module: dmel_augmin_complex
title: Augmin (HAUS) complex in Drosophila melanogaster
label: Augmin complex
module_type: PROTEIN_COMPLEX
description: >-
  Augmin is an eight-subunit complex that recruits the gamma-tubulin ring
  complex to the sides of existing microtubules, so that new microtubules
  branch from old ones. This microtubule-dependent nucleation amplifies
  microtubule number within the mitotic and meiotic spindle. In Drosophila the
  complex was first identified in S2 cells, where loss of augmin subunits
  reduces spindle microtubule density.
summary: >-
  Eight-subunit complex that tethers the gamma-tubulin ring complex to
  existing spindle microtubules for branching nucleation.
concepts:
  - {id: GO:0070652, label: HAUS complex}
cellular_components:
  - {id: GO:0005819, label: spindle}
group: AUG
function_note: >-
  No molecular function is assigned: augmin is a structural adaptor that
  attaches the gamma-tubulin ring complex to the side of existing
  microtubules, and its subunits carry only microtubule binding and
  protein-macromolecule adaptor terms in GOA.