entryType: UniProtKB unreviewed (TrEMBL)

scientificName: Caenorhabditis elegans

source: EMBL

source: Proteomes

lineage: Eukaryota Metazoa Ecdysozoa Nematoda Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis

proteinExistence: 1: Evidence at protein level

value: DNA replication licensing factor mcm-4

source: WormBase

Proteomics identification

source: PeptideAtlas

category: Technical term

citationType: journal article

authors:
Sulson J.E.
Waterston R.

database: PubMed

database: DOI

title: Genome sequence of the nematode C. elegans: a platform for investigating biology.

journal: Science

referencePositions: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

value: Bristol N2

type: STRAIN

database: EMBL

key: ProteinId

key: Status

key: MoleculeType

database: RefSeq

key: NucleotideSequenceId

database: AlphaFoldDB

key: Description

database: SMR

database: PeptideAtlas

database: GeneID

database: AGR

database: CTD

database: WormBase

key: GeneId

key: GeneName

database: HOGENOM

database: OrthoDB

database: Proteomes

key: Component

value: Chromosome I

database: Bgee

key: ExpressionPatterns

value: Expressed in germ line (C elegans) and 4 other cell types or tissues

database: ExpressionAtlas

value: baseline and differential

database: Pfam

key: EntryName

key: MatchStatus


scientificName: Drosophila melanogaster

commonName: Fruit fly

lineage: Eukaryota Metazoa Ecdysozoa Arthropoda Altocrustacea Allotriocarida Hexapoda Insecta Pterygota Neoptera Eumetabola Endopterygota Aparaglossata Panorpida Diptera Brachycera Muscomorpha Ephydroidea Drosophilidae Drosophila Sophophora

proteinExistence: 3: Inferred from homology

source: PROSITE

value: Peptidase S1 domain-containing protein

source: FlyBase

source: ARBA

value: Belongs to the peptidase S1 family. CLIP subfamily

commentType: SIMILARITY

source: PROSITE-ProRule

value: Lacks conserved residue(s) required for the propagation of feature annotation

commentType: CAUTION

type: Signal

modifier: EXACT

source: SAM

type: Chain

description: Peptidase S1 domain-containing protein

type: Domain

description: Peptidase S1

type: Disulfide bond

Disulfide bond

category: PTM

Signal

category: Domain

authors:
Adams M.D.
Celniker S.E.
Holt R.A.
Evans C.A.
Gocayne J.D.
Amanatides P.G.
Scherer S.E.
Li P.W.
Hoskins R.A.
Galle R.F.
George R.A.
Lewis S.E.
Richards S.
Ashburner M.
Henderson S.N.
Sutton G.G.
Wortman J.R.
Yandell M.D.
Zhang Q.
Chen L.X.
Brandon R.C.
Rogers Y.H.
Blazej R.G.
Champe M.
Pfeiffer B.D.
Wan K.H.
Doyle C.
Baxter E.G.
Helt G.
Nelson C.R.
Gabor G.L.
Abril J.F.
Agbayani A.
An H.J.
Andrews-Pfannkoch C.
Baldwin D.
Ballew R.M.
Basu A.
Baxendale J.
Bayraktaroglu L.
Beasley E.M.
Beeson K.Y.
Benos P.V.
Berman B.P.
Bhandari D.
Bolshakov S.
Borkova D.
Botchan M.R.
Bouck J.
Brokstein P.
Brottier P.
Burtis K.C.
Busam D.A.
Butler H.
Cadieu E.
Center A.
Chandra I.
Cherry J.M.
Cawley S.
Dahlke C.
Davenport L.B.
Davies P.
de Pablos B.
Delcher A.
Deng Z.
Mays A.D.
Dew I.
Dietz S.M.
Dodson K.
Doup L.E.
Downes M.
Dugan-Rocha S.
Dunkov B.C.
Dunn P.
Durbin K.J.
Evangelista C.C.
Ferraz C.
Ferriera S.
Fleischmann W.
Fosler C.
Gabrielian A.E.
Garg N.S.
Gelbart W.M.
Glasser K.
Glodek A.
Gong F.
Gorrell J.H.
Gu Z.
Guan P.
Harris M.
Harris N.L.
Harvey D.
Heiman T.J.
Hernandez J.R.
Houck J.
Hostin D.
Houston K.A.
Howland T.J.
Wei M.H.
Ibegwam C.
Jalali M.
Kalush F.
Karpen G.H.
Ke Z.
Kennison J.A.
Ketchum K.A.
Kimmel B.E.
Kodira C.D.
Kraft C.
Kravitz S.
Kulp D.
Lai Z.
Lasko P.
Lei Y.
Levitsky A.A.
Li J.
Li Z.
Liang Y.
Lin X.
Liu X.
Mattei B.
McIntosh T.C.
McLeod M.P.
McPherson D.
Merkulov G.
Milshina N.V.
Mobarry C.
Morris J.
Moshrefi A.
Mount S.M.
Moy M.
Murphy B.
Murphy L.
Muzny D.M.
Nelson D.L.
Nelson D.R.
Nelson K.A.
Nixon K.
Nusskern D.R.
Pacleb J.M.
Palazzolo M.
Pittman G.S.
Pan S.
Pollard J.
Puri V.
Reese M.G.
Reinert K.
Remington K.
Saunders R.D.
Scheeler F.
Shen H.
Shue B.C.
Siden-Kiamos I.
Simpson M.
Skupski M.P.
Smith T.
Spier E.
Spradling A.C.
Stapleton M.
Strong R.
Sun E.
Svirskas R.
Tector C.
Turner R.
Venter E.
Wang A.H.
Wang X.
Wang Z.Y.
Wassarman D.A.
Weinstock G.M.
Weissenbach J.
Williams S.M.
WoodageT
Worley K.C.
Wu D.
Yang S.
Yao Q.A.
Ye J.
Yeh R.F.
Zaveri J.S.
Zhan M.
Zhang G.
Zhao Q.
Zheng L.
Zheng X.H.
Zhong F.N.
Zhong W.
Zhou X.
Zhu S.
Zhu X.
Smith H.O.
Gibbs R.A.
Myers E.W.
Rubin G.M.
Venter J.C.

database: PubMed

title: The genome sequence of Drosophila melanogaster.

value: Berkeley

authors:
Celniker S.E.
Wheeler D.A.
Kronmiller B.
Carlson J.W.
Halpern A.
Patel S.
Adams M.
Champe M.
Dugan S.P.
Frise E.
Hodgson A.
George R.A.
Hoskins R.A.
Laverty T.
Muzny D.M.
Nelson C.R.
Pacleb J.M.
Park S.
Pfeiffer B.D.
Richards S.
Sodergren E.J.
Svirskas R.
Tabor P.E.
Wan K.
Stapleton M.
Sutton G.G.
Venter C.
Weinstock G.
Scherer S.E.
Myers E.W.
Gibbs R.A.
Rubin G.M.

title: Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.

journal: Genome Biol.

authors:
Misra S.
Crosby M.A.
Mungall C.J.
Matthews B.B.
Campbell K.S.
Hradecky P.
Huang Y.
Kaminker J.S.
Millburn G.H.
Prochnik S.E.
Smith C.D.
Tupy J.L.
Whitfied E.J.
Bayraktaroglu L.
Berman B.P.
Bettencourt B.R.
Celniker S.E.
de Grey A.D.
Drysdale R.A.
Harris N.L.
Richter J.
Russo S.
Schroeder A.J.
Shu S.Q.
Stapleton M.
Yamada C.
Ashburner M.
Gelbart W.M.
Rubin G.M.
Lewis S.E.

title: Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.

authors:
Kaminker J.S.
Bergman C.M.
Kronmiller B.
Carlson J.
Svirskas R.
Patel S.
Frise E.
Wheeler D.A.
Lewis S.E.
Rubin G.M.
Ashburner M.
Celniker S.E.

title: The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.

authors:
Hoskins R.A.
Smith C.D.
Carlson J.W.
Carvalho A.B.
Halpern A.
Kaminker J.S.
Kennedy C.
Mungall C.J.
Sullivan B.A.
Sutton G.G.
Yasuhara J.C.
Wakimoto B.T.
Myers E.W.
Celniker S.E.
Rubin G.M.
Karpen G.H.

title: Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.

authors:
Quesneville H.
Bergman C.M.
Andrieu O.
Autard D.
Nouaud D.
Ashburner M.
Anxolabehere D.

title: Combined evidence annotation of transposable elements in genome sequences.

journal: PLoS Comput. Biol.

authors:
Smith C.D.
Shu S.
Mungall C.J.
Karpen G.H.

title: The Release 5.1 annotation of Drosophila melanogaster heterochromatin.

authors:
Hoskins R.A.
Carlson J.W.
Kennedy C.
Acevedo D.
Evans-Holm M.
Frise E.
Wan K.H.
Park S.
Mendez-Lago M.
Rossi F.
Villasante A.
Dimitri P.
Karpen G.H.
Celniker S.E.

title: Sequence finishing and mapping of Drosophila melanogaster heterochromatin.

authors:
Matthews B.B.
Dos Santos G.
Crosby M.A.
Emmert D.B.
St Pierre S.E.
Gramates L.S.
Zhou P.
Schroeder A.J.
Falls K.
Strelets V.
Russo S.M.
Gelbart W.M.

title: Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.

authors:
Crosby M.A.
Gramates L.S.
Dos Santos G.
Matthews B.B.
St Pierre S.E.
Zhou P.
Schroeder A.J.
Falls K.
Emmert D.B.
Russo S.M.
Gelbart W.M.

title: Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.

authors:
Hoskins R.A.
Carlson J.W.
Wan K.H.
Park S.
Mendez I.
Galle S.E.
Booth B.W.
Pfeiffer B.D.
George R.A.
Svirskas R.
Krzywinski M.
Schein J.
Accardo M.C.
Damia E.
Messina G.
Mendez-Lago M.
de Pablos B.
Demakova O.V.
Andreyeva E.N.
Boldyreva L.V.
Marra M.
Carvalho A.B.
Dimitri P.
Villasante A.
Zhimulev I.F.
Rubin G.M.
Karpen G.H.
Celniker S.E.

title: The Release 6 reference sequence of the Drosophila melanogaster genome.

value: Expressed in larva and 4 other cell types or tissues


proteinExistence: 4: Predicted

value: Larval cuticle protein 3, isoform B

value: III

value: LcpIII

Cuticle

category: Cellular component

database: DOI

value: Expressed in larva and 5 other cell types or tissues

value: CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED


source: Pfam

value: Cyclin N-terminal domain-containing protein

value: Belongs to the cyclin family

description: Cyclin N-terminal

type: Region

description: Disordered

description: Disordered

description: Disordered

description: Disordered

type: Compositional bias

description: Basic residues

description: Low complexity

description: Polar residues

description: Low complexity

description: Polar residues

Cell cycle

category: Biological process

value: Cyclin E associated events during G1/S transition

value: Cyclin A:Cdk2-associated events at S phase entry

value: Expressed in enterocyte of anterior adult midgut epithelium in digestive tract and 253 other cell types or tissues

value: CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN


value: Chymotrypsin

commentType: CATALYTIC ACTIVITY

name: Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.

description: Chymotrypsin

description: Peptidase S1

description: Peptidase S1

type: Active site

description: Charge relay system

description: Charge relay system

description: Charge relay system

Calcium

category: Ligand

Hydrolase

category: Molecular function

value: Expressed in arthropod fat body and 3 other cell types or tissues


value: COP9 signalosome complex subunit 5

value: JadBp

value: quo

commentType: SUBCELLULAR LOCATION

value: Cytoplasm

value: Nucleus

value: Belongs to the peptidase M67A family. CSN5 subfamily

description: MPN

type: Motif

description: JAMM motif

type: Binding site

database: ChEBI

note: catalytic

value: Expressed in cleaving embryo and 105 other cell types or tissues

value: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED


value: Uncharacterized protein

value: Berkeley

journal: G3 (Bethesda)


type: Transmembrane

description: Helical

value: Expressed in ovary and 8 other cell types or tissues


source: RuleBase

value: Nucleoside diphosphate kinase

value: awd

value: AWD

value: Awd

value: clone 2.27

value: clone 2.28

value: e(shi)A

value: eshiA

value: K-pn

value: Kpn

value: NDKB

value: NDPK

name: a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP

database: Rhea

name: a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP

commentType: COFACTOR

value: Belongs to the NDK family

description: Nucleoside diphosphate kinase

description: Nucleoside diphosphate kinase-like

source: SMART

description: Pros-phosphohistidine intermediate

value: Expressed in egg cell and 303 other cell types or tissues

value: F:nucleoside diphosphate kinase activity

value: Nucleoside diphosphate kinase-like domain


scientificName: Mus musculus

commonName: Mouse

source: Ensembl

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus

value: Signal peptidase complex subunit 2 homolog (S. cerevisiae)

source: MGI

description: Disordered

description: Gly residues

description: Basic and acidic residues

description: Basic residues

Proteomics identification

source: ProteomicsDB

authors:
Trinidad J.C.
Specht C.G.
Thalhammer A.
Schoepfer R.
Burlingame A.L.

title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

journal: Mol. Cell. Proteomics

referencePositions: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

source: PubMed

authors:
Church D.M.
Goodstadt L.
Hillier L.W.
Zody M.C.
Goldstein S.
She X.
Bult C.J.
Agarwala R.
Cherry J.L.
DiCuccio M.
Hlavina W.
Kapustin Y.
Meric P.
Maglott D.
Birtle Z.
Marques A.C.
Graves T.
Zhou S.
Teague B.
Potamousis K.
Churas C.
Place M.
Herschleb J.
Runnheim R.
Forrest D.
Amos-Landgraf J.
Schwartz D.C.
Cheng Z.
Lindblad-Toh K.
Eichler E.E.
Ponting C.P.

title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

journal: PLoS Biol.

authors:
Church D.M.
Schneider V.A.
Graves T.
Auger K.
Cunningham F.
Bouk N.
Chen H.C.
Agarwala R.
McLaren W.M.
Ritchie G.R.
Albracht D.
Kremitzki M.
Rock S.
Kotkiewicz H.
Kremitzki C.
Wollam A.
Trani L.
Fulton L.
Fulton R.
Matthews L.
Whitehead S.
Chow W.
Torrance J.
Dunn M.
Harden G.
Threadgold G.
Wood J.
Collins J.
Heath P.
Griffiths G.
Pelan S.
Grafham D.
Eichler E.E.
Weinstock G.
Mardis E.R.
Wilson R.K.
Howe K.
Flicek P.
Hubbard T.

title: Modernizing reference genome assemblies.

citationType: submission

submissionDatabase: UniProtKB

database: AlphaFoldDB

database: jPOST

database: ProteomicsDB

database: Antibodypedia

key: antibodies

value: 125 antibodies from 21 providers

database: Ensembl

database: MGI

database: VEuPathDB

database: GeneTree

value: Chromosome 7

value: Expressed in lacrimal gland and 260 other cell types or tissues

value: baseline and differential


scientificName: Arabidopsis thaliana

commonName: Mouse-ear cress

lineage: Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis

value: FTSH protease 12

source: TAIR

value: EMBRYO DEFECTIVE 1047

value: EMBRYO DEFECTIVE 156

value: EMBRYO DEFECTIVE 36

source: Araport

value: In the C-terminal section; belongs to the peptidase M41 family

value: In the N-terminal section; belongs to the AAA ATPase family

description: Helical

description: Helical

description: AAA+ ATPase

authors:
Theologis A.
Ecker J.R.
Palm C.J.
Federspiel N.A.
Kaul S.
White O.
Alonso J.
Altafi H.
Araujo R.
Bowman C.L.
Brooks S.Y.
Buehler E.
Chan A.
Chao Q.
Chen H.
Cheuk R.F.
Chin C.W.
Chung M.K.
Conn L.
Conway A.B.
Conway A.R.
Creasy T.H.
Dewar K.
Dunn P.
Etgu P.
Feldblyum T.V.
Feng J.
Fong B.
Fujii C.Y.
Gill J.E.
Goldsmith A.D.
Haas B.
Hansen N.F.
Hughes B.
Huizar L.
Hunter J.L.
Jenkins J.
Johnson-Hopson C.
Khan S.
Khaykin E.
Kim C.J.
Koo H.L.
Kremenetskaia I.
Kurtz D.B.
Kwan A.
Lam B.
Langin-Hooper S.
Lee A.
Lee J.M.
Lenz C.A.
Li J.H.
Li Y.
Lin X.
Liu S.X.
Liu Z.A.
Luros J.S.
Maiti R.
Marziali A.
Militscher J.
Miranda M.
Nguyen M.
Nierman W.C.
Osborne B.I.
Pai G.
Peterson J.
Pham P.K.
Rizzo M.
Rooney T.
Rowley D.
Sakano H.
Salzberg S.L.
Schwartz J.R.
Shinn P.
Southwick A.M.
Sun H.
Tallon L.J.
Tambunga G.
Toriumi M.J.
Town C.D.
Utterback T.
Van Aken S.
Vaysberg M.
Vysotskaia V.S.
Walker M.
Wu D.
Yu G.
Fraser C.M.
Venter J.C.
Davis R.W.

title: Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.

journal: Nature

value: cv. Columbia

authors:
Cheng C.Y.
Krishnakumar V.
Chan A.P.
Thibaud-Nissen F.
Schobel S.
Town C.D.

title: Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.

journal: Plant J.

database: EMBL

database: RefSeq

database: SMR

value: ATP-dependent zinc metalloprotease FTSH 12, chloroplastic

value: P-loop containing nucleotide triphosphate hydrolases

value: ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 12, CHLOROPLASTIC

value: P-loop containing nucleoside triphosphate hydrolases


scientificName: Cucumis melo

commonName: Muskmelon

source: Proteomes

source: RefSeq

lineage: Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Cucurbitales Cucurbitaceae Benincaseae Cucumis

value: mitogen-activated protein kinase

name: L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)

name: L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)

value: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily

description: Protein kinase

description: Disordered

value: Stem

type: TISSUE

database: GeneID

database: KEGG

database: eggNOG

key: ToxonomicScope

value: Eukaryota

database: InParanoid

database: OrthoDB

database: Proteomes

database: GO

key: GoTerm

value: F:ATP binding

key: GoEvidenceType

value: F:MAP kinase activity

value: F:protein serine kinase activity

database: CDD


scientificName: Nicotiana tabacum

commonName: Common tobacco

lineage: Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Nicotianoideae Nicotianeae Nicotiana

value: ribonuclease P

name: Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

database: ChEBI

value: Belongs to the PPR family. P subfamily

description: PROP1-like PPR

type: Repeat

description: PPR

description: PRORP

description: Disordered

description: Low complexity

authors:
Sierro N.
Battey J.N.
Ouadi S.
Bakaher N.
Bovet L.
Willig A.
Goepfert S.
Peitsch M.C.
Ivanov N.V.

database: PubMed

database: DOI

title: The tobacco genome sequence and its comparison with those of tomato and potato.

journal: Nat. Commun.

value: Leaf

database: AlphaFoldDB

database: STRING

database: PaxDb

database: OMA

key: Fingerprint

value: Chromosome 22

value: F:ribonuclease P activity

value: P:tRNA 5'-leader removal

database: FunFam

value: Proteinaceous RNase P 2


source: EMBL

value: Nucleolar protein 4 helical domain-containing protein

description: Nucleolar protein 4 helical

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

type: Coiled coil

description: Polar residues

description: Polar residues

description: Low complexity

description: Low complexity

description: Low complexity

description: Low complexity

description: Polar residues

description: Acidic residues

description: Gly residues

authors:
Adams M.D.
Celniker S.E.
Holt R.A.
Evans C.A.
Gocayne J.D.
Amanatides P.G.
Scherer S.E.
Li P.W.
Hoskins R.A.
Galle R.F.
George R.A.
Lewis S.E.
Richards S.
Ashburner M.
Henderson S.N.
Sutton G.G.
Wortman J.R.
Yandell M.D.
Zhang Q.
Chen L.X.
Brandon R.C.
Rogers Y.H.
Blazej R.G.
Champe M.
Pfeiffer B.D.
Wan K.H.
Doyle C.
Baxter E.G.
Helt G.
Nelson C.R.
Gabor G.L.
Abril J.F.
Agbayani A.
An H.J.
Andrews-Pfannkoch C.
Baldwin D.
Ballew R.M.
Basu A.
Baxendale J.
Bayraktaroglu L.
Beasley E.M.
Beeson K.Y.
Benos P.V.
Berman B.P.
Bhandari D.
Bolshakov S.
Borkova D.
Botchan M.R.
Bouck J.
Brokstein P.
Brottier P.
Burtis K.C.
Busam D.A.
Butler H.
Cadieu E.
Center A.
Chandra I.
Cherry J.M.
Cawley S.
Dahlke C.
Davenport L.B.
Davies P.
de Pablos B.
Delcher A.
Deng Z.
Mays A.D.
Dew I.
Dietz S.M.
Dodson K.
Doup L.E.
Downes M.
Dugan-Rocha S.
Dunkov B.C.
Dunn P.
Durbin K.J.
Evangelista C.C.
Ferraz C.
Ferriera S.
Fleischmann W.
Fosler C.
Gabrielian A.E.
Garg N.S.
Gelbart W.M.
Glasser K.
Glodek A.
Gong F.
Gorrell J.H.
Gu Z.
Guan P.
Harris M.
Harris N.L.
Harvey D.
Heiman T.J.
Hernandez J.R.
Houck J.
Hostin D.
Houston K.A.
Howland T.J.
Wei M.H.
Ibegwam C.
Jalali M.
Kalush F.
Karpen G.H.
Ke Z.
Kennison J.A.
Ketchum K.A.
Kimmel B.E.
Kodira C.D.
Kraft C.
Kravitz S.
Kulp D.
Lai Z.
Lasko P.
Lei Y.
Levitsky A.A.
Li J.
Li Z.
Liang Y.
Lin X.
Liu X.
Mattei B.
McIntosh T.C.
McLeod M.P.
McPherson D.
Merkulov G.
Milshina N.V.
Mobarry C.
Morris J.
Moshrefi A.
Mount S.M.
Moy M.
Murphy B.
Murphy L.
Muzny D.M.
Nelson D.L.
Nelson D.R.
Nelson K.A.
Nixon K.
Nusskern D.R.
Pacleb J.M.
Palazzolo M.
Pittman G.S.
Pan S.
Pollard J.
Puri V.
Reese M.G.
Reinert K.
Remington K.
Saunders R.D.
Scheeler F.
Shen H.
Shue B.C.
Siden-Kiamos I.
Simpson M.
Skupski M.P.
Smith T.
Spier E.
Spradling A.C.
Stapleton M.
Strong R.
Sun E.
Svirskas R.
Tector C.
Turner R.
Venter E.
Wang A.H.
Wang X.
Wang Z.Y.
Wassarman D.A.
Weinstock G.M.
Weissenbach J.
Williams S.M.
WoodageT
Worley K.C.
Wu D.
Yang S.
Yao Q.A.
Ye J.
Yeh R.F.
Zaveri J.S.
Zhan M.
Zhang G.
Zhao Q.
Zheng L.
Zheng X.H.
Zhong F.N.
Zhong W.
Zhou X.
Zhu S.
Zhu X.
Smith H.O.
Gibbs R.A.
Myers E.W.
Rubin G.M.
Venter J.C.

title: The genome sequence of Drosophila melanogaster.

value: Berkeley

value: Expressed in T neuron T5a (Drosophila) in embryonic/larval optic lobe (Drosophila) and 100 other cell types or tissues


scientificName: Aquarana catesbeiana

commonName: American bullfrog

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Neobatrachia Ranoidea Ranidae Aquarana

source: PROSITE

value: CUB domain-containing protein

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: CUB

authors:
Hammond S.A.
Warren R.L.
Vandervalk B.P.
Kucuk E.
Khan H.
Gibb E.A.
Pandoh P.
Kirk H.
Zhao Y.
Jones M.
Mungall A.J.
Coope R.
Pleasance S.
Moore R.A.
Holt R.A.
Round J.M.
Ohora S.
Walle B.V.
Veldhoen N.
Helbing C.C.
Birol I.

title: The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA.

database: EMBL

value: Unassembled WGS sequence

value: CUB

value: Procollagen C-endopeptidase enhancer 1

value: Spermadhesin, CUB domain

database: InterPro

database: PANTHER

value: CUB DOMAIN-CONTAINING PROTEIN

value: OVOCHYMASE-RELATED

database: Pfam

database: SMART

database: SUPFAM

database: PROSITE


scientificName: Columba livia

commonName: Rock dove

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Neoaves Columbimorphae Columbiformes Columbidae Columba

value: TruB pseudouridine (Psi) synthase family member 2

value: Belongs to the pseudouridine synthase TruB family

value: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data

description: Pseudouridine synthase II N-terminal

authors:
Shapiro M.D.
Kronenberg Z.
Li C.
Domyan E.T.
Pan H.
Campbell M.
Tan H.
Huff C.D.
Hu H.
Vickrey A.I.
Nielsen S.C.
Stringham S.A.
Hu H.
Willerslev E.
Gilbert M.T.
Yandell M.
Zhang G.
Wang J.

title: Genomic diversity and evolution of the head crest in the rock pigeon.

value: Blood

database: InParanoid

database: Proteomes

database: GO

value: F:pseudouridine synthase activity

value: F:RNA binding

value: P:pseudouridine synthesis

value: P:RNA processing

value: Pseudouridine synthase

value: PSEUDOURIDINE SYNTHASE-RELATED

value: PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL


scientificName: Juglans regia

commonName: English walnut

lineage: Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fagales Juglandaceae Juglans

value: Glycosyltransferase

value: Belongs to the UDP-glycosyltransferase family

description: Glycosyltransferase N-terminal

value: Leaves

database: RefSeq

database: GeneID

database: Gramene

database: KEGG

database: OrthoDB

value: Chromosome 3

value: F:UDP-glycosyltransferase activity

database: CDD

value: Glycogen Phosphorylase B

value: GLYCOSYLTRANSFERASE

value: UDP-GLYCOSYLTRANSFERASE 73C3-RELATED

value: UDPGT


scientificName: Macaca fascicularis

commonName: Crab-eating macaque

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Cercopithecidae Cercopithecinae Macaca

value: Tetratricopeptide repeat domain 39C

value: Belongs to the TTC39 family

authors:
Warren W.
Wilson R.K.

submissionDatabase: EMBL/GenBank/DDBJ databases

database: AlphaFoldDB

database: Ensembl

database: VEuPathDB

database: GeneTree

value: Chromosome 18

database: Bgee

value: Expressed in liver and 13 other cell types or tissues

value: P:cilium assembly

value: P:otolith morphogenesis

value: Tetratricopeptide repeat domain

value: TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER

value: TETRATRICOPEPTIDE REPEAT PROTEIN 39C

value: TPR-like


scientificName: Homo sapiens

commonName: Human

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo

value: D-aminoacyl-tRNA deacylase

value: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality

commentType: FUNCTION

name: a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)

database: Rhea

database: ChEBI

name: glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)

value: Homodimer. Interacts with CDC45 and TOPBP1

commentType: SUBUNIT

value: Cytoplasm

value: Belongs to the DTD family

source: PeptideAtlas

authoringGroup: International Human Genome Sequencing Consortium

authors:
Lander E.S.
Linton L.M.
Birren B.
Nusbaum C.
Zody M.C.
Baldwin J.
Devon K.
Dewar K.
Doyle M.
FitzHugh W.
Funke R.
Gage D.
Harris K.
Heaford A.
Howland J.
Kann L.
Lehoczky J.
LeVine R.
McEwan P.
McKernan K.
Meldrim J.
Mesirov J.P.
Miranda C.
Morris W.
Naylor J.
Raymond C.
Rosetti M.
Santos R.
Sheridan A.
Sougnez C.
Stange-Thomann N.
Stojanovic N.
Subramanian A.
Wyman D.
Rogers J.
Sulston J.
Ainscough R.
Beck S.
Bentley D.
Burton J.
Clee C.
Carter N.
Coulson A.
Deadman R.
Deloukas P.
Dunham A.
Dunham I.
Durbin R.
French L.
Grafham D.
Gregory S.
Hubbard T.
Humphray S.
Hunt A.
Jones M.
Lloyd C.
McMurray A.
Matthews L.
Mercer S.
Milne S.
Mullikin J.C.
Mungall A.
Plumb R.
Ross M.
Shownkeen R.
Sims S.
Waterston R.H.
Wilson R.K.
Hillier L.W.
McPherson J.D.
Marra M.A.
Mardis E.R.
Fulton L.A.
Chinwalla A.T.
Pepin K.H.
Gish W.R.
Chissoe S.L.
Wendl M.C.
Delehaunty K.D.
Miner T.L.
Delehaunty A.
Kramer J.B.
Cook L.L.
Fulton R.S.
Johnson D.L.
Minx P.J.
Clifton S.W.
Hawkins T.
Branscomb E.
Predki P.
Richardson P.
Wenning S.
Slezak T.
Doggett N.
Cheng J.F.
Olsen A.
Lucas S.
Elkin C.
Uberbacher E.
Frazier M.
Gibbs R.A.
Muzny D.M.
Scherer S.E.
Bouck J.B.
Sodergren E.J.
Worley K.C.
Rives C.M.
Gorrell J.H.
Metzker M.L.
Naylor S.L.
Kucherlapati R.S.
Nelson D.L.
Weinstock G.M.
Sakaki Y.
Fujiyama A.
Hattori M.
Yada T.
Toyoda A.
Itoh T.
Kawagoe C.
Watanabe H.
Totoki Y.
Taylor T.
Weissenbach J.
Heilig R.
Saurin W.
Artiguenave F.
Brottier P.
Bruls T.
Pelletier E.
Robert C.
Wincker P.
Smith D.R.
Doucette-Stamm L.
Rubenfield M.
Weinstock K.
Lee H.M.
Dubois J.
Rosenthal A.
Platzer M.
Nyakatura G.
Taudien S.
Rump A.
Yang H.
Yu J.
Wang J.
Huang G.
Gu J.
Hood L.
Rowen L.
Madan A.
Qin S.
Davis R.W.
Federspiel N.A.
Abola A.P.
Proctor M.J.
Myers R.M.
Schmutz J.
Dickson M.
Grimwood J.
Cox D.R.
Olson M.V.
Kaul R.
Raymond C.
Shimizu N.
Kawasaki K.
Minoshima S.
Evans G.A.
Athanasiou M.
Schultz R.
Roe B.A.
Chen F.
Pan H.
Ramser J.
Lehrach H.
Reinhardt R.
McCombie W.R.
de la Bastide M.
Dedhia N.
Blocker H.
Hornischer K.
Nordsiek G.
Agarwala R.
Aravind L.
Bailey J.A.
Bateman A.
Batzoglou S.
Birney E.
Bork P.
Brown D.G.
Burge C.B.
Cerutti L.
Chen H.C.
Church D.
Clamp M.
Copley R.R.
Doerks T.
Eddy S.R.
Eichler E.E.
Furey T.S.
Galagan J.
Gilbert J.G.
Harmon C.
Hayashizaki Y.
Haussler D.
Hermjakob H.
Hokamp K.
Jang W.
Johnson L.S.
Jones T.A.
Kasif S.
Kaspryzk A.
Kennedy S.
Kent W.J.
Kitts P.
Koonin E.V.
Korf I.
Kulp D.
Lancet D.
Lowe T.M.
McLysaght A.
Mikkelsen T.
Moran J.V.
Mulder N.
Pollara V.J.
Ponting C.P.
Schuler G.
Schultz J.
Slater G.
Smit A.F.
Stupka E.
Szustakowski J.
Thierry-Mieg D.
Thierry-Mieg J.
Wagner L.
Wallis J.
Wheeler R.
Williams A.
Wolf Y.I.
Wolfe K.H.
Yang S.P.
Yeh R.F.
Collins F.
Guyer M.S.
Peterson J.
Felsenfeld A.
Wetterstrand K.A.
Patrinos A.
Morgan M.J.
de Jong P.
Catanese J.J.
Osoegawa K.
Shizuya H.
Choi S.
Chen Y.J.

database: PubMed

database: DOI

title: Initial sequencing and analysis of the human genome.

authors:
Deloukas P.
Matthews L.H.
Ashurst J.
Burton J.
Gilbert J.G.
Jones M.
Stavrides G.
Almeida J.P.
Babbage A.K.
Bagguley C.L.
Bailey J.
Barlow K.F.
Bates K.N.
Beard L.M.
Beare D.M.
Beasley O.P.
Bird C.P.
Blakey S.E.
Bridgeman A.M.
Brown A.J.
Buck D.
Burrill W.
Butler A.P.
Carder C.
Carter N.P.
Chapman J.C.
Clamp M.
Clark G.
Clark L.N.
Clark S.Y.
Clee C.M.
Clegg S.
Cobley V.E.
Collier R.E.
Connor R.
Corby N.R.
Coulson A.
Coville G.J.
Deadman R.
Dhami P.
Dunn M.
Ellington A.G.
Frankland J.A.
Fraser A.
French L.
Garner P.
Grafham D.V.
Griffiths C.
Griffiths M.N.
Gwilliam R.
Hall R.E.
Hammond S.
Harley J.L.
Heath P.D.
Ho S.
Holden J.L.
Howden P.J.
Huckle E.
Hunt A.R.
Hunt S.E.
Jekosch K.
Johnson C.M.
Johnson D.
Kay M.P.
Kimberley A.M.
King A.
Knights A.
Laird G.K.
Lawlor S.
Lehvaslaiho M.H.
Leversha M.
Lloyd C.
Lloyd D.M.
Lovell J.D.
Marsh V.L.
Martin S.L.
McConnachie L.J.
McLay K.
McMurray A.A.
Milne S.
Mistry D.
Moore M.J.
Mullikin J.C.
Nickerson T.
Oliver K.
Parker A.
Patel R.
Pearce T.A.
Peck A.I.
Phillimore B.J.
Prathalingam S.R.
Plumb R.W.
Ramsay H.
Rice C.M.
Ross M.T.
Scott C.E.
Sehra H.K.
Shownkeen R.
Sims S.
Skuce C.D.
Smith M.L.
Soderlund C.
Steward C.A.
Sulston J.E.
Swann M.
Sycamore N.
Taylor R.
Tee L.
Thomas D.W.
Thorpe A.
Tracey A.
Tromans A.C.
Vaudin M.
Wall M.
Wallis J.M.
Whitehead S.L.
Whittaker P.
Willey D.L.
Williams L.
Williams S.A.
Wilming L.
Wray P.W.
Hubbard T.
Durbin R.M.
Bentley D.R.
Beck S.
Rogers J.

title: The DNA sequence and comparative analysis of human chromosome 20.

title: Finishing the euchromatic sequence of the human genome.

authors:
Burkard T.R.
Planyavsky M.
Kaupe I.
Breitwieser F.P.
Burckstummer T.
Bennett K.L.
Superti-Furga G.
Colinge J.

title: Initial characterization of the human central proteome.

journal: BMC Syst. Biol.

authors:
Van Damme P.
Lasa M.
Polevoda B.
Gazquez C.
Elosegui-Artola A.
Kim D.S.
De Juan-Pardo E.
Demeyer K.
Hole K.
Larrea E.
Timmerman E.
Prieto J.
Arnesen T.
Sherman F.
Gevaert K.
Aldabe R.

title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

journal: Proc. Natl. Acad. Sci. U.S.A.

database: EMBL

database: SMR

database: MassIVE

value: Expressed in gingival epithelium and 195 other cell types or tissues


scientificName: Pan paniscus

commonName: Pygmy chimpanzee

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Pan

source: ARBA

value: Sodium-independent sulfate anion transporter

value: Solute carrier family 26 member 11

value: Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum

name: hydrogencarbonate(in) + chloride(out) = hydrogencarbonate(out) + chloride(in)

name: oxalate(in) + chloride(out) = oxalate(out) + chloride(in)

name: sulfate(in) + H(+)(in) = sulfate(out) + H(+)(out)

value: Apical cell membrane

value: Multi-pass membrane protein

value: Basolateral cell membrane

value: Lysosome membrane

value: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: STAS

authors:
Prufer K.
Munch K.
Hellmann I.
Akagi K.
Miller J.R.
Walenz B.
Koren S.
Sutton G.
Kodira C.
Winer R.
Knight J.R.
Mullikin J.C.
Meader S.J.
Ponting C.P.
Lunter G.
Higashino S.
Hobolth A.
Dutheil J.
Karakoc E.
Alkan C.
Sajjadian S.
Catacchio C.R.
Ventura M.
Marques-Bonet T.
Eichler E.E.
Andre C.
Atencia R.
Mugisha L.
Junhold J.
Patterson N.
Siebauer M.
Good J.M.
Fischer A.
Ptak S.E.
Lachmann M.
Symer D.E.
Mailund T.
Schierup M.H.
Andres A.M.
Kelso J.
Paabo S.

title: The bonobo genome compared with the chimpanzee and human genomes.

value: Expressed in adult mammalian kidney and 6 other cell types or tissues

value: F:secondary active sulfate transmembrane transporter activity


scientificName: Artemisia annua

commonName: Sweet wormwood

lineage: Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids campanulids Asterales Asteraceae Asteroideae Anthemideae Artemisiinae Artemisia

source: HAMAP-Rule

value: Translation factor GUF1 homolog, mitochondrial

value: Elongation factor 4 homolog

value: GTPase GUF1 homolog

value: Ribosomal back-translocase

value: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner

value: Mitochondrion inner membrane

value: Peripheral membrane protein

value: Matrix side

value: Belongs to the GTP-binding elongation factor family. LepA subfamily

value: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily

source: PROSITE-ProRule

value: Lacks conserved residue(s) required for the propagation of feature annotation

value: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data

description: Tr-type G

description: Disordered

description: Polar residues

authors:
Shen Q.
Zhang L.
Liao Z.
Wang S.
Yan T.
Shi P.
Liu M.
Fu X.
Pan Q.
Wang Y.
Lv Z.
Lu X.
Zhang F.
Jiang W.
Ma Y.
Chen M.
Hao X.
Li L.
Tang Y.
Lv G.
Zhou Y.
Sun X.
Brodelius P.E.
Rose J.K.C.
Tang K.

title: The genome of Artemisia annua provides insight into the evolution of Asteraceae family and artemisinin biosynthesis.

journal: Mol. Plant

value: cv. Huhao1

value: Leaf

value: Elongation Factor G (Translational Gtpase), domain 3

value: P-loop containing nucleotide triphosphate hydrolases

value: TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC

value: P-loop containing nucleoside triphosphate hydrolases


value: Vomeronasal 2, receptor 73

value: Cell membrane

value: Multi-pass membrane protein

source: SAM

description: Receptor ligand binding region

source: Pfam

description: GPCR family 3 nine cysteines

database: AGR

database: MGI

database: Proteomes

value: Chromosome 7

database: ExpressionAtlas

value: baseline

database: GO

value: C:plasma membrane


scientificName: Triticum aestivum

commonName: Wheat

source: EnsemblPlants

lineage:
Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
Liliopsida
Poales
Poaceae
BOP clade
Pooideae
Triticodae
Triticeae
Triticinae
Triticum

value: PNPLA domain-containing protein

value: Possesses non-specific lipolytic acyl hydrolase (LAH) activity. Hydrolyzes phospholipids as well as galactolipids. May play a role in disease resistance

value: Belongs to the patatin family

description: PNPLA

value: cv. Chinese Spring

database: AlphaFoldDB

database: STRING

database: PaxDb

database: EnsemblPlants

database: Gramene

database: OMA

database: OrthoDB

value: Chromosome 3D

value: F:lipase activity

value: P:lipid metabolic process

value: Cytosolic phospholipase A2 catalytic domain

database: InterPro

database: PANTHER

value: OS08G0376550 PROTEIN

value: XYLOSE ISOMERASE

database: SUPFAM


source: Google

value: GHMP kinase N-terminal domain-containing protein

description: GHMP kinase N-terminal

description: GHMP kinase C-terminal

database: SMR

database: UniPathway

key: RectionId

value: Chromosome 6A

value: F:ATP binding

value: P:isopentenyl diphosphate biosynthetic process, mevalonate pathway

value: WITH PUTATIVE URIDYL PYROPHOSPHORYLASE-RELATED


value: JmjC domain-containing protein

value: Nucleus

value: Belongs to the JARID1 histone demethylase family

description: F-box

description: JmjC

description: Disordered

description: Basic residues

database: ChEBI

database: RefSeq

key: ProteinId

database: GeneID

value: ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD


scientificName: Equus caballus

commonName: Horse

source: Ensembl

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Perissodactyla Equidae Equus

value: Vesicle-associated membrane protein-associated protein A

source: VGNC

value: VAPA

value: Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. STARD3-VAPA interaction enables cholesterol transfer from the ER to endosomes. Via interaction with WDR44 participates in neosynthesized protein export. In addition, recruited to the plasma membrane through OSBPL3 binding. The OSBPL3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking

value: Cell junction, tight junction

value: Cell membrane

value: Single-pass type IV membrane protein

value: Endoplasmic reticulum membrane

value: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family

description: Helical

description: MSP

description: Disordered

description: Basic and acidic residues

authoringGroup: Broad Institute Genome Sequencing Platform

authoringGroup: Broad Institute Whole Genome Assembly Team

authors:
Wade C.M.
Giulotto E.
Sigurdsson S.
Zoli M.
Gnerre S.
Imsland F.
Lear T.L.
Adelson D.L.
Bailey E.
Bellone R.R.
Bloecker H.
Distl O.
Edgar R.C.
Garber M.
Leeb T.
Mauceli E.
MacLeod J.N.
Penedo M.C.T.
Raison J.M.
Sharpe T.
Vogel J.
Andersson L.
Antczak D.F.
Biagi T.
Binns M.M.
Chowdhary B.P.
Coleman S.J.
Della Valle G.
Fryc S.
Guerin G.
Hasegawa T.
Hill E.W.
Jurka J.
Kiialainen A.
Lindgren G.
Liu J.
Magnani E.
Mickelson J.R.
Murray J.
Nergadze S.G.
Onofrio R.
Pedroni S.
Piras M.F.
Raudsepp T.
Rocchi M.
Roeed K.H.
Ryder O.A.
Searle S.
Skow L.
Swinburne J.E.
Syvaenen A.C.
Tozaki T.
Valberg S.J.
Vaudin M.
White J.R.
Zody M.C.
Lander E.S.
Lindblad-Toh K.

database: PubMed

database: DOI

title: Genome sequence, comparative analysis, and population genetics of the domestic horse.

value: Thoroughbred

database: Ensembl

database: KEGG

value: Expressed in muscle tissue and 23 other cell types or tissues

value: vesicle-associated membrane protein-associated protein A isoform X1

value: VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN A


value: Interleukin 1 receptor associated kinase 3

value: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily

description: Protein kinase

description: Disordered

description: Disordered

database: AlphaFoldDB

database: VGNC

database: GeneTree

database: Proteomes

value: Chromosome 6

database: Bgee

value: Expressed in liver and 21 other cell types or tissues

database: GO

value: F:ATP binding

value: F:protein kinase activity

value: P:signal transduction

database: FunFam

value: Death Domain, Fas

value: Phosphorylase Kinase, domain 1

value: INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3

database: Pfam

value: Death


value: Calcyphosine like

value: CAPSL

description: EF-hand

description: EF-hand

description: EF-hand

database: FunCoup

key: Number of interactors

database: STRING

database: PaxDb

database: InParanoid

value: Chromosome 21

value: Expressed in epithelium of bronchus and 5 other cell types or tissues

value: F:calcium ion binding

value: EF-hand

database: InterPro

value: Ca-bind

database: PANTHER

value: CALCYPHOSIN

value: CALCYPHOSIN-LIKE PROTEIN

database: PRINTS


value: WD repeat containing planar cell polarity effector

value: WDPCP

value: Cell membrane

value: Cytoplasm, cytoskeleton, cilium axoneme

value: Belongs to the WD repeat fritz family

database: PubMed

database: DOI

value: Thoroughbred

database: Ensembl

value: Chromosome 15

value: Expressed in oviduct epithelium and 22 other cell types or tissues

value: C:plasma membrane

value: Frtz

value: WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG

database: SUPFAM


scientificName: Arachis hypogaea

commonName: Peanut

lineage:
Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
eudicotyledons
Gunneridae
Pentapetalae
rosids
fabids
Fabales
Fabaceae
Papilionoideae
50 kb inversion clade
dalbergioids sensu lato
Dalbergieae
Pterocarpus clade
Arachis

value: Cellulose synthase domain-containing protein

value: Golgi apparatus membrane

value: Multi-pass membrane protein

value: Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like D subfamily

value: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Cellulose synthase

description: Disordered

description: Low complexity

description: Polar residues

source: PIRSR

database: ChEBI

title: Sequencing of cultivated peanut Arachis hypogaea provides insights into genome evolution and oil improvement.

value: F:cellulose synthase (UDP-forming) activity

value: Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A

value: Zinc/RING finger domain, C3HC4 (zinc finger)


value: Succinate dehydrogenase complex assembly factor 2

source: MGI

value: Mitochondrion matrix

source: ProteomicsDB

title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

database: AlphaFoldDB

database: SMR

database: Antibodypedia

value: 57 antibodies from 24 providers

database: AGR

database: MGI

database: VEuPathDB

database: GeneTree

database: Proteomes

value: Chromosome 19

value: Expressed in otic placode and 261 other cell types or tissues

database: ExpressionAtlas

value: baseline and differential

value: C:mitochondrial matrix

value: P:negative regulation of canonical Wnt signaling pathway

value: P:negative regulation of epithelial to mesenchymal transition

value: Succinate dehydrogenase assembly factor 2, mitochondrial

value: Flavinator of succinate dehydrogenase

value: SDH

value: PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL

value: SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL


scientificName: Callorhinchus milii

commonName: Ghost shark

source: Proteomes

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Chondrichthyes Holocephali Chimaeriformes Callorhinchidae Callorhinchus

value: RRM domain-containing protein

value: Nucleus

value: Belongs to the ESRP family

description: RRM

authors:
Venkatesh B.
Kirkness E.F.
Loh Y.H.
Halpern A.L.
Lee A.P.
Johnson J.
Dandona N.
Viswanathan L.D.
Tay A.
Venter J.C.
Strausberg R.L.
Brenner S.

title: Ancient noncoding elements conserved in the human genome.

title: Survey sequencing and comparative analysis of the elephant shark (Callorhinchus milii) genome.

authoringGroup: International Elephant Shark Genome Sequencing Consortium

authors:
Venkatesh B.
Lee A.P.
Ravi V.
Maurya A.K.
Lian M.M.
Swann J.B.
Ohta Y.
Flajnik M.F.
Sutoh Y.
Kasahara M.
Hoon S.
Gangu V.
Roy S.W.
Irimia M.
Korzh V.
Kondrychyn I.
Lim Z.W.
Tay B.H.
Tohari S.
Kong K.W.
Ho S.
Lorente-Galdos B.
Quilez J.
Marques-Bonet T.
Raney B.J.
Ingham P.W.
Tay A.
Hillier L.W.
Minx P.
Boehm T.
Wilson R.K.
Brenner S.
Warren W.C.

title: Elephant shark genome provides unique insights into gnathostome evolution.

database: FunCoup

database: STRING

database: InParanoid

database: OMA

value: Unassembled WGS sequence

database: GO

value: F:RNA binding

database: CDD

database: FunFam

value: Epithelial splicing regulatory protein 1

value: epithelial splicing regulatory protein 1 isoform X1

value: Ribonuclease H-like superfamily/Ribonuclease H

database: InterPro

value: ESRP


value: Coiled-coil and C2 domain containing 2A

source: SMART

description: Disordered

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Basic and acidic residues

description: Basic residues

description: Acidic residues

description: Polar residues

database: PubMed

database: DOI

value: Thoroughbred

database: Ensembl

database: VGNC

value: Chromosome 3

database: Bgee

value: Expressed in oviduct epithelium and 21 other cell types or tissues

value: baseline

value: C2 domain

value: COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 2A


value: Asparagine-linked glycosylation protein 5 homolog

name: a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP

database: Rhea

database: ChEBI

directionType: left-to-right

value: Protein modification; protein glycosylation

commentType: PATHWAY

value: Endoplasmic reticulum membrane

value: Single-pass membrane protein

value: Belongs to the glycosyltransferase 2 family

description: Glycosyltransferase 2-like

database: AlphaFoldDB

value: Chromosome 17

value: Expressed in trophoblast and 23 other cell types or tissues

value: C:endoplasmic reticulum membrane

value: Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A


value: Voltage-dependent L-type calcium channel subunit beta-3

value: Calcium channel voltage-dependent subunit beta 3

value: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation

value: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1C) and the ancillary subunits CACNB3 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio. Interacts with CACNA2D4. Interacts with FASLG. Interacts with CBARP; prevents the interaction of CACNB3 with the alpha subunit CACNA1C thereby negatively regulating the activity of the corresponding calcium channel

value: Cytoplasm

value: Belongs to the calcium channel beta subunit family

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Polar residues

description: Basic and acidic residues

database: GeneTree

database: Proteomes

value: Chromosome 6

value: Expressed in prefrontal cortex and 22 other cell types or tissues

value: C:L-type voltage-gated calcium channel complex

value: F:high voltage-gated calcium channel activity

value: Voltage-dependent L-type calcium channel subunit beta-2

value: P-loop containing nucleotide triphosphate hydrolases

value: VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT

value: P-loop containing nucleoside triphosphate hydrolases


scientificName: Takifugu rubripes

commonName: Japanese pufferfish

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Eupercaria Tetraodontiformes Tetradontoidea Tetraodontidae Takifugu

value: Growth arrest-specific 7a

description: F-BAR

authors:
Kai W.
Kikuchi K.
Tohari S.
Chew A.K.
Tay A.
Fujiwara A.
Hosoya S.
Suetake H.
Naruse K.
Brenner S.
Suzuki Y.
Venkatesh B.

title: Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals.

journal: Genome Biol. Evol.

database: RefSeq

database: FunCoup

database: GeneID

database: KEGG

database: CTD

database: OrthoDB

value: Chromosome 5

value: C:clathrin-coated pit

value: C:clathrin-coated vesicle

value: C:plasma membrane

value: P:clathrin coat assembly

value: P:clathrin-dependent endocytosis

value: P:neuron projection morphogenesis

value: growth arrest-specific protein 7 isoform X2

value: Arfaptin homology (AH) domain/BAR domain

database: PANTHER

value: GROWTH ARREST-SPECIFIC PROTEIN 7

value: PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1

database: Pfam


scientificName: Aedes aegypti

commonName: Yellowfever mosquito

source: EnsemblMetazoa

lineage: Eukaryota Metazoa Ecdysozoa Arthropoda Altocrustacea Allotriocarida Hexapoda Insecta Pterygota Neoptera Eumetabola Endopterygota Aparaglossata Panorpida Diptera Nematocera Culicoidea Culicidae Culicinae Aedini Aedes Stegomyia

value: Uncharacterized protein

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Low complexity

description: Low complexity

description: Polar residues

description: Polar residues

description: Low complexity

authoringGroup: Aedes aegypti Genome Working Group (AGWG)

title: Aedes aegypti genome working group (AGWG) sequencing and assembly.

database: EnsemblMetazoa

value: Chromosome 3

database: CDD

value: C2 domain

value: GTPase Activation - p120gap, domain 1

database: InterPro

value: C2 domain (Calcium/lipid-binding domain, CaLB)


scientificName: Drosophila pseudoobscura pseudoobscura

commonName: Fruit fly

source: RefSeq

lineage: Eukaryota Metazoa Ecdysozoa Arthropoda Altocrustacea Allotriocarida Hexapoda Insecta Pterygota Neoptera Eumetabola Endopterygota Aparaglossata Panorpida Diptera Brachycera Muscomorpha Ephydroidea Drosophilidae Drosophila Sophophora

value: Probable E3 ubiquitin-protein ligase HERC3 isoform X3

value: Whole body

value: Chromosome X

value: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

value: BTK-BINDING PROTEIN-RELATED

database: PRINTS

value: RCCNDNSATION

database: SUPFAM

database: PROSITE


value: long-chain-acyl-CoA dehydrogenase

name: (11Z)-eicosenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,11Z)-eicosadienoyl-CoA + reduced [electron-transfer flavoprotein]

database: Rhea

database: ChEBI

name: (11Z)-octadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,11Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z)-decenoyl-CoA(4-) + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z)-decadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z,7Z)-decadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z,7Z)-decatrienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z,7Z,10Z)-hexadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z,7Z,10Z)-hexadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (4Z,7Z,10Z,13Z)-hexadecatetraenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,4Z,7Z,10Z,13Z)-hexadecapentaenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (5Z)-dodecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-dodecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (5Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (5Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (5Z,8Z)-tetradecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z,8Z)-tetradecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (5Z,8Z,11Z)-tetradecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z,8Z,11Z)-tetradecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z)-dodecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z)-dodecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z)-octadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z,9Z)-dodecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z,9Z)-dodecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,6Z,9Z,12Z,15Z)-octadecapentaenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (7Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (7Z)-octadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (7Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (7Z,10Z)-hexadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z,10Z)-hexadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z,10Z,13Z)-hexadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

name: (9Z)-eicosenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z)-eicosadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (9Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]

name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z,15Z)-octadecatetraenoyl-CoA + reduced [electron-transfer flavoprotein]

name: a long-chain 2,3-saturated fatty acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]

name: dodecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein]

name: eicosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein]

name: octadecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-octadecenoyl-CoA + reduced [electron-transfer flavoprotein]

name: oxidized [electron-transfer flavoprotein] + (9Z)-octadecenoyl-CoA + H(+) = (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

name: oxidized [electron-transfer flavoprotein] + hexadecanoyl-CoA + H(+) = (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein]

name: tetradecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-tetradecenoyl-CoA + reduced [electron-transfer flavoprotein]

value: Belongs to the acyl-CoA dehydrogenase family

description: Acyl-CoA dehydrogenase/oxidase N-terminal

description: Acyl-CoA dehydrogenase/oxidase middle

description: Acyl-CoA dehydrogenase/oxidase C-terminal

description: Disordered

authors:
Muzny D.M.
Scherer S.E.
Kaul R.
Wang J.
Yu J.
Sudbrak R.
Buhay C.J.
Chen R.
Cree A.
Ding Y.
Dugan-Rocha S.
Gill R.
Gunaratne P.
Harris R.A.
Hawes A.C.
Hernandez J.
Hodgson A.V.
Hume J.
Jackson A.
Khan Z.M.
Kovar-Smith C.
Lewis L.R.
Lozado R.J.
Metzker M.L.
Milosavljevic A.
Miner G.R.
Morgan M.B.
Nazareth L.V.
Scott G.
Sodergren E.
Song X.Z.
Steffen D.
Wei S.
Wheeler D.A.
Wright M.W.
Worley K.C.
Yuan Y.
Zhang Z.
Adams C.Q.
Ansari-Lari M.A.
Ayele M.
Brown M.J.
Chen G.
Chen Z.
Clendenning J.
Clerc-Blankenburg K.P.
Chen R.
Chen Z.
Davis C.
Delgado O.
Dinh H.H.
Dong W.
Draper H.
Ernst S.
Fu G.
Gonzalez-Garay M.L.
Garcia D.K.
Gillett W.
Gu J.
Hao B.
Haugen E.
Havlak P.
He X.
Hennig S.
Hu S.
Huang W.
Jackson L.R.
Jacob L.S.
Kelly S.H.
Kube M.
Levy R.
Li Z.
Liu B.
Liu J.
Liu W.
Lu J.
Maheshwari M.
Nguyen B.V.
Okwuonu G.O.
Palmeiri A.
Pasternak S.
Perez L.M.
Phelps K.A.
Plopper F.J.
Qiang B.
Raymond C.
Rodriguez R.
Saenphimmachak C.
Santibanez J.
Shen H.
Shen Y.
Subramanian S.
Tabor P.E.
Verduzco D.
Waldron L.
Wang J.
Wang J.
Wang Q.
Williams G.A.
Wong G.K.
Yao Z.
Zhang J.
Zhang X.
Zhao G.
Zhou J.
Zhou Y.
Nelson D.
Lehrach H.
Reinhardt R.
Naylor S.L.
Yang H.
Olson M.
Weinstock G.
Gibbs R.A.

title: The DNA sequence, annotation and analysis of human chromosome 3.

value: Expressed in upper arm skin and 178 other cell types or tissues

value: F:long-chain fatty acyl-CoA dehydrogenase activity

value: acyl-CoA dehydrogenase family member 9, mitochondrial

value: very long-chain specific acyl-CoA dehydrogenase, mitochondrial

value: Very long-chain-specific acyl-CoA dehydrogenase, mitochondrial

value: Acyl-CoA dehydrogenase/oxidase, N-terminal domain

value: Butyryl-CoA Dehydrogenase, subunit A, domain 2

value: Butyryl-CoA Dehydrogenase, subunit A, domain 3

value: COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL

value: Acyl-CoA dehydrogenase C-terminal domain-like


scientificName: Zea mays

commonName: Maize

lineage:
Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
Liliopsida
Poales
Poaceae
PACMAD clade
Panicoideae
Andropogonodae
Andropogoneae
Tripsacinae
Zea

value: PGG domain-containing protein

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: PGG

description: PGG

description: Disordered

description: Polar residues

authors:
Hufford M.B.
Seetharam A.S.
Woodhouse M.R.
Chougule K.M.
Ou S.
Liu J.
Ricci W.A.
Guo T.
Olson A.
Qiu Y.
Della Coletta R.
Tittes S.
Hudson A.I.
Marand A.P.
Wei S.
Lu Z.
Wang B.
Tello-Ruiz M.K.
Piri R.D.
Wang N.
Kim D.W.
Zeng Y.
O'Connor C.H.
Li X.
Gilbert A.M.
Baggs E.
Krasileva K.V.
Portwood J.L. II
Cannon E.K.S.
Andorf C.M.
Manchanda N.
Snodgrass S.J.
Hufnagel D.E.
Jiang Q.
Pedersen S.
Syring M.L.
Kudrna D.A.
Llaca V.
Fengler K.
Schmitz R.J.
Ross-Ibarra J.
Yu J.
Gent J.I.
Hirsch C.N.
Ware D.
Dawe R.K.

database: PubMed

database: DOI

title: De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes.

value: cv. B73

database: AlphaFoldDB

database: EnsemblPlants

database: Gramene

database: InParanoid

database: Proteomes

value: Chromosome 9

database: ExpressionAtlas

value: baseline and differential

value: CASKIN

value: OS06G0286146 PROTEIN


scientificName: Mytilus galloprovincialis

commonName: Mediterranean mussel

source: EMBL

lineage: Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Bivalvia Autobranchia Pteriomorphia Mytilida Mytiloidea Mytilidae Mytilinae Mytilus

value: Reverse transcriptase domain-containing protein

value: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data

description: Reverse transcriptase

authors:
Alioto T.
Alioto T.

database: EMBL

key: Status

key: MoleculeType

database: OrthoDB

value: Unassembled WGS sequence

value: HIV Type 1 Reverse Transcriptase, subunit A, domain 1

database: PANTHER

value: REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN

value: RIBONUCLEASE H

database: Pfam

value: DNA/RNA polymerases


value: Myotubularin-related protein 9

source: ARBA

value: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily

description: Myotubularin phosphatase

source: PROSITE

key: Description

database: GO

value: F:protein phosphatase binding

value: P:negative regulation of autophagy

database: InterPro

value: Myotubularin

value: MYOTUBULARIN-RELATED

value: Myotub-related

value: (Phosphotyrosine protein) phosphatases II


scientificName: Abrus precatorius

commonName: Indian licorice

lineage:
Eukaryota
Viridiplantae
Streptophyta
Embryophyta
Tracheophyta
Spermatophyta
Magnoliopsida
eudicotyledons
Gunneridae
Pentapetalae
rosids
fabids
Fabales
Fabaceae
Papilionoideae
50 kb inversion clade
NPAAA clade
indigoferoid/millettioid clade
Abreae
Abrus

value: Uncharacterized protein LOC113860185

description: J

description: Disordered

description: Disordered

description: Pro residues

description: Basic and acidic residues

description: Polar residues

description: Basic residues

description: Basic and acidic residues

authors:
Hovde B.T.
Daligault H.E.
Hanschen E.R.
Kunde Y.A.
Johnson M.B.
Starkenburg S.R.
Johnson S.L.

title: Detection of Abrin-Like and Prepropulchellin-Like Toxin Genes and Transcripts Using Whole Genome Sequencing and Full-Length Transcript Sequencing of Abrus precatorius.

journal: Toxins

value: Young leaves

database: RefSeq

key: NucleotideSequenceId

database: GeneID

database: KEGG

value: Unplaced

database: CDD

value: DnaJ

value: DnaJ domain

value: CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN

value: J DOMAIN-CONTAINING PROTEIN

database: SMART

database: SUPFAM

value: Chaperone J-domain


scientificName: Balaenoptera musculus

commonName: Blue whale

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Whippomorpha Cetacea Mysticeti Balaenopteridae Balaenoptera

source: PROSITE-ProRule

value: Serine/threonine-protein

name: L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)

database: Rhea

database: ChEBI

name: L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)

value: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

description: Protein kinase

description: Disordered

description: Polar residues

description: Proton acceptor

value: Epidermis and Blubber

value: F:cyclin-dependent protein serine/threonine kinase activity


scientificName: Coturnix japonica

commonName: Japanese quail

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Galliformes Phasianidae Perdicinae Coturnix

value: PAM

name: a [peptide]-C-terminal (2S)-2-hydroxyglycine = a [peptide]-C-terminal amide + glyoxylate

name: a [peptide]-C-terminal glycine + 2 L-ascorbate + O2 = a [peptide]-C-terminal (2S)-2-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O

value: Binds 2 Cu(2+) ions per subunit.

value: Binds one Zn(2+) ion per subunit.

value: Cytoplasmic vesicle, secretory vesicle membrane

value: Single-pass membrane protein

value: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family

value: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family

source: SAM

description: Helical

description: Copper type II ascorbate-dependent monooxygenase N-terminal

description: Copper type II ascorbate-dependent monooxygenase C-terminal

description: NHL

description: NHL

description: NHL

description: NHL

description: Disordered

description: Acidic residues

description: Pro residues

description: N-linked (GlcNAc...) asparagine

authoringGroup: International Coturnix japonica Genome Analysis Consortium

authors:
Warren W.
Burt D.W.
Antin P.B.
Lanford R.
Gros J.
Wilson R.K.

value: Peptidyl-glycine alpha-amidating monooxygenase B

value: peptidyl-glycine alpha-amidating monooxygenase isoform X1

value: Copper type II, ascorbate-dependent monooxygenase, N-terminal domain


scientificName: Gadus morhua

commonName: Atlantic cod

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Zeiogadaria Gadariae Gadiformes Gadoidei Gadidae Gadus

value: Rab-GAP TBC domain-containing protein

description: Rab-GAP TBC

description: Disordered

description: Disordered

description: Disordered

description: Low complexity

description: Pro residues

database: AlphaFoldDB

database: Ensembl

key: GeneId

database: GeneTree

value: Chromosome 17

value: C:cytoplasmic vesicle

value: F:GTPase activator activity

value: F:small GTPase binding

value: P:vesicle-mediated transport

database: FunFam

value: Putative TBC1 domain family member 14

value: TBC1 domain family member 14

value: putative rabgap domain of human tbc1 domain family member 14 like domains

value: Ypt/Rab-GAP domain of gyp1p, domain 1

value: Ypt/Rab-GAP domain of gyp1p, domain 3


scientificName: Piliocolobus tephrosceles

commonName: Ugandan red Colobus

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Cercopithecidae Colobinae Piliocolobus

value: Olfactomedin like 2A

value: Secreted

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Olfactomedin-like

description: Disordered

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Polar residues

description: Low complexity

database: CTD

database: Proteomes

key: Component

value: Unplaced

value: C:extracellular region

value: P:signal transduction

value: OLFACTOMEDIN-LIKE PROTEIN 2A

value: OLFACTOMEDIN-RELATED

value: OLF

database: PROSITE


scientificName: Canis lupus familiaris

commonName: Dog

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Carnivora Caniformia Canidae Canis

source: RuleBase

value: Metal transporter

value: Cell membrane

value: Multi-pass membrane protein

value: Belongs to the ACDP family

description: Metal transporter

description: Helical

description: Helical

description: Helical

description: Helical

description: CNNM transmembrane

description: CBS

authors:
Eory L.
Zhang W.
Schoenebeck J.

title: Long-read based genome assembly of a Labrador retriever dog.

value: Labrador retriever

value: Boxer

value: F:magnesium ion transmembrane transporter activity

value: F:sodium ion transmembrane transporter activity

value: P:intracellular monoatomic cation homeostasis

value: Putative metal transporter CNNM3 isoform 2


scientificName: Rattus norvegicus

commonName: Rat

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus

value: Myotubularin-related protein 12

value: Inactive phosphatidylinositol 3-phosphatase 12

source: RGD

value: Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis

value: Heterodimer with lipid phosphatase MTM1. Heterodimer with lipid phosphatase MTMR2

value: Cytoplasm, myofibril, sarcomere

value: Sarcoplasmic reticulum

value: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily

description: Myotubularin-related protein 12

description: Myotubularin phosphatase

description: Disordered

description: Basic residues

description: Polar residues

source: PeptideAtlas

authors:
Doris P.A.
Kalbfleisch T.
Li K.
Howe K.
Wood J.

title: GRCr8: a new rat reference genome assembly contstructed from accurate long reads and long range scaffolding.

value: Brown Norway

database: RGD

key: GeneName

value: Chromosome 2

database: ExpressionAtlas

key: ExpressionPatterns

value: baseline and differential

database: GO

value: C:sarcoplasmic reticulum

value: Myotubularin related protein 12

value: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

value: (Phosphotyrosine protein) phosphatases II


source: Ensembl

value: Inactive tyrosine-protein kinase 7

value: Protein-tyrosine kinase 7

value: Pseudo tyrosine kinase receptor 7

value: Tyrosine-protein kinase-like 7

value: Inactive tyrosine kinase involved in the Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathways. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Does not bind ATP

name: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)

value: Interacts with CTNNB1

value: Cell junction

value: Cell membrane

value: Single-pass type I membrane protein

value: Belongs to the protein kinase superfamily. Tyr protein kinase family

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Helical

description: Ig-like

description: Ig-like

description: Ig-like

description: Ig-like

description: Ig-like

description: Ig-like

description: Ig-like

description: Protein kinase

description: Disordered

description: Disordered

description: Proton acceptor

value: F:non-membrane spanning protein tyrosine kinase activity

value: P:establishment of epithelial cell apical/basal polarity

value: P:positive regulation of canonical Wnt signaling pathway

value: P:positive regulation of neuron projection development

value: Putative inactive tyrosine-protein kinase 7


scientificName: Xenopus tropicalis

commonName: Western clawed frog

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Amphibia Batrachia Anura Pipoidea Pipidae Xenopodinae Xenopus Silurana

value: Gastrula zinc finger protein XlCGF17.1-like

source: Xenbase

value: May be involved in transcriptional regulation

value: Nucleus

value: Belongs to the krueppel C2H2-type zinc-finger protein family

description: Disordered

description: Polar residues

value: Nigerian

value: Liver and blood

database: RefSeq

database: GeneID

database: AGR

database: Xenbase

database: OMA

database: OrthoDB

value: F:DNA-binding transcription factor activity, RNA polymerase II-specific

value: F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

value: P:regulation of transcription by RNA polymerase II

value: OOCYTE ZINC FINGER PROTEIN XLCOF7.1-LIKE


value: Serine/threonine-protein

database: Rhea

database: ChEBI

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

description: Protein kinase

description: AGC-kinase C-terminal

description: Disordered

description: Basic and acidic residues

description: Basic and acidic residues

description: Proton acceptor

database: KEGG

value: F:protein serine/threonine kinase activity


scientificName: Danio rerio

commonName: Zebrafish

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Ostariophysi Cypriniformes Danionidae Danioninae Danio

value: Auxilin

value: DnaJ homolog subfamily C member 6

source: ZFIN

value: Forms a complex composed of HSPA8, CLTC and DNAJC6. Interacts with HSPA8/HSC70 in an ATP-dependent manner; this interaction stimulates the HSPA8's ATPase activity. Interacts with CLTC; this interaction produces a local change in heavy-chain contacts, creating a detectable global distortion of the clathrin coat. Interacts with AP2A2. Interacts with DNM1(GTP-bound form); this interaction allows clathrin-coated vesicle (CCV) formation at the plasma membrane

value: Cytoplasmic vesicle, clathrin-coated vesicle

description: Phosphatase tensin-type

description: C2 tensin-type

description: J

description: Disordered

description: Acidic residues

description: Low complexity

description: Basic and acidic residues

description: Low complexity

description: Low complexity

description: Gly residues

description: Low complexity

description: Low complexity

description: Polar residues

description: Low complexity

description: Phosphocysteine intermediate

value: Tuebingen

value: putative tyrosine-protein phosphatase auxilin isoform X2

value: Protein tyrosine phosphatase superfamily

value: (Phosphotyrosine protein) phosphatases II

value: C2 domain (Calcium/lipid-binding domain, CaLB)


scientificName: Equus caballus

commonName: Horse

lineage: Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Perissodactyla Equidae Equus

name: [DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)

value: Component of the CDK-activating kinase (CAK) complex, consisting of CDK7, cyclin-H/CCNH and MAT1, which is a master regulator of CDK activity. CAK binds to both free CDK2 and cyclin-bound CDK2, with a higher affinity for the cyclin-bound form. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor. The CAK complex binds to p53/TP53 in response to DNA damage. Interacts with CDK2, SF1/NR5A1, PUF60 and PRKCI. Interacts with HINT1

value: Nucleus

value: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily

description: Protein kinase

description: Proton acceptor

source: PIRSR

value: C:transcription factor TFIIH core complex

value: F:cyclin-dependent protein serine/threonine kinase activity

value: F:RNA polymerase II CTD heptapeptide repeat S5 kinase activity

value: P:positive regulation of transcription by RNA polymerase II

value: P:regulation of G1/S transition of mitotic cell cycle

value: P:transcription initiation at RNA polymerase II promoter


value: Gem-associated protein 5

value: Cytoplasm

value: Nucleus, gem

value: Nucleus, nucleoplasm

value: Belongs to the WD repeat gemin-5 family

description: WD

description: Gem-associated protein 5 first beta-propeller

source: Pfam

description: WD

description: Gem-associated protein 5 second beta-propeller

description: WD

description: Gem-associated protein 5 TPR

description: Gem-associated protein 5 RBS

description: Disordered

description: Disordered

description: Polar residues

description: Polar residues

database: PubMed

database: DOI

value: Thoroughbred

value: YVTN repeat-like/Quinoprotein amine dehydrogenase


source: Proteomes

value: Overlapping with the m-AAA protease 1 homolog

value: Homooligomer

value: Mitochondrion inner membrane

value: Single-pass membrane protein

value: Belongs to the peptidase M48 family

description: Helical

description: Peptidase M48

database: AlphaFoldDB

database: Ensembl

database: GeneTree

value: Chromosome 2

value: baseline

value: C:mitochondrial inner membrane

value: P:negative regulation of mitochondrial fusion

value: P:positive regulation of apoptotic process

value: P:protein quality control for misfolded or incompletely synthesized proteins

value: metalloendopeptidase OMA1, mitochondrial isoform X1

value: Metalloproteases ('zincins'), catalytic domain


value: Shieldin complex subunit 2

description: Shieldin complex subunit 2 first OB fold

description: Shieldin complex subunit 2 second OB fold

description: Shieldin complex subunit 2 C-terminal

description: Disordered

description: Basic and acidic residues

database: Proteomes

value: Chromosome 1

database: InterPro

key: EntryName

database: PANTHER

value: SHIELDIN COMPLEX SUBUNIT 2

key: MatchStatus

database: Pfam


value: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation

value: Interacts with SRC. Interacts with LCK when tyrosine phosphorylated

value: Cytoplasm

description: PH

description: PH

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Acidic residues

description: Low complexity

description: Basic and acidic residues

description: Low complexity

value: Thoroughbred

database: GO

value: Actin filament-associated protein 1-like 2 isoform 1

value: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

value: ACTIN FILAMENT-ASSOCIATED PROTEIN 1 FAMILY MEMBER

value: ACTIN FILAMENT-ASSOCIATED PROTEIN 1-LIKE 2


value: Aldehyde dehydrogenase family 7 member A1

value: Betaine aldehyde dehydrogenase

name: (E)-4-hydroxynon-2-enal + NAD(+) + H2O = (E)-4-hydroxynon-2-enoate + NADH + 2 H(+)

name: (E)-non-2-enal + NAD(+) + H2O = (E)-non-2-enoate + NADH + 2 H(+)

name: (S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+)

name: an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)

name: betaine aldehyde + NAD(+) + H2O = glycine betaine + NADH + 2 H(+)

name: hexanal + NAD(+) + H2O = hexanoate + NADH + 2 H(+)

name: malonaldehyde + NAD(+) + H2O = 3-oxopropanoate + NADH + 2 H(+)

name: nonanal + NAD(+) + H2O = nonanoate + NADH + 2 H(+)

name: octanal + NAD(+) + H2O = octanoate + NADH + 2 H(+)

value: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1

value: Belongs to the aldehyde dehydrogenase family

description: Aldehyde dehydrogenase

value: F:betaine-aldehyde dehydrogenase (NAD+) activity

value: F:L-aminoadipate-semialdehyde dehydrogenase [NAD(P)+] activity

value: Aldehyde Dehydrogenase, Chain A, domain 1

value: Aldehyde Dehydrogenase, Chain A, domain 2


value: Astrocytic phosphoprotein PEA-15

value: 15 kDa phosphoprotein enriched in astrocytes

description: DED

database: RefSeq

database: GeneID

database: CTD

value: Chromosome 5

database: ExpressionAtlas

value: baseline

value: P:MAPK cascade

value: P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

database: CDD

database: FunFam

value: astrocytic phosphoprotein PEA-15 isoform X1

value: Death Domain, Fas

value: ASTROCYTIC PHOSPHOPROTEIN PEA-15

value: DED DOMAIN-CONTAINING PROTEIN


value: Protein EFR3 homolog A

value: Protein EFR3-like

value: Component of a phosphatidylinositol 4-kinase (PI4K) complex, composed of PI4KA, EFR3 (EFR3A or EFR3B), TTC7 (TTC7A or TTC7B) and HYCC (HYCC1 or HYCC2)

value: Cell membrane

value: Lipid-anchor

value: Belongs to the EFR3 family

description: EFR3-like ARM-repeat

value: Thoroughbred

value: Chromosome 9

value: C:plasma membrane

value: EFR3 homolog A (S. cerevisiae)

value: Leucine-rich Repeat Variant

value: ARM-like

value: PROTEIN EFR3 HOMOLOG A

value: PROTEIN EFR3 HOMOLOG CMP44E

database: SUPFAM

value: ARM repeat


value: Heat shock 70 kDa protein 4

value: Interacts with TJP1/ZO-1

value: Cytoplasm

value: Belongs to the heat shock protein 70 family

description: HYOU1-like C-terminal

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Basic and acidic residues

description: Basic and acidic residues

database: PubMed

value: Chromosome 14

value: baseline

value: F:ATP binding

value: F:ATP hydrolysis activity

value: Heat shock protein 70 (HSP70)-4, putative

value: Substrate Binding Domain Of DNAk, Chain A, domain 1

value: Heat shock protein 70kD (HSP70), C-terminal subdomain

value: Heat shock protein 70kD (HSP70), peptide-binding domain


value: Serine/threonine-protein phosphatase 4 regulatory subunit 4

value: Putative regulatory subunit of serine/threonine-protein phosphatase 4

value: Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complex PPP4C-PPP4R4

description: HEAT

description: HEAT

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Polar residues

database: DOI

value: Thoroughbred

value: Chromosome 24

value: Leucine-rich Repeat Variant

value: PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4

value: SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4


value: Aspartyl-tRNA synthetase 2, mitochondrial

value: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily

description: Aminoacyl-transfer RNA synthetases class-II family profile

database: AlphaFoldDB

value: Chromosome 5

value: F:aminoacyl-tRNA ligase activity

value: F:nucleic acid binding

value: P:tRNA aminoacylation for protein translation

value: Aspartate--tRNA ligase, mitochondrial

value: Bira Bifunctional Protein, Domain 2

value: GAD-like domain

value: Nucleic acid-binding proteins

database: HAMAP


value: Serine/threonine-protein

database: Rhea

database: ChEBI

value: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

description: Protein kinase

description: Disordered

description: Proton acceptor

value: P:regulation of early endosome to late endosome transport

value: P:regulation of stress-activated MAPK cascade

value: Dual specificity mitogen-activated protein kinase kinase 1

value: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN

value: MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2


value: Olfactomedin like 2A

value: Secreted

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Olfactomedin-like

description: Disordered

description: Disordered

description: Low complexity

description: Basic and acidic residues

description: Basic and acidic residues

description: Low complexity

value: Thoroughbred

database: Ensembl

database: GeneTree

database: Proteomes

value: Chromosome 25

value: C:extracellular region

database: InterPro

value: OLFACTOMEDIN-LIKE PROTEIN 2A

value: OLFACTOMEDIN-RELATED

value: OLF

database: SMART

database: PROSITE


value: Dual oxidase 1

value: Cell membrane

value: Membrane

value: Multi-pass membrane protein

value: Belongs to the peroxidase family

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: FAD-binding FR-type

value: Haem peroxidase domain superfamily, animal type

value: Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module

value: Ferredoxin reductase-like, C-terminal NADP-linked domain


value: Krev interaction trapped protein 1

value: Cell junction

value: Peripheral membrane protein

value: Cytoplasm, cytoskeleton

description: ANK

description: FERM

value: Chromosome 4

value: baseline

database: GO

value: C:anchoring junction

value: C:plasma membrane

value: P:negative regulation of developmental process

value: P:regulation of multicellular organismal development

value: krev interaction trapped protein 1 isoform X1

value: KRIT, N-terminal Nudix domain, NPxY motif-rich region

value: Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1

value: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)


value: Dynein light chain Tctex-type 2B

value: Belongs to the dynein light chain Tctex-type family

description: Disordered

description: Basic and acidic residues

value: Thoroughbred

value: Chromosome 19

database: ExpressionAtlas

value: tctex1 domain-containing protein 2

database: PANTHER

value: DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B

value: T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN

database: Pfam


value: C-X-C chemokine receptor type 3

value: Interferon-inducible protein 10 receptor

value: Receptor for the C-X-C chemokines CXCL9, CXCL10 and CXCL11, and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. Probably promotes cell chemotaxis response. Receptor for chemokine CCL21. Upon activation by PF4, induces activated T-lymphocyte migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling

value: Homomer. Forms heteromers with ACKR4. Interacts with PF4/CXCL4

value: Cell membrane

value: Multi-pass membrane protein

value: Belongs to the G protein-coupled receptor 1 family

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: G-protein coupled receptors family 1 profile

description: Disordered

description: Polar residues

value: Rhodopsin 7-helix transmembrane proteins

value: Family A G protein-coupled receptor-like


value: Myotubularin-related protein 9

value: Inactive phosphatidylinositol 3-phosphatase 9

value: Cell projection, ruffle membrane

value: Peripheral membrane protein

value: Cytoplasmic side

value: Cytoplasm, perinuclear region

value: Endoplasmic reticulum

value: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily

description: Myotubularin phosphatase

value: Chromosome 2

value: baseline

value: C:endoplasmic reticulum

value: C:perinuclear region of cytoplasm

value: C:ruffle membrane

database: CDD

database: FunFam

value: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

value: (Phosphotyrosine protein) phosphatases II


value: Palmitoyltransferase

name: L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA

value: Golgi apparatus membrane

value: Multi-pass membrane protein

value: The DHHC domain is required for palmitoyltransferase activity

commentType: DOMAIN

value: Belongs to the DHHC palmitoyltransferase family

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Palmitoyltransferase DHHC

description: Disordered

description: S-palmitoyl cysteine intermediate

database: PubMed

database: DOI

value: Thoroughbred

value: P:protein localization to plasma membrane

value: ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN


value: Protein-tyrosine-phosphatase

name: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate

value: Cytoplasmic vesicle, secretory vesicle membrane

value: Single-pass type I membrane protein

value: Synapse

description: Protein-tyrosine-phosphatase

description: Helical

description: Tyrosine-protein phosphatase

description: Tyrosine specific protein phosphatases

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Polar residues

description: Low complexity

description: Phosphocysteine intermediate

value: receptor-type tyrosine-protein phosphatase-like N isoform X2

value: Protein tyrosine phosphatase superfamily

value: Protein-tyrosine phosphatase receptor IA-2 ectodomain

value: IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C

value: RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE N2


value: Ubiquitin carboxyl-terminal hydrolase

name: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

value: Forms a ternary complex with RNF128 and OTUB1. Interacts (via C-terminal UCH catalytic domain) with OTUB1 isoform 1. Interacts with STAM2 (via SH3 domain). Interacts with DNAJB3, EGFR, EPS15, RASGRF1, RNF41, YWHAE, YWHAG and YWHAZ. Interacts with NBR1, RASGRF1, RNF41 and IST1. Associates with the ESCRT-0 complex and with microtubules. Interacts with BIRC6/bruce and KIF23/MKLP1

value: Cell membrane

value: Peripheral membrane protein

value: Cytoplasm

value: Endosome membrane

value: Nucleus

value: Belongs to the peptidase C19 family

description: Rhodanese

description: USP

description: Disordered

description: Disordered

description: Disordered

description: Basic and acidic residues

description: Basic and acidic residues

description: Basic and acidic residues

description: Basic and acidic residues

description: Basic and acidic residues

description: Polar residues

description: Nucleophile

description: Proton acceptor

value: Putative ubiquitin carboxyl-terminal hydrolase 8

value: Phosphotransferase system, lactose/cellobiose-type IIA subunit

value: Rhodanese/Cell cycle control phosphatase


value: DNA methyltransferase 3 like

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: PHD-type

value: Thoroughbred

database: AlphaFoldDB

database: OrthoDB

value: Chromosome 26

value: C:condensed nuclear chromosome

value: C:ESC/E(Z) complex

value: F:enzyme activator activity

value: F:enzyme binding

value: P:genomic imprinting

value: P:male meiosis I

value: P:negative regulation of DNA methylation-dependent heterochromatin formation

value: P:negative regulation of DNA-templated transcription

value: P:stem cell differentiation

value: P:transposable element silencing by piRNA-mediated DNA methylation

value: Zinc/RING finger domain, C3HC4 (zinc finger)

value: DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED


value: Myosin light chain 10

description: EF-hand

description: EF-hand

description: Disordered

description: Basic residues

description: Basic and acidic residues

database: RefSeq

database: GeneID

database: CTD

value: Chromosome 13

value: F:calcium ion binding

value: Myosin regulatory light chain 2, atrial isoform

value: Putative myosin regulatory light chain sqh

value: EF-hand


value: DNA (cytosine-5-)-methyltransferase

name: L-cysteinyl-[protein] + S-adenosyl-L-methionine = S-methyl-L-cysteinyl-[protein] + S-adenosyl-L-homocysteine + H(+)

database: Rhea

database: ChEBI

name: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+)

value: Nucleus

value: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: PWWP

description: PHD-type

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Basic and acidic residues

description: Basic residues

description: Polar residues

description: Low complexity

description: Basic and acidic residues

description: Polar residues

description: Basic and acidic residues

value: F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

value: F:RNA polymerase II-specific DNA-binding transcription factor binding

value: P:negative regulation of gene expression via chromosomal CpG island methylation

value: P:negative regulation of transcription by RNA polymerase II

value: DNA (Cytosine-5)-methyltransferase 3A isoform X1

value: DNA (Cytosine-5)-methyltransferase 3B isoform 3


value: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Branched chain amino acid catabolism plays a role in adipocyte differentiation by providing lipogenic acetyl-CoA pools in differentiated adipocytes. Mechanistically, acetyl-CoA derived from branched chain amino acid catabolism is used by EP300/p300 to acetylate and inhibit PRDM16, thereby preventing adipose tissue browning. May also function as a transporter of branched chain alpha-keto acids

name: L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate

name: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate

name: L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate

value: Homodimer

value: Mitochondrion

value: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family

description: Disordered

description: Gly residues

description: Low complexity

value: Thoroughbred

database: Ensembl

value: P:branched-chain amino acid catabolic process

value: D-amino Acid Aminotransferase, subunit A, domain 2

value: D-aminoacid aminotransferase-like PLP-dependent enzymes


source: PIRNR

value: Glycerol-3-phosphate acyltransferase 1, mitochondrial

value: GPAM

value: Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids. Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid. Has a narrow hydrophobic binding cleft that selects for a linear acyl chain. Catalytic activity is higher for substrates with a 16-carbon acyl chain

name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA

name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA

name: dodecanoyl-CoA + sn-glycerol 3-phosphate = 1-dodecanoyl-sn-glycerol 3-phosphate + CoA

name: sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA

name: sn-glycerol 3-phosphate + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphate + CoA

name: sn-glycerol 3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-sn-glycero-3-phosphate + CoA

name: sn-glycerol 3-phosphate + octadecanoyl-CoA = 1-octadecanoyl-sn-glycero-3-phosphate + CoA

value: Lipid metabolism

value: Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3

value: Mitochondrion outer membrane

value: Peripheral membrane protein

value: Belongs to the GPAT/DAPAT family

description: Phospholipid/glycerol acyltransferase

source: SMART

description: Disordered

value: GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1, MITOCHONDRIAL


scientificName: Paramecium tetraurelia

lineage: Eukaryota Sar Alveolata Ciliophora Intramacronucleata Oligohymenophorea Peniculida Parameciidae Paramecium

value: Serine/threonine-protein

name: L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)

name: L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

description: Protein kinase

description: Proton acceptor

authors:
Aury J.-M.
Jaillon O.
Duret L.
Noel B.
Jubin C.
Porcel B.M.
Segurens B.
Daubin V.
Anthouard V.
Aiach N.
Arnaiz O.
Billaut A.
Beisson J.
Blanc I.
Bouhouche K.
Camara F.
Duharcourt S.
Guigo R.
Gogendeau D.
Katinka M.
Keller A.-M.
Kissmehl R.
Klotz C.
Koll F.
Le Moue A.
Lepere C.
Malinsky S.
Nowacki M.
Nowak J.K.
Plattner H.
Poulain J.
Ruiz F.
Serrano V.
Zagulski M.
Dessen P.
Betermier M.
Weissenbach J.
Scarpelli C.
Schachter V.
Sperling L.
Meyer E.
Cohen J.
Wincker P.

title: Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia.

value: Stock d4-2

database: EMBL

database: KEGG

database: eggNOG

key: ToxonomicScope

value: Eukaryota

database: HOGENOM

database: InParanoid

database: OMA

database: Proteomes

value: Unassembled WGS sequence

value: F:protein serine/threonine kinase activity

value: OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED

value: PROTEIN KINASE DOMAIN-CONTAINING PROTEIN