## SRP19
- **UniProt:** P09132 · **batch:** proteostasis-batch-2026-06-11 · **review status:** COMPLETE
- **PN placement:** `ER proteostasis|Protein transport|Signal recognition particle component` ; **PN-node mapping:** group=mapped scope=ok_for_propagation_to_go→GO:0006614 (SRP-dependent cotranslational protein targeting to membrane); class `Protein transport`=mapped→GO:0015031; branch=no_mapping.
- **Consistency:** Strong and mutually consistent. Deep research, review YAML, and PN annotation all describe SRP19 as the 19 kDa SRP subunit that binds 7SL RNA (clamping helices 6/8), gating SRP54 incorporation and S-domain assembly. The PN "SRP component" label and GO:0006614 mapping match the review's core BP (GO:0006614 IEA, ACCEPT; plus the signal-sequence-recognition child GO:0006617). No contradictions.
- **PN story / NEW pressure:** PN asserts only the canonical SRP cotranslational-targeting role, already captured (GO:0006614, GO:0006617, GO:0008312 7S RNA binding, GO:0005786 SRP membership). Nuclear/nucleolar assembly localizations (GO:0005730/0005654, kept non-core) and the disease/autoantigen context (PMID:35754847) are in the review but outside the PN story. Conclusion: **already captured** (no NEW pressure).
- **Mapping strategy:** No change needed. GO:0006614 (goa_status already_in_goa_exact) is present and ACCEPTed — exact projection, not broader than the review. The class-level GO:0015031 is a broad class target, not asserted of SRP19 specifically.
- **Evidence alignment:** PN dossier lists no reference titles; alignment via projected-term provenance. Review's core support (PMID:27899666 SRP72/19 RNA-remodeling structures; PMID:12086622 SRP19 helix-6/8 clamp; PMID:10618370 ordered SRP54-late assembly; PMID:34208095 SRP review) all encode the SRP cotranslational-targeting biology the PN maps to. No divergence.
- **Verdict:** Fully consistent; PN already captured, review more granular (adds 7S RNA binding and signal-sequence-recognition child). No edits warranted.