## SEC62
- **UniProt:** Q99442 · **batch:** proteostasis-batch-2026-06-11 · **review status:** COMPLETE
- **PN placement:** `ER proteostasis|Protein transport|SEC61 channel complex component`; also `ALP|Autophagy substrate selection|Selective autophagy receptor|ERphagy` and `ALP|Microautophagy|Microreticulophagy`; **PN-node mapping:** group mapped, ok_for_propagation_to_go, GO:0005784 (Sec61 translocon complex); class GO:0015031 (protein transport); ERphagy type mapped GO:0061709 (reticulophagy); microreticulophagy = context_only/too_broad.
- **Consistency:** Strong agreement. Deep research, notes, and review YAML all describe SEC62 as a Sec61-translocon-associated targeting receptor for small presecretory proteins (post-translational import) plus a recovery-phase ER-phagy receptor (GABARAP/LC3). PN's three rows (translocon component, ERphagy receptor, microreticulophagy) map cleanly onto the review's translocation core + non-core reticulophagy. No contradictions.
- **PN story / NEW pressure:** PN's two roles are already in GOA/review. Translocon: review has GO:0031204, GO:0006620, GO:0008320, GO:0015031. ERphagy: review keeps GO:0061709 (KEEP_AS_NON_CORE). The one PN-projected term absent from GOA is GO:0005784 Sec61 translocon complex (verified real; definition explicitly admits translocon-associated/TRAP proteins, so SEC62 qualifies). Defensible ADD as a CC. Conclude: ADD GO:0005784 (translocon-associated, not channel-core); ERphagy/transport already captured.
- **Mapping strategy:** Mapping is sound. GO:0005784 is appropriately specific (the dossier's `more_specific_than_existing_goa` is correct — GOA has only ER membrane/rough ER/ER). GO:0015031 protein transport is a defensibly broad class-level target (not over-reaching like the TOMM20/HSPA8 precedent, since it's flagged generic). Microreticulophagy correctly held context_only. No mapping change needed.
- **Evidence alignment:** Excellent overlap. PN row 2 titles ("Translocon component Sec62 acts in ER turnover during stress recovery"; "Selective Autophagy: ATG8...LIR...Cargo Receptors") match the review's reticulophagy framing (review cites PMID:31006538). Translocon evidence (PMID:22375059, 29719251, 32133789) is review-only but congruent. No divergence.
- **Verdict:** CONSISTENT. One actionable gap: add Sec61 translocon complex CC.
- **Recommended edits:** [YAML] Add GO:0005784 Sec61 translocon complex (part_of/located_in, translocon-associated) to SEC62 existing_annotations/core_functions, matching the PN-projected term and the verified GO definition (TRAP-inclusive).