## DNAJC9
- **UniProt:** Q8WXX5 · **batch:** proteostasis-batch-2026-06-07b · **review status:** COMPLETE
- **PN placement:** `Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone` ; **PN-node mapping:** type=mapped, scope=ok_for_propagation_to_go, GO:0030544 Hsp70 protein binding (group/class/branch = no_mapping)
- **Consistency:** Strong. Notes, review YAML, and PN all agree DNAJC9 is a J-domain HSP70 co-chaperone (binds HSPA1A/1B/8 via J domain, stimulates HSP70 ATPase). No contradictions. The review additionally develops the dual histone-H3-H4 chaperone role (MCM2 complex; PMID:33857403) that the single PN row does not capture, but this is enrichment, not conflict.
- **PN story / NEW pressure:** PN asserts only Hsp70-binding, which is captured: GOA/review already carry GO:0031072 (heat shock protein binding, parent of GO:0030544) plus GO:0032781, GO:0051087, GO:0101031. The projected GO:0030544 (verified real, child of GO:0031072) is a defensible refinement (`goa_status=more_specific_than_existing_goa` is accurate — GOA has the parent GO:0031072). No NEW term needed; the histone-chaperone axis (GO:0042393, GO:0006334) is the gene's distinctive biology and is already fully annotated in the review.
- **Mapping strategy:** This gene does not require changing the node. GO:0030544 is appropriately narrower than the review's broad coverage and is defensible for the J-domain-cochaperone type. The PN row legitimately under-describes DNAJC9 (ignores histone role), but that is by-design for a type-level mapping.
- **Evidence alignment:** PN row carries no reference titles; review anchors on PMID:17182002 (HSP70 co-chaperone, verified) and PMID:33857403 (histone chaperone, verified). No divergence — review evidence is a superset.
- **Verdict:** Consistent; PN GO:0030544 already captured (as parent in GOA) and defensible. No edits required.