entryType: UniProtKB unreviewed (TrEMBL)

description: Disordered

source: SAM

modifier: EXACT

type: Region

description: Disordered

description: Basic and acidic residues

type: Compositional bias

description: Polar residues

source: EMBL

Methyltransferase

category: Molecular function

source: ARBA

Reference proteome

category: Technical term

source: Proteomes

lineage: Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora

scientificName: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)

value: DUF890 domain-containing protein

proteinExistence: 4: Predicted

authors:
Galagan J.E.
Calvo S.E.
Borkovich K.A.
Selker E.U.
Read N.D.
Jaffe D.
FitzHugh W.
Ma L.J.
Smirnov S.
Purcell S.
Rehman B.
Elkins T.
Engels R.
Wang S.
Nielsen C.B.
Butler J.
Endrizzi M.
Qui D.
Ianakiev P.
Bell-Pedersen D.
Nelson M.A.
Werner-Washburne M.
Selitrennikoff C.P.
Kinsey J.A.
Braun E.L.
Zelter A.
Schulte U.
Kothe G.O.
Jedd G.
Mewes W.
Staben C.
Marcotte E.
Greenberg D.
Roy A.
Foley K.
Naylor J.
Stange-Thomann N.
Barrett R.
Gnerre S.
Kamal M.
Kamvysselis M.
Mauceli E.
Bielke C.
Rudd S.
Frishman D.
Krystofova S.
Rasmussen C.
Metzenberg R.L.
Perkins D.D.
Kroken S.
Cogoni C.
Macino G.
Catcheside D.
Li W.
Pratt R.J.
Osmani S.A.
DeSouza C.P.
Glass L.
Orbach M.J.
Berglund J.A.
Voelker R.
Yarden O.
Plamann M.
Seiler S.
Dunlap J.
Radford A.
Aramayo R.
Natvig D.O.
Alex L.A.
Mannhaupt G.
Ebbole D.J.
Freitag M.
Paulsen I.
Sachs M.S.
Lander E.S.
Nusbaum C.
Birren B.

database: PubMed

database: DOI

citationType: journal article

journal: Nature

title: The genome sequence of the filamentous fungus Neurospora crassa.

type: STRAIN

referencePositions: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

database: EMBL

key: ProteinId

key: Status

key: MoleculeType

database: RefSeq

key: NucleotideSequenceId

database: AlphaFoldDB

key: Description

database: SMR

database: STRING

database: PaxDb

database: GeneID

database: KEGG

database: VEuPathDB

database: HOGENOM

database: InParanoid

database: OMA

key: Fingerprint

database: OrthoDB

database: Proteomes

key: Component

value: Chromosome 4, Linkage Group IV

database: GO

key: GoTerm

value: F:23S rRNA (adenine(1618)-N(6))-methyltransferase activity

key: GoEvidenceType

value: P:rRNA base methylation

database: CDD

key: EntryName

key: MatchStatus

database: FunFam

value: DUF890 domain protein (AFU_orthologue AFUA_7G05590)

value: Vaccinia Virus protein VP39

database: InterPro

database: PANTHER

value: SAM-DEPENDENT METHYLTRANSFERASE

database: Pfam

database: SUPFAM


commentType: PATHWAY

value: Protein modification; protein ubiquitination

commentType: CAUTION

source: PROSITE-ProRule

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Helical

type: Transmembrane

description: RING-type

source: PROSITE

type: Domain

description: TRIAD supradomain

type: Active site

Membrane

category: Cellular component

Metal-binding

category: Ligand

Repeat

category: Domain

Ubl conjugation pathway

category: Biological process

value: RING-type domain-containing protein

database: PubMed

database: DOI

database: EMBL

database: RefSeq

database: AlphaFoldDB

value: FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED

value: UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED


commentType: SUBCELLULAR LOCATION

value: Membrane

value: Multi-pass membrane protein

commentType: SIMILARITY

source: RuleBase

value: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Major facilitator superfamily (MFS) profile

description: Disordered

description: Polar residues

value: Hexose transporter HXT13

proteinExistence: 3: Inferred from homology

value: MFS general substrate transporter like domains


description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Cytochrome b561

description: Disordered

value: Cytochrome b561 domain-containing protein

database: SMR

database: PaxDb

database: GeneID

database: KEGG

database: VEuPathDB

database: HOGENOM

value: Chromosome 6, Linkage Group II

value: CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN


description: Small EDRK-rich factor-like N-terminal

source: Pfam

description: Disordered

description: Basic and acidic residues

value: 4F5 family protein

database: FunCoup

key: Number of interactors

database: STRING

database: InParanoid

database: OrthoDB

database: Proteomes


value: Belongs to the RBT5 family

type: Signal

type: Chain

description: CFEM

description: Disordered

description: axial binding residue

database: ChEBI

type: Binding site

Disulfide bond

category: PTM

value: Anchored cell wall protein 5

database: OMA

value: Chromosome 2, Linkage Group V

database: GO

value: C:extracellular region

database: InterPro

database: Pfam

value: CFEM

database: SMART


value: Nucleus

description: Disordered

description: Disordered

description: Disordered

description: Low complexity

description: Basic and acidic residues

description: Basic residues

description: Basic and acidic residues

description: Basic and acidic residues

description: Acidic residues

source: Google

value: DNA-directed RNA polymerase III RPC4

database: PubMed

database: DOI

database: EMBL

database: RefSeq

database: AlphaFoldDB

value: C:RNA polymerase III complex

value: F:DNA binding

value: P:tRNA transcription by RNA polymerase III

value: DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4


value: Endomembrane system

value: Multi-pass membrane protein

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: CWH43-like N-terminal

description: Disordered

description: Low complexity

value: FK506 suppressor Sfk1

database: PaxDb

database: GeneID

database: KEGG

database: VEuPathDB

value: C:endomembrane system

value: FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED


value: Protein modification; protein sumoylation

value: Belongs to the ubiquitin-conjugating enzyme family

description: UBC core

description: Glycyl thioester intermediate

value: Ubiquitin carrier protein 9

value: Ubiquitin-conjugating enzyme E2-18 kDa

value: SUMO-conjugating enzyme UBC9

database: SMR

database: FunCoup

database: STRING

database: HOGENOM

database: InParanoid

database: OrthoDB

value: C:SUMO ligase complex

value: F:ATP binding


description: Helical

description: Helical

value: Uncharacterized protein

database: Proteomes

value: Chromosome 6, Linkage Group II

value: Magnesium transport protein CorA, transmembrane region


value: Membrane

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: SPX

description: Disordered

description: Polar residues

description: Basic residues

value: SPX domain-containing protein

value: F:phosphate transmembrane transporter activity

value: LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91


value: Single-pass type I membrane protein

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: L-type lectin-like domain-containing protein

description: Helical

description: L-type lectin-like

description: Disordered

type: Coiled coil

value: Chromosome 3, Linkage Group III

database: GO

value: C:COPII-coated ER to Golgi transport vesicle

value: C:endoplasmic reticulum membrane

value: C:endoplasmic reticulum-Golgi intermediate compartment

value: P:endoplasmic reticulum to Golgi vesicle-mediated transport

value: Similar to lectin family integral membrane protein


description: HIT

description: Disordered

description: Histidine triad motif

source: PIRSR

type: Motif

description: Pro residues

description: Tele-AMP-histidine intermediate

value: HIT domain-containing protein

database: PubMed

database: OMA

value: Chromosome 4, Linkage Group IV

value: F:catalytic activity

value: P:nucleotide metabolic process

value: HIT-like

database: InterPro

database: PANTHER

value: HIT DOMAIN-CONTAINING PROTEIN

value: HIT FAMILY PROTEIN 1

database: Pfam

value: HIT


value: Membrane

value: Belongs to the FUN14 family

description: Helical

description: Helical

description: Disordered

value: Uncharacterized protein

database: DOI

database: EMBL

database: RefSeq

database: AlphaFoldDB

database: PaxDb

value: C:mitochondrial outer membrane

value: P:autophagy of mitochondrion

value: FUN14 DOMAIN CONTAINING


commentType: CATALYTIC ACTIVITY

name: L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)

database: Rhea

database: ChEBI

directionType: left-to-right

name: L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)

value: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

description: Protein kinase

description: Disordered

description: Polar residues

description: Low complexity

description: Pro residues

description: Low complexity

description: Low complexity

description: Polar residues

description: Proton acceptor

value: P:positive regulation of calcium-mediated signaling

value: P:regulation of fungal-type cell wall organization

value: DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN

value: MITOGEN-ACTIVATED PROTEIN KINASE KINAE MKK2


commentType: FUNCTION

value: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism

name: beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate

name: beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate

commentType: COFACTOR

commentType: DOMAIN

value: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine

value: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily

description: Damage-control phosphatase ARMT1-like metal-binding

value: Sugar phosphate phosphatase

database: SMR

database: FunCoup

database: STRING

database: GeneID

database: KEGG

database: VEuPathDB

database: HOGENOM

value: Chromosome 2, Linkage Group V

value: F:fructose 6-phosphate aldolase activity

value: F:fructose-1-phosphatase activity

value: Uncharacterised protein PF01937, DUF89, domain 3


value: Uncharacterized protein

database: PubMed

database: InParanoid

database: OMA

database: OrthoDB

database: Proteomes


value: Antibiotic biosynthesis

value: Belongs to the cytochrome P450 family

description: Helical

description: axial binding residue

value: Cytochrome P450

database: DOI

database: EMBL

database: RefSeq

value: Chromosome 5, Linkage Group VI

database: GO

value: F:heme binding

value: F:iron ion binding

value: F:monooxygenase activity

value: F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen


value: Plays a role in pre-mRNA splicing

value: Nucleus

value: Belongs to the snRNP Sm proteins family

description: Sm

value: Small nuclear ribonucleoprotein G

value: snRNP-G

database: AlphaFoldDB

database: PaxDb

value: Chromosome 1, Linkage Group I

value: C:catalytic step 2 spliceosome

value: C:post-mRNA release spliceosomal complex

value: C:precatalytic spliceosome

value: C:SMN-Sm protein complex


value: Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1

value: Belongs to the FGGY kinase family

description: Carbohydrate kinase FGGY N-terminal

description: Carbohydrate kinase FGGY C-terminal

value: ATP:glycerol 3-phosphotransferase

value: glycerol kinase

database: SMR

database: FunCoup

database: UniPathway

key: RectionId

value: F:glycerol kinase activity

value: P:glycerol catabolic process

value: P:triglyceride metabolic process

database: CDD


source: PIRNR

value: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration

value: Endomembrane system

value: Belongs to the adaptor complexes large subunit family

description: Clathrin/coatomer adaptor adaptin-like N-terminal

description: Disordered

description: Low complexity

value: AP complex subunit beta

database: STRING

database: GeneID

database: KEGG

database: VEuPathDB

value: Chromosome 7, Linkage Group VII

value: C:AP-1 adaptor complex

value: F:clathrin binding

value: P:intracellular protein transport

database: FunFam

value: Leucine-rich Repeat Variant

value: ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER


value: Belongs to the eukaryotic ribosomal protein eL39 family

description: Disordered

description: Basic residues

source: PDB

value: 60S ribosomal protein L39

value: Large ribosomal subunit protein eL39

proteinExistence: 1: Evidence at protein level

database: PubMed

authors:
Shen L.
Su Z.
Yang K.
Wu C.
Becker T.
Bell-Pedersen D.
Zhang J.
Sachs M.S.

journal: Proc. Natl. Acad. Sci. U.S.A.

title: Structure of the translating Neurospora ribosome arrested by cycloheximide.

referencePositions: STRUCTURE BY ELECTRON MICROSCOPY (2.70 ANGSTROMS)

database: PDB

key: Method

value: EM

key: Resolution

key: Chains

database: EMDB

database: HOGENOM

database: InParanoid

database: OMA

database: OrthoDB

value: Chromosome 3, Linkage Group III

value: C:cytosolic large ribosomal subunit

value: F:structural constituent of ribosome

value: P:cytoplasmic translation

value: 60S ribosomal protein-like L39


description: BAR

description: Disordered

description: Low complexity

description: Low complexity

value: BAR adaptor protein RVS167

database: DOI

database: EMBL

database: RefSeq

database: AlphaFoldDB

database: PaxDb

database: Proteomes

value: Chromosome 2, Linkage Group V

database: GO

value: C:actin cortical patch

value: C:actin cytoskeleton

value: C:mating projection tip

value: C:medial cortex

value: C:Rvs161p-Rvs167p complex

value: Arfaptin homology (AH) domain/BAR domain

value: REDUCED VIABILITY UPON STARVATION PROTEIN 167


description: Disordered

value: Uncharacterized protein

database: GeneID

database: KEGG

value: Chromosome 4, Linkage Group IV


value: Membrane

value: Multi-pass membrane protein

value: Belongs to the SAT4 family

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Rhodopsin

description: Disordered

description: Basic and acidic residues

description: Polar residues

description: Basic and acidic residues

description: Gly residues

value: Rhodopsin domain-containing protein

database: VEuPathDB

value: PTH11-LIKE INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G11245)


description: Helical

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Gly residues

description: Low complexity

description: Polar residues

description: Low complexity

description: Gly residues

description: Low complexity

description: Low complexity

database: PubMed

database: STRING

value: Chromosome 7, Linkage Group VII

value: P:regulation of cell wall organization or biogenesis

value: EXTRACELLULAR MEMBRANE PROTEIN CFEM DOMAIN-CONTAINING PROTEIN


description: Endonuclease/exonuclease/phosphatase

value: Endonuclease/exonuclease/phosphatase

database: SMR

value: Chromosome 5, Linkage Group VI

value: F:catalytic activity

database: CDD

database: InterPro

value: Endo/exonuclease/phosphatase

database: PANTHER

value: ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)

value: ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09210)

database: Pfam


description: Heterokaryon incompatibility

value: Heterokaryon incompatibility domain-containing protein

database: DOI

database: HOGENOM

database: InParanoid

database: OMA

database: OrthoDB

value: HET

value: ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED

value: HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)


description: F-box

value: F-box domain-containing protein

database: EMBL

database: RefSeq

database: AlphaFoldDB

database: PaxDb

database: Proteomes

value: F-box

database: SMART

value: FBOX

database: SUPFAM

value: F-box domain

database: PROSITE


description: Rab-GAP TBC

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Low complexity

description: Low complexity

description: Polar residues

description: Low complexity

value: GAP for YPT7

value: GTPase-activating protein GYP7

database: PubMed

database: SMR

database: FunCoup

database: STRING

database: GeneID

database: KEGG

database: VEuPathDB

value: Chromosome 2, Linkage Group V

database: GO

value: F:GTPase activator activity

database: FunFam

value: GTPase activating protein (Gyp7)

value: putative rabgap domain of human tbc1 domain family member 14 like domains

value: SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED

value: TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN


description: G-patch

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Low complexity

description: Pro residues

description: Acidic residues

description: Gly residues

value: G-patch DNA repair protein

database: DOI

database: EMBL

database: HOGENOM

database: InParanoid

database: OrthoDB

value: F:nucleic acid binding

value: P:mRNA cis splicing, via spliceosome

value: P:mRNA splicing, via spliceosome

value: Putative G-patch DNA repair protein (Drt111)


value: Nucleus

description: Homeobox

description: Homeobox

type: DNA binding

description: Disordered

description: Polar residues

description: Low complexity

description: Polar residues

value: Homeobox domain-containing protein

database: RefSeq

database: AlphaFoldDB

database: PaxDb

database: OMA

database: Proteomes

value: F:DNA-binding transcription factor activity, RNA polymerase II-specific

value: F:RNA polymerase II cis-regulatory region sequence-specific DNA binding

value: P:cell differentiation

value: P:regulation of transcription by RNA polymerase II

value: HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX


value: HAD superfamily hydrolase

database: PubMed

database: SMR

database: FunCoup

value: Chromosome 4, Linkage Group IV

value: F:5'-nucleotidase activity

value: F:pseudouridine 5'-phosphatase activity

value: HAD superfamily hydrolase, putative

value: Haloacid dehalogenase-like hydrolase domain

value: HAD superfamily/HAD-like

value: Putative phosphatase, domain 2

database: InterPro

database: NCBIfam

database: PANTHER

database: Pfam

value: Hydrolase

database: SUPFAM

value: HAD-like


description: Helical

description: Disordered

description: Disordered

description: Polar residues

description: Polar residues

description: Basic and acidic residues

value: Uncharacterized protein

database: DOI

database: EMBL

database: STRING

database: GeneID

database: KEGG

database: VEuPathDB


value: Belongs to the FMO family

database: RefSeq

database: AlphaFoldDB

database: PaxDb

database: HOGENOM

database: InParanoid

database: OrthoDB

database: GO

value: F:flavin adenine dinucleotide binding

value: F:NADP binding

database: FunFam

value: Flavin-binding monooxygenase-like protein (AFU_orthologue AFUA_6G01900)

value: FAD/NAD(P)-binding domain

value: FMO-like

value: DIMETHYLANILINE MONOOXYGENASE


value: Nucleus, nucleolus

value: Belongs to the RPF2 family

description: Brix

description: Disordered

description: Basic residues

value: Ribosome biogenesis protein RPF2 homolog

value: Ribosome production factor 2 homolog

database: PubMed

database: SMR

database: FunCoup

database: OMA

database: Proteomes

value: Chromosome 1, Linkage Group I

value: F:rRNA binding

value: P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

value: P:ribosomal large subunit assembly

database: InterPro

value: Brix

database: PANTHER

value: BRIX DOMAIN CONTAINING PROTEIN

value: RIBOSOME PRODUCTION FACTOR 2 HOMOLOG


database: Rhea

name: [phosphate](n) + ATP = [phosphate](n+1) + ADP

database: ChEBI

value: Vacuole membrane

value: Multi-pass membrane protein

value: Belongs to the VTC4 family

description: Helical

description: Helical

description: Helical

description: SPX

description: Disordered

description: Acidic residues

description: Polar residues

description: Polar residues

value: Polyphosphate kinase

value: SPX-dependent polyphosphate polymerase VTC subunit 4

value: Vacuolar membrane polyphosphate polymerase catalytic subunit

value: Vacuolar transporter chaperone complex subunit 4

database: DOI

database: EMBL

value: C:vacuolar transporter chaperone complex

value: VACUOLAR TRANSPORTER CHAPERONE 1-RELATED

value: VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED


description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Helical

description: Disordered

description: Disordered

description: Low complexity

description: Low complexity

value: Capsule protein

database: RefSeq

database: AlphaFoldDB

database: STRING

database: PaxDb

database: GeneID

database: KEGG

database: VEuPathDB

value: KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED


value: Belongs to the RRN3 family

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Acidic residues

description: Acidic residues

value: RNA polymerase I-specific transcription initiation factor rrn3

database: PubMed

database: SMR

database: HOGENOM

database: InParanoid

database: OrthoDB

value: Chromosome 1, Linkage Group I

database: GO

value: F:RNA polymerase I core binding

value: F:RNA polymerase I general transcription initiation factor activity

value: P:transcription initiation at RNA polymerase I promoter

value: RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED

value: TRANSCRIPTION INITIATION FACTOR IA RRN3

database: Pfam


value: Lacks conserved residue(s) required for the propagation of feature annotation

description: PNPLA

description: Disordered

description: Basic and acidic residues

description: Polar residues

value: PNPLA domain-containing protein

database: OMA

database: Proteomes

value: P:arachidonate metabolic process

value: P:glycerolipid metabolic process

database: CDD

value: Cytosolic phospholipase A2 catalytic domain

value: Tetratricopeptide repeat domain

database: InterPro

database: PANTHER


description: F-BAR

description: Rho-GAP

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Polar residues

description: Low complexity

description: Low complexity

description: Pro residues

value: Rho GTPase activator

database: DOI

database: EMBL

database: RefSeq

database: AlphaFoldDB

database: FunCoup

database: STRING

value: C:cell cortex

value: C:cell division site

value: P:small GTPase-mediated signal transduction

value: Arfaptin homology (AH) domain/BAR domain


value: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes

commentType: SUBUNIT

value: Heterotrimer

value: Nucleus

value: Belongs to the NFYA/HAP2 subunit family

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Subunit association domain (SAD)

description: Polar residues

description: Polar residues

description: Polar residues

description: Pro residues

description: Basic and acidic residues

description: Polar residues

value: Transcriptional activator HAP2

database: PubMed

value: F:DNA-binding transcription factor activity, RNA polymerase II-specific

value: P:regulation of transcription by RNA polymerase II


ATP + H2O = ADP + phosphate + H(+)

database: Rhea

database: ChEBI

value: Belongs to the MCM family

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: MCM C-terminal AAA(+) ATPase

description: Disordered

description: Disordered

description: Disordered

description: Walker A

description: Walker B

description: Basic residues

description: Polar residues

description: Polar residues

description: Low complexity

description: Polar residues

description: Polar residues

description: Basic and acidic residues

value: F:single-stranded 3'-5' DNA helicase activity

value: P:DNA strand elongation involved in DNA replication

value: P:double-strand break repair via break-induced replication

value: P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication

value: mini-chromosome maintenance (MCM) complex, chain A, domain 1

value: P-loop containing nucleotide triphosphate hydrolases

value: DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER

value: P-loop containing nucleoside triphosphate hydrolases


description: N-acetyltransferase

database: SMR

database: PaxDb

database: GeneID

database: KEGG

database: VEuPathDB

database: InParanoid

database: OrthoDB

value: Chromosome 7, Linkage Group VII

value: F:acyltransferase activity, transferring groups other than amino-acyl groups

database: SUPFAM

value: Acyl-CoA N-acyltransferases (Nat)

database: PROSITE

value: GNAT


description: PH

description: Disordered

description: Disordered

description: Disordered

description: Low complexity

description: Polar residues

description: Low complexity

value: PH domain-containing protein, variant

database: DOI

database: EMBL

database: Proteomes

database: CDD

value: Arfaptin homology (AH) domain/BAR domain

value: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

database: InterPro

database: PANTHER

value: CYTOSKELETAL SIGNALING PROTEIN SLM1

value: PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1-RELATED

database: Pfam

database: SMART

value: PH


value: Membrane

value: Single-pass membrane protein

value: Belongs to the YSP2 family

description: VASt

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Basic residues

description: Low complexity

description: Basic and acidic residues

description: Low complexity

description: Polar residues

description: Basic and acidic residues

description: Polar residues

description: Low complexity

description: Polar residues

description: Polar residues

description: Basic and acidic residues

description: Low complexity

description: Acidic residues

description: Basic residues

value: C:endoplasmic reticulum-plasma membrane contact site


description: Disordered

description: Disordered

description: Low complexity

description: Low complexity

value: 37S ribosomal protein rsm22

database: PubMed

database: RefSeq

database: AlphaFoldDB

database: STRING

value: Chromosome 1, Linkage Group I

database: GO

value: C:RAVE complex

value: LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1

value: PROTEIN ROGDI HOMOLOG


value: Belongs to the inositol phosphokinase (IPK) family

description: Disordered

description: Low complexity

value: Kinase

database: SMR

database: GeneID

database: VEuPathDB

database: HOGENOM

database: OMA

value: Chromosome 4, Linkage Group IV

value: F:kinase activity

value: P:inositol phosphate biosynthetic process

value: Inositol polyphosphate kinase

value: IPK

value: INOSITOL POLYPHOSPHATE KINASE

value: INOSITOL POLYPHOSPHATE MULTIKINASE

value: SAICAR synthase-like


description: GIT Spa2 homology (SHD)

source: SMART

description: GIT Spa2 homology (SHD)

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Disordered

description: Polar residues

description: Polar residues

description: Basic and acidic residues

description: Basic and acidic residues

description: Polar residues

description: Polar residues

value: Spa2-like protein

database: DOI

authoringGroup: The Broad Institute Genome Sequencing Platform

authors:
Galagan J.
Henn M.R.
Hood H.
Radford A.
Collins R.A.
Walker B.
Young S.K.
Zeng Q.
Gargeya S.
Fitzgerald M.
Haas B.
Abouelleil A.
Allen A.W.
Alvarado L.
Arachchi H.M.
Berlin A.
Chapman S.B.
Chen Z.
Gainer-Dewar J.
Gnerre S.
Goldberg J.
Griggs A.
Gujja S.
Hansen M.
Howarth C.
Imamovic A.
Ireland A.
Larimer J.B.
McCowan C.
Murphy C.
Pearson M.D.
Poon T.W.
Priest M.
Roberts A.
Saif S.
Shea T.D.
Sisk P.
Shea T.
Sykes S.
Zucker J.
Kodira C.
Bowman B.
Colot H.
Ebbole D.
Rasmussen C.
Baker C.
Kalkman E.
Chen C.-H.
Shi M.
Mathur R.
Lambreghts R.
Collopy P.
Mehra A.
Schweredtfeger C.
Hong C.
Belden W.
Glass N.L.
Borkovich K.
Dunlap J.
Lander E.
Wortman J.
Nusbaum C.
Sachs M.
Birren B.

citationType: submission

submissionDatabase: EMBL/GenBank/DDBJ databases

title: The Genome Sequence of Neurospora crassa strain OR74A.

authors:
Zheng P.
Nguyen T.A.
Wong J.Y.
Lee M.
Nguyen T.A.
Fan J.S.
Yang D.
Jedd G.

journal: Nat. Commun.

title: Spitzenkorper assembly mechanisms reveal conserved features of fungal and metazoan polarity scaffolds.


value: Nucleus

description: Disordered

description: Disordered

description: Polar residues

description: Basic and acidic residues

description: Low complexity

value: BZIP-type transcription factor

database: EMBL

database: PaxDb

database: KEGG

database: OrthoDB

database: Proteomes

value: C:RNA polymerase II transcription regulator complex

value: F:DNA-binding transcription activator activity, RNA polymerase II-specific

value: F:transcription cis-regulatory region binding

value: YAP1 redox domain. Chain B

value: AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED


database: Rhea

database: ChEBI

value: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

value: Lacks conserved residue(s) required for the propagation of feature annotation

description: Protein kinase

description: AGC-kinase C-terminal

description: Disordered

description: Disordered

description: Polar residues

description: Low complexity

description: Polar residues

description: Proton acceptor

description: Phosphothreonine

type: Modified residue

value: Serine/threonine-protein

value: F:protein serine/threonine kinase activity

value: Non-specific serine/threonine protein kinase

value: C2 domain (Calcium/lipid-binding domain, CaLB)