# PN dossier: SERP1

- review_batch: proteostasis-batch-2026-06-11
- review_yaml: genes/human/SERP1/SERP1-ai-review.yaml
- PN workbook rows: 1

## PN row 1: ER proteostasis | Protein transport | SEC61 channel accessory protein
- UniProt: Q9Y6X1
- In branches: ER
- PN-node mapping records (path + ancestors):
    - [group] ER proteostasis|Protein transport|SEC61 channel accessory protein
        status=no_mapping scope= GO=[]
        rationale: Reviewed as a broad PN category rather than a single GO class. The member genes span multiple activities, complexes, or contexts, so direct propagation from this node would overstate the shared biology.
    - [class] ER proteostasis|Protein transport
        status=mapped scope=ok_for_propagation_to_go GO=[GO:0015031 protein transport]
        rationale: The PN ER Protein transport class groups ER-targeting and ER-insertion pathways. GO protein transport is the appropriate propagation target, while the source class remains ER-specific and broader than any single GO transport subtype.
    - [branch] ER proteostasis
        status=no_mapping scope= GO=[]
        rationale: Reviewed as a top-level PN branch. This is a systems/taxonomy umbrella, not a direct GO assertion; narrower child curations carry any propagating GO mappings.

## Projected GO annotations (1)
- GO:0015031 protein transport | scope=ok_for_propagation_to_go | goa_status=new_to_goa | from=ER proteostasis|Protein transport