## TRAPPC3
- **UniProt:** O43617 · **batch:** proteostasis-pr-1217 · **review status:** COMPLETE
- **PN placement:** `Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component` ; **PN-node mapping:** type-leaf mapped, scope=ok_for_propagation_to_go, GO:0030008 TRAPP complex (already_in_goa_exact)
- **Consistency:** Coherent. Notes, review, PN row ("TRAPP complex, core subunit"), and node mapping all agree TRAPPC3/Bet3 is a core TRAPP subunit contributing complex-level RAB1 GEF activity and ER-to-Golgi transport. Review carries GO:0030008 (IDA, IBA, IEA) plus contributes_to GO:0005085, consistent with PN. No contradictions; 13 generic protein-binding rows uniformly MARK_AS_OVER_ANNOTATED.
- **PN story / NEW pressure:** PN Notes mention ATG9/ATG2 trafficking. Review keeps autophagy as TRAPPIII-membership context only (no autophagy BP), citing PMID:27066478 "connection ... not clear." Defensible — no gene-specific autophagy evidence for the core subunit. Conclusion: already captured via complex membership.
- **Mapping strategy:** No change. GO:0030008 (OLS-verified) is already in GOA exactly; the projected term matches review. Scope correct.
- **Evidence alignment:** Strong overlap. PN titles ("Membrane Trafficking in Autophagy"; PMID:27066478) both present in review. Review adds substantial primary literature beyond the PN row (PMID:16828797 Bet3-Tpc6B structure, PMID:21525244, PMID:18930054, Reactome). No divergence/miscitation.
- **Verdict:** Consistent; ACCEPT mapping. Cleanest gene-level representation of the PN TRAPP-component leaf; review is more richly evidenced than the PN row.
- **Recommended edits:** None required.