A	Q9BY43	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4A	Q9BY43	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4A	Q9BY43	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4B	Q9H444	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4B	Q9H444	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4B	Q9H444	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4B	Q9H444	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4B	Q9H444	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4B	Q9H444	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4C	Q96CF2	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/CHMP4C	Q96CF2	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/CHMP4C	Q96CF2	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/CHMP4C	Q96CF2	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP4C	Q96CF2	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
human/CHMP5	Q9NZZ3	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False					ACCEPT
human/CHMP5	Q9NZZ3	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
human/CHMP5	Q9NZZ3	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False					ACCEPT
human/CHMP5	Q9NZZ3	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP5	Q9NZZ3	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False					ACCEPT
human/CHMP6	Q96FZ7	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/CHMP6	Q96FZ7	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/CHMP6	Q96FZ7	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False				complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/CHMP6	Q96FZ7	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/CHMP6	Q96FZ7	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
human/CHMP6	Q96FZ7	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/CHMP7	Q8WUX9	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:0031468	nuclear membrane reassembly	ARBA:ARBA00033562	NO_MODULE	False					ACCEPT
human/CHMP7	Q8WUX9	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
human/CHMP7	Q8WUX9	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:0046761	viral budding from plasma membrane	ARBA:ARBA00033532	NO_MODULE	False					MARK_AS_OVER_ANNOTATED
human/CHMP7	Q8WUX9	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:0071985	multivesicular body sorting pathway	ARBA:ARBA00033501	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHMP7	Q8WUX9	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False					MODIFY
human/CHMP7	Q8WUX9	9606	GO:1902774	late endosome to lysosome transport	ARBA:ARBA00033593	NO_MODULE	False					KEEP_AS_NON_CORE
human/CHRM1	P11229	9606	GO:0095500	acetylcholine receptor signaling pathway	ARBA:ARBA00027667	NO_MODULE	False				cerebellum_development|fgfr_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|hedgehog_signaling|myo_inositol_and_inositol_phosphate_biosynthesis|notch_signaling|phenylacetate_catabolism	MODIFY
human/CHRNA1	P02708	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	bcl2_family_momp_control|notch_signaling		bcl2_family_momp_control:bax_pore_effector|notch_signaling:notch_receptor		MODIFY
human/CHRNA1	P02708	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	bcl2_family_momp_control|notch_signaling		bcl2_family_momp_control:bax_pore_effector|notch_signaling:notch_receptor		MODIFY
human/CHRNA1	P02708	9606	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False				bcl2_family_momp_control|notch_signaling	MODIFY
human/CHRNA4	P43681	9606	GO:0095500	acetylcholine receptor signaling pathway	ARBA:ARBA00027667	NO_MODULE	False				bcl2_family_momp_control|notch_signaling	ACCEPT
human/CHRNB1	P11230	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	bcl2_family_momp_control|notch_signaling		bcl2_family_momp_control:bax_pore_effector|notch_signaling:notch_receptor		MODIFY
human/CHRNB1	P11230	9606	GO:0007268	chemical synaptic transmission	ARBA:ARBA00028185	NOT_ENTAILED	False	synaptic_vesicle_exocytosis			bcl2_family_momp_control|notch_signaling	ACCEPT
human/CHRNB1	P11230	9606	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			bcl2_family_momp_control|notch_signaling	KEEP_AS_NON_CORE
human/CHRNB2	P17787	9606	GO:0035094	response to nicotine	ARBA:ARBA00089505	NO_MODULE	False				bcl2_family_momp_control|notch_signaling	KEEP_AS_NON_CORE
human/CHRNB2	P17787	9606	GO:0095500	acetylcholine receptor signaling pathway	ARBA:ARBA00027667	NO_MODULE	False				bcl2_family_momp_control|notch_signaling	ACCEPT
human/CHRNG	P07510	9606	GO:0006936	muscle contraction	ARBA:ARBA00043367	NO_MODULE	False				bcl2_family_momp_control|notch_signaling	MODIFY
human/CHRNG	P07510	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	bcl2_family_momp_control|notch_signaling		bcl2_family_momp_control:bax_pore_effector|notch_signaling:notch_receptor		MODIFY
human/CHRNG	P07510	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	bcl2_family_momp_control|notch_signaling		bcl2_family_momp_control:bax_pore_effector|notch_signaling:notch_receptor		MODIFY
human/CHST3	Q7LGC8	9606	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	NOT_ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|bacterial_cysteine_biosynthesis_via_o_acetylserine|bacterial_methionine_cycle|biotin_biosynthesis|biotin_cycle				MODIFY
human/CHST3	Q7LGC8	9606	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	ARBA:ARBA00034383	NO_MODULE	False					ACCEPT
human/CHST6	Q9GZX3	9606	GO:0006044	obsolete N-acetylglucosamine metabolic process	ARBA:ARBA00084676	NO_MODULE	False					MODIFY
human/CHST6	Q9GZX3	9606	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	NOT_ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|bacterial_cysteine_biosynthesis_via_o_acetylserine|bacterial_methionine_cycle|biotin_biosynthesis|biotin_cycle				MODIFY
human/CHST6	Q9GZX3	9606	GO:0009101	glycoprotein biosynthetic process	ARBA:ARBA00027560	NOT_ENTAILED	False	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|n_glycan_llo_assembly_cytoplasmic|n_glycan_llo_assembly_lumenal|oligosaccharyltransferase_complex				MODIFY
human/CHSY1	Q86X52	9606	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	ARBA:ARBA00034383	NO_MODULE	False					ACCEPT
human/CIITA	P33076	9606	GO:0034341	response to type II interferon	ARBA:ARBA00033603	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle	ACCEPT
human/CIITA	P33076	9606	GO:0045892	negative regulation of DNA-templated transcription	ARBA:ARBA00029084	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle	KEEP_AS_NON_CORE
human/CIITA	P33076	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle	ACCEPT
human/CIRBP	Q14011	9606	GO:0009409	response to cold	ARBA:ARBA00028088	NO_MODULE	False				apoptotic_execution_phase|early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	ACCEPT
human/CLN3	Q13286	9606	GO:0006865	amino acid transport	ARBA:ARBA00027044	NOT_ENTAILED	False	mitochondrial_dicarboxylate_tricarboxylate_carriers|mitochondrial_nucleotide_glycine_carriers			chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/CLN3	Q13286	9606	GO:0006897	endocytosis	ARBA:ARBA00027119	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis			chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/CLN3	Q13286	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|snare_fusion_cycle|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis			chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/CLN3	Q13286	9606	GO:0030003	intracellular monoatomic cation homeostasis	ARBA:ARBA00028070	NO_MODULE	False				chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/CLN3	Q13286	9606	GO:0030162	regulation of proteolysis	ARBA:ARBA00027404	NO_MODULE	False				chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/CLN3	Q13286	9606	GO:0061024	membrane organization	ARBA:ARBA00028824	NOT_ENTAILED	False	phagocytic_engulfment|snare_fusion_cycle|vesicle_coat_budding			chylomicron_assembly_secretion|cobalamin_intracellular_processing|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/CLRN1	P58418	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False					ACCEPT
human/CLTC	Q00610	9606	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	ENTAILED	False	ldl_receptor_mediated_endocytosis		ldl_receptor_mediated_endocytosis:apob_ldlr_binding|ldl_receptor_mediated_endocytosis:pcsk9_ldlr_binding	apoptotic_execution_phase|cgas_sting_signaling|complex_i_accessory_subunits|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_buddi	ACCEPT
human/CLTC	Q00610	9606	GO:0042147	retrograde transport, endosome to Golgi	ARBA:ARBA00085977	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|complex_i_accessory_subunits|erbb2_signaling|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesi	ACCEPT
human/CLYBL	Q8N0X4	9606	GO:0106064	regulation of cobalamin catabolic process	ARBA:ARBA00091618	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
human/CNGB3	Q9NQW8	9606	GO:0007601	visual perception	ARBA:ARBA00086021	NOT_ENTAILED	True	retinoid_visual_cycle			bcl2_family_momp_control	ACCEPT
human/CNTNAP2	Q9UHC6	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	NOT_ENTAILED	False	cerebellum_development|nucleokinesis				KEEP_AS_NON_CORE
human/COL11A2	P13942	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|necrop	KEEP_AS_NON_CORE
human/COL11A2	P13942	9606	GO:0030199	collagen fibril organization	ARBA:ARBA00085945	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|necrop	ACCEPT
human/COL11A2	P13942	9606	GO:0051216	cartilage development	ARBA:ARBA00089273	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|necrop	KEEP_AS_NON_CORE
human/COL18A1	P39060	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL18A1	P39060	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL18A1	P39060	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL1A1	P02452	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL1A2	P08123	9606	GO:0030199	collagen fibril organization	ARBA:ARBA00085945	NO_MODULE	False				ciliary_transition_zone|complex_i_accessory_subunits|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_comple	ACCEPT
human/COL1A2	P08123	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	ciliary_transition_zone|complex_i_accessory_subunits|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_comple	KEEP_AS_NON_CORE
human/COL2A1	P02458	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|erbb2_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL3A1	P02461	9606	GO:0030199	collagen fibril organization	ARBA:ARBA00085945	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
human/COL3A1	P02461	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL5A2	P05997	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL6A1	P12109	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			complex_i_accessory_subunits|complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL6A1	P12109	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			complex_i_accessory_subunits|complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL6A1	P12109	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			complex_i_accessory_subunits|complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	UNDECIDED
human/COL6A1	P12109	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|complex_i_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/COL9A1	P20849	9606	GO:0009887	animal organ morphogenesis	ARBA:ARBA00028067	NO_MODULE	False				complex_i_accessory_subunits|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	UNDECIDED
human/CORO1A	P31146	9606	GO:0051129	negative regulation of cellular component organization	ARBA:ARBA00026626	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phagocytic_engulfment	MODIFY
human/COX10	Q12887	9606	GO:0006784	heme A biosynthetic process	ARBA:ARBA00087087	NO_MODULE	False				isoprenoid_diphosphate_biosynthesis|methionine_biosynthesis	ACCEPT
human/COX10	Q12887	9606	GO:0017004	cytochrome complex assembly	ARBA:ARBA00086146	NOT_ENTAILED	False	complex_iv_assembly_factors|mitochondrial_complex_iii|mitochondrial_complex_iv			isoprenoid_diphosphate_biosynthesis|methionine_biosynthesis	MODIFY
human/COX18	Q8N8Q8	9606	GO:0051205	protein insertion into membrane	ARBA:ARBA00028605	NO_MODULE	False				cobalamin_intracellular_processing|complex_iv_assembly_factors|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MODIFY
human/CPAP	Q9HC77	9606	GO:0007099	centriole replication	ARBA:ARBA00092134	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|retinal_determination_network|wnt_signaling	ACCEPT
human/CPAP	Q9HC77	9606	GO:1902117	positive regulation of organelle assembly	ARBA:ARBA00088865	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|retinal_determination_network|wnt_signaling	MODIFY
human/CPS1	P31327	9606	GO:0090407	organophosphate biosynthetic process	ARBA:ARBA00029048	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component	arginine_biosynthesis|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|phenylacetate_catabolism|primary_cilium_life_cycle|protease_activation_cascade|synaptic_vesicle_endocytosis|urea_cycle	MODIFY
human/CPT2	P23786	9606	GO:0015909	long-chain fatty acid transport	ARBA:ARBA00088749	ENTAILED	False	carnitine_shuttle		carnitine_shuttle:cpt1a_activity|carnitine_shuttle:cpt2_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	MODIFY
human/CR1	P17927	9606	GO:0006957	complement activation, alternative pathway	ARBA:ARBA00086627	NO_MODULE	False				notch_signaling	ACCEPT
human/CR1	P17927	9606	GO:0030449	regulation of complement activation	ARBA:ARBA00027989	NO_MODULE	False				notch_signaling	ACCEPT
human/CR1	P17927	9606	GO:1903659	regulation of complement-dependent cytotoxicity	ARBA:ARBA00089218	NO_MODULE	False				notch_signaling	ACCEPT
human/CR2	P20023	9606	GO:0006957	complement activation, alternative pathway	ARBA:ARBA00086627	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/CR2	P20023	9606	GO:0046718	symbiont entry into host cell	ARBA:ARBA00043454	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/CRADD	P78560	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/CRB1	P82279	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	gpcr_plc_calcium_pkc_signaling		gpcr_plc_calcium_pkc_signaling:calmodulin_sensor		ACCEPT
human/CRB1	P82279	9606	GO:0007163	establishment or maintenance of cell polarity	ARBA:ARBA00029058	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling	MODIFY
human/CRB1	P82279	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	gpcr_plc_calcium_pkc_signaling		gpcr_plc_calcium_pkc_signaling:calmodulin_sensor		UNDECIDED
human/CREBBP	Q92793	9606	GO:0002223	stimulatory C-type lectin receptor signaling pathway	ARBA:ARBA00087826	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:0007249	canonical NF-kappaB signal transduction	ARBA:ARBA00085080	NOT_ENTAILED	True	nfkb_canonical_signaling			alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ARBA:ARBA00086893	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:0031669	cellular response to nutrient levels	ARBA:ARBA00034580	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
human/CREBBP	Q92793	9606	GO:1900034	regulation of cellular response to heat	ARBA:ARBA00092510	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:1900182	positive regulation of protein localization to nucleus	ARBA:ARBA00092943	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CREBBP	Q92793	9606	GO:2000819	regulation of nucleotide-excision repair	ARBA:ARBA00033899	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CRISPLD1	Q9H336	9606	GO:0060325	face morphogenesis	ARBA:ARBA00091405	NO_MODULE	False				ciliary_transition_zone|mitophagy|phagosome_maturation	MARK_AS_OVER_ANNOTATED
human/CRLS1	Q9UJA2	9606	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:agpat2_activity|triacylglycerol_biosynthesis:loa1_lpaat_activity|triacylglycerol_biosynthesis:mboat_lpaat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
human/CRPPA	A4D126	9606	GO:0009101	glycoprotein biosynthetic process	ARBA:ARBA00027560	NOT_ENTAILED	False	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|n_glycan_llo_assembly_cytoplasmic|n_glycan_llo_assembly_lumenal|oligosaccharyltransferase_complex			heat_shock_response|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	MODIFY
human/CRX	O43186	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/CRYAB	P02511	9606	GO:0009892	negative regulation of metabolic process	ARBA:ARBA00028100	NOT_ENTAILED	False	pirna_mediated_germline_silencing			ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|nucleokinesis|primary_cilium_life_cycle|synaptic_vesicle_cycle|synaptic_vesic	MARK_AS_OVER_ANNOTATED
human/CSF1R	P07333	9606	GO:0002573	myeloid leukocyte differentiation	ARBA:ARBA00088984	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/CSF1R	P07333	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response|nlrp3_inflammasome		heat_shock_response:hsp12_6_shsp|nlrp3_inflammasome:pycard_self_oligomerization	coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/CSF1R	P07333	9606	GO:0008283	cell population proliferation	ARBA:ARBA00035743	NOT_ENTAILED	False	nucleokinesis			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
human/CSF1R	P07333	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CSF1R	P07333	9606	GO:0022604	regulation of cell morphogenesis	ARBA:ARBA00091911	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CSF1R	P07333	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CSF2RA	P15509	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	NOT_ENTAILED	False	kit_signaling|tnf_signaling			notch_signaling	ACCEPT
human/CSK	P41240	9606	GO:0050776	regulation of immune response	ARBA:ARBA00028647	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	coenzyme_a_biosynthesis|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CSK	P41240	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/CSNK1D	P48730	9606	GO:0030111	regulation of Wnt signaling pathway	ARBA:ARBA00027324	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
human/CSNK2A1	P68400	9606	GO:0042176	regulation of protein catabolic process	ARBA:ARBA00027460	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/CSTB	P04080	9606	GO:0045861	negative regulation of proteolysis	ARBA:ARBA00029031	NO_MODULE	False				apoptotic_execution_phase|metaphase_anaphase_transition_and_mitotic_exit|sphingolipid_de_novo_synthesis	ACCEPT
human/CTCF	P49711	9606	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|	ACCEPT
human/CTNNB1	P35222	9606	GO:0045766	positive regulation of angiogenesis	ARBA:ARBA00084376	NO_MODULE	False				erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CTNNB1	P35222	9606	GO:0050982	detection of mechanical stimulus	ARBA:ARBA00091369	NO_MODULE	False				erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/CTNNB1	P35222	9606	GO:0071681	cellular response to indole-3-methanol	ARBA:ARBA00092149	NO_MODULE	False				erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/CTPS1	P17812	9606	GO:0090407	organophosphate biosynthetic process	ARBA:ARBA00029048	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:ctp_synthase_activity	heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	MODIFY
human/CTSA	P10619	9606	GO:0031647	regulation of protein stability	ARBA:ARBA00033870	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_synthesis	ACCEPT
human/CTSA	P10619	9606	GO:1904715	negative regulation of chaperone-mediated autophagy	ARBA:ARBA00088883	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/CTSK	P43235	9606	GO:0022617	extracellular matrix disassembly	ARBA:ARBA00091895	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CTSK	P43235	9606	GO:0030574	collagen catabolic process	ARBA:ARBA00086982	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/CUL1	Q13616	9606	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	NOT_ENTAILED	True	g1_s_transition			complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
human/CUL1	Q13616	9606	GO:0070936	protein K48-linked ubiquitination	ARBA:ARBA00086253	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
human/CUL1	Q13616	9606	GO:0097193	intrinsic apoptotic signaling pathway	ARBA:ARBA00028303	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MARK_AS_OVER_ANNOTATED
human/CUL3	Q13618	9606	GO:0000209	protein polyubiquitination	ARBA:ARBA00044436	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitopha	ACCEPT
human/CUL3	Q13618	9606	GO:0000278	mitotic cell cycle	ARBA:ARBA00028458	ENTAILED	True	cell_cycle_progression|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit		cell_cycle_progression:apc_c_switch|g1_s_transition:scf_ligase|metaphase_anaphase_transition_and_mitotic_exit:apc_c	alginate_o_acetylation|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|nlrp3_inflammasome|notch_signaling|nrf_oxidative_stress_response|peroxisome-lifecyc	KEEP_AS_NON_CORE
human/CUL3	Q13618	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	NOT_ENTAILED	False	apoptotic_execution_phase|bcl2_family_momp_control			alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitopha	KEEP_AS_NON_CORE
human/CUL3	Q13618	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response|nlrp3_inflammasome|nrf_oxidative_stress_response		heat_shock_response:hsp12_6_shsp|nlrp3_inflammasome:pycard_self_oligomerization|nrf_oxidative_stress_response:cul3_scaffold|nrf_oxidative_stress_response:cul4_scaffold|nrf_oxidative_stress_response:ddb1_adaptor	alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|notch_signaling|p	KEEP_AS_NON_CORE
human/CUL3	Q13618	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	erbb2_signaling|fgfr_signaling|nlrp3_inflammasome|notch_signaling|toll_like_receptor_signaling|wnt_signaling		erbb2_signaling:nrg1_nrg1_ligand|fgfr_signaling:cbl_receptor_ubiquitination|nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:dll3_cis_inhibitor|notch_signaling:dos_coligand|notch_signaling:mib1_ligase|notch_signaling:neur_ligase|toll_like_receptor_signaling:traf6_ligase|wnt_signaling:btrc_ubiquitination|wnt_signaling:rnf43_znrf3_receptor_turnover	alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|nrf_oxidative_stress_respons	KEEP_AS_NON_CORE
human/CUL3	Q13618	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitopha	KEEP_AS_NON_CORE
human/CUL3	Q13618	9606	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_accessory_subunits|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitopha	ACCEPT
human/CUL4B	Q13620	9606	GO:0034644	cellular response to UV	ARBA:ARBA00026679	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_end	ACCEPT
human/CUL4B	Q13620	9606	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nrf_oxidative_stress_response|synaptic_vesicle_cycle|synaptic_vesicle_end	ACCEPT
human/CYP11A1	P05108	9606	GO:0006700	C21-steroid hormone biosynthetic process	ARBA:ARBA00087621	ENTAILED	True	adrenal_steroidogenesis		adrenal_steroidogenesis:cyp11a1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
human/CYP11A1	P05108	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	NOT_ENTAILED	False	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|sterol_commitment_squalene_to_lanosterol			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	KEEP_AS_NON_CORE
human/CYP11B1	P15538	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	NOT_ENTAILED	False	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|sterol_commitment_squalene_to_lanosterol			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	KEEP_AS_NON_CORE
human/CYP11B1	P15538	9606	GO:0032342	aldosterone biosynthetic process	ARBA:ARBA00095220	NO_MODULE	False				adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP11B2	P19099	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	NOT_ENTAILED	False	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|sterol_commitment_squalene_to_lanosterol			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP11B2	P19099	9606	GO:0032342	aldosterone biosynthetic process	ARBA:ARBA00095220	NO_MODULE	False				adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
human/CYP17A1	P05093	9606	GO:0008202	steroid metabolic process	ARBA:ARBA00027309	ENTAILED	False	adrenal_steroidogenesis		adrenal_steroidogenesis:cyp17a1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	KEEP_AS_NON_CORE
human/CYP17A1	P05093	9606	GO:0034308	primary alcohol metabolic process	ARBA:ARBA00029060	NOT_ENTAILED	False	retinoid_visual_cycle|thiamine_diphosphate_biosynthesis|thiamine_uptake_and_activation			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP17A1	P05093	9606	GO:0042445	hormone metabolic process	ARBA:ARBA00028011	ENTAILED	False	adrenal_steroidogenesis		adrenal_steroidogenesis:cyp17a1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	KEEP_AS_NON_CORE
human/CYP17A1	P05093	9606	GO:0120254	olefinic compound metabolic process	ARBA:ARBA00033535	NOT_ENTAILED	False	hydroxycinnamate_vanillate_catabolism|retinoid_visual_cycle			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP19A1	P11511	9606	GO:0006703	estrogen biosynthetic process	ARBA:ARBA00087624	ENTAILED	True	sex_steroid_biosynthesis		sex_steroid_biosynthesis:cyp19a1_activity	complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_upr|ubiquinone_biosynthesis	ACCEPT
human/CYP19A1	P11511	9606	GO:0008209	androgen metabolic process	ARBA:ARBA00027345	ENTAILED	False	sex_steroid_biosynthesis		sex_steroid_biosynthesis:cyp19a1_activity	complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_upr|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
human/CYP21A2	P08686	9606	GO:0006705	mineralocorticoid biosynthetic process	ARBA:ARBA00087623	NO_MODULE	False				adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
human/CYP21A2	P08686	9606	GO:0034308	primary alcohol metabolic process	ARBA:ARBA00029060	NOT_ENTAILED	False	retinoid_visual_cycle|thiamine_diphosphate_biosynthesis|thiamine_uptake_and_activation			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP21A2	P08686	9606	GO:0042180	ketone metabolic process	ARBA:ARBA00027488	NOT_ENTAILED	False	coenzyme_q10_biosynthesis|methylglyoxal_detoxification|ubiquinone_biosynthesis			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP21A2	P08686	9606	GO:0120254	olefinic compound metabolic process	ARBA:ARBA00033535	NOT_ENTAILED	False	hydroxycinnamate_vanillate_catabolism|retinoid_visual_cycle			adrenal_steroidogenesis|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP27A1	Q02318	9606	GO:0008202	steroid metabolic process	ARBA:ARBA00027309	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation		bile_acid_biosynthesis:cyp27a1_activity|bile_acid_synthesis_sidechain_conjugation:cyp27a1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
human/CYP27A1	Q02318	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	NOT_ENTAILED	False	adrenal_steroidogenesis|bacterial_unsaturated_fatty_acid_biosynthesis|carotene_backbone_biosynthesis|cholesterol_synthesis_post_lanosterol|dolichol_phosphate_sugar_donor_supply			bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP39A1	Q9NYL5	9606	GO:0007586	digestion	ARBA:ARBA00086401	NOT_ENTAILED	False	intestinal_sterol_absorption_and_efflux			bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP39A1	Q9NYL5	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	ENTAILED	False	bile_acid_biosynthesis		bile_acid_biosynthesis:cyp39a1_activity|bile_acid_biosynthesis:cyp7b1_activity	bile_acid_synthesis_ring_modification|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	KEEP_AS_NON_CORE
human/CYP7A1	P22680	9606	GO:0008206	bile acid metabolic process	ARBA:ARBA00092298	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_ring_modification		bile_acid_biosynthesis:cyp39a1_activity|bile_acid_biosynthesis:cyp7a1_activity|bile_acid_synthesis_ring_modification:cyp7a1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP7A1	P22680	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	ENTAILED	False	bile_acid_biosynthesis		bile_acid_biosynthesis:cyp39a1_activity|bile_acid_biosynthesis:cyp7a1_activity	bile_acid_synthesis_ring_modification|complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP7B1	O75881	9606	GO:0008202	steroid metabolic process	ARBA:ARBA00027309	ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_ring_modification		bile_acid_biosynthesis:cyp39a1_activity|bile_acid_biosynthesis:cyp7b1_activity|bile_acid_synthesis_ring_modification:cyp7b1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
human/CYP8B1	Q9UNU6	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	bile_acid_biosynthesis		bile_acid_biosynthesis:cyp8b1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/CYP8B1	Q9UNU6	9606	GO:0072330	monocarboxylic acid biosynthetic process	ARBA:ARBA00027175	ENTAILED	False	bile_acid_biosynthesis		bile_acid_biosynthesis:cyp8b1_activity	complex_i_assembly_factors|mitochondrial_complex_ii|mitochondrial_upr	MARK_AS_OVER_ANNOTATED
human/DBT	P11182	9606	GO:0120552	branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA	ARBA:ARBA00095351	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|branched_chain_amino_acid_catabolism	ACCEPT
human/DCX	O43602	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	ENTAILED	False	nucleokinesis		nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/DDB1	Q16531	9606	GO:0034644	cellular response to UV	ARBA:ARBA00026679	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|ciliary_transition_zone|complex_i_accessory_subunits|complex_i_assembly_factors|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis	ACCEPT
human/DDB2	Q92466	9606	GO:0034644	cellular response to UV	ARBA:ARBA00026679	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|complex_i_assembly_factors|peroxisome-lifecycle|wnt_signaling	ACCEPT
human/DDC	P20711	9606	GO:0042401	biogenic amine biosynthetic process	ARBA:ARBA00028120	ENTAILED	False	catecholamine_biosynthesis|serotonin_melatonin_biosynthesis		catecholamine_biosynthesis:ddc_activity|serotonin_melatonin_biosynthesis:ddc_serotonin	type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
human/DENR	O43583	9606	GO:0002183	cytoplasmic translational initiation	ARBA:ARBA00087684	NO_MODULE	False				er_unfolded_protein_response	KEEP_AS_NON_CORE
human/DFFA	O00273	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	MODIFY
human/DFFA	O00273	9606	GO:1902511	negative regulation of apoptotic DNA fragmentation	ARBA:ARBA00092131	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/DGUOK	Q16854	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			coenzyme_a_biosynthesis|mitochondrial_dntp_supply|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/DIABLO	Q9NR28	9606	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False					MODIFY
human/DIABLO	Q9NR28	9606	GO:0097193	intrinsic apoptotic signaling pathway	ARBA:ARBA00028303	NO_MODULE	False					ACCEPT
human/DLL1	O00548	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/DNAH17	Q9UFH2	9606	GO:0007017	microtubule-based process	ARBA:ARBA00026739	ENTAILED	False	intraflagellar_transport|nucleokinesis		intraflagellar_transport:che3_heavy_chain|nucleokinesis:dynein_nuclear_motor	hedgehog_signaling|methylcitrate_cycle|phenylacetate_catabolism|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/DNAJB1	P25685	9606	GO:0006986	response to unfolded protein	ARBA:ARBA00086617	NOT_ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr			apoptotic_execution_phase|canonical_nlrp3_inflammasome|cct_chaperonin_folding|g1_s_transition|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|neural_crest_gene_regulatory_network|nlrp3_inflammasome|notch_signaling|retinal_determination_network	ACCEPT
human/DNAJB13	P59910	9606	GO:0007017	microtubule-based process	ARBA:ARBA00026739	NOT_ENTAILED	False	intraflagellar_transport|nucleokinesis			mitochondrial_complex_ii	KEEP_AS_NON_CORE
human/DNAJB2	P25686	9606	GO:0090084	negative regulation of inclusion body assembly	ARBA:ARBA00087599	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransf	ACCEPT
human/DNAJB4	Q9UDY4	9606	GO:0006986	response to unfolded protein	ARBA:ARBA00086617	NOT_ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr			canonical_nlrp3_inflammasome|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/DNAJB5	O75953	9606	GO:0006986	response to unfolded protein	ARBA:ARBA00086617	NOT_ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr			mitochondrial_complex_ii	KEEP_AS_NON_CORE
human/DNAJB8	Q8NHS0	9606	GO:0090084	negative regulation of inclusion body assembly	ARBA:ARBA00087599	NO_MODULE	False				apoptotic_execution_phase|cct_chaperonin_folding|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v	ACCEPT
human/DNAJC1	Q96KC8	9606	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/DNAJC6	O75061	9606	GO:1905443	regulation of clathrin coat assembly	ARBA:ARBA00087398	NO_MODULE	False				heat_shock_response|synaptic_vesicle_endocytosis	ACCEPT
human/DNER	Q8NFT8	9606	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/DNM1L	O00429	9606	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ARBA:ARBA00087404	NO_MODULE	False				canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|nucleokinesis|phagocytic_engulfment|phag	ACCEPT
human/DNM1L	O00429	9606	GO:0048312	intracellular distribution of mitochondria	ARBA:ARBA00089911	NO_MODULE	False				canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|nucleokinesis|phagocytic_engulfment|phag	KEEP_AS_NON_CORE
human/DNM1L	O00429	9606	GO:0090141	positive regulation of mitochondrial fission	ARBA:ARBA00087305	NO_MODULE	False				canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|nucleokinesis|phagocytic_engulfment|phag	MODIFY
human/DNM1L	O00429	9606	GO:1903532	positive regulation of secretion by cell	ARBA:ARBA00089016	NO_MODULE	False				canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|nucleokinesis|phagocytic_engulfment|phag	MARK_AS_OVER_ANNOTATED
human/DPEP1	P16444	9606	GO:1901749	leukotriene D4 catabolic process	ARBA:ARBA00091118	NO_MODULE	False				glutathione_synthesis_gamma_glutamyl_cycle|gpi_anchor_transamidase|phenylacetate_catabolism|primary_cilium_life_cycle|protease_activation_cascade|synaptic_vesicle_endocytosis	ACCEPT
human/DPM1	O60762	9606	GO:0006506	GPI anchor biosynthetic process	ARBA:ARBA00026293	NOT_ENTAILED	True	gpi_anchor_core_glycan_assembly|gpi_anchor_ethanolamine_phosphate|gpi_anchor_glcnac_transferase|gpi_anchor_remodeling|gpi_anchor_transamidase			dolichol_phosphate_sugar_donor_supply	KEEP_AS_NON_CORE
human/DPM1	O60762	9606	GO:0043048	dolichyl monophosphate biosynthetic process	ARBA:ARBA00095221	ENTAILED	True	dolichol_phosphate_sugar_donor_supply		dolichol_phosphate_sugar_donor_supply:dpm1_activity		ACCEPT
human/DPYD	Q12882	9606	GO:0006208	pyrimidine nucleobase catabolic process	ARBA:ARBA00086398	ENTAILED	True	pyrimidine_degradation|pyrimidine_nucleotide_catabolism		pyrimidine_degradation:dpyd_activity|pyrimidine_nucleotide_catabolism:dpyd_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/DTL	Q9NZJ0	9606	GO:0006974	DNA damage response	ARBA:ARBA00026271	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			alginate_o_acetylation|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|peroxisome-lifecycle|phagocytic_engulfment|phagosome_mat	ACCEPT
human/DTL	Q9NZJ0	9606	GO:0045732	positive regulation of protein catabolic process	ARBA:ARBA00026548	NO_MODULE	False				alginate_o_acetylation|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|peroxisome-lifecycle|phagocytic_engulfment|phagosome_mat	ACCEPT
human/DUOX1	Q9NRD9	9606	GO:0009615	response to virus	ARBA:ARBA00026492	NO_MODULE	False				complex_i_assembly_factors|ferroptosis|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_ii|mitochondrial_upr|phagosome_maturation	UNDECIDED
human/DUOX1	Q9NRD9	9606	GO:0051591	response to cAMP	ARBA:ARBA00088700	NO_MODULE	False				complex_i_assembly_factors|ferroptosis|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_ii|mitochondrial_upr|phagosome_maturation	UNDECIDED
human/DUOX1	Q9NRD9	9606	GO:0071345	cellular response to cytokine stimulus	ARBA:ARBA00027915	NOT_ENTAILED	False	kit_signaling|tnf_signaling			complex_i_assembly_factors|ferroptosis|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_ii|mitochondrial_upr|phagosome_maturation	UNDECIDED
human/DUOX1	Q9NRD9	9606	GO:0090303	positive regulation of wound healing	ARBA:ARBA00026837	NO_MODULE	False				complex_i_assembly_factors|ferroptosis|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_ii|mitochondrial_upr|phagosome_maturation	KEEP_AS_NON_CORE
human/DUSP6	Q16828	9606	GO:0043409	negative regulation of MAPK cascade	ARBA:ARBA00027203	NO_MODULE	False				cerebellum_development|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	MODIFY
human/DUSP6	Q16828	9606	GO:0070371	ERK1 and ERK2 cascade	ARBA:ARBA00085205	NO_MODULE	False				cerebellum_development|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	MODIFY
human/DUT	P33316	9606	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	ARBA:ARBA00090968	ENTAILED	False	thymidylate_synthesis		thymidylate_synthesis:dut_activity	apoptotic_execution_phase|body_axis_specification|dntp_de_novo_synthesis|erbb2_signaling|fgfr_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/DUT	P33316	9606	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	ARBA:ARBA00090593	ENTAILED	False	dntp_de_novo_synthesis|thymidylate_synthesis		dntp_de_novo_synthesis:dutpase_activity|thymidylate_synthesis:dut_activity	apoptotic_execution_phase|body_axis_specification|erbb2_signaling|fgfr_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/ECHS1	P30084	9606	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	NOT_ENTAILED	True	branched_chain_amino_acid_catabolism|leucine_catabolism|valine_isoleucine_distal_catabolism			fatty_acid_beta_oxidation|methylcitrate_cycle|peroxisomal_beta_oxidation|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/ECHS1	P30084	9606	GO:0170035	L-amino acid catabolic process	ARBA:ARBA00044574	NO_MODULE	False				fatty_acid_beta_oxidation|methylcitrate_cycle|peroxisomal_beta_oxidation|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/EDEM1	Q92611	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism	ACCEPT
human/EDEM2	Q9BV94	9606	GO:0009100	glycoprotein metabolic process	ARBA:ARBA00027558	NOT_ENTAILED	False	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation|n_glycan_llo_assembly_cytoplasmic			gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/EDEM3	Q9BZQ6	9606	GO:0006516	glycoprotein catabolic process	ARBA:ARBA00085471	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/EEFSEC	P57772	9606	GO:0001514	selenocysteine incorporation	ARBA:ARBA00090133	ENTAILED	True	selenocysteine_biosynthesis_incorporation		selenocysteine_biosynthesis_incorporation:eefsec_activity|selenocysteine_biosynthesis_incorporation:selb_activity	chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/EGF	P01133	9606	GO:0007173	epidermal growth factor receptor signaling pathway	ARBA:ARBA00034174	ENTAILED	True	egfr_signaling		egfr_signaling:fly_spitz_ligand|egfr_signaling:human_egf_ligand|egfr_signaling:sos_ras_gef|egfr_signaling:worm_lin3_ligand	canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_in	ACCEPT
human/EGF	P01133	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
human/EGF	P01133	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	ACCEPT
human/EGF	P01133	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
human/EGF	P01133	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cerebellum_development		cerebellum_development:isthmic_fgf8_signal	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammaso	MARK_AS_OVER_ANNOTATED
human/EGFR	P00533	9606	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ARBA:ARBA00085202	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|g2_m_transition|gpcr_camp_pka_s	ACCEPT
human/EHD1	Q9H4M9	9606	GO:0032456	endocytic recycling	ARBA:ARBA00084270	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocyti	ACCEPT
human/EHD3	Q9NZN3	9606	GO:0032456	endocytic recycling	ARBA:ARBA00084270	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosp	ACCEPT
human/EIF2AK1	Q9BQI3	9606	GO:0006446	regulation of translational initiation	ARBA:ARBA00035061	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/EIF2AK1	Q9BQI3	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	er_unfolded_protein_response|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|nrf_oxidative_stress_response		er_unfolded_protein_response:ire1_kinase|er_unfolded_protein_response:perk_eif2a_kinase|heat_shock_response:hsp12_6_shsp|mitochondrial_upr:hri_eif2a_kinase|mitochondrial_upr:hri_heme_sensor|nlrp3_inflammasome:pycard_self_oligomerization|nrf_oxidative_stress_response:gsk3_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_b	ACCEPT
human/EIF2AK3	Q9NZJ5	9606	GO:0017148	negative regulation of translation	ARBA:ARBA00027301	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/EIF2AK3	Q9NZJ5	9606	GO:0034198	cellular response to amino acid starvation	ARBA:ARBA00090477	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_transport|kinase_phosphatase_to	UNDECIDED
human/EIF2AK3	Q9NZJ5	9606	GO:0034976	response to endoplasmic reticulum stress	ARBA:ARBA00027479	ENTAILED	False	er_unfolded_protein_response		er_unfolded_protein_response:ire1_kinase|er_unfolded_protein_response:perk_eif2a_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_transport|kinase_phosphatase_toggle|kit_signaling|metaphase_	ACCEPT
human/EIF2B4	Q9UI10	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			egfr_signaling|er_unfolded_protein_response|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/EIF2B4	Q9UI10	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			egfr_signaling|er_unfolded_protein_response|fgfr_signaling|gtpase_switch|kit_signaling|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	REMOVE
human/EIF2D	P41214	9606	GO:0043933	protein-containing complex organization	ARBA:ARBA00026287	NOT_ENTAILED	False	chylomicron_assembly_secretion|complex_i_assembly_factors|complex_iv_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii			apoptotic_execution_phase|er_unfolded_protein_response	MARK_AS_OVER_ANNOTATED
human/ELAVL1	Q15717	9606	GO:0043488	regulation of mRNA stability	ARBA:ARBA00027423	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|ciliary_transition_zone|early_metazoan_development|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|maternal_to_zygotic_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nl	MODIFY
human/ELOVL1	Q9BW60	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
human/ELOVL2	Q9NXB9	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
human/ELOVL3	Q9HB03	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
human/ELOVL4	Q9GZR5	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	ACCEPT
human/ELOVL5	Q9NYP7	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
human/ELOVL6	Q9H5J4	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
human/ELOVL7	A1L3X0	9606	GO:0030497	fatty acid elongation	ARBA:ARBA00028259	ENTAILED	True	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
human/ENDOG	Q14249	9606	GO:0006308	DNA catabolic process	ARBA:ARBA00035063	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|er_unfolded_protein_response|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism|pirna_mediated_germline_silencing	MODIFY
human/ENO3	P13929	9606	GO:0006094	gluconeogenesis	ARBA:ARBA00084701	MODULE_INCOMPLETE	True	entner_doudoroff_and_gluconeogenesis	entner_doudoroff_and_gluconeogenesis:entner_doudoroff_branch	entner_doudoroff_and_gluconeogenesis:enolase_activity	emp_glycolysis|glycolysis_payoff_phase|methylcitrate_cycle	ACCEPT
human/EPHA1	P21709	9606	GO:0030155	regulation of cell adhesion	ARBA:ARBA00027437	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ERBB2	P04626	9606	GO:0038128	ERBB2 signaling pathway	ARBA:ARBA00087673	ENTAILED	True	erbb2_signaling		erbb2_signaling:erbb2_erbb2_receptor_kinase|erbb2_signaling:nrg1_nrg1_ligand	coenzyme_a_biosynthesis|egfr_signaling|ferroptosis|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/ERBB2	P04626	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_d	KEEP_AS_NON_CORE
human/ERBB2	P04626	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_d	ACCEPT
human/ERCC4	Q92889	9606	GO:0009411	response to UV	ARBA:ARBA00028103	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|gpi_anchor_remodeling|heat_shock_response|muth_independent_mismatch_repair|nlrp3_inflammasome|phenylacetate_catabolism	ACCEPT
human/ERLIN1	O75477	9606	GO:0032933	SREBP signaling pathway	ARBA:ARBA00087340	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN1	O75477	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN1	O75477	9606	GO:0045541	negative regulation of cholesterol biosynthetic process	ARBA:ARBA00085017	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN1	O75477	9606	GO:0045717	negative regulation of fatty acid biosynthetic process	ARBA:ARBA00084177	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN2	O94905	9606	GO:0032933	SREBP signaling pathway	ARBA:ARBA00087340	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN2	O94905	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN2	O94905	9606	GO:0045541	negative regulation of cholesterol biosynthetic process	ARBA:ARBA00085017	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERLIN2	O94905	9606	GO:0045717	negative regulation of fatty acid biosynthetic process	ARBA:ARBA00084177	NO_MODULE	False				intestinal_sterol_absorption_and_efflux|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/ERN1	O75460	9606	GO:0006401	RNA catabolic process	ARBA:ARBA00027164	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaph	KEEP_AS_NON_CORE
human/ESPL1	Q14674	9606	GO:0000280	nuclear division	ARBA:ARBA00028466	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:separase	apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	MODIFY
human/ESPL1	Q14674	9606	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/FADD	Q13158	9606	GO:0001819	positive regulation of cytokine production	ARBA:ARBA00028861	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	MARK_AS_OVER_ANNOTATED
human/FADD	Q13158	9606	GO:0006952	defense response	ARBA:ARBA00026315	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nlrp3_sensor|canonical_nlrp3_inflammasome:pycard_adaptor|nlrp3_inflammasome:nlrp3_pyd_filament_adaptor|nlrp3_inflammasome:pycard_bipartite_adaptor|nlrp3_inflammasome:pycard_self_oligomerization	cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_com	MARK_AS_OVER_ANNOTATED
human/FADD	Q13158	9606	GO:0050778	positive regulation of immune response	ARBA:ARBA00028646	ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling		canonical_nlrp3_inflammasome:nlrp3_sensor|canonical_nlrp3_inflammasome:pycard_adaptor|cgas_sting_signaling:sting_signaling_adaptor|nlrp3_inflammasome:nlrp3_pyd_filament_adaptor|nlrp3_inflammasome:pycard_bipartite_adaptor|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:myd88_adaptor|tlr2_heterodimer_lipopeptide_signaling:tirap_adaptor|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif	ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engul	MARK_AS_OVER_ANNOTATED
human/FADD	Q13158	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	MARK_AS_OVER_ANNOTATED
human/FADD	Q13158	9606	GO:0097191	extrinsic apoptotic signaling pathway	ARBA:ARBA00028297	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	MODIFY
human/FADD	Q13158	9606	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ARBA:ARBA00087870	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflamma	MODIFY
human/FAF2	Q96CS3	9606	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				apoptotic_execution_phase|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyr	KEEP_AS_NON_CORE
human/FANCG	O15287	9606	GO:0006974	DNA damage response	ARBA:ARBA00026271	ENTAILED	False	bacterial_nucleotide_excision_repair		bacterial_nucleotide_excision_repair:uvra_activity	apoptotic_execution_phase	ACCEPT
human/FANCM	Q8IYD8	9606	GO:0035825	homologous recombination	ARBA:ARBA00027491	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|pir	KEEP_AS_NON_CORE
human/FAR1	Q8WVX9	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	ether_lipid_plasmalogen_biosynthesis		ether_lipid_plasmalogen_biosynthesis:far_activity	complex_i_assembly_factors|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/FAR1	Q8WVX9	9606	GO:1901568	fatty acid derivative metabolic process	ARBA:ARBA00026357	ENTAILED	False	ether_lipid_plasmalogen_biosynthesis		ether_lipid_plasmalogen_biosynthesis:far_activity	complex_i_assembly_factors|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/FAR2	Q96K12	9606	GO:0010025	wax biosynthetic process	ARBA:ARBA00091407	NO_MODULE	False				complex_i_assembly_factors|ether_lipid_plasmalogen_biosynthesis|phenylacetate_catabolism	ACCEPT
human/FAS	P25445	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling|phosphorylase_kinase_complex	ACCEPT
human/FAS	P25445	9606	GO:0097191	extrinsic apoptotic signaling pathway	ARBA:ARBA00028297	NO_MODULE	False				heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling|phosphorylase_kinase_complex	ACCEPT
human/FASN	P49327	9606	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	fatty_acid_de_novo_synthesis|type_ii_fatty_acid_synthesis		fatty_acid_de_novo_synthesis:fasn_activity|fatty_acid_de_novo_synthesis:olah_activity|type_ii_fatty_acid_synthesis:etr1_mito_reductase|type_ii_fatty_acid_synthesis:fabA_dehydratase|type_ii_fatty_acid_synthesis:fabB_condensing_activity|type_ii_fatty_acid_synthesis:fabB_unsaturated_branch|type_ii_fatty_acid_synthesis:fabD_transacylase|type_ii_fatty_acid_synthesis:fabF_condensing_activity|type_ii_fatty_acid_synthesis:fabG_reductase|type_ii_fatty_acid_synthesis:fabL_reductase|type_ii_fatty_acid_synthesis:fabZ_dehydratase|type_ii_fatty_acid_synthesis:htd2_mito_dehydratase|type_ii_fatty_acid_synthesis:mad_route_kas_condensation|type_ii_fatty_acid_synthesis:oar1_mito_reductase	alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|complex_i_assembly_factors|gpi_anchor_remodeling|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/FASN	P49327	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	fatty_acid_de_novo_synthesis|gpi_anchor_remodeling|type_ii_fatty_acid_synthesis		fatty_acid_de_novo_synthesis:fasn_activity|fatty_acid_de_novo_synthesis:olah_activity|gpi_anchor_remodeling:pgap3_activity|type_ii_fatty_acid_synthesis:etr1_mito_reductase|type_ii_fatty_acid_synthesis:fabA_dehydratase|type_ii_fatty_acid_synthesis:fabB_condensing_activity|type_ii_fatty_acid_synthesis:fabB_unsaturated_branch|type_ii_fatty_acid_synthesis:fabD_transacylase|type_ii_fatty_acid_synthesis:fabF_condensing_activity|type_ii_fatty_acid_synthesis:fabG_reductase|type_ii_fatty_acid_synthesis:fabL_reductase|type_ii_fatty_acid_synthesis:fabZ_dehydratase|type_ii_fatty_acid_synthesis:htd2_mito_dehydratase|type_ii_fatty_acid_synthesis:mad_route_kas_condensation|type_ii_fatty_acid_synthesis:oar1_mito_reductase	alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|complex_i_assembly_factors|heat_shock_response|methylcitrate_cycle|nlrp3_inflammasome|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/FBXL4	Q9UKA2	9606	GO:0000422	autophagy of mitochondrion	ARBA:ARBA00026840	ENTAILED	False	mitophagy		mitophagy:fbxl4_receptor_degradation|mitophagy:fis1_adaptor|mitophagy:fis2_adaptor|mitophagy:optn_receptor	ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nrf_oxidative_stress_response|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_	MODIFY
human/FBXL5	Q9UKA1	9606	GO:0055080	monoatomic cation homeostasis	ARBA:ARBA00027675	NO_MODULE	False				alginate_o_acetylation|peroxisome-lifecycle|wnt_signaling	KEEP_AS_NON_CORE
human/FBXL5	Q9UKA1	9606	GO:0098771	inorganic ion homeostasis	ARBA:ARBA00028888	NO_MODULE	False				alginate_o_acetylation|peroxisome-lifecycle|wnt_signaling	KEEP_AS_NON_CORE
human/FBXO43	Q4G163	9606	GO:0010948	negative regulation of cell cycle process	ARBA:ARBA00027265	NO_MODULE	False					ACCEPT
human/FBXO5	Q9UKT4	9606	GO:0010948	negative regulation of cell cycle process	ARBA:ARBA00027265	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FBXW5	Q969U6	9606	GO:0010564	regulation of cell cycle process	ARBA:ARBA00027431	NOT_ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit			metazoan_autophagosome_biogenesis	KEEP_AS_NON_CORE
human/FBXW7	Q969H0	9606	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084384	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	ACCEPT
human/FBXW7	Q969H0	9606	GO:0042752	regulation of circadian rhythm	ARBA:ARBA00088520	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	KEEP_AS_NON_CORE
human/FBXW7	Q969H0	9606	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	MARK_AS_OVER_ANNOTATED
human/FBXW7	Q969H0	9606	GO:1901800	positive regulation of proteasomal protein catabolic process	ARBA:ARBA00091269	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	KEEP_AS_NON_CORE
human/FBXW7	Q969H0	9606	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	ARBA:ARBA00088649	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	KEEP_AS_NON_CORE
human/FBXW7	Q969H0	9606	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	ARBA:ARBA00087687	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	KEEP_AS_NON_CORE
human/FBXW7	Q969H0	9606	GO:2001205	negative regulation of osteoclast development	ARBA:ARBA00088112	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_	KEEP_AS_NON_CORE
human/FCER1G	P30273	9606	GO:0050776	regulation of immune response	ARBA:ARBA00028647	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	complex_i_assembly_factors|heat_shock_response|notch_signaling	ACCEPT
human/FDFT1	P37268	9606	GO:0006694	steroid biosynthetic process	ARBA:ARBA00028726	ENTAILED	False	sterol_commitment_squalene_to_lanosterol		sterol_commitment_squalene_to_lanosterol:fdft1_activity	methionine_biosynthesis	ACCEPT
human/FDPS	P14324	9606	GO:0006695	cholesterol biosynthetic process	ARBA:ARBA00087369	NOT_ENTAILED	True	cholesterol_synthesis_post_lanosterol|sterol_commitment_squalene_to_lanosterol			apoptotic_execution_phase|isoprenoid_diphosphate_biosynthesis|methionine_biosynthesis	KEEP_AS_NON_CORE
human/FECH	P22830	9606	GO:0006785	heme B biosynthetic process	ARBA:ARBA00093713	ENTAILED	True	heme_biosynthesis		heme_biosynthesis:ferrochelatase_activity	heat_shock_response|nlrp3_inflammasome	ACCEPT
human/FEN1	P39748	9606	GO:0006310	DNA recombination	ARBA:ARBA00028026	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cgas_sting_signaling|er_unfolded_protein_response|gpi_anchor_remodeling|phenylacetate_catabolism|pirna_mediated_germline_silencing	KEEP_AS_NON_CORE
human/FERMT2	Q96AC1	9606	GO:0030335	positive regulation of cell migration	ARBA:ARBA00028907	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/FGF1	P05230	9606	GO:0001658	branching involved in ureteric bud morphogenesis	ARBA:ARBA00089877	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/FGF1	P05230	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/FGF1	P05230	9606	GO:0008543	fibroblast growth factor receptor signaling pathway	ARBA:ARBA00084988	ENTAILED	True	fgfr_signaling		fgfr_signaling:endocrine_fgf_ligand|fgfr_signaling:paracrine_fgf_ligand	canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/FGF1	P05230	9606	GO:1903672	positive regulation of sprouting angiogenesis	ARBA:ARBA00089251	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/FGF1	P05230	9606	GO:1905330	regulation of morphogenesis of an epithelium	ARBA:ARBA00087145	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/FGF1	P05230	9606	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	ARBA:ARBA00087597	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/FGF19	O95750	9606	GO:0046326	positive regulation of D-glucose import across plasma membrane	ARBA:ARBA00093151	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/FGF2	P09038	9606	GO:0001658	branching involved in ureteric bud morphogenesis	ARBA:ARBA00089877	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptos	KEEP_AS_NON_CORE
human/FGF2	P09038	9606	GO:0008543	fibroblast growth factor receptor signaling pathway	ARBA:ARBA00084988	ENTAILED	True	fgfr_signaling		fgfr_signaling:endocrine_fgf_ligand|fgfr_signaling:paracrine_fgf_ligand	canonical_nlrp3_inflammasome|cerebellum_development|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neural_ectod	ACCEPT
human/FGF2	P09038	9606	GO:1903672	positive regulation of sprouting angiogenesis	ARBA:ARBA00089251	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptos	KEEP_AS_NON_CORE
human/FGF2	P09038	9606	GO:1905330	regulation of morphogenesis of an epithelium	ARBA:ARBA00087145	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptos	KEEP_AS_NON_CORE
human/FGF2	P09038	9606	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	ARBA:ARBA00087597	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptos	KEEP_AS_NON_CORE
human/FGF21	Q9NSA1	9606	GO:0046326	positive regulation of D-glucose import across plasma membrane	ARBA:ARBA00093151	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|fgfr_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/FGFR1	P11362	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR1	P11362	9606	GO:0048699	generation of neurons	ARBA:ARBA00027116	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR1	P11362	9606	GO:0048705	skeletal system morphogenesis	ARBA:ARBA00043345	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR2	P21802	9606	GO:0033688	regulation of osteoblast proliferation	ARBA:ARBA00084763	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR2	P21802	9606	GO:0043009	chordate embryonic development	ARBA:ARBA00027425	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR2	P21802	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR2	P21802	9606	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR2	P21802	9606	GO:0048562	embryonic organ morphogenesis	ARBA:ARBA00043470	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR2	P21802	9606	GO:0048705	skeletal system morphogenesis	ARBA:ARBA00043345	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR2	P21802	9606	GO:1904888	cranial skeletal system development	ARBA:ARBA00089035	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR3	P22607	9606	GO:0001503	ossification	ARBA:ARBA00090120	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR3	P22607	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR3	P22607	9606	GO:0051216	cartilage development	ARBA:ARBA00089273	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR3	P22607	9606	GO:0060349	bone morphogenesis	ARBA:ARBA00090827	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR4	P22455	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/FGFR4	P22455	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/FGFR4	P22455	9606	GO:0070857	regulation of bile acid biosynthetic process	ARBA:ARBA00086465	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|fgfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
human/FKBP4	Q02790	9606	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			apoptotic_execution_phase|ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methylcitrate_cycle|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_en	KEEP_AS_NON_CORE
human/FKBP5	Q13451	9606	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methylcitrate_cycle|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturat	KEEP_AS_NON_CORE
human/FKBP8	Q14318	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|cct_chaperonin_folding|heat_shock_response|methylcitrate_cycle|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|phenylacetate_catabolism|phosphorylase_kinase_complex|retinoid_visual_cycle	KEEP_AS_NON_CORE
human/FRS2	Q8WU20	9606	GO:0008543	fibroblast growth factor receptor signaling pathway	ARBA:ARBA00084988	ENTAILED	True	fgfr_signaling		fgfr_signaling:endocrine_fgf_ligand|fgfr_signaling:frs2_adaptor|fgfr_signaling:frs3_adaptor|fgfr_signaling:paracrine_fgf_ligand	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucl	ACCEPT
human/FRS3	O43559	9606	GO:0008543	fibroblast growth factor receptor signaling pathway	ARBA:ARBA00084988	ENTAILED	True	fgfr_signaling		fgfr_signaling:endocrine_fgf_ligand|fgfr_signaling:frs2_adaptor|fgfr_signaling:frs3_adaptor|fgfr_signaling:paracrine_fgf_ligand	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosac	ACCEPT
human/FXN	Q16595	9606	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	ENTAILED	False	complex_i_assembly_factors		complex_i_assembly_factors:foxred1_activity|complex_i_assembly_factors:ndufaf5_activity	canonical_nlrp3_inflammasome|cobalamin_intracellular_processing|cuproptosis|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MARK_AS_OVER_ANNOTATED
human/FXN	Q16595	9606	GO:0030003	intracellular monoatomic cation homeostasis	ARBA:ARBA00028070	NO_MODULE	False				canonical_nlrp3_inflammasome|cobalamin_intracellular_processing|complex_i_assembly_factors|cuproptosis|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MARK_AS_OVER_ANNOTATED
human/FXN	Q16595	9606	GO:0098771	inorganic ion homeostasis	ARBA:ARBA00028888	NO_MODULE	False				canonical_nlrp3_inflammasome|cobalamin_intracellular_processing|complex_i_assembly_factors|cuproptosis|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MARK_AS_OVER_ANNOTATED
human/FZD7	O75084	9606	GO:0060070	canonical Wnt signaling pathway	ARBA:ARBA00026624	NO_MODULE	False				cerebellum_development|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|necroptosis|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|wnt_signaling	ACCEPT
human/G6PC1	P35575	9606	GO:0048878	chemical homeostasis	ARBA:ARBA00026985	NO_MODULE	False				gluconeogenesis|gluconeogenesis_human|gluconeogenesis_human_substrates|glucose_6_phosphatase_system|gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/GAA	P10253	9606	GO:0005980	glycogen catabolic process	ARBA:ARBA00034181	ENTAILED	True	lysosomal_glycogen_degradation		lysosomal_glycogen_degradation:gaa_activity	phenylacetate_catabolism	ACCEPT
human/GAA	P10253	9606	GO:0005984	disaccharide metabolic process	ARBA:ARBA00027065	NOT_ENTAILED	False	trey_trez_trehalose_biosynthesis			lysosomal_glycogen_degradation|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/GABARAP	O95166	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy		metazoan_autophagosome_biogenesis:gabarap_fusion|metazoan_autophagosome_biogenesis:lc3_elongation|metazoan_autophagosome_biogenesis:lgg1_early|metazoan_autophagosome_biogenesis:lgg2_late|mitophagy:atg8_family	ciliary_transition_zone|er_unfolded_protein_response|erbb2_signaling|hedgehog_signaling|nucleokinesis|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/GADD45A	P24522	9606	GO:0046330	positive regulation of JNK cascade	ARBA:ARBA00093162	NO_MODULE	False				ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/GADD45A	P24522	9606	GO:1900745	positive regulation of p38MAPK cascade	ARBA:ARBA00085720	NO_MODULE	False				ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/GADD45B	O75293	9606	GO:0046330	positive regulation of JNK cascade	ARBA:ARBA00093162	NO_MODULE	False					ACCEPT
human/GADD45B	O75293	9606	GO:1900745	positive regulation of p38MAPK cascade	ARBA:ARBA00085720	NO_MODULE	False					ACCEPT
human/GADD45G	O95257	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False					MODIFY
human/GALNT1	Q10472	9606	GO:0016266	protein O-linked glycosylation via N-acetylgalactosamine	ARBA:ARBA00086939	NO_MODULE	False					ACCEPT
human/GAS6	Q14393	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|erbb2_signaling|hedgehog_signaling|notch_signaling|phosphotyrosine_adaptor_recruitment		egfr_signaling:fly_spitz_ligand|egfr_signaling:grb2_drk_sem5_sos_adaptor|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_tail_recruitment|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand|phosphotyrosine_adaptor_recruitment:adaptor_function	apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|ferroptosis|gpcr_plc_calcium_pkc_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|nucleokinesis|oligosacch	ACCEPT
human/GAS6	Q14393	9606	GO:0016477	cell migration	ARBA:ARBA00028795	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
human/GAS6	Q14393	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
human/GAS6	Q14393	9606	GO:0031669	cellular response to nutrient levels	ARBA:ARBA00034580	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
human/GAS6	Q14393	9606	GO:0043277	apoptotic cell clearance	ARBA:ARBA00086522	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	ACCEPT
human/GAS6	Q14393	9606	GO:2000270	negative regulation of fibroblast apoptotic process	ARBA:ARBA00088175	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
human/GATA3	P23771	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|heat_shock_response|hedgehog_sign	KEEP_AS_NON_CORE
human/GATA3	P23771	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:foxd3_spec|neural_crest_gene_regulatory_network:gbx2_border|neural_crest_gene_regulatory_network:hes4_competence|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:snai1_spec|neural_crest_gene_regulatory_network:snai2_migration|neural_crest_gene_regulatory_network:snai2_spec|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|primordial_germ_cell_specification:pgc_tripartite_network	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling	ACCEPT
human/GATA3	P23771	9606	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|cerebellum_development|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal	KEEP_AS_NON_CORE
human/GATA3	P23771	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
human/GATA4	P43694	9606	GO:0007507	heart development	ARBA:ARBA00028650	ENTAILED	True	cardiac_specification_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|m	ACCEPT
human/GATA4	P43694	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|heat_shock_response|hedgehog_signaling|kit_signal	MODIFY
human/GATA4	P43694	9606	GO:0009888	tissue development	ARBA:ARBA00028065	ENTAILED	False	neural_crest_gene_regulatory_network		neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MODIFY
human/GATA4	P43694	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|primordial_germ_cell_specification:pgc_tripartite_network	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|m	MODIFY
human/GBA	P04062	9606	GO:0016241	regulation of macroautophagy	ARBA:ARBA00086966	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/GBA	P04062	9606	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	REMOVE
human/GBA	P04062	9606	GO:0042176	regulation of protein catabolic process	ARBA:ARBA00027460	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/GBA	P04062	9606	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	REMOVE
human/GBA1	P04062	9606	GO:0016241	regulation of macroautophagy	ARBA:ARBA00086966	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/GBA1	P04062	9606	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	MODIFY
human/GBA1	P04062	9606	GO:0042176	regulation of protein catabolic process	ARBA:ARBA00027460	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	MODIFY
human/GBA1	P04062	9606	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False				erbb2_signaling|glycosphingolipid_lysosomal_degradation|osmoregulated_periplasmic_glucan_biosynthesis|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/GCH1	P30793	9606	GO:0008217	regulation of blood pressure	ARBA:ARBA00027471	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|ferroptosis|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_li	KEEP_AS_NON_CORE
human/GCH1	P30793	9606	GO:0042558	pteridine-containing compound metabolic process	ARBA:ARBA00027196	ENTAILED	False	tetrahydrobiopterin_metabolism		tetrahydrobiopterin_metabolism:gch1_activity	chylomicron_assembly_secretion|egfr_signaling|ferroptosis|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_li	ACCEPT
human/GCK	P35557	9606	GO:0006006	glucose metabolic process	ARBA:ARBA00027390	MODULE_INCOMPLETE	False	entner_doudoroff_and_gluconeogenesis	entner_doudoroff_and_gluconeogenesis:entner_doudoroff_branch	entner_doudoroff_and_gluconeogenesis:glucokinase_activity	coenzyme_a_biosynthesis|emp_glycolysis|glycolysis_investment_phase|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/GCK	P35557	9606	GO:0006163	purine nucleotide metabolic process	ARBA:ARBA00026737	ENTAILED	False	emp_glycolysis|glycolysis_investment_phase		emp_glycolysis:glucokinase_entry_activity|emp_glycolysis:hexokinase_entry_activity|glycolysis_investment_phase:hexokinase_activity	coenzyme_a_biosynthesis|entner_doudoroff_and_gluconeogenesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/GCK	P35557	9606	GO:0032024	positive regulation of insulin secretion	ARBA:ARBA00092024	NO_MODULE	False				coenzyme_a_biosynthesis|emp_glycolysis|entner_doudoroff_and_gluconeogenesis|glycolysis_investment_phase|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/GCK	P35557	9606	GO:0042593	glucose homeostasis	ARBA:ARBA00087005	NO_MODULE	False				coenzyme_a_biosynthesis|emp_glycolysis|entner_doudoroff_and_gluconeogenesis|glycolysis_investment_phase|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/GCK	P35557	9606	GO:0046496	nicotinamide nucleotide metabolic process	ARBA:ARBA00028393	ENTAILED	False	emp_glycolysis|glycolysis_investment_phase		emp_glycolysis:glucokinase_entry_activity|emp_glycolysis:hexokinase_entry_activity|glycolysis_investment_phase:hexokinase_activity	coenzyme_a_biosynthesis|entner_doudoroff_and_gluconeogenesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	REMOVE
human/GCLC	P48506	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|ferroptosis|glutathione_biosynthesis|glutathione_synthesis_gamma_glutamyl_cycle|nrf_oxidative_stress_response	KEEP_AS_NON_CORE
human/GET1	O00258	9606	GO:0090150	establishment of protein localization to membrane	ARBA:ARBA00028450	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis|nucleokinesis|oligo	KEEP_AS_NON_CORE
human/GFPT1	Q06210	9606	GO:0006002	fructose 6-phosphate metabolic process	ARBA:ARBA00084568	NO_MODULE	False				hexosamine_biosynthesis|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
human/GFPT1	Q06210	9606	GO:0006112	energy reserve metabolic process	ARBA:ARBA00026613	NOT_ENTAILED	False	glycogen_biosynthesis|glycogenolysis|lysosomal_glycogen_degradation			hexosamine_biosynthesis|ubiquinone_biosynthesis	REMOVE
human/GFPT2	O94808	9606	GO:0006002	fructose 6-phosphate metabolic process	ARBA:ARBA00084568	NO_MODULE	False				hexosamine_biosynthesis|ubiquinone_biosynthesis	ACCEPT
human/GFPT2	O94808	9606	GO:0006112	energy reserve metabolic process	ARBA:ARBA00026613	NOT_ENTAILED	False	glycogen_biosynthesis|glycogenolysis|lysosomal_glycogen_degradation			hexosamine_biosynthesis|ubiquinone_biosynthesis	REMOVE
human/GGPS1	O95749	9606	GO:0006720	isoprenoid metabolic process	ARBA:ARBA00027853	ENTAILED	False	isoprenoid_diphosphate_biosynthesis		isoprenoid_diphosphate_biosynthesis:fdps_activity|isoprenoid_diphosphate_biosynthesis:fps1_spo9_ggps_activity|isoprenoid_diphosphate_biosynthesis:ggps1_activity	heat_shock_response|methionine_biosynthesis|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/GHSR	Q92847	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	fgfr_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling		fgfr_signaling:klotho_coreceptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|hedgehog_signaling:gpr161_camp_brake|hedgehog_signaling:smo_transducer|notch_signaling:notch_receptor	cerebellum_development	KEEP_AS_NON_CORE
human/GHSR	Q92847	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	fgfr_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling		fgfr_signaling:klotho_coreceptor|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|hedgehog_signaling:gpr161_camp_brake|hedgehog_signaling:smo_transducer|notch_signaling:notch_receptor	cerebellum_development	KEEP_AS_NON_CORE
human/GLA	P06280	9606	GO:0046479	glycosphingolipid catabolic process	ARBA:ARBA00092736	NOT_ENTAILED	True	glycosphingolipid_lysosomal_degradation			erbb2_signaling|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	ACCEPT
human/GLI2	P10070	9606	GO:0007224	smoothened signaling pathway	ARBA:ARBA00084926	ENTAILED	True	hedgehog_signaling		hedgehog_signaling:ci_gli_activator	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/GLI2	P10070	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|heat_shock_response|hedgehog_signaling|kit_signal	KEEP_AS_NON_CORE
human/GLI2	P10070	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	maternal_to_zygotic_transition		maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MODIFY
human/GLI3	P10071	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|kit_signaling|maternal	KEEP_AS_NON_CORE
human/GLI3	P10071	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	maternal_to_zygotic_transition		maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specificati	MODIFY
human/GLS	O94925	9606	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	glutamate_glutamine_ammonia_hub		glutamate_glutamine_ammonia_hub:gls_activity	cuproptosis|de_novo_pyrimidine_synthesis|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|vitamin_b6_plp_metabolism	KEEP_AS_NON_CORE
human/GLS2	Q9UI32	9606	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	glutamate_glutamine_ammonia_hub		glutamate_glutamine_ammonia_hub:gls_activity	cuproptosis|de_novo_pyrimidine_synthesis|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|vitamin_b6_plp_metabolism	KEEP_AS_NON_CORE
human/GLUD1	P00367	9606	GO:0006538	L-glutamate catabolic process	ARBA:ARBA00085448	NO_MODULE	False				complex_i_assembly_factors|glutamate_glutamine_ammonia_hub|heat_shock_response|nitrogen_assimilation_glutamate_glutamine|nlrp3_inflammasome	ACCEPT
human/GLUD2	P49448	9606	GO:0006538	L-glutamate catabolic process	ARBA:ARBA00085448	NO_MODULE	False				complex_i_assembly_factors|glutamate_glutamine_ammonia_hub|nitrogen_assimilation_glutamate_glutamine	ACCEPT
human/GM2A	P17900	9606	GO:0046479	glycosphingolipid catabolic process	ARBA:ARBA00092736	ENTAILED	True	glycosphingolipid_lysosomal_degradation		glycosphingolipid_lysosomal_degradation:gm2a_activity|glycosphingolipid_lysosomal_degradation:psap_activity	canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|cobalamin_intracellular_processing|dolichol_phosphate_sugar_donor_supply|keratan_chondroitin_sulfate_lysosomal_degradation|nlrp3_inflammasome|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|tlr2_heterodimer_lipopeptide_signaling|tlr	ACCEPT
human/GOT1	P17174	9606	GO:0006533	L-aspartate catabolic process	ARBA:ARBA00085434	NO_MODULE	False				aspartate_asparagine_metabolism|malate_aspartate_shuttle|ubiquinone_biosynthesis	ACCEPT
human/GOT2	P00505	9606	GO:0006533	L-aspartate catabolic process	ARBA:ARBA00085434	NO_MODULE	False				apoptotic_execution_phase|aspartate_asparagine_metabolism|malate_aspartate_shuttle|ubiquinone_biosynthesis	ACCEPT
human/GPHN	Q9NQX3	9606	GO:0050808	synapse organization	ARBA:ARBA00029184	NOT_ENTAILED	False	neurexin_transsynaptic_adhesion			ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|molybdenum_cofactor_biosynthesis|necroptosis|nlrp3_inflammasome|nucleokinesi	MARK_AS_OVER_ANNOTATED
human/GPHN	Q9NQX3	9606	GO:0072657	protein localization to membrane	ARBA:ARBA00029167	NO_MODULE	False				ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|molybdenum_cofactor_biosynthesis|necroptosis|nlrp3_inflammasome|nucleokinesi	MARK_AS_OVER_ANNOTATED
human/GPR161	Q8N6U8	9606	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	ARBA:ARBA00029026	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|ferroptosis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis	ACCEPT
human/GPR161	Q8N6U8	9606	GO:0045879	negative regulation of smoothened signaling pathway	ARBA:ARBA00086554	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|ferroptosis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis	ACCEPT
human/GPR37	O15354	9606	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ARBA:ARBA00043458	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|mitochondrial_complex_ii|notch_signaling	ACCEPT
human/GRB2	P62993	9606	GO:0007265	Ras protein signal transduction	ARBA:ARBA00044394	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophag	ACCEPT
human/GRID1	Q9ULK0	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	bcl2_family_momp_control|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|nlrp3_inflammasome|notch_signaling		bcl2_family_momp_control:bax_pore_effector|gpcr_camp_pka_signaling:beta2_adrenergic_receptor|gpcr_plc_calcium_pkc_signaling:gq_coupled_receptor|hedgehog_signaling:gpr161_camp_brake|hedgehog_signaling:smo_transducer|nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:notch_receptor	cerebellum_development|heat_shock_response|neurexin_transsynaptic_adhesion	MODIFY
human/GRID1	Q9ULK0	9606	GO:0048167	regulation of synaptic plasticity	ARBA:ARBA00033936	NO_MODULE	False				bcl2_family_momp_control|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/GRID1	Q9ULK0	9606	GO:0060078	regulation of postsynaptic membrane potential	ARBA:ARBA00026619	NO_MODULE	False				bcl2_family_momp_control|cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/GSK3B	P49841	9606	GO:0009968	negative regulation of signal transduction	ARBA:ARBA00027208	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaph	MARK_AS_OVER_ANNOTATED
human/GSK3B	P49841	9606	GO:0019082	viral protein processing	ARBA:ARBA00092097	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaph	KEEP_AS_NON_CORE
human/GSK3B	P49841	9606	GO:0031398	positive regulation of protein ubiquitination	ARBA:ARBA00028317	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaph	ACCEPT
human/GSK3B	P49841	9606	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084330	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaph	ACCEPT
human/GSK3B	P49841	9606	GO:2000077	negative regulation of type B pancreatic cell development	ARBA:ARBA00087693	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaph	KEEP_AS_NON_CORE
human/GTF2F2	P13984	9606	GO:0006368	transcription elongation by RNA polymerase II	ARBA:ARBA00086159	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection	ACCEPT
human/GUSB	P08236	9606	GO:0030214	hyaluronan catabolic process	ARBA:ARBA00085621	NO_MODULE	False				erbb2_signaling|heparan_sulfate_lysosomal_degradation|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/HAND2	P61296	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_tran	MARK_AS_OVER_ANNOTATED
human/HAO1	Q9UJM8	9606	GO:0019395	fatty acid oxidation	ARBA:ARBA00027602	NOT_ENTAILED	False	fatty_acid_beta_oxidation|peroxisomal_beta_oxidation			complex_i_assembly_factors|glyoxylate_oxalate_metabolism	MARK_AS_OVER_ANNOTATED
human/HBS1L	Q9Y450	9606	GO:0010629	negative regulation of gene expression	ARBA:ARBA00026647	NOT_ENTAILED	False	pirna_mediated_germline_silencing			chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	MARK_AS_OVER_ANNOTATED
human/HDAC6	Q9UBN7	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp	alginate_o_acetylation|apoptotic_execution_phase|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|nucleokinesis|pero	KEEP_AS_NON_CORE
human/HDAC6	Q9UBN7	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	ENTAILED	False	mitophagy		mitophagy:parkin_ligase	alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitoti	ACCEPT
human/HDAC6	Q9UBN7	9606	GO:0032886	regulation of microtubule-based process	ARBA:ARBA00033541	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitoti	ACCEPT
human/HDAC6	Q9UBN7	9606	GO:0051129	negative regulation of cellular component organization	ARBA:ARBA00026626	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitoti	KEEP_AS_NON_CORE
human/HDAC6	Q9UBN7	9606	GO:0051130	positive regulation of cellular component organization	ARBA:ARBA00026675	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitoti	KEEP_AS_NON_CORE
human/HDAC6	Q9UBN7	9606	GO:0098732	macromolecule deacylation	ARBA:ARBA00028610	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitoti	ACCEPT
human/HEXA	P06865	9606	GO:0016042	lipid catabolic process	ARBA:ARBA00028909	NOT_ENTAILED	False	fatty_acid_beta_oxidation|glycosphingolipid_lysosomal_degradation|ketone_body_oxidation|methylcitrate_cycle|peroxisomal_beta_oxidation			ferroptosis|keratan_chondroitin_sulfate_lysosomal_degradation|phenylacetate_catabolism	ACCEPT
human/HEXA	P06865	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	keratan_chondroitin_sulfate_lysosomal_degradation		keratan_chondroitin_sulfate_lysosomal_degradation:hexa_activity|keratan_chondroitin_sulfate_lysosomal_degradation:hexb_activity	ferroptosis|phenylacetate_catabolism	ACCEPT
human/HEXB	P07686	9606	GO:0016042	lipid catabolic process	ARBA:ARBA00028909	NOT_ENTAILED	False	fatty_acid_beta_oxidation|glycosphingolipid_lysosomal_degradation|ketone_body_oxidation|methylcitrate_cycle|peroxisomal_beta_oxidation			complex_i_assembly_factors|heat_shock_response|keratan_chondroitin_sulfate_lysosomal_degradation|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/HEXB	P07686	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	keratan_chondroitin_sulfate_lysosomal_degradation		keratan_chondroitin_sulfate_lysosomal_degradation:hexa_activity|keratan_chondroitin_sulfate_lysosomal_degradation:hexb_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/HK1	P19367	9606	GO:0019637	organophosphate metabolic process	ARBA:ARBA00028049	ENTAILED	False	emp_glycolysis|glycolysis_investment_phase		emp_glycolysis:glucokinase_entry_activity|emp_glycolysis:hexokinase_entry_activity|glycolysis_investment_phase:hexokinase_activity	entner_doudoroff_and_gluconeogenesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/HK1	P19367	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	emp_glycolysis|glycolysis_investment_phase		emp_glycolysis:glucokinase_entry_activity|emp_glycolysis:hexokinase_entry_activity|glycolysis_investment_phase:hexokinase_activity	coenzyme_a_biosynthesis|entner_doudoroff_and_gluconeogenesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/HLCS	P50747	9606	GO:0006768	biotin metabolic process	ARBA:ARBA00027971	ENTAILED	True	biotin_cycle		biotin_cycle:hlcs_activity	heat_shock_response|nlrp3_inflammasome	ACCEPT
human/HMBS	P08397	9606	GO:0006779	porphyrin-containing compound biosynthetic process	ARBA:ARBA00027896	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:hemc_activity	methionine_biosynthesis	ACCEPT
human/HMGB1	P09429	9606	GO:0001938	positive regulation of endothelial cell proliferation	ARBA:ARBA00091246	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	KEEP_AS_NON_CORE
human/HMGB1	P09429	9606	GO:0006259	DNA metabolic process	ARBA:ARBA00028839	ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair		bacterial_nucleotide_excision_repair:uvra_activity|bacterial_ruvabc_holliday_junction_processing:ruva_binding_activity|muth_independent_mismatch_repair:ssb_excision_scaffold	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1_s_transition|metazoan_autophagosome_biogenesis|mitochondrial_upr|neurexin_transsynaptic_adhesion|nlrp3_inflammaso	ACCEPT
human/HMGB1	P09429	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	ACCEPT
human/HMGB1	P09429	9606	GO:0010596	negative regulation of endothelial cell migration	ARBA:ARBA00092352	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	KEEP_AS_NON_CORE
human/HMGB1	P09429	9606	GO:0032722	positive regulation of chemokine production	ARBA:ARBA00085792	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	ACCEPT
human/HMGB1	P09429	9606	GO:0032732	positive regulation of interleukin-1 production	ARBA:ARBA00033917	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	ACCEPT
human/HMGB1	P09429	9606	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	KEEP_AS_NON_CORE
human/HMGB1	P09429	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	KEEP_AS_NON_CORE
human/HMGB1	P09429	9606	GO:0050792	regulation of viral process	ARBA:ARBA00091598	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	ACCEPT
human/HMGB1	P09429	9606	GO:0051052	regulation of DNA metabolic process	ARBA:ARBA00027282	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	ACCEPT
human/HMGB1	P09429	9606	GO:1903706	regulation of hemopoiesis	ARBA:ARBA00029137	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|g1	KEEP_AS_NON_CORE
human/HMGCL	P35914	9606	GO:0046951	ketone body biosynthetic process	ARBA:ARBA00084707	ENTAILED	True	ketogenesis		ketogenesis:hmgcl_activity	complex_i_accessory_subunits|leucine_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
human/HOGA1	Q86XE5	9606	GO:0009436	glyoxylate catabolic process	ARBA:ARBA00092669	NO_MODULE	False				glyoxylate_oxalate_metabolism|heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/HPD	P32754	9606	GO:0006572	L-tyrosine catabolic process	ARBA:ARBA00085483	ENTAILED	True	tyrosine_catabolism		tyrosine_catabolism:hpd_activity	bacterial_methionine_cycle|complex_i_assembly_factors|heat_shock_response|methionine_cycle|nlrp3_inflammasome	ACCEPT
human/HPRT1	P00492	9606	GO:0046100	hypoxanthine metabolic process	ARBA:ARBA00091108	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|purine_salvage_and_catabolism	ACCEPT
human/HRAS	P01112	9606	GO:0000165	MAPK cascade	ARBA:ARBA00029221	NOT_ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade			canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|gtpase_switch|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|m	ACCEPT
human/HSD17B12	Q53GQ0	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:hsd17b12_activity	complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/HSD17B3	P37058	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	sex_steroid_biosynthesis		sex_steroid_biosynthesis:hsd17b3_activity	complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
human/HSD17B4	P51659	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	fatty_acid_beta_oxidation|fatty_acid_elongation_cycle|peroxisomal_beta_oxidation		fatty_acid_beta_oxidation:lc_hydratase_activity|fatty_acid_beta_oxidation:sc_hydratase_activity|fatty_acid_elongation_cycle:hacd_activity|peroxisomal_beta_oxidation:ehhadh_activity|peroxisomal_beta_oxidation:hsd17b4_activity	complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/HSD3B2	P26439	9606	GO:0006702	androgen biosynthetic process	ARBA:ARBA00029222	NOT_ENTAILED	True	sex_steroid_biosynthesis			adrenal_steroidogenesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|complex_i_assembly_factors|methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/HSP90AA1	P07900	9606	GO:0007004	telomere maintenance via telomerase	ARBA:ARBA00091988	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling	KEEP_AS_NON_CORE
human/HSP90AA1	P07900	9606	GO:0031396	regulation of protein ubiquitination	ARBA:ARBA00028313	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling	KEEP_AS_NON_CORE
human/HSP90AA1	P07900	9606	GO:0051131	chaperone-mediated protein complex assembly	ARBA:ARBA00087767	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling	KEEP_AS_NON_CORE
human/HSP90AA1	P07900	9606	GO:1905323	telomerase holoenzyme complex assembly	ARBA:ARBA00087130	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0006402	mRNA catabolic process	ARBA:ARBA00027180	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0008285	negative regulation of cell population proliferation	ARBA:ARBA00027539	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	MARK_AS_OVER_ANNOTATED
human/HSPA1A	P0DMV8	9606	GO:0030308	negative regulation of cell growth	ARBA:ARBA00087421	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	MARK_AS_OVER_ANNOTATED
human/HSPA1A	P0DMV8	9606	GO:0031397	negative regulation of protein ubiquitination	ARBA:ARBA00086279	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	ACCEPT
human/HSPA1A	P0DMV8	9606	GO:0032757	positive regulation of interleukin-8 production	ARBA:ARBA00085873	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NOT_ENTAILED	True	nrf_oxidative_stress_response			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	ACCEPT
human/HSPA1A	P0DMV8	9606	GO:0045648	positive regulation of erythrocyte differentiation	ARBA:ARBA00084758	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0046034	ATP metabolic process	ARBA:ARBA00027108	ENTAILED	False	mitochondrial_complex_v		mitochondrial_complex_v:atpaf2_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|muth_independent_mismatch_re	MARK_AS_OVER_ANNOTATED
human/HSPA1A	P0DMV8	9606	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	ACCEPT
human/HSPA1A	P0DMV8	9606	GO:0070370	cellular heat acclimation	ARBA:ARBA00085201	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	ACCEPT
human/HSPA1A	P0DMV8	9606	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	ARBA:ARBA00085423	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0071383	cellular response to steroid hormone stimulus	ARBA:ARBA00092518	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0090063	positive regulation of microtubule nucleation	ARBA:ARBA00087613	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:0090084	negative regulation of inclusion body assembly	ARBA:ARBA00087599	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	ACCEPT
human/HSPA1A	P0DMV8	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	ARBA:ARBA00090296	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1A	P0DMV8	9606	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	ARBA:ARBA00087900	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|coenzyme_q10_biosynthesis|egfr_signaling|erbb2_signaling|g1_s_transition|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0006402	mRNA catabolic process	ARBA:ARBA00027180	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0008285	negative regulation of cell population proliferation	ARBA:ARBA00027539	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0030308	negative regulation of cell growth	ARBA:ARBA00087421	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0031397	negative regulation of protein ubiquitination	ARBA:ARBA00086279	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0032757	positive regulation of interleukin-8 production	ARBA:ARBA00085873	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NOT_ENTAILED	True	nrf_oxidative_stress_response			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	ACCEPT
human/HSPA1B	P0DMV9	9606	GO:0045648	positive regulation of erythrocyte differentiation	ARBA:ARBA00084758	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0046034	ATP metabolic process	ARBA:ARBA00027108	ENTAILED	False	mitochondrial_complex_v		mitochondrial_complex_v:atpaf2_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_c	MARK_AS_OVER_ANNOTATED
human/HSPA1B	P0DMV9	9606	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	ACCEPT
human/HSPA1B	P0DMV9	9606	GO:0070370	cellular heat acclimation	ARBA:ARBA00085201	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	ARBA:ARBA00085423	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0071383	cellular response to steroid hormone stimulus	ARBA:ARBA00092518	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0090063	positive regulation of microtubule nucleation	ARBA:ARBA00087613	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:0090084	negative regulation of inclusion body assembly	ARBA:ARBA00087599	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	ACCEPT
human/HSPA1B	P0DMV9	9606	GO:1901673	regulation of mitotic spindle assembly	ARBA:ARBA00033492	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	ARBA:ARBA00090296	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1B	P0DMV9	9606	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	ARBA:ARBA00087900	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|erbb2_signaling|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-l	KEEP_AS_NON_CORE
human/HSPA1L	P34931	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	bacterial_nucleotide_excision_repair|heat_shock_response|muth_independent_mismatch_repair|nlrp3_inflammasome		bacterial_nucleotide_excision_repair:uvrb_activity|heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity|muth_independent_mismatch_repair:mutl_atpase|nlrp3_inflammasome:nlrp3_nacht_atp_switch	apoptotic_execution_phase|cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/HSPA1L	P34931	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenyla	ACCEPT
human/HSPA2	P54652	9606	GO:0006986	response to unfolded protein	ARBA:ARBA00086617	NOT_ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenyla	ACCEPT
human/HSPA2	P54652	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenyla	ACCEPT
human/HSPA6	P17066	9606	GO:0006986	response to unfolded protein	ARBA:ARBA00086617	NOT_ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenyla	ACCEPT
human/HSPA6	P17066	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenyla	ACCEPT
human/HSPA8	P11142	9606	GO:0009968	negative regulation of signal transduction	ARBA:ARBA00027208	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	KEEP_AS_NON_CORE
human/HSPA8	P11142	9606	GO:0031647	regulation of protein stability	ARBA:ARBA00033870	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	ACCEPT
human/HSPA8	P11142	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	bacterial_nucleotide_excision_repair|er_unfolded_protein_response|heat_shock_response|mitochondrial_upr|muth_independent_mismatch_repair		bacterial_nucleotide_excision_repair:uvrb_activity|er_unfolded_protein_response:bip_folding_chaperone|heat_shock_response:hsp12_3_shsp|heat_shock_response:hsp70_foldase|heat_shock_response:hsp90_foldase|heat_shock_response:shsp_holdase_activity|mitochondrial_upr:hsp60_chaperonin|mitochondrial_upr:mthsp70_chaperone|muth_independent_mismatch_repair:mutl_atpase	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_	ACCEPT
human/HSPA8	P11142	9606	GO:0039531	regulation of cytoplasmic pattern recognition receptor signaling pathway	ARBA:ARBA00089228	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	KEEP_AS_NON_CORE
human/HSPA8	P11142	9606	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	ACCEPT
human/HSPA8	P11142	9606	GO:0043254	regulation of protein-containing complex assembly	ARBA:ARBA00086482	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	ACCEPT
human/HSPA8	P11142	9606	GO:0046034	ATP metabolic process	ARBA:ARBA00027108	ENTAILED	False	mitochondrial_complex_v		mitochondrial_complex_v:atpaf2_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	MARK_AS_OVER_ANNOTATED
human/HSPA8	P11142	9606	GO:0051129	negative regulation of cellular component organization	ARBA:ARBA00026626	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	KEEP_AS_NON_CORE
human/HSPA8	P11142	9606	GO:0071383	cellular response to steroid hormone stimulus	ARBA:ARBA00092518	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	KEEP_AS_NON_CORE
human/HSPA8	P11142	9606	GO:0072318	clathrin coat disassembly	ARBA:ARBA00044585	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	ACCEPT
human/HSPA8	P11142	9606	GO:1902903	regulation of supramolecular fiber organization	ARBA:ARBA00026728	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signali	KEEP_AS_NON_CORE
human/HSPD1	P10809	9606	GO:0001819	positive regulation of cytokine production	ARBA:ARBA00028861	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cct_chaperonin_folding|cgas_sting_signaling|coenzyme_q10_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|heat_shock_re	KEEP_AS_NON_CORE
human/HSPG2	P98160	9606	GO:0007420	brain development	ARBA:ARBA00026443	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			ciliary_transition_zone|complex_i_accessory_subunits|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|phagosome_maturation|synaptic_vesicle_cycle|synaptic	ACCEPT
human/HSPG2	P98160	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			ciliary_transition_zone|complex_i_accessory_subunits|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|phagosome_maturation|synaptic_vesicle_cycle|synaptic	KEEP_AS_NON_CORE
human/HSPG2	P98160	9606	GO:0072359	circulatory system development	ARBA:ARBA00027039	NOT_ENTAILED	False	cardiac_specification_network			ciliary_transition_zone|complex_i_accessory_subunits|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|mitophagy|phagosome_maturation|synaptic_vesicle_cycle|synaptic	ACCEPT
human/HTT	P42858	9606	GO:0007017	microtubule-based process	ARBA:ARBA00026739	NOT_ENTAILED	False	intraflagellar_transport|nucleokinesis			gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|primary_cilium_life_cycle	MARK_AS_OVER_ANNOTATED
human/HTT	P42858	9606	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|primary_cilium_life_cycle	MARK_AS_OVER_ANNOTATED
human/HTT	P42858	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/IDS	P22304	9606	GO:1901136	carbohydrate derivative catabolic process	ARBA:ARBA00026295	ENTAILED	False	heparan_sulfate_lysosomal_degradation		heparan_sulfate_lysosomal_degradation:ids_activity	gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/IDUA	P35475	9606	GO:0030200	heparan sulfate proteoglycan catabolic process	ARBA:ARBA00085487	ENTAILED	True	heparan_sulfate_lysosomal_degradation		heparan_sulfate_lysosomal_degradation:idua_activity	erbb2_signaling|phenylacetate_catabolism	ACCEPT
human/IDUA	P35475	9606	GO:0030209	dermatan sulfate proteoglycan catabolic process	ARBA:ARBA00085492	NO_MODULE	False				erbb2_signaling|heparan_sulfate_lysosomal_degradation|phenylacetate_catabolism	ACCEPT
human/IDUA	P35475	9606	GO:0030211	heparin proteoglycan catabolic process	ARBA:ARBA00085613	NO_MODULE	False				erbb2_signaling|heparan_sulfate_lysosomal_degradation|phenylacetate_catabolism	ACCEPT
human/IFIH1	Q9BYX4	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	cgas_sting_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling		cgas_sting_signaling:cglr1_dsrna_sensor|nlrp3_inflammasome:nlrp3_nacht_atp_switch|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:tlr1_tlr2_receptor|tlr2_heterodimer_lipopeptide_signaling:tlr2_tlr6_receptor	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|necroptosis|peroxisome-lifecycle|phagocytic_engulfment|phenylacetat	MODIFY
human/IFIH1	Q9BYX4	9606	GO:0051259	protein complex oligomerization	ARBA:ARBA00043446	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|necroptosis|nlrp3_inflammasome|peroxisome-life	ACCEPT
human/IFIH1	Q9BYX4	9606	GO:0140374	antiviral innate immune response	ARBA:ARBA00086315	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|necroptosis|nlrp3_inflammasome|peroxisome-life	ACCEPT
human/IFT122	Q9HBG6	9606	GO:0035720	intraciliary anterograde transport	ARBA:ARBA00098463	NO_MODULE	False				cobalamin_intracellular_processing|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/IFT122	Q9HBG6	9606	GO:0061512	protein localization to cilium	ARBA:ARBA00091714	NO_MODULE	False				cobalamin_intracellular_processing|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/IFT140	Q96RY7	9606	GO:0035721	intraciliary retrograde transport	ARBA:ARBA00092633	NO_MODULE	False				cobalamin_intracellular_processing|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/IFT140	Q96RY7	9606	GO:0060271	cilium assembly	ARBA:ARBA00027837	NOT_ENTAILED	True	ciliary_transition_zone|intraflagellar_transport			cobalamin_intracellular_processing|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/IFT172	Q9UG01	9606	GO:0044782	cilium organization	ARBA:ARBA00027540	NOT_ENTAILED	True	ciliary_transition_zone|intraflagellar_transport|primary_cilium_life_cycle				ACCEPT
human/IFT81	Q8WYA0	9606	GO:0007018	microtubule-based movement	ARBA:ARBA00033543	NOT_ENTAILED	False	intraflagellar_transport|nucleokinesis			primary_cilium_life_cycle	ACCEPT
human/IFT88	Q13099	9606	GO:1902017	regulation of cilium assembly	ARBA:ARBA00088688	NO_MODULE	False					MODIFY
human/IGFBP3	P17936	9606	GO:0014912	negative regulation of smooth muscle cell migration	ARBA:ARBA00089843	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/IGFBP3	P17936	9606	GO:0048662	negative regulation of smooth muscle cell proliferation	ARBA:ARBA00091356	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/IGFBP5	P24593	9606	GO:0014912	negative regulation of smooth muscle cell migration	ARBA:ARBA00089843	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/IGFBP5	P24593	9606	GO:0048662	negative regulation of smooth muscle cell proliferation	ARBA:ARBA00091356	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	KEEP_AS_NON_CORE
human/IKZF1	Q13422	9606	GO:0007498	mesoderm development	ARBA:ARBA00084318	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|cuproptosis|ferroptosis|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/IKZF1	Q13422	9606	GO:0030098	lymphocyte differentiation	ARBA:ARBA00086298	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|cuproptosis|ferroptosis|wnt_signaling	ACCEPT
human/IL13	P35225	9606	GO:0042116	macrophage activation	ARBA:ARBA00085939	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/IL15	P40933	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/IL21	Q9HBE4	9606	GO:0001819	positive regulation of cytokine production	ARBA:ARBA00028861	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/IL21	Q9HBE4	9606	GO:0006952	defense response	ARBA:ARBA00026315	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|notch_signaling|tgfb_smad_signaling	MARK_AS_OVER_ANNOTATED
human/IL21	Q9HBE4	9606	GO:0009615	response to virus	ARBA:ARBA00026492	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/IL21	Q9HBE4	9606	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	ARBA:ARBA00086062	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/IL21	Q9HBE4	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	MARK_AS_OVER_ANNOTATED
human/IL21	Q9HBE4	9606	GO:0051251	positive regulation of lymphocyte activation	ARBA:ARBA00028920	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/IL2RA	P01589	9606	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			notch_signaling	ACCEPT
human/IL2RA	P01589	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	NOT_ENTAILED	False	apoptotic_execution_phase|bcl2_family_momp_control			notch_signaling	MARK_AS_OVER_ANNOTATED
human/IL2RA	P01589	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				notch_signaling	ACCEPT
human/IL4	P05112	9606	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/IL4	P05112	9606	GO:0030335	positive regulation of cell migration	ARBA:ARBA00028907	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/IL4	P05112	9606	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/IL4	P05112	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	MARK_AS_OVER_ANNOTATED
human/IL4	P05112	9606	GO:0080090	regulation of primary metabolic process	ARBA:ARBA00026284	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	MARK_AS_OVER_ANNOTATED
human/IL4I1	Q96RQ9	9606	GO:0002841	negative regulation of T cell mediated immune response to tumor cell	ARBA:ARBA00090130	NO_MODULE	False				complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	ACCEPT
human/IL4I1	Q96RQ9	9606	GO:0009072	aromatic amino acid metabolic process	ARBA:ARBA00028533	NOT_ENTAILED	False	histidine_biosynthesis|histidine_catabolism|kynurenine_nad_de_novo|nad_de_novo_and_salvage_fungal|tryptophan_biosynthesis			complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	ACCEPT
human/IL4I1	Q96RQ9	9606	GO:0045591	positive regulation of regulatory T cell differentiation	ARBA:ARBA00085187	NO_MODULE	False				complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	ACCEPT
human/IL7R	P16871	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	NOT_ENTAILED	False	kit_signaling|tnf_signaling			notch_signaling	ACCEPT
human/ILK	Q13418	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|hedgehog_signaling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransf	KEEP_AS_NON_CORE
human/INPP5D	Q92835	9606	GO:0006661	phosphatidylinositol biosynthetic process	ARBA:ARBA00028655	NO_MODULE	False				gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	MODIFY
human/INPP5E	Q9NRR6	9606	GO:0019637	organophosphate metabolic process	ARBA:ARBA00028049	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	peptidoglycan_recycling|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/INS	P01308	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|insulin_receptor_signaling|methylglyoxal_detoxification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/IP6K3	Q96PC2	9606	GO:0043647	inositol phosphate metabolic process	ARBA:ARBA00087379	ENTAILED	False	myo_inositol_and_inositol_phosphate_biosynthesis		myo_inositol_and_inositol_phosphate_biosynthesis:ip6k_activity|myo_inositol_and_inositol_phosphate_biosynthesis:ppip5k_activity	coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/IP6K3	Q96PC2	9606	GO:0046488	phosphatidylinositol metabolic process	ARBA:ARBA00028373	NO_MODULE	False				coenzyme_a_biosynthesis|myo_inositol_and_inositol_phosphate_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
human/IP6K3	Q96PC2	9606	GO:0090407	organophosphate biosynthetic process	ARBA:ARBA00029048	ENTAILED	False	myo_inositol_and_inositol_phosphate_biosynthesis		myo_inositol_and_inositol_phosphate_biosynthesis:ip6k_activity|myo_inositol_and_inositol_phosphate_biosynthesis:ppip5k_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/IRAK3	Q9Y616	9606	GO:0001960	negative regulation of cytokine-mediated signaling pathway	ARBA:ARBA00091266	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_	ACCEPT
human/IRAK3	Q9Y616	9606	GO:0002684	positive regulation of immune system process	ARBA:ARBA00027011	ENTAILED	False	cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|toll_like_receptor_signaling		cgas_sting_signaling:tbk1_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:irak4_kinase|tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_tbk1|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase	coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_a	KEEP_AS_NON_CORE
human/IRAK3	Q9Y616	9606	GO:0009615	response to virus	ARBA:ARBA00026492	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_	UNDECIDED
human/IRAK3	Q9Y616	9606	GO:0043122	regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026688	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_	ACCEPT
human/IRAK3	Q9Y616	9606	GO:0045088	regulation of innate immune response	ARBA:ARBA00027944	ENTAILED	False	cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|toll_like_receptor_signaling		cgas_sting_signaling:tbk1_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:irak4_kinase|tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_tbk1|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase	coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_a	ACCEPT
human/IRAK3	Q9Y616	9606	GO:0070498	interleukin-1-mediated signaling pathway	ARBA:ARBA00084869	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_	ACCEPT
human/IRF3	Q14653	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/IRF4	Q15306	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/IRF4	Q15306	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MARK_AS_OVER_ANNOTATED
human/IRF8	Q02556	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|hedgehog_signaling|kit_s	ACCEPT
human/IRF8	Q02556	9606	GO:0098542	defense response to other organism	ARBA:ARBA00027395	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|hedgehog_signaling|kit_s	KEEP_AS_NON_CORE
human/ITGAM	P11215	9606	GO:0007159	leukocyte cell-cell adhesion	ARBA:ARBA00085300	NO_MODULE	False				cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|heat_shock_response|wnt_signaling	ACCEPT
human/ITGAM	P11215	9606	GO:0033631	cell-cell adhesion mediated by integrin	ARBA:ARBA00095216	NO_MODULE	False				cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|heat_shock_response|wnt_signaling	ACCEPT
human/ITGAM	P11215	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|heat_shock_response|wnt_signaling	REMOVE
human/ITGB1	P05556	9606	GO:0001525	angiogenesis	ARBA:ARBA00090097	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	KEEP_AS_NON_CORE
human/ITGB1	P05556	9606	GO:0007160	cell-matrix adhesion	ARBA:ARBA00085356	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	ACCEPT
human/ITGB1	P05556	9606	GO:0007229	integrin-mediated signaling pathway	ARBA:ARBA00084939	NOT_ENTAILED	True	integrin_fak_src_signaling			complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	ACCEPT
human/ITGB1	P05556	9606	GO:0034113	heterotypic cell-cell adhesion	ARBA:ARBA00090976	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	KEEP_AS_NON_CORE
human/ITGB1	P05556	9606	GO:0048333	mesodermal cell differentiation	ARBA:ARBA00089498	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	MARK_AS_OVER_ANNOTATED
human/ITGB1	P05556	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	MARK_AS_OVER_ANNOTATED
human/ITGB1	P05556	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	MARK_AS_OVER_ANNOTATED
human/ITGB1	P05556	9606	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway	ARBA:ARBA00085719	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|ferroptosis|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis	KEEP_AS_NON_CORE
human/ITK	Q08881	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	integrin_fak_src_signaling|kit_signaling		integrin_fak_src_signaling:fak_kinase|integrin_fak_src_signaling:src_kinase|kit_signaling:lyn_src_family_kinase	coenzyme_a_biosynthesis|g2_m_transition|kinase_phosphatase_toggle|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/ITK	Q08881	9606	GO:0042110	T cell activation	ARBA:ARBA00085932	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/JAG1	P78504	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|cerebellum_development|complex_i_accessory_subunits|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neural_ectoderm_anteroposterior_specification|neurexi	MARK_AS_OVER_ANNOTATED
human/JAG1	P78504	9606	GO:0045596	negative regulation of cell differentiation	ARBA:ARBA00033859	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_accessory_subunits|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neural_ectoderm_anteroposterior_specification|neurexi	KEEP_AS_NON_CORE
human/JAG1	P78504	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cerebellum_development		cerebellum_development:isthmic_fgf8_signal	canonical_nlrp3_inflammasome|complex_i_accessory_subunits|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesio	KEEP_AS_NON_CORE
human/JAG1	P78504	9606	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cerebellum_development		cerebellum_development:isthmic_fgf8_signal	canonical_nlrp3_inflammasome|complex_i_accessory_subunits|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesio	KEEP_AS_NON_CORE
human/JAK1	P23458	9606	GO:0007259	cell surface receptor signaling pathway via JAK-STAT	ARBA:ARBA00034574	NO_MODULE	False				coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/JAK1	P23458	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:lyn_src_family_kinase	coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/JAK1	P23458	9606	GO:0022407	regulation of cell-cell adhesion	ARBA:ARBA00028251	NO_MODULE	False				coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/JAK1	P23458	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/JAK1	P23458	9606	GO:0098761	cellular response to interleukin-7	ARBA:ARBA00091517	NO_MODULE	False				coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KCTD10	Q9H3F6	9606	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|notch_signaling|nrf_oxidative_stress_response|nucleokinesis|oligosacchar	ACCEPT
human/KIF1A	Q12756	9606	GO:0010970	transport along microtubule	ARBA:ARBA00044586	ENTAILED	False	intraflagellar_transport|nucleokinesis		intraflagellar_transport:kinesin_ii_motor|intraflagellar_transport:osm3_motor|nucleokinesis:dcx_perinuclear_microtubule_stabilizer|nucleokinesis:kif1a_basal_nuclear_motor	bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|heat_shock_response|hedgehog_signaling|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_	ACCEPT
human/KIF24	Q5T7B8	9606	GO:0007019	microtubule depolymerization	ARBA:ARBA00092022	NO_MODULE	False				ciliary_transition_zone|heat_shock_response|hedgehog_signaling|methylcitrate_cycle|nlrp3_inflammasome|nucleokinesis|phenylacetate_catabolism|primary_cilium_life_cycle	ACCEPT
human/KIF2A	O00139	9606	GO:0000070	mitotic sister chromatid segregation	ARBA:ARBA00033588	NO_MODULE	False				bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocy	KEEP_AS_NON_CORE
human/KIF2A	O00139	9606	GO:0007019	microtubule depolymerization	ARBA:ARBA00092022	NO_MODULE	False				bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocy	ACCEPT
human/KIF3A	Q9Y496	9606	GO:0008104	intracellular protein localization	ARBA:ARBA00028253	NO_MODULE	False				bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|hedgehog_signaling|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_cataboli	KEEP_AS_NON_CORE
human/KIF3A	Q9Y496	9606	GO:0010970	transport along microtubule	ARBA:ARBA00044586	ENTAILED	False	intraflagellar_transport|nucleokinesis		intraflagellar_transport:kinesin_ii_motor|intraflagellar_transport:osm3_motor|nucleokinesis:dcx_perinuclear_microtubule_stabilizer|nucleokinesis:kif1a_basal_nuclear_motor	bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|hedgehog_signaling|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_v	ACCEPT
human/KIF3B	O15066	9606	GO:0008088	axo-dendritic transport	ARBA:ARBA00093058	NO_MODULE	False				bacterial_nucleotide_excision_repair|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|hedgehog_signaling|intraflagellar_transport|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_cataboli	KEEP_AS_NON_CORE
human/KIFAP3	Q92845	9606	GO:0010970	transport along microtubule	ARBA:ARBA00044586	NOT_ENTAILED	False	intraflagellar_transport|nucleokinesis			complex_i_assembly_factors	ACCEPT
human/KIT	P10721	9606	GO:0002720	positive regulation of cytokine production involved in immune response	ARBA:ARBA00090392	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0006935	chemotaxis	ARBA:ARBA00027707	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0008406	gonad development	ARBA:ARBA00028782	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0016477	cell migration	ARBA:ARBA00028795	NOT_ENTAILED	False	nucleokinesis			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0030097	hemopoiesis	ARBA:ARBA00028409	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/KIT	P10721	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	ACCEPT
human/KIT	P10721	9606	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KIT	P10721	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/KITLG	P21583	9606	GO:0003006	developmental process involved in reproduction	ARBA:ARBA00026397	NOT_ENTAILED	False	primordial_germ_cell_specification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/KITLG	P21583	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	KEEP_AS_NON_CORE
human/KRAS	P01116	9606	GO:0000165	MAPK cascade	ARBA:ARBA00029221	NOT_ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade			chylomicron_assembly_secretion|complex_i_assembly_factors|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|s	ACCEPT
human/LAMP1	P11279	9606	GO:0007042	lysosomal lumen acidification	ARBA:ARBA00092063	NO_MODULE	False				apoptotic_execution_phase	ACCEPT
human/LATS1	O95835	9606	GO:0035329	hippo signaling	ARBA:ARBA00091361	ENTAILED	True	hippo_signaling		hippo_signaling:lats_kinase|hippo_signaling:mst_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_au	ACCEPT
human/LATS1	O95835	9606	GO:0044772	mitotic cell cycle phase transition	ARBA:ARBA00027525	ENTAILED	False	g2_m_transition|metaphase_anaphase_transition_and_mitotic_exit		g2_m_transition:cak1|g2_m_transition:checkpoint_kinase|g2_m_transition:greatwall_kinase|g2_m_transition:polo_kinase|metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nf	KEEP_AS_NON_CORE
human/LATS1	O95835	9606	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
human/LCK	P06239	9606	GO:0002429	immune response-activating cell surface receptor signaling pathway	ARBA:ARBA00089168	NOT_ENTAILED	False	tlr4_md2_lps_signaling			canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transit	ACCEPT
human/LCK	P06239	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization	coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan	KEEP_AS_NON_CORE
human/LCK	P06239	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transit	MARK_AS_OVER_ANNOTATED
human/LCP2	Q13094	9606	GO:0002376	immune system process	ARBA:ARBA00027799	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	MODIFY
human/LDLR	P01130	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	NOT_ENTAILED	False	adrenal_steroidogenesis|bacterial_unsaturated_fatty_acid_biosynthesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation			ciliary_transition_zone|cobalamin_absorption_transport|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|mitophagy|nlrp3_inflammasome|phagosome_maturation|synaptic_vesicle_endocytosis|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/LDLR	P01130	9606	GO:0034383	low-density lipoprotein particle clearance	ARBA:ARBA00093169	ENTAILED	True	ldl_receptor_mediated_endocytosis		ldl_receptor_mediated_endocytosis:ldlr_receptor	ciliary_transition_zone|cobalamin_absorption_transport|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|synaptic_vesicle_endocytosis|wnt_signaling	ACCEPT
human/LDLR	P01130	9606	GO:0042632	cholesterol homeostasis	ARBA:ARBA00086791	NO_MODULE	False				ciliary_transition_zone|cobalamin_absorption_transport|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|mitophagy|nlrp3_inflammasome|phagosome_maturation|synaptic_vesicle_endocytosis|wnt_signaling	ACCEPT
human/LDLR	P01130	9606	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				ciliary_transition_zone|cobalamin_absorption_transport|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|mitophagy|nlrp3_inflammasome|phagosome_maturation|synaptic_vesicle_endocytosis|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/LGALS3	P17931	9606	GO:0042129	regulation of T cell proliferation	ARBA:ARBA00085953	NO_MODULE	False				apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|g2_m_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neure	KEEP_AS_NON_CORE
human/LGALS3	P17931	9606	GO:0046636	negative regulation of alpha-beta T cell activation	ARBA:ARBA00091948	NO_MODULE	False				apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|g2_m_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neure	KEEP_AS_NON_CORE
human/LGALS3	P17931	9606	GO:0070232	regulation of T cell apoptotic process	ARBA:ARBA00097057	NO_MODULE	False				apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|g2_m_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neure	KEEP_AS_NON_CORE
human/LGALS3	P17931	9606	GO:0071677	positive regulation of mononuclear cell migration	ARBA:ARBA00092096	NO_MODULE	False				apoptotic_execution_phase|body_axis_specification|canonical_nlrp3_inflammasome|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|ferroptosis|g2_m_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neure	KEEP_AS_NON_CORE
human/LIMD1	Q9UGP4	9606	GO:0001666	response to hypoxia	ARBA:ARBA00027678	NO_MODULE	False				g1_s_transition|notch_signaling|retinal_determination_network	ACCEPT
human/LIMD1	Q9UGP4	9606	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	ARBA:ARBA00091152	NO_MODULE	False				g1_s_transition|notch_signaling|retinal_determination_network	ACCEPT
human/LIMD1	Q9UGP4	9606	GO:0035331	negative regulation of hippo signaling	ARBA:ARBA00091342	NO_MODULE	False				g1_s_transition|notch_signaling|retinal_determination_network	ACCEPT
human/LNPEP	Q9UIQ6	9606	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	ARBA:ARBA00088849	NO_MODULE	False				phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/LOXHD1	Q8IVV2	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False					ACCEPT
human/LOXL3	P58215	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	KEEP_AS_NON_CORE
human/LOXL3	P58215	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	KEEP_AS_NON_CORE
human/LPAR1	Q92633	9606	GO:0007204	positive regulation of cytosolic calcium ion concentration	ARBA:ARBA00028136	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/LPAR2	Q9HBW0	9606	GO:0007204	positive regulation of cytosolic calcium ion concentration	ARBA:ARBA00028136	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|primary_cilium_life_cycle	ACCEPT
human/LPAR3	Q9UBY5	9606	GO:0007204	positive regulation of cytosolic calcium ion concentration	ARBA:ARBA00028136	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/LPCAT2	Q7L5N7	9606	GO:0006650	glycerophospholipid metabolic process	ARBA:ARBA00028631	ENTAILED	False	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:agpat2_activity|triacylglycerol_biosynthesis:loa1_lpaat_activity|triacylglycerol_biosynthesis:mboat_lpaat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|ferroptosis|gpcr_plc_calcium_pkc_signaling	KEEP_AS_NON_CORE
human/LPL	P06858	9606	GO:0006641	triglyceride metabolic process	ARBA:ARBA00028707	ENTAILED	False	triacylglycerol_lipolysis		triacylglycerol_lipolysis:atgl_activity	ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	ACCEPT
human/LPL	P06858	9606	GO:0016042	lipid catabolic process	ARBA:ARBA00028909	ENTAILED	False	triacylglycerol_lipolysis		triacylglycerol_lipolysis:atgl_activity	ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	ACCEPT
human/LRP1	Q07954	9606	GO:0001523	retinoid metabolic process	ARBA:ARBA00028293	NOT_ENTAILED	False	retinoid_visual_cycle			apoptotic_execution_phase|cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP1	Q07954	9606	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	ENTAILED	True	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|ldl_receptor_mediated_endocytosis:ldlr_receptor	apoptotic_execution_phase|complex_i_assembly_factors|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|phagocytic_engulfment|synaptic_vesicle_endocytosis|wnt_signaling	ACCEPT
human/LRP1	Q07954	9606	GO:0030100	regulation of endocytosis	ARBA:ARBA00085851	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP1	Q07954	9606	GO:0051050	positive regulation of transport	ARBA:ARBA00034593	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis|wnt_signaling	ACCEPT
human/LRP1	Q07954	9606	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP10	Q7Z4F1	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|ldl_receptor_mediated_endocytosis:ldlr_receptor	wnt_signaling	ACCEPT
human/LRP12	Q9Y561	9606	GO:0001764	neuron migration	ARBA:ARBA00089626	NO_MODULE	False				cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|ldl_receptor_mediated_endocytosis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP12	Q9Y561	9606	GO:0031175	neuron projection development	ARBA:ARBA00026765	NO_MODULE	False				cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|ldl_receptor_mediated_endocytosis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP1B	Q9NZR2	9606	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	ENTAILED	True	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|ldl_receptor_mediated_endocytosis:ldlr_receptor	gpcr_plc_calcium_pkc_signaling|wnt_signaling	ACCEPT
human/LRP2	P98164	9606	GO:0001523	retinoid metabolic process	ARBA:ARBA00028293	NOT_ENTAILED	False	retinoid_visual_cycle			cobalamin_absorption_transport|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_ii|wnt_signaling	KEEP_AS_NON_CORE
human/LRP2	P98164	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	gpcr_plc_calcium_pkc_signaling|wnt_signaling		gpcr_plc_calcium_pkc_signaling:calmodulin_sensor|wnt_signaling:wls_wnt_secretion	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|mitochondrial_complex_ii	MARK_AS_OVER_ANNOTATED
human/LRP2	P98164	9606	GO:0030001	metal ion transport	ARBA:ARBA00028072	NO_MODULE	False				cobalamin_absorption_transport|gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_ii|wnt_signaling	KEEP_AS_NON_CORE
human/LRP2	P98164	9606	GO:0051180	vitamin transport	ARBA:ARBA00026766	ENTAILED	False	cobalamin_absorption_transport		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity	gpcr_plc_calcium_pkc_signaling|ldl_receptor_mediated_endocytosis|mitochondrial_complex_ii|wnt_signaling	KEEP_AS_NON_CORE
human/LRP3	O75074	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|snare_fusion_cycle|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis				KEEP_AS_NON_CORE
human/LRP4	O75096	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/LRP4	O75096	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0009887	animal organ morphogenesis	ARBA:ARBA00028067	NO_MODULE	False				fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0045667	regulation of osteoblast differentiation	ARBA:ARBA00084601	NO_MODULE	False				fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP5	O75197	9606	GO:0045787	positive regulation of cell cycle	ARBA:ARBA00026693	NO_MODULE	False				fgfr_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|ldl_receptor_mediated_endocytosis:ldlr_receptor	apoptotic_execution_phase|erbb2_signaling|fgfr_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0030901	midbrain development	ARBA:ARBA00088343	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0043009	chordate embryonic development	ARBA:ARBA00027425	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0045787	positive regulation of cell cycle	ARBA:ARBA00026693	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0048646	anatomical structure formation involved in morphogenesis	ARBA:ARBA00028539	NOT_ENTAILED	False	germ_layer_specification			apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP6	O75581	9606	GO:0071542	dopaminergic neuron differentiation	ARBA:ARBA00092424	NO_MODULE	False				apoptotic_execution_phase|cobalamin_absorption_transport|erbb2_signaling|fgfr_signaling|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/LRP8	Q14114	9606	GO:0006897	endocytosis	ARBA:ARBA00027119	ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity|ldl_receptor_mediated_endocytosis:ldlr_receptor	complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	ACCEPT
human/LRP8	Q14114	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling		gpcr_plc_calcium_pkc_signaling:calmodulin_sensor|notch_signaling:notch_receptor|wnt_signaling:wls_wnt_secretion	cobalamin_absorption_transport|complex_i_assembly_factors|ldl_receptor_mediated_endocytosis	MODIFY
human/LRRK2	Q5S007	9606	GO:0007030	Golgi organization	ARBA:ARBA00091973	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	ACCEPT
human/LRRK2	Q5S007	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|hedgehog_signaling|insulin_receptor_signaling|phosphotyrosine_adaptor_recruitment|tlr4_md2_lps_signaling|tnf_signaling|wnt_signaling		egfr_signaling:grb2_drk_sem5_sos_adaptor|egfr_signaling:raf_map3k|egfr_signaling:ras_switch|hedgehog_signaling:ck1_processive_kinase|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:fused_family_kinase|hedgehog_signaling:gsk3_processive_kinase|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_tail_recruitment|insulin_receptor_signaling:akt_effector|phosphotyrosine_adaptor_recruitment:adaptor_function|tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tbk1|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif|tnf_signaling:tak1_complex_ikkbeta_kinase|tnf_signaling:tak1_map3k|wnt_signaling:destruction_complex|wnt_signaling:dvl_recruitment|wnt_signaling:signalosome_assembly	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	MARK_AS_OVER_ANNOTATED
human/LRRK2	Q5S007	9606	GO:0009968	negative regulation of signal transduction	ARBA:ARBA00027208	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis|vesicle_coat_budding		synaptic_vesicle_cycle:cycle_dynamin|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:dynamin_gtpase|synaptic_vesicle_endocytosis:ultrafast_dynamin_retrieval|synaptic_vesicle_exocytosis:complexin_clamp|synaptic_vesicle_exocytosis:munc13_priming_factor|synaptic_vesicle_exocytosis:munc18_sm_protein|synaptic_vesicle_exocytosis:rim_active_zone_effector|vesicle_coat_budding:cargo_adaptor_activity	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	ACCEPT
human/LRRK2	Q5S007	9606	GO:0030162	regulation of proteolysis	ARBA:ARBA00027404	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0030182	neuron differentiation	ARBA:ARBA00027575	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	MARK_AS_OVER_ANNOTATED
human/LRRK2	Q5S007	9606	GO:0035640	exploration behavior	ARBA:ARBA00093010	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	MARK_AS_OVER_ANNOTATED
human/LRRK2	Q5S007	9606	GO:0042391	regulation of membrane potential	ARBA:ARBA00028934	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	nucleokinesis		nucleokinesis:cdk5_p35_kinase|nucleokinesis:cenpf_nuclear_pore_nude_recruiter|nucleokinesis:dcx_perinuclear_microtubule_stabilizer	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	MARK_AS_OVER_ANNOTATED
human/LRRK2	Q5S007	9606	GO:0050804	modulation of chemical synaptic transmission	ARBA:ARBA00029187	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0051247	positive regulation of protein metabolic process	ARBA:ARBA00028881	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:0060627	regulation of vesicle-mediated transport	ARBA:ARBA00029251	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	ACCEPT
human/LRRK2	Q5S007	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LRRK2	Q5S007	9606	GO:1904887	Wnt signalosome assembly	ARBA:ARBA00089044	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|chylomicron_assembly_secretion|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transi	KEEP_AS_NON_CORE
human/LSS	P48449	9606	GO:0006695	cholesterol biosynthetic process	ARBA:ARBA00087369	ENTAILED	True	sterol_commitment_squalene_to_lanosterol		sterol_commitment_squalene_to_lanosterol:lss_activity	methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
human/LY96	Q9Y6Y9	9606	GO:0002221	pattern recognition receptor signaling pathway	ARBA:ARBA00033911	ENTAILED	False	tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling		tlr2_heterodimer_lipopeptide_signaling:tlr1_tlr2_receptor|tlr2_heterodimer_lipopeptide_signaling:tlr2_tlr6_receptor|tlr4_md2_lps_signaling:tlr4_md2_lps_receptor	erbb2_signaling|fgfr_signaling|necroptosis|phagocytic_engulfment|primary_cilium_life_cycle	ACCEPT
human/LYN	P07948	9606	GO:0002758	innate immune response-activating signaling pathway	ARBA:ARBA00034398	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	ARBA:ARBA00090107	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0006952	defense response	ARBA:ARBA00026315	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	ARBA:ARBA00088071	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0050900	leukocyte migration	ARBA:ARBA00091273	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0071345	cellular response to cytokine stimulus	ARBA:ARBA00027915	ENTAILED	False	kit_signaling		kit_signaling:lyn_src_family_kinase	canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0071396	cellular response to lipid	ARBA:ARBA00027803	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/LYN	P07948	9606	GO:0120035	regulation of plasma membrane bounded cell projection organization	ARBA:ARBA00028050	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|primary_cilium_life_cycl	KEEP_AS_NON_CORE
human/MAD2L1	Q13257	9606	GO:0051783	regulation of nuclear division	ARBA:ARBA00027796	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/MAD2L1	Q13257	9606	GO:1901991	negative regulation of mitotic cell cycle phase transition	ARBA:ARBA00044401	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome	ACCEPT
human/MAD2L2	Q9UI95	9606	GO:0010717	regulation of epithelial to mesenchymal transition	ARBA:ARBA00085208	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|notch_signaling|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phos	KEEP_AS_NON_CORE
human/MAGT1	Q9H0U3	9606	GO:0006487	protein N-linked glycosylation	ARBA:ARBA00085866	NOT_ENTAILED	True	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|n_glycan_llo_assembly_cytoplasmic|n_glycan_llo_assembly_lumenal|oligosaccharyltransferase_complex				ACCEPT
human/MAN1B1	Q9UKM7	9606	GO:0009100	glycoprotein metabolic process	ARBA:ARBA00027558	NOT_ENTAILED	False	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation|n_glycan_llo_assembly_cytoplasmic			gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/MAN1B1	Q9UKM7	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|phenylacetate_catabolism	ACCEPT
human/MAP1LC3B	Q9GZQ8	9606	GO:0000045	autophagosome assembly	ARBA:ARBA00088808	NO_MODULE	False				ciliary_transition_zone|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/MAP1LC3B	Q9GZQ8	9606	GO:0000422	autophagy of mitochondrion	ARBA:ARBA00026840	ENTAILED	False	mitophagy		mitophagy:atg8_family	ciliary_transition_zone|metazoan_autophagosome_biogenesis|nucleokinesis|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/MAP1LC3B	Q9GZQ8	9606	GO:0097352	autophagosome maturation	ARBA:ARBA00033540	NO_MODULE	False				ciliary_transition_zone|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/MAP2K1	Q02750	9606	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling	REMOVE
human/MAP2K1	Q02750	9606	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling	KEEP_AS_NON_CORE
human/MAP2K1	Q02750	9606	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling	KEEP_AS_NON_CORE
human/MAP2K2	P36507	9606	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signa	UNDECIDED
human/MAP2K2	P36507	9606	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signa	UNDECIDED
human/MAP2K2	P36507	9606	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_accessory_subunits|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signa	UNDECIDED
human/MAP2K3	P46734	9606	GO:0031098	stress-activated protein kinase signaling cascade	ARBA:ARBA00035552	ENTAILED	False	jnk_cascade|p38_cascade		jnk_cascade:jnk_map2k_activity|p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/MAP2K3	P46734	9606	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/MAP2K3	P46734	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/MAP2K3	P46734	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/MAP2K4	P45985	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|integrin_fak_src_signaling		egfr_signaling:mek_map2k|integrin_fak_src_signaling:src_kinase	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/MAP2K4	P45985	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	jnk_cascade|nrf_oxidative_stress_response|p38_cascade		jnk_cascade:jnk_map2k_activity|nrf_oxidative_stress_response:sek1_map2k|p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
human/MAP2K5	Q13163	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	egfr_signaling|erk5_cascade|integrin_fak_src_signaling|jnk_cascade|mapk_relay|p38_cascade		egfr_signaling:mek_map2k|erk5_cascade:erk5_map2k_activity|integrin_fak_src_signaling:src_kinase|jnk_cascade:jnk_map2k_activity|mapk_relay:map2k_activity|p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|g2_m_transition|kinase_phosphatase_toggle|nrf_oxidative_stress_response|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
human/MAP2K6	P52564	9606	GO:0031098	stress-activated protein kinase signaling cascade	ARBA:ARBA00035552	ENTAILED	False	jnk_cascade|p38_cascade		jnk_cascade:jnk_map2k_activity|p38_cascade:p38_map2k_activity	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_tra	ACCEPT
human/MAP2K6	P52564	9606	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map2k_activity	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_tra	ACCEPT
human/MAP2K6	P52564	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_tra	KEEP_AS_NON_CORE
human/MAP2K6	P52564	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_tra	MARK_AS_OVER_ANNOTATED
human/MAP2K7	O14733	9606	GO:0031098	stress-activated protein kinase signaling cascade	ARBA:ARBA00035552	ENTAILED	False	jnk_cascade|p38_cascade		jnk_cascade:jnk_map2k_activity|p38_cascade:p38_map2k_activity	coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/MAP2K7	O14733	9606	GO:0043410	positive regulation of MAPK cascade	ARBA:ARBA00027228	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/MAP2K7	O14733	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metazoan_autophagosome_biogenesis|nrf_oxidative_stress_response|p38_cascade|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/MAP3K1	Q13233	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|fgfr_signaling|hedgehog_signaling|insulin_receptor_signaling|notch_signaling|tlr4_md2_lps_signaling|tnf_signaling|wnt_signaling		egfr_signaling:raf_map3k|fgfr_signaling:cbl_receptor_ubiquitination|hedgehog_signaling:ck1_processive_kinase|hedgehog_signaling:fused_family_kinase|hedgehog_signaling:gsk3_processive_kinase|insulin_receptor_signaling:akt_effector|notch_signaling:mib1_ligase|notch_signaling:neur_ligase|tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_tbk1|tnf_signaling:tak1_complex_ikkbeta_kinase|tnf_signaling:tak1_map3k|wnt_signaling:btrc_ubiquitination|wnt_signaling:destruction_complex|wnt_signaling:rnf43_znrf3_receptor_turnover	alginate_o_acetylation|cell_cycle_progression|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erk5_cascade|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hippo_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|m	KEEP_AS_NON_CORE
human/MAP3K2	Q9Y2U5	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	cgas_sting_signaling|er_unfolded_protein_response|erk5_cascade|hippo_signaling|jnk_cascade|mapk_relay|nfkb_canonical_signaling|nlr_signaling|p38_cascade		cgas_sting_signaling:tbk1_kinase|er_unfolded_protein_response:ire1_kinase|erk5_cascade:erk5_map3k_activity|hippo_signaling:lats_kinase|hippo_signaling:mst_kinase|jnk_cascade:jnk_map3k_activity|mapk_relay:map3k_activity|nfkb_canonical_signaling:ikk_kinase|nfkb_canonical_signaling:tak1_complex_ikkbeta_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlr_signaling:tak1_map3k|p38_cascade:p38_map3k_activity	coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|ne	MODIFY
human/MAP3K3	Q99759	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	cgas_sting_signaling|er_unfolded_protein_response|erk5_cascade|hippo_signaling|jnk_cascade|mapk_relay|nfkb_canonical_signaling|nlr_signaling|p38_cascade		cgas_sting_signaling:tbk1_kinase|er_unfolded_protein_response:ire1_kinase|erk5_cascade:erk5_map3k_activity|hippo_signaling:lats_kinase|hippo_signaling:mst_kinase|jnk_cascade:jnk_map3k_activity|mapk_relay:map3k_activity|nfkb_canonical_signaling:ikk_kinase|nfkb_canonical_signaling:tak1_complex_ikkbeta_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlr_signaling:tak1_map3k|p38_cascade:p38_map3k_activity	coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|ne	MODIFY
human/MAPK1	P28482	9606	GO:0007173	epidermal growth factor receptor signaling pathway	ARBA:ARBA00034174	ENTAILED	True	egfr_signaling		egfr_signaling:erk_mapk|egfr_signaling:grb2_drk_sem5_adaptor	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_togg	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0010759	positive regulation of macrophage chemotaxis	ARBA:ARBA00085235	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0032206	positive regulation of telomere maintenance	ARBA:ARBA00047239	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	MARK_AS_OVER_ANNOTATED
human/MAPK1	P28482	9606	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	MARK_AS_OVER_ANNOTATED
human/MAPK1	P28482	9606	GO:0034198	cellular response to amino acid starvation	ARBA:ARBA00090477	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0051403	stress-activated MAPK cascade	ARBA:ARBA00035551	ENTAILED	True	jnk_cascade|p38_cascade		jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_t	MARK_AS_OVER_ANNOTATED
human/MAPK1	P28482	9606	GO:0051493	regulation of cytoskeleton organization	ARBA:ARBA00027391	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0061514	interleukin-34-mediated signaling pathway	ARBA:ARBA00093749	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0070371	ERK1 and ERK2 cascade	ARBA:ARBA00085205	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	ACCEPT
human/MAPK1	P28482	9606	GO:0070849	response to epidermal growth factor	ARBA:ARBA00086481	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0072584	caveolin-mediated endocytosis	ARBA:ARBA00028693	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:0120041	positive regulation of macrophage proliferation	ARBA:ARBA00090059	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK1	P28482	9606	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK14	Q16539	9606	GO:0032735	positive regulation of interleukin-12 production	ARBA:ARBA00085778	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAPK14	Q16539	9606	GO:0051149	positive regulation of muscle cell differentiation	ARBA:ARBA00087706	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAPK14	Q16539	9606	GO:0051403	stress-activated MAPK cascade	ARBA:ARBA00035551	ENTAILED	True	jnk_cascade|p38_cascade		jnk_cascade:jnk_map2k_activity|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|p38_cascade:p38_map2k_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|mapk_relay|met	ACCEPT
human/MAPK14	Q16539	9606	GO:0071493	cellular response to UV-B	ARBA:ARBA00092260	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAPK14	Q16539	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAPK14	Q16539	9606	GO:0098586	cellular response to virus	ARBA:ARBA00033919	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	MARK_AS_OVER_ANNOTATED
human/MAPK3	P27361	9606	GO:0007173	epidermal growth factor receptor signaling pathway	ARBA:ARBA00034174	ENTAILED	True	egfr_signaling		egfr_signaling:erk_mapk|egfr_signaling:grb2_drk_sem5_adaptor	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_togg	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0010759	positive regulation of macrophage chemotaxis	ARBA:ARBA00085235	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0032206	positive regulation of telomere maintenance	ARBA:ARBA00047239	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	MARK_AS_OVER_ANNOTATED
human/MAPK3	P27361	9606	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	MARK_AS_OVER_ANNOTATED
human/MAPK3	P27361	9606	GO:0034198	cellular response to amino acid starvation	ARBA:ARBA00090477	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0051403	stress-activated MAPK cascade	ARBA:ARBA00035551	ENTAILED	True	jnk_cascade|p38_cascade		jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_t	MARK_AS_OVER_ANNOTATED
human/MAPK3	P27361	9606	GO:0051493	regulation of cytoskeleton organization	ARBA:ARBA00027391	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0061514	interleukin-34-mediated signaling pathway	ARBA:ARBA00093749	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0070371	ERK1 and ERK2 cascade	ARBA:ARBA00085205	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	ACCEPT
human/MAPK3	P27361	9606	GO:0070849	response to epidermal growth factor	ARBA:ARBA00086481	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0072584	caveolin-mediated endocytosis	ARBA:ARBA00028693	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:0120041	positive regulation of macrophage proliferation	ARBA:ARBA00090059	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK3	P27361	9606	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
human/MAPK7	Q13164	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	er_unfolded_protein_response|jnk_cascade|nrf_oxidative_stress_response|p38_cascade		er_unfolded_protein_response:ire1_kinase|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|nrf_oxidative_stress_response:gsk3_kinase|nrf_oxidative_stress_response:pmk1_p38|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	apoptotic_execution_phase|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|mapk_relay|metaph	KEEP_AS_NON_CORE
human/MAPK7	Q13164	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|ki	KEEP_AS_NON_CORE
human/MAPK8	P45983	9606	GO:0000165	MAPK cascade	ARBA:ARBA00029221	ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade		erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transiti	ACCEPT
human/MAPK8	P45983	9606	GO:0038095	Fc-epsilon receptor signaling pathway	ARBA:ARBA00088066	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAPK8	P45983	9606	GO:0090398	cellular senescence	ARBA:ARBA00086844	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|ma	KEEP_AS_NON_CORE
human/MAT1A	Q00266	9606	GO:0051259	protein complex oligomerization	ARBA:ARBA00043446	NO_MODULE	False				bacterial_methionine_cycle|heat_shock_response|methionine_biosynthesis|methionine_cycle|nlrp3_inflammasome|sam_cycle	MODIFY
human/MBL2	P11226	9606	GO:0001867	complement activation, lectin pathway	ARBA:ARBA00091687	NO_MODULE	False				erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/MCL1	Q07820	9606	GO:0012501	programmed cell death	ARBA:ARBA00028943	ENTAILED	False	bcl2_family_momp_control|ferroptosis		bcl2_family_momp_control:bax_pore_effector|bcl2_family_momp_control:bcl2_bh3_guardian|bcl2_family_momp_control:bcl2l1_bclxl_bh3_guardian|bcl2_family_momp_control:mcl1_bh3_guardian|ferroptosis:slc3a2_xct_partner	mitochondrial_complex_iii	MODIFY
human/MCL1	Q07820	9606	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|mitochondrial_complex_iii	REMOVE
human/MCL1	Q07820	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|mitochondrial_complex_iii	MODIFY
human/MCTS1	Q9ULC4	9606	GO:0002188	translation reinitiation	ARBA:ARBA00087686	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|er_unfolded_protein_response	ACCEPT
human/MEF2C	Q06413	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|primordial_germ_cell_specification		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|primordial_germ_cell_specification:pgc_tripartite_network	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|m	ACCEPT
human/MEF2C	Q06413	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_tran	MARK_AS_OVER_ANNOTATED
human/MEFV	O15553	9606	GO:0032731	positive regulation of interleukin-1 beta production	ARBA:ARBA00033916	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/MEFV	O15553	9606	GO:0050727	regulation of inflammatory response	ARBA:ARBA00045047	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/MEFV	O15553	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/MEGF10	Q96KG7	9606	GO:0033002	muscle cell proliferation	ARBA:ARBA00093115	NO_MODULE	False				cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|notch_signaling|phagocytic_engulfment|wnt_signaling	KEEP_AS_NON_CORE
human/MEGF10	Q96KG7	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|notch_signaling|phagocytic_engulfment|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/MFN2	O95140	9606	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	ENTAILED	True	mitochondrial_dynamics		mitochondrial_dynamics:drp1_gtpase|mitochondrial_dynamics:fzo1_gtpase	chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|urease_biogenesis_urea	ACCEPT
human/MGP	P08493	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			complex_i_accessory_subunits|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	KEEP_AS_NON_CORE
human/MKKS	Q9NPJ1	9606	GO:0003006	developmental process involved in reproduction	ARBA:ARBA00026397	NOT_ENTAILED	False	primordial_germ_cell_specification			wnt_signaling	MARK_AS_OVER_ANNOTATED
human/MKKS	Q9NPJ1	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			wnt_signaling	MARK_AS_OVER_ANNOTATED
human/MKKS	Q9NPJ1	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			wnt_signaling	MARK_AS_OVER_ANNOTATED
human/MMAB	Q96EY8	9606	GO:0009235	cobalamin metabolic process	ARBA:ARBA00090606	NOT_ENTAILED	True	cobalamin_intracellular_processing			cobalamin_absorption_transport|methionine_biosynthesis|propionyl_coa_catabolism	ACCEPT
human/MOCOS	Q96EN8	9606	GO:0032324	molybdopterin cofactor biosynthetic process	ARBA:ARBA00043347	NOT_ENTAILED	False	molybdenum_cofactor_biosynthesis				KEEP_AS_NON_CORE
human/MOCS1	Q9NZB8	9606	GO:0032324	molybdopterin cofactor biosynthetic process	ARBA:ARBA00043347	ENTAILED	False	molybdenum_cofactor_biosynthesis		molybdenum_cofactor_biosynthesis:moaA_gtp_38_cyclase|molybdenum_cofactor_biosynthesis:moaC_cpmp_synthase	mitochondrial_complex_i_core	KEEP_AS_NON_CORE
human/MOCS2	O96007	9606	GO:0032324	molybdopterin cofactor biosynthetic process	ARBA:ARBA00043347	ENTAILED	False	molybdenum_cofactor_biosynthesis		molybdenum_cofactor_biosynthesis:moaDE_mpt_synthase_complex		KEEP_AS_NON_CORE
human/MSX1	P28360	9606	GO:0009887	animal organ morphogenesis	ARBA:ARBA00028067	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/MTCH2	Q9Y6C9	9606	GO:0070585	protein localization to mitochondrion	ARBA:ARBA00028355	NO_MODULE	False				cobalamin_intracellular_processing|complex_iv_assembly_factors|hedgehog_signaling|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/MTHFD1	P11586	9606	GO:0046655	folic acid metabolic process	ARBA:ARBA00091997	NO_MODULE	False				complex_i_assembly_factors|folate_one_carbon_interconversion|hydroxyproline_catabolism|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/MTHFD1L	Q6UB35	9606	GO:0015942	formate metabolic process	ARBA:ARBA00088783	NO_MODULE	False				complex_i_assembly_factors|folate_one_carbon_interconversion|heat_shock_response|hydroxyproline_catabolism|nlrp3_inflammasome	ACCEPT
human/MTHFD1L	Q6UB35	9606	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	NOT_ENTAILED	False	alginate_polymerization_export|arginine_biosynthesis|aspartate_asparagine_metabolism|aspartate_family_threonine_biosynthesis|bacterial_cysteine_biosynthesis_via_o_acetylserine			complex_i_assembly_factors|folate_one_carbon_interconversion|heat_shock_response|hydroxyproline_catabolism|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/MTHFD1L	Q6UB35	9606	GO:0046653	tetrahydrofolate metabolic process	ARBA:ARBA00033901	ENTAILED	False	folate_one_carbon_interconversion		folate_one_carbon_interconversion:bacterial_fold_nadp_methylene_methenyl_activity|folate_one_carbon_interconversion:cytosolic_c1thf_synthase_nadp_activity|folate_one_carbon_interconversion:cytosolic_mthfd1_nadp_methylene_methenyl_activity|folate_one_carbon_interconversion:mitochondrial_c1thf_synthase_nadp_activity|folate_one_carbon_interconversion:monofunctional_mtda_nadp_methylene_methenyl_activity	complex_i_assembly_factors|heat_shock_response|hydroxyproline_catabolism|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/MTHFD2	P13995	9606	GO:0046655	folic acid metabolic process	ARBA:ARBA00091997	NO_MODULE	False				complex_i_assembly_factors|folate_one_carbon_interconversion|hydroxyproline_catabolism|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/MTRR	Q9UBK8	9606	GO:0009235	cobalamin metabolic process	ARBA:ARBA00090606	ENTAILED	True	cobalamin_intracellular_processing		cobalamin_intracellular_processing:mmadhc_activity	complex_i_assembly_factors|homocysteine_metabolism|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/MTRR	Q9UBK8	9606	GO:0046655	folic acid metabolic process	ARBA:ARBA00091997	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors|homocysteine_metabolism|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/MTRR	Q9UBK8	9606	GO:0050667	homocysteine metabolic process	ARBA:ARBA00089512	ENTAILED	True	homocysteine_metabolism		homocysteine_metabolism:mtrr_activity	cobalamin_intracellular_processing|complex_i_assembly_factors|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/MTRR	Q9UBK8	9606	GO:0170033	obsolete L-amino acid metabolic process	ARBA:ARBA00044572	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors|homocysteine_metabolism|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	REMOVE
human/MVK	Q03426	9606	GO:0016125	sterol metabolic process	ARBA:ARBA00034378	NOT_ENTAILED	False	bile_acid_biosynthesis|cholesterol_synthesis_post_lanosterol|sterol_commitment_squalene_to_lanosterol			coenzyme_a_biosynthesis|heat_shock_response|mevalonate_pathway|nlrp3_inflammasome|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/MYD88	Q99836	9606	GO:0009617	response to bacterium	ARBA:ARBA00026494	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|cobalamin_intracellular_processing|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_	KEEP_AS_NON_CORE
human/MYH10	P35580	9606	GO:0031032	actomyosin structure organization	ARBA:ARBA00084739	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|early_metazoan_development|maternal_to_zygotic_transition|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|primary_cilium_life_cycle|primordial_germ_cell_specification	ACCEPT
human/MYH9	P35579	9606	GO:0032970	regulation of actin filament-based process	ARBA:ARBA00028754	NO_MODULE	False				apoptotic_execution_phase|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methylcit	KEEP_AS_NON_CORE
human/MYH9	P35579	9606	GO:0072359	circulatory system development	ARBA:ARBA00027039	NOT_ENTAILED	False	cardiac_specification_network			apoptotic_execution_phase|ciliary_transition_zone|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methylcit	KEEP_AS_NON_CORE
human/MYO5A	Q9Y4I1	9606	GO:0030048	actin filament-based movement	ARBA:ARBA00028189	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_ve	ACCEPT
human/MYO5A	Q9Y4I1	9606	GO:0051650	establishment of vesicle localization	ARBA:ARBA00033964	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|nucleokinesis|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_ve	ACCEPT
human/MYO7A	Q13402	9606	GO:0007040	lysosome organization	ARBA:ARBA00033903	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	MODIFY
human/MYO7A	Q13402	9606	GO:0007601	visual perception	ARBA:ARBA00086021	NOT_ENTAILED	True	retinoid_visual_cycle			complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	ACCEPT
human/MYO7A	Q13402	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	ACCEPT
human/MYO7A	Q13402	9606	GO:0030048	actin filament-based movement	ARBA:ARBA00028189	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	ACCEPT
human/MYO7A	Q13402	9606	GO:0048666	neuron development	ARBA:ARBA00028378	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	MARK_AS_OVER_ANNOTATED
human/MYO7A	Q13402	9606	GO:0090596	sensory organ morphogenesis	ARBA:ARBA00043576	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|nucleokinesis|phagocytic_engulfment|phenylacetate_catabolism|phosphorylase_kinase_complex|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/NADSYN1	Q6IA69	9606	GO:0034354	'de novo' NAD+ biosynthetic process from L-tryptophan	ARBA:ARBA00093758	ENTAILED	True	nad_de_novo_and_salvage_fungal		nad_de_novo_and_salvage_fungal:qns1_nad_synthetase_activity	arginine_biosynthesis|cuproptosis|de_novo_pyrimidine_synthesis|glutamate_glutamine_ammonia_hub|nad_biosynthesis_salvage|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|vitamin_b6_plp_metabolism	ACCEPT
human/NAGK	Q9UJ70	9606	GO:0006044	N-acetylglucosamine metabolic process	ARBA:ARBA00084676	NO_MODULE	False				coenzyme_a_biosynthesis|hexosamine_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/NAGLU	P54802	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			heparan_sulfate_lysosomal_degradation|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
human/NAGLU	P54802	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	ENTAILED	False	heparan_sulfate_lysosomal_degradation		heparan_sulfate_lysosomal_degradation:naglu_activity	phenylacetate_catabolism	MODIFY
human/NANP	Q8TBE9	9606	GO:0006054	N-acetylneuraminate metabolic process	ARBA:ARBA00084579	ENTAILED	False	sialic_acid_metabolism		sialic_acid_metabolism:nanp_activity	gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/NANS	Q9NR45	9606	GO:0006054	N-acetylneuraminate metabolic process	ARBA:ARBA00084579	ENTAILED	False	sialic_acid_metabolism		sialic_acid_metabolism:nans_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
human/NDUFAF5	Q5TEU4	9606	GO:0032981	mitochondrial respiratory chain complex I assembly	ARBA:ARBA00087368	NOT_ENTAILED	True	complex_i_assembly_factors|mitochondrial_complex_i_core			bacterial_methionine_cycle|methionine_cycle	ACCEPT
human/NDUFAF7	Q7L592	9606	GO:0032981	mitochondrial respiratory chain complex I assembly	ARBA:ARBA00087368	ENTAILED	True	complex_i_assembly_factors		complex_i_assembly_factors:ndufaf7_activity	bacterial_methionine_cycle|methionine_cycle	ACCEPT
human/NDUFS3	O75489	9606	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	ARBA:ARBA00084241	ENTAILED	True	mitochondrial_complex_i_core		mitochondrial_complex_i_core:ndufs1_activity|mitochondrial_complex_i_core:ndufs7_activity|mitochondrial_complex_i_core:ndufv1_activity|mitochondrial_complex_i_core:ndufv2_activity	complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|ferroptosis|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|ubiquinone_biosynthesis	ACCEPT
human/NDUFS4	O43181	9606	GO:0072593	reactive oxygen species metabolic process	ARBA:ARBA00028586	NO_MODULE	False				complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|ferroptosis|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
human/NEK7	Q8TDX7	9606	GO:0051225	spindle assembly	ARBA:ARBA00089339	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_ana	MODIFY
human/NEURL1	O76050	9606	GO:0010646	regulation of cell communication	ARBA:ARBA00026589	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/NEURL1	O76050	9606	GO:0023051	regulation of signaling	ARBA:ARBA00026307	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/NEURL1	O76050	9606	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/NF1	P21359	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|gtpase_switch|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/NFIA	Q12857	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/NID1	P14543	9606	GO:0071711	basement membrane organization	ARBA:ARBA00085295	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|gpcr_plc_calcium_pkc_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	ACCEPT
human/NLRP3	Q96P20	9606	GO:0009595	detection of biotic stimulus	ARBA:ARBA00034390	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	KEEP_AS_NON_CORE
human/NLRP3	Q96P20	9606	GO:0009615	response to virus	ARBA:ARBA00026492	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	KEEP_AS_NON_CORE
human/NLRP3	Q96P20	9606	GO:0032731	positive regulation of interleukin-1 beta production	ARBA:ARBA00033916	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	ACCEPT
human/NLRP3	Q96P20	9606	GO:0044546	NLRP3 inflammasome complex assembly	ARBA:ARBA00086550	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	ACCEPT
human/NLRP3	Q96P20	9606	GO:0050729	positive regulation of inflammatory response	ARBA:ARBA00045046	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	ACCEPT
human/NLRP3	Q96P20	9606	GO:0051260	protein homooligomerization	ARBA:ARBA00089314	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	ACCEPT
human/NLRP3	Q96P20	9606	GO:0071222	cellular response to lipopolysaccharide	ARBA:ARBA00092913	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_q10_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|li	ACCEPT
human/NME2	P22392	9606	GO:0009142	nucleoside triphosphate biosynthetic process	ARBA:ARBA00033837	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:udp_ndp_kinase_activity	apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|cuproptosis|dntp_de_novo_synthesis|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|purine_nucleotide_interconversion|sphingolipid_de_novo_synthesis|wnt_signa	ACCEPT
human/NMNAT1	Q9HAN9	9606	GO:0006163	purine nucleotide metabolic process	ARBA:ARBA00026737	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity|nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_namn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturati	MARK_AS_OVER_ANNOTATED
human/NMNAT1	Q9HAN9	9606	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity|nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_namn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturati	KEEP_AS_NON_CORE
human/NMNAT2	Q9BZQ4	9606	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity|nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_namn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	MARK_AS_OVER_ANNOTATED
human/NMNAT3	Q96T66	9606	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	mitochondrial_complex_v|nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		mitochondrial_complex_v:atpaf2_activity|nad_biosynthesis_salvage:nadd_activity|nad_biosynthesis_salvage:nmnat_namn_activity|nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_namn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	apoptotic_execution_phase|cct_chaperonin_folding|heat_shock_response|mitochondrial_complex_ii|mitochondrial_complex_iii|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/NMRK1	Q9NWW6	9606	GO:1901847	nicotinate metabolic process	ARBA:ARBA00091463	NO_MODULE	False				coenzyme_a_biosynthesis|nad_de_novo_and_salvage_fungal|nadp_synthesis_and_nr_salvage|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/NMRK2	Q9NPI5	9606	GO:1901847	nicotinate metabolic process	ARBA:ARBA00091463	NO_MODULE	False				coenzyme_a_biosynthesis|nad_de_novo_and_salvage_fungal|nadp_synthesis_and_nr_salvage|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/NOTCH1	P46531	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
human/NOTCH1	P46531	9606	GO:0046579	positive regulation of Ras protein signal transduction	ARBA:ARBA00092483	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/NOTCH1	P46531	9606	GO:0051152	positive regulation of smooth muscle cell differentiation	ARBA:ARBA00087721	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/NOTCH1	P46531	9606	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ARBA:ARBA00085202	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/NOTCH1	P46531	9606	GO:0071228	cellular response to tumor cell	ARBA:ARBA00092915	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
human/NPC1L1	Q9UHC9	9606	GO:0030301	cholesterol transport	ARBA:ARBA00034167	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			heat_shock_response|intestinal_sterol_absorption_and_efflux|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_cycle|synaptic_vesicle_exocytosis	ACCEPT
human/NPLOC4	Q8TAT6	9606	GO:0030970	retrograde protein transport, ER to cytosol	ARBA:ARBA00087984	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/NPM1	P06748	9606	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|mitophagy|nlrp3_inflammasome|notch_signaling|phagosome_maturation|retinal_determination	MARK_AS_OVER_ANNOTATED
human/NPM1	P06748	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|mitophagy|nlrp3_inflammasome|notch_signaling|phagosome_maturation|retinal_determination	KEEP_AS_NON_CORE
human/NPM1	P06748	9606	GO:0042254	ribosome biogenesis	ARBA:ARBA00026817	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|mitophagy|nlrp3_inflammasome|notch_signaling|phagosome_maturation|retinal_determination	ACCEPT
human/NPM1	P06748	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_upr|mitophagy|nlrp3_inflammasome|notch_signaling|phagosome_maturation|retinal_determination	KEEP_AS_NON_CORE
human/NRAS	P01111	9606	GO:0000165	MAPK cascade	ARBA:ARBA00029221	NOT_ENTAILED	True	erk5_cascade|jnk_cascade|mapk_relay|p38_cascade			chylomicron_assembly_secretion|complex_i_assembly_factors|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|s	ACCEPT
human/NRXN1	Q9ULB1	9606	GO:0007158	neuron cell-cell adhesion	ARBA:ARBA00085299	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MODIFY
human/NRXN1	Q9ULB1	9606	GO:0030534	adult behavior	ARBA:ARBA00086959	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN1	Q9ULB1	9606	GO:0035176	social behavior	ARBA:ARBA00091504	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN1	Q9ULB1	9606	GO:0042297	vocal learning	ARBA:ARBA00085667	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
human/NRXN1	Q9ULB1	9606	GO:0071625	vocalization behavior	ARBA:ARBA00092174	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
human/NRXN2	Q9P2S2	9606	GO:0007158	neuron cell-cell adhesion	ARBA:ARBA00085299	NO_MODULE	False				erbb2_signaling|notch_signaling	MODIFY
human/NRXN2	Q9P2S2	9606	GO:0030534	adult behavior	ARBA:ARBA00086959	NO_MODULE	False				erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN2	Q9P2S2	9606	GO:0035176	social behavior	ARBA:ARBA00091504	NO_MODULE	False				erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN2	Q9P2S2	9606	GO:0042297	vocal learning	ARBA:ARBA00085667	NO_MODULE	False				erbb2_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
human/NRXN2	Q9P2S2	9606	GO:0071625	vocalization behavior	ARBA:ARBA00092174	NO_MODULE	False				erbb2_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
human/NRXN3	Q9Y4C0	9606	GO:0007158	neuron cell-cell adhesion	ARBA:ARBA00085299	NO_MODULE	False				erbb2_signaling|notch_signaling	MODIFY
human/NRXN3	Q9Y4C0	9606	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN3	Q9Y4C0	9606	GO:0007612	learning	ARBA:ARBA00086033	NO_MODULE	False				erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN3	Q9Y4C0	9606	GO:0030534	adult behavior	ARBA:ARBA00086959	NO_MODULE	False				erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN3	Q9Y4C0	9606	GO:0035176	social behavior	ARBA:ARBA00091504	NO_MODULE	False				erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
human/NRXN3	Q9Y4C0	9606	GO:0071625	vocalization behavior	ARBA:ARBA00092174	NO_MODULE	False				erbb2_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
human/NSUN2	Q08J23	9606	GO:0006397	mRNA processing	ARBA:ARBA00028222	NO_MODULE	False				apoptotic_execution_phase|bacterial_methionine_cycle|methionine_cycle	MODIFY
human/NSUN2	Q08J23	9606	GO:0030488	tRNA methylation	ARBA:ARBA00028068	NO_MODULE	False				apoptotic_execution_phase|bacterial_methionine_cycle|methionine_cycle	ACCEPT
human/NT5C2	P49902	9606	GO:0046054	dGMP metabolic process	ARBA:ARBA00090848	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|coenzyme_a_biosynthesis|fgfr_signaling|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peptidoglycan_recycling|peroxisome-lifecycle|phenylacetate_catabo	KEEP_AS_NON_CORE
human/NTN3	O00634	9606	GO:0007409	axonogenesis	ARBA:ARBA00026520	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|kit_sign	ACCEPT
human/NUBPL	Q8TB37	9606	GO:0032981	mitochondrial respiratory chain complex I assembly	ARBA:ARBA00087368	ENTAILED	True	complex_i_assembly_factors|mitochondrial_complex_i_core		complex_i_assembly_factors:nubpl_activity|mitochondrial_complex_i_core:ndufs8_activity	cobalamin_intracellular_processing|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/NUS1	Q96E22	9606	GO:0009101	glycoprotein biosynthetic process	ARBA:ARBA00027560	ENTAILED	False	dolichyl_phosphate_biosynthesis		dolichyl_phosphate_biosynthesis:dhdds_activity|dolichyl_phosphate_biosynthesis:nus1_partner	methionine_biosynthesis	KEEP_AS_NON_CORE
human/NUS1	Q96E22	9606	GO:0032383	regulation of intracellular cholesterol transport	ARBA:ARBA00084709	NO_MODULE	False				dolichyl_phosphate_biosynthesis|methionine_biosynthesis	KEEP_AS_NON_CORE
human/OAZ1	P54368	9606	GO:0006576	biogenic amine metabolic process	ARBA:ARBA00026437	ENTAILED	False	polyamine_metabolism		polyamine_metabolism:oaz1_activity	apoptotic_execution_phase|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/ODC1	P11926	9606	GO:0006595	polyamine metabolic process	ARBA:ARBA00026605	ENTAILED	False	polyamine_metabolism		polyamine_metabolism:azin1_activity|polyamine_metabolism:odc1_activity	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
human/OPA1	O60313	9606	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	ENTAILED	True	mitochondrial_complex_iii|mitochondrial_dynamics		mitochondrial_complex_iii:uqcc3_activity|mitochondrial_dynamics:drp1_gtpase|mitochondrial_dynamics:eat3_gtpase|mitochondrial_dynamics:fzo1_gtpase	chylomicron_assembly_secretion|ciliary_transition_zone|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|nucleokinesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesi	ACCEPT
human/OPA1	O60313	9606	GO:0010821	regulation of mitochondrion organization	ARBA:ARBA00084914	NO_MODULE	False				chylomicron_assembly_secretion|ciliary_transition_zone|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_iii|mitochondrial_dynamics|nucleokinesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_co	KEEP_AS_NON_CORE
human/ORMDL3	Q8N138	9606	GO:0006665	sphingolipid metabolic process	ARBA:ARBA00028658	NOT_ENTAILED	False	glycosphingolipid_biosynthesis|glycosphingolipid_lysosomal_degradation|sphingolipid_de_novo_synthesis|sphingomyelin_cycle|sphingosine_1_phosphate_rheostat				ACCEPT
human/ORMDL3	Q8N138	9606	GO:2000303	regulation of ceramide biosynthetic process	ARBA:ARBA00027641	NO_MODULE	False					ACCEPT
human/OTUD3	Q5T2D3	9606	GO:0016579	protein deubiquitination	ARBA:ARBA00027879	NO_MODULE	False				ferroptosis|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/P2RX7	Q99572	9606	GO:0015748	organophosphate ester transport	ARBA:ARBA00028511	NOT_ENTAILED	False	mitochondrial_cofactor_carriers|mitochondrial_nucleotide_glycine_carriers|paps_sulfate_activation			bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	MARK_AS_OVER_ANNOTATED
human/P2RX7	Q99572	9606	GO:0032060	bleb assembly	ARBA:ARBA00092098	NO_MODULE	False				bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/P2RX7	Q99572	9606	GO:0032731	positive regulation of interleukin-1 beta production	ARBA:ARBA00033916	NO_MODULE	False				bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	ACCEPT
human/P2RX7	Q99572	9606	GO:0046931	pore complex assembly	ARBA:ARBA00084490	NO_MODULE	False				bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/P2RX7	Q99572	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	MODIFY
human/P2RX7	Q99572	9606	GO:0051130	positive regulation of cellular component organization	ARBA:ARBA00026675	NO_MODULE	False				bcl2_family_momp_control|erbb2_signaling|heat_shock_response|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle	MODIFY
human/P4HB	P07237	9606	GO:0034975	protein folding in endoplasmic reticulum	ARBA:ARBA00084679	NO_MODULE	False				apoptotic_execution_phase|aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|erbb2_signaling|ferroptosis|glutathione_thioredoxin_redox_systems|methylcitrate_cycle|oligosaccharyltransferase_complex|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/PAFAH1B1	P43034	9606	GO:0030900	forebrain development	ARBA:ARBA00088344	ENTAILED	False	nucleokinesis		nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle	KEEP_AS_NON_CORE
human/PAPSS1	O43252	9606	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	ARBA:ARBA00089999	ENTAILED	True	paps_sulfate_activation		paps_sulfate_activation:papss_aps_kinase|paps_sulfate_activation:papss_atp_sulfurylase	aps_dependent_assimilatory_sulfate_reduction|coenzyme_a_biosynthesis|heat_shock_response|nlrp3_inflammasome|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/PAPSS2	O95340	9606	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	ARBA:ARBA00089999	ENTAILED	True	paps_sulfate_activation		paps_sulfate_activation:papss_aps_kinase|paps_sulfate_activation:papss_atp_sulfurylase	aps_dependent_assimilatory_sulfate_reduction|coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/PARP1	P09874	9606	GO:0030592	obsolete DNA ADP-ribosylation	ARBA:ARBA00086974	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|wnt_sign	MODIFY
human/PARP1	P09874	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|insulin_receptor_signaling|methylglyoxal_detoxification			apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|wnt_sign	KEEP_AS_NON_CORE
human/PAX6	P26367	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	ENTAILED	False	cerebellum_development		cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_sign	KEEP_AS_NON_CORE
human/PAX6	P26367	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|heat_shock_response|hedgehog_signaling|kit_signal	MARK_AS_OVER_ANNOTATED
human/PAX6	P26367	9606	GO:0043010	camera-type eye development	ARBA:ARBA00084629	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/PAX6	P26367	9606	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/PAX6	P26367	9606	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	REMOVE
human/PAX7	P23759	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|kit_signaling|maternal_to_zygotic_transition|neur	KEEP_AS_NON_CORE
human/PCCB	P05166	9606	GO:0009062	fatty acid catabolic process	ARBA:ARBA00028514	NOT_ENTAILED	False	fatty_acid_beta_oxidation|methylcitrate_cycle|peroxisomal_beta_oxidation			propionyl_coa_catabolism	KEEP_AS_NON_CORE
human/PCYT1A	P49585	9606	GO:0046470	phosphatidylcholine metabolic process	ARBA:ARBA00028347	ENTAILED	False	kennedy_pathway_phospholipid_synthesis		kennedy_pathway_phospholipid_synthesis:pcyt1_activity	apoptotic_execution_phase|heat_shock_response|nlrp3_inflammasome|phosphorylase_kinase_complex|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	MODIFY
human/PCYT1B	Q9Y5K3	9606	GO:0046470	phosphatidylcholine metabolic process	ARBA:ARBA00028347	ENTAILED	False	kennedy_pathway_phospholipid_synthesis		kennedy_pathway_phospholipid_synthesis:pcyt1_activity	primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/PDGFA	P04085	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
human/PDGFB	P01127	9606	GO:0007169	cell surface receptor protein tyrosine kinase signaling pathway	ARBA:ARBA00029045	ENTAILED	False	egfr_signaling|erbb2_signaling		egfr_signaling:fly_spitz_ligand|egfr_signaling:human_egf_ligand|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand	canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis	MODIFY
human/PDGFB	P01127	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	MARK_AS_OVER_ANNOTATED
human/PDGFB	P01127	9606	GO:0010557	positive regulation of macromolecule biosynthetic process	ARBA:ARBA00027412	NOT_ENTAILED	False	maternal_to_zygotic_transition			canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	KEEP_AS_NON_CORE
human/PDGFB	P01127	9606	GO:0014911	positive regulation of smooth muscle cell migration	ARBA:ARBA00089842	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	ACCEPT
human/PDGFB	P01127	9606	GO:0048661	positive regulation of smooth muscle cell proliferation	ARBA:ARBA00091355	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	ACCEPT
human/PDGFB	P01127	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	KEEP_AS_NON_CORE
human/PDGFB	P01127	9606	GO:1902533	positive regulation of intracellular signal transduction	ARBA:ARBA00027124	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|sphingo	MARK_AS_OVER_ANNOTATED
human/PDSS2	Q86YH6	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	NOT_ENTAILED	False	adrenal_steroidogenesis|bacterial_unsaturated_fatty_acid_biosynthesis|bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation			coenzyme_q10_biosynthesis|methionine_biosynthesis|ubiquinone_biosynthesis	MARK_AS_OVER_ANNOTATED
human/PDXK	O00764	9606	GO:0042816	vitamin B6 metabolic process	ARBA:ARBA00027956	ENTAILED	True	vitamin_b6_plp_metabolism		vitamin_b6_plp_metabolism:pdxk_activity	coenzyme_a_biosynthesis|heat_shock_response|nlrp3_inflammasome|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PEA15	Q15121	9606	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	ARBA:ARBA00088654	NO_MODULE	False					ACCEPT
human/PEX12	O00623	9606	GO:0007031	peroxisome organization	ARBA:ARBA00026708	ENTAILED	True	peroxisome-lifecycle		peroxisome-lifecycle:ring_peroxin_e3_activity	alginate_o_acetylation|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_iii|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
human/PGLS	O95336	9606	GO:0009051	pentose-phosphate shunt, oxidative branch	ARBA:ARBA00028372	ENTAILED	True	pentose_phosphate_oxidative_branch		pentose_phosphate_oxidative_branch:pgls_activity	entner_doudoroff_and_gluconeogenesis|gpi_anchor_remodeling|pentose_phosphate_pathway|phenylacetate_catabolism	ACCEPT
human/PICALM	Q13492	9606	GO:0006897	endocytosis	ARBA:ARBA00027119	ENTAILED	False	ldl_receptor_mediated_endocytosis|synaptic_vesicle_endocytosis		ldl_receptor_mediated_endocytosis:apob_ldlr_binding|ldl_receptor_mediated_endocytosis:pcsk9_ldlr_binding|synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:auxilin_cochaperone|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	erbb2_signaling|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_exocytosis	ACCEPT
human/PICALM	Q13492	9606	GO:0048259	regulation of receptor-mediated endocytosis	ARBA:ARBA00089722	NO_MODULE	False				erbb2_signaling|ldl_receptor_mediated_endocytosis|necroptosis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/PIGW	Q7Z7B1	9606	GO:0006505	GPI anchor metabolic process	ARBA:ARBA00026294	ENTAILED	False	gpi_anchor_core_glycan_assembly		gpi_anchor_core_glycan_assembly:pigw_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	MARK_AS_OVER_ANNOTATED
human/PIK3C3	Q8NEB9	9606	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ARBA:ARBA00090298	ENTAILED	True	phosphoinositide_biosynthesis		phosphoinositide_biosynthesis:vps34_activity	coenzyme_a_biosynthesis|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagosome_maturation|sphingolipid_de_novo_synthesis	ACCEPT
human/PIK3CD	O00329	9606	GO:0002443	leukocyte mediated immunity	ARBA:ARBA00089210	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PIK3CD	O00329	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	kit_signaling		kit_signaling:pik3ca_pi3k_catalytic_subunit	coenzyme_a_biosynthesis|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MODIFY
human/PIK3CD	O00329	9606	GO:0010595	positive regulation of endothelial cell migration	ARBA:ARBA00092351	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PIK3CD	O00329	9606	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3CD	O00329	9606	GO:0022603	regulation of anatomical structure morphogenesis	ARBA:ARBA00026634	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3CD	O00329	9606	GO:0030155	regulation of cell adhesion	ARBA:ARBA00027437	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3CD	O00329	9606	GO:0033031	positive regulation of neutrophil apoptotic process	ARBA:ARBA00093050	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PIK3CD	O00329	9606	GO:0042113	B cell activation	ARBA:ARBA00085935	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PIK3CD	O00329	9606	GO:0051094	positive regulation of developmental process	ARBA:ARBA00027577	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3CD	O00329	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3CD	O00329	9606	GO:2000026	regulation of multicellular organismal development	ARBA:ARBA00026275	NO_MODULE	False				coenzyme_a_biosynthesis|kit_signaling|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagocytic_engulfment|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/PIK3R1	P27986	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|hedgehog_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_bio	KEEP_AS_NON_CORE
human/PIK3R1	P27986	9606	GO:0043491	phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00085897	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|hedgehog_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_bio	ACCEPT
human/PINK1	Q9BXM7	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	canonical_nlrp3_inflammasome|er_unfolded_protein_response|nlrp3_inflammasome|nrf_oxidative_stress_response		canonical_nlrp3_inflammasome:nek7_licensing|er_unfolded_protein_response:ire1_kinase|nlrp3_inflammasome:nek7_nlrp3_licensing|nrf_oxidative_stress_response:gsk3_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaph	KEEP_AS_NON_CORE
human/PINK1	Q9BXM7	9606	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling	KEEP_AS_NON_CORE
human/PINK1	Q9BXM7	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling	KEEP_AS_NON_CORE
human/PINK1	Q9BXM7	9606	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling	KEEP_AS_NON_CORE
human/PIP5K1B	O14986	9606	GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089772	NO_MODULE	False				coenzyme_a_biosynthesis|peptidoglycan_recycling|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/PLCG1	P19174	9606	GO:0019722	calcium-mediated signaling	ARBA:ARBA00027115	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cy	ACCEPT
human/PLCG1	P19174	9606	GO:0038095	Fc-epsilon receptor signaling pathway	ARBA:ARBA00088066	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cy	KEEP_AS_NON_CORE
human/PLCG1	P19174	9606	GO:0050851	antigen receptor-mediated signaling pathway	ARBA:ARBA00091706	NO_MODULE	False				egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cy	ACCEPT
human/PLCG2	P16885	9606	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			egfr_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment	KEEP_AS_NON_CORE
human/PLCG2	P16885	9606	GO:0019722	calcium-mediated signaling	ARBA:ARBA00027115	NO_MODULE	False				egfr_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment	ACCEPT
human/PLCG2	P16885	9606	GO:0038095	Fc-epsilon receptor signaling pathway	ARBA:ARBA00088066	NO_MODULE	False				egfr_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment	ACCEPT
human/PLCG2	P16885	9606	GO:0050851	antigen receptor-mediated signaling pathway	ARBA:ARBA00091706	NO_MODULE	False				egfr_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment	ACCEPT
human/PLCG2	P16885	9606	GO:1902533	positive regulation of intracellular signal transduction	ARBA:ARBA00027124	NO_MODULE	False				egfr_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kit_signaling|metazoan_autophagosome_biogenesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment	KEEP_AS_NON_CORE
human/PLK1	P53350	9606	GO:0000280	nuclear division	ARBA:ARBA00028466	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transpo	ACCEPT
human/PLK1	P53350	9606	GO:0010564	regulation of cell cycle process	ARBA:ARBA00027431	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transpo	ACCEPT
human/PMM2	O15305	9606	GO:0006013	mannose metabolic process	ARBA:ARBA00027294	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
human/PMPCA	Q10713	9606	GO:0016485	protein processing	ARBA:ARBA00028812	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	hedgehog_signaling|mitochondrial_upr|notch_signaling|phenylacetate_catabolism	ACCEPT
human/PMPCB	O75439	9606	GO:0016485	protein processing	ARBA:ARBA00028812	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	hedgehog_signaling|mitochondrial_upr|notch_signaling|phenylacetate_catabolism	ACCEPT
human/PNPLA2	Q96AD5	9606	GO:0034389	lipid droplet organization	ARBA:ARBA00029235	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|triacylglycerol_lipolysis	KEEP_AS_NON_CORE
human/PNPLA3	Q9NST1	9606	GO:0001676	long-chain fatty acid metabolic process	ARBA:ARBA00027692	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|triacylglycerol_biosynthesis|triacylglycerol_lipolysis	KEEP_AS_NON_CORE
human/PNPLA3	Q9NST1	9606	GO:0006654	phosphatidic acid biosynthetic process	ARBA:ARBA00087328	ENTAILED	True	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:agpat2_activity|triacylglycerol_biosynthesis:loa1_lpaat_activity|triacylglycerol_biosynthesis:mboat_lpaat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|triacylglycerol_lipolysis	MARK_AS_OVER_ANNOTATED
human/PNPLA3	Q9NST1	9606	GO:0019432	triglyceride biosynthetic process	ARBA:ARBA00026657	ENTAILED	True	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:agpat2_activity|triacylglycerol_biosynthesis:loa1_lpaat_activity|triacylglycerol_biosynthesis:mboat_lpaat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|triacylglycerol_lipolysis	KEEP_AS_NON_CORE
human/PPOX	P50336	9606	GO:0006785	heme B biosynthetic process	ARBA:ARBA00093713	ENTAILED	True	heme_biosynthesis		heme_biosynthesis:hemj_activity|heme_biosynthesis:hemy_activity	complex_i_assembly_factors	ACCEPT
human/PPP3CA	Q08209	9606	GO:0033173	calcineurin-NFAT signaling cascade	ARBA:ARBA00092841	NO_MODULE	False				g2_m_transition|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|phosphorylase_kinase_complex	ACCEPT
human/PPP3CB	P16298	9606	GO:0033173	calcineurin-NFAT signaling cascade	ARBA:ARBA00092841	NO_MODULE	False				g2_m_transition|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|phosphorylase_kinase_complex	ACCEPT
human/PRKN	O60260	9606	GO:0009896	positive regulation of catabolic process	ARBA:ARBA00028093	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisom	KEEP_AS_NON_CORE
human/PRKN	O60260	9606	GO:0022603	regulation of anatomical structure morphogenesis	ARBA:ARBA00026634	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisom	MARK_AS_OVER_ANNOTATED
human/PRKN	O60260	9606	GO:0050804	modulation of chemical synaptic transmission	ARBA:ARBA00029187	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisom	KEEP_AS_NON_CORE
human/PRKN	O60260	9606	GO:1903530	regulation of secretion by cell	ARBA:ARBA00027787	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisom	KEEP_AS_NON_CORE
human/PSAP	P07602	9606	GO:0010467	gene expression	ARBA:ARBA00028330	NOT_ENTAILED	False	cct_chaperonin_folding|endogenous_protein_lipoylation|gpi_anchor_core_glycan_assembly|gpi_anchor_ethanolamine_phosphate|gpi_anchor_glcnac_transferase			heat_shock_response|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	MARK_AS_OVER_ANNOTATED
human/PSEN1	P49768	9606	GO:0007220	Notch receptor processing	ARBA:ARBA00084929	NO_MODULE	False				bcl2_family_momp_control|ciliary_transition_zone|erbb2_signaling|hedgehog_signaling|mitophagy|notch_signaling|phagosome_maturation|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/PSEN2	P49810	9606	GO:0006509	membrane protein ectodomain proteolysis	ARBA:ARBA00085430	NO_MODULE	False				hedgehog_signaling|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/PSEN2	P49810	9606	GO:0007220	Notch receptor processing	ARBA:ARBA00084929	NO_MODULE	False				hedgehog_signaling|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/PSMB5	P28074	9606	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				hedgehog_signaling|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/PTEN	P60484	9606	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	MODIFY
human/PTEN	P60484	9606	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	REMOVE
human/PTEN	P60484	9606	GO:0010648	negative regulation of cell communication	ARBA:ARBA00026586	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	MODIFY
human/PTEN	P60484	9606	GO:0023057	negative regulation of signaling	ARBA:ARBA00026312	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	MODIFY
human/PTEN	P60484	9606	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	KEEP_AS_NON_CORE
human/PTEN	P60484	9606	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	KEEP_AS_NON_CORE
human/PTEN	P60484	9606	GO:0051129	negative regulation of cellular component organization	ARBA:ARBA00026626	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	MARK_AS_OVER_ANNOTATED
human/PTEN	P60484	9606	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|nlrp3_inflammasome|peptido	MARK_AS_OVER_ANNOTATED
human/PTEN	P60484	9606	GO:0051726	regulation of cell cycle	ARBA:ARBA00029144	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:cdc14_scer|metaphase_anaphase_transition_and_mitotic_exit:cdc20_coactivator|metaphase_anaphase_transition_and_mitotic_exit:cdh1_coactivator|metaphase_anaphase_transition_and_mitotic_exit:clp1_spom|metaphase_anaphase_transition_and_mitotic_exit:pp2a_b55_exit	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|nlrp3_inflammasome|peptidoglycan_recycling|phenylacetate_catabolism|prima	KEEP_AS_NON_CORE
human/PTK2	Q05397	9606	GO:0001952	regulation of cell-matrix adhesion	ARBA:ARBA00091301	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	ACCEPT
human/PTK2	Q05397	9606	GO:0007229	integrin-mediated signaling pathway	ARBA:ARBA00084939	ENTAILED	True	integrin_fak_src_signaling		integrin_fak_src_signaling:fak_kinase|integrin_fak_src_signaling:src_kinase	canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling|phagocytic_engulfment|phen	ACCEPT
human/PTK2	Q05397	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	KEEP_AS_NON_CORE
human/PTK2	Q05397	9606	GO:0008360	regulation of cell shape	ARBA:ARBA00091969	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	KEEP_AS_NON_CORE
human/PTK2	Q05397	9606	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	MARK_AS_OVER_ANNOTATED
human/PTK2	Q05397	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	KEEP_AS_NON_CORE
human/PTK2	Q05397	9606	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	MARK_AS_OVER_ANNOTATED
human/PTK2	Q05397	9606	GO:0048010	vascular endothelial growth factor receptor signaling pathway	ARBA:ARBA00043614	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	KEEP_AS_NON_CORE
human/PTK2	Q05397	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|coenzyme_a_biosynthesis|complex_i_assembly_factors|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|peptidoglycan_recycling	MARK_AS_OVER_ANNOTATED
human/PTPN11	Q06124	9606	GO:0031295	T cell costimulation	ARBA:ARBA00086532	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|g2_m_transition|gpi_anchor_remodeling|hedgehog_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	KEEP_AS_NON_CORE
human/PTPN11	Q06124	9606	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	ARBA:ARBA00091717	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|g2_m_transition|gpi_anchor_remodeling|hedgehog_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	KEEP_AS_NON_CORE
human/PTPN11	Q06124	9606	GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089771	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|g2_m_transition|gpi_anchor_remodeling|hedgehog_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	KEEP_AS_NON_CORE
human/PTPN11	Q06124	9606	GO:0060338	regulation of type I interferon-mediated signaling pathway	ARBA:ARBA00090811	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|g2_m_transition|gpi_anchor_remodeling|hedgehog_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	KEEP_AS_NON_CORE
human/PTPN11	Q06124	9606	GO:1902564	negative regulation of neutrophil activation	ARBA:ARBA00092205	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|g2_m_transition|gpi_anchor_remodeling|hedgehog_signaling|kinase_phosphatase_toggle|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autopha	KEEP_AS_NON_CORE
human/PTPN6	P29350	9606	GO:0031295	T cell costimulation	ARBA:ARBA00086532	NO_MODULE	False				cerebellum_development|egfr_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|notch_signaling|peptidoglycan_recycling|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|retinal_determination_network	ACCEPT
human/PTPN6	P29350	9606	GO:0051897	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089771	NO_MODULE	False				cerebellum_development|egfr_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|notch_signaling|peptidoglycan_recycling|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|retinal_determination_network	MARK_AS_OVER_ANNOTATED
human/PTPN6	P29350	9606	GO:0060338	regulation of type I interferon-mediated signaling pathway	ARBA:ARBA00090811	NO_MODULE	False				cerebellum_development|egfr_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|notch_signaling|peptidoglycan_recycling|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|retinal_determination_network	ACCEPT
human/PTPN6	P29350	9606	GO:1902564	negative regulation of neutrophil activation	ARBA:ARBA00092205	NO_MODULE	False				cerebellum_development|egfr_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|notch_signaling|peptidoglycan_recycling|phenylacetate_catabolism|phosphotyrosine_adaptor_recruitment|retinal_determination_network	ACCEPT
human/PYCARD	Q9ULZ3	9606	GO:0001773	myeloid dendritic cell activation	ARBA:ARBA00089633	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	ARBA:ARBA00084868	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0043124	negative regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00084264	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0050870	positive regulation of T cell activation	ARBA:ARBA00029152	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0051260	protein homooligomerization	ARBA:ARBA00089314	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	ACCEPT
human/PYCARD	Q9ULZ3	9606	GO:0051607	defense response to virus	ARBA:ARBA00026923	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	KEEP_AS_NON_CORE
human/PYCARD	Q9ULZ3	9606	GO:0140632	canonical inflammasome complex assembly	ARBA:ARBA00085691	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucle	ACCEPT
human/PYCR1	P32322	9606	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NOT_ENTAILED	True	nrf_oxidative_stress_response			arginine_catabolism_arginase_pathway|complex_i_assembly_factors|heat_shock_response|hydroxyproline_catabolism|nlrp3_inflammasome|proline_metabolism	KEEP_AS_NON_CORE
human/PYCR2	Q96C36	9606	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NOT_ENTAILED	True	nrf_oxidative_stress_response			arginine_catabolism_arginase_pathway|complex_i_assembly_factors|hydroxyproline_catabolism|proline_metabolism	KEEP_AS_NON_CORE
human/PYGL	P06737	9606	GO:0005977	glycogen metabolic process	ARBA:ARBA00028497	ENTAILED	False	glycogenolysis		glycogenolysis:phosphorylase_activity	heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/QDPR	P09417	9606	GO:0042558	pteridine-containing compound metabolic process	ARBA:ARBA00027196	ENTAILED	False	tetrahydrobiopterin_metabolism		tetrahydrobiopterin_metabolism:qdpr_activity	complex_i_assembly_factors|cuproptosis|electron_transfer_flavoprotein_system|hydroxycinnamate_vanillate_catabolism|hydroxyproline_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
human/RAB1B	Q9H0U4	9606	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ARBA:ARBA00027177	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/RAB1B	Q9H0U4	9606	GO:0007030	Golgi organization	ARBA:ARBA00091973	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/RAB1B	Q9H0U4	9606	GO:1903020	positive regulation of glycoprotein metabolic process	ARBA:ARBA00089796	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	MODIFY
human/RAB7B	Q96AH8	9606	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/RAD51B	O15315	9606	GO:0006302	double-strand break repair	ARBA:ARBA00027906	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:reca_tail_binding|bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|bacterial_ruvabc_holliday_junction_processing|cgas_sting_signaling|muth_independent_mismatch_repair	ACCEPT
human/RAD51D	O75771	9606	GO:0006302	double-strand break repair	ARBA:ARBA00027906	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:reca_tail_binding|bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair|primary_cilium_life_cycle	ACCEPT
human/RAF1	P04049	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insul	ACCEPT
human/RASA1	P20936	9606	GO:0048731	system development	ARBA:ARBA00027702	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|nucleokinesis|retinal_determination_network			apoptotic_execution_phase|canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|gtpase_switch|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagos	MODIFY
human/RASA3	Q14644	9606	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	dolichol_phosphate_sugar_donor_supply|gtpase_switch|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	REMOVE
human/RB1	P06400	9606	GO:0032502	developmental process	ARBA:ARBA00028739	ENTAILED	False	retinal_determination_network		retinal_determination_network:dach_coregulator	apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ciliary_transition_zone|ferroptosis|g1_s_transition|heat_shock_response|mitophagy|nlrp3_inflammasome|notch_signaling|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
human/RBPJ	Q06330	9606	GO:0007221	positive regulation of transcription of Notch receptor target	ARBA:ARBA00084930	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/RBPJ	Q06330	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|maternal_to_zygotic_tran	KEEP_AS_NON_CORE
human/RBX1	P62877	9606	GO:0006513	protein monoubiquitination	ARBA:ARBA00085470	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|phagosome_maturation|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/RBX1	P62877	9606	GO:0034644	cellular response to UV	ARBA:ARBA00026679	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|phagosome_maturation|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/RBX1	P62877	9606	GO:0070936	protein K48-linked ubiquitination	ARBA:ARBA00086253	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|phagosome_maturation|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/RCE1	Q9Y256	9606	GO:0080120	CAAX-box protein maturation	ARBA:ARBA00026983	NOT_ENTAILED	False	protein_prenylation_caax_processing			apoptotic_execution_phase|canonical_nlrp3_inflammasome|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|necroptosis|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|protease_activation_cascade	KEEP_AS_NON_CORE
human/RDH8	Q9NYR8	9606	GO:0006694	steroid biosynthetic process	ARBA:ARBA00028726	NOT_ENTAILED	False	adrenal_steroidogenesis|cholesterol_synthesis_post_lanosterol|sex_steroid_biosynthesis|sterol_commitment_squalene_to_lanosterol			complex_i_assembly_factors|retinoid_visual_cycle	REMOVE
human/RGS20	O76081	9606	GO:0007186	G protein-coupled receptor signaling pathway	ARBA:ARBA00029021	NOT_ENTAILED	False	gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling			canonical_nlrp3_inflammasome|chylomicron_assembly_secretion|dolichol_phosphate_sugar_donor_supply|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_l	ACCEPT
human/RIPK1	Q13546	9606	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	ENTAILED	False	nrf_oxidative_stress_response		nrf_oxidative_stress_response:gsk3_kinase|nrf_oxidative_stress_response:nsy1_map3k	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	KEEP_AS_NON_CORE
human/RIPK1	Q13546	9606	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:0060544	regulation of necroptotic process	ARBA:ARBA00090640	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:0071356	cellular response to tumor necrosis factor	ARBA:ARBA00092549	ENTAILED	False	tnf_signaling		tnf_signaling:tak1_complex_ikkbeta_kinase|tnf_signaling:tak1_map3k	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:0097191	extrinsic apoptotic signaling pathway	ARBA:ARBA00028297	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:1901026	ripoptosome assembly involved in necroptotic process	ARBA:ARBA00095321	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:2000377	regulation of reactive oxygen species metabolic process	ARBA:ARBA00086857	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	KEEP_AS_NON_CORE
human/RIPK1	Q13546	9606	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	ARBA:ARBA00087856	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK1	Q13546	9606	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ARBA:ARBA00087870	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeli	ACCEPT
human/RIPK2	O43353	9606	GO:0001819	positive regulation of cytokine production	ARBA:ARBA00028861	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_s	KEEP_AS_NON_CORE
human/RIPK2	O43353	9606	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_s	ACCEPT
human/RIPK2	O43353	9606	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway	ARBA:ARBA00085415	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_s	ACCEPT
human/RIPK2	O43353	9606	GO:0140895	cell surface toll-like receptor signaling pathway	ARBA:ARBA00087276	ENTAILED	False	tlr4_md2_lps_signaling		tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tbk1|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|erk5_cascade|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_s	KEEP_AS_NON_CORE
human/RIPK3	Q9Y572	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	MARK_AS_OVER_ANNOTATED
human/RIPK3	Q9Y572	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	cgas_sting_signaling|er_unfolded_protein_response|hippo_signaling|nfkb_canonical_signaling|nlr_signaling|nlrp3_inflammasome		cgas_sting_signaling:tbk1_kinase|er_unfolded_protein_response:ire1_kinase|hippo_signaling:lats_kinase|hippo_signaling:mst_kinase|nfkb_canonical_signaling:ikk_kinase|nfkb_canonical_signaling:tak1_complex_ikkbeta_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlrp3_inflammasome:pycard_self_oligomerization	coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autop	KEEP_AS_NON_CORE
human/RNF14	Q9UBS8	9606	GO:0060828	regulation of canonical Wnt signaling pathway	ARBA:ARBA00027468	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_upr|mitophagy|notch_signaling|peroxisome-lifecycle|retinal_determination_network|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/RNF185	Q96GF1	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/RNF185	Q96GF1	9606	GO:1904380	endoplasmic reticulum mannose trimming	ARBA:ARBA00089809	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	REMOVE
human/RNF41	Q9H4P4	9606	GO:0000209	protein polyubiquitination	ARBA:ARBA00044436	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|synaptic_vesicle_exocytosis|toll_like_re	ACCEPT
human/RNF5	Q99942	9606	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signa	ACCEPT
human/RNF5	Q99942	9606	GO:1904380	endoplasmic reticulum mannose trimming	ARBA:ARBA00089809	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|complex_i_assembly_factors|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signa	REMOVE
human/RORA	P35398	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	maternal_to_zygotic_transition		maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|kit_signaling|neural_cre	MODIFY
human/RORB	Q92753	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	maternal_to_zygotic_transition		maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|gpcr_camp_pka_signaling|	ACCEPT
human/RPE65	Q16518	9606	GO:0001523	retinoid metabolic process	ARBA:ARBA00028293	ENTAILED	False	retinoid_visual_cycle		retinoid_visual_cycle:rgr_activity|retinoid_visual_cycle:rpe65_activity	complex_i_assembly_factors|gpi_anchor_remodeling|methylcitrate_cycle|mitochondrial_complex_iii|phagocytic_engulfment|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/RPE65	Q16518	9606	GO:0120254	olefinic compound metabolic process	ARBA:ARBA00033535	ENTAILED	False	retinoid_visual_cycle		retinoid_visual_cycle:rgr_activity|retinoid_visual_cycle:rpe65_activity	complex_i_assembly_factors|gpi_anchor_remodeling|methylcitrate_cycle|mitochondrial_complex_iii|phagocytic_engulfment|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	MARK_AS_OVER_ANNOTATED
human/RPGRIP1L	Q68CZ1	9606	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				erbb2_signaling	KEEP_AS_NON_CORE
human/RRM2B	Q7LG56	9606	GO:0006281	DNA repair	ARBA:ARBA00029008	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			complex_i_assembly_factors|dntp_de_novo_synthesis|heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	ACCEPT
human/RRM2B	Q7LG56	9606	GO:0009185	ribonucleoside diphosphate metabolic process	ARBA:ARBA00044387	NOT_ENTAILED	False	emp_glycolysis|glycolysis_investment_phase|glycolysis_payoff_phase|lactate_fermentation_and_bpg_shunt			complex_i_assembly_factors|dntp_de_novo_synthesis|heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	ACCEPT
human/RRM2B	Q7LG56	9606	GO:0009265	2'-deoxyribonucleotide biosynthetic process	ARBA:ARBA00090652	ENTAILED	False	dntp_de_novo_synthesis		dntp_de_novo_synthesis:class_i_rnr_activity	complex_i_assembly_factors|heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	ACCEPT
human/RRM2B	Q7LG56	9606	GO:1901992	positive regulation of mitotic cell cycle phase transition	ARBA:ARBA00029089	NO_MODULE	False				complex_i_assembly_factors|dntp_de_novo_synthesis|heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/RUNX3	Q13761	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|kit_signaling|maternal_t	ACCEPT
human/SAMD8	Q96LT4	9606	GO:0046513	ceramide biosynthetic process	ARBA:ARBA00027419	ENTAILED	True	sphingolipid_de_novo_synthesis		sphingolipid_de_novo_synthesis:ipt1_activity	sphingomyelin_cycle	UNDECIDED
human/SAR1B	Q9Y6B6	9606	GO:0048208	COPII vesicle coat assembly	ARBA:ARBA00033956	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/SAR1B	Q9Y6B6	9606	GO:0090110	COPII-coated vesicle cargo loading	ARBA:ARBA00087216	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/SAR1B	Q9Y6B6	9606	GO:1904262	negative regulation of TORC1 signaling	ARBA:ARBA00026776	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/SAR1B	Q9Y6B6	9606	GO:1990253	cellular response to leucine starvation	ARBA:ARBA00089649	NO_MODULE	False				chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|primary_cilium_life_cycle|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis	ACCEPT
human/SAT1	P21673	9606	GO:0006595	polyamine metabolic process	ARBA:ARBA00026605	ENTAILED	False	polyamine_metabolism		polyamine_metabolism:paa1_activity|polyamine_metabolism:sat1_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/SCN1A	P35498	9606	GO:0001508	action potential	ARBA:ARBA00028325	NO_MODULE	False				bcl2_family_momp_control	ACCEPT
human/SCN9A	Q15858	9606	GO:0001508	action potential	ARBA:ARBA00028325	NO_MODULE	False				bcl2_family_momp_control	KEEP_AS_NON_CORE
human/SCO1	O75880	9606	GO:0033617	mitochondrial respiratory chain complex IV assembly	ARBA:ARBA00084552	ENTAILED	True	complex_iv_assembly_factors		complex_iv_assembly_factors:cox11_activity	cobalamin_intracellular_processing|cuproptosis|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/SCO2	O43819	9606	GO:0033617	mitochondrial respiratory chain complex IV assembly	ARBA:ARBA00084552	ENTAILED	True	complex_iv_assembly_factors		complex_iv_assembly_factors:coa6_activity|complex_iv_assembly_factors:coa7_activity|complex_iv_assembly_factors:cox11_activity	aps_dependent_assimilatory_sulfate_reduction|cobalamin_intracellular_processing|complex_i_assembly_factors|cuproptosis|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/SCP2	P22307	9606	GO:0008206	bile acid metabolic process	ARBA:ARBA00092298	NOT_ENTAILED	False	bile_acid_biosynthesis|bile_acid_synthesis_ring_modification|bile_acid_synthesis_sidechain_conjugation			alginate_o_acetylation|bacterial_l_carnitine_catabolism|erbb2_signaling|fatty_acid_beta_oxidation|intestinal_sterol_absorption_and_efflux|peroxisomal_beta_oxidation|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_cycle	KEEP_AS_NON_CORE
human/SCP2	P22307	9606	GO:0015918	sterol transport	ARBA:ARBA00026829	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			alginate_o_acetylation|bacterial_l_carnitine_catabolism|erbb2_signaling|fatty_acid_beta_oxidation|intestinal_sterol_absorption_and_efflux|peroxisomal_beta_oxidation|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_cycle	ACCEPT
human/SCP2	P22307	9606	GO:0019216	regulation of lipid metabolic process	ARBA:ARBA00028119	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|erbb2_signaling|fatty_acid_beta_oxidation|intestinal_sterol_absorption_and_efflux|peroxisomal_beta_oxidation|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_cycle	MARK_AS_OVER_ANNOTATED
human/SCP2	P22307	9606	GO:0019395	fatty acid oxidation	ARBA:ARBA00027602	ENTAILED	False	fatty_acid_beta_oxidation|peroxisomal_beta_oxidation		fatty_acid_beta_oxidation:lc_thiolase_activity|fatty_acid_beta_oxidation:med_thiolase_activity|peroxisomal_beta_oxidation:acaa1_activity|peroxisomal_beta_oxidation:scp2_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|erbb2_signaling|intestinal_sterol_absorption_and_efflux|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_cycle	KEEP_AS_NON_CORE
human/SDHAF2	Q9NX18	9606	GO:0010719	negative regulation of epithelial to mesenchymal transition	ARBA:ARBA00085215	NO_MODULE	False					KEEP_AS_NON_CORE
human/SDHAF2	Q9NX18	9606	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False					KEEP_AS_NON_CORE
human/SEC63	Q9UGP8	9606	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	ARBA:ARBA00087309	NO_MODULE	False				apoptotic_execution_phase	ACCEPT
human/SEC63	Q9UGP8	9606	GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	ARBA:ARBA00087313	NO_MODULE	False				apoptotic_execution_phase	ACCEPT
human/SECISBP2	Q96T21	9606	GO:0001514	selenocysteine incorporation	ARBA:ARBA00090133	ENTAILED	True	selenocysteine_biosynthesis_incorporation		selenocysteine_biosynthesis_incorporation:secisbp2_activity|selenocysteine_biosynthesis_incorporation:selb_secis_binding	apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	ACCEPT
human/SELENOI	Q9C0D9	9606	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	kennedy_pathway_phospholipid_synthesis|sphingolipid_de_novo_synthesis		kennedy_pathway_phospholipid_synthesis:ept_activity|sphingolipid_de_novo_synthesis:ipt1_activity		MARK_AS_OVER_ANNOTATED
human/SGPL1	O95470	9606	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	sphingosine_1_phosphate_rheostat		sphingosine_1_phosphate_rheostat:sgpl1_activity		KEEP_AS_NON_CORE
human/SGPP1	Q9BX95	9606	GO:0030149	sphingolipid catabolic process	ARBA:ARBA00085904	ENTAILED	True	sphingosine_1_phosphate_rheostat		sphingosine_1_phosphate_rheostat:sgpp_activity	gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/SGPP2	Q8IWX5	9606	GO:0030149	sphingolipid catabolic process	ARBA:ARBA00085904	ENTAILED	True	sphingosine_1_phosphate_rheostat		sphingosine_1_phosphate_rheostat:sgpp_activity	gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0007389	pattern specification process	ARBA:ARBA00027400	ENTAILED	True	body_axis_specification|hedgehog_signaling		body_axis_specification:ap_wnt_gradient|body_axis_specification:dv_bmp_gradient|body_axis_specification:lr_nodal|hedgehog_signaling:hh_autoprocessing|hedgehog_signaling:hh_cholesterol_transfer|hedgehog_signaling:mature_hh_ligand	canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_specification|protease_activation_cascade	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0007417	central nervous system development	ARBA:ARBA00026561	ENTAILED	False	cerebellum_development		cerebellum_development:purkinje_shh_signal	body_axis_specification|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_specification|protease_activ	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	MARK_AS_OVER_ANNOTATED
human/SHH	Q15465	9606	GO:0030182	neuron differentiation	ARBA:ARBA00027575	NO_MODULE	False				body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0035295	tube development	ARBA:ARBA00027800	NO_MODULE	False				body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	MARK_AS_OVER_ANNOTATED
human/SHH	Q15465	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0045165	cell fate commitment	ARBA:ARBA00043601	NOT_ENTAILED	False	cardiac_specification_network			body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	KEEP_AS_NON_CORE
human/SHH	Q15465	9606	GO:0045880	positive regulation of smoothened signaling pathway	ARBA:ARBA00086559	NO_MODULE	False				body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	ACCEPT
human/SHH	Q15465	9606	GO:0048468	cell development	ARBA:ARBA00028665	ENTAILED	False	primordial_germ_cell_specification		primordial_germ_cell_specification:pgc_inductive_signal	body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|protease_activation_cascad	MARK_AS_OVER_ANNOTATED
human/SHH	Q15465	9606	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cerebellum_development		cerebellum_development:purkinje_shh_signal	body_axis_specification|canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_specification|protease_activ	MARK_AS_OVER_ANNOTATED
human/SHH	Q15465	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				body_axis_specification|canonical_nlrp3_inflammasome|cerebellum_development|egfr_signaling|erbb2_signaling|germ_layer_specification|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|phenylacetate_catabolism|primordial_germ_cell_speci	MARK_AS_OVER_ANNOTATED
human/SHMT1	P34896	9606	GO:0006544	glycine metabolic process	ARBA:ARBA00085449	ENTAILED	False	glycine_serine_interconversion		glycine_serine_interconversion:cytosolic_shmt_activity|glycine_serine_interconversion:mitochondrial_shmt_activity|glycine_serine_interconversion:threonine_aldolase_activity	apoptotic_execution_phase|early_metazoan_development|heat_shock_response|linc_complex|maternal_to_zygotic_transition|nlrp3_inflammasome|primordial_germ_cell_specification|serine_biosynthesis_one_carbon	ACCEPT
human/SHMT1	P34896	9606	GO:0006563	L-serine metabolic process	ARBA:ARBA00044408	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	apoptotic_execution_phase|early_metazoan_development|glycine_serine_interconversion|heat_shock_response|linc_complex|maternal_to_zygotic_transition|nlrp3_inflammasome|primordial_germ_cell_specification	ACCEPT
human/SHMT1	P34896	9606	GO:0006730	one-carbon metabolic process	ARBA:ARBA00087064	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	apoptotic_execution_phase|early_metazoan_development|glycine_serine_interconversion|heat_shock_response|linc_complex|maternal_to_zygotic_transition|nlrp3_inflammasome|primordial_germ_cell_specification	ACCEPT
human/SHMT1	P34896	9606	GO:0046653	tetrahydrofolate metabolic process	ARBA:ARBA00033901	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	apoptotic_execution_phase|early_metazoan_development|glycine_serine_interconversion|heat_shock_response|linc_complex|maternal_to_zygotic_transition|nlrp3_inflammasome|primordial_germ_cell_specification	ACCEPT
human/SHMT2	P34897	9606	GO:0006544	glycine metabolic process	ARBA:ARBA00085449	ENTAILED	False	glycine_serine_interconversion		glycine_serine_interconversion:cytosolic_shmt_activity|glycine_serine_interconversion:mitochondrial_shmt_activity|glycine_serine_interconversion:threonine_aldolase_activity	heat_shock_response|nlrp3_inflammasome|serine_biosynthesis_one_carbon	ACCEPT
human/SHMT2	P34897	9606	GO:0006563	L-serine metabolic process	ARBA:ARBA00044408	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	glycine_serine_interconversion|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SHMT2	P34897	9606	GO:0006730	one-carbon metabolic process	ARBA:ARBA00087064	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	glycine_serine_interconversion|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SHMT2	P34897	9606	GO:0046653	tetrahydrofolate metabolic process	ARBA:ARBA00033901	ENTAILED	False	serine_biosynthesis_one_carbon		serine_biosynthesis_one_carbon:shmt1_activity|serine_biosynthesis_one_carbon:shmt2_activity	glycine_serine_interconversion|heat_shock_response|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/SHMT2	P34897	9606	GO:0051289	protein homotetramerization	ARBA:ARBA00089320	NO_MODULE	False				glycine_serine_interconversion|heat_shock_response|nlrp3_inflammasome|serine_biosynthesis_one_carbon	KEEP_AS_NON_CORE
human/SIAH1	Q8IUQ4	9606	GO:0060070	canonical Wnt signaling pathway	ARBA:ARBA00026624	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/SIAH1	Q8IUQ4	9606	GO:1990000	amyloid fibril formation	ARBA:ARBA00087261	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/SIAH1	Q8IUQ4	9606	GO:2001233	regulation of apoptotic signaling pathway	ARBA:ARBA00027033	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084330	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0046890	regulation of lipid biosynthetic process	ARBA:ARBA00028228	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0062013	positive regulation of small molecule metabolic process	ARBA:ARBA00089138	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT1	Q96EB6	9606	GO:0071456	cellular response to hypoxia	ARBA:ARBA00092776	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|dolichol_phosphate_sugar_donor_supply|ferroptosis|g1_s_transition|gpi_anchor_remodeling|heat_shock_response|metazoan_autophagosome_biogen	KEEP_AS_NON_CORE
human/SIRT2	Q8IXJ6	9606	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	KEEP_AS_NON_CORE
human/SIRT2	Q8IXJ6	9606	GO:0046890	regulation of lipid biosynthetic process	ARBA:ARBA00028228	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	KEEP_AS_NON_CORE
human/SIRT2	Q8IXJ6	9606	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/SIRT2	Q8IXJ6	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/SIRT2	Q8IXJ6	9606	GO:0062013	positive regulation of small molecule metabolic process	ARBA:ARBA00089138	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/SIRT2	Q8IXJ6	9606	GO:0071456	cellular response to hypoxia	ARBA:ARBA00092776	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|primary_cilium_life_cycle|wnt_signaling	KEEP_AS_NON_CORE
human/SIX3	O95343	9606	GO:0007601	visual perception	ARBA:ARBA00086021	NOT_ENTAILED	True	retinoid_visual_cycle			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	REMOVE
human/SIX6	O95475	9606	GO:0007601	visual perception	ARBA:ARBA00086021	NOT_ENTAILED	True	retinoid_visual_cycle			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|kit_signaling|maternal_t	REMOVE
human/SKP2	Q13309	9606	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	NOT_ENTAILED	True	g1_s_transition			ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_response|nucleokinesis|oligosaccharyltransferase_complex|phagocytic	ACCEPT
human/SKP2	Q13309	9606	GO:0006511	ubiquitin-dependent protein catabolic process	ARBA:ARBA00026385	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nrf_oxidative_stress_response|nucleokinesis|oligosaccharyltransferase_complex|phagocytic	ACCEPT
human/SLC22A5	O76082	9606	GO:0015837	amine transport	ARBA:ARBA00096986	NO_MODULE	False				bacterial_l_carnitine_catabolism|carnitine_shuttle	KEEP_AS_NON_CORE
human/SLC25A12	O75746	9606	GO:0043490	malate-aspartate shuttle	ARBA:ARBA00043538	ENTAILED	True	malate_aspartate_shuttle		malate_aspartate_shuttle:slc25a12_activity	gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_v|mitochondrial_dicarboxylate_tricarboxylate_carriers|nlrp3_inflammasome|synaptic_vesicle_neurotransmitter_loading|urea_cycle	ACCEPT
human/SLC25A12	O75746	9606	GO:0051592	response to calcium ion	ARBA:ARBA00088699	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|heat_shock_response|malate_aspartate_shuttle|mitochondrial_complex_v|mitochondrial_dicarboxylate_tricarboxylate_carriers|nlrp3_inflammasome|synaptic_vesicle_neurotransmitter_loading|urea_cycle	ACCEPT
human/SLC25A13	Q9UJS0	9606	GO:0043490	malate-aspartate shuttle	ARBA:ARBA00043538	ENTAILED	True	malate_aspartate_shuttle		malate_aspartate_shuttle:slc25a12_activity	gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_v|mitochondrial_dicarboxylate_tricarboxylate_carriers|nlrp3_inflammasome|synaptic_vesicle_neurotransmitter_loading|urea_cycle	ACCEPT
human/SLC25A13	Q9UJS0	9606	GO:0051592	response to calcium ion	ARBA:ARBA00088699	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|heat_shock_response|malate_aspartate_shuttle|mitochondrial_complex_v|mitochondrial_dicarboxylate_tricarboxylate_carriers|nlrp3_inflammasome|synaptic_vesicle_neurotransmitter_loading|urea_cycle	KEEP_AS_NON_CORE
human/SLC25A19	Q9HC21	9606	GO:0042723	thiamine-containing compound metabolic process	ARBA:ARBA00028583	ENTAILED	False	thiamine_uptake_and_activation		thiamine_uptake_and_activation:slc19_uptake|thiamine_uptake_and_activation:slc25a19_activity	mitochondrial_cofactor_carriers	KEEP_AS_NON_CORE
human/SLC25A36	Q96CQ1	9606	GO:0006862	nucleotide transport	ARBA:ARBA00027032	ENTAILED	False	mitochondrial_nucleotide_glycine_carriers		mitochondrial_nucleotide_glycine_carriers:slc25a36_activity		MARK_AS_OVER_ANNOTATED
human/SLC25A46	Q96AG3	9606	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	ENTAILED	False	complex_i_assembly_factors		complex_i_assembly_factors:ndufaf2_activity		KEEP_AS_NON_CORE
human/SLC27A5	Q9Y2P5	9606	GO:0006631	fatty acid metabolic process	ARBA:ARBA00028669	ENTAILED	False	peroxisomal_beta_oxidation		peroxisomal_beta_oxidation:abcd_transport_activity|peroxisomal_beta_oxidation:faa2_activity	bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation|complex_i_assembly_factors|ketone_body_oxidation	MARK_AS_OVER_ANNOTATED
human/SLC27A5	Q9Y2P5	9606	GO:0015909	long-chain fatty acid transport	ARBA:ARBA00088749	NOT_ENTAILED	False	carnitine_shuttle			bile_acid_biosynthesis|bile_acid_synthesis_sidechain_conjugation|complex_i_assembly_factors|ketone_body_oxidation|peroxisomal_beta_oxidation	KEEP_AS_NON_CORE
human/SLC35A1	P78382	9606	GO:0015748	organophosphate ester transport	ARBA:ARBA00028511	ENTAILED	False	mitochondrial_nucleotide_glycine_carriers		mitochondrial_nucleotide_glycine_carriers:slc25a36_activity	sialic_acid_metabolism	MARK_AS_OVER_ANNOTATED
human/SLC35A1	P78382	9606	GO:0015931	nucleobase-containing compound transport	ARBA:ARBA00026790	ENTAILED	False	mitochondrial_nucleotide_glycine_carriers		mitochondrial_nucleotide_glycine_carriers:slc25a36_activity	sialic_acid_metabolism	MARK_AS_OVER_ANNOTATED
human/SLC3A2	P08195	9606	GO:0015823	phenylalanine transport	ARBA:ARBA00088963	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SLC3A2	P08195	9606	GO:0015827	tryptophan transport	ARBA:ARBA00088957	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SLC40A1	Q9NP59	9606	GO:0055085	transmembrane transport	ARBA:ARBA00027679	NOT_ENTAILED	False	carnitine_shuttle|fructose_pts_uptake_and_catabolism|mitochondrial_cofactor_carriers|mitochondrial_dicarboxylate_tricarboxylate_carriers|mitochondrial_nucleotide_glycine_carriers			ferroptosis|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SLC45A4	Q5BKX6	9606	GO:0019233	sensory perception of pain	ARBA:ARBA00095233	NO_MODULE	False				mitochondrial_complex_v	ACCEPT
human/SLC7A11	Q9UPY5	9606	GO:0015813	L-glutamate transmembrane transport	ARBA:ARBA00043350	MODULE_INCOMPLETE	True	mitochondrial_dicarboxylate_tricarboxylate_carriers	mitochondrial_dicarboxylate_tricarboxylate_carriers:dicarboxylate_tricarboxylate_carriers	mitochondrial_dicarboxylate_tricarboxylate_carriers:slc25a22_activity	bcl2_family_momp_control|ferroptosis|mitochondrial_complex_v|synaptic_vesicle_neurotransmitter_loading	ACCEPT
human/SLC7A11	Q9UPY5	9606	GO:0043067	regulation of programmed cell death	ARBA:ARBA00027742	NO_MODULE	False				bcl2_family_momp_control|ferroptosis|mitochondrial_complex_v|mitochondrial_dicarboxylate_tricarboxylate_carriers|synaptic_vesicle_neurotransmitter_loading	MODIFY
human/SLX4	Q8IY92	9606	GO:0032206	positive regulation of telomere maintenance	ARBA:ARBA00047239	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/SMAD3	P84022	9606	GO:0032502	developmental process	ARBA:ARBA00028739	ENTAILED	False	body_axis_specification|cardiac_specification_network|cerebellum_development|early_metazoan_development|germ_layer_specification|hedgehog_signaling|maternal_to_zygotic_transition|neural_crest_gene_regulatory_network|neural_ectoderm_anteroposterior_specification|primordial_germ_cell_specification|retinal_determination_network		body_axis_specification:ap_anterior_readout|body_axis_specification:ap_posterior_readout|body_axis_specification:dv_organizer_tf|cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|early_metazoan_development:emd_axes_readout|early_metazoan_development:emd_germ_layer_master|early_metazoan_development:emd_mzt_zga_factor|germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt|hedgehog_signaling:ci_gli_activator|maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|neural_ectoderm_anteroposterior_specification:ane_otx2|neural_ectoderm_anteroposterior_specification:fb_foxg1|neural_ectoderm_anteroposterior_specification:fb_six3|neural_ectoderm_anteroposterior_specification:mb_en1|neural_ectoderm_anteroposterior_specification:ne_sox2|neural_ectoderm_anteroposterior_specification:pne_gbx2|neural_ectoderm_anteroposterior_specification:pne_hox_anterior|neural_ectoderm_anteroposterior_specification:r56_hnf1b|neural_ectoderm_anteroposterior_specification:r56_hoxa3|neural_ectoderm_anteroposterior_specification:r56_mafb|primordial_germ_cell_specification:pgc_tripartite_network|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|heat_shock_response|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch	MARK_AS_OVER_ANNOTATED
human/SMAD3	P84022	9606	GO:0071363	cellular response to growth factor stimulus	ARBA:ARBA00027976	NOT_ENTAILED	False	fgfr_signaling|tgfb_smad_signaling			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_l	ACCEPT
human/SMAD3	P84022	9606	GO:0141091	transforming growth factor beta receptor superfamily signaling pathway	ARBA:ARBA00043534	NOT_ENTAILED	False	tgfb_smad_signaling			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_l	ACCEPT
human/SMO	Q99835	9606	GO:0009888	tissue development	ARBA:ARBA00028065	NOT_ENTAILED	False	neural_crest_gene_regulatory_network			cerebellum_development|er_unfolded_protein_response|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|intestinal_sterol_absorption_and_efflux|metazoan_autophagosome_biogenesis|notch_signaling|primary_cilium_life_cycle|synaptic_vesicle_cycle	MARK_AS_OVER_ANNOTATED
human/SMPD1	P17405	9606	GO:0001778	plasma membrane repair	ARBA:ARBA00033547	NO_MODULE	False				glycosphingolipid_lysosomal_degradation|gpcr_plc_calcium_pkc_signaling|gpi_anchor_remodeling|phenylacetate_catabolism|sphingomyelin_cycle	KEEP_AS_NON_CORE
human/SMS	P52788	9606	GO:0006595	polyamine metabolic process	ARBA:ARBA00026605	ENTAILED	False	polyamine_metabolism		polyamine_metabolism:sms_activity|polyamine_metabolism:spe4_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
human/SOCS1	O15524	9606	GO:0032502	developmental process	ARBA:ARBA00028739	NOT_ENTAILED	False	body_axis_specification|cardiac_specification_network|cerebellum_development|early_metazoan_development|germ_layer_specification			apoptotic_execution_phase|erbb2_signaling|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/SOX9	P48436	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/SPG21	Q9NZD8	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	erbb2_signaling		erbb2_signaling:nrg1_nrg1_ligand		MARK_AS_OVER_ANNOTATED
human/SPHK1	Q9NYA1	9606	GO:0019216	regulation of lipid metabolic process	ARBA:ARBA00028119	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|phosphorylase_kinase_compl	MARK_AS_OVER_ANNOTATED
human/SPHK1	Q9NYA1	9606	GO:0046512	sphingosine biosynthetic process	ARBA:ARBA00027422	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|phosphorylase_kinase_compl	MODIFY
human/SPHK1	Q9NYA1	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|phosphorylase_kinase_compl	MARK_AS_OVER_ANNOTATED
human/SPHK1	Q9NYA1	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|phosphorylase_kinase_compl	MARK_AS_OVER_ANNOTATED
human/SPHK1	Q9NYA1	9606	GO:0071363	cellular response to growth factor stimulus	ARBA:ARBA00027976	NOT_ENTAILED	False	fgfr_signaling|tgfb_smad_signaling			alginate_o_acetylation|apoptotic_execution_phase|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|phosphorylase_kinase_compl	KEEP_AS_NON_CORE
human/SPHK2	Q9NRA0	9606	GO:0019216	regulation of lipid metabolic process	ARBA:ARBA00028119	NO_MODULE	False				cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|sphingosine_1_phosphate_rheostat|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/SPHK2	Q9NRA0	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|sphingosine_1_phosphate_rheostat|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/SPHK2	Q9NRA0	9606	GO:0046512	sphingosine biosynthetic process	ARBA:ARBA00027422	NO_MODULE	False				cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|sphingosine_1_phosphate_rheostat|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/SPHK2	Q9NRA0	9606	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				cerebellum_development|coenzyme_a_biosynthesis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling|peptidoglycan_recycling|sphingolipid_de_novo_synthesis|sphingosine_1_phosphate_rheostat|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/SPNS1	Q9H2V7	9606	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis				MODIFY
human/SPTLC2	O15270	9606	GO:0046512	sphingosine biosynthetic process	ARBA:ARBA00027422	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
human/SQSTM1	Q13501	9606	GO:0031399	regulation of protein modification process	ARBA:ARBA00028315	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitopha	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0002862	negative regulation of inflammatory response to antigenic stimulus	ARBA:ARBA00090107	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0031295	T cell costimulation	ARBA:ARBA00086532	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0034614	cellular response to reactive oxygen species	ARBA:ARBA00043492	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	ARBA:ARBA00088071	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0043114	regulation of vascular permeability	ARBA:ARBA00084394	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0045937	positive regulation of phosphate metabolic process	ARBA:ARBA00028182	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	MARK_AS_OVER_ANNOTATED
human/SRC	P12931	9606	GO:0048013	ephrin receptor signaling pathway	ARBA:ARBA00028551	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0050900	leukocyte migration	ARBA:ARBA00091273	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRC	P12931	9606	GO:0051057	positive regulation of small GTPase mediated signal transduction	ARBA:ARBA00088034	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
human/SRM	P19623	9606	GO:0006596	polyamine biosynthetic process	ARBA:ARBA00026615	ENTAILED	True	polyamine_metabolism		polyamine_metabolism:srm_activity	heat_shock_response|methionine_biosynthesis|nlrp3_inflammasome	KEEP_AS_NON_CORE
human/STAR	P49675	9606	GO:0015918	sterol transport	ARBA:ARBA00026829	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			adrenal_steroidogenesis|chylomicron_assembly_secretion|cobalamin_intracellular_processing|intestinal_sterol_absorption_and_efflux|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|synaptic_vesicle_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MODIFY
human/STAR	P49675	9606	GO:0042446	hormone biosynthetic process	ARBA:ARBA00028013	ENTAILED	False	adrenal_steroidogenesis		adrenal_steroidogenesis:star_activity	chylomicron_assembly_secretion|cobalamin_intracellular_processing|intestinal_sterol_absorption_and_efflux|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|synaptic_vesicle_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	MODIFY
human/STAR	P49675	9606	GO:0120178	steroid hormone biosynthetic process	ARBA:ARBA00027332	ENTAILED	True	adrenal_steroidogenesis		adrenal_steroidogenesis:star_activity	chylomicron_assembly_secretion|cobalamin_intracellular_processing|intestinal_sterol_absorption_and_efflux|metazoan_autophagosome_biogenesis|primary_cilium_life_cycle|synaptic_vesicle_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	ACCEPT
human/STAT1	P42224	9606	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
human/STAT1	P42224	9606	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
human/STAT1	P42224	9606	GO:0060333	type II interferon-mediated signaling pathway	ARBA:ARBA00090813	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
human/STAT1	P42224	9606	GO:0060337	type I interferon-mediated signaling pathway	ARBA:ARBA00033815	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
human/STAT2	P52630	9606	GO:0060337	type I interferon-mediated signaling pathway	ARBA:ARBA00033815	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/STAT2	P52630	9606	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	ARBA:ARBA00090810	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/STAT3	P40763	9606	GO:0001817	regulation of cytokine production	ARBA:ARBA00028860	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
human/STAT3	P40763	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
human/STAT3	P40763	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:stat5a_stat5_transcription_factor	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/STAT3	P40763	9606	GO:0045893	positive regulation of DNA-templated transcription	ARBA:ARBA00029082	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/STAT3	P40763	9606	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
human/STAT4	Q14765	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	ACCEPT
human/STAT4	Q14765	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:stat5a_stat5_transcription_factor	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|mate	ACCEPT
human/STAT5A	P42229	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:stat5a_stat5_transcription_factor	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/STAT5A	P42229	9606	GO:1903706	regulation of hemopoiesis	ARBA:ARBA00029137	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/STAT5B	P51692	9606	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:stat5a_stat5_transcription_factor	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/STAT5B	P51692	9606	GO:1903706	regulation of hemopoiesis	ARBA:ARBA00029137	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/STK3	Q13188	9606	GO:0006606	protein import into nucleus	ARBA:ARBA00028627	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraf	MARK_AS_OVER_ANNOTATED
human/STK3	Q13188	9606	GO:0006915	apoptotic process	ARBA:ARBA00027755	NOT_ENTAILED	False	apoptotic_execution_phase|bcl2_family_momp_control			canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraf	KEEP_AS_NON_CORE
human/STK3	Q13188	9606	GO:0035332	positive regulation of hippo signaling	ARBA:ARBA00091325	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraf	MODIFY
human/STK3	Q13188	9606	GO:0045926	negative regulation of growth	ARBA:ARBA00028151	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraf	KEEP_AS_NON_CORE
human/STK3	Q13188	9606	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|dolichol_phosphate_sugar_donor_supply|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraf	KEEP_AS_NON_CORE
human/STK36	Q9NRP7	9606	GO:0007017	microtubule-based process	ARBA:ARBA00026739	ENTAILED	False	intraflagellar_transport|nucleokinesis		intraflagellar_transport:dyf5_kinase|nucleokinesis:cdk5_p35_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagoso	MODIFY
human/STT3B	Q8TCJ2	9606	GO:0006487	protein N-linked glycosylation	ARBA:ARBA00085866	ENTAILED	True	oligosaccharyltransferase_complex		oligosaccharyltransferase_complex:stt3a_catalytic|oligosaccharyltransferase_complex:stt3b_catalytic		ACCEPT
human/STUB1	Q9UNE7	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	egfr_signaling|erbb2_signaling|fgfr_signaling|hedgehog_signaling|nlrp3_inflammasome|notch_signaling|phosphotyrosine_adaptor_recruitment|toll_like_receptor_signaling|wnt_signaling		egfr_signaling:grb2_drk_sem5_sos_adaptor|erbb2_signaling:nrg1_nrg1_ligand|fgfr_signaling:cbl_receptor_ubiquitination|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_tail_recruitment|nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:mib1_ligase|notch_signaling:neur_ligase|phosphotyrosine_adaptor_recruitment:adaptor_function|toll_like_receptor_signaling:traf6_ligase|wnt_signaling:btrc_ubiquitination|wnt_signaling:rnf43_znrf3_receptor_turnover	alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|ferroptosis|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|peroxi	KEEP_AS_NON_CORE
human/STUB1	Q9UNE7	9606	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|n	KEEP_AS_NON_CORE
human/STUB1	Q9UNE7	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:hsp12_6_shsp	alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nlrp3_inf	KEEP_AS_NON_CORE
human/SUFU	Q9UMX1	9606	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|er_unfolded_protein_response|ferroptosis|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|notch_signaling|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfm	ACCEPT
human/SUFU	Q9UMX1	9606	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	egfr_signaling|er_unfolded_protein_response|hedgehog_signaling|notch_signaling|phosphotyrosine_adaptor_recruitment		egfr_signaling:grb2_drk_sem5_sos_adaptor|er_unfolded_protein_response:bip_sensor_sequestration|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:hhip_antagonist|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_pka_inhibition|hedgehog_signaling:smo_tail_recruitment|hedgehog_signaling:sufu_sequestration|notch_signaling:hairless_adaptor|notch_signaling:spen_adaptor|phosphotyrosine_adaptor_recruitment:adaptor_function	ciliary_transition_zone|ferroptosis|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|pyruvate_metabolism|retinal_	MODIFY
human/SULT1A1	P50225	9606	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	NOT_ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|bacterial_cysteine_biosynthesis_via_o_acetylserine|bacterial_methionine_cycle|biotin_biosynthesis|biotin_cycle				MODIFY
human/SULT1B1	O43704	9606	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	NOT_ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|bacterial_cysteine_biosynthesis_via_o_acetylserine|bacterial_methionine_cycle|biotin_biosynthesis|biotin_cycle				MODIFY
human/SUN1	O94901	9606	GO:0090292	nuclear matrix anchoring at nuclear membrane	ARBA:ARBA00087029	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/SUN2	Q9UH99	9606	GO:0090292	nuclear matrix anchoring at nuclear membrane	ARBA:ARBA00087029	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/SUN5	Q8TC36	9606	GO:0007283	spermatogenesis	ARBA:ARBA00085131	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis|nucleokinesis|oligo	ACCEPT
human/SYN1	P17600	9606	GO:0007268	chemical synaptic transmission	ARBA:ARBA00028185	NOT_ENTAILED	False	synaptic_vesicle_exocytosis			ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/SYN1	P17600	9606	GO:0050804	modulation of chemical synaptic transmission	ARBA:ARBA00029187	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/SYN2	Q92777	9606	GO:0007268	chemical synaptic transmission	ARBA:ARBA00028185	NOT_ENTAILED	False	synaptic_vesicle_exocytosis			heat_shock_response|nlrp3_inflammasome	ACCEPT
human/SYN3	O14994	9606	GO:0007268	chemical synaptic transmission	ARBA:ARBA00028185	NOT_ENTAILED	False	synaptic_vesicle_exocytosis				ACCEPT
human/SYN3	O14994	9606	GO:0050804	modulation of chemical synaptic transmission	ARBA:ARBA00029187	NO_MODULE	False					ACCEPT
human/SYNE2	Q8WXH0	9606	GO:0007097	nuclear migration	ARBA:ARBA00026920	ENTAILED	True	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter|nucleokinesis:kash_nesprin_motor_adaptor|nucleokinesis:sun_inner_membrane_anchor|nucleokinesis:unc83_nuclear_motor_hub	ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis|oligosaccharyltrans	ACCEPT
human/SYNE2	Q8WXH0	9606	GO:0051642	centrosome localization	ARBA:ARBA00090277	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis|nucleokinesis|oligo	ACCEPT
human/SYVN1	Q86TM6	9606	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_ii|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	KEEP_AS_NON_CORE
human/SYVN1	Q86TM6	9606	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	ARBA:ARBA00089052	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_ii|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
human/TACO1	Q9BSH4	9606	GO:0070129	regulation of mitochondrial translation	ARBA:ARBA00097059	NO_MODULE	False				complex_i_assembly_factors|complex_iv_assembly_factors	ACCEPT
human/TBK1	Q9UHD2	9606	GO:0002218	activation of innate immune response	ARBA:ARBA00034386	ENTAILED	False	cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|toll_like_receptor_signaling		cgas_sting_signaling:tbk1_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:irak4_kinase|tlr4_md2_lps_signaling:tlr4_irak4|tlr4_md2_lps_signaling:tlr4_tbk1|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase	coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_e	ACCEPT
human/TBK1	Q9UHD2	9606	GO:0006952	defense response	ARBA:ARBA00026315	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/TBK1	Q9UHD2	9606	GO:0016239	positive regulation of macroautophagy	ARBA:ARBA00086948	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/TBK1	Q9UHD2	9606	GO:0032008	positive regulation of TOR signaling	ARBA:ARBA00092062	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/TBK1	Q9UHD2	9606	GO:0032728	positive regulation of interferon-beta production	ARBA:ARBA00085789	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/TBK1	Q9UHD2	9606	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	ACCEPT
human/TBK1	Q9UHD2	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_tra	KEEP_AS_NON_CORE
human/TBX20	Q9UMR3	9606	GO:0003179	heart valve morphogenesis	ARBA:ARBA00088519	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
human/TBX5	Q99593	9606	GO:0030326	embryonic limb morphogenesis	ARBA:ARBA00087370	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/TCP1	P17987	9606	GO:0032212	positive regulation of telomere maintenance via telomerase	ARBA:ARBA00047236	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|er_unfolded_protein_response|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|mitochondrial_upr|muth_independent_mismatch_repair|	KEEP_AS_NON_CORE
human/TFR2	Q9UP52	9606	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	ENTAILED	True	cobalamin_absorption_transport		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity	ferroptosis|wnt_signaling	ACCEPT
human/TFR2	Q9UP52	9606	GO:0060586	multicellular organismal-level iron ion homeostasis	ARBA:ARBA00092899	NO_MODULE	False				cobalamin_absorption_transport|ferroptosis|wnt_signaling	ACCEPT
human/TFRC	P02786	9606	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	ENTAILED	True	cobalamin_absorption_transport		cobalamin_absorption_transport:amn_activity|cobalamin_absorption_transport:cd320_activity|cobalamin_absorption_transport:cubn_activity	apoptotic_execution_phase|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|nlrp3_inflammasome|wnt_signaling	ACCEPT
human/TFRC	P02786	9606	GO:0060586	multicellular organismal-level iron ion homeostasis	ARBA:ARBA00092899	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|cobalamin_absorption_transport|complex_i_assembly_factors|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|nlrp3_inflammasome|wnt_signaling	ACCEPT
human/THBS1	P07996	9606	GO:0001937	negative regulation of endothelial cell proliferation	ARBA:ARBA00091247	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THBS1	P07996	9606	GO:0002684	positive regulation of immune system process	ARBA:ARBA00027011	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|phagocytic_engulfment|primary_ci	MARK_AS_OVER_ANNOTATED
human/THBS1	P07996	9606	GO:0010810	regulation of cell-substrate adhesion	ARBA:ARBA00084900	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THBS1	P07996	9606	GO:0030335	positive regulation of cell migration	ARBA:ARBA00028907	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THBS1	P07996	9606	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ARBA:ARBA00086893	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THBS1	P07996	9606	GO:0048514	blood vessel morphogenesis	ARBA:ARBA00091782	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THBS1	P07996	9606	GO:0050921	positive regulation of chemotaxis	ARBA:ARBA00091297	NO_MODULE	False				apoptotic_execution_phase|complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|phagocytic_en	ACCEPT
human/THG1L	Q9NWX6	9606	GO:0008033	tRNA processing	ARBA:ARBA00029020	NOT_ENTAILED	False	mitochondrial_trna_charging_and_initiator_formylation			apoptotic_execution_phase|egfr_signaling|fgfr_signaling|gtpase_switch|heat_shock_response|kit_signaling|nlrp3_inflammasome|phagocytic_engulfment|phagosome_maturation|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis	ACCEPT
human/THTPA	Q9BU02	9606	GO:0042723	thiamine-containing compound metabolic process	ARBA:ARBA00028583	ENTAILED	False	thiamine_uptake_and_activation		thiamine_uptake_and_activation:thtpa_activity	phenylacetate_catabolism	KEEP_AS_NON_CORE
human/TIAL1	Q01085	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|ciliary_transition_zone|early_metazoan_development|egfr_signaling|ferroptosis|hedgehog_signaling|maternal_to_zygotic_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesi	MODIFY
human/TICAM1	Q8IUC6	9606	GO:0007166	cell surface receptor signaling pathway	ARBA:ARBA00029053	ENTAILED	False	egfr_signaling|hedgehog_signaling|phosphotyrosine_adaptor_recruitment|tlr4_md2_lps_signaling|wnt_signaling		egfr_signaling:grb2_drk_sem5_sos_adaptor|hedgehog_signaling:cos2_cytoplasmic_scaffold|hedgehog_signaling:kif7_ciliary_scaffold|hedgehog_signaling:smo_tail_recruitment|phosphotyrosine_adaptor_recruitment:adaptor_function|tlr4_md2_lps_signaling:tlr4_myd88|tlr4_md2_lps_signaling:tlr4_tirap|tlr4_md2_lps_signaling:tlr4_tram|tlr4_md2_lps_signaling:tlr4_trif|wnt_signaling:dvl_recruitment|wnt_signaling:signalosome_assembly	canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|ferroptosis|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|p	MARK_AS_OVER_ANNOTATED
human/TICAM1	Q8IUC6	9606	GO:0032481	positive regulation of type I interferon production	ARBA:ARBA00049826	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic	ACCEPT
human/TICAM1	Q8IUC6	9606	GO:0043330	response to exogenous dsRNA	ARBA:ARBA00043583	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|nucleokinesis|oligosaccharyltransferase_complex|phagocytic	ACCEPT
human/TIMM44	O43615	9606	GO:0045184	establishment of protein localization	ARBA:ARBA00027110	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyro	MARK_AS_OVER_ANNOTATED
human/TKT	P29401	9606	GO:0019682	glyceraldehyde-3-phosphate metabolic process	ARBA:ARBA00047264	ENTAILED	False	pentose_phosphate_nonoxidative_branch		pentose_phosphate_nonoxidative_branch:tkt_activity	gpcr_plc_calcium_pkc_signaling|heat_shock_response|nlrp3_inflammasome|pentose_phosphate_pathway	KEEP_AS_NON_CORE
human/TLN1	Q9Y490	9606	GO:0007043	cell-cell junction assembly	ARBA:ARBA00092055	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|phagocytic_engulfment|primary_cilium_life_cycle|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MODIFY
human/TLR3	O15455	9606	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	ENTAILED	False	cgas_sting_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling		cgas_sting_signaling:cglr1_dsrna_sensor|nlrp3_inflammasome:pycard_self_oligomerization|tlr2_heterodimer_lipopeptide_signaling:tlr1_tlr2_receptor|tlr2_heterodimer_lipopeptide_signaling:tlr2_tlr6_receptor	apoptotic_execution_phase|heat_shock_response|necroptosis|notch_signaling|phagocytic_engulfment	KEEP_AS_NON_CORE
human/TLR3	O15455	9606	GO:0032722	positive regulation of chemokine production	ARBA:ARBA00085792	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR3	O15455	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	cgas_sting_signaling|nlrp3_inflammasome		cgas_sting_signaling:cglr1_dsrna_sensor|nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|heat_shock_response|necroptosis|notch_signaling|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR3	O15455	9606	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR3	O15455	9606	GO:0043330	response to exogenous dsRNA	ARBA:ARBA00043583	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR3	O15455	9606	GO:0046330	positive regulation of JNK cascade	ARBA:ARBA00093162	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR4	O00206	9606	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				erbb2_signaling|ferroptosis|heat_shock_response|necroptosis|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling	KEEP_AS_NON_CORE
human/TLR7	Q9NYK1	9606	GO:0006952	defense response	ARBA:ARBA00026315	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome			apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR7	Q9NYK1	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR7	Q9NYK1	9606	GO:0032728	positive regulation of interferon-beta production	ARBA:ARBA00085789	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR7	Q9NYK1	9606	GO:0032729	positive regulation of type II interferon production	ARBA:ARBA00085791	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR7	Q9NYK1	9606	GO:0032757	positive regulation of interleukin-8 production	ARBA:ARBA00085873	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR7	Q9NYK1	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR7	Q9NYK1	9606	GO:0140894	endolysosomal toll-like receptor signaling pathway	ARBA:ARBA00087274	NO_MODULE	False				apoptotic_execution_phase|cgas_sting_signaling|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR8	Q9NR97	9606	GO:0006952	defense response	ARBA:ARBA00026315	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome			apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR8	Q9NR97	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR8	Q9NR97	9606	GO:0032727	positive regulation of interferon-alpha production	ARBA:ARBA00085788	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR8	Q9NR97	9606	GO:0032728	positive regulation of interferon-beta production	ARBA:ARBA00085789	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR8	Q9NR97	9606	GO:0032729	positive regulation of type II interferon production	ARBA:ARBA00085791	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	MARK_AS_OVER_ANNOTATED
human/TLR8	Q9NR97	9606	GO:0032757	positive regulation of interleukin-8 production	ARBA:ARBA00085873	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR8	Q9NR97	9606	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR8	Q9NR97	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR8	Q9NR97	9606	GO:0140894	endolysosomal toll-like receptor signaling pathway	ARBA:ARBA00087274	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR9	Q9NR96	9606	GO:0006952	defense response	ARBA:ARBA00026315	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR9	Q9NR96	9606	GO:0006955	immune response	ARBA:ARBA00026313	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR9	Q9NR96	9606	GO:0032727	positive regulation of interferon-alpha production	ARBA:ARBA00085788	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR9	Q9NR96	9606	GO:0032729	positive regulation of type II interferon production	ARBA:ARBA00085791	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	MARK_AS_OVER_ANNOTATED
human/TLR9	Q9NR96	9606	GO:0032757	positive regulation of interleukin-8 production	ARBA:ARBA00085873	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR9	Q9NR96	9606	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TLR9	Q9NR96	9606	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	KEEP_AS_NON_CORE
human/TLR9	Q9NR96	9606	GO:0140894	endolysosomal toll-like receptor signaling pathway	ARBA:ARBA00087274	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|erbb2_signaling|heat_shock_response|necroptosis|nlrp3_inflammasome|phagocytic_engulfment|pirna_mediated_germline_silencing|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/TNFAIP3	P21580	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	nlrp3_inflammasome		nlrp3_inflammasome:pycard_self_oligomerization	alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	ACCEPT
human/TNFAIP3	P21580	9606	GO:0039532	negative regulation of cytoplasmic pattern recognition receptor signaling pathway	ARBA:ARBA00089226	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	ACCEPT
human/TNFAIP3	P21580	9606	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/TNFAIP3	P21580	9606	GO:0045732	positive regulation of protein catabolic process	ARBA:ARBA00026548	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	ACCEPT
human/TNFAIP3	P21580	9606	GO:0070536	protein K63-linked deubiquitination	ARBA:ARBA00085190	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	ACCEPT
human/TNFAIP3	P21580	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|insulin_receptor_signaling|methylglyoxal_detoxification			alginate_o_acetylation|apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|protease_activation_cascade|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF10A	O00220	9606	GO:0036462	TRAIL-activated apoptotic signaling pathway	ARBA:ARBA00089691	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|notch_signaling	ACCEPT
human/TNFRSF10A	O00220	9606	GO:0071260	cellular response to mechanical stimulus	ARBA:ARBA00092880	NO_MODULE	False				heat_shock_response|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF10B	O14763	9606	GO:0036462	TRAIL-activated apoptotic signaling pathway	ARBA:ARBA00089691	NO_MODULE	False				notch_signaling	ACCEPT
human/TNFRSF10B	O14763	9606	GO:0071260	cellular response to mechanical stimulus	ARBA:ARBA00092880	NO_MODULE	False				notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF1A	P19438	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF1A	P19438	9606	GO:0010557	positive regulation of macromolecule biosynthetic process	ARBA:ARBA00027412	NOT_ENTAILED	False	maternal_to_zygotic_transition			heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF1A	P19438	9606	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFRSF1A	P19438	9606	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NO_MODULE	False				heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
human/TNFSF10	P50591	9606	GO:0007154	cell communication	ARBA:ARBA00028945	ENTAILED	False	canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling		canonical_nlrp3_inflammasome:nek7_licensing|egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand|tgfb_smad_signaling:tgfb_ligand	heat_shock_response	MODIFY
human/TNFSF10	P50591	9606	GO:0023052	signaling	ARBA:ARBA00026303	ENTAILED	False	canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling		canonical_nlrp3_inflammasome:nek7_licensing|egfr_signaling:fly_spitz_ligand|egfr_signaling:worm_lin3_ligand|erbb2_signaling:nrg1_nrg1_ligand|neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization|notch_signaling:delta_ligand|notch_signaling:jagged_ligand|notch_signaling:nematode_dsl_ligand|tgfb_smad_signaling:tgfb_ligand	heat_shock_response	MODIFY
human/TNFSF10	P50591	9606	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	ARBA:ARBA00087870	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|heat_shock_response|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|tgfb_smad_signaling	ACCEPT
human/TNKS	O95271	9606	GO:0000209	protein polyubiquitination	ARBA:ARBA00044436	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	MODIFY
human/TNKS	O95271	9606	GO:0032212	positive regulation of telomere maintenance via telomerase	ARBA:ARBA00047236	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:0070198	protein localization to chromosome, telomeric region	ARBA:ARBA00092227	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:0070212	protein poly-ADP-ribosylation	ARBA:ARBA00092423	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:0070213	protein auto-ADP-ribosylation	ARBA:ARBA00092422	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:0090263	positive regulation of canonical Wnt signaling pathway	ARBA:ARBA00087063	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:1904355	positive regulation of telomere capping	ARBA:ARBA00089794	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	ACCEPT
human/TNKS	O95271	9606	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	ARBA:ARBA00089789	NO_MODULE	False				apoptotic_execution_phase|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/TOP2A	P11388	9606	GO:0045870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	ARBA:ARBA00086549	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|ferroptosis|heat_shock_response|metazoan_autophagosome_biogenesis|methylcitrate_cycle|nlrp3_inflammasome|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/TOP2B	Q02880	9606	GO:0045870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	ARBA:ARBA00086549	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|methylcitrate_cycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
human/TP53	P04637	9606	GO:0010212	response to ionizing radiation	ARBA:ARBA00090590	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/TP53	P04637	9606	GO:0051053	negative regulation of DNA metabolic process	ARBA:ARBA00088036	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/TP53	P04637	9606	GO:0071456	cellular response to hypoxia	ARBA:ARBA00092776	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/TP53	P04637	9606	GO:0097190	apoptotic signaling pathway	ARBA:ARBA00028296	NOT_ENTAILED	False	bcl2_family_momp_control			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/TP53	P04637	9606	GO:2001242	regulation of intrinsic apoptotic signaling pathway	ARBA:ARBA00087888	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
human/TRAF2	Q12933	9606	GO:0002700	regulation of production of molecular mediator of immune response	ARBA:ARBA00090360	NO_MODULE	False				alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitoti	ACCEPT
human/TRAF2	Q12933	9606	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitoti	KEEP_AS_NON_CORE
human/TRAF2	Q12933	9606	GO:0012501	programmed cell death	ARBA:ARBA00028943	ENTAILED	False	ferroptosis|necroptosis|nlrp3_inflammasome		ferroptosis:gpx4_cma|necroptosis:fadd_platform_adaptor|necroptosis:ticam1_rhim_adaptor|necroptosis:zbp1_rhim_adaptor|nlrp3_inflammasome:nlrp3_pyd_filament_adaptor|nlrp3_inflammasome:pycard_bipartite_adaptor|nlrp3_inflammasome:pycard_self_oligomerization	alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metaz	KEEP_AS_NON_CORE
human/TRAF2	Q12933	9606	GO:0043408	regulation of MAPK cascade	ARBA:ARBA00027210	NO_MODULE	False				alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitoti	ACCEPT
human/TRAF3	Q13114	9606	GO:0032479	regulation of type I interferon production	ARBA:ARBA00049827	NO_MODULE	False				alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagoso	MODIFY
human/TRAF6	Q9Y4K3	9606	GO:0141124	intracellular signaling cassette	ARBA:ARBA00044593	NOT_ENTAILED	False	erk5_cascade|gtpase_switch|jnk_cascade|mapk_relay|nfkb_canonical_signaling			alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagoso	KEEP_AS_NON_CORE
human/TRAF6	Q9Y4K3	9606	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	NOT_ENTAILED	False	glutathione_dependent_formaldehyde_detoxification|insulin_receptor_signaling|methylglyoxal_detoxification			alginate_o_acetylation|canonical_nlrp3_inflammasome|cell_cycle_progression|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|g1_s_transition|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagoso	KEEP_AS_NON_CORE
human/TREM2	Q9NZC2	9606	GO:0006909	phagocytosis	ARBA:ARBA00027650	ENTAILED	False	phagocytic_engulfment		phagocytic_engulfment:gas6_ps_bridge|phagocytic_engulfment:timd4_ps_receptor	canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	ACCEPT
human/TREM2	Q9NZC2	9606	GO:0035176	social behavior	ARBA:ARBA00091504	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/TREM2	Q9NZC2	9606	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/TREM2	Q9NZC2	9606	GO:0050850	positive regulation of calcium-mediated signaling	ARBA:ARBA00091707	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	ACCEPT
human/TREM2	Q9NZC2	9606	GO:0071396	cellular response to lipid	ARBA:ARBA00027803	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	ACCEPT
human/TREM2	Q9NZC2	9606	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly	ARBA:ARBA00090488	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|notch_signaling|phagocytic_engulfment|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
human/TRIM17	Q9Y577	9606	GO:0051865	protein autoubiquitination	ARBA:ARBA00089741	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|ciliary_transition_zone|egfr_signaling|ferroptosis|fgfr_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|notch_signaling|nucleokinesis|oligosaccharyltransf	ACCEPT
human/TRMT61A	Q96FX7	9606	GO:0006396	RNA processing	ARBA:ARBA00028223	NOT_ENTAILED	False	mitochondrial_trna_charging_and_initiator_formylation			bacterial_methionine_cycle|methionine_cycle	MODIFY
human/TSG101	Q99816	9606	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|heat_shock_response|nlrp3_inflammasome|notch_signaling|retinal_determination_network	MARK_AS_OVER_ANNOTATED
human/TSG101	Q99816	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	NOT_ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy			apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|heat_shock_response|nlrp3_inflammasome|notch_signaling|retinal_determination_network	MODIFY
human/TSG101	Q99816	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|heat_shock_response|nlrp3_inflammasome|notch_signaling|retinal_determination_network	ACCEPT
human/TSG101	Q99816	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|heat_shock_response|nlrp3_inflammasome|notch_signaling|retinal_determination_network	KEEP_AS_NON_CORE
human/TTC21B	Q7Z4L5	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation				MARK_AS_OVER_ANNOTATED
human/TTC21B	Q7Z4L5	9606	GO:0061512	protein localization to cilium	ARBA:ARBA00091714	NO_MODULE	False					ACCEPT
human/TTC8	Q8TAM2	9606	GO:0007600	sensory perception	ARBA:ARBA00027936	NOT_ENTAILED	False	retinoid_visual_cycle			wnt_signaling	MARK_AS_OVER_ANNOTATED
human/TTC8	Q8TAM2	9606	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			wnt_signaling	MARK_AS_OVER_ANNOTATED
human/TTK	P33981	9606	GO:0000280	nuclear division	ARBA:ARBA00028466	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:mps1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_transport|kinase_phosphatase_to	MODIFY
human/TTK	P33981	9606	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intraflagellar_transport|kinase_phosphatase_to	KEEP_AS_NON_CORE
human/TUSC3	Q13454	9606	GO:0006487	protein N-linked glycosylation	ARBA:ARBA00085866	NOT_ENTAILED	True	dolichol_phosphate_sugar_donor_supply|dolichyl_phosphate_biosynthesis|n_glycan_llo_assembly_cytoplasmic|n_glycan_llo_assembly_lumenal|oligosaccharyltransferase_complex				ACCEPT
human/TXN	P10599	9606	GO:0019725	cellular homeostasis	ARBA:ARBA00027105	ENTAILED	False	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:cytosolic_trx_activity|glutathione_thioredoxin_redox_systems:high_mr_trxr_activity|glutathione_thioredoxin_redox_systems:low_mr_trxr_activity	apoptotic_execution_phase|aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|heat_shock_response|nlrp3_inflammasome|oligosaccharyltransferase_complex	MODIFY
human/TYMP	P19971	9606	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	pyrimidine_nucleotide_catabolism		pyrimidine_nucleotide_catabolism:tymp_activity	heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/TYMP	P19971	9606	GO:0072527	pyrimidine-containing compound metabolic process	ARBA:ARBA00026859	ENTAILED	False	pyrimidine_nucleotide_catabolism		pyrimidine_nucleotide_catabolism:tymp_activity	heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome	MARK_AS_OVER_ANNOTATED
human/TYMP	P19971	9606	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			heat_shock_response|mitochondrial_dntp_supply|nlrp3_inflammasome|pyrimidine_nucleotide_catabolism	MARK_AS_OVER_ANNOTATED
human/UBE2T	Q9NPD8	9606	GO:0032446	protein modification by small protein conjugation	ARBA:ARBA00026720	ENTAILED	False	ubiquitin_transfer_relay		ubiquitin_transfer_relay:e2_activity	alginate_o_acetylation|peroxisome-lifecycle|wnt_signaling	ACCEPT
human/UCKL1	Q9NWZ5	9606	GO:0008655	pyrimidine-containing compound salvage	ARBA:ARBA00084547	NO_MODULE	False				coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
human/UCKL1	Q9NWZ5	9606	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	MODULE_INCOMPLETE	False	coenzyme_a_biosynthesis	coenzyme_a_biosynthesis:ketopantoate_hydroxymethyltransferase_step|coenzyme_a_biosynthesis:ketopantoate_reductase_step	coenzyme_a_biosynthesis:pok_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/UCKL1	Q9NWZ5	9606	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	NOT_ENTAILED	False	adp_heptose_biosynthesis|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis|dntp_de_novo_synthesis			coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
human/UFD1	Q92890	9606	GO:0030970	retrograde protein transport, ER to cytosol	ARBA:ARBA00087984	NO_MODULE	False				ferroptosis|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
human/UGGT1	Q9NYU2	9606	GO:1904380	endoplasmic reticulum mannose trimming	ARBA:ARBA00089809	NO_MODULE	False				osmoregulated_periplasmic_glucan_biosynthesis	REMOVE
human/UGT8	Q16880	9606	GO:0007399	nervous system development	ARBA:ARBA00027428	NOT_ENTAILED	False	cerebellum_development|nucleokinesis			glycosphingolipid_biosynthesis	KEEP_AS_NON_CORE
human/ULK1	O75385	9606	GO:0006914	autophagy	ARBA:ARBA00027757	ENTAILED	False	metazoan_autophagosome_biogenesis|mitophagy		metazoan_autophagosome_biogenesis:ulk_kinase|mitophagy:pink1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_to	ACCEPT
human/UMPS	P11172	9606	GO:0006222	UMP biosynthetic process	ARBA:ARBA00086365	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:omp_decarboxylase_activity|de_novo_pyrimidine_synthesis:orotate_phosphoribosyltransferase_activity	type_ii_fatty_acid_synthesis	ACCEPT
human/UNC119B	A6NIH7	9606	GO:0042953	lipoprotein transport	ARBA:ARBA00087852	NO_MODULE	False				primary_cilium_life_cycle	ACCEPT
human/UPF1	Q92900	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	pirna_mediated_germline_silencing		pirna_mediated_germline_silencing:znfx1_helicase	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cy	KEEP_AS_NON_CORE
human/UPF1	Q92900	9606	GO:1903313	positive regulation of mRNA metabolic process	ARBA:ARBA00026301	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|pirna_mediated_germlin	KEEP_AS_NON_CORE
human/UPF3A	Q9H1J1	9606	GO:0045727	positive regulation of translation	ARBA:ARBA00084181	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|early_metazoan_development|er_unfolded_protein_response|hedgehog_signaling|maternal_to_zygotic_transition|primordial_germ_cell_specification	KEEP_AS_NON_CORE
human/UPF3B	Q9BZI7	9606	GO:0045727	positive regulation of translation	ARBA:ARBA00084181	NO_MODULE	False				apoptotic_execution_phase|early_metazoan_development|maternal_to_zygotic_transition|primordial_germ_cell_specification	KEEP_AS_NON_CORE
human/UROS	P10746	9606	GO:0006785	heme B biosynthetic process	ARBA:ARBA00093713	ENTAILED	True	heme_biosynthesis		heme_biosynthesis:hemd_activity	methylcitrate_cycle	MARK_AS_OVER_ANNOTATED
human/USH1C	Q9Y6N9	9606	GO:0007605	sensory perception of sound	ARBA:ARBA00033578	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/USH1C	Q9Y6N9	9606	GO:0050885	neuromuscular process controlling balance	ARBA:ARBA00091748	NO_MODULE	False				complex_i_assembly_factors	MODIFY
human/USH1C	Q9Y6N9	9606	GO:1904106	protein localization to microvillus	ARBA:ARBA00087366	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/USH1C	Q9Y6N9	9606	GO:1904970	brush border assembly	ARBA:ARBA00089306	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
human/USH2A	O75445	9606	GO:0045494	photoreceptor cell maintenance	ARBA:ARBA00085416	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/USH2A	O75445	9606	GO:0060113	inner ear receptor cell differentiation	ARBA:ARBA00091585	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nlrp3_inflammasome	ACCEPT
human/UVRAG	Q9P2Y5	9606	GO:0006914	autophagy	ARBA:ARBA00027757	NOT_ENTAILED	False	metazoan_autophagosome_biogenesis|mitophagy			synaptic_vesicle_exocytosis	MODIFY
human/UVRAG	Q9P2Y5	9606	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	synaptic_vesicle_exocytosis		synaptic_vesicle_exocytosis:complexin_clamp		MODIFY
human/UVRAG	Q9P2Y5	9606	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	ARBA:ARBA00090298	NOT_ENTAILED	True	phosphoinositide_biosynthesis			synaptic_vesicle_exocytosis	ACCEPT
human/UVRAG	Q9P2Y5	9606	GO:0043933	protein-containing complex organization	ARBA:ARBA00026287	NOT_ENTAILED	False	chylomicron_assembly_secretion|complex_i_assembly_factors|complex_iv_assembly_factors|mitochondrial_complex_i_core|mitochondrial_complex_ii			synaptic_vesicle_exocytosis	MODIFY
human/VAPA	Q9P0L0	9606	GO:0019076	viral release from host cell	ARBA:ARBA00033551	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	UNDECIDED
human/VAPA	Q9P0L0	9606	GO:0030301	cholesterol transport	ARBA:ARBA00034167	NOT_ENTAILED	False	ldl_receptor_mediated_endocytosis			ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/VAPA	Q9P0L0	9606	GO:0044828	host-mediated suppression of viral genome replication	ARBA:ARBA00085585	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	UNDECIDED
human/VAPA	Q9P0L0	9606	GO:0044829	host-mediated activation of viral genome replication	ARBA:ARBA00085584	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	UNDECIDED
human/VAPA	Q9P0L0	9606	GO:0090114	COPII-coated vesicle budding	ARBA:ARBA00033856	NO_MODULE	False				ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|n_glycan_llo_assembly_cytoplasmic|necroptosis	ACCEPT
human/VEGFA	P15692	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization	cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|notch_signaling|primary_cilium_life_cycle|sphingolipid_de_novo_synthesis|tgf	MARK_AS_OVER_ANNOTATED
human/VEGFA	P15692	9606	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cili	ACCEPT
human/VEGFA	P15692	9606	GO:0043117	positive regulation of vascular permeability	ARBA:ARBA00084395	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cili	ACCEPT
human/VEGFA	P15692	9606	GO:0045766	positive regulation of angiogenesis	ARBA:ARBA00084376	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cili	ACCEPT
human/VEGFA	P15692	9606	GO:0048010	vascular endothelial growth factor receptor signaling pathway	ARBA:ARBA00043614	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|primary_cili	ACCEPT
human/VPS28	Q9UK41	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	NOT_ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy				MODIFY
human/VPS28	Q9UK41	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False					ACCEPT
human/VPS28	Q9UK41	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					KEEP_AS_NON_CORE
human/VPS37A	Q8NEZ2	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	NOT_ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy				MODIFY
human/VPS37A	Q8NEZ2	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False					ACCEPT
human/VPS37A	Q8NEZ2	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					KEEP_AS_NON_CORE
human/VPS37B	Q9H9H4	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	NOT_ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy				MARK_AS_OVER_ANNOTATED
human/VPS37B	Q9H9H4	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False					ACCEPT
human/VPS37B	Q9H9H4	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					KEEP_AS_NON_CORE
human/VPS37C	A5D8V6	9606	GO:0016236	macroautophagy	ARBA:ARBA00027245	NOT_ENTAILED	True	metazoan_autophagosome_biogenesis|mitophagy				MARK_AS_OVER_ANNOTATED
human/VPS37C	A5D8V6	9606	GO:0036258	multivesicular body assembly	ARBA:ARBA00027035	NO_MODULE	False					ACCEPT
human/VPS37C	A5D8V6	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False					KEEP_AS_NON_CORE
human/VPS4A	Q9UN37	9606	GO:0006997	nucleus organization	ARBA:ARBA00033484	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/VPS4A	Q9UN37	9606	GO:0007041	lysosomal transport	ARBA:ARBA00033548	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MODIFY
human/VPS4A	Q9UN37	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/VPS4A	Q9UN37	9606	GO:0010389	regulation of G2/M transition of mitotic cell cycle	ARBA:ARBA00093108	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MARK_AS_OVER_ANNOTATED
human/VPS4A	Q9UN37	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/VPS4A	Q9UN37	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
human/VPS4A	Q9UN37	9606	GO:0051261	protein depolymerization	ARBA:ARBA00028748	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MODIFY
human/VPS4A	Q9UN37	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/VPS4A	Q9UN37	9606	GO:0090611	obsolete ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00088020	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	MODIFY
human/VPS4A	Q9UN37	9606	GO:1903543	positive regulation of exosomal secretion	ARBA:ARBA00089029	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
human/VPS4B	O75351	9606	GO:0006997	nucleus organization	ARBA:ARBA00033484	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	KEEP_AS_NON_CORE
human/VPS4B	O75351	9606	GO:0007041	lysosomal transport	ARBA:ARBA00033548	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	MODIFY
human/VPS4B	O75351	9606	GO:0007080	mitotic metaphase chromosome alignment	ARBA:ARBA00033550	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	MARK_AS_OVER_ANNOTATED
human/VPS4B	O75351	9606	GO:0010389	regulation of G2/M transition of mitotic cell cycle	ARBA:ARBA00093108	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	MARK_AS_OVER_ANNOTATED
human/VPS4B	O75351	9606	GO:0039702	viral budding via host ESCRT complex	ARBA:ARBA00028526	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	KEEP_AS_NON_CORE
human/VPS4B	O75351	9606	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00033490	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	ACCEPT
human/VPS4B	O75351	9606	GO:0051261	protein depolymerization	ARBA:ARBA00028748	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	MODIFY
human/VPS4B	O75351	9606	GO:0061952	midbody abscission	ARBA:ARBA00029210	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	KEEP_AS_NON_CORE
human/VPS4B	O75351	9606	GO:0090611	obsolete ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	ARBA:ARBA00088020	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	MODIFY
human/VPS4B	O75351	9606	GO:1903543	positive regulation of exosomal secretion	ARBA:ARBA00089029	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylacetate_catabolism|primary_cilium_life_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocyto	KEEP_AS_NON_CORE
human/VTI1A	Q96AJ9	9606	GO:0016197	endosomal transport	ARBA:ARBA00028239	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/VTI1A	Q96AJ9	9606	GO:0061025	membrane fusion	ARBA:ARBA00028823	ENTAILED	False	snare_fusion_cycle		snare_fusion_cycle:snare_activity	ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/VWF	P04275	9606	GO:0030168	platelet activation	ARBA:ARBA00027406	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_	KEEP_AS_NON_CORE
human/VWF	P04275	9606	GO:0031589	cell-substrate adhesion	ARBA:ARBA00026745	NO_MODULE	False				complex_i_accessory_subunits|complex_i_assembly_factors|erbb2_signaling|heat_shock_response|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|nlrp3_inflammasome|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_	ACCEPT
human/WFS1	O76024	9606	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			cobalamin_intracellular_processing|complex_i_assembly_factors|hedgehog_signaling|phosphorylase_kinase_complex|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/WFS1	O76024	9606	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|er_unfolded_protein_response|erk5_cascade|gtpase_switch			cobalamin_intracellular_processing|complex_i_assembly_factors|hedgehog_signaling|phosphorylase_kinase_complex|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
human/WFS1	O76024	9606	GO:1902532	negative regulation of intracellular signal transduction	ARBA:ARBA00027125	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors|hedgehog_signaling|phosphorylase_kinase_complex|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|wnt_signaling	KEEP_AS_NON_CORE
human/WFS1	O76024	9606	GO:1903573	negative regulation of response to endoplasmic reticulum stress	ARBA:ARBA00089122	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors|hedgehog_signaling|phosphorylase_kinase_complex|primary_cilium_life_cycle|tlr2_heterodimer_lipopeptide_signaling|tlr4_md2_lps_signaling|wnt_signaling	ACCEPT
human/WIPF1	O43516	9606	GO:0030029	actin filament-based process	ARBA:ARBA00028229	NO_MODULE	False				apoptotic_execution_phase|cct_chaperonin_folding|ciliary_transition_zone|egfr_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|mitop	ACCEPT
human/WIPI2	Q9Y4P8	9606	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|canonical_nlrp3_inflammasome|er_unfolded_protein_response			ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	KEEP_AS_NON_CORE
human/WIPI2	Q9Y4P8	9606	GO:0034497	protein localization to phagophore assembly site	ARBA:ARBA00092844	NO_MODULE	False				ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|phagosome_maturation|phosphotyrosine_adaptor_recruitment|	ACCEPT
human/WT1	P19544	9606	GO:0000122	negative regulation of transcription by RNA polymerase II	ARBA:ARBA00029133	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/WT1	P19544	9606	GO:0072078	nephron tubule morphogenesis	ARBA:ARBA00089551	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	ACCEPT
human/WT1	P19544	9606	GO:0072359	circulatory system development	ARBA:ARBA00027039	ENTAILED	False	cardiac_specification_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signaling|m	KEEP_AS_NON_CORE
human/XBP1	P17861	9606	GO:0030968	endoplasmic reticulum unfolded protein response	ARBA:ARBA00087847	ENTAILED	True	er_unfolded_protein_response		er_unfolded_protein_response:hac1_transcription_factor	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_signaling|maternal_to_zygotic	ACCEPT
human/XBP1	P17861	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|kit_	KEEP_AS_NON_CORE
human/XIAP	P98170	9606	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	ARBA:ARBA00084867	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|sphingolipid_de_no	MARK_AS_OVER_ANNOTATED
human/XIAP	P98170	9606	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_6_shsp	alginate_o_acetylation|apoptotic_execution_phase|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|sphingolipid_de_novo_synthesis|toll_li	MARK_AS_OVER_ANNOTATED
human/XIAP	P98170	9606	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|sphingolipid_de_no	ACCEPT
human/XIAP	P98170	9606	GO:0046330	positive regulation of JNK cascade	ARBA:ARBA00093162	NO_MODULE	False				alginate_o_acetylation|apoptotic_execution_phase|cell_cycle_progression|fgfr_signaling|g1_s_transition|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nlrp3_inflammasome|notch_signaling|peroxisome-lifecycle|sphingolipid_de_no	KEEP_AS_NON_CORE
human/XRCC3	O43542	9606	GO:0006302	double-strand break repair	ARBA:ARBA00027906	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recc_scaffold_activity	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bacterial_ruvabc_holliday_junction_processing|gpi_anchor_remodeling|muth_independent_mismatch_repair|phenylacetate_catabolism	ACCEPT
human/YAP1	P46937	9606	GO:0002009	morphogenesis of an epithelium	ARBA:ARBA00027094	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/YAP1	P46937	9606	GO:0035329	hippo signaling	ARBA:ARBA00091361	NOT_ENTAILED	True	hippo_signaling			apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
human/YAP1	P46937	9606	GO:0045599	negative regulation of fat cell differentiation	ARBA:ARBA00085192	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/YAP1	P46937	9606	GO:0045669	positive regulation of osteoblast differentiation	ARBA:ARBA00084608	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/YAP1	P46937	9606	GO:0050679	positive regulation of epithelial cell proliferation	ARBA:ARBA00089519	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
human/YAP1	P46937	9606	GO:0072091	regulation of stem cell proliferation	ARBA:ARBA00089560	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|ferroptosis|g1_s_transition|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
human/YTHDF3	Q7Z739	9606	GO:0034063	cytoplasmic stress granule assembly	ARBA:ARBA00090787	NO_MODULE	False				apoptotic_execution_phase|ciliary_transition_zone|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|ferroptosis|hedgehog_signaling|maternal_to_zygotic_transition|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|nucleokinesis|ol	KEEP_AS_NON_CORE
human/ZAP70	P43403	9606	GO:0007159	leukocyte cell-cell adhesion	ARBA:ARBA00085300	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|phosphotyrosine_adaptor_recruitment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ZAP70	P43403	9606	GO:0045059	positive thymic T cell selection	ARBA:ARBA00093127	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|phosphotyrosine_adaptor_recruitment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ZAP70	P43403	9606	GO:0045582	positive regulation of T cell differentiation	ARBA:ARBA00028439	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|phosphotyrosine_adaptor_recruitment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ZAP70	P43403	9606	GO:0050900	leukocyte migration	ARBA:ARBA00091273	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|phosphotyrosine_adaptor_recruitment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
human/ZBP1	Q9H171	9606	GO:0002376	immune system process	ARBA:ARBA00027799	ENTAILED	False	cgas_sting_signaling|tlr2_heterodimer_lipopeptide_signaling		cgas_sting_signaling:cgas_dsdna_sensor|tlr2_heterodimer_lipopeptide_signaling:tlr1_tlr2_receptor|tlr2_heterodimer_lipopeptide_signaling:tlr2_tlr6_receptor	apoptotic_execution_phase|bacterial_recbcd_end_resection|necroptosis|phagocytic_engulfment|phenylacetate_catabolism	MODIFY
human/ZBP1	Q9H171	9606	GO:0051607	defense response to virus	ARBA:ARBA00026923	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|phenylacetate_catabolism|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/ZBP1	Q9H171	9606	GO:0060545	positive regulation of necroptotic process	ARBA:ARBA00090633	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|necroptosis|phagocytic_engulfment|phenylacetate_catabolism|tlr2_heterodimer_lipopeptide_signaling	ACCEPT
human/ZFYVE26	Q68DK2	9606	GO:0007040	lysosome organization	ARBA:ARBA00033903	NO_MODULE	False				heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|primary_cilium_life_cycle|synaptic_vesicle_endocytosis	ACCEPT
mouse/Acadl	P51174	10090	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	ARBA:ARBA00085069	NO_MODULE	False				complex_i_assembly_factors|fatty_acid_beta_oxidation|heat_shock_response|nlrp3_inflammasome	ACCEPT
mouse/Agtr1a	P29754	10090	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	ARBA:ARBA00026620	NO_MODULE	False				cerebellum_development|erbb2_signaling|ferroptosis|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metazoan_autophagosome_biogenesis|notch_signaling	KEEP_AS_NON_CORE
mouse/Akt1	P31750	10090	GO:1903898	negative regulation of PERK-mediated unfolded protein response	ARBA:ARBA00092204	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_s	KEEP_AS_NON_CORE
mouse/App	P12023	10090	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenes	MARK_AS_OVER_ANNOTATED
mouse/App	P12023	10090	GO:0030198	extracellular matrix organization	ARBA:ARBA00033927	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenes	KEEP_AS_NON_CORE
mouse/App	P12023	10090	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|cgas_sting_signaling|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|ldl_receptor_mediated_endocytosis|metazoan_autophagosome_biogenes	ACCEPT
mouse/Bcl2	P10417	10090	GO:0001541	ovarian follicle development	ARBA:ARBA00090163	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0002931	response to ischemia	ARBA:ARBA00089846	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	ARBA:ARBA00027191	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	ACCEPT
mouse/Bcl2	P10417	10090	GO:0008637	apoptotic mitochondrial changes	ARBA:ARBA00049830	ENTAILED	False	bcl2_family_momp_control		bcl2_family_momp_control:bax_pore_effector|bcl2_family_momp_control:bcl2_bh3_guardian|bcl2_family_momp_control:bcl2l1_bclxl_bh3_guardian|bcl2_family_momp_control:mcl1_bh3_guardian	apoptotic_execution_phase|bacterial_recbcd_end_resection|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0042542	response to hydrogen peroxide	ARBA:ARBA00027382	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0043523	regulation of neuron apoptotic process	ARBA:ARBA00085497	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	MODIFY
mouse/Bcl2	P10417	10090	GO:0051384	response to glucocorticoid	ARBA:ARBA00089100	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0071456	cellular response to hypoxia	ARBA:ARBA00092776	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	KEEP_AS_NON_CORE
mouse/Bcl2	P10417	10090	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	ARBA:ARBA00028301	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|bcl2_family_momp_control|ciliary_transition_zone|complex_i_assembly_factors|ferroptosis|heat_shock_response|mitophagy|nlrp3_inflammasome|phagosome_maturation|wnt_signaling	ACCEPT
mouse/Calm1	P0DP26	10090	GO:0000086	G2/M transition of mitotic cell cycle	ARBA:ARBA00090227	NOT_ENTAILED	True	g2_m_transition			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm1	P0DP26	10090	GO:0006897	endocytosis	ARBA:ARBA00027119	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm1	P0DP26	10090	GO:0051649	establishment of localization in cell	ARBA:ARBA00028679	NOT_ENTAILED	False	carnitine_shuttle|intraflagellar_transport|ldl_receptor_mediated_endocytosis|mitochondrial_nucleotide_glycine_carriers|nucleokinesis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm2	P0DP27	10090	GO:0000086	G2/M transition of mitotic cell cycle	ARBA:ARBA00090227	NOT_ENTAILED	True	g2_m_transition			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm2	P0DP27	10090	GO:0006897	endocytosis	ARBA:ARBA00027119	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm2	P0DP27	10090	GO:0051649	establishment of localization in cell	ARBA:ARBA00028679	NOT_ENTAILED	False	carnitine_shuttle|intraflagellar_transport|ldl_receptor_mediated_endocytosis|mitochondrial_nucleotide_glycine_carriers|nucleokinesis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm3	P0DP28	10090	GO:0000086	G2/M transition of mitotic cell cycle	ARBA:ARBA00090227	NOT_ENTAILED	True	g2_m_transition			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm3	P0DP28	10090	GO:0006897	endocytosis	ARBA:ARBA00027119	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|phagocytic_engulfment|synaptic_vesicle_endocytosis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Calm3	P0DP28	10090	GO:0051649	establishment of localization in cell	ARBA:ARBA00028679	NOT_ENTAILED	False	carnitine_shuttle|intraflagellar_transport|ldl_receptor_mediated_endocytosis|mitochondrial_nucleotide_glycine_carriers|nucleokinesis			apoptotic_execution_phase|canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Camk2a	P11798	10090	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	NOT_ENTAILED	True	g1_s_transition			cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaph	KEEP_AS_NON_CORE
mouse/Camk2a	P11798	10090	GO:0006816	calcium ion transport	ARBA:ARBA00028461	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaph	KEEP_AS_NON_CORE
mouse/Casp8	O89110	10090	GO:0001817	regulation of cytokine production	ARBA:ARBA00028860	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	KEEP_AS_NON_CORE
mouse/Casp8	O89110	10090	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:casp1_protease|canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:casp1_cytokine_precursor_cleavage|nlrp3_inflammasome:casp1_gsdmd_cleavage|nlrp3_inflammasome:nek7_nlrp3_licensing|nlrp3_inflammasome:pycard_self_oligomerization	apoptotic_execution_phase|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|phenylacetate_catabolism|protease_activation_cascade|sphingol	MARK_AS_OVER_ANNOTATED
mouse/Casp8	O89110	10090	GO:0009967	positive regulation of signal transduction	ARBA:ARBA00027202	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	MARK_AS_OVER_ANNOTATED
mouse/Casp8	O89110	10090	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	cardiac_specification_network|neural_crest_gene_regulatory_network|nucleokinesis|primordial_germ_cell_specification			apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	MARK_AS_OVER_ANNOTATED
mouse/Casp8	O89110	10090	GO:0043009	chordate embryonic development	ARBA:ARBA00027425	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	MARK_AS_OVER_ANNOTATED
mouse/Casp8	O89110	10090	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate	MARK_AS_OVER_ANNOTATED
mouse/Casp9	Q8C3Q9	10090	GO:0009411	response to UV	ARBA:ARBA00028103	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_catabolism|protease_activation_cascade	MARK_AS_OVER_ANNOTATED
mouse/Cbl	P22682	10090	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	MODIFY
mouse/Cbl	P22682	10090	GO:2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway	ARBA:ARBA00087618	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gpcr_plc_calcium_pkc_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|notch_signaling|peroxisome-lifecycle|phosphotyrosine_ada	ACCEPT
mouse/Ccne1	Q61457	10090	GO:0000723	telomere maintenance	ARBA:ARBA00027335	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Ccne1	Q61457	10090	GO:0006270	DNA replication initiation	ARBA:ARBA00033601	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	ACCEPT
mouse/Ccne1	Q61457	10090	GO:0007129	homologous chromosome pairing at meiosis	ARBA:ARBA00085323	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g1_s_transition|metazoan_autophagosome_biogenesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Cd48	P18181	10090	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
mouse/Cdc42	P60766	10090	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	NOT_ENTAILED	False	germ_layer_specification			alginate_o_acetylation|cell_cycle_progression|chylomicron_assembly_secretion|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|nlrp3_inflamm	KEEP_AS_NON_CORE
mouse/Cdc42	P60766	10090	GO:0051130	positive regulation of cellular component organization	ARBA:ARBA00026675	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|chylomicron_assembly_secretion|egfr_signaling|erbb2_signaling|fgfr_signaling|g1_s_transition|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitophagy|nlrp3_inflamm	KEEP_AS_NON_CORE
mouse/Cdk5r1	P61809	10090	GO:0021722	superior olivary nucleus maturation	ARBA:ARBA00084175	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|g2_m_transition|gpcr_plc_calcium_pkc_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp	KEEP_AS_NON_CORE
mouse/Cdk5r1	P61809	10090	GO:0021819	layer formation in cerebral cortex	ARBA:ARBA00086390	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|g2_m_transition|gpcr_plc_calcium_pkc_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp	KEEP_AS_NON_CORE
mouse/Cftr	P26361	10090	GO:0097186	amelogenesis	ARBA:ARBA00090096	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|bcl2_family_momp_control|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|methylcitrate_cycle|mitochondrial_complex_ii|muth_independent_mismatch_repair|nlrp3_inflammasome|peroxisome-lifecycle|phenylac	KEEP_AS_NON_CORE
mouse/Ctnnb1	Q02248	10090	GO:0045216	cell-cell junction organization	ARBA:ARBA00044861	NO_MODULE	False				canonical_nlrp3_inflammasome|complex_i_assembly_factors|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
mouse/Dll1	Q61483	10090	GO:0001944	vasculature development	ARBA:ARBA00091285	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0002064	epithelial cell development	ARBA:ARBA00027130	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0003002	regionalization	ARBA:ARBA00026387	NOT_ENTAILED	False	neural_ectoderm_anteroposterior_specification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0003158	endothelium development	ARBA:ARBA00088444	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0030182	neuron differentiation	ARBA:ARBA00027575	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0045165	cell fate commitment	ARBA:ARBA00043601	NOT_ENTAILED	False	cardiac_specification_network			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0045747	positive regulation of Notch signaling pathway	ARBA:ARBA00084351	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	ACCEPT
mouse/Dll1	Q61483	10090	GO:0048592	eye morphogenesis	ARBA:ARBA00043385	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Dll1	Q61483	10090	GO:0048598	embryonic morphogenesis	ARBA:ARBA00043386	NOT_ENTAILED	False	germ_layer_specification			canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0048638	regulation of developmental growth	ARBA:ARBA00091468	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0048871	multicellular organismal-level homeostasis	ARBA:ARBA00090712	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Dll1	Q61483	10090	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Dll1	Q61483	10090	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Dll1	Q61483	10090	GO:0060562	epithelial tube morphogenesis	ARBA:ARBA00090679	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll1	Q61483	10090	GO:0061326	renal tubule development	ARBA:ARBA00044406	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dll3	O88516	10090	GO:0050768	negative regulation of neurogenesis	ARBA:ARBA00089677	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling	REMOVE
mouse/Dnaja3	Q99M87	10090	GO:0002376	immune system process	ARBA:ARBA00027799	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			complex_i_assembly_factors|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dnaja3	Q99M87	10090	GO:0002682	regulation of immune system process	ARBA:ARBA00027003	NOT_ENTAILED	False	canonical_nlrp3_inflammasome|cgas_sting_signaling|nlr_signaling|nlrp3_inflammasome|tlr2_heterodimer_lipopeptide_signaling			complex_i_assembly_factors|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dnaja3	Q99M87	10090	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp	complex_i_assembly_factors|erbb2_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Dnaja3	Q99M87	10090	GO:0007528	neuromuscular junction development	ARBA:ARBA00086386	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dnaja3	Q99M87	10090	GO:0042127	regulation of cell population proliferation	ARBA:ARBA00027546	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dnaja3	Q99M87	10090	GO:0043069	negative regulation of programmed cell death	ARBA:ARBA00027748	NO_MODULE	False				complex_i_assembly_factors|erbb2_signaling|heat_shock_response|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Dnmt1	P13864	10090	GO:0006346	DNA methylation-dependent constitutive heterochromatin formation	ARBA:ARBA00086060	NO_MODULE	False				apoptotic_execution_phase|bacterial_methionine_cycle|bacterial_recbcd_end_resection|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methionine_cycle|mitophagy|necroptosis|nucleokinesis|oligosacchar	KEEP_AS_NON_CORE
mouse/Dnmt1	P13864	10090	GO:1903925	response to bisphenol A	ARBA:ARBA00092492	NO_MODULE	False				apoptotic_execution_phase|bacterial_methionine_cycle|bacterial_recbcd_end_resection|ciliary_transition_zone|egfr_signaling|ferroptosis|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|methionine_cycle|mitophagy|necroptosis|nucleokinesis|oligosacchar	KEEP_AS_NON_CORE
mouse/Drd1	Q61616	10090	GO:0001975	response to amphetamine	ARBA:ARBA00028220	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Drd1	Q61616	10090	GO:0008306	associative learning	ARBA:ARBA00091919	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Drd1	Q61616	10090	GO:0042220	response to cocaine	ARBA:ARBA00026543	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Drd1	Q61616	10090	GO:0046960	sensitization	ARBA:ARBA00084721	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Drd1	Q61616	10090	GO:0060292	long-term synaptic depression	ARBA:ARBA00091238	NO_MODULE	False				cerebellum_development|complex_i_assembly_factors|erbb2_signaling|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0008015	blood circulation	ARBA:ARBA00029044	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0030202	heparin proteoglycan metabolic process	ARBA:ARBA00085484	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Ednra	Q61614	10090	GO:0043123	positive regulation of canonical NF-kappaB signal transduction	ARBA:ARBA00026690	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Ednra	Q61614	10090	GO:0055078	sodium ion homeostasis	ARBA:ARBA00084789	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0061028	establishment of endothelial barrier	ARBA:ARBA00090320	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0070294	renal sodium ion absorption	ARBA:ARBA00091810	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0071806	protein transmembrane transport	ARBA:ARBA00028318	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Ednra	Q61614	10090	GO:0072112	podocyte differentiation	ARBA:ARBA00091519	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Ednra	Q61614	10090	GO:0097018	renal albumin absorption	ARBA:ARBA00090315	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	KEEP_AS_NON_CORE
mouse/Egf	P01132	10090	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
mouse/Egf	P01132	10090	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cerebellum_development		cerebellum_development:isthmic_fgf8_signal	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammaso	MARK_AS_OVER_ANNOTATED
mouse/Egf	P01132	10090	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cerebellum_development		cerebellum_development:isthmic_fgf8_signal	canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_adhesion|nlrp3_inflammaso	MARK_AS_OVER_ANNOTATED
mouse/Egf	P01132	10090	GO:0051049	regulation of transport	ARBA:ARBA00027251	NO_MODULE	False				canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
mouse/Egf	P01132	10090	GO:0080090	regulation of primary metabolic process	ARBA:ARBA00026284	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			canonical_nlrp3_inflammasome|cerebellum_development|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|fgfr_signaling|gpcr_plc_calcium_pkc_signaling|gtpase_switch|kit_signaling|metazoan_autophagosome_biogenesis|neural_ectoderm_anteroposterior_specification|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
mouse/Egfr	Q01279	10090	GO:0021537	telencephalon development	ARBA:ARBA00084940	NOT_ENTAILED	False	nucleokinesis			canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_sig	KEEP_AS_NON_CORE
mouse/Egfr	Q01279	10090	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ARBA:ARBA00086227	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|g2_m_transition|heat_shock_response|integrin_fak_src_signaling|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_sig	KEEP_AS_NON_CORE
mouse/Epo	P07321	10090	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	canonical_nlrp3_inflammasome|nlrp3_inflammasome		canonical_nlrp3_inflammasome:nek7_licensing|nlrp3_inflammasome:nek7_nlrp3_licensing	dolichol_phosphate_sugar_donor_supply|egfr_signaling|erbb2_signaling|metazoan_autophagosome_biogenesis|neurexin_transsynaptic_adhesion|notch_signaling|sphingolipid_de_novo_synthesis|tgfb_smad_signaling	MARK_AS_OVER_ANNOTATED
mouse/Fbxo2	Q80UW2	10090	GO:0006516	glycoprotein catabolic process	ARBA:ARBA00085471	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
mouse/Fbxo2	Q80UW2	10090	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084384	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
mouse/Fbxo2	Q80UW2	10090	GO:0036503	ERAD pathway	ARBA:ARBA00029018	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	ACCEPT
mouse/Gapdh	P16858	10090	GO:0006094	gluconeogenesis	ARBA:ARBA00084701	MODULE_INCOMPLETE	True	entner_doudoroff_and_gluconeogenesis	entner_doudoroff_and_gluconeogenesis:entner_doudoroff_branch	entner_doudoroff_and_gluconeogenesis:gapdh_activity	apoptotic_execution_phase|ciliary_transition_zone|complex_i_assembly_factors|emp_glycolysis|glycolysis_payoff_phase|heat_shock_response|nlrp3_inflammasome|nucleokinesis|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
mouse/Gas6	Q61592	10090	GO:0016477	cell migration	ARBA:ARBA00028795	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
mouse/Gas6	Q61592	10090	GO:0030154	cell differentiation	ARBA:ARBA00027429	ENTAILED	False	nucleokinesis		nucleokinesis:cenpf_nuclear_pore_nude_recruiter	apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	KEEP_AS_NON_CORE
mouse/Gas6	Q61592	10090	GO:0031669	cellular response to nutrient levels	ARBA:ARBA00034580	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
mouse/Gas6	Q61592	10090	GO:0050878	regulation of body fluid levels	ARBA:ARBA00029145	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|ciliary_transition_zone|egfr_signaling|erbb2_signaling|ferroptosis|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|necroptosis|neurexin_transsynaptic_ad	MARK_AS_OVER_ANNOTATED
mouse/Ghr	P16882	10090	GO:0060396	growth hormone receptor signaling pathway	ARBA:ARBA00043314	NO_MODULE	False				canonical_nlrp3_inflammasome|dolichol_phosphate_sugar_donor_supply|heat_shock_response|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|notch_signaling|sphingolipid_de_novo_synthesis	ACCEPT
mouse/Grb2	Q60631	10090	GO:0007265	Ras protein signal transduction	ARBA:ARBA00044394	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitopha	ACCEPT
mouse/Grb2	Q60631	10090	GO:0048009	insulin-like growth factor receptor signaling pathway	ARBA:ARBA00090282	NO_MODULE	False				canonical_nlrp3_inflammasome|cgas_sting_signaling|ciliary_transition_zone|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|fgfr_signaling|heat_shock_response|hedgehog_signaling|kit_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitopha	KEEP_AS_NON_CORE
mouse/Hdac1	O09106	10090	GO:0030178	negative regulation of Wnt signaling pathway	ARBA:ARBA00027587	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|g1_s_transition|gpi_anchor_remodeling|notch_signaling|phenylacetate_catabolism|retinal_determination_network|wnt_signaling	MODIFY
mouse/Hdac1	O09106	10090	GO:0060789	hair follicle placode formation	ARBA:ARBA00092744	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|g1_s_transition|gpi_anchor_remodeling|notch_signaling|phenylacetate_catabolism|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
mouse/Hdac1	O09106	10090	GO:0061029	eyelid development in camera-type eye	ARBA:ARBA00090318	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|g1_s_transition|gpi_anchor_remodeling|notch_signaling|phenylacetate_catabolism|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
mouse/Hdac1	O09106	10090	GO:0061198	fungiform papilla formation	ARBA:ARBA00090033	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|g1_s_transition|gpi_anchor_remodeling|notch_signaling|phenylacetate_catabolism|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
mouse/Hdac1	O09106	10090	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	ARBA:ARBA00087892	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|complex_i_assembly_factors|ferroptosis|g1_s_transition|gpi_anchor_remodeling|notch_signaling|phenylacetate_catabolism|retinal_determination_network|wnt_signaling	ACCEPT
mouse/Hsp90aa1	P07901	10090	GO:0032880	regulation of protein localization	ARBA:ARBA00026609	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling	KEEP_AS_NON_CORE
mouse/Hspa8	P63017	10090	GO:0006457	protein folding	ARBA:ARBA00027200	ENTAILED	True	cct_chaperonin_folding		cct_chaperonin_folding:prefoldin_complex_chaperone	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mi	ACCEPT
mouse/Jak1	P52332	10090	GO:0019221	cytokine-mediated signaling pathway	ARBA:ARBA00028236	ENTAILED	False	kit_signaling		kit_signaling:lyn_src_family_kinase	coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Jak1	P52332	10090	GO:0098761	cellular response to interleukin-7	ARBA:ARBA00091517	NO_MODULE	False				coenzyme_a_biosynthesis|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0030278	regulation of ossification	ARBA:ARBA00085650	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	MARK_AS_OVER_ANNOTATED
mouse/Mapk1	P63085	10090	GO:0042473	outer ear morphogenesis	ARBA:ARBA00087231	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0043330	response to exogenous dsRNA	ARBA:ARBA00043583	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0051493	regulation of cytoskeleton organization	ARBA:ARBA00027391	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0060020	Bergmann glial cell differentiation	ARBA:ARBA00089456	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0061308	cardiac neural crest cell development involved in heart development	ARBA:ARBA00089518	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0071356	cellular response to tumor necrosis factor	ARBA:ARBA00092549	ENTAILED	False	tnf_signaling		tnf_signaling:tak1_complex_ikkbeta_kinase	apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0072584	caveolin-mediated endocytosis	ARBA:ARBA00028693	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:0150078	positive regulation of neuroinflammatory response	ARBA:ARBA00085428	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk1	P63085	10090	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	MARK_AS_OVER_ANNOTATED
mouse/Mapk3	Q63844	10090	GO:0042473	outer ear morphogenesis	ARBA:ARBA00087231	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0043330	response to exogenous dsRNA	ARBA:ARBA00043583	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0051493	regulation of cytoskeleton organization	ARBA:ARBA00027391	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0060020	Bergmann glial cell differentiation	ARBA:ARBA00089456	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0061308	cardiac neural crest cell development involved in heart development	ARBA:ARBA00089518	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0071356	cellular response to tumor necrosis factor	ARBA:ARBA00092549	ENTAILED	False	tnf_signaling		tnf_signaling:tak1_complex_ikkbeta_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0072584	caveolin-mediated endocytosis	ARBA:ARBA00028693	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Mapk3	Q63844	10090	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cascade|kinase_p	KEEP_AS_NON_CORE
mouse/Megf10	Q6DIB5	10090	GO:0048468	cell development	ARBA:ARBA00028665	NOT_ENTAILED	False	primordial_germ_cell_specification			cobalamin_absorption_transport|complex_i_assembly_factors|erbb2_signaling|notch_signaling|phagocytic_engulfment|wnt_signaling	MARK_AS_OVER_ANNOTATED
mouse/Mtor	Q9JLN9	10090	GO:0019216	regulation of lipid metabolic process	ARBA:ARBA00028119	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0031346	positive regulation of cell projection organization	ARBA:ARBA00086237	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0045792	negative regulation of cell size	ARBA:ARBA00084279	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0048714	positive regulation of oligodendrocyte differentiation	ARBA:ARBA00090895	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0050795	regulation of behavior	ARBA:ARBA00091595	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0051155	positive regulation of striated muscle cell differentiation	ARBA:ARBA00087718	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Mtor	Q9JLN9	10090	GO:0051896	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ARBA:ARBA00089772	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	ACCEPT
mouse/Mtor	Q9JLN9	10090	GO:0120035	regulation of plasma membrane bounded cell projection organization	ARBA:ARBA00028050	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insu	KEEP_AS_NON_CORE
mouse/Nf1	Q04690	10090	GO:0014037	Schwann cell differentiation	ARBA:ARBA00087929	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|gtpase_switch|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|nucleokinesis|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
mouse/Nf1	Q04690	10090	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|gtpase_switch|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|nucleokinesis|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
mouse/Nf1	Q04690	10090	GO:0050807	regulation of synapse organization	ARBA:ARBA00029186	NO_MODULE	False				canonical_nlrp3_inflammasome|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|gtpase_switch|metazoan_autophagosome_biogenesis|mitophagy|nlrp3_inflammasome|nucleokinesis|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	KEEP_AS_NON_CORE
mouse/Nkx2-5	P42582	10090	GO:0009888	tissue development	ARBA:ARBA00028065	ENTAILED	False	neural_crest_gene_regulatory_network		neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MARK_AS_OVER_ANNOTATED
mouse/Notch1	Q01705	10090	GO:0001525	angiogenesis	ARBA:ARBA00090097	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0001701	in utero embryonic development	ARBA:ARBA00089616	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0001947	heart looping	ARBA:ARBA00091286	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0002011	morphogenesis of an epithelial sheet	ARBA:ARBA00087846	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0002064	epithelial cell development	ARBA:ARBA00027130	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0002437	inflammatory response to antigenic stimulus	ARBA:ARBA00089205	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0006959	humoral immune response	ARBA:ARBA00026316	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0010001	glial cell differentiation	ARBA:ARBA00091307	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0010718	positive regulation of epithelial to mesenchymal transition	ARBA:ARBA00085207	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0010720	positive regulation of cell development	ARBA:ARBA00034380	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0030326	embryonic limb morphogenesis	ARBA:ARBA00087370	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0030513	positive regulation of BMP signaling pathway	ARBA:ARBA00086892	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0030858	positive regulation of epithelial cell differentiation	ARBA:ARBA00088239	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0035850	epithelial cell differentiation involved in kidney development	ARBA:ARBA00092304	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0045165	cell fate commitment	ARBA:ARBA00043601	NOT_ENTAILED	False	cardiac_specification_network			apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	ACCEPT
mouse/Notch1	Q01705	10090	GO:0048589	developmental growth	ARBA:ARBA00044390	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0048608	reproductive structure development	ARBA:ARBA00028277	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0048844	artery morphogenesis	ARBA:ARBA00090567	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0070986	left/right axis specification	ARBA:ARBA00086187	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0072012	glomerulus vasculature development	ARBA:ARBA00089490	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:0072080	nephron tubule development	ARBA:ARBA00089540	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Notch1	Q01705	10090	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	ARBA:ARBA00088364	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|canonical_nlrp3_inflammasome|erbb2_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|mitochondrial_upr|nlrp3_inflammasome|notch_signaling|retinal_determination_network|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0001764	neuron migration	ARBA:ARBA00089626	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0003309	type B pancreatic cell differentiation	ARBA:ARBA00088307	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0009653	anatomical structure morphogenesis	ARBA:ARBA00026583	ENTAILED	False	germ_layer_specification		germ_layer_specification:ectoderm_sox2|germ_layer_specification:endoderm_foxa2|germ_layer_specification:endoderm_gata|germ_layer_specification:endoderm_sox17|germ_layer_specification:mesendoderm_eomes|germ_layer_specification:mesendoderm_mixl1|germ_layer_specification:mesoderm_tbxt	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|heat_shock_response|hedgehog_signaling|kit_signal	MARK_AS_OVER_ANNOTATED
mouse/Pax6	P63015	10090	GO:0021510	spinal cord development	ARBA:ARBA00084979	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0021537	telencephalon development	ARBA:ARBA00084940	NOT_ENTAILED	False	nucleokinesis			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0030334	regulation of cell migration	ARBA:ARBA00028900	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0045664	regulation of neuron differentiation	ARBA:ARBA00084592	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0048708	astrocyte differentiation	ARBA:ARBA00090893	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0050767	regulation of neurogenesis	ARBA:ARBA00089678	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pax6	P63015	10090	GO:0050877	nervous system process	ARBA:ARBA00029146	NOT_ENTAILED	False	retinoid_visual_cycle			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	REMOVE
mouse/Pax6	P63015	10090	GO:0051656	establishment of organelle localization	ARBA:ARBA00028716	NOT_ENTAILED	False	nucleokinesis			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	MARK_AS_OVER_ANNOTATED
mouse/Pax6	P63015	10090	GO:0060041	retina development in camera-type eye	ARBA:ARBA00089482	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedg	KEEP_AS_NON_CORE
mouse/Pld4	Q8BG07	10090	GO:1900015	regulation of cytokine production involved in inflammatory response	ARBA:ARBA00092589	NO_MODULE	False				gpi_anchor_remodeling|muth_independent_mismatch_repair|phenylacetate_catabolism	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0009966	regulation of signal transduction	ARBA:ARBA00027204	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0010604	positive regulation of macromolecule metabolic process	ARBA:ARBA00026482	NOT_ENTAILED	False	maternal_to_zygotic_transition			apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0010648	negative regulation of cell communication	ARBA:ARBA00026586	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0010977	negative regulation of neuron projection development	ARBA:ARBA00084554	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0023057	negative regulation of signaling	ARBA:ARBA00026312	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0051726	regulation of cell cycle	ARBA:ARBA00029144	ENTAILED	False	metaphase_anaphase_transition_and_mitotic_exit		metaphase_anaphase_transition_and_mitotic_exit:cdc14_scer|metaphase_anaphase_transition_and_mitotic_exit:cdc20_coactivator|metaphase_anaphase_transition_and_mitotic_exit:cdh1_coactivator|metaphase_anaphase_transition_and_mitotic_exit:clp1_spom|metaphase_anaphase_transition_and_mitotic_exit:pp2a_b55_exit	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metazoan_autophagosome_biogenesis|nlrp3_inflammasome|pept	KEEP_AS_NON_CORE
mouse/Pten	O08586	10090	GO:0060044	negative regulation of cardiac muscle cell proliferation	ARBA:ARBA00089480	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cerebellum_development|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|gpi_anchor_remodeling|heat_shock_response|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_a	KEEP_AS_NON_CORE
mouse/Rbpj	P31266	10090	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|cerebellum_development:atoh1_glutamatergic_identity|cerebellum_development:engrailed_foliation_program|cerebellum_development:gbx2_hindbrain_identity|cerebellum_development:ptf1a_gabaergic_identity|cerebellum_development:purkinje_rora_program|neural_crest_gene_regulatory_network:ets1_emigration|neural_crest_gene_regulatory_network:msx1_border|neural_crest_gene_regulatory_network:myc_competence|neural_crest_gene_regulatory_network:pax3_border|neural_crest_gene_regulatory_network:pax7_border|neural_crest_gene_regulatory_network:pou5f3_competence|neural_crest_gene_regulatory_network:sox10_spec|neural_crest_gene_regulatory_network:sox8_spec|neural_crest_gene_regulatory_network:sox9_chondrogenesis|neural_crest_gene_regulatory_network:sox9_spec|neural_crest_gene_regulatory_network:tfap2a_border|neural_crest_gene_regulatory_network:tfap2a_craniofacial|neural_crest_gene_regulatory_network:tfap2a_spec|neural_crest_gene_regulatory_network:tfap2b_spec|neural_crest_gene_regulatory_network:tfap2c_border|neural_crest_gene_regulatory_network:twist1_ectomesenchyme|neural_crest_gene_regulatory_network:zic1_border|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cgas_sting_signaling|complex_i_assembly_factors|cuproptosis|early_metazoan_development|er_unfolded_protein_response|ferroptosis|g1_s_transition|germ_layer_specification|heat_shock_response|hedgehog_signaling|kit_signali	KEEP_AS_NON_CORE
mouse/Sdhaf2	A0A494B8X4	10090	GO:0010719	negative regulation of epithelial to mesenchymal transition	ARBA:ARBA00085215	NO_MODULE	False					UNDECIDED
mouse/Sdhaf2	A0A494B8X4	10090	GO:0090090	negative regulation of canonical Wnt signaling pathway	ARBA:ARBA00027950	NO_MODULE	False					UNDECIDED
mouse/Sirt2	Q8VDQ8	10090	GO:0022011	myelination in peripheral nervous system	ARBA:ARBA00091367	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|wnt_signaling	ACCEPT
mouse/Sirt2	Q8VDQ8	10090	GO:0031641	regulation of myelination	ARBA:ARBA00087391	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|wnt_signaling	ACCEPT
mouse/Sirt2	Q8VDQ8	10090	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|wnt_signaling	KEEP_AS_NON_CORE
mouse/Sirt2	Q8VDQ8	10090	GO:0045599	negative regulation of fat cell differentiation	ARBA:ARBA00085192	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling|phenylacetate_catabolism|wnt_signaling	ACCEPT
mouse/Src	P05480	10090	GO:0007155	cell adhesion	ARBA:ARBA00028946	ENTAILED	False	neurexin_transsynaptic_adhesion		neurexin_transsynaptic_adhesion:cerebellin_activity|neurexin_transsynaptic_adhesion:gluD_activity	canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|nlrp3_	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:0007276	gamete generation	ARBA:ARBA00028211	NOT_ENTAILED	False	primordial_germ_cell_specification			canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:0010628	positive regulation of gene expression	ARBA:ARBA00026655	NOT_ENTAILED	False	maternal_to_zygotic_transition			canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:0036120	cellular response to platelet-derived growth factor stimulus	ARBA:ARBA00089982	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:0070301	cellular response to hydrogen peroxide	ARBA:ARBA00092154	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:0070374	positive regulation of ERK1 and ERK2 cascade	ARBA:ARBA00085202	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:1903829	positive regulation of protein localization	ARBA:ARBA00047251	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Src	P05480	10090	GO:1904385	cellular response to angiotensin	ARBA:ARBA00089858	NO_MODULE	False				canonical_nlrp3_inflammasome|coenzyme_a_biosynthesis|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|kit_signaling|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_upr|neurex	KEEP_AS_NON_CORE
mouse/Stat1	P42225	10090	GO:0007259	cell surface receptor signaling pathway via JAK-STAT	ARBA:ARBA00034574	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
mouse/Stat1	P42225	10090	GO:0008283	cell population proliferation	ARBA:ARBA00035743	NOT_ENTAILED	False	nucleokinesis			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
mouse/Stat1	P42225	10090	GO:0042981	regulation of apoptotic process	ARBA:ARBA00027086	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
mouse/Stat1	P42225	10090	GO:0051093	negative regulation of developmental process	ARBA:ARBA00027583	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
mouse/Stat1	P42225	10090	GO:0051607	defense response to virus	ARBA:ARBA00026923	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	KEEP_AS_NON_CORE
mouse/Stat1	P42225	10090	GO:0060333	type II interferon-mediated signaling pathway	ARBA:ARBA00090813	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
mouse/Stat1	P42225	10090	GO:0060337	type I interferon-mediated signaling pathway	ARBA:ARBA00033815	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|cuproptosis|early_metazoan_development|er_unfolded_protein_response|erbb2_signaling|ferroptosis|g1_s_transition|germ_layer_specification|heat_sho	ACCEPT
mouse/Syk	P48025	10090	GO:0043306	positive regulation of mast cell degranulation	ARBA:ARBA00086079	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	KEEP_AS_NON_CORE
mouse/Syk	P48025	10090	GO:0043366	beta selection	ARBA:ARBA00086189	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	KEEP_AS_NON_CORE
mouse/Syk	P48025	10090	GO:0046638	positive regulation of alpha-beta T cell differentiation	ARBA:ARBA00091954	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	KEEP_AS_NON_CORE
mouse/Syk	P48025	10090	GO:0046641	positive regulation of alpha-beta T cell proliferation	ARBA:ARBA00091977	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	KEEP_AS_NON_CORE
mouse/Syk	P48025	10090	GO:0050850	positive regulation of calcium-mediated signaling	ARBA:ARBA00091707	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	ACCEPT
mouse/Syk	P48025	10090	GO:0050851	antigen receptor-mediated signaling pathway	ARBA:ARBA00091706	NO_MODULE	False				cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|erbb2_signaling|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|integrin_fak_src_signaling|intrafla	ACCEPT
mouse/Tert	O70372	10090	GO:0008284	positive regulation of cell population proliferation	ARBA:ARBA00027538	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|heat_shock_response|mitochondrial_complex_ii|nlrp3_inflammasome|sphingolipid_de_novo_synthesis|wnt_signaling	KEEP_AS_NON_CORE
mouse/Tlr11	Q6R5P0	10090	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False					KEEP_AS_NON_CORE
mouse/Tlr12	Q6QNU9	10090	GO:0051707	response to other organism	ARBA:ARBA00029118	NO_MODULE	False					KEEP_AS_NON_CORE
mouse/Tnfrsf1a	P25118	10090	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Tnfrsf1a	P25118	10090	GO:0032496	response to lipopolysaccharide	ARBA:ARBA00084357	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MODIFY
mouse/Tnfrsf1a	P25118	10090	GO:0043065	positive regulation of apoptotic process	ARBA:ARBA00027745	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MODIFY
mouse/Tnfrsf1a	P25118	10090	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Tnfrsf1a	P25118	10090	GO:0051241	negative regulation of multicellular organismal process	ARBA:ARBA00033877	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MARK_AS_OVER_ANNOTATED
mouse/Tnfrsf1a	P25118	10090	GO:0071396	cellular response to lipid	ARBA:ARBA00027803	NO_MODULE	False				complex_i_assembly_factors|heat_shock_response|nfkb_canonical_signaling|nlrp3_inflammasome|notch_signaling	MODIFY
mouse/Trp53	P02340	10090	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	ENTAILED	False	nrf_oxidative_stress_response		nrf_oxidative_stress_response:cnc_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0009410	response to xenobiotic stimulus	ARBA:ARBA00092608	MODULE_INCOMPLETE	False	phenylacetate_catabolism	phenylacetate_catabolism:phenylacetate_activation|phenylacetate_catabolism:phenylacetyl_coa_epoxidation|phenylacetate_catabolism:paaJ_thiolysis	phenylacetate_catabolism:paaG_isomerase	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0009411	response to UV	ARBA:ARBA00028103	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0010165	response to X-ray	ARBA:ARBA00090977	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0048468	cell development	ARBA:ARBA00028665	ENTAILED	False	primordial_germ_cell_specification		primordial_germ_cell_specification:germ_plasm_nanos|primordial_germ_cell_specification:germ_plasm_vasa|primordial_germ_cell_specification:pgc_tripartite_network	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0051053	negative regulation of DNA metabolic process	ARBA:ARBA00088036	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
mouse/Trp53	P02340	10090	GO:0097190	apoptotic signaling pathway	ARBA:ARBA00028296	NOT_ENTAILED	False	bcl2_family_momp_control			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
mouse/Trp53	P02340	10090	GO:2001242	regulation of intrinsic apoptotic signaling pathway	ARBA:ARBA00087888	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	ACCEPT
mouse/Txn1	P10639	10090	GO:0019725	cellular homeostasis	ARBA:ARBA00027105	ENTAILED	False	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:cytosolic_trx_activity	aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|heat_shock_response|nlrp3_inflammasome|oligosaccharyltransferase_complex	MODIFY
rat/Akt1	P47196	10116	GO:0010765	positive regulation of sodium ion transport	ARBA:ARBA00085241	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_receptor_s	KEEP_AS_NON_CORE
rat/Akt1	P47196	10116	GO:0032869	cellular response to insulin stimulus	ARBA:ARBA00085489	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	apoptotic_execution_phase|canonical_nlrp3_inflammasome|cgas_sting_signaling|coenzyme_a_biosynthesis|complex_i_assembly_factors|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|intraflagellar_tra	KEEP_AS_NON_CORE
rat/Casp3	P55213	10116	GO:0007413	axonal fasciculation	ARBA:ARBA00084186	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_cat	MARK_AS_OVER_ANNOTATED
rat/Casp3	P55213	10116	GO:0010212	response to ionizing radiation	ARBA:ARBA00090590	NO_MODULE	False				apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_cat	MARK_AS_OVER_ANNOTATED
rat/Casp3	P55213	10116	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|cerebellum_development|neural_crest_gene_regulatory_network|nucleokinesis|retinal_determination_network			apoptotic_execution_phase|canonical_nlrp3_inflammasome|complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|erbb2_signaling|g1_s_transition|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|necroptosis|nlrp3_inflammasome|phenylacetate_cat	MARK_AS_OVER_ANNOTATED
rat/Cd48	P10252	10116	GO:0045321	leukocyte activation	ARBA:ARBA00091994	NO_MODULE	False				canonical_nlrp3_inflammasome|egfr_signaling|neurexin_transsynaptic_adhesion|nlrp3_inflammasome|notch_signaling	ACCEPT
rat/Ckmt2	P09605	10116	GO:0007519	skeletal muscle tissue development	ARBA:ARBA00086337	NO_MODULE	False				coenzyme_a_biosynthesis|mitochondrial_complex_iii|phosphocreatine_shuttle|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis	MARK_AS_OVER_ANNOTATED
rat/Crot	P11466	10116	GO:0015908	fatty acid transport	ARBA:ARBA00043302	NOT_ENTAILED	False	carnitine_shuttle			alginate_o_acetylation|bacterial_l_carnitine_catabolism	MODIFY
rat/Egfr	G3V6K6	10116	GO:0021537	telencephalon development	ARBA:ARBA00084940	NOT_ENTAILED	False	nucleokinesis			coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
rat/Egfr	G3V6K6	10116	GO:0038134	ERBB2-EGFR signaling pathway	ARBA:ARBA00087731	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
rat/Egfr	G3V6K6	10116	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	ARBA:ARBA00086227	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
rat/Egfr	G3V6K6	10116	GO:0050679	positive regulation of epithelial cell proliferation	ARBA:ARBA00089519	NO_MODULE	False				coenzyme_a_biosynthesis|egfr_signaling|erbb2_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
rat/Elovl7	D4ADY9	10116	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	fatty_acid_elongation_cycle		fatty_acid_elongation_cycle:elovl_activity|fatty_acid_elongation_cycle:kcs_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
rat/Gstt1	Q01579	10116	GO:0006749	glutathione metabolic process	ARBA:ARBA00027824	NOT_ENTAILED	False	glutathione_biosynthesis|glutathione_synthesis_gamma_glutamyl_cycle			complex_i_assembly_factors|methionine_biosynthesis|nrf_oxidative_stress_response|phenylacetate_catabolism	ACCEPT
rat/Gstt1	Q01579	10116	GO:0009751	response to salicylic acid	ARBA:ARBA00028903	NO_MODULE	False				complex_i_assembly_factors|methionine_biosynthesis|nrf_oxidative_stress_response|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
rat/Hdc	P16453	10116	GO:0042401	biogenic amine biosynthetic process	ARBA:ARBA00028120	NOT_ENTAILED	False	catecholamine_biosynthesis|polyamine_metabolism|serotonin_melatonin_biosynthesis|tryptophan_biosynthesis			heat_shock_response|nlrp3_inflammasome|type_ii_fatty_acid_synthesis	MODIFY
rat/Hspa5	P06761	10116	GO:0034976	response to endoplasmic reticulum stress	ARBA:ARBA00027479	ENTAILED	False	er_unfolded_protein_response		er_unfolded_protein_response:bip_sensor_sequestration	apoptotic_execution_phase|bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|hedgehog_signaling|linc_complex|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|	ACCEPT
rat/Hspa8	P63018	10116	GO:0001916	positive regulation of T cell mediated cytotoxicity	ARBA:ARBA00091259	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_ana	KEEP_AS_NON_CORE
rat/Hspa8	P63018	10116	GO:0043066	negative regulation of apoptotic process	ARBA:ARBA00027746	NO_MODULE	False				apoptotic_execution_phase|bacterial_nucleotide_excision_repair|canonical_nlrp3_inflammasome|cct_chaperonin_folding|ciliary_transition_zone|coenzyme_q10_biosynthesis|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|ferroptosis|heat_shock_response|hedgehog_signaling|linc_complex|metaphase_ana	KEEP_AS_NON_CORE
rat/Ldhb	P42123	10116	GO:0019674	NAD+ metabolic process	ARBA:ARBA00034606	NOT_ENTAILED	False	glycerol_phosphate_shuttle|kynurenine_nad_de_novo|malate_aspartate_shuttle|nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal			complex_i_assembly_factors|gluconeogenesis_human_substrates|heat_shock_response|lactate_fermentation_and_bpg_shunt|nlrp3_inflammasome	KEEP_AS_NON_CORE
rat/Lss	P48450	10116	GO:0006695	cholesterol biosynthetic process	ARBA:ARBA00087369	ENTAILED	True	sterol_commitment_squalene_to_lanosterol		sterol_commitment_squalene_to_lanosterol:lss_activity	methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
rat/Mapk1	P63086	10116	GO:0032872	regulation of stress-activated MAPK cascade	ARBA:ARBA00026638	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0035094	response to nicotine	ARBA:ARBA00089505	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0045727	positive regulation of translation	ARBA:ARBA00084181	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0046697	decidualization	ARBA:ARBA00092194	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0051493	regulation of cytoskeleton organization	ARBA:ARBA00027391	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0070371	ERK1 and ERK2 cascade	ARBA:ARBA00085205	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	ACCEPT
rat/Mapk1	P63086	10116	GO:0071375	cellular response to peptide hormone stimulus	ARBA:ARBA00043567	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|intraflagellar_	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0071396	cellular response to lipid	ARBA:ARBA00027803	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0072584	caveolin-mediated endocytosis	ARBA:ARBA00028693	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:0090170	regulation of Golgi inheritance	ARBA:ARBA00028400	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Mapk1	P63086	10116	GO:2000641	regulation of early endosome to late endosome transport	ARBA:ARBA00028332	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|hedgehog_signaling|hippo_signaling|insulin_recepto	KEEP_AS_NON_CORE
rat/Oaz1	P54370	10116	GO:0045732	positive regulation of protein catabolic process	ARBA:ARBA00026548	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|polyamine_metabolism|sphingolipid_de_novo_synthesis	ACCEPT
rat/Oaz1	P54370	10116	GO:1902268	negative regulation of polyamine transmembrane transport	ARBA:ARBA00089136	NO_MODULE	False				apoptotic_execution_phase|complex_i_assembly_factors|polyamine_metabolism|sphingolipid_de_novo_synthesis	ACCEPT
rat/Pgp	D3ZDK7	10116	GO:0006114	glycerol biosynthetic process	ARBA:ARBA00084233	NO_MODULE	False				cerebellum_development|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	ACCEPT
rat/Pgp	D3ZDK7	10116	GO:0006650	glycerophospholipid metabolic process	ARBA:ARBA00028631	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	cerebellum_development|g2_m_transition|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	KEEP_AS_NON_CORE
rat/Prkaa2	Q09137	10116	GO:0031000	response to caffeine	ARBA:ARBA00084610	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	KEEP_AS_NON_CORE
rat/Prkaa2	Q09137	10116	GO:0045821	positive regulation of glycolytic process	ARBA:ARBA00086348	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	ACCEPT
rat/Prkaa2	Q09137	10116	GO:0055089	fatty acid homeostasis	ARBA:ARBA00084799	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	ACCEPT
rat/Prkaa2	Q09137	10116	GO:0071277	cellular response to calcium ion	ARBA:ARBA00092869	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	KEEP_AS_NON_CORE
rat/Prkaa2	Q09137	10116	GO:0071333	cellular response to glucose stimulus	ARBA:ARBA00093092	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	ACCEPT
rat/Prkaa2	Q09137	10116	GO:0097009	energy homeostasis	ARBA:ARBA00090302	NO_MODULE	False				cgas_sting_signaling|ciliary_transition_zone|coenzyme_a_biosynthesis|complex_i_assembly_factors|egfr_signaling|er_unfolded_protein_response|ferroptosis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_	ACCEPT
rat/Qdpr	P11348	10116	GO:0042558	pteridine-containing compound metabolic process	ARBA:ARBA00027196	ENTAILED	False	tetrahydrobiopterin_metabolism		tetrahydrobiopterin_metabolism:qdpr_activity	complex_i_assembly_factors|heat_shock_response|hydroxyproline_catabolism|nlrp3_inflammasome	ACCEPT
rat/Sqle	P52020	10116	GO:0008203	cholesterol metabolic process	ARBA:ARBA00034389	ENTAILED	False	sterol_commitment_squalene_to_lanosterol		sterol_commitment_squalene_to_lanosterol:sqle_activity	complex_i_assembly_factors	ACCEPT
rat/Sstr5	P30938	10116	GO:0071385	cellular response to glucocorticoid stimulus	ARBA:ARBA00092516	NO_MODULE	False				cerebellum_development|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|notch_signaling	ACCEPT
rat/Tp53	P10361	10116	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	ENTAILED	False	nrf_oxidative_stress_response		nrf_oxidative_stress_response:cnc_tf	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:0009410	response to xenobiotic stimulus	ARBA:ARBA00092608	MODULE_INCOMPLETE	False	phenylacetate_catabolism	phenylacetate_catabolism:phenylacetate_activation|phenylacetate_catabolism:phenylacetyl_coa_epoxidation|phenylacetate_catabolism:paaJ_thiolysis	phenylacetate_catabolism:paaG_isomerase	apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:0009411	response to UV	ARBA:ARBA00028103	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:0010165	response to X-ray	ARBA:ARBA00090977	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:0051053	negative regulation of DNA metabolic process	ARBA:ARBA00088036	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	MARK_AS_OVER_ANNOTATED
rat/Tp53	P10361	10116	GO:0071456	cellular response to hypoxia	ARBA:ARBA00092776	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:0097190	apoptotic signaling pathway	ARBA:ARBA00028296	NOT_ENTAILED	False	bcl2_family_momp_control			apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Tp53	P10361	10116	GO:2001242	regulation of intrinsic apoptotic signaling pathway	ARBA:ARBA00087888	NO_MODULE	False				apoptotic_execution_phase|bacterial_recbcd_end_resection|body_axis_specification|canonical_nlrp3_inflammasome|cardiac_specification_network|cerebellum_development|cgas_sting_signaling|ciliary_transition_zone|cuproptosis|early_metazoan_development|egfr_signaling|er_unfolded_protein_response|erbb2_sig	KEEP_AS_NON_CORE
rat/Uggt1	Q9JLA3	10116	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			osmoregulated_periplasmic_glucan_biosynthesis	KEEP_AS_NON_CORE
worm/F44E5.4	G5ECU5	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/aak-2	Q95ZQ4	6239	GO:0043050	nematode pharyngeal pumping	ARBA:ARBA00084835	NO_MODULE	False				c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	KEEP_AS_NON_CORE
worm/age-1	Q94125	6239	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	c_elegans_daf2_insulin_signaling|cardiac_specification_network|nucleokinesis|retinal_determination_network			coenzyme_a_biosynthesis|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
worm/akt-1	Q17941	6239	GO:0008286	insulin receptor signaling pathway	ARBA:ARBA00092359	ENTAILED	True	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome	ACCEPT
worm/akt-1	Q17941	6239	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	MODULE_INCOMPLETE	True	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:akt1_kinase|c_elegans_daf2_insulin_signaling:akt2_kinase|c_elegans_daf2_insulin_signaling:sgk1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	ACCEPT
worm/akt-1	Q17941	6239	GO:0008582	regulation of synaptic assembly at neuromuscular junction	ARBA:ARBA00085089	NO_MODULE	False				c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	KEEP_AS_NON_CORE
worm/akt-1	Q17941	6239	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	c_elegans_mutator_22g_rna_amplification|maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	KEEP_AS_NON_CORE
worm/akt-1	Q17941	6239	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	er_unfolded_protein_response|nrf_oxidative_stress_response		er_unfolded_protein_response:ire1_kinase|nrf_oxidative_stress_response:gsk3_kinase	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mito	KEEP_AS_NON_CORE
worm/akt-1	Q17941	6239	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	er_unfolded_protein_response|hippo_signaling|nlr_signaling		er_unfolded_protein_response:ire1_kinase|hippo_signaling:lats_kinase|hippo_signaling:mst_kinase|nlr_signaling:tak1_complex_ikkbeta_kinase	c_elegans_daf2_insulin_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_bioge	ACCEPT
worm/akt-2	Q9XTG7	6239	GO:0008286	insulin receptor signaling pathway	ARBA:ARBA00092359	ENTAILED	True	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome	ACCEPT
worm/akt-2	Q9XTG7	6239	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	MODULE_INCOMPLETE	True	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:akt1_kinase|c_elegans_daf2_insulin_signaling:akt2_kinase|c_elegans_daf2_insulin_signaling:sgk1_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	KEEP_AS_NON_CORE
worm/akt-2	Q9XTG7	6239	GO:0008582	regulation of synaptic assembly at neuromuscular junction	ARBA:ARBA00085089	NO_MODULE	False				c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	KEEP_AS_NON_CORE
worm/akt-2	Q9XTG7	6239	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	c_elegans_mutator_22g_rna_amplification|maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	KEEP_AS_NON_CORE
worm/anc-1	Q9N4M4	6239	GO:0006997	nucleus organization	ARBA:ARBA00033484	NO_MODULE	False				mitochondrial_complex_ii	KEEP_AS_NON_CORE
worm/anc-1	Q9N4M4	6239	GO:0007097	nuclear migration	ARBA:ARBA00026920	NOT_ENTAILED	True	nucleokinesis			mitochondrial_complex_ii	KEEP_AS_NON_CORE
worm/apx-1	P41990	6239	GO:0030154	cell differentiation	ARBA:ARBA00027429	NOT_ENTAILED	False	c_elegans_p_granule_assembly_segregation|cardiac_specification_network|nucleokinesis|primordial_germ_cell_specification			erbb2_signaling|notch_signaling	ACCEPT
worm/apx-1	P41990	6239	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	NOT_ENTAILED	False	c_elegans_dbl1_body_size_signaling			erbb2_signaling|notch_signaling	KEEP_AS_NON_CORE
worm/atg-16.2	Q09406	6239	GO:0035973	aggrephagy	ARBA:ARBA00091938	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|dolichol_phosphate_sugar_donor_supply|egfr_signaling|hedgehog_signaling|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_dynamics|mitoph	ACCEPT
worm/atg-5	Q3V5I7	6239	GO:0007033	vacuole organization	ARBA:ARBA00033898	NO_MODULE	False				alginate_o_acetylation|metazoan_autophagosome_biogenesis	MODIFY
worm/atg-5	Q3V5I7	6239	GO:0016236	macroautophagy	ARBA:ARBA00027245	ENTAILED	True	metazoan_autophagosome_biogenesis		metazoan_autophagosome_biogenesis:atg5_e3	alginate_o_acetylation	ACCEPT
worm/cdc-48	P54811	6239	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False				bacterial_nucleotide_excision_repair|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
worm/cdc-48	P54811	6239	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				bacterial_nucleotide_excision_repair|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/cdc-48	P54811	6239	GO:0032880	regulation of protein localization	ARBA:ARBA00026609	NO_MODULE	False				bacterial_nucleotide_excision_repair|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/cdc-48	P54811	6239	GO:0034976	response to endoplasmic reticulum stress	ARBA:ARBA00027479	NOT_ENTAILED	False	er_unfolded_protein_response			bacterial_nucleotide_excision_repair|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|complex_i_assembly_factors|heat_shock_response|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/ced-4	P30429	6239	GO:0006915	apoptotic process	ARBA:ARBA00027755	ENTAILED	False	c_elegans_core_apoptosis		c_elegans_core_apoptosis:ced4_caspase_activator|c_elegans_core_apoptosis:ced9_bh3_receptor	c_elegans_p_granule_assembly_segregation|dolichol_phosphate_sugar_donor_supply|heat_shock_response|sphingolipid_de_novo_synthesis	MODIFY
worm/ced-4	P30429	6239	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	c_elegans_daf2_insulin_signaling|cardiac_specification_network|nucleokinesis|retinal_determination_network			c_elegans_core_apoptosis|c_elegans_p_granule_assembly_segregation|dolichol_phosphate_sugar_donor_supply|heat_shock_response|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
worm/ced-6	O76337	6239	GO:0043277	apoptotic cell clearance	ARBA:ARBA00086522	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|egfr_signaling|erbb2_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagoc	KEEP_AS_NON_CORE
worm/cgh-1	Q95YF3	6239	GO:0017148	negative regulation of translation	ARBA:ARBA00027301	NO_MODULE	False				bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylaceta	ACCEPT
worm/cgh-1	Q95YF3	6239	GO:0033962	P-body assembly	ARBA:ARBA00086154	NO_MODULE	False				bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylaceta	ACCEPT
worm/chc-1	P34574	6239	GO:0045807	positive regulation of endocytosis	ARBA:ARBA00086449	NO_MODULE	False				complex_i_accessory_subunits|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|vesicle_coat_budding	MODIFY
worm/che-3	Q19542	6239	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NOT_ENTAILED	False	c_elegans_dbl1_body_size_signaling			hedgehog_signaling|intraflagellar_transport|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	KEEP_AS_NON_CORE
worm/che-3	Q19542	6239	GO:0060271	cilium assembly	ARBA:ARBA00027837	ENTAILED	True	intraflagellar_transport		intraflagellar_transport:che3_heavy_chain	hedgehog_signaling|methylcitrate_cycle|nucleokinesis|phenylacetate_catabolism	ACCEPT
worm/daf-11	Q8I4N4	6239	GO:0009266	response to temperature stimulus	ARBA:ARBA00026893	NOT_ENTAILED	False	heat_shock_response			c_elegans_cgmp_sensory_transduction	MARK_AS_OVER_ANNOTATED
worm/daf-11	Q8I4N4	6239	GO:0009581	detection of external stimulus	ARBA:ARBA00027562	NO_MODULE	False				c_elegans_cgmp_sensory_transduction	KEEP_AS_NON_CORE
worm/daf-11	Q8I4N4	6239	GO:0009582	detection of abiotic stimulus	ARBA:ARBA00027563	NO_MODULE	False				c_elegans_cgmp_sensory_transduction	MARK_AS_OVER_ANNOTATED
worm/daf-11	Q8I4N4	6239	GO:0042330	taxis	ARBA:ARBA00028791	NO_MODULE	False				c_elegans_cgmp_sensory_transduction	KEEP_AS_NON_CORE
worm/daf-16	O16850	6239	GO:0008286	insulin receptor signaling pathway	ARBA:ARBA00092359	MODULE_INCOMPLETE	True	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:daf16_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network	ACCEPT
worm/daf-16	O16850	6239	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	ENTAILED	True	c_elegans_lysosomal_lipid_signaling		c_elegans_lysosomal_lipid_signaling:hlh30_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early_metazoan	ACCEPT
worm/daf-16	O16850	6239	GO:0009896	positive regulation of catabolic process	ARBA:ARBA00028093	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0010883	regulation of lipid storage	ARBA:ARBA00084945	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0031349	positive regulation of defense response	ARBA:ARBA00028260	MODULE_INCOMPLETE	False	cgas_sting_signaling	cgas_sting_signaling:nucleic_acid_sensing|cgas_sting_signaling:sting_activation	cgas_sting_signaling:cgas_dsdna_sensor|cgas_sting_signaling:irf3_transcription_factor|cgas_sting_signaling:relish_transcription_factor	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	ENTAILED	True	nrf_oxidative_stress_response		nrf_oxidative_stress_response:cnc_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0040015	negative regulation of multicellular organism growth	ARBA:ARBA00086733	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0042594	response to starvation	ARBA:ARBA00034570	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-16	O16850	6239	GO:0050778	positive regulation of immune response	ARBA:ARBA00028646	MODULE_INCOMPLETE	False	cgas_sting_signaling	cgas_sting_signaling:nucleic_acid_sensing|cgas_sting_signaling:sting_activation	cgas_sting_signaling:cgas_dsdna_sensor|cgas_sting_signaling:irf3_transcription_factor|cgas_sting_signaling:relish_transcription_factor	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/daf-18	G5EE01	6239	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	NOT_ENTAILED	False	c_elegans_dbl1_body_size_signaling			c_elegans_daf2_insulin_signaling|g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|retinal_determination_network	KEEP_AS_NON_CORE
worm/dve-1	Q86MI0	6239	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immun	ACCEPT
worm/dyf-11	Q17595	6239	GO:0048513	animal organ development	ARBA:ARBA00029247	ENTAILED	False	nucleokinesis		nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone	MARK_AS_OVER_ANNOTATED
worm/dyf-11	Q17595	6239	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	nucleokinesis		nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone	MARK_AS_OVER_ANNOTATED
worm/dyf-11	Q17595	6239	GO:0070507	regulation of microtubule cytoskeleton organization	ARBA:ARBA00033510	NO_MODULE	False				ciliary_transition_zone|nucleokinesis	MARK_AS_OVER_ANNOTATED
worm/dyf-2	G5ECZ4	6239	GO:0008104	intracellular protein localization	ARBA:ARBA00028253	NO_MODULE	False					MODIFY
worm/dyf-2	G5ECZ4	6239	GO:0044782	cilium organization	ARBA:ARBA00027540	NOT_ENTAILED	False	ciliary_transition_zone|intraflagellar_transport				KEEP_AS_NON_CORE
worm/dyn-1	P39055	6239	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	NOT_ENTAILED	True	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis			chylomicron_assembly_secretion|ciliary_transition_zone|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nucleokinesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle	ACCEPT
worm/dyn-1	P39055	6239	GO:0012501	programmed cell death	ARBA:ARBA00028943	NOT_ENTAILED	False	c_elegans_core_apoptosis			chylomicron_assembly_secretion|ciliary_transition_zone|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|nucleokinesis|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle	MODIFY
worm/elt-2	Q10655	6239	GO:0009888	tissue development	ARBA:ARBA00028065	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	MODIFY
worm/ent-1	G5EDJ3	6239	GO:0015858	nucleoside transport	ARBA:ARBA00027644	NO_MODULE	False					ACCEPT
worm/fzo-1	Q23424	6239	GO:0007005	mitochondrion organization	ARBA:ARBA00026723	MODULE_INCOMPLETE	True	mitochondrial_dynamics	mitochondrial_dynamics:eat3_imm_fusion	mitochondrial_dynamics:drp1_gtpase|mitochondrial_dynamics:fzo1_gtpase	chylomicron_assembly_secretion|egfr_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolism|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|urease_biogenesis_urea_hydrolysis	ACCEPT
worm/gcn-2	D0Z5N4	6239	GO:0009893	positive regulation of metabolic process	ARBA:ARBA00028097	NOT_ENTAILED	False	maternal_to_zygotic_transition			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	MARK_AS_OVER_ANNOTATED
worm/gcn-2	D0Z5N4	6239	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	c_elegans_mutator_22g_rna_amplification|maternal_to_zygotic_transition|pirna_mediated_germline_silencing|selenocysteine_biosynthesis_incorporation			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	ACCEPT
worm/gcn-2	D0Z5N4	6239	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	er_unfolded_protein_response|mitochondrial_upr|nrf_oxidative_stress_response		er_unfolded_protein_response:ire1_kinase|er_unfolded_protein_response:perk_eif2a_kinase|mitochondrial_upr:hri_eif2a_kinase|nrf_oxidative_stress_response:gsk3_kinase	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mito	ACCEPT
worm/gcn-2	D0Z5N4	6239	GO:0051246	regulation of protein metabolic process	ARBA:ARBA00028884	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	ACCEPT
worm/gcy-18	G5EFQ0	6239	GO:0016048	detection of temperature stimulus	ARBA:ARBA00087525	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-18	G5EFQ0	6239	GO:0040040	thermosensory behavior	ARBA:ARBA00086785	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-18	G5EFQ0	6239	GO:0043052	thermotaxis	ARBA:ARBA00084834	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-23	G5EEE9	6239	GO:0016048	detection of temperature stimulus	ARBA:ARBA00087525	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-23	G5EEE9	6239	GO:0040040	thermosensory behavior	ARBA:ARBA00086785	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-23	G5EEE9	6239	GO:0043052	thermotaxis	ARBA:ARBA00084834	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-33	P90895	6239	GO:0070482	response to oxygen levels	ARBA:ARBA00029157	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|mitochondrial_complex_ii|mitochondrial_upr	ACCEPT
worm/gcy-8	Q9GYQ4	6239	GO:0009266	response to temperature stimulus	ARBA:ARBA00026893	NOT_ENTAILED	False	heat_shock_response			c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/gcy-8	Q9GYQ4	6239	GO:0009581	detection of external stimulus	ARBA:ARBA00027562	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
worm/gcy-8	Q9GYQ4	6239	GO:0009582	detection of abiotic stimulus	ARBA:ARBA00027563	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
worm/gcy-8	Q9GYQ4	6239	GO:0042330	taxis	ARBA:ARBA00028791	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
worm/glh-1	P34689	6239	GO:0007281	germ cell development	ARBA:ARBA00028319	ENTAILED	True	c_elegans_p_granule_assembly_segregation|primordial_germ_cell_specification		c_elegans_p_granule_assembly_segregation:car1_rnp|c_elegans_p_granule_assembly_segregation:cgh1_helicase|c_elegans_p_granule_assembly_segregation:glh1_helicase|c_elegans_p_granule_assembly_segregation:glh2_helicase|c_elegans_p_granule_assembly_segregation:glh4_helicase|primordial_germ_cell_specification:germ_plasm_nanos|primordial_germ_cell_specification:germ_plasm_vasa	bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|metazoan_autophagosome_biogenesis|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_cata	ACCEPT
worm/glh-1	P34689	6239	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NOT_ENTAILED	False	c_elegans_daf2_insulin_signaling			bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|metazoan_autophagosome_biogenesis|methylcitrate_cycle|muth_independent_mismatch_repai	KEEP_AS_NON_CORE
worm/glh-2	Q966L9	6239	GO:0007281	germ cell development	ARBA:ARBA00028319	ENTAILED	True	c_elegans_p_granule_assembly_segregation|primordial_germ_cell_specification		c_elegans_p_granule_assembly_segregation:car1_rnp|c_elegans_p_granule_assembly_segregation:cgh1_helicase|c_elegans_p_granule_assembly_segregation:glh1_helicase|c_elegans_p_granule_assembly_segregation:glh2_helicase|c_elegans_p_granule_assembly_segregation:glh4_helicase|primordial_germ_cell_specification:germ_plasm_nanos|primordial_germ_cell_specification:germ_plasm_vasa	bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|metazoan_autophagosome_biogenesis|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_cata	ACCEPT
worm/glh-2	Q966L9	6239	GO:0009791	post-embryonic development	ARBA:ARBA00029007	NOT_ENTAILED	False	c_elegans_daf2_insulin_signaling			bacterial_nucleotide_excision_repair|c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|coenzyme_q10_biosynthesis|early_metazoan_development|linc_complex|maternal_to_zygotic_transition|metazoan_autophagosome_biogenesis|methylcitrate_cycle|muth_independent_mismatch_repai	KEEP_AS_NON_CORE
worm/glp-1	P13508	6239	GO:0001708	cell fate specification	ARBA:ARBA00089615	NOT_ENTAILED	False	cardiac_specification_network			c_elegans_jak_independent_stat_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	ACCEPT
worm/glp-1	P13508	6239	GO:0022611	dormancy process	ARBA:ARBA00091893	NO_MODULE	False				c_elegans_jak_independent_stat_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
worm/glp-1	P13508	6239	GO:0040024	dauer larval development	ARBA:ARBA00086745	NOT_ENTAILED	True	c_elegans_daf2_insulin_signaling			c_elegans_jak_independent_stat_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
worm/glp-1	P13508	6239	GO:0048589	developmental growth	ARBA:ARBA00044390	NO_MODULE	False				c_elegans_jak_independent_stat_signaling|gpcr_plc_calcium_pkc_signaling|mitochondrial_upr|notch_signaling|retinal_determination_network|wnt_signaling	KEEP_AS_NON_CORE
worm/hsp-1	P09446	6239	GO:0009408	response to heat	ARBA:ARBA00028092	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_e	ACCEPT
worm/hsp-110	Q05036	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:bag_nef|heat_shock_response:hsp110_nef	coenzyme_q10_biosynthesis|linc_complex|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
worm/hsp-16.1	P34696	6239	GO:0009408	response to heat	ARBA:ARBA00028092	NOT_ENTAILED	False	heat_shock_response			cobalamin_intracellular_processing|hedgehog_signaling	ACCEPT
worm/hsp-16.2	P06582	6239	GO:0009408	response to heat	ARBA:ARBA00028092	NOT_ENTAILED	False	heat_shock_response				ACCEPT
worm/hsp-16.48	P02513	6239	GO:0009408	response to heat	ARBA:ARBA00028092	NOT_ENTAILED	False	heat_shock_response			cobalamin_intracellular_processing|hedgehog_signaling	ACCEPT
worm/hsp-3	P27420	6239	GO:0030968	endoplasmic reticulum unfolded protein response	ARBA:ARBA00087847	NOT_ENTAILED	True	er_unfolded_protein_response			bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosi	ACCEPT
worm/hsp-4	P20163	6239	GO:0030968	endoplasmic reticulum unfolded protein response	ARBA:ARBA00087847	NOT_ENTAILED	True	er_unfolded_protein_response			bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosi	ACCEPT
worm/hsp-6	P11141	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
worm/hsp-70	O45246	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/ift-81	A8DYR7	6239	GO:0007018	microtubule-based movement	ARBA:ARBA00033543	ENTAILED	False	nucleokinesis		nucleokinesis:dcx_perinuclear_microtubule_stabilizer	ciliary_transition_zone	ACCEPT
worm/ire-1	Q09499	6239	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	pirna_mediated_germline_silencing		pirna_mediated_germline_silencing:ago3_slicer|pirna_mediated_germline_silencing:aub_slicer|pirna_mediated_germline_silencing:piwil2_slicer	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	ACCEPT
worm/ire-1	Q09499	6239	GO:0034976	response to endoplasmic reticulum stress	ARBA:ARBA00027479	ENTAILED	False	er_unfolded_protein_response		er_unfolded_protein_response:ire1_endoribonuclease|er_unfolded_protein_response:ire1_kinase	c_elegans_daf2_insulin_signaling|c_elegans_mutator_22g_rna_amplification|cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggl	ACCEPT
worm/ire-1	Q09499	6239	GO:0080090	regulation of primary metabolic process	ARBA:ARBA00026284	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			c_elegans_daf2_insulin_signaling|c_elegans_mutator_22g_rna_amplification|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_trans	MARK_AS_OVER_ANNOTATED
worm/let-23	P24348	6239	GO:0038127	ERBB signaling pathway	ARBA:ARBA00034175	ENTAILED	False	egfr_signaling		egfr_signaling:erbb2_coreceptor_kinase|egfr_signaling:fly_egfr_receptor|egfr_signaling:human_egfr_receptor|egfr_signaling:worm_let23_receptor	c_elegans_daf2_insulin_signaling|coenzyme_a_biosynthesis|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|notch_signaling|peptidoglycan_recycling|phagocytic_engulfment|sphingolipid_de_novo_synthesis	MODIFY
worm/lgg-2	Q23536	6239	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity			ciliary_transition_zone|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|synaptic_vesicle_endocytosis	ACCEPT
worm/lgg-2	Q23536	6239	GO:0016236	macroautophagy	ARBA:ARBA00027245	ENTAILED	True	metazoan_autophagosome_biogenesis		metazoan_autophagosome_biogenesis:gabarap_fusion|metazoan_autophagosome_biogenesis:lc3_elongation|metazoan_autophagosome_biogenesis:lgg1_early|metazoan_autophagosome_biogenesis:lgg2_late	ciliary_transition_zone|nucleokinesis|synaptic_vesicle_endocytosis	ACCEPT
worm/lin-12	P14585	6239	GO:0001708	cell fate specification	ARBA:ARBA00089615	NOT_ENTAILED	False	cardiac_specification_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	ACCEPT
worm/lin-12	P14585	6239	GO:0022611	dormancy process	ARBA:ARBA00091893	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
worm/lin-12	P14585	6239	GO:0040024	dauer larval development	ARBA:ARBA00086745	NOT_ENTAILED	True	c_elegans_daf2_insulin_signaling			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
worm/lin-12	P14585	6239	GO:0042659	regulation of cell fate specification	ARBA:ARBA00086800	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	ACCEPT
worm/lin-12	P14585	6239	GO:0045597	positive regulation of cell differentiation	ARBA:ARBA00028476	NO_MODULE	False				erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
worm/lin-12	P14585	6239	GO:0048513	animal organ development	ARBA:ARBA00029247	NOT_ENTAILED	False	cardiac_specification_network|nucleokinesis|retinal_determination_network			erbb2_signaling|gpcr_plc_calcium_pkc_signaling|notch_signaling|wnt_signaling	KEEP_AS_NON_CORE
worm/lis-1	Q9NDC9	6239	GO:0006909	phagocytosis	ARBA:ARBA00027650	NOT_ENTAILED	False	phagocytic_engulfment			complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
worm/lis-1	Q9NDC9	6239	GO:0007154	cell communication	ARBA:ARBA00028945	NOT_ENTAILED	False	c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling			complex_i_assembly_factors	REMOVE
worm/lis-1	Q9NDC9	6239	GO:0023052	signaling	ARBA:ARBA00026303	NOT_ENTAILED	False	c_elegans_core_apoptosis|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling			complex_i_assembly_factors	REMOVE
worm/lis-1	Q9NDC9	6239	GO:0051225	spindle assembly	ARBA:ARBA00089339	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
worm/lis-1	Q9NDC9	6239	GO:0051299	centrosome separation	ARBA:ARBA00089326	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
worm/lrx-1	Q22179	6239	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	NOT_ENTAILED	False	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis|snare_fusion_cycle|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis				REMOVE
worm/lys-1	O62415	6239	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity			phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
worm/lys-7	O16202	6239	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity			phenylacetate_catabolism	ACCEPT
worm/mek-2	Q10664	6239	GO:0000165	MAPK cascade	ARBA:ARBA00029221	ENTAILED	True	c_elegans_pmk1_intestinal_immunity|erk5_cascade|jnk_cascade|mapk_relay|p38_cascade		c_elegans_pmk1_intestinal_immunity:sek1_map2k|erk5_cascade:erk5_map2k_activity|jnk_cascade:jnk_map2k_activity|mapk_relay:map2k_activity|p38_cascade:p38_map2k_activity	c_elegans_p_granule_assembly_segregation|coenzyme_a_biosynthesis|egfr_signaling|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|nrf_oxidative_stress_response|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
worm/mek-2	Q10664	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	c_elegans_pmk1_intestinal_immunity|jnk_cascade|nrf_oxidative_stress_response|p38_cascade		c_elegans_pmk1_intestinal_immunity:sek1_map2k|jnk_cascade:jnk_map2k_activity|nrf_oxidative_stress_response:sek1_map2k|p38_cascade:p38_map2k_activity	c_elegans_p_granule_assembly_segregation|coenzyme_a_biosynthesis|egfr_signaling|erk5_cascade|g2_m_transition|integrin_fak_src_signaling|kinase_phosphatase_toggle|mapk_relay|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	REMOVE
worm/odr-1	B1Q257	6239	GO:0007635	chemosensory behavior	ARBA:ARBA00027929	NO_MODULE	False				c_elegans_cgmp_sensory_transduction	KEEP_AS_NON_CORE
worm/odr-1	B1Q257	6239	GO:0050913	sensory perception of bitter taste	ARBA:ARBA00091293	NO_MODULE	False				c_elegans_cgmp_sensory_transduction	KEEP_AS_NON_CORE
worm/odr-3	Q18434	6239	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity			c_elegans_cgmp_sensory_transduction|chylomicron_assembly_secretion|complex_i_assembly_factors|egfr_signaling|erbb2_signaling|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phagocytic_engulfment|phagosome_maturation|phenylacetate_catabolism|propionyl_coa_catabolis	MARK_AS_OVER_ANNOTATED
worm/osm-1	Q22830	6239	GO:0044782	cilium organization	ARBA:ARBA00027540	NOT_ENTAILED	False	ciliary_transition_zone|intraflagellar_transport				ACCEPT
worm/pdk-1	Q9Y1J3	6239	GO:0048638	regulation of developmental growth	ARBA:ARBA00091468	NOT_ENTAILED	False	c_elegans_dbl1_body_size_signaling			c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	MARK_AS_OVER_ANNOTATED
worm/pdk-1	Q9Y1J3	6239	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	nucleokinesis		nucleokinesis:cdk5_p35_kinase	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_	MARK_AS_OVER_ANNOTATED
worm/pdk-1	Q9Y1J3	6239	GO:1901701	cellular response to oxygen-containing compound	ARBA:ARBA00027483	ENTAILED	False	insulin_receptor_signaling		insulin_receptor_signaling:akt_effector	cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome	MARK_AS_OVER_ANNOTATED
worm/pdr-1	Q9XUS3	6239	GO:0009893	positive regulation of metabolic process	ARBA:ARBA00028097	NOT_ENTAILED	False	maternal_to_zygotic_transition			alginate_o_acetylation|cell_cycle_progression|fgfr_signaling|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitophagy|notch_signaling|peroxisome-lifecycle|toll_like_receptor_signaling|ubiquitin_transfer_relay|wnt_signaling	MARK_AS_OVER_ANNOTATED
worm/pek-1	Q19192	6239	GO:0034976	response to endoplasmic reticulum stress	ARBA:ARBA00027479	ENTAILED	False	er_unfolded_protein_response		er_unfolded_protein_response:ire1_kinase|er_unfolded_protein_response:perk_eif2a_kinase	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mito	ACCEPT
worm/phb-1	Q9BKU4	6239	GO:0002082	regulation of oxidative phosphorylation	ARBA:ARBA00088025	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	NOT_ENTAILED	False	nrf_oxidative_stress_response				KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0007283	spermatogenesis	ARBA:ARBA00085131	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0008406	gonad development	ARBA:ARBA00028782	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0030421	defecation	ARBA:ARBA00087140	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0040018	positive regulation of multicellular organism growth	ARBA:ARBA00086734	NOT_ENTAILED	True	c_elegans_dbl1_body_size_signaling				KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0043051	regulation of nematode pharyngeal pumping	ARBA:ARBA00084837	NO_MODULE	False					KEEP_AS_NON_CORE
worm/phb-1	Q9BKU4	6239	GO:0048477	oogenesis	ARBA:ARBA00028681	NOT_ENTAILED	False	c_elegans_p_granule_assembly_segregation				KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0002082	regulation of oxidative phosphorylation	ARBA:ARBA00088025	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0006979	response to oxidative stress	ARBA:ARBA00026273	NOT_ENTAILED	False	nrf_oxidative_stress_response			c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0007283	spermatogenesis	ARBA:ARBA00085131	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0008406	gonad development	ARBA:ARBA00028782	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0009792	embryo development ending in birth or egg hatching	ARBA:ARBA00029005	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0030421	defecation	ARBA:ARBA00087140	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0040018	positive regulation of multicellular organism growth	ARBA:ARBA00086734	NOT_ENTAILED	True	c_elegans_dbl1_body_size_signaling			c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0043051	regulation of nematode pharyngeal pumping	ARBA:ARBA00084837	NO_MODULE	False				c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/phb-2	P50093	6239	GO:0048477	oogenesis	ARBA:ARBA00028681	ENTAILED	False	c_elegans_p_granule_assembly_segregation		c_elegans_p_granule_assembly_segregation:pgl1_scaffold	heat_shock_response	KEEP_AS_NON_CORE
worm/pink-1	Q09298	6239	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	er_unfolded_protein_response|nrf_oxidative_stress_response		er_unfolded_protein_response:ire1_kinase|nrf_oxidative_stress_response:gsk3_kinase	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mito	ACCEPT
worm/pmk-1	Q17446	6239	GO:0000302	response to reactive oxygen species	ARBA:ARBA00027603	NO_MODULE	False				c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	ACCEPT
worm/pmk-1	Q17446	6239	GO:0006955	immune response	ARBA:ARBA00026313	ENTAILED	False	c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity		c_elegans_jak_independent_stat_signaling:pmk1_p38_input|c_elegans_pmk1_intestinal_immunity:pmk1_p38	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|jnk_cas	ACCEPT
worm/pmk-1	Q17446	6239	GO:0006970	response to osmotic stress	ARBA:ARBA00026252	NO_MODULE	False				c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	ACCEPT
worm/pmk-1	Q17446	6239	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	c_elegans_pmk1_intestinal_immunity|egfr_signaling|er_unfolded_protein_response|erk5_cascade|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hippo_signaling|insulin_receptor_signaling|jnk_cascade|mapk_relay|nlr_signaling|p38_cascade|tnf_signaling|toll_like_receptor_signaling|wnt_signaling		c_elegans_pmk1_intestinal_immunity:pmk1_p38|egfr_signaling:erk_mapk|er_unfolded_protein_response:ire1_kinase|erk5_cascade:erk5_mapk_activity|erk5_cascade:erk5_substrate_output|gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c|hippo_signaling:lats_kinase|hippo_signaling:mst_kinase|insulin_receptor_signaling:akt_effector|jnk_cascade:jnk_mapk_activity|jnk_cascade:jnk_substrate_output|mapk_relay:mapk_activity|nlr_signaling:tak1_complex_ikkbeta_kinase|p38_cascade:p38_mapk_activity|p38_cascade:p38_substrate_output|tnf_signaling:tak1_complex_ikkbeta_kinase|toll_like_receptor_signaling:irak4_kinase|toll_like_receptor_signaling:tak1_kinase|wnt_signaling:beta_catenin|wnt_signaling:destruction_complex	c_elegans_jak_independent_stat_signaling|coenzyme_a_biosynthesis|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nrf_oxidative_stress_response|nucleokinesis|peptidoglycan_recycling|sphingoli	ACCEPT
worm/pmk-1	Q17446	6239	GO:0009408	response to heat	ARBA:ARBA00028092	NOT_ENTAILED	False	heat_shock_response			c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	KEEP_AS_NON_CORE
worm/pmk-1	Q17446	6239	GO:0042742	defense response to bacterium	ARBA:ARBA00028625	ENTAILED	False	c_elegans_pmk1_intestinal_immunity		c_elegans_pmk1_intestinal_immunity:pmk1_p38	c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_s	ACCEPT
worm/pmk-1	Q17446	6239	GO:0050832	defense response to fungus	ARBA:ARBA00029244	NO_MODULE	False				c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	ACCEPT
worm/pmk-1	Q17446	6239	GO:0071248	cellular response to metal ion	ARBA:ARBA00028718	NO_MODULE	False				c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	KEEP_AS_NON_CORE
worm/pmk-1	Q17446	6239	GO:0080135	regulation of cellular response to stress	ARBA:ARBA00026867	NO_MODULE	False				c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling	ACCEPT
worm/prg-1	P90786	6239	GO:0007279	pole cell formation	ARBA:ARBA00085029	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|er_unfolded_protein_response|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	REMOVE
worm/prg-1	P90786	6239	GO:0009994	oocyte differentiation	ARBA:ARBA00084567	NOT_ENTAILED	False	c_elegans_p_granule_assembly_segregation			c_elegans_mutator_22g_rna_amplification|er_unfolded_protein_response|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	KEEP_AS_NON_CORE
worm/prg-1	P90786	6239	GO:0010526	transposable element silencing	ARBA:ARBA00092295	ENTAILED	True	pirna_mediated_germline_silencing		pirna_mediated_germline_silencing:ago3_slicer|pirna_mediated_germline_silencing:aub_slicer|pirna_mediated_germline_silencing:fly_piwi_nuclear|pirna_mediated_germline_silencing:piwi_pirna_guide|pirna_mediated_germline_silencing:piwil2_slicer|pirna_mediated_germline_silencing:piwil4_nuclear	c_elegans_mutator_22g_rna_amplification|er_unfolded_protein_response|phenylacetate_catabolism|primordial_germ_cell_specification	ACCEPT
worm/prg-1	P90786	6239	GO:0034587	piRNA processing	ARBA:ARBA00047257	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|er_unfolded_protein_response|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	UNDECIDED
worm/prg-1	P90786	6239	GO:0140991	piRNA-mediated gene silencing by mRNA destabilization	ARBA:ARBA00087016	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|er_unfolded_protein_response|phenylacetate_catabolism|pirna_mediated_germline_silencing|primordial_germ_cell_specification	MODIFY
worm/ric-4	A5PEW5	6239	GO:0006887	exocytosis	ARBA:ARBA00027178	MODULE_INCOMPLETE	False	synaptic_vesicle_exocytosis	synaptic_vesicle_exocytosis:presynaptic_calcium_influx	synaptic_vesicle_exocytosis:complexin_clamp|synaptic_vesicle_exocytosis:synaptic_snare_complex	c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|	ACCEPT
worm/sdf-9	G5EGA9	6239	GO:0040024	dauer larval development	ARBA:ARBA00086745	NOT_ENTAILED	True	c_elegans_daf2_insulin_signaling				ACCEPT
worm/sek-1	G5EDF7	6239	GO:0000165	MAPK cascade	ARBA:ARBA00029221	ENTAILED	True	c_elegans_pmk1_intestinal_immunity|erk5_cascade|jnk_cascade|mapk_relay|p38_cascade		c_elegans_pmk1_intestinal_immunity:sek1_map2k|erk5_cascade:erk5_map2k_activity|jnk_cascade:jnk_map2k_activity|mapk_relay:map2k_activity|p38_cascade:p38_map2k_activity	c_elegans_daf2_insulin_signaling|c_elegans_p_granule_assembly_segregation|cgas_sting_signaling|coenzyme_a_biosynthesis|egfr_signaling|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|inte	ACCEPT
worm/sem-5	P29355	6239	GO:0007173	epidermal growth factor receptor signaling pathway	ARBA:ARBA00034174	ENTAILED	True	egfr_signaling		egfr_signaling:grb2_drk_sem5_adaptor	erbb2_signaling|phosphotyrosine_adaptor_recruitment	ACCEPT
worm/skn-1	P34707	6239	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	ENTAILED	False	maternal_to_zygotic_transition		maternal_to_zygotic_transition:zga_activator|maternal_to_zygotic_transition:zga_pluripotency_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	ACCEPT
worm/sma-2	Q02330	6239	GO:0009791	post-embryonic development	ARBA:ARBA00029007	MODULE_INCOMPLETE	False	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:daf16_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|ear	KEEP_AS_NON_CORE
worm/sma-2	Q02330	6239	GO:0050793	regulation of developmental process	ARBA:ARBA00028689	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	KEEP_AS_NON_CORE
worm/sma-2	Q02330	6239	GO:0051239	regulation of multicellular organismal process	ARBA:ARBA00028859	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	KEEP_AS_NON_CORE
worm/sma-2	Q02330	6239	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cgas_sting_signaling|early_metazoan_development|er_unf	KEEP_AS_NON_CORE
worm/sma-3	P45896	6239	GO:0009791	post-embryonic development	ARBA:ARBA00029007	MODULE_INCOMPLETE	False	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:daf16_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|ear	KEEP_AS_NON_CORE
worm/sma-3	P45896	6239	GO:0045595	regulation of cell differentiation	ARBA:ARBA00028479	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	KEEP_AS_NON_CORE
worm/sma-3	P45896	6239	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	ACCEPT
worm/sma-3	P45896	6239	GO:0048639	positive regulation of developmental growth	ARBA:ARBA00091477	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	ACCEPT
worm/sma-3	P45896	6239	GO:0048731	system development	ARBA:ARBA00027702	ENTAILED	False	cardiac_specification_network|retinal_determination_network		cardiac_specification_network:gata_tf|cardiac_specification_network:hand_tf|cardiac_specification_network:mef2_tf|cardiac_specification_network:nk2_tf|cardiac_specification_network:tbox_tf|retinal_determination_network:dach_coregulator|retinal_determination_network:eya_coactivator|retinal_determination_network:pax6_tf|retinal_determination_network:six_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cgas_sting_signaling|	KEEP_AS_NON_CORE
worm/sma-3	P45896	6239	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	KEEP_AS_NON_CORE
worm/sma-3	P45896	6239	GO:0090066	regulation of anatomical structure size	ARBA:ARBA00029178	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	ACCEPT
worm/sma-3	P45896	6239	GO:0090596	sensory organ morphogenesis	ARBA:ARBA00043576	NO_MODULE	False				bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification	KEEP_AS_NON_CORE
worm/sma-4	P45897	6239	GO:0008340	determination of adult lifespan	ARBA:ARBA00026742	ENTAILED	True	c_elegans_lysosomal_lipid_signaling		c_elegans_lysosomal_lipid_signaling:hlh30_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early_metazoan_development|er_unfolded_	UNDECIDED
worm/sma-4	P45897	6239	GO:0040024	dauer larval development	ARBA:ARBA00086745	MODULE_INCOMPLETE	True	c_elegans_daf2_insulin_signaling	c_elegans_daf2_insulin_signaling:age1_pi3k|c_elegans_daf2_insulin_signaling:pdk1_step	c_elegans_daf2_insulin_signaling:daf16_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|ear	UNDECIDED
worm/sma-4	P45897	6239	GO:0048639	positive regulation of developmental growth	ARBA:ARBA00091477	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	ACCEPT
worm/sma-4	P45897	6239	GO:0051240	positive regulation of multicellular organismal process	ARBA:ARBA00028891	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	KEEP_AS_NON_CORE
worm/sma-9	Q7JM44	6239	GO:0071363	cellular response to growth factor stimulus	ARBA:ARBA00027976	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad|c_elegans_dbl1_body_size_signaling:sma9_corepressor	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	KEEP_AS_NON_CORE
worm/sma-9	Q7JM44	6239	GO:0141091	transforming growth factor beta receptor superfamily signaling pathway	ARBA:ARBA00043534	MODULE_INCOMPLETE	False	c_elegans_dbl1_body_size_signaling	c_elegans_dbl1_body_size_signaling:receptor_pair	c_elegans_dbl1_body_size_signaling:sma2_smad|c_elegans_dbl1_body_size_signaling:sma3_smad|c_elegans_dbl1_body_size_signaling:sma4_cosmad|c_elegans_dbl1_body_size_signaling:sma9_corepressor	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|c_elegans_translation_surveillance_immunity|cardiac_specification_network|cgas_sting_signaling|early	ACCEPT
worm/snb-1	O02495	6239	GO:0016079	synaptic vesicle exocytosis	ARBA:ARBA00028976	MODULE_INCOMPLETE	True	synaptic_vesicle_exocytosis	synaptic_vesicle_exocytosis:presynaptic_calcium_influx	synaptic_vesicle_exocytosis:complexin_clamp|synaptic_vesicle_exocytosis:synaptic_snare_complex	c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|	ACCEPT
worm/snt-1	P34693	6239	GO:0007626	locomotory behavior	ARBA:ARBA00086008	NO_MODULE	False				gpcr_plc_calcium_pkc_signaling|synaptic_vesicle_cycle|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
worm/snt-1	P34693	6239	GO:0048488	synaptic vesicle endocytosis	ARBA:ARBA00091614	ENTAILED	True	synaptic_vesicle_endocytosis		synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	gpcr_plc_calcium_pkc_signaling|synaptic_vesicle_cycle|synaptic_vesicle_exocytosis	ACCEPT
worm/spg-7	Q9N3T5	6239	GO:0051604	protein maturation	ARBA:ARBA00026902	ENTAILED	False	protease_activation_cascade		protease_activation_cascade:effector_activity|protease_activation_cascade:initiator_activity	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|hedgehog_signaling|linc_complex|mitochondrial_upr|muth_independent_mismatch_repair|notch_signaling|peroxisome-lifecycle|phenylacetate_catabolism|synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/tax-4	Q03611	6239	GO:0070482	response to oxygen levels	ARBA:ARBA00029157	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|c_elegans_p_granule_assembly_segregation|heat_shock_response	KEEP_AS_NON_CORE
worm/tir-1	Q86DA5	6239	GO:0019677	NAD+ catabolic process	ARBA:ARBA00028167	NO_MODULE	False				c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|c_elegans_pmk1_intestinal_immunity|cgas_sting_signaling|ciliary_transition_zone|egfr_signaling|heat_shock_response|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mito	ACCEPT
worm/ufd-1	Q19584	6239	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				complex_i_assembly_factors	ACCEPT
worm/unc-11	Q9XZI6	6239	GO:0006898	receptor-mediated endocytosis	ARBA:ARBA00044584	NOT_ENTAILED	True	cobalamin_absorption_transport|ldl_receptor_mediated_endocytosis			synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	ACCEPT
worm/unc-11	Q9XZI6	6239	GO:0040011	locomotion	ARBA:ARBA00026452	NO_MODULE	False				synaptic_vesicle_endocytosis|synaptic_vesicle_exocytosis	KEEP_AS_NON_CORE
worm/unc-11	Q9XZI6	6239	GO:0048488	synaptic vesicle endocytosis	ARBA:ARBA00091614	ENTAILED	True	synaptic_vesicle_endocytosis		synaptic_vesicle_endocytosis:amphiphysin_bar_protein|synaptic_vesicle_endocytosis:ap180_assembly_protein|synaptic_vesicle_endocytosis:auxilin_cochaperone|synaptic_vesicle_endocytosis:endophilin_a_bar_protein|synaptic_vesicle_endocytosis:syndapin_fbar_protein	synaptic_vesicle_exocytosis	ACCEPT
worm/unc-18	P34815	6239	GO:0006887	exocytosis	ARBA:ARBA00027178	MODULE_INCOMPLETE	False	synaptic_vesicle_exocytosis	synaptic_vesicle_exocytosis:presynaptic_calcium_influx	synaptic_vesicle_exocytosis:complexin_clamp		ACCEPT
worm/unc-18	P34815	6239	GO:0051650	establishment of vesicle localization	ARBA:ARBA00033964	NO_MODULE	False				synaptic_vesicle_exocytosis	ACCEPT
worm/unc-2	G5EFB0	6239	GO:0009581	detection of external stimulus	ARBA:ARBA00027562	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
worm/unc-2	G5EFB0	6239	GO:0009582	detection of abiotic stimulus	ARBA:ARBA00027563	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
worm/unc-2	G5EFB0	6239	GO:0016322	neuron remodeling	ARBA:ARBA00086716	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
worm/unc-2	G5EFB0	6239	GO:0019722	calcium-mediated signaling	ARBA:ARBA00027115	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|gpcr_plc_calcium_pkc_signaling	ACCEPT
worm/unc-2	G5EFB0	6239	GO:0042045	epithelial fluid transport	ARBA:ARBA00086211	NO_MODULE	False				c_elegans_cgmp_sensory_transduction|gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
worm/unc-2	G5EFB0	6239	GO:0050906	detection of stimulus involved in sensory perception	ARBA:ARBA00028231	ENTAILED	True	c_elegans_cgmp_sensory_transduction		c_elegans_cgmp_sensory_transduction:tax2_beta	gpcr_plc_calcium_pkc_signaling	MARK_AS_OVER_ANNOTATED
worm/unc-51	Q23023	6239	GO:0006914	autophagy	ARBA:ARBA00027757	ENTAILED	False	metazoan_autophagosome_biogenesis		metazoan_autophagosome_biogenesis:ulk_kinase	c_elegans_daf2_insulin_signaling|cgas_sting_signaling|coenzyme_a_biosynthesis|er_unfolded_protein_response|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|hedgehog_signaling|hippo_signaling|insulin_receptor_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase	ACCEPT
worm/unc-57	B1V8A0	6239	GO:0016192	vesicle-mediated transport	ARBA:ARBA00028249	ENTAILED	False	vesicle_coat_budding		vesicle_coat_budding:cargo_adaptor_activity	c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitophagy|nucleokinesis|oligosaccharyltransferase_complex|phagocytic_engulfment|	ACCEPT
worm/unc-64	O16000	6239	GO:0007269	neurotransmitter secretion	ARBA:ARBA00028186	MODULE_INCOMPLETE	False	synaptic_vesicle_exocytosis	synaptic_vesicle_exocytosis:presynaptic_calcium_influx	synaptic_vesicle_exocytosis:complexin_clamp|synaptic_vesicle_exocytosis:synaptic_snare_complex	c_elegans_mutator_22g_rna_amplification|c_elegans_p_granule_assembly_segregation|ciliary_transition_zone|egfr_signaling|hedgehog_signaling|metaphase_anaphase_transition_and_mitotic_exit|metazoan_autophagosome_biogenesis|mitochondrial_complex_ii|mitophagy|nucleokinesis|oligosaccharyltransferase_compl	ACCEPT
worm/vha-1	Q21898	6239	GO:0007042	lysosomal lumen acidification	ARBA:ARBA00092063	NO_MODULE	False				mitochondrial_complex_v|phagosome_maturation|synaptic_vesicle_cycle|synaptic_vesicle_neurotransmitter_loading	ACCEPT
worm/vps-34	Q9TXI7	6239	GO:0160108	animal gross anatomical part developmental process	ARBA:ARBA00098139	NOT_ENTAILED	False	c_elegans_daf2_insulin_signaling|cardiac_specification_network|nucleokinesis|retinal_determination_network			coenzyme_a_biosynthesis|metazoan_autophagosome_biogenesis|peptidoglycan_recycling|phagosome_maturation|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
worm/zip-2	Q21148	6239	GO:0050829	defense response to Gram-negative bacterium	ARBA:ARBA00029238	ENTAILED	True	c_elegans_translation_surveillance_immunity		c_elegans_translation_surveillance_immunity:cebp2_tf|c_elegans_translation_surveillance_immunity:zip2_tf	bacterial_recbcd_end_resection|body_axis_specification|c_elegans_daf2_insulin_signaling|c_elegans_dbl1_body_size_signaling|c_elegans_jak_independent_stat_signaling|c_elegans_lysosomal_lipid_signaling|c_elegans_pmk1_intestinal_immunity|cardiac_specification_network|cgas_sting_signaling|early_metazoan	ACCEPT
yeast/ACC1	Q00955	559292	GO:0042759	long-chain fatty acid biosynthetic process	ARBA:ARBA00034980	NO_MODULE	False				bacterial_pyruvate_metabolism|fatty_acid_de_novo_synthesis|heat_shock_response|leucine_catabolism|type_ii_fatty_acid_synthesis	ACCEPT
yeast/ADE1	P27616	559292	GO:0009152	purine ribonucleotide biosynthetic process	ARBA:ARBA00027685	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purC_activity	coenzyme_a_biosynthesis	ACCEPT
yeast/ADE13	Q05911	559292	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	ARBA:ARBA00027608	ENTAILED	False	de_novo_purine_synthesis|purine_nucleotide_interconversion		de_novo_purine_synthesis:purB_saicar_activity|purine_nucleotide_interconversion:adsl_amp_activity		ACCEPT
yeast/ADE2	P21264	559292	GO:0006144	purine nucleobase metabolic process	ARBA:ARBA00084209	NOT_ENTAILED	True	purine_salvage_and_catabolism			de_novo_purine_synthesis|type_ii_fatty_acid_synthesis	MODIFY
yeast/ADE3	P07245	559292	GO:0006760	folic acid-containing compound metabolic process	ARBA:ARBA00027960	ENTAILED	False	folate_one_carbon_interconversion		folate_one_carbon_interconversion:bacterial_fold_nadp_methylene_methenyl_activity|folate_one_carbon_interconversion:cytosolic_c1thf_synthase_nadp_activity|folate_one_carbon_interconversion:cytosolic_mthfd1_nadp_methylene_methenyl_activity|folate_one_carbon_interconversion:fused_fold_mthfd_cyclohydrolase_activity|folate_one_carbon_interconversion:mitochondrial_c1thf_synthase_nadp_activity|folate_one_carbon_interconversion:monofunctional_fcha_cyclohydrolase_activity|folate_one_carbon_interconversion:monofunctional_mtda_nadp_methylene_methenyl_activity	complex_i_assembly_factors|hydroxyproline_catabolism|phenylacetate_catabolism	ACCEPT
yeast/ADE3	P07245	559292	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|coenzyme_a_biosynthesis|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			complex_i_assembly_factors|folate_one_carbon_interconversion|hydroxyproline_catabolism|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
yeast/ADE3	P07245	559292	GO:0072522	purine-containing compound biosynthetic process	ARBA:ARBA00026861	NOT_ENTAILED	False	coenzyme_a_biosynthesis|de_novo_purine_synthesis|fatty_acid_de_novo_synthesis|kynurenine_nad_de_novo|mitochondrial_complex_v			complex_i_assembly_factors|folate_one_carbon_interconversion|hydroxyproline_catabolism|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/ADE57	P07244	559292	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purD_activity|de_novo_purine_synthesis:purM_activity		MARK_AS_OVER_ANNOTATED
yeast/ADE57	P07244	559292	GO:0072521	purine-containing compound metabolic process	ARBA:ARBA00026860	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purD_activity|de_novo_purine_synthesis:purM_activity		MARK_AS_OVER_ANNOTATED
yeast/ADE6	P38972	559292	GO:0006164	purine nucleotide biosynthetic process	ARBA:ARBA00026733	ENTAILED	False	de_novo_purine_synthesis		de_novo_purine_synthesis:purL_activity		ACCEPT
yeast/ADH1	P00330	559292	GO:0006552	L-leucine catabolic process	ARBA:ARBA00085529	NOT_ENTAILED	True	leucine_catabolism			complex_i_assembly_factors|ehrlich_pathway|heat_shock_response	ACCEPT
yeast/ADH2	P00331	559292	GO:0006552	L-leucine catabolic process	ARBA:ARBA00085529	NOT_ENTAILED	True	leucine_catabolism			complex_i_assembly_factors|ehrlich_pathway	ACCEPT
yeast/ADH3	P07246	559292	GO:0006552	L-leucine catabolic process	ARBA:ARBA00085529	NOT_ENTAILED	True	leucine_catabolism			complex_i_assembly_factors|ehrlich_pathway	ACCEPT
yeast/ADH4	P10127	559292	GO:0046395	carboxylic acid catabolic process	ARBA:ARBA00027882	ENTAILED	False	ehrlich_pathway		ehrlich_pathway:adh_fusel_alcohol_formation	complex_i_assembly_factors	MARK_AS_OVER_ANNOTATED
yeast/ADH5	P38113	559292	GO:0006552	L-leucine catabolic process	ARBA:ARBA00085529	NOT_ENTAILED	True	leucine_catabolism			complex_i_assembly_factors|ehrlich_pathway	ACCEPT
yeast/ADK1	P07170	559292	GO:0009117	nucleotide metabolic process	ARBA:ARBA00027584	ENTAILED	False	purine_nucleotide_interconversion		purine_nucleotide_interconversion:adenylate_kinase_activity	bacterial_recbcd_end_resection|coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/ADO1	P47143	559292	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	ENTAILED	False	coenzyme_a_biosynthesis|purine_salvage_and_catabolism		coenzyme_a_biosynthesis:pok_activity|purine_salvage_and_catabolism:adenosine_kinase_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/ADO1	P47143	559292	GO:0072522	purine-containing compound biosynthetic process	ARBA:ARBA00026861	ENTAILED	False	coenzyme_a_biosynthesis|purine_salvage_and_catabolism		coenzyme_a_biosynthesis:pok_activity|purine_salvage_and_catabolism:adenosine_kinase_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/ADO1	P47143	559292	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	NOT_ENTAILED	False	adp_heptose_biosynthesis|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis|dntp_de_novo_synthesis			coenzyme_a_biosynthesis|peptidoglycan_recycling|purine_salvage_and_catabolism|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
yeast/ALD2	P47771	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	coenzyme_a_biosynthesis		coenzyme_a_biosynthesis:ald2_ald3_aminopropanal_dehydrogenase_activity	complex_i_assembly_factors|ehrlich_pathway|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/ALD3	P54114	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	coenzyme_a_biosynthesis		coenzyme_a_biosynthesis:ald2_ald3_aminopropanal_dehydrogenase_activity	complex_i_assembly_factors|ehrlich_pathway|gamma_glutamyl_putrescine_catabolism|glucarate_galactarate_catabolism|phenylacetate_catabolism	MODIFY
yeast/ALO1	P54783	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors	KEEP_AS_NON_CORE
yeast/ARG5,6	Q01217	559292	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argB_activity|arginine_biosynthesis:argC1_activity|arginine_biosynthesis:argC2_activity	coenzyme_a_biosynthesis|complex_i_assembly_factors|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
yeast/ARG5,6	Q01217	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	arginine_biosynthesis|coenzyme_a_biosynthesis		arginine_biosynthesis:argB_activity|arginine_biosynthesis:argC1_activity|arginine_biosynthesis:argC2_activity|coenzyme_a_biosynthesis:pok_activity	complex_i_assembly_factors|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
yeast/ARG7	Q04728	559292	GO:0008652	amino acid biosynthetic process	ARBA:ARBA00027355	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argA_activity|arginine_biosynthesis:argJ_initiating_activity|arginine_biosynthesis:argJ_recycling_activity|arginine_biosynthesis:fungal_nags_activity	alginate_o_acetylation|urea_cycle	MODIFY
yeast/ARG7	Q04728	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	arginine_biosynthesis		arginine_biosynthesis:argA_activity|arginine_biosynthesis:argJ_initiating_activity|arginine_biosynthesis:argJ_recycling_activity|arginine_biosynthesis:fungal_nags_activity	alginate_o_acetylation|urea_cycle	MODIFY
yeast/ARO1	P08566	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	bacterial_shikimate_chorismate_biosynthesis|coenzyme_a_biosynthesis|methionine_biosynthesis		bacterial_shikimate_chorismate_biosynthesis:aroa_epsp_synthase|bacterial_shikimate_chorismate_biosynthesis:arob_dehydroquinate_synthase|bacterial_shikimate_chorismate_biosynthesis:aroe_shikimate_dehydrogenase|bacterial_shikimate_chorismate_biosynthesis:arok_shikimate_kinase|bacterial_shikimate_chorismate_biosynthesis:arom_dhqase|bacterial_shikimate_chorismate_biosynthesis:arom_dhqs|bacterial_shikimate_chorismate_biosynthesis:arom_epsps|bacterial_shikimate_chorismate_biosynthesis:arom_sdh|bacterial_shikimate_chorismate_biosynthesis:arom_sk|bacterial_shikimate_chorismate_biosynthesis:aroq_dehydroquinase|bacterial_shikimate_chorismate_biosynthesis:type_i_dehydroquinase|coenzyme_a_biosynthesis:pok_activity|methionine_biosynthesis:metZ_activity	complex_i_assembly_factors|methylcitrate_cycle|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
yeast/ARO10	Q06408	559292	GO:0006559	L-phenylalanine catabolic process	ARBA:ARBA00085541	NOT_ENTAILED	True	tyrosine_catabolism			ehrlich_pathway|type_ii_fatty_acid_synthesis	ACCEPT
yeast/ARO10	Q06408	559292	GO:0006569	L-tryptophan catabolic process	ARBA:ARBA00026552	NOT_ENTAILED	True	kynurenine_nad_de_novo			ehrlich_pathway|type_ii_fatty_acid_synthesis	ACCEPT
yeast/ARO7	P32178	559292	GO:0006571	L-tyrosine biosynthetic process	ARBA:ARBA00026432	ENTAILED	True	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:chorismate_mutase	methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
yeast/ARO7	P32178	559292	GO:0009094	L-phenylalanine biosynthetic process	ARBA:ARBA00091461	ENTAILED	True	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:chorismate_mutase	methylcitrate_cycle|phenylacetate_catabolism	ACCEPT
yeast/ASP1	P38986	559292	GO:0006530	L-asparagine catabolic process	ARBA:ARBA00026337	ENTAILED	True	aspartate_asparagine_metabolism		aspartate_asparagine_metabolism:cell_wall_asparaginase_activity|aspartate_asparagine_metabolism:intracellular_asparaginase_activity	phenylacetate_catabolism	ACCEPT
yeast/ASP3-1	P0CZ17	559292	GO:0006530	L-asparagine catabolic process	ARBA:ARBA00026337	ENTAILED	True	aspartate_asparagine_metabolism		aspartate_asparagine_metabolism:cell_wall_asparaginase_activity|aspartate_asparagine_metabolism:intracellular_asparaginase_activity	phenylacetate_catabolism	ACCEPT
yeast/ASP3-2	P0CX77	559292	GO:0006530	L-asparagine catabolic process	ARBA:ARBA00026337	ENTAILED	True	aspartate_asparagine_metabolism		aspartate_asparagine_metabolism:cell_wall_asparaginase_activity|aspartate_asparagine_metabolism:intracellular_asparaginase_activity	phenylacetate_catabolism	ACCEPT
yeast/ASP3-3	P0CX78	559292	GO:0006530	L-asparagine catabolic process	ARBA:ARBA00026337	ENTAILED	True	aspartate_asparagine_metabolism		aspartate_asparagine_metabolism:cell_wall_asparaginase_activity|aspartate_asparagine_metabolism:intracellular_asparaginase_activity	phenylacetate_catabolism	ACCEPT
yeast/ASP3-4	P0CX79	559292	GO:0006530	L-asparagine catabolic process	ARBA:ARBA00026337	ENTAILED	True	aspartate_asparagine_metabolism		aspartate_asparagine_metabolism:cell_wall_asparaginase_activity|aspartate_asparagine_metabolism:intracellular_asparaginase_activity	phenylacetate_catabolism	ACCEPT
yeast/ATG7	P38862	559292	GO:0016237	microautophagy	ARBA:ARBA00027243	NO_MODULE	False				heat_shock_response|thiamine_diphosphate_biosynthesis|ubiquitin_transfer_relay	MARK_AS_OVER_ANNOTATED
yeast/AUR1	P36107	559292	GO:0006629	lipid metabolic process	ARBA:ARBA00028591	ENTAILED	False	sphingolipid_de_novo_synthesis		sphingolipid_de_novo_synthesis:aur1_activity		ACCEPT
yeast/BAT1	P38891	559292	GO:0009082	branched-chain amino acid biosynthetic process	ARBA:ARBA00028438	ENTAILED	True	branched_chain_amino_acid_biosynthesis		branched_chain_amino_acid_biosynthesis:ilvE_activity	branched_chain_amino_acid_catabolism|ehrlich_pathway|methionine_salvage_mta_cycle|ubiquinone_biosynthesis	ACCEPT
yeast/BAT1	P38891	559292	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	ENTAILED	True	ehrlich_pathway		ehrlich_pathway:bat1_mitochondrial_transaminase|ehrlich_pathway:bat2_catabolic_transaminase	branched_chain_amino_acid_biosynthesis|methionine_salvage_mta_cycle|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
yeast/BAT2	P47176	559292	GO:0009082	branched-chain amino acid biosynthetic process	ARBA:ARBA00028438	ENTAILED	True	branched_chain_amino_acid_biosynthesis		branched_chain_amino_acid_biosynthesis:ilvE_activity	branched_chain_amino_acid_catabolism|ehrlich_pathway|methionine_salvage_mta_cycle|ubiquinone_biosynthesis	KEEP_AS_NON_CORE
yeast/BAT2	P47176	559292	GO:0009083	branched-chain amino acid catabolic process	ARBA:ARBA00091432	ENTAILED	True	ehrlich_pathway		ehrlich_pathway:bat1_mitochondrial_transaminase|ehrlich_pathway:bat2_catabolic_transaminase	branched_chain_amino_acid_biosynthesis|methionine_salvage_mta_cycle|ubiquinone_biosynthesis	ACCEPT
yeast/BTT1	P40314	559292	GO:0006613	cotranslational protein targeting to membrane	ARBA:ARBA00087310	NO_MODULE	False					ACCEPT
yeast/BUD16	P39988	559292	GO:0042364	water-soluble vitamin biosynthetic process	ARBA:ARBA00029043	ENTAILED	False	coenzyme_a_biosynthesis|vitamin_b6_plp_metabolism		coenzyme_a_biosynthesis:pok_activity|vitamin_b6_plp_metabolism:pdxk_activity	peptidoglycan_recycling|sphingolipid_de_novo_synthesis	MODIFY
yeast/CDC14	Q00684	559292	GO:0000278	mitotic cell cycle	ARBA:ARBA00028458	ENTAILED	False	g2_m_transition		g2_m_transition:cdc25_phosphatase|g2_m_transition:pp2a_b55	gpi_anchor_remodeling|kinase_phosphatase_toggle|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/CDC14	Q00684	559292	GO:0007096	regulation of exit from mitosis	ARBA:ARBA00092142	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/CDC14	Q00684	559292	GO:0032954	regulation of cytokinetic process	ARBA:ARBA00087459	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/CDC14	Q00684	559292	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/CDC20	P26309	559292	GO:0031145	anaphase-promoting complex-dependent catabolic process	ARBA:ARBA00034936	NO_MODULE	False				complex_i_assembly_factors|dolichol_phosphate_sugar_donor_supply|metaphase_anaphase_transition_and_mitotic_exit|sphingolipid_de_novo_synthesis	ACCEPT
yeast/CDC28	P00546	559292	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	ENTAILED	True	g1_s_transition		g1_s_transition:g1_cdk|g1_s_transition:g1s_cdk	cell_cycle_progression|coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/CDC28	P00546	559292	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				cell_cycle_progression|coenzyme_a_biosynthesis|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/CDC28	P00546	559292	GO:0010570	regulation of filamentous growth	ARBA:ARBA00027572	NO_MODULE	False				cell_cycle_progression|coenzyme_a_biosynthesis|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/CDC53	Q12018	559292	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ARBA:ARBA00084384	NO_MODULE	False				alginate_o_acetylation|bacterial_recbcd_end_resection|cell_cycle_progression|complex_i_accessory_subunits|ergosterol_biosynthesis|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial_complex_iii|mitochondrial_complex_iv|mitochondrial_complex_v|oli	ACCEPT
yeast/CDC55	Q00362	559292	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	ARBA:ARBA00084549	NO_MODULE	False				sphingolipid_de_novo_synthesis	MODIFY
yeast/CDC55	Q00362	559292	GO:1902531	regulation of intracellular signal transduction	ARBA:ARBA00027126	NO_MODULE	False				sphingolipid_de_novo_synthesis	MODIFY
yeast/CDC8	P00572	559292	GO:0006227	dUDP biosynthetic process	ARBA:ARBA00086376	NO_MODULE	False				coenzyme_a_biosynthesis|de_novo_pyrimidine_synthesis|dntp_de_novo_synthesis|purine_nucleotide_interconversion|sphingolipid_de_novo_synthesis|thymidylate_synthesis	KEEP_AS_NON_CORE
yeast/CDD1	Q06549	559292	GO:0055086	nucleobase-containing small molecule metabolic process	ARBA:ARBA00027681	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism	pyrimidine_nucleotide_catabolism:uridine_phosphorolysis|pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis|pyrimidine_nucleotide_catabolism:dihydropyrimidine_reduction|pyrimidine_nucleotide_catabolism:dihydropyrimidine_hydrolysis|pyrimidine_nucleotide_catabolism:ureidopropionase	pyrimidine_nucleotide_catabolism:cda_activity	heat_shock_response|phenylacetate_catabolism|pyrimidine_salvage	MODIFY
yeast/CDD1	Q06549	559292	GO:0072527	pyrimidine-containing compound metabolic process	ARBA:ARBA00026859	MODULE_INCOMPLETE	False	pyrimidine_nucleotide_catabolism|pyrimidine_salvage	pyrimidine_nucleotide_catabolism:uridine_phosphorolysis|pyrimidine_nucleotide_catabolism:thymidine_phosphorolysis|pyrimidine_nucleotide_catabolism:dihydropyrimidine_reduction|pyrimidine_nucleotide_catabolism:dihydropyrimidine_hydrolysis|pyrimidine_nucleotide_catabolism:ureidopropionase|pyrimidine_salvage:cmp_kinase_step	pyrimidine_nucleotide_catabolism:cda_activity|pyrimidine_salvage:cytidine_deaminase_activity	heat_shock_response|phenylacetate_catabolism	MODIFY
yeast/CDD1	Q06549	559292	GO:1901135	carbohydrate derivative metabolic process	ARBA:ARBA00026297	NOT_ENTAILED	False	adp_heptose_biosynthesis|bacterial_methionine_cycle|d_amino_acid_cell_wall_precursor_supply|de_novo_purine_synthesis|de_novo_pyrimidine_synthesis			heat_shock_response|phenylacetate_catabolism|pyrimidine_nucleotide_catabolism|pyrimidine_salvage	MODIFY
yeast/CHD1	P32657	559292	GO:0006366	transcription by RNA polymerase II	ARBA:ARBA00028158	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenylacetate_catabolism|phosphoty	ACCEPT
yeast/CHD1	P32657	559292	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenylacetate_catabolism|phosphoty	ACCEPT
yeast/CHD1	P32657	559292	GO:0034728	nucleosome organization	ARBA:ARBA00085234	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenylacetate_catabolism|phosphoty	ACCEPT
yeast/CHO1	P08456	559292	GO:0006659	phosphatidylserine biosynthetic process	ARBA:ARBA00087337	ENTAILED	True	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:cho1_activity	sphingolipid_de_novo_synthesis	ACCEPT
yeast/CLN2	P20438	559292	GO:0007089	traversing start control point of mitotic cell cycle	ARBA:ARBA00092120	NO_MODULE	False				g1_s_transition|scer_hog1_cascade|sphingolipid_de_novo_synthesis	ACCEPT
yeast/CLN3	P13365	559292	GO:0044772	mitotic cell cycle phase transition	ARBA:ARBA00027525	ENTAILED	False	g1_s_transition		g1_s_transition:g1_cyclin|g1_s_transition:g1s_cyclin	scer_hog1_cascade|sphingolipid_de_novo_synthesis	MODIFY
yeast/COQ1	P18900	559292	GO:1901663	quinone biosynthetic process	ARBA:ARBA00026910	NOT_ENTAILED	False	coenzyme_q10_biosynthesis|ubiquinone_biosynthesis			methionine_biosynthesis	MODIFY
yeast/COQ5	P49017	559292	GO:0042181	ketone biosynthetic process	ARBA:ARBA00027493	ENTAILED	False	ubiquinone_biosynthesis		ubiquinone_biosynthesis:c_methyltransferase_activity|ubiquinone_biosynthesis:coq5_c_methyltransferase_activity	methionine_cycle	MODIFY
yeast/CPR6	P53691	559292	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				complex_i_assembly_factors|methylcitrate_cycle|phenylacetate_catabolism|retinoid_visual_cycle	ACCEPT
yeast/CPR7	P47103	559292	GO:0042026	protein refolding	ARBA:ARBA00043587	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|retinoid_visual_cycle	ACCEPT
yeast/CRD1	Q07560	559292	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:crd1_activity	sphingolipid_de_novo_synthesis	ACCEPT
yeast/CRD1	Q07560	559292	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	cdp_dag_phospholipid_synthesis|sphingolipid_de_novo_synthesis		cdp_dag_phospholipid_synthesis:crd1_activity|sphingolipid_de_novo_synthesis:ipt1_activity		MODIFY
yeast/CRH1	P53301	559292	GO:0031505	fungal-type cell wall organization	ARBA:ARBA00026542	NO_MODULE	False				phenylacetate_catabolism	ACCEPT
yeast/CSH1	P38287	559292	GO:0006676	mannosyl diphosphorylinositol ceramide metabolic process	ARBA:ARBA00087413	NO_MODULE	False				sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/CSH1	P38287	559292	GO:0006688	glycosphingolipid biosynthetic process	ARBA:ARBA00043439	NOT_ENTAILED	True	glycosphingolipid_biosynthesis			sphingolipid_de_novo_synthesis	ACCEPT
yeast/CTA1	P15202	559292	GO:0000302	response to reactive oxygen species	ARBA:ARBA00027603	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|mitochondrial_complex_ii	KEEP_AS_NON_CORE
yeast/CTA1	P15202	559292	GO:0042744	hydrogen peroxide catabolic process	ARBA:ARBA00088409	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|mitochondrial_complex_ii	ACCEPT
yeast/CYB5	P40312	559292	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	ergosterol_biosynthesis		ergosterol_biosynthesis:cyb5_activity	electron_transfer_flavoprotein_system|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|ubiquinone_biosynthesis	ACCEPT
yeast/CYC1	P00044	559292	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	ARBA:ARBA00084238	ENTAILED	True	mitochondrial_complex_iii		mitochondrial_complex_iii:cyc1_activity|mitochondrial_complex_iii:uqcc3_activity|mitochondrial_complex_iii:uqcrfs1_activity	electron_transfer_flavoprotein_system|ergosterol_biosynthesis|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|ubiquinone_biosynthesis	ACCEPT
yeast/CYC1	P00044	559292	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	ARBA:ARBA00084245	NOT_ENTAILED	True	mitochondrial_complex_iv			electron_transfer_flavoprotein_system|ergosterol_biosynthesis|hydroxycinnamate_vanillate_catabolism|mitochondrial_complex_i_core|mitochondrial_complex_ii|mitochondrial_complex_iii|ubiquinone_biosynthesis	ACCEPT
yeast/CYS4	P32582	559292	GO:0000096	sulfur amino acid metabolic process	ARBA:ARBA00028668	ENTAILED	False	fungal_sulfur_amino_acid_transsulfuration|methionine_cycle		fungal_sulfur_amino_acid_transsulfuration:cystathionine_beta_synthase_activity|methionine_cycle:cbs_activity	methylcitrate_cycle	ACCEPT
yeast/CYS4	P32582	559292	GO:0044272	sulfur compound biosynthetic process	ARBA:ARBA00028512	NOT_ENTAILED	False	bacterial_cysteine_biosynthesis_via_o_acetylserine|biotin_biosynthesis|coenzyme_a_biosynthesis|eukaryotic_thiamine_biosynthesis|fatty_acid_de_novo_synthesis			fungal_sulfur_amino_acid_transsulfuration|homocysteine_metabolism|methionine_cycle|methylcitrate_cycle	ACCEPT
yeast/DBP5	P20449	559292	GO:0010467	gene expression	ARBA:ARBA00028330	NOT_ENTAILED	False	cct_chaperonin_folding|endogenous_protein_lipoylation|gpi_anchor_core_glycan_assembly|gpi_anchor_ethanolamine_phosphate|gpi_anchor_glcnac_transferase			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|methylcitrate_cycle|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
yeast/DNM1	P54861	559292	GO:0000266	mitochondrial fission	ARBA:ARBA00090200	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	ACCEPT
yeast/DNM1	P54861	559292	GO:0016559	peroxisome fission	ARBA:ARBA00027945	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	ACCEPT
yeast/DNM1	P54861	559292	GO:0030001	metal ion transport	ARBA:ARBA00028072	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	REMOVE
yeast/DNM1	P54861	559292	GO:0048311	mitochondrion distribution	ARBA:ARBA00089905	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|heat_shock_response|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	KEEP_AS_NON_CORE
yeast/DOT5	P40553	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
yeast/ECM31	P38122	559292	GO:0072330	monocarboxylic acid biosynthetic process	ARBA:ARBA00027175	ENTAILED	False	coenzyme_a_biosynthesis		coenzyme_a_biosynthesis:panB_activity		MODIFY
yeast/EGD1	Q02642	559292	GO:0006613	cotranslational protein targeting to membrane	ARBA:ARBA00087310	NO_MODULE	False					KEEP_AS_NON_CORE
yeast/ERG1	P32476	559292	GO:0008204	ergosterol metabolic process	ARBA:ARBA00092291	ENTAILED	False	ergosterol_biosynthesis		ergosterol_biosynthesis:erg1_activity	complex_i_assembly_factors|sterol_commitment_squalene_to_lanosterol	MODIFY
yeast/ERG11	P10614	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg11_activity	cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors|mitochondrial_complex_ii	ACCEPT
yeast/ERG24	P32462	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg24_activity	cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors	ACCEPT
yeast/ERG26	P53199	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg26_activity	cholesterol_synthesis_post_lanosterol|complex_i_assembly_factors	ACCEPT
yeast/ERG6	P25087	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg6_activity	bacterial_methionine_cycle|heat_shock_response|methionine_cycle	ACCEPT
yeast/ERG7	P38604	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg7_activity	methylcitrate_cycle|phenylacetate_catabolism|sterol_commitment_squalene_to_lanosterol	ACCEPT
yeast/ERG9	P29704	559292	GO:0006696	ergosterol biosynthetic process	ARBA:ARBA00087364	ENTAILED	True	ergosterol_biosynthesis		ergosterol_biosynthesis:erg9_activity	methionine_biosynthesis|sterol_commitment_squalene_to_lanosterol	ACCEPT
yeast/ESA1	Q08649	559292	GO:0006357	regulation of transcription by RNA polymerase II	ARBA:ARBA00028137	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/ESA1	Q08649	559292	GO:0006974	DNA damage response	ARBA:ARBA00026271	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|muth_independent_mismatch_repair			alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/ESA1	Q08649	559292	GO:0010629	negative regulation of gene expression	ARBA:ARBA00026647	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
yeast/ESP1	Q03018	559292	GO:0000280	nuclear division	ARBA:ARBA00028466	MODULE_INCOMPLETE	False	metaphase_anaphase_transition_and_mitotic_exit	metaphase_anaphase_transition_and_mitotic_exit:securin_separase_cohesin	metaphase_anaphase_transition_and_mitotic_exit:separase	phenylacetate_catabolism|protease_activation_cascade	MODIFY
yeast/ESP1	Q03018	559292	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				metaphase_anaphase_transition_and_mitotic_exit|phenylacetate_catabolism|protease_activation_cascade	ACCEPT
yeast/EUG1	P32474	559292	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|methylcitrate_cycle|oligosaccharyltransferase_complex|phenylacetate_catabolism	ACCEPT
yeast/FAS1	P07149	559292	GO:0042759	long-chain fatty acid biosynthetic process	ARBA:ARBA00034980	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_unsaturated_fatty_acid_biosynthesis|complex_i_assembly_factors|fatty_acid_de_novo_synthesis|gpi_anchor_remodeling|methylcitrate_cycle|phenylacetate_catabolism|type_ii_fatty_acid_synthesis	ACCEPT
yeast/FCY1	Q12178	559292	GO:0019858	cytosine metabolic process	ARBA:ARBA00085453	NO_MODULE	False				phenylacetate_catabolism|pyrimidine_salvage|riboflavin_biosynthesis	ACCEPT
yeast/FOL2	P51601	559292	GO:0009396	folic acid-containing compound biosynthetic process	ARBA:ARBA00029164	MODULE_INCOMPLETE	False	tetrahydrofolate_biosynthesis	tetrahydrofolate_biosynthesis:dihydroneopterin_dephosphorylation_step	tetrahydrofolate_biosynthesis:gtp_cyclohydrolase_i_activity	phenylacetate_catabolism|tetrahydrobiopterin_metabolism	ACCEPT
yeast/FUN19	P28003	559292	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation				ACCEPT
yeast/FUR1	P18562	559292	GO:0008655	pyrimidine-containing compound salvage	ARBA:ARBA00084547	MODULE_INCOMPLETE	True	pyrimidine_salvage	pyrimidine_salvage:cmp_kinase_step	pyrimidine_salvage:uracil_prt_activity		ACCEPT
yeast/FUS3	P16892	559292	GO:0000749	response to pheromone triggering conjugation with cellular fusion	ARBA:ARBA00090899	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_casca	ACCEPT
yeast/FUS3	P16892	559292	GO:0001403	invasive growth in response to glucose limitation	ARBA:ARBA00090378	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_casca	MODIFY
yeast/GCG1	P32656	559292	GO:0006749	glutathione metabolic process	ARBA:ARBA00027824	ENTAILED	False	glutathione_synthesis_gamma_glutamyl_cycle		glutathione_synthesis_gamma_glutamyl_cycle:chac1_activity|glutathione_synthesis_gamma_glutamyl_cycle:ggct_activity		ACCEPT
yeast/GCN5	Q03330	559292	GO:0006338	chromatin remodeling	ARBA:ARBA00027994	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	ACCEPT
yeast/GCN5	Q03330	559292	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			alginate_o_acetylation|bacterial_l_carnitine_catabolism|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	MARK_AS_OVER_ANNOTATED
yeast/GCN5	Q03330	559292	GO:0010557	positive regulation of macromolecule biosynthetic process	ARBA:ARBA00027412	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|ergosterol_biosynthesis|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|vesicle_coat_budding	MARK_AS_OVER_ANNOTATED
yeast/GDH1	P07262	559292	GO:0097054	L-glutamate biosynthetic process	ARBA:ARBA00090393	ENTAILED	True	nitrogen_assimilation_glutamate_glutamine		nitrogen_assimilation_glutamate_glutamine:nadp_glutamate_dehydrogenase_activity	complex_i_assembly_factors|glutamate_glutamine_ammonia_hub	ACCEPT
yeast/GDH3	P39708	559292	GO:0097054	L-glutamate biosynthetic process	ARBA:ARBA00090393	ENTAILED	True	nitrogen_assimilation_glutamate_glutamine		nitrogen_assimilation_glutamate_glutamine:nadp_glutamate_dehydrogenase_activity	complex_i_assembly_factors|glutamate_glutamine_ammonia_hub	ACCEPT
yeast/GLO2	Q05584	559292	GO:0051596	methylglyoxal catabolic process	ARBA:ARBA00043291	ENTAILED	True	methylglyoxal_detoxification		methylglyoxal_detoxification:glo2_cytosolic_activity|methylglyoxal_detoxification:glo4_mitochondrial_activity|methylglyoxal_detoxification:gloB_activity	gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
yeast/GLO4	Q12320	559292	GO:0051596	methylglyoxal catabolic process	ARBA:ARBA00043291	ENTAILED	True	methylglyoxal_detoxification		methylglyoxal_detoxification:glo2_cytosolic_activity|methylglyoxal_detoxification:glo4_mitochondrial_activity|methylglyoxal_detoxification:gloB_activity	gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
yeast/GLT1	Q12680	559292	GO:0019676	ammonia assimilation cycle	ARBA:ARBA00086168	NO_MODULE	False				complex_i_assembly_factors|nitrogen_assimilation_glutamate_glutamine	ACCEPT
yeast/GPT2	P36148	559292	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:fungal_dhapat_activity|triacylglycerol_biosynthesis:fungal_gpat_activity|triacylglycerol_biosynthesis:gpam_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/GRX1	P25373	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|methionine_biosynthesis|oligosaccharyltransferase_complex	ACCEPT
yeast/GRX2	P17695	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|methionine_biosynthesis|oligosaccharyltransferase_complex	ACCEPT
yeast/GUA1	P38625	559292	GO:0046037	GMP metabolic process	ARBA:ARBA00027112	ENTAILED	False	purine_nucleotide_interconversion		purine_nucleotide_interconversion:gmps_activity		KEEP_AS_NON_CORE
yeast/GUD1	Q07729	559292	GO:0046098	guanine metabolic process	ARBA:ARBA00090781	NO_MODULE	False				phenylacetate_catabolism|purine_nucleotide_catabolism|purine_salvage_and_catabolism	MODIFY
yeast/GUK1	P15454	559292	GO:0046037	GMP metabolic process	ARBA:ARBA00027112	ENTAILED	False	purine_nucleotide_interconversion		purine_nucleotide_interconversion:guanylate_kinase_activity	coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/HDA1	P53973	559292	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				gpi_anchor_remodeling|heat_shock_response|phenylacetate_catabolism	ACCEPT
yeast/HDA1	P53973	559292	GO:0010557	positive regulation of macromolecule biosynthetic process	ARBA:ARBA00027412	NO_MODULE	False				gpi_anchor_remodeling|heat_shock_response|phenylacetate_catabolism	REMOVE
yeast/HEM1	P09950	559292	GO:0006783	heme biosynthetic process	ARBA:ARBA00027909	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:c4_alas_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/HEM12	P32347	559292	GO:0006778	porphyrin-containing compound metabolic process	ARBA:ARBA00027898	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:urod_activity	type_ii_fatty_acid_synthesis	MODIFY
yeast/HEM13	P11353	559292	GO:0006783	heme biosynthetic process	ARBA:ARBA00027909	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:hemf_activity	complex_i_assembly_factors|heat_shock_response	ACCEPT
yeast/HEM3	P28789	559292	GO:0006783	heme biosynthetic process	ARBA:ARBA00027909	ENTAILED	False	heme_biosynthesis		heme_biosynthesis:hemc_activity	methionine_biosynthesis	ACCEPT
yeast/HFA1	P32874	559292	GO:0042759	long-chain fatty acid biosynthetic process	ARBA:ARBA00034980	NO_MODULE	False				bacterial_pyruvate_metabolism|fatty_acid_de_novo_synthesis|leucine_catabolism|type_ii_fatty_acid_synthesis	MARK_AS_OVER_ANNOTATED
yeast/HOM3	P10869	559292	GO:0009090	L-homoserine biosynthetic process	ARBA:ARBA00091436	NO_MODULE	False				aspartate_family_threonine_biosynthesis|coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	ACCEPT
yeast/HOM3	P10869	559292	GO:0071266	'de novo' L-methionine biosynthetic process	ARBA:ARBA00092877	NOT_ENTAILED	True	methionine_biosynthesis			aspartate_family_threonine_biosynthesis|coenzyme_a_biosynthesis|sphingolipid_de_novo_synthesis	ACCEPT
yeast/HPT1	Q04178	559292	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	ARBA:ARBA00027608	NOT_ENTAILED	False	de_novo_purine_synthesis|purine_nucleotide_interconversion			purine_salvage_and_catabolism	ACCEPT
yeast/HPT1	Q04178	559292	GO:0106380	purine ribonucleotide salvage	ARBA:ARBA00090487	NO_MODULE	False				purine_salvage_and_catabolism	ACCEPT
yeast/HRT1	Q08273	559292	GO:0010498	proteasomal protein catabolic process	ARBA:ARBA00028386	NO_MODULE	False				alginate_o_acetylation|cell_cycle_progression|ergosterol_biosynthesis|g1_s_transition|metaphase_anaphase_transition_and_mitotic_exit|oligosaccharyltransferase_complex|peroxisome-lifecycle|phosphotyrosine_adaptor_recruitment|pyruvate_metabolism|ubiquitin_transfer_relay|vesicle_coat_budding	ACCEPT
yeast/HSC82	P15108	559292	GO:0000492	box C/D snoRNP assembly	ARBA:ARBA00089701	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/HSC82	P15108	559292	GO:0043248	proteasome assembly	ARBA:ARBA00028936	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/HSP104	P31539	559292	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/HSP104	P31539	559292	GO:0034605	cellular response to heat	ARBA:ARBA00026567	ENTAILED	True	heat_shock_response		heat_shock_response:hsp12_6_shsp	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/HSP104	P31539	559292	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/HSP26	P15992	559292	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			heat_shock_response	MARK_AS_OVER_ANNOTATED
yeast/HSP78	P33416	559292	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/HSP78	P33416	559292	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/HSP78	P33416	559292	GO:0043335	protein unfolding	ARBA:ARBA00086271	NO_MODULE	False				bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/HSP82	P02829	559292	GO:0000492	box C/D snoRNP assembly	ARBA:ARBA00089701	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/HSP82	P02829	559292	GO:0043248	proteasome assembly	ARBA:ARBA00028936	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/HST1	P53685	559292	GO:0030466	silent mating-type cassette heterochromatin formation	ARBA:ARBA00087185	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|g1_s_transition|gpi_anchor_remodeling	KEEP_AS_NON_CORE
yeast/HST1	P53685	559292	GO:0045910	negative regulation of DNA recombination	ARBA:ARBA00086129	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|g1_s_transition|gpi_anchor_remodeling	UNDECIDED
yeast/HST2	P53686	559292	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling	KEEP_AS_NON_CORE
yeast/HST3	P53687	559292	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|gpi_anchor_remodeling	KEEP_AS_NON_CORE
yeast/IDI1	P15496	559292	GO:0050993	dimethylallyl diphosphate metabolic process	ARBA:ARBA00098399	ENTAILED	False	isoprenoid_diphosphate_biosynthesis		isoprenoid_diphosphate_biosynthesis:idi_activity	methylcitrate_cycle|phenylacetate_catabolism	MODIFY
yeast/IFA38	P38286	559292	GO:0030148	sphingolipid biosynthetic process	ARBA:ARBA00027455	NOT_ENTAILED	True	glycosphingolipid_biosynthesis|sphingolipid_de_novo_synthesis|sphingomyelin_cycle			complex_i_assembly_factors|fatty_acid_elongation_cycle	KEEP_AS_NON_CORE
yeast/INM1	P38710	559292	GO:0071545	inositol phosphate catabolic process	ARBA:ARBA00092427	NO_MODULE	False				gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/INM2	Q05533	559292	GO:0071545	inositol phosphate catabolic process	ARBA:ARBA00092427	NO_MODULE	False				gpi_anchor_remodeling|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/IRE1	P32361	559292	GO:0031505	fungal-type cell wall organization	ARBA:ARBA00026542	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/KAR2	P16474	559292	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ARBA:ARBA00087312	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/KAR2	P16474	559292	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/KAR2	P16474	559292	GO:0033554	cellular response to stress	ARBA:ARBA00028184	ENTAILED	False	heat_shock_response		heat_shock_response:hsp12_3_shsp|heat_shock_response:shsp_holdase_activity	cct_chaperonin_folding|coenzyme_q10_biosynthesis|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/KDX1	P36005	559292	GO:0007165	signal transduction	ARBA:ARBA00029050	ENTAILED	False	gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling		gpcr_camp_pka_signaling:pka_catalytic_subunit|gpcr_plc_calcium_pkc_signaling:protein_kinase_c	cell_cycle_progression|coenzyme_a_biosynthesis|g1_s_transition|g2_m_transition|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/KDX1	P36005	559292	GO:0009272	fungal-type cell wall biogenesis	ARBA:ARBA00033809	NO_MODULE	False				cell_cycle_progression|coenzyme_a_biosynthesis|g1_s_transition|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/KSS1	P14681	559292	GO:0000749	response to pheromone triggering conjugation with cellular fusion	ARBA:ARBA00090899	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_cascade|scer_mating_fus3_	ACCEPT
yeast/KSS1	P14681	559292	GO:0001403	invasive growth in response to glucose limitation	ARBA:ARBA00090378	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_cascade|scer_mating_fus3_	ACCEPT
yeast/LRO1	P40345	559292	GO:0019432	triglyceride biosynthetic process	ARBA:ARBA00026657	ENTAILED	True	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:pdat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/LRO1	P40345	559292	GO:0019915	lipid storage	ARBA:ARBA00028621	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|triacylglycerol_biosynthesis	KEEP_AS_NON_CORE
yeast/LYS9	P38999	559292	GO:0009085	L-lysine biosynthetic process	ARBA:ARBA00028431	ENTAILED	True	lysine_biosynthesis_aminoadipate		lysine_biosynthesis_aminoadipate:saccharopine_reductase_activity	complex_i_assembly_factors|hydroxyproline_catabolism	ACCEPT
yeast/MAD2	P40958	559292	GO:0007094	mitotic spindle assembly checkpoint signaling	ARBA:ARBA00044419	NO_MODULE	False					ACCEPT
yeast/MDM12	Q92328	559292	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis			chylomicron_assembly_secretion|cobalamin_intracellular_processing	ACCEPT
yeast/MDM34	P53083	559292	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis				ACCEPT
yeast/MET16	P18408	559292	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction		aps_dependent_assimilatory_sulfate_reduction:paps_reductase_activity	complex_i_assembly_factors	ACCEPT
yeast/MET2	P08465	559292	GO:0006555	L-methionine metabolic process	ARBA:ARBA00026499	ENTAILED	False	methionine_biosynthesis		methionine_biosynthesis:homoserine_o_acetyltransferase_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
yeast/MET3	P08536	559292	GO:0006790	sulfur compound metabolic process	ARBA:ARBA00028021	ENTAILED	False	aps_dependent_assimilatory_sulfate_reduction|paps_sulfate_activation		aps_dependent_assimilatory_sulfate_reduction:cysdn_atp_sulfurylase|aps_dependent_assimilatory_sulfate_reduction:met3_type_atp_sulfurylase|paps_sulfate_activation:papss_atp_sulfurylase	sphingolipid_de_novo_synthesis	ACCEPT
yeast/MET5	P47169	559292	GO:0000103	sulfate assimilation	ARBA:ARBA00033980	ENTAILED	True	aps_dependent_assimilatory_sulfate_reduction		aps_dependent_assimilatory_sulfate_reduction:cysji_nadph_sulfite_reductase|aps_dependent_assimilatory_sulfate_reduction:met10_met5_nadph_sulfite_reductase	complex_i_assembly_factors|mitochondrial_complex_ii	ACCEPT
yeast/MET6	P05694	559292	GO:0071265	L-methionine biosynthetic process	ARBA:ARBA00092883	ENTAILED	False	methionine_biosynthesis		methionine_biosynthesis:metE_activity|methionine_biosynthesis:metH_activity	bacterial_methionine_cycle|homocysteine_metabolism|methionine_cycle	ACCEPT
yeast/MMM1	P41800	559292	GO:0006869	lipid transport	ARBA:ARBA00027046	NOT_ENTAILED	False	carnitine_shuttle|ldl_receptor_mediated_endocytosis			chylomicron_assembly_secretion|cobalamin_intracellular_processing	ACCEPT
yeast/MPS1	P54199	559292	GO:0098813	nuclear chromosome segregation	ARBA:ARBA00027947	NO_MODULE	False				coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_cascade|scer_mating_fus3_	ACCEPT
yeast/MSS4	P38994	559292	GO:0046854	phosphatidylinositol phosphate biosynthetic process	ARBA:ARBA00028323	ENTAILED	True	phosphoinositide_biosynthesis		phosphoinositide_biosynthesis:mss4_activity	coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/NDI1	P32340	559292	GO:0015980	energy derivation by oxidation of organic compounds	ARBA:ARBA00026991	MODULE_INCOMPLETE	False	mitochondrial_complex_i_core	mitochondrial_complex_i_core:complex_i_q_module	mitochondrial_complex_i_core:ndufv1_activity	complex_i_assembly_factors|heat_shock_response	ACCEPT
yeast/NTE1	Q04958	559292	GO:0046486	glycerolipid metabolic process	ARBA:ARBA00028375	ENTAILED	False	gpi_anchor_remodeling		gpi_anchor_remodeling:pgap3_activity	phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
yeast/ODC1	Q03028	559292	GO:0006839	mitochondrial transport	ARBA:ARBA00027061	ENTAILED	False	mitochondrial_nucleotide_glycine_carriers		mitochondrial_nucleotide_glycine_carriers:slc25a24_activity	lysine_biosynthesis_aminoadipate|mitochondrial_dicarboxylate_tricarboxylate_carriers|oxphos_adenine_nucleotide_phosphate_carriers|urea_cycle	MODIFY
yeast/ODC2	Q99297	559292	GO:0006839	mitochondrial transport	ARBA:ARBA00027061	ENTAILED	False	mitochondrial_nucleotide_glycine_carriers		mitochondrial_nucleotide_glycine_carriers:slc25a24_activity	lysine_biosynthesis_aminoadipate|mitochondrial_dicarboxylate_tricarboxylate_carriers|oxphos_adenine_nucleotide_phosphate_carriers|urea_cycle	MODIFY
yeast/PAP2	P53632	559292	GO:0034475	U4 snRNA 3'-end processing	ARBA:ARBA00092747	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	ARBA:ARBA00090756	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071036	nuclear polyadenylation-dependent snoRNA catabolic process	ARBA:ARBA00090754	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071037	nuclear polyadenylation-dependent snRNA catabolic process	ARBA:ARBA00090753	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071038	TRAMP-dependent tRNA surveillance pathway	ARBA:ARBA00027023	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071039	nuclear polyadenylation-dependent CUT catabolic process	ARBA:ARBA00090757	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process	ARBA:ARBA00090807	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071044	histone mRNA catabolic process	ARBA:ARBA00090803	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PAP2	P53632	559292	GO:0071051	poly(A)-dependent snoRNA 3'-end processing	ARBA:ARBA00090788	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/PBS2	P08018	559292	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map2k_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|coenzyme_a_biosynthesis|complex_i_accessory_subunits|ergosterol_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial	ACCEPT
yeast/PBS2	P08018	559292	GO:0071470	cellular response to osmotic stress	ARBA:ARBA00027118	ENTAILED	False	scer_hog1_cascade		scer_hog1_cascade:hog1_map2k_activity|scer_hog1_cascade:sho1_scaffold_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism|coenzyme_a_biosynthesis|complex_i_accessory_subunits|ergosterol_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_complex_i_core|mitochondrial	ACCEPT
yeast/PDC1	P06169	559292	GO:0006067	ethanol metabolic process	ARBA:ARBA00043340	NO_MODULE	False				ehrlich_pathway|type_ii_fatty_acid_synthesis	MODIFY
yeast/PDC1	P06169	559292	GO:0006559	L-phenylalanine catabolic process	ARBA:ARBA00085541	NOT_ENTAILED	True	tyrosine_catabolism			ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDC1	P06169	559292	GO:0006569	L-tryptophan catabolic process	ARBA:ARBA00026552	NOT_ENTAILED	True	kynurenine_nad_de_novo			ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDC5	P16467	559292	GO:0006067	ethanol metabolic process	ARBA:ARBA00043340	NO_MODULE	False				ehrlich_pathway|type_ii_fatty_acid_synthesis	MODIFY
yeast/PDC5	P16467	559292	GO:0006559	L-phenylalanine catabolic process	ARBA:ARBA00085541	NOT_ENTAILED	True	tyrosine_catabolism			ehrlich_pathway|type_ii_fatty_acid_synthesis	ACCEPT
yeast/PDC5	P16467	559292	GO:0006569	L-tryptophan catabolic process	ARBA:ARBA00026552	NOT_ENTAILED	True	kynurenine_nad_de_novo			ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDC6	P26263	559292	GO:0006067	ethanol metabolic process	ARBA:ARBA00043340	NO_MODULE	False				ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDC6	P26263	559292	GO:0006559	L-phenylalanine catabolic process	ARBA:ARBA00085541	NOT_ENTAILED	True	tyrosine_catabolism			ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDC6	P26263	559292	GO:0006569	L-tryptophan catabolic process	ARBA:ARBA00026552	NOT_ENTAILED	True	kynurenine_nad_de_novo			ehrlich_pathway|type_ii_fatty_acid_synthesis	KEEP_AS_NON_CORE
yeast/PDI1	P17967	559292	GO:0006457	protein folding	ARBA:ARBA00027200	NOT_ENTAILED	True	cct_chaperonin_folding			aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|methylcitrate_cycle|oligosaccharyltransferase_complex|phenylacetate_catabolism	ACCEPT
yeast/PDX3	P38075	559292	GO:0042816	vitamin B6 metabolic process	ARBA:ARBA00027956	ENTAILED	True	vitamin_b6_plp_metabolism		vitamin_b6_plp_metabolism:pnpo_activity	complex_i_assembly_factors|gamma_glutamyl_putrescine_catabolism	MODIFY
yeast/PHA2	P32452	559292	GO:0006520	amino acid metabolic process	ARBA:ARBA00026411	ENTAILED	False	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:prephenate_dehydratase	methylcitrate_cycle	MODIFY
yeast/PHA2	P32452	559292	GO:0046394	carboxylic acid biosynthetic process	ARBA:ARBA00027883	ENTAILED	False	phenylalanine_tyrosine_biosynthesis		phenylalanine_tyrosine_biosynthesis:prephenate_dehydratase	methylcitrate_cycle	MODIFY
yeast/PIK1	P39104	559292	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			coenzyme_a_biosynthesis|peptidoglycan_recycling|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
yeast/PIS1	P06197	559292	GO:0006661	phosphatidylinositol biosynthetic process	ARBA:ARBA00028655	ENTAILED	True	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:pis1_activity	sphingolipid_de_novo_synthesis	ACCEPT
yeast/POF1	P25576	559292	GO:0009165	nucleotide biosynthetic process	ARBA:ARBA00027613	ENTAILED	False	nad_biosynthesis_salvage|nad_de_novo_and_salvage_fungal		nad_biosynthesis_salvage:nmnat_nmn_activity|nad_de_novo_and_salvage_fungal:nma_nmn_adenylyltransferase_activity|nad_de_novo_and_salvage_fungal:pof1_nmn_adenylyltransferase_activity	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|linc_complex|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	MODIFY
yeast/PPH21	P23594	559292	GO:0000082	G1/S transition of mitotic cell cycle	ARBA:ARBA00028571	NOT_ENTAILED	True	g1_s_transition			g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
yeast/PPH21	P23594	559292	GO:0006417	regulation of translation	ARBA:ARBA00027123	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	MARK_AS_OVER_ANNOTATED
yeast/PPH21	P23594	559292	GO:1903432	regulation of TORC1 signaling	ARBA:ARBA00027049	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	MODIFY
yeast/PPH21	P23594	559292	GO:2000786	positive regulation of autophagosome assembly	ARBA:ARBA00085986	NO_MODULE	False				g2_m_transition|gpi_anchor_remodeling|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|phenylacetate_catabolism	ACCEPT
yeast/PSD1	P39006	559292	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:psd1_activity|cdp_dag_phospholipid_synthesis:psd2_activity	type_ii_fatty_acid_synthesis	ACCEPT
yeast/PSD2	P53037	559292	GO:0046474	glycerophospholipid biosynthetic process	ARBA:ARBA00028351	ENTAILED	False	cdp_dag_phospholipid_synthesis		cdp_dag_phospholipid_synthesis:psd1_activity|cdp_dag_phospholipid_synthesis:psd2_activity	type_ii_fatty_acid_synthesis	ACCEPT
yeast/RAD27	P26793	559292	GO:0006281	DNA repair	ARBA:ARBA00029008	MODULE_INCOMPLETE	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection	bacterial_nucleotide_excision_repair:liga_sealing|bacterial_recbcd_end_resection:recb_resection	bacterial_nucleotide_excision_repair:uvrc_activity|bacterial_recbcd_end_resection:recc_scaffold_activity	gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
yeast/RAS2	P01120	559292	GO:0097271	protein localization to bud neck	ARBA:ARBA00089788	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	REMOVE
yeast/RIB2	Q12362	559292	GO:0031119	tRNA pseudouridine synthesis	ARBA:ARBA00026724	NO_MODULE	False				methylcitrate_cycle|phenylacetate_catabolism|riboflavin_biosynthesis	ACCEPT
yeast/RIM15	P43565	559292	GO:0006950	response to stress	ARBA:ARBA00026300	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/RIM15	P43565	559292	GO:1901992	positive regulation of mitotic cell cycle phase transition	ARBA:ARBA00029089	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/RPD3	P32561	559292	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				g1_s_transition|gpi_anchor_remodeling|phenylacetate_catabolism	ACCEPT
yeast/RPD3	P32561	559292	GO:0051052	regulation of DNA metabolic process	ARBA:ARBA00027282	NO_MODULE	False				g1_s_transition|gpi_anchor_remodeling|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SAM1	P10659	559292	GO:0006555	L-methionine metabolic process	ARBA:ARBA00026499	ENTAILED	False	bacterial_methionine_cycle|methionine_biosynthesis|methionine_cycle		bacterial_methionine_cycle:metk_activity|methionine_biosynthesis:metZ_activity|methionine_cycle:mat1_activity|methionine_cycle:mat3_activity|methionine_cycle:mat_single_chain_activity		ACCEPT
yeast/SAM2	P19358	559292	GO:0006555	L-methionine metabolic process	ARBA:ARBA00026499	ENTAILED	False	bacterial_methionine_cycle|methionine_biosynthesis|methionine_cycle		bacterial_methionine_cycle:metk_activity|methionine_biosynthesis:metZ_activity|methionine_cycle:mat1_activity|methionine_cycle:mat3_activity|methionine_cycle:mat_single_chain_activity		KEEP_AS_NON_CORE
yeast/SAS2	P40963	559292	GO:0010468	regulation of gene expression	ARBA:ARBA00028334	NOT_ENTAILED	False	selenocysteine_biosynthesis_incorporation			alginate_o_acetylation|bacterial_l_carnitine_catabolism	MARK_AS_OVER_ANNOTATED
yeast/SAS3	P34218	559292	GO:0031507	heterochromatin formation	ARBA:ARBA00033536	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism	KEEP_AS_NON_CORE
yeast/SCS7	Q03529	559292	GO:0008610	lipid biosynthetic process	ARBA:ARBA00027236	ENTAILED	False	sphingolipid_de_novo_synthesis		sphingolipid_de_novo_synthesis:scs7_activity|sphingolipid_de_novo_synthesis:sur2_c4_hydroxylase_activity	complex_i_assembly_factors|mitochondrial_complex_ii	ACCEPT
yeast/SCT1	P32784	559292	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:fungal_dhapat_activity|triacylglycerol_biosynthesis:fungal_gpat_activity|triacylglycerol_biosynthesis:gpam_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/SER33	P40510	559292	GO:0006564	L-serine biosynthetic process	ARBA:ARBA00093701	ENTAILED	True	phosphorylated_serine_biosynthesis|serine_biosynthesis_one_carbon		phosphorylated_serine_biosynthesis:serA_activity|serine_biosynthesis_one_carbon:phgdh_activity	complex_i_assembly_factors|heat_shock_response	ACCEPT
yeast/SET1	P38827	559292	GO:0006325	chromatin organization	ARBA:ARBA00028060	NO_MODULE	False				bacterial_methionine_cycle|methionine_cycle	ACCEPT
yeast/SET1	P38827	559292	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_methionine_cycle|methionine_cycle	ACCEPT
yeast/SIR2	P06700	559292	GO:0030466	silent mating-type cassette heterochromatin formation	ARBA:ARBA00087185	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|gpi_anchor_remodeling	ACCEPT
yeast/SIR2	P06700	559292	GO:0045910	negative regulation of DNA recombination	ARBA:ARBA00086129	NO_MODULE	False				alginate_o_acetylation|bacterial_l_carnitine_catabolism|bacterial_recbcd_end_resection|complex_i_assembly_factors|g1_s_transition|gpi_anchor_remodeling	ACCEPT
yeast/SIZ1	Q04195	559292	GO:0007059	chromosome segregation	ARBA:ARBA00026830	NO_MODULE	False				alginate_o_acetylation|bacterial_recbcd_end_resection	KEEP_AS_NON_CORE
yeast/SIZ1	Q04195	559292	GO:1990683	DNA double-strand break attachment to nuclear envelope	ARBA:ARBA00088737	NO_MODULE	False				alginate_o_acetylation|bacterial_recbcd_end_resection	KEEP_AS_NON_CORE
yeast/SLC1	P33333	559292	GO:0006644	phospholipid metabolic process	ARBA:ARBA00028721	ENTAILED	False	triacylglycerol_biosynthesis		triacylglycerol_biosynthesis:agpat2_activity|triacylglycerol_biosynthesis:loa1_lpaat_activity|triacylglycerol_biosynthesis:mboat_lpaat_activity	alginate_o_acetylation|bacterial_l_carnitine_catabolism	ACCEPT
yeast/SLN1	P39928	559292	GO:0007234	osmosensory signaling via phosphorelay pathway	ARBA:ARBA00084941	NO_MODULE	False				coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|scer_hog1_cascade|sphingolipid_de_novo_synthesis|two_component_relay	ACCEPT
yeast/SNO1	Q03144	559292	GO:0008614	pyridoxine metabolic process	ARBA:ARBA00084501	NO_MODULE	False				arginine_biosynthesis|de_novo_pyrimidine_synthesis|glutamate_glutamine_ammonia_hub|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|vitamin_b6_plp_metabolism	MODIFY
yeast/SNO2	P53823	559292	GO:0008614	pyridoxine metabolic process	ARBA:ARBA00084501	NO_MODULE	False				arginine_biosynthesis|de_novo_pyrimidine_synthesis|glutamate_glutamine_ammonia_hub|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|vitamin_b6_plp_metabolism	MODIFY
yeast/SNZ1	Q03148	559292	GO:0008615	pyridoxine biosynthetic process	ARBA:ARBA00084504	NO_MODULE	False				vitamin_b6_plp_metabolism	MODIFY
yeast/SOD1	P00445	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
yeast/SPE3	Q12074	559292	GO:0006596	polyamine biosynthetic process	ARBA:ARBA00026615	ENTAILED	True	polyamine_metabolism		polyamine_metabolism:srm_activity	methionine_biosynthesis	ACCEPT
yeast/SPE4	Q12455	559292	GO:0006596	polyamine biosynthetic process	ARBA:ARBA00026615	ENTAILED	True	polyamine_metabolism		polyamine_metabolism:sms_activity|polyamine_metabolism:spe4_activity|polyamine_metabolism:srm_activity	methionine_biosynthesis	ACCEPT
yeast/SPT16	P32558	559292	GO:0006366	transcription by RNA polymerase II	ARBA:ARBA00028158	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors	KEEP_AS_NON_CORE
yeast/SPT16	P32558	559292	GO:0040029	epigenetic regulation of gene expression	ARBA:ARBA00033485	NO_MODULE	False				cobalamin_intracellular_processing|complex_i_assembly_factors	KEEP_AS_NON_CORE
yeast/SSA1	P10591	559292	GO:0006457	protein folding	ARBA:ARBA00027200	ENTAILED	True	cct_chaperonin_folding		cct_chaperonin_folding:prefoldin_complex_chaperone	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/SSA1	P10591	559292	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ARBA:ARBA00087312	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/SSA1	P10591	559292	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSA1	P10591	559292	GO:0051170	import into nucleus	ARBA:ARBA00026529	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/SSA2	P10592	559292	GO:0006457	protein folding	ARBA:ARBA00027200	ENTAILED	True	cct_chaperonin_folding		cct_chaperonin_folding:prefoldin_complex_chaperone	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/SSA2	P10592	559292	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ARBA:ARBA00087312	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/SSA2	P10592	559292	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ARBA:ARBA00026940	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSA2	P10592	559292	GO:0051170	import into nucleus	ARBA:ARBA00026529	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSA3	P09435	559292	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ARBA:ARBA00087312	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/SSA3	P09435	559292	GO:0030163	protein catabolic process	ARBA:ARBA00027403	NOT_ENTAILED	False	heparan_sulfate_lysosomal_degradation|keratan_chondroitin_sulfate_lysosomal_degradation			bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSA4	P22202	559292	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation	ARBA:ARBA00087312	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	MODIFY
yeast/SSB1	P11484	559292	GO:0000054	ribosomal subunit export from nucleus	ARBA:ARBA00090246	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|phosphorylase_kinase_comple	KEEP_AS_NON_CORE
yeast/SSB1	P11484	559292	GO:0006364	rRNA processing	ARBA:ARBA00028153	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|phosphorylase_kinase_comple	KEEP_AS_NON_CORE
yeast/SSB1	P11484	559292	GO:0006450	regulation of translational fidelity	ARBA:ARBA00027186	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|phosphorylase_kinase_comple	KEEP_AS_NON_CORE
yeast/SSB1	P11484	559292	GO:0006452	translational frameshifting	ARBA:ARBA00085751	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|phosphorylase_kinase_comple	KEEP_AS_NON_CORE
yeast/SSB1	P11484	559292	GO:0051083	'de novo' cotranslational protein folding	ARBA:ARBA00088074	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism|phosphorylase_kinase_comple	ACCEPT
yeast/SSB2	P40150	559292	GO:0000054	ribosomal subunit export from nucleus	ARBA:ARBA00090246	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSB2	P40150	559292	GO:0006364	rRNA processing	ARBA:ARBA00028153	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSB2	P40150	559292	GO:0006450	regulation of translational fidelity	ARBA:ARBA00027186	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSB2	P40150	559292	GO:0006452	translational frameshifting	ARBA:ARBA00085751	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	KEEP_AS_NON_CORE
yeast/SSB2	P40150	559292	GO:0051083	'de novo' cotranslational protein folding	ARBA:ARBA00088074	NO_MODULE	False				bacterial_nucleotide_excision_repair|cct_chaperonin_folding|coenzyme_q10_biosynthesis|heat_shock_response|linc_complex|mitochondrial_complex_ii|mitochondrial_complex_iii|mitochondrial_complex_v|muth_independent_mismatch_repair|peroxisome-lifecycle|phenylacetate_catabolism	ACCEPT
yeast/SSK1	Q07084	559292	GO:0006950	response to stress	ARBA:ARBA00026300	ENTAILED	False	scer_hog1_cascade		scer_hog1_cascade:ssk1_activity|scer_hog1_cascade:ste50_adaptor_activity	dolichol_phosphate_sugar_donor_supply|sphingolipid_de_novo_synthesis|two_component_relay	MODIFY
yeast/SSK1	Q07084	559292	GO:0071467	cellular response to pH	ARBA:ARBA00092243	NO_MODULE	False				dolichol_phosphate_sugar_donor_supply|scer_hog1_cascade|sphingolipid_de_novo_synthesis|two_component_relay	KEEP_AS_NON_CORE
yeast/SSK2	P53599	559292	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map3k_activity	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|scer_hog1_cascade|scer_mating_fus3_cascade|sphi	ACCEPT
yeast/SSK22	P25390	559292	GO:0038066	p38MAPK cascade	ARBA:ARBA00088051	ENTAILED	True	p38_cascade		p38_cascade:p38_map3k_activity	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|scer_hog1_cascade|scer_mating_fus3_cascade|sphi	ACCEPT
yeast/STE11	P23561	559292	GO:0071507	pheromone response MAPK cascade	ARBA:ARBA00092461	ENTAILED	True	scer_mating_fus3_cascade		scer_mating_fus3_cascade:fus3_map3k_activity	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|heat_shock_response|intraflagellar_transport|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|metaphase_anaphase_transition_and_mitotic_exit|p38_cascade|peptidoglycan_recycling|scer_hog1_casca	ACCEPT
yeast/STE7	P06784	559292	GO:0071507	pheromone response MAPK cascade	ARBA:ARBA00092461	ENTAILED	True	scer_mating_fus3_cascade		scer_mating_fus3_cascade:fus3_map2k_activity	coenzyme_a_biosynthesis|erk5_cascade|g2_m_transition|jnk_cascade|kinase_phosphatase_toggle|mapk_relay|p38_cascade|peptidoglycan_recycling|scer_hog1_cascade|sphingolipid_de_novo_synthesis	ACCEPT
yeast/STR2	P47164	559292	GO:0050667	homocysteine metabolic process	ARBA:ARBA00089512	ENTAILED	True	fungal_sulfur_amino_acid_transsulfuration		fungal_sulfur_amino_acid_transsulfuration:cystathionine_gamma_synthase_activity	methionine_biosynthesis	KEEP_AS_NON_CORE
yeast/STT4	P37297	559292	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			coenzyme_a_biosynthesis|peptidoglycan_recycling|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
yeast/SUR1	P33300	559292	GO:0006676	mannosyl diphosphorylinositol ceramide metabolic process	ARBA:ARBA00087413	NO_MODULE	False				sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/SUR1	P33300	559292	GO:0006688	glycosphingolipid biosynthetic process	ARBA:ARBA00043439	NOT_ENTAILED	True	glycosphingolipid_biosynthesis			sphingolipid_de_novo_synthesis	ACCEPT
yeast/SWE1	P32944	559292	GO:0051447	negative regulation of meiotic cell cycle	ARBA:ARBA00088857	NO_MODULE	False				coenzyme_a_biosynthesis|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/SWI2	P22082	559292	GO:0006302	double-strand break repair	ARBA:ARBA00027906	MODULE_INCOMPLETE	False	bacterial_recbcd_end_resection	bacterial_recbcd_end_resection:recb_resection	bacterial_recbcd_end_resection:recc_scaffold_activity	bacterial_nucleotide_excision_repair|coenzyme_q10_biosynthesis|complex_i_assembly_factors|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenylacetate_catabolism|phosphotyrosi	ACCEPT
yeast/SWI2	P22082	559292	GO:0045815	transcription initiation-coupled chromatin remodeling	ARBA:ARBA00086456	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenyla	ACCEPT
yeast/SWI2	P22082	559292	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|coenzyme_q10_biosynthesis|complex_i_assembly_factors|ergosterol_biosynthesis|linc_complex|metaphase_anaphase_transition_and_mitotic_exit|muth_independent_mismatch_repair|oligosaccharyltransferase_complex|peroxisome-lifecycle|phenyla	ACCEPT
yeast/SWI3	P32591	559292	GO:0006338	chromatin remodeling	ARBA:ARBA00027994	NO_MODULE	False				bacterial_recbcd_end_resection	ACCEPT
yeast/SWI3	P32591	559292	GO:0006355	regulation of DNA-templated transcription	ARBA:ARBA00028138	NO_MODULE	False				bacterial_recbcd_end_resection	ACCEPT
yeast/SWI6	P09959	559292	GO:0045944	positive regulation of transcription by RNA polymerase II	ARBA:ARBA00027996	NO_MODULE	False				bacterial_recbcd_end_resection|g1_s_transition|heat_shock_response	ACCEPT
yeast/TEM1	P38987	559292	GO:0035556	intracellular signal transduction	ARBA:ARBA00026887	ENTAILED	False	gtpase_switch		gtpase_switch:gtpase_activity	chylomicron_assembly_secretion|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	ACCEPT
yeast/TEM1	P38987	559292	GO:0090068	positive regulation of cell cycle process	ARBA:ARBA00029176	NO_MODULE	False				chylomicron_assembly_secretion|gtpase_switch|metaphase_anaphase_transition_and_mitotic_exit|mitochondrial_dynamics|phenylacetate_catabolism|propionyl_coa_catabolism|urease_biogenesis_urea_hydrolysis	ACCEPT
yeast/THI80	P35202	559292	GO:0042723	thiamine-containing compound metabolic process	ARBA:ARBA00028583	ENTAILED	False	eukaryotic_thiamine_biosynthesis		eukaryotic_thiamine_biosynthesis:tpk_activity	sphingolipid_de_novo_synthesis	MODIFY
yeast/TIM10	P87108	559292	GO:0045039	protein insertion into mitochondrial inner membrane	ARBA:ARBA00029129	NO_MODULE	False				cobalamin_intracellular_processing|complex_iv_assembly_factors	ACCEPT
yeast/TIM9	O74700	559292	GO:0045039	protein insertion into mitochondrial inner membrane	ARBA:ARBA00029129	NO_MODULE	False				cobalamin_intracellular_processing	ACCEPT
yeast/TOR1	P35169	559292	GO:0006995	cellular response to nitrogen starvation	ARBA:ARBA00034562	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TOR1	P35169	559292	GO:0010507	negative regulation of autophagy	ARBA:ARBA00043537	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TOR1	P35169	559292	GO:0031929	TOR signaling	ARBA:ARBA00086602	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TOR1	P35169	559292	GO:0042254	ribosome biogenesis	ARBA:ARBA00026817	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TOR1	P35169	559292	GO:1905356	regulation of snRNA pseudouridine synthesis	ARBA:ARBA00087228	NO_MODULE	False				coenzyme_a_biosynthesis|complex_i_assembly_factors|g2_m_transition|gpcr_camp_pka_signaling|gpcr_plc_calcium_pkc_signaling|intraflagellar_transport|kinase_phosphatase_toggle|metaphase_anaphase_transition_and_mitotic_exit|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/TRX1	P22217	559292	GO:0000011	vacuole inheritance	ARBA:ARBA00088811	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	ACCEPT
yeast/TRX1	P22217	559292	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ARBA:ARBA00027177	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	KEEP_AS_NON_CORE
yeast/TRX1	P22217	559292	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	ARBA:ARBA00086884	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	KEEP_AS_NON_CORE
yeast/TRX1	P22217	559292	GO:0042144	vacuole fusion, non-autophagic	ARBA:ARBA00085976	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	ACCEPT
yeast/TRX1	P22217	559292	GO:0045454	cell redox homeostasis	ARBA:ARBA00085337	ENTAILED	True	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:cytosolic_trx_activity	aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|oligosaccharyltransferase_complex	ACCEPT
yeast/TRX2	P22803	559292	GO:0000011	vacuole inheritance	ARBA:ARBA00088811	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	ACCEPT
yeast/TRX2	P22803	559292	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	ARBA:ARBA00027177	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	KEEP_AS_NON_CORE
yeast/TRX2	P22803	559292	GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	ARBA:ARBA00086884	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	KEEP_AS_NON_CORE
yeast/TRX2	P22803	559292	GO:0042144	vacuole fusion, non-autophagic	ARBA:ARBA00085976	NO_MODULE	False				aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|glutathione_thioredoxin_redox_systems|oligosaccharyltransferase_complex	ACCEPT
yeast/TRX2	P22803	559292	GO:0045454	cell redox homeostasis	ARBA:ARBA00085337	ENTAILED	True	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:cytosolic_trx_activity	aps_dependent_assimilatory_sulfate_reduction|complex_i_assembly_factors|complex_iv_assembly_factors|oligosaccharyltransferase_complex	ACCEPT
yeast/TSA1	P34760	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|heat_shock_response|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TSA1	P34760	559292	GO:0034605	cellular response to heat	ARBA:ARBA00026567	ENTAILED	True	heat_shock_response		heat_shock_response:hsp12_6_shsp	complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/TSA1	P34760	559292	GO:0045454	cell redox homeostasis	ARBA:ARBA00085337	ENTAILED	True	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:ahp1_activity|glutathione_thioredoxin_redox_systems:bcp_prx_activity|glutathione_thioredoxin_redox_systems:gpx_like_prx_activity|glutathione_thioredoxin_redox_systems:typical_2cys_prx_activity	complex_i_assembly_factors|heat_shock_response|sphingolipid_de_novo_synthesis	ACCEPT
yeast/TSA1	P34760	559292	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems|heat_shock_response|sphingolipid_de_novo_synthesis	KEEP_AS_NON_CORE
yeast/TSA2	Q04120	559292	GO:0034599	cellular response to oxidative stress	ARBA:ARBA00027632	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	ACCEPT
yeast/TSA2	Q04120	559292	GO:0034605	cellular response to heat	ARBA:ARBA00026567	NOT_ENTAILED	True	heat_shock_response			complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	KEEP_AS_NON_CORE
yeast/TSA2	Q04120	559292	GO:0045454	cell redox homeostasis	ARBA:ARBA00085337	ENTAILED	True	glutathione_thioredoxin_redox_systems		glutathione_thioredoxin_redox_systems:ahp1_activity|glutathione_thioredoxin_redox_systems:bcp_prx_activity|glutathione_thioredoxin_redox_systems:gpx_like_prx_activity|glutathione_thioredoxin_redox_systems:typical_2cys_prx_activity	complex_i_assembly_factors	ACCEPT
yeast/TSA2	Q04120	559292	GO:0050821	protein stabilization	ARBA:ARBA00033884	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	KEEP_AS_NON_CORE
yeast/TSA2	Q04120	559292	GO:0051260	protein homooligomerization	ARBA:ARBA00089314	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	KEEP_AS_NON_CORE
yeast/TSA2	Q04120	559292	GO:0051291	protein heterooligomerization	ARBA:ARBA00089325	NO_MODULE	False				complex_i_assembly_factors|glutathione_thioredoxin_redox_systems	KEEP_AS_NON_CORE
yeast/URA10	P30402	559292	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ARBA:ARBA00086394	NO_MODULE	False				de_novo_pyrimidine_synthesis	ACCEPT
yeast/URA10	P30402	559292	GO:0046132	pyrimidine ribonucleoside biosynthetic process	ARBA:ARBA00091020	NO_MODULE	False				de_novo_pyrimidine_synthesis	MODIFY
yeast/URA2	P07259	559292	GO:1901137	carbohydrate derivative biosynthetic process	ARBA:ARBA00026302	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:aspartate_carbamoyltransferase_activity|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_glutaminase_component|de_novo_pyrimidine_synthesis:carbamoyl_phosphate_synthetase_component	arginine_biosynthesis|glutamate_glutamine_ammonia_hub|phenylacetate_catabolism|tetrahydrofolate_biosynthesis|urea_cycle|vitamin_b6_plp_metabolism	MARK_AS_OVER_ANNOTATED
yeast/URA5	P13298	559292	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	ARBA:ARBA00086394	NO_MODULE	False				de_novo_pyrimidine_synthesis	ACCEPT
yeast/URA5	P13298	559292	GO:0046132	pyrimidine ribonucleoside biosynthetic process	ARBA:ARBA00091020	NO_MODULE	False				de_novo_pyrimidine_synthesis	MODIFY
yeast/URK1	P27515	559292	GO:0008655	pyrimidine-containing compound salvage	ARBA:ARBA00084547	MODULE_INCOMPLETE	True	pyrimidine_salvage	pyrimidine_salvage:cmp_kinase_step	pyrimidine_salvage:uridine_kinase_activity	coenzyme_a_biosynthesis|peptidoglycan_recycling|sphingolipid_de_novo_synthesis	ACCEPT
yeast/VIP1	Q06685	559292	GO:0030643	intracellular phosphate ion homeostasis	ARBA:ARBA00086651	NO_MODULE	False				coenzyme_a_biosynthesis|myo_inositol_and_inositol_phosphate_biosynthesis|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/VIP1	Q06685	559292	GO:0032958	inositol phosphate biosynthetic process	ARBA:ARBA00087455	MODULE_INCOMPLETE	True	myo_inositol_and_inositol_phosphate_biosynthesis	myo_inositol_and_inositol_phosphate_biosynthesis:myo_inositol_synthesis	myo_inositol_and_inositol_phosphate_biosynthesis:ip6k_activity|myo_inositol_and_inositol_phosphate_biosynthesis:ppip5k_activity	coenzyme_a_biosynthesis|phenylacetate_catabolism|sphingolipid_de_novo_synthesis	ACCEPT
yeast/VPS34	P22543	559292	GO:0033554	cellular response to stress	ARBA:ARBA00028184	NOT_ENTAILED	False	bacterial_nucleotide_excision_repair|bacterial_recbcd_end_resection|bacterial_ruvabc_holliday_junction_processing|heat_shock_response|jnk_cascade			coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|phosphoinositide_biosynthesis|sphingolipid_de_novo_synthesis	MARK_AS_OVER_ANNOTATED
yeast/VPS45	P38932	559292	GO:0006886	intracellular protein transport	ARBA:ARBA00027179	NO_MODULE	False					ACCEPT
yeast/VPS45	P38932	559292	GO:0031338	regulation of vesicle fusion	ARBA:ARBA00086104	NO_MODULE	False					ACCEPT
yeast/XPT1	P47165	559292	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	ARBA:ARBA00027608	NOT_ENTAILED	False	de_novo_purine_synthesis|purine_nucleotide_interconversion			purine_salvage_and_catabolism	ACCEPT
yeast/XPT1	P47165	559292	GO:0106380	purine ribonucleotide salvage	ARBA:ARBA00090487	NO_MODULE	False				purine_salvage_and_catabolism	ACCEPT
yeast/YDJ1	P25491	559292	GO:0070585	protein localization to mitochondrion	ARBA:ARBA00028355	NO_MODULE	False				heat_shock_response|mitochondrial_complex_ii	ACCEPT
yeast/YNK1	P36010	559292	GO:0009142	nucleoside triphosphate biosynthetic process	ARBA:ARBA00033837	ENTAILED	False	de_novo_pyrimidine_synthesis		de_novo_pyrimidine_synthesis:udp_ndp_kinase_activity	coenzyme_a_biosynthesis|dntp_de_novo_synthesis|purine_nucleotide_interconversion|sphingolipid_de_novo_synthesis	ACCEPT
yeast/YPD1	Q07688	559292	GO:0007234	osmosensory signaling via phosphorelay pathway	ARBA:ARBA00084941	NO_MODULE	False				coenzyme_a_biosynthesis|kinase_phosphatase_toggle|peptidoglycan_recycling|scer_hog1_cascade|sphingolipid_de_novo_synthesis|two_component_relay	ACCEPT