# Generated by trace_graft_paths.py from the live PANTHER tree API and QuickGO.
cases:
  - case: "purM"
    gene: "PSEPK/purM"
    family: "PTHR10520"
    family_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
    term: "GO:0004637 phosphoribosylamine-glycine ligase activity"
    family_leaves: 170
    grafts:
      - graft: "PTN002237315"
        graft_node:
          persistent_id: "PTN002237315"
          sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          gene_symbol: "purM"
          organism: "Pseudomonas aeruginosa"
          definition: "Phosphoribosylformylglycinamidine cyclo-ligase"
        ibd: "PTN000055158"
        steps_from_ibd: 5
        path_ibd_to_graft:
          - persistent_id: "PTN000055158"
            event_type: "SPECIATION"
            taxonomic_range: "LUCA"
            species: "LUCA"
            sf_id: "PTHR10520:SF12"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          - persistent_id: "PTN000741919"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          - persistent_id: "PTN007444794"
            event_type: "HORIZ_TRANSFER"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          - persistent_id: "PTN001315038"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          - persistent_id: "PTN001315040"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
          - persistent_id: "PTN002237315"
            sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
            gene_symbol: "purM"
            organism: "Pseudomonas aeruginosa"
            definition: "Phosphoribosylformylglycinamidine cyclo-ligase"
    ibd_nodes:
      - persistent_id: "PTN000055158"
        event_type: "SPECIATION"
        taxonomic_range: "LUCA"
        species: "LUCA"
        sf_id: "PTHR10520:SF12"
        sf_name: "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3"
        leaves: 170
        seeds:
          - "FB:FBgn0000053"
          - "MGI:MGI:95654"
          - "PomBase:SPBC405.01"
          - "RGD:1308717"
        clades:
          - child: "PTN000055159"
            event_type: "SPECIATION"
            taxonomic_range: "Archaea-Eukaryota"
            leaves: 79
            subfamilies:
              - "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 (72)"
              - "PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (7)"
            top_definitions:
              - "phosphoribosylformylglycinamidine cyclo-ligase (72)"
              - "Phosphoribosylformylglycinamidine cyclo-ligase (6)"
              - "Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic (1)"
            contains_graft: false
          - child: "PTN000741919"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            leaves: 91
            subfamilies:
              - "TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 (89)"
              - "PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE (2)"
            top_definitions:
              - "Trifunctional purine biosynthetic protein adenosine-3 (34)"
              - "Phosphoribosylformylglycinamidine cyclo-ligase (32)"
              - "ATP-grasp domain-containing protein (6)"
              - "phosphoribosylformylglycinamidine cyclo-ligase (4)"
            contains_graft: true
  - case: "moeB"
    gene: "PSEPK/moeB"
    family: "PTHR10953"
    family_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
    term: "GO:0004792 thiosulfate-cyanide sulfurtransferase activity"
    family_leaves: 1090
    grafts:
      - graft: "PTN002250299"
        graft_node:
          persistent_id: "PTN002250299"
          sf_name: "MOLYBDOPTERIN-SYNTHASE ADENYLYLTRANSFERASE"
          gene_symbol: "moeB"
          organism: "Pseudomonas aeruginosa"
          definition: "Molybdopterin biosynthesis MoeB protein"
        ibd: "PTN000102040"
        steps_from_ibd: 6
        path_ibd_to_graft:
          - persistent_id: "PTN000102040"
            event_type: "SPECIATION"
            taxonomic_range: "LUCA"
            species: "LUCA"
            sf_id: "PTHR10953:SF102"
            sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
          - persistent_id: "PTN008957377"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
          - persistent_id: "PTN000102608"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
          - persistent_id: "PTN000102622"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
          - persistent_id: "PTN002589895"
            event_type: "DUPLICATION"
            taxonomic_range: "Gammaproteobacteria"
            sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
          - persistent_id: "PTN000860087"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_id: "PTHR10953:SF194"
            sf_name: "MOLYBDOPTERIN-SYNTHASE ADENYLYLTRANSFERASE"
          - persistent_id: "PTN002250299"
            sf_name: "MOLYBDOPTERIN-SYNTHASE ADENYLYLTRANSFERASE"
            gene_symbol: "moeB"
            organism: "Pseudomonas aeruginosa"
            definition: "Molybdopterin biosynthesis MoeB protein"
    ibd_nodes:
      - persistent_id: "PTN000102040"
        event_type: "SPECIATION"
        taxonomic_range: "LUCA"
        species: "LUCA"
        sf_id: "PTHR10953:SF102"
        sf_name: "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"
        leaves: 1090
        seeds:
          - "SGD:S000001153"
        clades:
          - child: "PTN000102041"
            event_type: "SPECIATION"
            taxonomic_range: "Archaea-Eukaryota"
            leaves: 1049
            subfamilies:
              - "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 (130)"
              - "SUMO-ACTIVATING ENZYME SUBUNIT 2 (118)"
              - "NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT (114)"
              - "UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 (112)"
            top_definitions:
              - "E1 ubiquitin-activating enzyme (145)"
              - "NEDD8-activating enzyme E1 catalytic subunit (108)"
              - "Ubiquitin-like modifier-activating enzyme ATG7 (89)"
              - "Ubiquitin-like modifier-activating enzyme 5 (86)"
            contains_graft: false
          - child: "PTN008957377"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            leaves: 41
            subfamilies:
              - "ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 (27)"
              - "MOLYBDOPTERIN-SYNTHASE ADENYLYLTRANSFERASE (7)"
              - "SULFUR CARRIER PROTEIN THIS ADENYLYLTRANSFERASE (5)"
              - "SLL6053 PROTEIN (2)"
            top_definitions:
              - "Molybdopterin biosynthesis MoeB protein (7)"
              - "Molybdopterin biosynthesis protein (4)"
              - "Molybdopterin-synthase adenylyltransferase (4)"
              - "Molybdopterin biosynthesis protein MoeB (3)"
            contains_graft: true
  - case: "moaA"
    gene: "PSEPK/moaA"
    family: "PTHR22960"
    family_name: ""
    term: "GO:0061799 cyclic pyranopterin monophosphate synthase activity"
    family_leaves: 144
    grafts:
      - graft: "PTN002344120"
        graft_node:
          persistent_id: "PTN002344120"
          sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          gene_symbol: "moaA1"
          organism: "Pseudomonas aeruginosa"
          definition: "GTP 3',8-cyclase 1"
        ibd: "PTN000539172"
        steps_from_ibd: 6
        path_ibd_to_graft:
          - persistent_id: "PTN000539172"
            event_type: "SPECIATION"
            taxonomic_range: "LUCA"
            species: "LUCA"
            sf_id: "PTHR22960:SF0"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN008586331"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN007722652"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN002344071"
            event_type: "DUPLICATION"
            taxonomic_range: "Gammaproteobacteria"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN002743202"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN002344118"
            event_type: "DUPLICATION"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
          - persistent_id: "PTN002344120"
            sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
            gene_symbol: "moaA1"
            organism: "Pseudomonas aeruginosa"
            definition: "GTP 3',8-cyclase 1"
    ibd_nodes:
      - persistent_id: "PTN000539172"
        event_type: "SPECIATION"
        taxonomic_range: "LUCA"
        species: "LUCA"
        sf_id: "PTHR22960:SF0"
        sf_name: "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1"
        leaves: 141
        seeds:
          - "MGI:MGI:1928904"
          - "UniProtKB:Q9NZB8"
        clades:
          - child: "PTN008586302"
            event_type: "SPECIATION"
            taxonomic_range: "Archaea-Eukaryota"
            leaves: 112
            subfamilies:
              - "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 (110)"
              - "GTP 3',8-CYCLASE (2)"
            top_definitions:
              - "GTP 3',8-cyclase (57)"
              - "Radical SAM core domain-containing protein (11)"
              - "Molybdenum cofactor synthesis 1 (11)"
              - "Probable GTP 3',8-cyclase (7)"
            contains_graft: false
          - child: "PTN008586331"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            leaves: 29
            subfamilies:
              - "MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 (23)"
              - "GTP 3',8-CYCLASE (6)"
            top_definitions:
              - "GTP 3',8-cyclase (25)"
              - "GTP 3',8-cyclase 1 (2)"
              - "GTP 3',8-cyclase 2 (2)"
            contains_graft: true
  - case: "fliI_sctN"
    gene: "CAUVC,HELPJ,PSEPK/fliI; SHIFL,YEREN/sctN"
    family: "PTHR15184"
    family_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
    term: "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism"
    family_leaves: 332
    grafts:
      - graft: "PTN000390110"
        graft_node:
          persistent_id: "PTN000390110"
          sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          gene_symbol: "fliI"
          organism: "Bradyrhizobium diazoefficiens"
          definition: "Flagellum-specific ATP synthase"
        ibd: "PTN008558586"
        steps_from_ibd: 5
        path_ibd_to_graft:
          - persistent_id: "PTN008558586"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
          - persistent_id: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR15184:SF9"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390105"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN004469768"
            event_type: "HORIZ_TRANSFER"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN002309652"
            event_type: "DUPLICATION"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390110"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
            gene_symbol: "fliI"
            organism: "Bradyrhizobium diazoefficiens"
            definition: "Flagellum-specific ATP synthase"
      - graft: "PTN002689426"
        graft_node:
          persistent_id: "PTN002689426"
          sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          gene_symbol: "fliI"
          organism: "Helicobacter pylori"
          definition: "Flagellum-specific ATP synthase"
        ibd: "PTN008558586"
        steps_from_ibd: 3
        path_ibd_to_graft:
          - persistent_id: "PTN008558586"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
          - persistent_id: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR15184:SF9"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390105"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN002689426"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
            gene_symbol: "fliI"
            organism: "Helicobacter pylori"
            definition: "Flagellum-specific ATP synthase"
      - graft: "PTN002309653"
        graft_node:
          persistent_id: "PTN002309653"
          sf_name: "FLAGELLUM-SPECIFIC ATP SYNTHASE"
          gene_symbol: "fliI"
          organism: "Pseudomonas aeruginosa"
          definition: "Flagellum-specific ATP synthase"
        ibd: "PTN008558586"
        steps_from_ibd: 5
        path_ibd_to_graft:
          - persistent_id: "PTN008558586"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
          - persistent_id: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR15184:SF9"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390105"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001032656"
            event_type: "DUPLICATION"
            taxonomic_range: "Gammaproteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390111"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_id: "PTHR15184:SF81"
            sf_name: "FLAGELLUM-SPECIFIC ATP SYNTHASE"
          - persistent_id: "PTN002309653"
            sf_name: "FLAGELLUM-SPECIFIC ATP SYNTHASE"
            gene_symbol: "fliI"
            organism: "Pseudomonas aeruginosa"
            definition: "Flagellum-specific ATP synthase"
      - graft: "PTN001807734"
        graft_node:
          persistent_id: "PTN001807734"
          sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          gene_symbol: "sctN1"
          organism: "Salmonella typhimurium"
          definition: "SPI-1 type 3 secretion system ATPase"
        ibd: "PTN008558586"
        steps_from_ibd: 7
        path_ibd_to_graft:
          - persistent_id: "PTN008558586"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
          - persistent_id: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR15184:SF9"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390105"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001032656"
            event_type: "DUPLICATION"
            taxonomic_range: "Gammaproteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807729"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN007644296"
            event_type: "DUPLICATION"
            taxonomic_range: "Enterobacteriaceae"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807731"
            event_type: "SPECIATION"
            taxonomic_range: "Enterobacteriaceae"
            species: "Enterobacteriaceae"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807734"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
            gene_symbol: "sctN1"
            organism: "Salmonella typhimurium"
            definition: "SPI-1 type 3 secretion system ATPase"
      - graft: "PTN001807733"
        graft_node:
          persistent_id: "PTN001807733"
          sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          gene_symbol: "sctN"
          organism: "Yersinia pestis"
          definition: "Type 3 secretion system ATPase"
        ibd: "PTN008558586"
        steps_from_ibd: 7
        path_ibd_to_graft:
          - persistent_id: "PTN008558586"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
          - persistent_id: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR15184:SF9"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN000390105"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001032656"
            event_type: "DUPLICATION"
            taxonomic_range: "Gammaproteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807729"
            event_type: "SPECIATION"
            taxonomic_range: "Gammaproteobacteria"
            species: "Gammaproteobacteria"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN007644296"
            event_type: "DUPLICATION"
            taxonomic_range: "Enterobacteriaceae"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807731"
            event_type: "SPECIATION"
            taxonomic_range: "Enterobacteriaceae"
            species: "Enterobacteriaceae"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
          - persistent_id: "PTN001807733"
            sf_name: "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE"
            gene_symbol: "sctN"
            organism: "Yersinia pestis"
            definition: "Type 3 secretion system ATPase"
    ibd_nodes:
      - persistent_id: "PTN008558586"
        event_type: "DUPLICATION"
        taxonomic_range: "Eubacteria"
        sf_name: "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"
        leaves: 330
        seeds:
          - "PomBase:SPAC222.12c"
          - "SGD:S000003882"
          - "UniProtKB:P06576"
          - "UniProtKB:P0ABB4"
        clades:
          - child: "PTN000390097"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            leaves: 31
            subfamilies:
              - "SPI-1 TYPE 3 SECRETION SYSTEM ATPASE (21)"
              - "FLAGELLUM-SPECIFIC ATP SYNTHASE (8)"
              - "SPI-2 TYPE 3 SECRETION SYSTEM ATPASE (2)"
            top_definitions:
              - "Flagellum-specific ATP synthase (13)"
              - "Type 3 secretion system ATPase (4)"
              - "protein-secreting ATPase (2)"
              - "Flagellar protein export ATPase FliI (2)"
            contains_graft: true
          - child: "PTN008558588"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            leaves: 299
            subfamilies:
              - "ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL (224)"
              - "ATP SYNTHASE SUBUNIT BETA-1, MITOCHONDRIAL-RELATED (38)"
              - "ATP SYNTHASE SUBUNIT BETA, CHLOROPLASTIC (20)"
              - "ATP SYNTHASE SUBUNIT BETA (17)"
            top_definitions:
              - "ATP synthase subunit beta (206)"
              - "ATP synthase subunit beta, chloroplastic (31)"
              - "H(+)-transporting two-sector ATPase (25)"
              - "ATP synthase subunit beta, mitochondrial (17)"
            contains_graft: false
  - case: "dapE"
    gene: "PSEPK/dapE"
    family: "PTHR43808"
    family_name: ""
    term: "GO:0008777 acetylornithine deacetylase activity"
    family_leaves: 170
    grafts:
      - graft: "PTN002887524"
        graft_node:
          persistent_id: "PTN002887524"
          sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
          gene_symbol: "dapE"
          organism: "Neisseria meningitidis serogroup b"
          definition: "Succinyl-diaminopimelate desuccinylase"
        ibd: "PTN000865743"
        steps_from_ibd: 3
        path_ibd_to_graft:
          - persistent_id: "PTN000865743"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR43808:SF31"
            sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
          - persistent_id: "PTN005184321"
            event_type: "HORIZ_TRANSFER"
            sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
          - persistent_id: "PTN000110599"
            event_type: "SPECIATION"
            taxonomic_range: "Proteobacteria"
            species: "Proteobacteria"
            sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
          - persistent_id: "PTN002887524"
            sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
            gene_symbol: "dapE"
            organism: "Neisseria meningitidis serogroup b"
            definition: "Succinyl-diaminopimelate desuccinylase"
    ibd_nodes:
      - persistent_id: "PTN000865743"
        event_type: "SPECIATION"
        taxonomic_range: "Eubacteria"
        species: "Eubacteria"
        sf_id: "PTHR43808:SF31"
        sf_name: "N-ACETYL-L-CITRULLINE DEACETYLASE"
        leaves: 29
        seeds:
          - "UniProtKB:P23908"
          - "UniProtKB:Q8P8J5"
        clades:
          - child: "PTN008685562"
            event_type: "SPECIATION"
            taxonomic_range: "Terrabacteria"
            leaves: 9
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (9)"
            top_definitions:
              - "Xaa-His dipeptidase (1)"
              - "Putative dipeptidase YtjP (1)"
              - "Lmo1620 protein (1)"
              - "Putative dipeptidase SAOUHSC_01868 (1)"
            contains_graft: false
          - child: "PTN000110632"
            event_type: "LEAF"
            taxonomic_range: "Bacteroides thetaiotaomicron"
            leaves: 1
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (1)"
            top_definitions:
              - "Acetylornithine deacetylase (1)"
            contains_graft: false
          - child: "PTN000865752"
            event_type: "LEAF"
            taxonomic_range: "Rhodopirellula baltica"
            leaves: 1
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (1)"
            top_definitions:
              - "Acetylornithine deacetylase ArgE (1)"
            contains_graft: false
          - child: "PTN000110574"
            event_type: "LEAF"
            taxonomic_range: "Aquifex aeolicus"
            leaves: 1
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (1)"
            top_definitions:
              - "Succinyl-diaminopimelate desuccinylase (1)"
            contains_graft: false
          - child: "PTN000865753"
            event_type: "LEAF"
            taxonomic_range: "Fusobacterium nucleatum"
            leaves: 1
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (1)"
            top_definitions:
              - "Xaa-His dipeptidase (1)"
            contains_graft: false
          - child: "PTN005184321"
            event_type: "HORIZ_TRANSFER"
            taxonomic_range: ""
            leaves: 16
            subfamilies:
              - "N-ACETYL-L-CITRULLINE DEACETYLASE (11)"
              - "ACETYLORNITHINE DEACETYLASE (5)"
            top_definitions:
              - "Acetylornithine deacetylase (5)"
              - "Succinyl-diaminopimelate desuccinylase (2)"
              - "Uncharacterized protein YgeY (1)"
              - "Probable peptidic bond hydrolase (1)"
            contains_graft: true
  - case: "mdh"
    gene: "PSEPK/mdh"
    family: "PTHR43128"
    family_name: "L-LACTATE DEHYDROGENASE"
    term: "GO:0004459 L-lactate dehydrogenase (NAD+) activity"
    family_leaves: 271
    grafts:
      - graft: "PTN002454946"
        graft_node:
          persistent_id: "PTN002454946"
          event_type: "SPECIATION"
          taxonomic_range: "Archaea"
          species: "Archaea"
          sf_name: "L-LACTATE DEHYDROGENASE"
        ibd: null
    ibd_nodes: []
  - case: "eryAIII"
    gene: "SACEN/eryAIII"
    family: "PTHR43775"
    family_name: "SI:DKEY-61P9.11"
    term: "GO:0004312 fatty acid synthase activity"
    family_leaves: 200
    grafts:
      - graft: "PTN000918870"
        graft_node:
          persistent_id: "PTN000918870"
          event_type: "SPECIATION"
          taxonomic_range: "Actinomycetales"
          species: "Actinomycetales"
          sf_name: "INACTIVE PHENOLPHTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE TYPE I PKS1-RELATED"
        ibd: "PTN000196555"
        steps_from_ibd: 3
        path_ibd_to_graft:
          - persistent_id: "PTN000196555"
            event_type: "SPECIATION"
            taxonomic_range: "LUCA"
            species: "LUCA"
            sf_id: "PTHR43775:SF37"
            sf_name: "SI:DKEY-61P9.11"
          - persistent_id: "PTN002886638"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            sf_name: "SI:DKEY-61P9.11"
          - persistent_id: "PTN008452887"
            event_type: "SPECIATION"
            taxonomic_range: "Eubacteria"
            species: "Eubacteria"
            sf_id: "PTHR43775:SF51"
            sf_name: "INACTIVE PHENOLPHTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE TYPE I PKS1-RELATED"
          - persistent_id: "PTN000918870"
            event_type: "SPECIATION"
            taxonomic_range: "Actinomycetales"
            species: "Actinomycetales"
            sf_name: "INACTIVE PHENOLPHTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE TYPE I PKS1-RELATED"
    ibd_nodes:
      - persistent_id: "PTN000196555"
        event_type: "SPECIATION"
        taxonomic_range: "LUCA"
        species: "LUCA"
        sf_id: "PTHR43775:SF37"
        sf_name: "SI:DKEY-61P9.11"
        leaves: 200
        seeds:
          - "FB:FBgn0042627"
          - "FB:FBgn0283427"
          - "MGI:MGI:95485"
          - "RGD:620665"
          - "UniProtKB:P49327"
          - "dictyBase:DDB_G0275077"
        clades:
          - child: "PTN000196556"
            event_type: "SPECIATION"
            taxonomic_range: "Eukaryota"
            leaves: 164
            subfamilies:
              - "FATTY ACID SYNTHASE (37)"
              - "SI:DKEY-61P9.11 (35)"
              - "ASPERFURANONE POLYKETIDE SYNTHASE AFOG-RELATED (15)"
              - "SYNTHASE, PUTATIVE (JCVI)-RELATED (13)"
            top_definitions:
              - "Uncharacterized protein (34)"
              - "Fatty acid synthase (26)"
              - "Ketosynthase family 3 (KS3) domain-containing protein (11)"
              - "Polyketide synthase, putative (JCVI) (6)"
            contains_graft: false
          - child: "PTN002886638"
            event_type: "DUPLICATION"
            taxonomic_range: "Eubacteria"
            leaves: 36
            subfamilies:
              - "SI:DKEY-61P9.11 (23)"
              - "INACTIVE PHENOLPHTHIOCEROL SYNTHESIS POLYKETIDE SYNTHASE TYPE I PKS1-RELATED (13)"
            top_definitions:
              - "Polyketide synthase (4)"
              - "Type I polyketide synthase (3)"
              - "3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (2)"
              - "Irp1 protein (1)"
            contains_graft: true