# GENERATED FILE - do not edit by hand. # Source of truth: the sibling *.sssom.yaml # Regenerate: uv run python projects/TCDB/sssom_to_terms.py .sssom.yaml -o .terms.yaml # Validate: uv run linkml-term-validator validate-data .terms.yaml -s src/ai_gene_review/schema/tcdb_go_mapping.yaml -t TCDBGOMappingSet --labels -c conf/oak_config.yaml mappings: - subject: id: TC:1 label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015267 label: channel activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 1 is a whole class/subclass (level 1); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 235/500, not scored). Source: GO xref.' - subject: id: TC:1.A.11 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008519 label: ammonium channel activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 23/23 reviewed Swiss-Prot proteins carrying TC 1.A.11 (level 3) also carry GO:0008519 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.A.23.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008381 label: mechanosensitive monoatomic ion channel activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 1.A.23.2.1 (level 5) also carry GO:0008381 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.A.9 label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0160039 label: serotonin-gated chloride channel activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/59 reviewed Swiss-Prot proteins carrying TC 1.A.9 (level 3) also carry GO:0160039 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.B.1.-.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015288 label: porin activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 22/22 reviewed Swiss-Prot proteins carrying TC 1.B.1.-.- (level 3) also carry GO:0015288 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.B.11.-.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015473 label: fimbrial usher porin activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 13/14 reviewed Swiss-Prot proteins carrying TC 1.B.11.-.- (level 3) also carry GO:0015473 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.B.12.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015474 label: autotransporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 0/26 reviewed Swiss-Prot proteins carrying TC 1.B.12.-.- (level 3) also carry GO:0015474 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.B.9.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015483 label: long-chain fatty acid transporting porin activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 1.B.9.1.1 (level 5) also carry GO:0015483 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:1.C label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0140911 label: pore-forming activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 1.C is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 19/436, not scored). Source: GO xref.' - subject: id: TC:2.A label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015291 label: secondary active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 2.A is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 318/500, not scored). Source: GO xref.' - subject: id: TC:2.A.1.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0009679 label: hexose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 5/466 reviewed Swiss-Prot proteins carrying TC 2.A.1.-.- (level 3) also carry GO:0009679 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1 label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0005351 label: carbohydrate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 35/88 reviewed Swiss-Prot proteins carrying TC 2.A.1.1 (level 4) also carry GO:0005351 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015517 label: galactose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.1.1 (level 5) also carry GO:0015517 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1.10 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005364 label: maltose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.10 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005364 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.11 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005352 label: alpha-glucoside:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.1.11 (level 5) also carry GO:0005352 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1.12 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015304 label: D-glucose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.12 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015304 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.13 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015284 label: fructose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.13 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015284 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015518 label: arabinose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015518 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015519 label: D-xylose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.1.3 (level 5) also carry GO:0015519 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1.4 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015304 label: D-glucose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.4 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015304 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.5 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0008516 label: hexose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.5 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0008516 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015304 label: D-glucose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.6 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015304 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0050782 label: galactose uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.6 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0050782 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.8 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005366 label: myo-inositol:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.1.8 (level 5) also carry GO:0005366 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.1.9 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015517 label: galactose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.9 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015517 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.1.9 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015528 label: lactose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.1.9 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015528 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.10.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015506 label: nucleoside:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.10.1 (level 5) also carry GO:0015506 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.10.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015537 label: xanthosine:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.10.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015537 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.12.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015538 label: sialic acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.12.1 (level 5) also carry GO:0015538 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.14.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015296 label: monoatomic anion:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.14.- is a specific system (level 4) with 36 reviewed member(s), but 0 carry GO:0015296 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.14.10 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015306 label: sialate:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.14.10 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015306 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.14.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015539 label: hexuronate:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.14.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015539 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.14.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005436 label: sodium:phosphate symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.14.6 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005436 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.15.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015540 label: 3-hydroxyphenyl propionate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.15.2 (level 5) also carry GO:0015540 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.1 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015344 label: siderophore uptake transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.1 (level 5) also carry GO:0015344 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.2 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015345 label: ferric enterobactin:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.16.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015345 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.16.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.3 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015346 label: ferric triacetylfusarinine C:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.16.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015346 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.16.4 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.4 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.5 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.5 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.6 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.16.6 (level 5) also carry GO:0015343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.16.7 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.16.7 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015343 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.16.8 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.1.16.8 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.1.16.9 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015343 label: siderophore-iron transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.16.9 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015343 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.17.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015541 label: secondary active cyanate transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.17.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015541 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.11 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015311 label: monoamine:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.2.11 (level 5) also carry GO:0015311 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.2.12 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015311 label: monoamine:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.2.12 (level 5) also carry GO:0015311 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.2.13 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005278 label: acetylcholine:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.13 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005278 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.16 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015312 label: polyamine:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.16 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015312 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.17 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015313 label: fluconazole:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.17 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015313 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015309 label: cycloheximide:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015309 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.4 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015520 label: tetracycline:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.4 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015520 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.2.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015310 label: benomyl:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.2.6 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015310 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.25.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015325 label: acetyl-CoA:CoA antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.25.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015325 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.27.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015544 label: phenyl propionate uniporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.27.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015544 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.3.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015314 label: aminotriazole:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.3.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015314 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.4.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015315 label: organophosphate:phosphate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 8/9 reviewed Swiss-Prot proteins carrying TC 2.A.1.4.- (level 4) also carry GO:0015315 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.4.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015526 label: hexose-phosphate:phosphate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.4.1 (level 5) also carry GO:0015526 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.4.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015527 label: glycerol-phosphate:phosphate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.4.3 (level 5) also carry GO:0015527 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.5.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015528 label: lactose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.5.1 (level 5) also carry GO:0015528 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.5.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015529 label: raffinose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.5.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015529 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.5.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0008506 label: sucrose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.5.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0008506 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.50.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140211 label: folic acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.50.1 (level 5) also carry GO:0140211 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.6.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015531 label: citrate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.6.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015531 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.6.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015532 label: alpha-ketoglutarate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.6.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015532 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.6.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015533 label: shikimate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.6.6 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015533 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.1.7.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015535 label: fucose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.1.7.1 (level 5) also carry GO:0015535 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.1.9.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015317 label: phosphate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.1.9.- is a specific system (level 4) with 8 reviewed member(s), but 0 carry GO:0015317 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.10.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015649 label: 2-keto-3-deoxygluconate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.10.1.1 (level 5) also carry GO:0015649 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.14.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015650 label: lactate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.14.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015650 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.15.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015653 label: glycine betaine:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.15.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015653 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.16.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015366 label: malate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.16.2.1 (level 5) also carry GO:0015366 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.17.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015333 label: peptide:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 12/40 reviewed Swiss-Prot proteins carrying TC 2.A.17.-.- (level 3) also carry GO:0015333 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.18.5.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015495 label: gamma-aminobutyric acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.18.5.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015495 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.18.6.13 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140901 label: L-asparagine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.18.6.13 (level 5) also carry GO:0140901 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.18.6.13 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140902 label: L-glutamine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.18.6.13 (level 5) also carry GO:0140902 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.18.6.8 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140893 label: neutral amino acid, sodium:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.18.6.8 (level 5) also carry GO:0140893 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.19.-.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015368 label: calcium:monoatomic cation antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 26/30 reviewed Swiss-Prot proteins carrying TC 2.A.19.-.- (level 3) also carry GO:0015368 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.19.2.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015369 label: calcium:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 8/8 reviewed Swiss-Prot proteins carrying TC 2.A.19.2.- (level 4) also carry GO:0015369 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.19.4.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008273 label: calcium, potassium:sodium antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.19.4.1 (level 5) also carry GO:0008273 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.2.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0009669 label: sucrose:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 12/25 reviewed Swiss-Prot proteins carrying TC 2.A.2.-.- (level 3) also carry GO:0009669 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.2.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015486 label: glycoside-pentoside-hexuronide:cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 0/25 reviewed Swiss-Prot proteins carrying TC 2.A.2.-.- (level 3) also carry GO:0015486 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.2.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015487 label: melibiose:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.2.1.1 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.2.3.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015488 label: glucuronide:cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.2.3.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015488 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.2.4.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0009669 label: sucrose:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.2.4.1 (level 5) also carry GO:0009669 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.20.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0009673 label: low-affinity phosphate transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/14 reviewed Swiss-Prot proteins carrying TC 2.A.20.-.- (level 3) also carry GO:0009673 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.20.2.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005316 label: high-affinity phosphate:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.20.2.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005316 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.21.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015498 label: pantothenate:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.21.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015498 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.21.3.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0005362 label: low-affinity D-glucose:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 3/13 reviewed Swiss-Prot proteins carrying TC 2.A.21.3.- (level 4) also carry GO:0005362 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.3.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005412 label: D-glucose:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 8/13 reviewed Swiss-Prot proteins carrying TC 2.A.21.3.- (level 4) also carry GO:0005412 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.3.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015371 label: galactose:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/13 reviewed Swiss-Prot proteins carrying TC 2.A.21.3.- (level 4) also carry GO:0015371 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.4.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005367 label: myo-inositol:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.21.4.- is a specific system (level 4) with 2 reviewed member(s), but 0 carry GO:0005367 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.21.5.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015373 label: monoatomic anion:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/7 reviewed Swiss-Prot proteins carrying TC 2.A.21.5.- (level 4) also carry GO:0015373 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.5.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008507 label: sodium:iodide symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.21.5.1 (level 5) also carry GO:0008507 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.5.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008523 label: sodium-dependent multivitamin transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.21.5.2 (level 5) also carry GO:0008523 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.21.6.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015401 label: urea:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.21.6.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015401 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.22.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0005328 label: neurotransmitter:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 3/38 reviewed Swiss-Prot proteins carrying TC 2.A.22.-.- (level 3) also carry GO:0005328 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005335 label: serotonin:sodium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.1.1 (level 5) also carry GO:0005335 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.1.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005334 label: norepinephrine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.1.2 (level 5) also carry GO:0005334 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.1.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005330 label: dopamine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.1.3 (level 5) also carry GO:0005330 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005298 label: proline:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.2.1 (level 5) also carry GO:0005298 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.2.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015374 label: neutral, basic amino acid:sodium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.2.3 (level 5) also carry GO:0015374 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.3.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005332 label: gamma-aminobutyric acid:sodium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.3.2 (level 5) also carry GO:0005332 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.3.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005369 label: taurine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.3.3 (level 5) also carry GO:0005369 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.3.4 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005309 label: creatine:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.22.3.4 (level 5) also carry GO:0005309 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.22.3.5 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005307 label: choline:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.22.3.5 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005307 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.23.3.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005295 label: neutral L-amino acid:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.23.3.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005295 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.26.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015657 label: branched-chain amino acid:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.26.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015657 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.27.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015501 label: glutamate:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.27.1.1 (level 5) also carry GO:0015501 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.28.-.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0008508 label: bile acid:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 8/14 reviewed Swiss-Prot proteins carrying TC 2.A.28.-.- (level 3) also carry GO:0008508 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.28.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005343 label: organic acid:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.28.1.1 (level 5) also carry GO:0005343 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.29.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005471 label: ATP:ADP antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.29.1.1 (level 5) also carry GO:0005471 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.29.13.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005469 label: succinate:fumarate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.29.13.1 (level 5) also carry GO:0005469 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.29.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015367 label: oxoglutarate:malate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.29.2.1 (level 5) also carry GO:0015367 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.29.2.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015364 label: dicarboxylate:phosphate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.29.2.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015364 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.29.7.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015137 label: citrate transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.29.7.2 (level 5) also carry GO:0015137 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.3.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015492 label: phenylalanine:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.3.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015492 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.3.1.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015493 label: lysine:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.3.1.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015493 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.3.1.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015494 label: aromatic amino acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.3.1.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015494 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.3.1.4 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015495 label: gamma-aminobutyric acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.3.1.4 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015495 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.3.10.5 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0005314 label: high-affinity L-glutamate transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.3.10.5 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0005314 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.3.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015496 label: putrescine:ornithine antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.3.2.1 (level 5) also carry GO:0015496 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.3.2.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0043872 label: lysine:cadaverine antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.3.2.2 (level 5) also carry GO:0043872 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.3.4.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015495 label: gamma-aminobutyric acid:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.3.4.2 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.3.8.5 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015327 label: cystine:glutamate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 1/2 reviewed Swiss-Prot proteins carrying TC 2.A.3.8.5 (level 5) also carry GO:0015327 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.30 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015377 label: chloride:monoatomic cation symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 16/16 reviewed Swiss-Prot proteins carrying TC 2.A.30 (level 3) also carry GO:0015377 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.30.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008511 label: sodium:potassium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.30.1.1 (level 5) also carry GO:0008511 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.30.1.5 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015379 label: potassium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.30.1.5 (level 5) also carry GO:0015379 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.30.4.- label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015378 label: sodium:chloride symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.30.4.- (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.31.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140829 label: bicarbonate:monoatomic anion antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.31.1.1 (level 5) also carry GO:0140829 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.31.2.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008510 label: sodium:bicarbonate symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.31.2.1 (level 5) also carry GO:0008510 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.31.2.4 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140892 label: sodium,bicarbonate:chloride antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.31.2.4 (level 5) also carry GO:0140892 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.35.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015385 label: sodium:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.35.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015385 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.36.-.- label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015385 label: sodium:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 37/42 reviewed Swiss-Prot proteins carrying TC 2.A.36.-.- (level 3) also carry GO:0015385 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.37.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015386 label: potassium:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 7/28 reviewed Swiss-Prot proteins carrying TC 2.A.37.-.- (level 3) also carry GO:0015386 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.37.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015503 label: glutathione-regulated potassium exporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 1/2 reviewed Swiss-Prot proteins carrying TC 2.A.37.1.1 (level 5) also carry GO:0015503 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.37.1.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015503 label: glutathione-regulated potassium exporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 1/2 reviewed Swiss-Prot proteins carrying TC 2.A.37.1.2 (level 5) also carry GO:0015503 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.38.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0015387 label: potassium:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 0/19 reviewed Swiss-Prot proteins carrying TC 2.A.38.-.- (level 3) also carry GO:0015387 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.38.3.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0009674 label: potassium:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.38.3.1 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.39.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015504 label: cytosine:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.39.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015504 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.39.3.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005274 label: allantoin:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.39.3.1 (level 5) also carry GO:0005274 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.4.1.4 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015341 label: zinc efflux antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.4.1.4 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015341 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.4.2.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015341 label: zinc efflux antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.4.2.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015341 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.40.6.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0008520 label: L-ascorbate:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.40.6.1 (level 5) also carry GO:0008520 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.41.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015506 label: nucleoside:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.41.1.1 (level 5) also carry GO:0015506 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.41.2.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015390 label: purine-specific nucleoside:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.41.2.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015390 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.41.2.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015389 label: pyrimidine- and adenosine-specific:sodium symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.41.2.3 (level 5) also carry GO:0015389 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.44.4.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015360 label: acetate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.44.4.1 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.47.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015361 label: low-affinity sodium:dicarboxylate symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.47.1.1 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.47.1.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015382 label: sodium:sulfate symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.47.1.2 (level 5) also carry GO:0015382 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.47.1.4 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015362 label: high-affinity sodium:dicarboxylate symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.47.1.4 (level 5) also carry GO:0015362 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.47.3.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015515 label: citrate:succinate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.47.3.2 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015515 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.47.3.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015516 label: tartrate:succinate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.47.3.3 (level 5) also carry GO:0015516 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.48 label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0008518 label: folate:monoatomic anion antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/6 reviewed Swiss-Prot proteins carrying TC 2.A.48 (level 3) also carry GO:0008518 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.5.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0000006 label: high-affinity zinc transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.5.1.1 (level 5) also carry GO:0000006 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.53.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0008512 label: sulfate:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 0/38 reviewed Swiss-Prot proteins carrying TC 2.A.53.-.- (level 3) also carry GO:0008512 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.53.2.18 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140900 label: chloride:bicarbonate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.53.2.18 (level 5) also carry GO:0140900 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.53.2.2 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015383 label: sulfate:bicarbonate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.53.2.2 (level 5) also carry GO:0015383 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.66.1.20 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140968 label: polyspecific organic cation:proton antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 2.A.66.1.20 (level 5) also carry GO:0140968 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.66.2.12 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015161 label: lipid III floppase activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 2.A.66.2.12 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:2.A.66.2.3 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015161 label: lipid III floppase activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.66.2.3 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015161 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:2.A.7.-.- label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0009670 label: triose-phosphate:phosphate antiporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 0/160 reviewed Swiss-Prot proteins carrying TC 2.A.7.-.- (level 3) also carry GO:0009670 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:2.A.7.6 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015561 label: rhamnose:proton symporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 2.A.7.6 is a specific system (level 4) with 1 reviewed member(s), but 0 carry GO:0015561 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:3 label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015399 label: primary active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3 is a whole class/subclass (level 1); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 210/500, not scored). Source: GO xref.' - subject: id: TC:3.A.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0140359 label: ABC-type transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 254/500 reviewed Swiss-Prot proteins carrying TC 3.A.1 (level 3) also carry GO:0140359 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.1.1.11 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0033154 label: ABC-type oligogalacturonide transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 3.A.1.1.11 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:3.A.1.105.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:1901242 label: ABC-type doxorubicin transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 3.A.1.105.1 is a specific system (level 5) with 2 reviewed member(s), but 0 carry GO:1901242 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:3.A.1.115.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140679 label: ABC-type sodium transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 2/2 reviewed Swiss-Prot proteins carrying TC 3.A.1.115.1 (level 5) also carry GO:0140679 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.1.19.1 label: '' predicate: id: skos:narrowMatch label: narrow match object: id: GO:0048502 label: ABC-type thiamine transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NOT_JUSTIFIED_AT_LEVEL. Evidence: 1/3 reviewed Swiss-Prot proteins carrying TC 3.A.1.19.1 (level 5) also carry GO:0048502 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.1.202.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005260 label: intracellularly ATP-gated chloride channel activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 1/1 reviewed Swiss-Prot proteins carrying TC 3.A.1.202.1 (level 5) also carry GO:0005260 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.1.207.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015432 label: ABC-type bile acid transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: NO_REVIEWED_MEMBER. No reviewed Swiss-Prot protein carries a DR TCDB xref to 3.A.1.207.2 (TrEMBL-only, or the reviewed protein lacks the xref), so propagation cannot be assessed from reviewed evidence. Source: GO xref.' - subject: id: TC:3.A.1.209.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0015433 label: ABC-type peptide antigen transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 2/2 reviewed Swiss-Prot proteins carrying TC 3.A.1.209.1 (level 5) also carry GO:0015433 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.1.210.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0140481 label: ABC-type iron-sulfur cluster transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 3.A.1.210.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0140481 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:3.A.1.4.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015425 label: ATPase-coupled nonpolar-amino acid transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 3.A.1.4.1 is a specific system (level 5) with 6 reviewed member(s), but 0 carry GO:0015425 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:3.A.10 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0009678 label: diphosphate hydrolysis-driven proton transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 10/10 reviewed Swiss-Prot proteins carrying TC 3.A.10 (level 3) also carry GO:0009678 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.2.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0046933 label: proton-transporting ATP synthase activity, rotational mechanism mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 8/8 reviewed Swiss-Prot proteins carrying TC 3.A.2.1.1 (level 5) also carry GO:0046933 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.2.1.2 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0046932 label: sodium-transporting ATP synthase activity, rotational mechanism mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 3.A.2.1.2 is a specific system (level 5) with 8 reviewed member(s), but 0 carry GO:0046932 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:3.A.3 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0140358 label: P-type transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 84/109 reviewed Swiss-Prot proteins carrying TC 3.A.3 (level 3) also carry GO:0140358 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.3.1.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0005391 label: P-type sodium:potassium-exchanging transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 4/5 reviewed Swiss-Prot proteins carrying TC 3.A.3.1.1 (level 5) also carry GO:0005391 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.A.4.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015446 label: ATPase-coupled arsenite transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: UNCERTAIN. Evidence: 1/2 reviewed Swiss-Prot proteins carrying TC 3.A.4.1.1 (level 5) also carry GO:0015446 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.B label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015451 label: decarboxylation-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.B is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 15/20, not scored). Source: GO xref.' - subject: id: TC:3.B.-.-.- label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015451 label: decarboxylation-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.B.-.-.- is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 15/20, not scored). Source: GO xref.' - subject: id: TC:3.C label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015452 label: methyl transfer-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.C is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 0/8, not scored). Source: GO xref.' - subject: id: TC:3.C.-.-.- label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015452 label: methyl transfer-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.C.-.-.- is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 0/8, not scored). Source: GO xref.' - subject: id: TC:3.D label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015453 label: oxidoreduction-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.D is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 181/410, not scored). Source: GO xref.' - subject: id: TC:3.D.-.-.- label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015453 label: oxidoreduction-driven active transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.D.-.-.- is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 181/410, not scored). Source: GO xref.' - subject: id: TC:3.D.4.5.1 label: '' predicate: id: skos:exactMatch label: exact match object: id: GO:0009486 label: cytochrome bo3 ubiquinol oxidase activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: JUSTIFIED. Evidence: 4/4 reviewed Swiss-Prot proteins carrying TC 3.D.4.5.1 (level 5) also carry GO:0009486 (GO closure). Source: GO xref + UniProt member evidence.' - subject: id: TC:3.E label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0015454 label: light-driven active monoatomic ion transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 3.E is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 1/65, not scored). Source: GO xref.' - subject: id: TC:4.A label: '' predicate: id: skos:broadMatch label: broad match object: id: GO:0008982 label: protein-N(PI)-phosphohistidine-carbohydrate phosphotransferase activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: CLASS_LEVEL. TC 4.A is a whole class/subclass (level 2); the GO term is broad by construction and out of scope for substrate-level propagation (evidence 66/94, not scored). Source: GO xref.' - subject: id: TC:9.A.11.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015089 label: high-affinity copper ion transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 9.A.11.1.1 is a specific system (level 5) with 6 reviewed member(s), but 0 carry GO:0015089 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:9.A.9.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0015090 label: low-affinity ferric iron ion transmembrane transporter activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 9.A.9.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0015090 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.' - subject: id: TC:9.B.133.1.1 label: '' predicate: id: skos:relatedMatch label: related match object: id: GO:0019833 label: ice nucleation activity mapping_justification: semapv:CompositeMatching comment: 'Propagation: GAP_CANDIDATE. 9.B.133.1.1 is a specific system (level 5) with 1 reviewed member(s), but 0 carry GO:0019833 (closure) -- a reverse-gap lead (the member is under-annotated), not a propagation basis. Source: GO xref + UniProt.'