count: 35 rows: - file: genes/ARATH/FLC/FLC-ai-review.yaml gene: FLC evidence_type: IEA reference: GO_REF:0000002 original: GO:0045944 positive regulation of transcription by RNA polymerase II replacement: GO:0000122 negative regulation of transcription by RNA polymerase II flip: + -> - - file: genes/ARATH/SHR/SHR-ai-review.yaml gene: SHR evidence_type: IMP reference: PMID:20739610 original: GO:0045930 negative regulation of mitotic cell cycle replacement: GO:0045931 positive regulation of mitotic cell cycle flip: '- -> +' - file: genes/ARATH/SVP/SVP-ai-review.yaml gene: SVP evidence_type: IEA reference: GO_REF:0000002 original: GO:0045944 positive regulation of transcription by RNA polymerase II replacement: GO:0000122 negative regulation of transcription by RNA polymerase II flip: + -> - - file: genes/DROME/AMPKalpha/AMPKalpha-ai-review.yaml gene: AMPKalpha evidence_type: IMP reference: PMID:36899949 original: GO:0008284 positive regulation of cell population proliferation replacement: GO:0008285 negative regulation of cell population proliferation flip: + -> - - file: genes/DROME/AMPKalpha/AMPKalpha-ai-review.yaml gene: AMPKalpha evidence_type: IMP reference: PMID:36899949 original: GO:1904263 positive regulation of TORC1 signaling replacement: GO:1904262 negative regulation of TORC1 signaling flip: + -> - - file: genes/DROME/Lkb1/Lkb1-ai-review.yaml gene: Lkb1 evidence_type: IMP reference: PMID:36899949 original: GO:0008284 positive regulation of cell population proliferation replacement: GO:0008285 negative regulation of cell population proliferation flip: + -> - - file: genes/DROME/Lkb1/Lkb1-ai-review.yaml gene: Lkb1 evidence_type: IMP reference: PMID:36899949 original: GO:1904263 positive regulation of TORC1 signaling replacement: GO:1904262 negative regulation of TORC1 signaling flip: + -> - - file: genes/DROME/Mo25/Mo25-ai-review.yaml gene: Mo25 evidence_type: TAS reference: PMID:36899949 original: GO:1904263 positive regulation of TORC1 signaling replacement: GO:1904262 negative regulation of TORC1 signaling flip: + -> - - file: genes/DROME/Stlk/Stlk-ai-review.yaml gene: Stlk evidence_type: TAS reference: PMID:36899949 original: GO:1904263 positive regulation of TORC1 signaling replacement: GO:1904262 negative regulation of TORC1 signaling flip: + -> - - file: genes/human/ABCC8/ABCC8-ai-review.yaml gene: ABCC8 evidence_type: IEA reference: GO_REF:0000107 original: GO:1905604 negative regulation of blood-brain barrier permeability replacement: GO:1905605 positive regulation of blood-brain barrier permeability flip: '- -> +' - file: genes/human/AGT/AGT-ai-review.yaml gene: AGT evidence_type: IGI reference: PMID:17416596 original: GO:1903598 positive regulation of gap junction assembly replacement: GO:1903597 negative regulation of gap junction assembly flip: + -> - - file: genes/human/ANLN/ANLN-ai-review.yaml gene: ANLN evidence_type: IMP reference: PMID:23870127 original: GO:1904172 positive regulation of bleb assembly replacement: GO:1904171 negative regulation of bleb assembly flip: + -> - - file: genes/human/ATP13A2/ATP13A2-ai-review.yaml gene: ATP13A2 evidence_type: TAS reference: PMID:22885599 original: GO:1905166 negative regulation of lysosomal protein catabolic process replacement: GO:1905167 positive regulation of lysosomal protein catabolic process flip: '- -> +' - file: genes/human/CBL/CBL-ai-review.yaml gene: CBL evidence_type: IMP reference: PMID:17003487 original: GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction replacement: GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction flip: + -> - - file: genes/human/CD47/CD47-ai-review.yaml gene: CD47 evidence_type: IBA reference: GO_REF:0000033 original: GO:0050766 positive regulation of phagocytosis replacement: GO:0050765 negative regulation of phagocytosis flip: + -> - - file: genes/human/CD47/CD47-ai-review.yaml gene: CD47 evidence_type: IEA reference: GO_REF:0000002 original: GO:0050766 positive regulation of phagocytosis replacement: GO:0050765 negative regulation of phagocytosis flip: + -> - - file: genes/human/CDKN1B/CDKN1B-ai-review.yaml gene: CDKN1B evidence_type: TAS reference: Reactome:R-HSA-69656 original: GO:0045740 positive regulation of DNA replication replacement: GO:0008156 negative regulation of DNA replication flip: + -> - - file: genes/human/CIB2/CIB2-ai-review.yaml gene: CIB2 evidence_type: IDA reference: PMID:23023331 original: GO:0007204 positive regulation of cytosolic calcium ion concentration replacement: GO:0051481 negative regulation of cytosolic calcium ion concentration flip: + -> - - file: genes/human/CIB2/CIB2-ai-review.yaml gene: CIB2 evidence_type: IDA reference: PMID:26173970 original: GO:0007204 positive regulation of cytosolic calcium ion concentration replacement: GO:0051481 negative regulation of cytosolic calcium ion concentration flip: + -> - - file: genes/human/CLYBL/CLYBL-ai-review.yaml gene: CLYBL evidence_type: IEA reference: GO_REF:0000107 original: GO:0106121 positive regulation of cobalamin catabolic process replacement: GO:0106122 negative regulation of cobalamin catabolic process flip: + -> - - file: genes/human/CLYBL/CLYBL-ai-review.yaml gene: CLYBL evidence_type: IDA reference: PMID:29056341 original: GO:0106121 positive regulation of cobalamin catabolic process replacement: GO:0106122 negative regulation of cobalamin catabolic process flip: + -> - - file: genes/human/FGFR4/FGFR4-ai-review.yaml gene: FGFR4 evidence_type: IMP reference: PMID:19085950 original: GO:0010628 positive regulation of gene expression replacement: GO:0010629 negative regulation of gene expression flip: + -> - - file: genes/human/GNAI2/GNAI2-ai-review.yaml gene: GNAI2 evidence_type: IEA reference: GO_REF:0000107 original: GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway replacement: GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway flip: + -> - - file: genes/human/HDAC6/HDAC6-ai-review.yaml gene: HDAC6 evidence_type: IDA reference: PMID:31857589 original: GO:1905336 negative regulation of aggrephagy replacement: GO:1905335 positive regulation of aggrephagy flip: '- -> +' - file: genes/human/LRP5/LRP5-ai-review.yaml gene: LRP5 evidence_type: IMP reference: PMID:17680723 original: GO:0045600 positive regulation of fat cell differentiation replacement: GO:0045599 negative regulation of fat cell differentiation flip: + -> - - file: genes/human/LRP5/LRP5-ai-review.yaml gene: LRP5 evidence_type: IMP reference: PMID:17680723 original: GO:0045668 negative regulation of osteoblast differentiation replacement: GO:0045669 positive regulation of osteoblast differentiation flip: '- -> +' - file: genes/human/MCL1/MCL1-ai-review.yaml gene: MCL1 evidence_type: IEA reference: GO_REF:0000107 original: GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway replacement: GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway flip: + -> - - file: genes/human/MCL1/MCL1-ai-review.yaml gene: MCL1 evidence_type: IGI reference: PMID:23858059 original: GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway replacement: GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway flip: + -> - - file: genes/human/NLRP3/NLRP3-ai-review.yaml gene: NLRP3 evidence_type: IMP reference: PMID:12483741 original: GO:0032691 negative regulation of interleukin-1 beta production replacement: GO:0032731 positive regulation of interleukin-1 beta production flip: '- -> +' - file: genes/human/NLRP3/NLRP3-ai-review.yaml gene: NLRP3 evidence_type: IMP reference: PMID:12483741 original: GO:0050728 negative regulation of inflammatory response replacement: GO:0050729 positive regulation of inflammatory response flip: '- -> +' - file: genes/human/NLRP3/NLRP3-ai-review.yaml gene: NLRP3 evidence_type: IMP reference: PMID:16531551 original: GO:0050728 negative regulation of inflammatory response replacement: GO:0050729 positive regulation of inflammatory response flip: '- -> +' - file: genes/human/NLRP3/NLRP3-ai-review.yaml gene: NLRP3 evidence_type: IMP reference: PMID:17178985 original: GO:0050728 negative regulation of inflammatory response replacement: GO:0050729 positive regulation of inflammatory response flip: '- -> +' - file: genes/human/PINK1/PINK1-ai-review.yaml gene: PINK1 evidence_type: IMP reference: PMID:19880420 original: GO:0090200 positive regulation of release of cytochrome c from mitochondria replacement: GO:0090201 negative regulation of release of cytochrome c from mitochondria flip: + -> - - file: genes/worm/ced-9/ced-9-ai-review.yaml gene: ced-9 evidence_type: EXP reference: PMID:10846174 original: GO:0043065 positive regulation of apoptotic process replacement: GO:0043066 negative regulation of apoptotic process flip: + -> - - file: genes/worm/daf-18/daf-18-ai-review.yaml gene: daf-18 evidence_type: NAS reference: PMID:20207731 original: GO:0046628 positive regulation of insulin receptor signaling pathway replacement: GO:0046627 negative regulation of insulin receptor signaling pathway flip: + -> -