## TRAPPC13
- **UniProt:** A5PLN9 · **batch:** proteostasis-pr-1217 · **review status:** COMPLETE
- **PN placement:** `Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component` ; **PN-node mapping:** type-leaf mapped, scope=ok_for_propagation_to_go, GO:0030008 TRAPP complex (entailed_by_goa_closure)
- **Consistency:** Coherent. Notes, review YAML, PN annotation, and node mapping all agree TRAPPC13 (Trs65 homolog) is a large TRAPP subunit acting via complex-level RAB1 GEF/ER-to-Golgi trafficking, not an independent autophagy effector. PN row labels it "TRAPP III, specific subunit"; review carries both TRAPPII (GO:1990071) and TRAPPIII (GO:1990072) memberships with an explicit caveat about source-dependent partition — a documented nuance, not a contradiction. No PMIDs misattributed.
- **PN story / NEW pressure:** PN Notes assert ATG9/ATG2 trafficking + TRAPP-III autophagy role. Review correctly resists converting this into a TRAPPC13-specific autophagy BP: the cited TRAPP review states the mammalian TRAPP-III/autophagy link "is currently not clear" (PMID:27066478). No defensible gene-specific NEW autophagy term; the PN autophagy context is already captured by TRAPPIII membership (GO:1990072, whose OLS definition itself notes it "regulates autophagy"). Conclusion: already captured.
- **Mapping strategy:** No change needed. Projected GO:0030008 (OLS-verified) is entailed by GOA closure (review carries the subclasses GO:1990071/1990072). Component-bucket scope is correct and not over-broad.
- **Evidence alignment:** PN titles = "Membrane Trafficking in Autophagy", the TRAPP review (PMID:27066478, in review), and "TRAPPC13 modulates autophagy and the response to Golgi stress" (a TRAPPC13-specific JCS paper NOT cited in the review). Otherwise overlapping.
- **Verdict:** Consistent; ACCEPT mapping. Minor gap: a TRAPPC13-specific autophagy/Golgi-stress paper in the PN row is absent from review references.
- **Recommended edits:** Consider adding the PN-listed "TRAPPC13 modulates autophagy and the response to Golgi stress" (J Cell Sci) to references and assess whether it strengthens (or still does not justify) a gene-specific autophagy annotation.