## TRIP4
- **UniProt:** Q15650 · **batch:** proteostasis-batch-2026-06-07c · **review status:** complete (all annotations actioned; 2 core_functions)
- **PN placement:** `Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue` (also a UPS "idiosyncratic Ub binding / other" taxonomy row) ; **PN-node mapping:** type=mapped scope=ok_for_propagation_to_go GO:0072344 (rescue of stalled cytosolic ribosome); group=mapped GO:0006515.
- **Consistency:** Strong. Notes, review and PN all describe the dual ASC-1/RQT (RQC) + nuclear coactivator roles. Review ACCEPTs GO:0072344 (5x in GOA, IDA/IBA) and the RQT-complex/ribosome-disassembly terms; core_functions name GO:0072344 + GO:0003713. No contradictions. The UPS row maps to no_mapping (correct — taxonomy only).
- **PN story / NEW pressure:** PN's RQC role is already richly captured in GOA/review (GO:0072344, GO:0180022 RQC-trigger complex, GO:0032790 ribosome disassembly, GO:1990116). The PN group-level GO:0006515 (verified real; PQC for misfolded/incompletely synthesized proteins) is projected new_to_goa but is a broad QC umbrella; for TRIP4 the more specific GO:1990116 (already annotated) is the better representation. Conclusion: **already captured**; GO:0006515 over-reaches relative to existing specific terms.
- **Mapping strategy:** TRIP4 does not change the node. The "Ribosomal rescue" subtype→GO:0072344 mapping is exact and well supported here; the parent group→GO:0006515 is broader than what TRIP4 (and GO) actually uses (GO:1990116), so it should stay context/propagation-only, not displace the specific terms.
- **Evidence alignment:** PN cites only PMID:36627279 (yeast RQT4 analogy, "/rev"); not in the review YAML, but the review relies on direct human RQT papers (PMID:32579943, 36302773). Divergence is benign — PN row is a family/analogy citation.
- **Verdict:** Consistent; PN RQC story already captured by specific GO terms. GO:0006515 is broader than TRIP4's annotated GO:1990116 — keep as propagation-context only, do not add.
