## UFM1
- **UniProt:** P61960 · **batch:** proteostasis-batch-2026-06-07c · **review status:** complete (core MF GO:0031386 protein tag activity; many IPI/protein-binding rows triaged)
- **PN placement:** `Translation|Cytosolic translation|Ribosome-associated QC|UFMylation`; `ALP|...|ERphagy|UFMylation of ER proteins`; `UPS|Ubiquitin and UBL proteins|ubiquitin-like modifier|UFM1` ; **PN-node mapping:** UFMylation type→GO:0071569; ERphagy→GO:0061709; UBL-modifier type & group→no_mapping (correct — UFM1 is the tag, not an enzyme); class→context-only GO:0019787.
- **Consistency:** Strong. Notes/review/PN agree UFM1 is the modifier (not an enzyme), conjugated via Gly-83 isopeptide bond; principal substrate RPL26. Review ACCEPTs GO:0071569 (multiple), GO:1990592 (K69-linked ufmylation, IDA), cytoplasm; ER-stress/reticulophagy/brain-development/ER-signaling KEEP_AS_NON_CORE; two MARK_AS_OVER_ANNOTATED (neg reg apoptosis, neg reg nuclear import). No contradictions.
- **PN story / NEW pressure:** All PN assertions captured. The review's core MF GO:0031386 (protein tag activity; verified real) is a curatorial assignment NOT in GOA (UFM1 GOA MF rows are only GO:0005515 IPI) — this is the one defensible **ADD** candidate, well-justified for a UBL tag. GO:0006515 (verified) projected new_to_goa via RQC group is broad and not a direct fit for the modifier itself. Conclusion: ufmylation/ERphagy already captured; GO:0031386 a sound add at MF; GO:0006515 over-reaches.
- **Mapping strategy:** PN appropriately gives the UBL-modifier nodes no_mapping (a tag is not a transferase) and keeps GO:0019787 as class context only — consistent with the review using GO:0031386. UFM1 does not change the node.
- **Evidence alignment:** PN row 3 cites "28234446 / rev" (review article, not in review YAML); review uses PMID:15071506, 30626644, 25219498 etc. PN ERphagy row cites the screen (PMID:32160526, in notes). Core ufmylation evidence overlaps thematically; PN's family-review PMID is non-overlapping by design.
- **Verdict:** Consistent and complete; PN story fully captured. GO:0031386 protein tag activity is a justified MF add (curatorial, absent from GOA); GO:0006515 not warranted as a direct UFM1 term.
