gene_symbol	gene_name	target_go_id	target_go_label	goa_status	mapping_scopes	mapping_files	mapping_subjects	pn_codes	representative_genes	supporting_goa_terms	projection_count
AAAS		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
AAAS		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
AARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
AARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
AATF		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	BOP1;DDX27;PELP1;PES1;WDR12		1
AATF		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
ABCE1		GO:0006415	translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Ribosome splitting	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0006415 translational termination	1
ABCE1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ABCE1		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
ABCF2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ABHD6		GO:0016298	lipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	ABHD6;DAGLB;LIPA	GO:0004620 glycerophospholipase activity;GO:0047372 monoacylglycerol lipase activity	1
ABRAXAS1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
ABRAXAS1		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|BRCA1-A complex component|idiosyncratic Ub binding / MPN	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006302 double-strand break repair	1
ABRAXAS1		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
ABRAXAS2		GO:0006281	DNA repair	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|BRISC complex component|idiosyncratic Ub binding / MPN	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH		1
ABRAXAS2		GO:0070552	BRISC complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic|JAMM / MPN / ubiquitin binding	ABRAXAS2;BABAM1;BABAM2;BRCC3	GO:0070552 BRISC complex	2
ABTB1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|ankyrin	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
ABTB2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|ankyrin	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
ABTB3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|ankyrin, transmembrane	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
ACBD5		GO:0000425	pexophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Pexophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Pexophagy	ACBD5	GO:0000425 pexophagy	1
ACP2		GO:0016791	phosphatase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	ACP2;ACP3;ACP4;ACP5	GO:0003993 acid phosphatase activity	1
ACP3		GO:0016791	phosphatase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	ACP2;ACP3;ACP4;ACP5	GO:0016791 phosphatase activity	1
ACP4		GO:0016791	phosphatase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	ACP2;ACP3;ACP4;ACP5	GO:0003993 acid phosphatase activity;GO:0004725 protein tyrosine phosphatase activity	1
ACP5		GO:0016791	phosphatase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal phosphatase	ACP2;ACP3;ACP4;ACP5	GO:0003993 acid phosphatase activity	1
ADRB2		GO:0061724	lipophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy|Upstream lipophagy signaling	ADRB2;AUP1;RAB7A;RAB7B;UBE2G2	GO:1904504 positive regulation of lipophagy	1
ADRM1		GO:0000502	proteasome complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / PRU	ADRM1;PSMD14;PSMD2;PSMD4	GO:0000502 proteasome complex	1
ADRM1		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / PRU	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|PRU, DEUBAD;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / PRU	ADRM1;PSMC1;PSMC2;PSMC3;PSMC4;PSMC5;PSMD14;PSMD2;PSMD4	GO:0008541 proteasome regulatory particle, lid subcomplex	3
ADRM1		GO:0008540	proteasome regulatory particle, base subcomplex	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|PRU, DEUBAD	ADRM1;PSMD1;PSMD2;PSMD4	GO:0000502 proteasome complex	1
AFG3L2		GO:0005759	mitochondrial matrix	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005739 mitochondrion	1
AFG3L2		GO:0035694	mitochondrial protein catabolic process	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0030163 protein catabolic process	1
AGA		GO:0003948	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal protein deglycosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal protein deglycosidase	AGA	GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	1
AGK		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
AGK		GO:0042721	TIM22 mitochondrial import inner membrane insertion complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	AGK;TIMM22;TIMM29	GO:0042721 TIM22 mitochondrial import inner membrane insertion complex	1
AGR2		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
AGR3		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
AHCTF1		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
AHCTF1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
AHR		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|AHR / ARNT / TBL3 complex|PAS	AHR;ARNT;COP1;DCAF13;DCAF7		1
AHSA1		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
AIMP1		GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|multisynthase complex	Translation|Cytosolic translation|Translation elongation|multisynthase complex	AIMP1;AIMP2;EEF1E1	GO:0017101 aminoacyl-tRNA synthetase multienzyme complex	1
AIMP2		GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|multisynthase complex	Translation|Cytosolic translation|Translation elongation|multisynthase complex	AIMP1;AIMP2;EEF1E1	GO:0017101 aminoacyl-tRNA synthetase multienzyme complex	1
AIP		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
AIP		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and PPIase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
AIPL1		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
AIPL1		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and PPIase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
AIRE		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|other	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1		1
AKIRIN1		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|Akirin	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
AKIRIN2		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|Akirin	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
AKT1		GO:1904715	negative regulation of chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Modulator of LAMP2A multimerization	AKT1;CTSA;RICTOR	GO:0010507 negative regulation of autophagy	1
AKT1S1		GO:0031931	TORC1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR	GO:0031931 TORC1 complex	1
AMBRA1		GO:1904716	positive regulation of chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Enhancer of substrate uptake	AMBRA1;GFAP;MT-RNR2;PSME1;TP53	GO:0010508 positive regulation of autophagy	1
AMBRA1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
AMFR		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|LMBR1L-GP78-UBAC2 complex|catalytic / UBOX, transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
AMFR		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
AMFR		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding & transmembrane|ER;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD & TM|CUE;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases|RING|VIM & transmembrane	AMFR;ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;RNF125;RNF31;SYVN1;TRIM36;TRIM46;TRIM9;UBE4B	GO:0061630 ubiquitin protein ligase activity	3
ANAPC1		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / Armadillo-like	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC1		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / Armadillo-like	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC10		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / DOC	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC10		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / DOC	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC11		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|catalytic / RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component|APC / catalytic subunit|idiosyncratic Ub binding / other	ANAPC11;ANAPC2;FANCL;GID8;KCMF1;MAEA;RANBP10;RMND5A;RMND5B;SHARPIN	GO:0005680 anaphase-promoting complex;GO:0031461 cullin-RING ubiquitin ligase complex	2
ANAPC11		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|catalytic / RING	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC13		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC13		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC15		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC15		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC16		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC16		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC2		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|catalytic / core;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component|APC / catalytic subunit|idiosyncratic Ub binding / other	ANAPC11;ANAPC2;FANCL;GID8;KCMF1;MAEA;RANBP10;RMND5A;RMND5B;SHARPIN	GO:0005680 anaphase-promoting complex;GO:0031461 cullin-RING ubiquitin ligase complex	2
ANAPC2		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|catalytic / core	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC2		GO:0160072	ubiquitin ligase complex scaffold activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|degenerate, APC sununit	CUL1;CUL2;CUL3;CUL4A;CUL4B		1
ANAPC4		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC4		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / WD40	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC5		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC5		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANAPC7		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
ANAPC7		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
ANKFY1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|ankyrin	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
ANKIB1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|Ariadne, ankyrin repeats, UIM;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / Ariadne|UIM, UBA-like (ARIH1)	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
ANKZF1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|VCP system for RQC	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0006515 protein quality control for misfolded or incompletely synthesized proteins	1
ANKZF1		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Vms pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
ANP32E		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
APOO		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
APOOL		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
APPBP2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|TPR	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
ARCN1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
ARCN1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
ARCN1		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
AREL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|FIL	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
ARF1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	COPA;COPB1;COPB2;COPE;COPG1	GO:0016192 vesicle-mediated transport	1
ARF1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
ARF1		GO:0030126	COPI vesicle coat	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	ARF1;GBF1	GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0012505 endomembrane system;GO:0032991 protein-containing complex	1
ARIH1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|Ariadne;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / Ariadne|UBA-like (ARIH1)	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
ARIH2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|Ariadne;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / Ariadne|UBA-like (ARIH1)	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
ARK2C		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ARL8A		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3;RUFY4		3
ARL8B		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3;RUFY4		3
ARMC5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / other|Armadillo-like	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
ARMC8		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / Armadillo-like	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
ARNT		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|AHR / ARNT / TBL3 complex|PAS	AHR;ARNT;COP1;DCAF13;DCAF7		1
ARSA		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
ARSB		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
ARSD		GO:0008484	sulfuric ester hydrolase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0004065 arylsulfatase activity	1
ARSG		GO:0008484	sulfuric ester hydrolase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0004065 arylsulfatase activity;GO:0033889 N-sulfoglucosamine-3-sulfatase activity	1
ASB2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|CUL5 receptor|UIM	ASB2;FBXW4;FBXW7;FBXW8;PML	GO:0061630 ubiquitin protein ligase activity	1
ASCC1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ASCC1		GO:0072344	rescue of stalled cytosolic ribosome	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ASCC2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ASCC2		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
ASCC3		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ASCC3		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
ASF1A		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
ASF1B		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
ATAD1		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|mitoCPR pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
ATAD3A		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
ATF3		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
ATF3		GO:0140467	integrated stress response signaling	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Integrated stress response;PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	ATF3;ATF4;DDIT3		2
ATF4		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF4 transcriptional program|Transcription factor;PN regulation|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF4 transcriptional program|Transcription factor;PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	ATF4;HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	2
ATF4		GO:0140467	integrated stress response signaling	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Integrated stress response;PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	ATF3;ATF4;DDIT3	GO:0140467 integrated stress response signaling	2
ATF5		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF5 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF5 transcriptional program|Transcription factor	ATF5	GO:0003700 DNA-binding transcription factor activity	1
ATF6		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF6/CEBPB transcriptional program|Transcription factor;PN regulation|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF6/CEBPB transcriptional program|Transcription factor;PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	ATF6;CEBPB;HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	2
ATF6		GO:0006986	response to unfolded protein	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	ATF6;XBP1	GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036500 ATF6-mediated unfolded protein response	1
ATF6		GO:0030968	endoplasmic reticulum unfolded protein response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Unfolded protein response	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	ATF6;XBP1	GO:0030968 endoplasmic reticulum unfolded protein response	1
ATG10		GO:0032446	protein modification by small protein conjugation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Processing of ATG5-ATG12-ATG16 complex components	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Processing of ATG5-ATG12-ATG16 complex components	ATG10;ATG7	GO:0032446 protein modification by small protein conjugation	1
ATG101		GO:1990316	Atg1/ULK1 kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:1990316 Atg1/ULK1 kinase complex	1
ATG12		GO:0034274	Atg12-Atg5-Atg16 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	ATG12;ATG16L1;ATG16L2;ATG5	GO:0034274 Atg12-Atg5-Atg16 complex	1
ATG13		GO:1990316	Atg1/ULK1 kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:1990316 Atg1/ULK1 kinase complex	1
ATG14		GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	ATG14;BECN1;BECN2;PIK3C3;PIK3R4	GO:0032991 protein-containing complex;GO:0035032 phosphatidylinositol 3-kinase complex, class III	1
ATG16L1		GO:0034274	Atg12-Atg5-Atg16 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	ATG12;ATG16L1;ATG16L2;ATG5	GO:0034274 Atg12-Atg5-Atg16 complex	1
ATG16L2		GO:0034274	Atg12-Atg5-Atg16 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	ATG12;ATG16L1;ATG16L2;ATG5	GO:0034274 Atg12-Atg5-Atg16 complex	1
ATG2A		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0034045 phagophore assembly site membrane	1
ATG2B		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0034045 phagophore assembly site membrane	1
ATG3		GO:0141046	Atg8-family conjugating enzyme activity	already_in_goa_exact	exact	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|E2-like enzyme conjugated to ATG8 before transfer to PE	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|E2-like enzyme conjugated to ATG8 before transfer to PE	ATG3	GO:0141046 Atg8-family conjugating enzyme activity	1
ATG4A		GO:0008234	cysteine-type peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;ubiquitin_proteasome_system.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease|with LIR	ATG4A;ATG4B;ATG4C;ATG4D	GO:0008234 cysteine-type peptidase activity	2
ATG4A		GO:0051697	protein delipidation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	ATG4A;ATG4B;ATG4C;ATG4D	GO:0051697 protein delipidation	1
ATG4B		GO:0008234	cysteine-type peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;ubiquitin_proteasome_system.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease|with LIR	ATG4A;ATG4B;ATG4C;ATG4D	GO:0008234 cysteine-type peptidase activity	2
ATG4B		GO:0051697	protein delipidation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	ATG4A;ATG4B;ATG4C;ATG4D	GO:0051697 protein delipidation	1
ATG4C		GO:0008234	cysteine-type peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;ubiquitin_proteasome_system.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease|with LIR	ATG4A;ATG4B;ATG4C;ATG4D	GO:0008234 cysteine-type peptidase activity	2
ATG4C		GO:0051697	protein delipidation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	ATG4A;ATG4B;ATG4C;ATG4D	GO:0051697 protein delipidation	1
ATG4D		GO:0008234	cysteine-type peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;ubiquitin_proteasome_system.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Protease that removes C-terminal Arg from ATG8;Ubiquitin Proteasome System|DUBs and UBL demodifiers|ATG4 cysteine protease|lacking LIR	ATG4A;ATG4B;ATG4C;ATG4D	GO:0008234 cysteine-type peptidase activity	2
ATG4D		GO:0051697	protein delipidation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Regulation of autophagosome membrane composition|ATG8 homolog de-lipidation|Releases ATG8 homologs from maturing autophagosome	ATG4A;ATG4B;ATG4C;ATG4D	GO:0051697 protein delipidation	1
ATG5		GO:0034274	Atg12-Atg5-Atg16 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|Component of E3-like ATG5-ATG12-ATG16 complex that transfers ATG8 to PE	ATG12;ATG16L1;ATG16L2;ATG5	GO:0034274 Atg12-Atg5-Atg16 complex	1
ATG7		GO:0019778	Atg12 activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of ATG8, ATG12	Ubiquitin Proteasome System|E1 activating enzymes|activation of ATG8, ATG12	ATG7	GO:0019778 Atg12 activating enzyme activity	1
ATG7		GO:0032446	protein modification by small protein conjugation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Processing of ATG5-ATG12-ATG16 complex components	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Processing of ATG5-ATG12-ATG16 complex components	ATG10;ATG7	GO:0032446 protein modification by small protein conjugation	1
ATG9A		GO:0017128	phospholipid scramblase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG9 homolog	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG9 homolog	ATG9A;ATG9B	GO:0017128 phospholipid scramblase activity	1
ATG9B		GO:0017128	phospholipid scramblase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG9 homolog	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG9 homolog	ATG9A;ATG9B	GO:0017128 phospholipid scramblase activity	1
ATL3		GO:0061709	reticulophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62		1
ATP13A1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Removal of misinserted transmembrane proteins	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
ATP23		GO:0005758	mitochondrial intermembrane space	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ATP23;HTRA2;NLN	GO:0005739 mitochondrion	1
ATP23		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
ATP6AP1		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6AP1		GO:0060590	ATPase regulator activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump;Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Regulator of the lysosomal v-ATPase proton pump	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump;Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Regulator of the lysosomal v-ATPase proton pump	ATP6AP1;ATP6AP2;LRRK2		2
ATP6AP2		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6AP2		GO:0060590	ATPase regulator activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump;Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Regulator of the lysosomal v-ATPase proton pump	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump;Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Regulator of the lysosomal v-ATPase proton pump	ATP6AP1;ATP6AP2;LRRK2		2
ATP6V0A1		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V0A1		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0A1		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005737 cytoplasm;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0A2		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification	1
ATP6V0A2		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0A2		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0A4		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0006885 regulation of pH;GO:0007035 vacuolar acidification;GO:0051452 intracellular pH reduction	1
ATP6V0A4		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0A4		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0B		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V0B		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0B		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0033176 proton-transporting V-type ATPase complex;GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0C		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V0C		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0C		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0033176 proton-transporting V-type ATPase complex;GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain;GO:0033179 proton-transporting V-type ATPase, V0 domain;GO:0046611 lysosomal proton-transporting V-type ATPase complex;GO:0098588 bounding membrane of organelle	1
ATP6V0D1		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification;GO:0042592 homeostatic process	1
ATP6V0D1		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0D1		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0032991 protein-containing complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain;GO:0046611 lysosomal proton-transporting V-type ATPase complex	1
ATP6V0D2		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification	1
ATP6V0D2		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0D2		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0E1		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification	1
ATP6V0E1		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0E1		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0E2		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification	1
ATP6V0E2		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V0E2		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
ATP6V1A		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V1A		GO:0033176	proton-transporting V-type ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0033176 proton-transporting V-type ATPase complex	1
ATP6V1A		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0005774 vacuolar membrane;GO:0016020 membrane;GO:0016469 proton-transporting two-sector ATPase complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain;GO:0046611 lysosomal proton-transporting V-type ATPase complex	1
ATP6V1B1		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0006885 regulation of pH;GO:0007035 vacuolar acidification	1
ATP6V1B1		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1B1		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1B2		GO:0007042	lysosomal lumen acidification	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007035 vacuolar acidification	1
ATP6V1B2		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1B2		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005737 cytoplasm;GO:0005765 lysosomal membrane;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1C1		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1C1		GO:0033176	proton-transporting V-type ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0033176 proton-transporting V-type ATPase complex	1
ATP6V1C1		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016469 proton-transporting two-sector ATPase complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1C2		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1C2		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1C2		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1D		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V1D		GO:0033176	proton-transporting V-type ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0033176 proton-transporting V-type ATPase complex	1
ATP6V1D		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0033176 proton-transporting V-type ATPase complex;GO:0046611 lysosomal proton-transporting V-type ATPase complex	1
ATP6V1E1		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1E1		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0046611 lysosomal proton-transporting V-type ATPase complex	1
ATP6V1E1		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0005774 vacuolar membrane;GO:0016469 proton-transporting two-sector ATPase complex;GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain;GO:0046611 lysosomal proton-transporting V-type ATPase complex	1
ATP6V1E2		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1E2		GO:0033176	proton-transporting V-type ATPase complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2		1
ATP6V1E2		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0005774 vacuolar membrane;GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain	1
ATP6V1F		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V1F		GO:0033176	proton-transporting V-type ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0033176 proton-transporting V-type ATPase complex	1
ATP6V1F		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1G1		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1G1		GO:0033176	proton-transporting V-type ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0033176 proton-transporting V-type ATPase complex	1
ATP6V1G1		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033176 proton-transporting V-type ATPase complex;GO:0033180 proton-transporting V-type ATPase, V1 domain	1
ATP6V1G2		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1G2		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0016471 vacuolar proton-transporting V-type ATPase complex	1
ATP6V1G2		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0016471 vacuolar proton-transporting V-type ATPase complex	1
ATP6V1G3		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
ATP6V1G3		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0016471 vacuolar proton-transporting V-type ATPase complex	1
ATP6V1G3		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0016471 vacuolar proton-transporting V-type ATPase complex	1
ATP6V1H		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
ATP6V1H		GO:0033176	proton-transporting V-type ATPase complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain	1
ATP6V1H		GO:0046612	lysosomal proton-transporting V-type ATPase, V1 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V1 lysosomal v-ATPase proton pump component	ATP6V1A;ATP6V1B1;ATP6V1B2;ATP6V1C1;ATP6V1C2	GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain;GO:0005765 lysosomal membrane;GO:0016020 membrane	1
ATRIP		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA damage signalling|idiosyncratic Ub binding / other	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
ATRX		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
ATXN3		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin|UIM	ATXN3;ATXN3L;JOSD1;JOSD2	GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
ATXN3L		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin|UIM	ATXN3;ATXN3L;JOSD1;JOSD2	GO:0004843 cysteine-type deubiquitinase activity	1
AUP1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
AUP1		GO:0061724	lipophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy|Ubiquitination of lipid droplet surface proteins	ADRB2;AUP1;RAB7A;RAB7B;UBE2G2	GO:0061724 lipophagy	1
AUP1		GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein quality control|ERAD cofactor	Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein quality control|ERAD cofactor|CUE	AUP1;UFD1	GO:0036503 ERAD pathway	1
AZI2		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Xenophagy	AZI2;LGALS8		1
BABAM1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|other / RCC1, SPRY, WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
BABAM1		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|other / RCC1, SPRY, WD40	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
BABAM1		GO:0070552	BRISC complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic|other / RCC1, SPRY, WD40	ABRAXAS2;BABAM1;BABAM2;BRCC3	GO:0070552 BRISC complex	2
BABAM2		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000152 nuclear ubiquitin ligase complex	1
BABAM2		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|BRCA1-A complex component|idiosyncratic Ub binding / other	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006302 double-strand break repair	1
BABAM2		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
BABAM2		GO:0070552	BRISC complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|noncatalytic|ubiquitin binding	ABRAXAS2;BABAM1;BABAM2;BRCC3	GO:0070552 BRISC complex	2
BAG1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|BAG domain subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
BAG2		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|BAG domain subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
BAG2		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|BAG	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
BAG3		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|BAG domain subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
BAG3		GO:0035973	aggrephagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	BAG3;HSPA8;HSPB8;STUB1	GO:1905337 positive regulation of aggrephagy	1
BAG4		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|BAG domain subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
BAG5		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|BAG domain subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
BAG6		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane	1
BAP1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	BAP1;UCHL1;UCHL3;UCHL5	GO:0004843 cysteine-type deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity	1
BARD1		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1/BARD complex|catalytic / RING	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
BARD1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BRCA1 & associated|BRCT;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BRCA1 & associated|idiosyncratic Ub binding / other	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
BAZ1B		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|kinase, bromodomain	MID1;MID2;TRIM36;TRIM46;TRIM9		1
BCAP31		GO:0036503	ERAD pathway	more_specific_than_existing_goa	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0034976 response to endoplasmic reticulum stress	1
BCCIP		GO:0000027	ribosomal large subunit assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	BCCIP;RSL24D1		1
BCCIP		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	AATF;IMP3;NOP56;UTP4		1
BCL2L13		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
BECN1		GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	ATG14;BECN1;BECN2;PIK3C3;PIK3R4	GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I	1
BECN1		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG	GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II	1
BECN2		GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	ATG14;BECN1;BECN2;PIK3C3;PIK3R4	GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I	1
BFAR		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
BIRC2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BIRC / IAP|BIR repeat;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BIRC, IAP|UBA (BIRC2/3)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
BIRC3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BIRC / IAP|BIR repeat;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BIRC, IAP|UBA (BIRC2/3)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
BIRC6		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|E3 with intrinsic E2	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|E3 with intrinsic E2|BIR repeat	BIRC6;UBE2O	GO:0004842 ubiquitin-protein transferase activity	1
BIRC6		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 14|E2-E3 chimera	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 14|E2-E3 chimera	BIRC6;UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2O	GO:0061631 ubiquitin conjugating enzyme activity	2
BIRC7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BIRC / IAP|BIR repeat	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
BIRC8		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BIRC / IAP|BIR repeat;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BIRC, IAP|UBA (BIRC2/3)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
BLOC1S1		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BLOC1S2		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BMAL1		GO:1904715	negative regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Negative regulator of transcription of CMA components	BMAL1;RAB11A;RARA		1
BMI1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9		2
BMS1		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|RCL1-BMS1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
BMS1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|RCL1-BMS1 complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
BNIP1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1		1
BNIP3		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0000423 mitophagy	1
BNIP3L		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:1901524 regulation of mitophagy	1
BOP1		GO:0030687	preribosome, large subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:0030687 preribosome, large subunit precursor	1
BOP1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
BORCS5		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BORCS6		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BORCS7		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BORCS8		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
BRAP		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BRCA1 & associated|UBP-type ZnF;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BRCA1 & associated|UBP-associated ZnF	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
BRCA1		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|catalytic / RING;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-B complex|catalytic / RING;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-C complex|catalytic / RING;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1/BARD complex|catalytic / RING	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	4
BRCA1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BRCA1 & associated|BRCT	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
BRCA1		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|catalytic / RING	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
BRCC3		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|DUB / MPN	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
BRCC3		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|DUB / MPN	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
BRCC3		GO:0070552	BRISC complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|catalytic subunit|JAMM / MPN	ABRAXAS2;BABAM1;BABAM2;BRCC3	GO:0070552 BRISC complex	1
BRCC3		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|catalytic subunit;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	Ubiquitin Proteasome System|DUBs and UBL demodifiers|BRISC complex|catalytic subunit|JAMM / MPN;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	BRCC3;MPND;MYSM1	GO:0140492 metal-dependent deubiquitinase activity	2
BRIP1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-B complex|DNA helicase	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
BRWD1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|bromodomain	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
BRWD3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|bromodomain	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
BTBD1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|PHR	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD16		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD19		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	no_local_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|PHR	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|PHR	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|PHR	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTBD9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
BTF3		GO:0005854	nascent polypeptide-associated complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	BTF3;NACA;NACA2;NACAD	GO:0005854 nascent polypeptide-associated complex	1
BTRC		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
BUD23		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0070476 rRNA (guanine-N7)-methylation	1
BUD23		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
BUD23		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex;Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0070476 rRNA (guanine-N7)-methylation	2
BYSL		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
BYSL		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
BZW1		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
BZW1		GO:0006413	translational initiation	supported_by_goa_regulation	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006446 regulation of translational initiation	1
BZW2		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
BZW2		GO:0006413	translational initiation	supported_by_goa_regulation	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006446 regulation of translational initiation	1
C10orf90		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|other	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
CABIN1		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
CACUL1		GO:0160072	ubiquitin ligase complex scaffold activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|degenerate, possible CUL3 inhibitor	CUL1;CUL2;CUL3;CUL4A;CUL4B		1
CACYBP		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
CALCOCO1		GO:0061709	reticulophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62		1
CALCOCO2		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Mitophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Mitophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;RABGEF1;SQSTM1;TAX1BP1		2
CALCOCO2		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	ARL8A;ARL8B;CALCOCO2;MAP1LC3B;MYO6;RILP;RUFY3;TAX1BP1;TOM1		2
CALCOCO2		GO:0098792	xenophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	CALCOCO2;OPTN;SQSTM1;TAX1BP1;TRIM5	GO:0098792 xenophagy	1
CALCOCO2		GO:0160247	autophagy cargo adaptor activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Lysophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Lysophagy	CALCOCO2;TRIM16		1
CALM1		GO:0000151	ubiquitin ligase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex|UBR4/KCMF1 complex|noncatalytic subunit	CALM1;KCMF1;UBR4	GO:0032991 protein-containing complex;GO:1902494 catalytic complex	1
CALR		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
CALR3		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
CAMKK2		GO:0004674	protein serine/threonine kinase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|AMPK kinase (not in a complex)	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|AMPK kinase (not in a complex)	CAMKK2;MAP3K7	GO:0004674 protein serine/threonine kinase activity	1
CAMLG		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	CAMLG;FKBP2;FKBP7;PPIB;PPIC		2
CAMLG		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA		1
CAMLG		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
CAND1		GO:1990757	ubiquitin ligase activator activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor|Armadillo-like	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor|Armadillo-like	CAND1;CAND2		2
CAND2		GO:1990757	ubiquitin ligase activator activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor|Armadillo-like	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|F-box exchange factor|Armadillo-like	CAND1;CAND2		2
CANX		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
CARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
CARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
CASQ1		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
CASQ2		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
CBL		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|CBL|PTB, UBA;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / CBL|UBA	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
CBLB		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|CBL|PTB, UBA;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / CBL|UBA	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
CBLC		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|CBL|PTB	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CBLL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Hakai	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CBLL2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Hakai	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CCDC47		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
CCDC47		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
CCDC47		GO:0160005	PAT complex	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	CCDC47;WDR83OS	GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane	1
CCDC50		GO:0160247	autophagy cargo adaptor activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Individual substrates	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Individual substrates	CCDC50;MEFV		1
CCIN		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
CCNB1IP1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CCNF		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
CCPG1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
CCT2		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT3		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT4		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT5		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT6A		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT6B		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT7		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT8		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CCT8L2		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
CDC16		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC16		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC20		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC20		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC20B		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC20B		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC23		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC23		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC26		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC26		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / other	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC27		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
CDC27		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|noncatalytic / TPR	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
CDC34		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain & C-terminal extension	CDC34;UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2R2	GO:0061631 ubiquitin conjugating enzyme activity	2
CDC37		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
CDC37L1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding;GO:0031072 heat shock protein binding	1
CDK5RAP3		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
CDK5RAP3		GO:0061709	reticulophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0140501 positive regulation of reticulophagy	1
CDK5RAP3		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
CEBPB		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF6/CEBPB transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|ATF6/CEBPB transcriptional program|Transcription factor	ATF6;CEBPB	GO:0003700 DNA-binding transcription factor activity	1
CEP55		GO:0000281	mitotic cytokinesis	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mitotic exit and cytokinesis	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mitotic exit and cytokinesis|mitotic exit and cytokinesis|UBAN-like, UBZ-like	CEP55	GO:0000281 mitotic cytokinesis	1
CGRRF1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
CHAF1A		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
CHAF1B		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
CHCHD3		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
CHCHD4		GO:0061617	MICOS complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0005739 mitochondrion	1
CHCHD4		GO:0160203	mitochondrial disulfide relay system	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Folding enzyme|Protein disulfide isomerases	Mitochondrial proteostasis|Folding enzyme|Protein disulfide isomerases	CHCHD4;GFER	GO:0160203 mitochondrial disulfide relay system	1
CHCHD6		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
CHD3		GO:0006338	chromatin remodeling	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling|SIM	CHD3;RSF1;SMARCAD1	GO:0006338 chromatin remodeling	1
CHFR		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CHIC2		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic UBOX complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic UBOX complex|STUB1/CHIC2 complex|noncatalytic	CHIC2;STUB1		1
CHIT1		GO:0016798	hydrolase activity, acting on glycosyl bonds	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal chitobiase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal chitobiase	CHIT1;CTBS	GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0004568 chitinase activity;GO:0008843 endochitinase activity	1
CHMP1A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy	1
CHMP1A		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP1B		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy	1
CHMP1B		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP2A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP2A		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP2B		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP2B		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP3		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP3		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP4A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP4A		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP4B		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP4B		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP4C		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP4C		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP5		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy	1
CHMP5		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP6		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
CHMP6		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHMP7		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy	1
CHMP7		GO:0000815	ESCRT III complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex component;Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0000815 ESCRT III complex	2
CHORDC1		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
CHUK		GO:0008385	IkappaB kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	CHUK;IKBKB;IKBKG;MAP3K7	GO:0008385 IkappaB kinase complex	1
CLCN7		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Miscellaneous function - lysosomal acidification	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
CLEC16A		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000423 mitophagy	1
CLGN		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
CLPB		GO:0140545	ATP-dependent protein disaggregase activity	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP100 disaggregase	Mitochondrial proteostasis|Chaperone|HSP100 disaggregase	CLPB	GO:0140545 ATP-dependent protein disaggregase activity	1
CLPP		GO:0005759	mitochondrial matrix	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005759 mitochondrial matrix	1
CLPP		GO:0035694	mitochondrial protein catabolic process	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0035694 mitochondrial protein catabolic process	1
CLPX		GO:0005759	mitochondrial matrix	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005759 mitochondrial matrix	1
CLPX		GO:0035694	mitochondrial protein catabolic process	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0030163 protein catabolic process	1
CLU		GO:0061684	chaperone-mediated autophagy	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8	GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy	1
CLU		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	already_in_goa_exact	exact	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSPA8	GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy	1
CMYA5		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & FN & SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9		1
CNOT4		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
CNOT4		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	CNOT4;HUWE1;LTN1;MKRN1;MKRN2	GO:0016567 protein ubiquitination	1
CNOT4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
CNPY3		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	ER proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|Folding of TLRs	CNPY3;MZB1	GO:0005515 protein binding	1
COBL		GO:0003779	actin binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|non-enzymatic|actin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|non-enzymatic|actin binding	COBL;COBLL1	GO:0003779 actin binding	1
COBLL1		GO:0003779	actin binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|non-enzymatic|actin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|non-enzymatic|actin binding	COBL;COBLL1	GO:0003779 actin binding	1
COLGALT1		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
COLGALT2		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
COP1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|RFWD|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
COP1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|WD40|other	AHR;ARNT;COP1;DCAF13;DCAF7		1
COPA		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPA		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
COPA		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPB1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPB1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
COPB1		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPB2		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPB2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
COPB2		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPE		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPE		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
COPE		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPG1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPG1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport;GO:0009306 protein secretion	1
COPG1		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPG2		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPG2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport;GO:0009306 protein secretion	1
COPG2		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPS2		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS3		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS4		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS5		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|CSN complex	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|MPN, catalytic subunit;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|CSN complex	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	3
COPS6		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|MPN, noncatalytic subunit	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS7A		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS7B		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS8		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPS9		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|other	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
COPZ1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPZ1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
COPZ1		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
COPZ2		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
COPZ2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
COPZ2		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI vesicle component	COPA;COPB1;COPB2;COPE;COPG1	GO:0030126 COPI vesicle coat	1
CRBN		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|LON, Yippee, DOC	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
CRTAP		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
CRYAA		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	HSPB1;HSPB2;HSPB3;HSPB6;HSPB7		1
CRYAB		GO:0044183	protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml;mitochondrial_proteostasis.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	CRYAB;HSPB1;HSPB2;HSPB3;HSPB6;HSPB7;HSPB8	GO:0006457 protein folding	2
CSE1L		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0005049 nuclear export signal receptor activity;GO:0006611 protein export from nucleus	2
CSE1L		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
CSNK1D		GO:0000045	autophagosome assembly	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|Specific function in sealing of autophagophore membrane unknown	TSG101;VPS28;VPS37A;VPS37B;VPS37C		1
CSNK2B		GO:0032040	small-subunit processome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0005634 nucleus	1
CSNK2B		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	AATF;IMP3;NOP56;UTP4		1
CTBS		GO:0016798	hydrolase activity, acting on glycosyl bonds	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal chitobiase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal chitobiase	CHIT1;CTBS	GO:0016798 hydrolase activity, acting on glycosyl bonds	1
CTSA		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004180 carboxypeptidase activity;GO:0004185 serine-type carboxypeptidase activity	1
CTSA		GO:1904715	negative regulation of chaperone-mediated autophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Negative regulator of CMA by degradation of LAMP2A	AKT1;CTSA;RICTOR	GO:1904715 negative regulation of chaperone-mediated autophagy	1
CTSB		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSC		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0008239 dipeptidyl-peptidase activity	1
CTSD		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSF		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity	1
CTSG		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSH		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSK		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSL		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity	1
CTSO		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity	1
CTSS		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0008233 peptidase activity	1
CTSV		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity	1
CTSW		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity	1
CTSZ		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004180 carboxypeptidase activity;GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0016807 cysteine-type carboxypeptidase activity	1
CUL1		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL2		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL3		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL4A		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL4B		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL5		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|canonical	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL7		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|metazoan	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CUL9		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|Cullin, Armadillo-like;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / Cullin|UBA-like (ARIH1)	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
CUL9		GO:0160072	ubiquitin ligase complex scaffold activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin|metazoan	CUL1;CUL2;CUL3;CUL4A;CUL4B	GO:0160072 ubiquitin ligase complex scaffold activity	1
CWC27		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C		2
CYB5R4		GO:0051879	Hsp90 protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6		1
CYLD		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|CAP Gly-rich domain|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:0061815 Met1-linked polyubiquitin deubiquitinase activity	1
DAD1		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
DAD1		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
DAGLB		GO:0016298	lipase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	ABHD6;DAGLB;LIPA	GO:0016298 lipase activity	1
DARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
DARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
DAXX		GO:0140713	histone chaperone activity	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity	1
DCAF1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|LisH, Armadillo-like	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
DCAF10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
DCAF12L1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF12L2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|WD40|other	AHR;ARNT;COP1;DCAF13;DCAF7	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
DCAF15		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF16		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|transmembrane	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF4L1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF4L2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|IQ motif	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|WD40|other	AHR;ARNT;COP1;DCAF13;DCAF7	GO:0030674 protein-macromolecule adaptor activity	1
DCAF8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF8L1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCAF8L2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DCLRE1A		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA exonuclease|UBZ4-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
DCST1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|acrosome, secretory vescicle	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DDA1		GO:0160072	ubiquitin ligase complex scaffold activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B receptor scaffold	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B receptor scaffold|(no type)|(no subtype)	DDA1		1
DDB1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin adaptor|DDB1	DDB1;SKP1	GO:0030674 protein-macromolecule adaptor activity	1
DDB2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
DDIT3		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|DDIT3 transcriptional program|Transcription factor;PN regulation|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|DDIT3 transcriptional program|Transcription factor;PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	DDIT3;HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	2
DDIT3		GO:0140467	integrated stress response signaling	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Integrated stress response;PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	PN regulation|Transcription factor|Integrated stress response|Transcription of integrated stress response genes	ATF3;ATF4;DDIT3	GO:0140467 integrated stress response signaling	2
DDOST		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
DDOST		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
DDRGK1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
DDRGK1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1;UFM1	GO:0061709 reticulophagy	2
DDRGK1		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
DDX19B		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
DDX19B		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
DDX21		GO:0032040	small-subunit processome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0005730 nucleolus	1
DDX21		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4		1
DDX27		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	BOP1;DDX27;PELP1;PES1;WDR12		1
DDX27		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing	1
DDX28		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
DDX3X		GO:0003743	translation initiation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0006413 translational initiation	1
DDX3X		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
DDX3Y		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
DDX3Y		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
DELE1		GO:0006417	regulation of translation	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|EIF2AK1 modulator	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
DELE1		GO:0140467	integrated stress response signaling	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|EIF2AK1 modulator	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0140467 integrated stress response signaling	1
DENR		GO:0006415	translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|tRNA, mRNA release	ABCE1;EIF2D;ETF1;GSPT1;GSPT2		1
DEPDC5		GO:1990130	GATOR1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	DEPDC5;NPRL2;NPRL3	GO:1990130 GATOR1 complex	1
DEPTOR		GO:0031931	TORC1 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR		1
DEPTOR		GO:0031932	TORC2 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR		1
DERL1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
DERL2		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
DERL3		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
DET1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
DHX15		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex	BOP1;DDX27;PELP1;PES1;WDR12		1
DHX15		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex	AATF;IMP3;NOP56;UTP4		1
DHX16		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|idiosyncratic Ub binding / other	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
DHX29		GO:0003743	translation initiation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0006413 translational initiation	1
DHX29		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
DHX30		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
DIMT1		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000154 rRNA modification	1
DIMT1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000154 rRNA modification;GO:0006364 rRNA processing;GO:0031167 rRNA methylation;GO:0042274 ribosomal small subunit biogenesis	1
DIS3		GO:0006364	rRNA processing	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006364 rRNA processing	1
DIS3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing	1
DKC1		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0031118 rRNA pseudouridine synthesis	1
DKC1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0006364 rRNA processing;GO:0031118 rRNA pseudouridine synthesis	1
DMRTA1		GO:0003677	DNA binding	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|transcription|DNA binding	Ubiquitin Proteasome System|Ubiquitin and UBL binding|transcription|DNA binding|CUE (DMA)	DMRTA1;DMRTA2	GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding	1
DMRTA2		GO:0003677	DNA binding	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|transcription|DNA binding	Ubiquitin Proteasome System|Ubiquitin and UBL binding|transcription|DNA binding|CUE (DMA)	DMRTA1;DMRTA2	GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding	1
DNAAF11		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
DNAAF4		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and CS domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
DNAAF6		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
DNAJA1		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJA2		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJA3		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJA4		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB1		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB1		GO:0061684	chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8		1
DNAJB1		GO:0061738	late endosomal microautophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	DNAJB1;HSPA8;STIP1		1
DNAJB1		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	new_to_goa	exact	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSPA8		1
DNAJB11		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJB12		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB13		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0051087 protein-folding chaperone binding	1
DNAJB14		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB2		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB4		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0051087 protein-folding chaperone binding	1
DNAJB5		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0051087 protein-folding chaperone binding	1
DNAJB6		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB7		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB8		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJB9		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJC1		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0051087 protein-folding chaperone binding	1
DNAJC10		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
DNAJC10		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJC11		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC12		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC13		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC14		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC15		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC16		GO:0030544	Hsp70 protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB		1
DNAJC17		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC18		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJC19		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC2		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJC2		GO:0051083	'de novo' cotranslational protein folding	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning;Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning|RAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning|RAC component	DNAJC2;HSPA14	GO:0051083 'de novo' cotranslational protein folding	2
DNAJC21		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC21		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
DNAJC21		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4		1
DNAJC22		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC24		GO:0030544	Hsp70 protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB		1
DNAJC25		GO:0030544	Hsp70 protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB		1
DNAJC25-GNG10		GO:0030544	Hsp70 protein binding	no_local_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB		1
DNAJC27		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC28		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC3		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0051087 protein-folding chaperone binding	1
DNAJC30		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC4		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC5		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC5B		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
DNAJC5G		GO:0030544	Hsp70 protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB		1
DNAJC6		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0031072 heat shock protein binding	1
DNAJC7		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0031072 heat shock protein binding	1
DNAJC7		GO:0031072	heat shock protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and J domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0031072 heat shock protein binding	1
DNAJC8		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
DNAJC9		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding;GO:0031072 heat shock protein binding;GO:0051087 protein-folding chaperone binding	1
DNASE2		GO:0004518	nuclease activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal nuclease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal nuclease	DNASE2;DNASE2B	GO:0004520 DNA endonuclease activity;GO:0004531 deoxyribonuclease II activity	1
DNASE2B		GO:0004518	nuclease activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal nuclease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal nuclease	DNASE2;DNASE2B	GO:0004520 DNA endonuclease activity;GO:0004531 deoxyribonuclease II activity	1
DNM1L		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Modulator of mitochondrial morphology-induced mitophagy	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901524 regulation of mitophagy	1
DPP4		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	DPP4;DPP7;GGH;LGMN;TPP1	GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity;GO:0008239 dipeptidyl-peptidase activity;GO:0008240 tripeptidyl-peptidase activity	1
DPP7		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	DPP4;DPP7;GGH;LGMN;TPP1	GO:0008233 peptidase activity	1
DRG2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
DTD1		GO:0002161	aminoacyl-tRNA deacylase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA deacylase	Translation|Cytosolic translation|Translation elongation|tRNA deacylase	DTD1;DTD2	GO:0002161 aminoacyl-tRNA deacylase activity	1
DTD2		GO:0002161	aminoacyl-tRNA deacylase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA deacylase	Translation|Cytosolic translation|Translation elongation|tRNA deacylase	DTD1;DTD2	GO:0002161 aminoacyl-tRNA deacylase activity	1
DTL		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:0030674 protein-macromolecule adaptor activity	1
DTX1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|WWE	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DTX2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|WWE	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DTX3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DTX3L		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DTX4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|WWE	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
DUSP12		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
DUSP12		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4		1
DZIP3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|TTC3/DZIP3;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|UBA-like (other)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
E2F1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|E2F1 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|E2F1 transcriptional program|Transcription factor	E2F1	GO:0003700 DNA-binding transcription factor activity	1
E4F1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|C2H2 ZnF (two clusters)	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
EARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
ECPAS		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator|Armadillo-like	ECPAS;PITHD1;PSME4;PSMF1	GO:0070628 proteasome binding	1
ECT2L		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
EDEM1		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1		1
EDEM1		GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	EDEM1;EDEM2;EDEM3;MAN1B1	GO:1904382 mannose trimming involved in glycoprotein ERAD pathway	1
EDEM2		GO:0006487	protein N-linked glycosylation	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0009100 glycoprotein metabolic process	1
EDEM2		GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	EDEM1;EDEM2;EDEM3;MAN1B1	GO:0009100 glycoprotein metabolic process;GO:0036503 ERAD pathway;GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway	1
EDEM3		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1		1
EDEM3		GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	EDEM1;EDEM2;EDEM3;MAN1B1	GO:1904382 mannose trimming involved in glycoprotein ERAD pathway	1
EDF1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
EEA1		GO:0005543	phospholipid binding	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|trafficking|phospholipid binding	Ubiquitin Proteasome System|Ubiquitin and UBL binding|trafficking|phospholipid binding|UBZ (C2H2)	EEA1	GO:0005545 1-phosphatidylinositol binding	1
EEF1A1		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EEF1A1		GO:1904716	positive regulation of chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of LAMP2A multimerization	AMBRA1;GFAP;MT-RNR2;PSME1;TP53	GO:1904714 regulation of chaperone-mediated autophagy	1
EEF1A2		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EEF1A2		GO:1904716	positive regulation of chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of LAMP2A multimerization	AMBRA1;GFAP;MT-RNR2;PSME1;TP53	GO:1904714 regulation of chaperone-mediated autophagy	1
EEF1B2		GO:0005853	eukaryotic translation elongation factor 1 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|EEF1B complex	Translation|Cytosolic translation|Translation elongation|EEF1B complex	EEF1B2;EEF1D;EEF1G	GO:0005853 eukaryotic translation elongation factor 1 complex	1
EEF1D		GO:0005853	eukaryotic translation elongation factor 1 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|EEF1B complex	Translation|Cytosolic translation|Translation elongation|EEF1B complex	EEF1B2;EEF1D;EEF1G	GO:0005853 eukaryotic translation elongation factor 1 complex	1
EEF1E1		GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|multisynthase complex	Translation|Cytosolic translation|Translation elongation|multisynthase complex	AIMP1;AIMP2;EEF1E1	GO:0017101 aminoacyl-tRNA synthetase multienzyme complex	1
EEF1G		GO:0005853	eukaryotic translation elongation factor 1 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|EEF1B complex	Translation|Cytosolic translation|Translation elongation|EEF1B complex	EEF1B2;EEF1D;EEF1G	GO:0005737 cytoplasm	1
EEF2		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EEF2K		GO:0003746	translation elongation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0006414 translational elongation	1
EEF2KMT		GO:0003746	translation elongation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT		1
EEFSEC		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EFL1		GO:0030687	preribosome, large subunit precursor	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:1990904 ribonucleoprotein complex	1
EFL1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042256 cytosolic ribosome assembly	1
EIF1		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF1		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF1AX		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF1AX		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF1AY		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF1AY		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2A		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF2A		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2AK1		GO:0006417	regulation of translation	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0006417 regulation of translation	1
EIF2AK1		GO:0032055	negative regulation of translation in response to stress	more_specific_than_existing_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4	GO:0006417 regulation of translation;GO:0006950 response to stress	1
EIF2AK1		GO:0140467	integrated stress response signaling	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0140467 integrated stress response signaling	1
EIF2AK2		GO:0006417	regulation of translation	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0006446 regulation of translational initiation;GO:0017148 negative regulation of translation;GO:2000766 negative regulation of cytoplasmic translation	1
EIF2AK2		GO:0032055	negative regulation of translation in response to stress	more_specific_than_existing_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4	GO:0017148 negative regulation of translation	1
EIF2AK2		GO:0140467	integrated stress response signaling	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
EIF2AK3		GO:0006417	regulation of translation	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1;PN regulation|Translation regulator|Unfolded protein response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0006446 regulation of translational initiation;GO:0017148 negative regulation of translation;GO:0032055 negative regulation of translation in response to stress;GO:0032057 negative regulation of translational initiation in response to stress;GO:0036491 regulation of translation initiation in response to endoplasmic reticulum stress;GO:0045182 translation regulator activity;GO:0045947 negative regulation of translational initiation	2
EIF2AK3		GO:0032055	negative regulation of translation in response to stress	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4	GO:0032055 negative regulation of translation in response to stress	1
EIF2AK3		GO:0140467	integrated stress response signaling	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0036499 PERK-mediated unfolded protein response	1
EIF2AK3		GO:1903894	regulation of IRE1-mediated unfolded protein response	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Unfolded protein response;PN regulation|Translation regulator|Unfolded protein response|Phosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Unfolded protein response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK3		2
EIF2AK4		GO:0006417	regulation of translation	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0006446 regulation of translational initiation;GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation;GO:0032057 negative regulation of translational initiation in response to stress;GO:0045947 negative regulation of translational initiation;GO:0071264 positive regulation of translational initiation in response to starvation	1
EIF2AK4		GO:0032055	negative regulation of translation in response to stress	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4		1
EIF2AK4		GO:0140467	integrated stress response signaling	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Phosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0140469 GCN2-mediated signaling	1
EIF2B1		GO:0005851	eukaryotic translation initiation factor 2B complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2B complex	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5	GO:0005851 eukaryotic translation initiation factor 2B complex	1
EIF2B1		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2B2		GO:0005851	eukaryotic translation initiation factor 2B complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2B complex	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5	GO:0005851 eukaryotic translation initiation factor 2B complex	1
EIF2B2		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2B3		GO:0005851	eukaryotic translation initiation factor 2B complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2B complex	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5	GO:0005851 eukaryotic translation initiation factor 2B complex	1
EIF2B3		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2B4		GO:0005851	eukaryotic translation initiation factor 2B complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2B complex	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5	GO:0005851 eukaryotic translation initiation factor 2B complex	1
EIF2B4		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2B5		GO:0005851	eukaryotic translation initiation factor 2B complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2B complex	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2B2;EIF2B3;EIF2B4;EIF2B5	GO:0005851 eukaryotic translation initiation factor 2B complex	1
EIF2B5		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2B complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2D		GO:0006415	translational termination	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|tRNA, mRNA release	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0043933 protein-containing complex organization	1
EIF2S1		GO:0005850	eukaryotic translation initiation factor 2 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2 complex	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0005850 eukaryotic translation initiation factor 2 complex	1
EIF2S1		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2S2		GO:0005850	eukaryotic translation initiation factor 2 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2 complex	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0005850 eukaryotic translation initiation factor 2 complex	1
EIF2S2		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2S3		GO:0005850	eukaryotic translation initiation factor 2 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2 complex	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0005850 eukaryotic translation initiation factor 2 complex	1
EIF2S3		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF2S3B		GO:0005850	eukaryotic translation initiation factor 2 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF2 complex	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0005850 eukaryotic translation initiation factor 2 complex	1
EIF2S3B		GO:0006413	translational initiation	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF2 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0001731 formation of translation preinitiation complex;GO:0003743 translation initiation factor activity	1
EIF3A		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3A		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3B		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3B		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3C		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3C		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3CL		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3CL		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3D		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3D		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3E		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3E		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3F		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml;ubiquitin_proteasome_system.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|EIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|EIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D;EIF3F;EIF3H	GO:0005852 eukaryotic translation initiation factor 3 complex	2
EIF3F		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3G		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3G		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3H		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml;ubiquitin_proteasome_system.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|EIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|EIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D;EIF3F;EIF3H	GO:0005852 eukaryotic translation initiation factor 3 complex	2
EIF3H		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3I		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3I		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3J		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3J		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3J		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
EIF3K		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3K		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3L		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3L		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF3M		GO:0005852	eukaryotic translation initiation factor 3 complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF3 complex	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF3A;EIF3B;EIF3C;EIF3CL;EIF3D	GO:0005852 eukaryotic translation initiation factor 3 complex	1
EIF3M		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF3 complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4A1		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4A1		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4A2		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4A2		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4B		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF4B		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4E		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4E		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4E2		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4E2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
EIF4E2		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4E3		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4E3		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4EBP1		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
EIF4EBP1		GO:0006413	translational initiation	supported_by_goa_regulation	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0045947 negative regulation of translational initiation	1
EIF4EBP2		GO:0003743	translation initiation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0006412 translation	1
EIF4EBP2		GO:0006413	translational initiation	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006412 translation	1
EIF4EBP3		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
EIF4EBP3		GO:0006413	translational initiation	supported_by_goa_regulation	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0045947 negative regulation of translational initiation	1
EIF4G1		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4G1		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4G2		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4G2		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4G3		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF4G3		GO:0016281	eukaryotic translation initiation factor 4F complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|eIF4F complex	Translation|Cytosolic translation|Translation initiation|eIF4F complex	EIF4A1;EIF4A2;EIF4E;EIF4E2;EIF4E3	GO:0016281 eukaryotic translation initiation factor 4F complex	1
EIF4H		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF4H		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF5		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF5		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF5A		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EIF5A		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
EIF5A2		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EIF5AL1		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT	GO:0003746 translation elongation factor activity	1
EIF5B		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0003743 translation initiation factor activity	1
EIF5B		GO:0006413	translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006413 translational initiation	1
EIF5B		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
EIF5B		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0042255 ribosome assembly	1
EIF6		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
EIF6		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0000054 ribosomal subunit export from nucleus;GO:0000460 maturation of 5.8S rRNA;GO:0000470 maturation of LSU-rRNA;GO:0042256 cytosolic ribosome assembly;GO:0042273 ribosomal large subunit biogenesis;GO:1902626 assembly of large subunit precursor of preribosome	1
ELAC2		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|pre-rRNA processing nuclease|RNAse Z	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
ELOA		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
EMC1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC1		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC1		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC10		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC10		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC10		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC2		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC2		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC2		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC3		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC3		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC4		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC4		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC4		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC6		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC6		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC6		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC7		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC7		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC7		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC8		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC8		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC8		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMC9		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
EMC9		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
EMC9		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
EMG1		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0070475 rRNA base methylation	1
EMG1		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
EMG1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex;Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis;GO:0070475 rRNA base methylation	2
ENC1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
ENGASE		GO:0006517	protein deglycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ENGASE;MAN2C1;NGLY1		1
ENGASE		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
EPRS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
ERAL1		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA chaperone	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0180026 mitochondrial small ribosomal subunit assembly	1
ERCC5		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA endonuclease|UBM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0000724 double-strand break repair via homologous recombination;GO:0006283 transcription-coupled nucleotide-excision repair;GO:0006285 base-excision repair, AP site formation;GO:0006289 nucleotide-excision repair	1
ERCC6		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA helicase|idiosyncratic Ub binding / other	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
ERCC6L		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA helicase|SIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
ERCC8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
ERI1		GO:0006364	rRNA processing	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006364 rRNA processing	1
ERI1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0000460 maturation of 5.8S rRNA;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0031125 rRNA 3'-end processing	1
ERLEC1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
ERLIN1		GO:0000151	ubiquitin ligase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|RNF170 / ERLIN complex|noncatalytic / BAND 7	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0032991 protein-containing complex	1
ERLIN1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	DERL1;DERL2;DERL3;ERLIN1;ERLIN2;HERPUD1;JKAMP;SVIP;SYVN1;TMUB1	GO:0036503 ERAD pathway	2
ERLIN2		GO:0000151	ubiquitin ligase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|RNF170 / ERLIN complex|noncatalytic / BAND 7	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0032991 protein-containing complex	1
ERLIN2		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	DERL1;DERL2;DERL3;ERLIN1;ERLIN2;HERPUD1;JKAMP;SVIP;SYVN1;TMUB1	GO:0036503 ERAD pathway	2
ERN1		GO:0030968	endoplasmic reticulum unfolded protein response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor regulator|Unfolded protein response	PN regulation|Transcription factor regulator|Unfolded protein response|XBP1 modulator	ERN1	GO:0030968 endoplasmic reticulum unfolded protein response	1
ERN1		GO:1903894	regulation of IRE1-mediated unfolded protein response	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor regulator|Unfolded protein response|XBP1 modulator	PN regulation|Transcription factor regulator|Unfolded protein response|XBP1 modulator	ERN1		1
ERO1A		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases;ER proteostasis|Folding enzyme|Protein disulfide isomerases|Protein disulfide isomerase reoxidation	ER proteostasis|Folding enzyme|Protein disulfide isomerases|Protein disulfide isomerase reoxidation	AGR2;AGR3;CASQ1;CASQ2;DNAJC10;ERO1A;ERO1B		2
ERO1B		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases;ER proteostasis|Folding enzyme|Protein disulfide isomerases|Protein disulfide isomerase reoxidation	ER proteostasis|Folding enzyme|Protein disulfide isomerases|Protein disulfide isomerase reoxidation	AGR2;AGR3;CASQ1;CASQ2;DNAJC10;ERO1A;ERO1B		2
ERP27		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
ERP29		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
ERP44		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
ETF1		GO:0006415	translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Stop codon recognition	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0006415 translational termination	1
ETF1		GO:0016149	translation release factor activity, codon specific	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination|Stop codon recognition	Translation|Cytosolic translation|Translation termination|Stop codon recognition	ETF1	GO:0016149 translation release factor activity, codon specific	1
EXOSC10		GO:0006364	rRNA processing	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006364 rRNA processing	1
EXOSC10		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0000460 maturation of 5.8S rRNA;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis	1
FAAP20		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA repair accessory|UBZ2-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0036297 interstrand cross-link repair	1
FAF2		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|mitoTAD pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
FAF2		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
FAM72A		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FAM8A1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
FAN1		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA exonuclease|UBZ4-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
FANCA		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCB		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCC		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCD2		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|binding to damaged DNA|idiosyncratic Ub binding / alpha solenoid	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
FANCE		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCF		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCG		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|noncatalytic / TPR	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
FANCL		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|FANC core complex|catalytic / RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component|FANC / catalytic subunit|idiosyncratic Ub binding / ELF	ANAPC11;ANAPC2;FANCL;GID8;KCMF1;MAEA;RANBP10;RMND5A;RMND5B;SHARPIN		2
FARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
FARSA		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
FARSB		GO:0004812	aminoacyl-tRNA ligase activity	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004826 phenylalanine-tRNA ligase activity	1
FASTKD2		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
FAU		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
FAU		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
FBH1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|DNA helicase	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBL		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
FBL		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0000451 rRNA 2'-O-methylation;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0031167 rRNA methylation;GO:0042274 ribosomal small subunit biogenesis	1
FBXL12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL14		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL15		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL16		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL18		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL19		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR with PHD	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXL2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXL20		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL21P		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL22		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXL5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXL8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|CASH	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|CASH, UBR-type ZnF	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO15		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO16		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|FBA	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|FBA	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO21		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO22		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO24		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|RCC1	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO25		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO27		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|FBA	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO28		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO30		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|TRAF-type ZnF	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO31		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO32		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO33		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO34		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO36		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO38		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO39		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|DNA helicase	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO40		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|TRAF-type ZnF	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO41		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO42		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|KELCH	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO43		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|ZBR-type ZnF	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO44		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|FBA	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO45		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|SPRY	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO46		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO47		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO48		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXO5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|ZBR-type ZnF	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|FBA	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO7		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Mitophagy|PINK/PRKN pathway	FBXO7;VPS13D	GO:0000422 autophagy of mitochondrion	1
FBXO7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|CUL1 receptor / F-box	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|PI31, UBL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|CUL1 receptor / F-box	FBXL2;FBXL3;FBXL4;FBXL5;FBXO7;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	2
FBXO8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXO9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|other	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXW10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXW10B		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:0003674 molecular_function	1
FBXW11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXW12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXW2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXW4		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|CUL1 receptor|idiosyncratic Ub binding / WD40	ASB2;FBXW4;FBXW7;FBXW8;PML		1
FBXW4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXW5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FBXW7		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|CUL1 receptor|idiosyncratic Ub binding / WD40	ASB2;FBXW4;FBXW7;FBXW8;PML		1
FBXW7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FBXW8		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|CUL1 receptor|idiosyncratic Ub binding / WD40	ASB2;FBXW4;FBXW7;FBXW8;PML		1
FBXW8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul7 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul7 substrate receptor|F-box, noncanonical contact|WD40	FBXL2;FBXL3;FBXL4;FBXL5;FBXW8;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	2
FBXW9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|WD40	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
FCF1		GO:0006364	rRNA processing	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0030490 maturation of SSU-rRNA	1
FCF1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
FEM1A		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|ankyrin repeat	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FEM1B		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|ankyrin repeat	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FEM1C		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|ankyrin repeat	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
FKBP10		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP11		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP14		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP15		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP1A		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP1B		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP2		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP3		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP4		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP4		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and PPIase domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding;GO:0031072 heat shock protein binding	1
FKBP5		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP5		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and PPIase domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding;GO:0031072 heat shock protein binding	1
FKBP6		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3		2
FKBP6		GO:0031072	heat shock protein binding	entailed_by_goa_closure	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and PPIase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0051879 Hsp90 protein binding	1
FKBP7		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP8		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:1901524 regulation of mitophagy	1
FKBP8		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	AIP;AIPL1;FKBP1A;FKBP1B;FKBP3	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBP8		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and PPIase domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
FKBP9		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|FKBP type	CAMLG;FKBP10;FKBP11;FKBP2;FKBP7;FKBP9;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
FKBPL		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and PPIase domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
FNIP1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
FNIP2		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
FOS		GO:0035976	transcription factor AP-1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	FOS;FOSB;FOSL1;FOSL2;JUN	GO:0035976 transcription factor AP-1 complex	1
FOSB		GO:0035976	transcription factor AP-1 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	FOS;FOSB;FOSL1;FOSL2;JUN	GO:0005634 nucleus	1
FOSL1		GO:0035976	transcription factor AP-1 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	FOS;FOSB;FOSL1;FOSL2;JUN	GO:0005634 nucleus	1
FOSL2		GO:0035976	transcription factor AP-1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	FOS;FOSB;FOSL1;FOSL2;JUN	GO:0035976 transcription factor AP-1 complex	1
FOXO1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|FOXO transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|FOXO transcriptional program|Transcription factor	FOXO1;FOXO3	GO:0003700 DNA-binding transcription factor activity	1
FOXO3		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|FOXO transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|FOXO transcriptional program|Transcription factor	FOXO1;FOXO3	GO:0003700 DNA-binding transcription factor activity	1
FUCA1		GO:0015928	fucosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal fusocidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal fusocidase	FUCA1;FUCA2	GO:0004560 alpha-L-fucosidase activity	1
FUCA2		GO:0015928	fucosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal fusocidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal fusocidase	FUCA1;FUCA2	GO:0004560 alpha-L-fucosidase activity	1
FUNDC1		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0000423 mitophagy	1
FYCO1		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|Miscellaneous function - movement of autophagosomes along microtubules	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3		2
FZR1		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0005680 anaphase-promoting complex	1
FZR1		GO:0005680	anaphase-promoting complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|Anaphase Promoting Complex|substrate adaptor / WD40	ANAPC1;ANAPC10;ANAPC11;ANAPC2;CDC16	GO:0005680 anaphase-promoting complex	1
G2E3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|PHD;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|other	ITCH;NEDD4;NEDD4L;PRPF19;SMURF1;SMURF2;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	2
GAA		GO:0090599	alpha-glucosidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal glucosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal glucosidase	GAA	GO:0090599 alpha-glucosidase activity	1
GABARAP		GO:0061739	protein lipidation involved in autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3B	GO:0000045 autophagosome assembly	1
GABARAP		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
GABARAPL1		GO:0061739	protein lipidation involved in autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3B	GO:0000045 autophagosome assembly	1
GABARAPL1		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
GABARAPL2		GO:0000045	autophagosome assembly	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|Specific function in sealing of autophagophore membrane unknown	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000045 autophagosome assembly	1
GABARAPL2		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
GADD45GIP1		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
GADD45GIP1		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
GAK		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
GALNS		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
GAN		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
GANAB		GO:0006487	protein N-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Glucose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006491 N-glycan processing	1
GAR1		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000454 snoRNA guided rRNA pseudouridine synthesis	1
GAR1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
GARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase;Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase;Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS1;AARS2;CARS1;CARS2;DARS1;DARS2;EARS2;EPRS1;FARS2;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	2
GATA1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|GATA1 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|GATA1 transcriptional program|Transcription factor	GATA1	GO:0003700 DNA-binding transcription factor activity	1
GATA4		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|GATA4 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|GATA4 transcriptional program|Transcription factor	GATA4	GO:0003700 DNA-binding transcription factor activity	1
GATB		GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex;Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	GATB;GATC;QRSL1	GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex	2
GATC		GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex;Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	GATB;GATC;QRSL1	GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex	2
GBF1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
GBF1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
GBF1		GO:0030126	COPI vesicle coat	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI coating and uncoating	ARF1;GBF1	GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0016020 membrane	1
GCN1		GO:0006417	regulation of translation	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|EIF2AK4 modulator	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0006417 regulation of translation	1
GCN1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes;Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		2
GCN1		GO:0016567	protein ubiquitination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GCN1;RNF14;RNF25		1
GCN1		GO:0140467	integrated stress response signaling	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|EIF2AK4 modulator	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0140469 GCN2-mediated signaling	1
GCNA		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA protein crosslink recognition|SIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0106300 protein-DNA covalent cross-linking repair	1
GET1		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0090150 establishment of protein localization to membrane	1
GET1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
GET3		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA		1
GET3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
GET4		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane	1
GET4		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
GFAP		GO:1904716	positive regulation of chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of LAMP2A multimerization	AMBRA1;GFAP;MT-RNR2;PSME1;TP53	GO:1904714 regulation of chaperone-mediated autophagy	1
GFER		GO:0160203	mitochondrial disulfide relay system	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Folding enzyme|Protein disulfide isomerases	Mitochondrial proteostasis|Folding enzyme|Protein disulfide isomerases	CHCHD4;GFER	GO:0160203 mitochondrial disulfide relay system	1
GFM1		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	GFM1;GUF1;TSFM;TUFM	GO:0003746 translation elongation factor activity	1
GGH		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	DPP4;DPP7;GGH;LGMN;TPP1	GO:0008238 exopeptidase activity;GO:0008242 omega peptidase activity;GO:0034722 gamma-glutamyl-peptidase activity	1
GID4		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
GID8		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / CRA, LisH	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
GIGYF1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
GIGYF2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
GLA		GO:0015925	galactosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal galactosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal galactosidase	GLA;GLB1	GO:0004557 alpha-galactosidase activity	1
GLB1		GO:0015925	galactosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal galactosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal galactosidase	GLA;GLB1	GO:0004565 beta-galactosidase activity	1
GLE1		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
GLE1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
GLMN		GO:1904667	negative regulation of ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|CRL inhibitor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|CRL regulator|CRL inhibitor	GLMN		1
GMCL1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|GCL	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
GMCL2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|GCL	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
GNL2		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
GNL2		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4		1
GNS		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
GORAB		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	COPA;COPB1;COPB2;COPE;COPG1		1
GORAB		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
GORAB		GO:0030126	COPI vesicle coat	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	GORAB;SCYL1;SCYL3	GO:0005737 cytoplasm;GO:0005794 Golgi apparatus	1
GPLD1		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004621 GPI anchor phospholipase D activity;GO:0004630 D-type glycerophospholipase activity	1
GPS1		GO:0008180	COP9 signalosome	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex;Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|CSN complex|deNEDDylase|PCI	COPS2;COPS3;COPS4;COPS5;COPS6	GO:0008180 COP9 signalosome	2
GRAMD1A		GO:0120020	cholesterol transfer activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulates cholesterol transfer to autophagophore	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulates cholesterol transfer to autophagophore	GRAMD1A	GO:0120020 cholesterol transfer activity	1
GRN		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Miscellaneous function - lysosomal acidification	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
GRPEL1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
GRPEL1		GO:0001405	PAM complex, Tim23 associated import motor	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	GRPEL1;GRPEL2	GO:0001405 PAM complex, Tim23 associated import motor	1
GRPEL2		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
GRPEL2		GO:0001405	PAM complex, Tim23 associated import motor	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|GRPE subtype	GRPEL1;GRPEL2	GO:0001405 PAM complex, Tim23 associated import motor	1
GSPT1		GO:0003747	translation release factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination|Polypeptide release	Translation|Cytosolic translation|Translation termination|Polypeptide release	GSPT1;GSPT2	GO:0003747 translation release factor activity	1
GSPT1		GO:0006415	translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Polypeptide release	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0006415 translational termination	1
GSPT2		GO:0003747	translation release factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination|Polypeptide release	Translation|Cytosolic translation|Translation termination|Polypeptide release	GSPT1;GSPT2	GO:0003747 translation release factor activity	1
GSPT2		GO:0006415	translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Polypeptide release	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0006415 translational termination	1
GTPBP1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
GTPBP1		GO:0072344	rescue of stalled cytosolic ribosome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0002181 cytoplasmic translation;GO:0006414 translational elongation	1
GTPBP10		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	GTPBP10;GTPBP6;METTL15;MTERF4;MTG1;MTG2;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	2
GTPBP2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
GTPBP2		GO:0072344	rescue of stalled cytosolic ribosome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0006414 translational elongation	1
GTPBP4		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
GTPBP4		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
GTPBP6		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	GTPBP10;GTPBP6;METTL15;MTERF4;MTG1;MTG2;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	2
GTPBP6		GO:0070126	mitochondrial translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR		1
GTPBP6		GO:7770016	rescue of stalled mitochondrial ribosome	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	GTPBP6;MRPL58;MTRES1;MTRFR		1
GUF1		GO:0003746	translation elongation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	GFM1;GUF1;TSFM;TUFM	GO:0006412 translation	1
GUSB		GO:0046574	glucuronidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal glucuronidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal glucuronidase	GUSB	GO:0004566 beta-glucuronidase activity	1
HACD3		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
HACE1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|ankyrin repeats	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HAP1		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Retrograde transport along axons	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Retrograde transport along axons	ARL8A;ARL8B;HAP1;HTT;MAP1LC3B;RILP;RUFY3		2
HAPSTR1		GO:0006950	response to stress	supported_by_goa_regulation	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Stress response integration	PN regulation|Stress response integration|Multi-stress response|Modulation of stress responses	HAPSTR1;HAPSTR2;HUWE1	GO:0080135 regulation of cellular response to stress	1
HAPSTR2		GO:0006950	response to stress	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Stress response integration	PN regulation|Stress response integration|Multi-stress response|Modulation of stress responses	HAPSTR1;HAPSTR2;HUWE1		1
HARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
HARS2		GO:0004812	aminoacyl-tRNA ligase activity	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004821 histidine-tRNA ligase activity	1
HAT1		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
HBS1L		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
HBS1L		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
HEATR1		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
HEATR1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
HEATR3		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	HEATR3;HIKESHI;KPNA2;KPNB1;SNUPN;XPO1	GO:0006606 protein import into nucleus	2
HEATR3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
HEATR3		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
HEATR3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042273 ribosomal large subunit biogenesis	1
HECTD1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|Armadillo-like, ankyrin repeats	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HECTD2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|other	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HECTD3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|DOC	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HECTD4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|transmembrane, SPRY	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HECW1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HECW2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERC1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|WD40, SPRY	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERC2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|DOC;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|HECT / HERC-type / RCC1|ZZ Zinc finger (SUMO binding), UBA	ASB2;FBXW4;FBXW7;FBXW8;ITCH;NEDD4;NEDD4L;PML;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	2
HERC3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|other	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERC4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|other	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERC5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|other	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERC6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|HERC-type / RCC1|other	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
HERPUD1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
HERPUD2		GO:0036503	ERAD pathway	new_to_goa	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1		1
HGSNAT		GO:0015019	heparan-alpha-glucosaminide N-acetyltransferase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparin acetyltransferase to prepare for heparin degradation	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparin acetyltransferase to prepare for heparin degradation	HGSNAT	GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity	1
HIF1A		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|HIF1A transcriptional program|Transcription factor;PN regulation|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|HIF1A transcriptional program|Transcription factor;PN regulation|Transcription factor|Hypoxic stress response|Transcription of hypoxic stress response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	2
HIF1A		GO:0071456	cellular response to hypoxia	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Hypoxic stress response;PN regulation|Transcription factor|Hypoxic stress response|Transcription of hypoxic stress response genes	PN regulation|Transcription factor|Hypoxic stress response|Transcription of hypoxic stress response genes	HIF1A	GO:0071456 cellular response to hypoxia	2
HIKESHI		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	HEATR3;HIKESHI;KPNA2;KPNB1;SNUPN;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
HIKESHI		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0015031 protein transport	1
HIRA		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
HJURP		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
HK2		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1905091 positive regulation of type 2 mitophagy	1
HLTF		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|helicase	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
HOXB4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
HPSE		GO:0016798	hydrolase activity, acting on glycosyl bonds	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparinase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparinase	HPSE;NAGLU	GO:0016798 hydrolase activity, acting on glycosyl bonds	1
HSCB		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Mitochondrial proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0003674 molecular_function;GO:0005515 protein binding;GO:0051087 protein-folding chaperone binding	1
HSD17B10		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|pre-rRNA processing nuclease|Subunit of RNAse P complex	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
HSF1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
HSF1		GO:0034605	cellular response to heat	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Heat shock response;PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HSF1;HSF2;HSF4;HSF5	GO:0034605 cellular response to heat	2
HSF2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
HSF2		GO:0034605	cellular response to heat	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Heat shock response;PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HSF1;HSF2;HSF4;HSF5		2
HSF4		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
HSF4		GO:0034605	cellular response to heat	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Heat shock response;PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HSF1;HSF2;HSF4;HSF5		2
HSF5		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
HSF5		GO:0034605	cellular response to heat	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Heat shock response;PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	PN regulation|Transcription factor|Heat shock response|Transcription of heat shock response genes	HSF1;HSF2;HSF4;HSF5		2
HSP90AA1		GO:0061684	chaperone-mediated autophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8	GO:0061684 chaperone-mediated autophagy	1
HSP90AA1		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	HSP90AA1;HSP90AB1;ST13;STIP1;STUB1	GO:0061684 chaperone-mediated autophagy	1
HSP90AA1		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90	HSP90AA1;HSP90AB1	GO:0140662 ATP-dependent protein folding chaperone	1
HSP90AB1		GO:0061684	chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8		1
HSP90AB1		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	HSP90AA1;HSP90AB1;ST13;STIP1;STUB1		1
HSP90AB1		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90	HSP90AA1;HSP90AB1	GO:0140662 ATP-dependent protein folding chaperone	1
HSP90B1		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP90 system|HSP90	ER proteostasis|Chaperone|HSP90 system|HSP90	HSP90B1	GO:0140662 ATP-dependent protein folding chaperone	1
HSPA13		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|HSP70	ER proteostasis|Chaperone|HSP70 system|HSP70	HSPA13;HSPA5	GO:0044183 protein folding chaperone	1
HSPA14		GO:0051083	'de novo' cotranslational protein folding	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning;Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning|RAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide chaperoning|RAC component	DNAJC2;HSPA14	GO:0051083 'de novo' cotranslational protein folding	2
HSPA14		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0006457 protein folding;GO:0044183 protein folding chaperone	1
HSPA1A		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0044183 protein folding chaperone	1
HSPA1B		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0044183 protein folding chaperone	1
HSPA1L		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0044183 protein folding chaperone	1
HSPA2		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0044183 protein folding chaperone	1
HSPA4		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSP110/GRP170 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
HSPA4L		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSP110/GRP170 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
HSPA5		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|HSP70	ER proteostasis|Chaperone|HSP70 system|HSP70	HSPA13;HSPA5	GO:0044183 protein folding chaperone	1
HSPA6		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0044183 protein folding chaperone	1
HSPA8		GO:0035973	aggrephagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	BAG3;HSPA8;HSPB8;STUB1		1
HSPA8		GO:0061684	chaperone-mediated autophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8	GO:0061684 chaperone-mediated autophagy	1
HSPA8		GO:0061738	late endosomal microautophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	DNAJB1;HSPA8;STIP1		1
HSPA8		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	already_in_goa_exact	exact	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate delivery	CLU;DNAJB1;HSPA8	GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy	1
HSPA8		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70	HSPA1A;HSPA1B;HSPA1L;HSPA2;HSPA6	GO:0140662 ATP-dependent protein folding chaperone	1
HSPA9		GO:0140662	ATP-dependent protein folding chaperone	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70	Mitochondrial proteostasis|Chaperone|HSP70 system|HSP70	HSPA9	GO:0006457 protein folding;GO:0044183 protein folding chaperone	1
HSPB1		GO:0044183	protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml;mitochondrial_proteostasis.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	CRYAB;HSPB1;HSPB2;HSPB3;HSPB6;HSPB7;HSPB8	GO:0044183 protein folding chaperone	2
HSPB2		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml;mitochondrial_proteostasis.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	CRYAB;HSPB1;HSPB2;HSPB3;HSPB6;HSPB7;HSPB8		2
HSPB3		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml;mitochondrial_proteostasis.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	CRYAB;HSPB1;HSPB2;HSPB3;HSPB6;HSPB7;HSPB8		2
HSPB6		GO:0044183	protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	HSPB1;HSPB2;HSPB3;HSPB6;HSPB7	GO:0044183 protein folding chaperone	1
HSPB7		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	HSPB1;HSPB2;HSPB3;HSPB6;HSPB7		1
HSPB8		GO:0035973	aggrephagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	BAG3;HSPA8;HSPB8;STUB1	GO:1905337 positive regulation of aggrephagy	1
HSPB8		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml;mitochondrial_proteostasis.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP;Mitochondrial proteostasis|Chaperone|small HSP	CRYAB;HSPB1;HSPB2;HSPB3;HSPB6;HSPB7;HSPB8		2
HSPB9		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	HSPB1;HSPB2;HSPB3;HSPB6;HSPB7		1
HSPBP1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSPBP1 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
HSPD1		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP60	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP60	HSPD1	GO:0140662 ATP-dependent protein folding chaperone	1
HSPE1		GO:0044183	protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP10	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP10	HSPE1;HSPE1-MOB4	GO:0044183 protein folding chaperone	1
HSPE1-MOB4		GO:0044183	protein folding chaperone	no_local_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP10	Mitochondrial proteostasis|Chaperone|HSP60 system|HSP10	HSPE1;HSPE1-MOB4		1
HSPH1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSP110/GRP170 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
HTRA2		GO:0005758	mitochondrial intermembrane space	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ATP23;HTRA2;NLN	GO:0005758 mitochondrial intermembrane space	1
HTRA2		GO:0035694	mitochondrial protein catabolic process	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0035694 mitochondrial protein catabolic process	1
HTT		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Retrograde transport along axons	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Retrograde transport along axons	ARL8A;ARL8B;HAP1;HTT;MAP1LC3B;RILP;RUFY3		2
HUWE1		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Direct recruitment of AMBRA1	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1905091 positive regulation of type 2 mitophagy	1
HUWE1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
HUWE1		GO:0006950	response to stress	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Stress response integration	PN regulation|Stress response integration|Multi-stress response|HAPSTR1 modulator	HAPSTR1;HAPSTR2;HUWE1	GO:0006284 base-excision repair	1
HUWE1		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	CNOT4;HUWE1;LTN1;MKRN1;MKRN2	GO:0016567 protein ubiquitination	1
HUWE1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|Armadillo-like, WWE, UBA;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|HECT / Armadillo-like, WW|UIM, UBM, UBA	ASB2;FBXW4;FBXW7;FBXW8;ITCH;NEDD4;NEDD4L;PML;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	2
HYAL1		GO:0004415	hyalurononglucosaminidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	HYAL1;HYAL2;HYAL3	GO:0004415 hyalurononglucosaminidase activity	1
HYAL2		GO:0004415	hyalurononglucosaminidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	HYAL1;HYAL2;HYAL3	GO:0004415 hyalurononglucosaminidase activity	1
HYAL3		GO:0004415	hyalurononglucosaminidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal hyaluronidase	HYAL1;HYAL2;HYAL3	GO:0004415 hyalurononglucosaminidase activity	1
HYOU1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	ER proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSP110/GRP170 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
HYPK		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|Modulator of NatA and NatE complexes	NAA10;NAA15;NAA20;NAA25;NAA30		1
IARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
IARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
IBTK		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|ankyrin, RCC1	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
IDE		GO:0004222	metalloendopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	extracellular_proteostasis.yaml	Extracellular proteostasis|Protease|Extracellular and intracellular	Extracellular proteostasis|Protease|Extracellular and intracellular	IDE	GO:0004222 metalloendopeptidase activity	1
IDE		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	extracellular_proteostasis.yaml	Extracellular proteostasis|Protease	Extracellular proteostasis|Protease|Extracellular and intracellular	IDE;MME	GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity	1
IDS		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
IDUA		GO:0003940	L-iduronidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal iduronidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal iduronidase	IDUA	GO:0003940 L-iduronidase activity	1
IFI27		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|SKP2 specific|transmembrane	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2	GO:0060090 molecular adaptor activity	1
IFI30		GO:0015035	protein-disulfide reductase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal thiol reductase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal thiol reductase	IFI30	GO:0016667 oxidoreductase activity, acting on a sulfur group of donors	1
IKBKB		GO:0008385	IkappaB kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	CHUK;IKBKB;IKBKG;MAP3K7	GO:0008385 IkappaB kinase complex	1
IKBKG		GO:0008385	IkappaB kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	CHUK;IKBKB;IKBKG;MAP3K7	GO:0008385 IkappaB kinase complex	1
ILF2		GO:0030687	preribosome, large subunit precursor	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|NF45-NF90 complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:1990904 ribonucleoprotein complex	1
ILF2		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|NF45-NF90 complex	AATF;IMP3;NOP56;UTP4		1
ILF3		GO:0030687	preribosome, large subunit precursor	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|NF45-NF90 complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:1990904 ribonucleoprotein complex	1
ILF3		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|NF45-NF90 complex	AATF;IMP3;NOP56;UTP4		1
IMMP1L		GO:0017087	mitochondrial processing peptidase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0005739 mitochondrion	1
IMMP1L		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
IMMP2L		GO:0017087	mitochondrial processing peptidase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0005739 mitochondrion	1
IMMP2L		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
IMMT		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
IMMT		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
IMP3		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
IMP3		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
IMP4		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
IMP4		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
ING4		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|other	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1		1
IPO11		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO11		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO13		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus	2
IPO13		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO4		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO4		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
IPO5		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0006610 ribosomal protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO5		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0006610 ribosomal protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO7		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO7		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO8		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO8		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPO9		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
IPO9		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
IPP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
IRF2BP1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|IRF2 binding	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
IRF2BP2		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|IRF2 binding	MID1;MID2;TRIM36;TRIM46;TRIM9		1
IRF2BPL		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|IRF2 binding	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
IRF8		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|IRF8 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|IRF8 transcriptional program|Transcription factor	IRF8	GO:0003700 DNA-binding transcription factor activity	1
ISG20L2		GO:0006364	rRNA processing	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006396 RNA processing	1
ISG20L2		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4		1
ITCH		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination & NEDDylation	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
ITFG2		GO:0140007	KICSTOR complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	ITFG2;KICS2;KPTN;SZT2	GO:0140007 KICSTOR complex	1
ITGB1BP2		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
IVNS1ABP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
JADE2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|other	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
JKAMP		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	DERL1;DERL2;DERL3;ERLIN1;ERLIN2;HERPUD1;JKAMP;SVIP;SYVN1;TMUB1	GO:0036503 ERAD pathway	2
JOSD1		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin|non-UIM	ATXN3;ATXN3L;JOSD1;JOSD2	GO:0101005 deubiquitinase activity	1
JOSD2		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin	Ubiquitin Proteasome System|DUBs and UBL demodifiers|Josephin|non-UIM	ATXN3;ATXN3L;JOSD1;JOSD2	GO:0101005 deubiquitinase activity	1
JUN		GO:0035976	transcription factor AP-1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|AP-1 transcriptional program|Component of AP-1 transcription factor	FOS;FOSB;FOSL1;FOSL2;JUN	GO:0035976 transcription factor AP-1 complex	1
KARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase;Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase;Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS1;AARS2;CARS1;CARS2;DARS1;DARS2;EARS2;EPRS1;FARS2;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	2
KAT2B		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|bromodomain, Acyl_CoA_acyltransferase	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91		1
KBTBD11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	no_local_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KBTBD12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KBTBD13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KBTBD2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KBTBD3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KBTBD4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KBTBD6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KBTBD7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KBTBD8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KCMF1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex|UBR4/KCMF1 complex|noncatalytic subunit;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component|idiosyncratic / noncatalytic|UBZ (Di19)	ANAPC11;ANAPC2;CALM1;FANCL;KCMF1;SHARPIN;UBR4		2
KCTD10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|KCTD11/21 CTD	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KCTD17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KCTD2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD20		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD21		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|KCTD11/21 CTD	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|WD40	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KCTD9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KDELR1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport;ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	COPA;COPB1;COPB2;COPE;COPG1;KDELR1;KDELR2;KDELR3;MYDGF	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	2
KDELR1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
KDELR2		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport;ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	COPA;COPB1;COPB2;COPE;COPG1;KDELR1;KDELR2;KDELR3;MYDGF	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	2
KDELR2		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
KDELR3		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport;ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	COPA;COPB1;COPB2;COPE;COPG1;KDELR1;KDELR2;KDELR3;MYDGF	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	2
KDELR3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
KDM2A		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR with PHD	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
KDM2B		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR with PHD	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
KEAP1		GO:0006979	response to oxidative stress	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor regulator|Oxidative stress response|NFE2L2 modulator	PN regulation|Transcription factor regulator|Oxidative stress response|NFE2L2 modulator	KEAP1	GO:0034599 cellular response to oxidative stress	1
KEAP1		GO:1900407	regulation of cellular response to oxidative stress	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor regulator|Oxidative stress response	PN regulation|Transcription factor regulator|Oxidative stress response|NFE2L2 modulator	KEAP1		1
KEAP1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KGD4		GO:0005761	mitochondrial ribosome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion	2
KGD4		GO:0005763	mitochondrial small ribosomal subunit	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion	1
KICS2		GO:0140007	KICSTOR complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	ITFG2;KICS2;KPTN;SZT2	GO:0140007 KICSTOR complex	1
KIF5B		GO:0032418	lysosome localization	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the lysosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the lysosome	KIF5B	GO:0032418 lysosome localization	1
KLHDC10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|KELCH	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHDC2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|KELCH	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHDC3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|KELCH	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL14		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KLHL15		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL18		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL20		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL21		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL22		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL23		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL24		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL25		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL26		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL28		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL29		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL30		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL31		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KLHL32		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL33		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	no_local_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KLHL34		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KLHL35		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL36		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL38		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL40		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL41		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL42		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
KLHL5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KLHL9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
KMT2A		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|SET	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1		1
KMT2B		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD|SET	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1		1
KMT2C		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|Histone-lysine N-methyltransferase	MID1;MID2;TRIM36;TRIM46;TRIM9		1
KMT2D		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|Histone-lysine N-methyltransferase	MID1;MID2;TRIM36;TRIM46;TRIM9		1
KPNA1		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA2		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA3		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA4		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA5		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA5		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA6		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA6		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNA7		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	HIKESHI;KPNA1;KPNA2;KPNA3;KPNA4;KPNA5;KPNB1;XPO1	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNA7		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, alpha type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus	1
KPNB1		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006404 RNA import into nucleus;GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0006610 ribosomal protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
KPNB1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006607 NLS-bearing protein import into nucleus;GO:0006610 ribosomal protein import into nucleus;GO:0006886 intracellular protein transport	1
KPTN		GO:0140007	KICSTOR complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	ITFG2;KICS2;KPTN;SZT2	GO:0140007 KICSTOR complex	1
KRTCAP2		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
KRTCAP2		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
KXD1		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
LAMP2		GO:0061684	chaperone-mediated autophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy;Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Receptor for chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Receptor for chaperone-mediated autophagy	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8;LAMP2	GO:0061684 chaperone-mediated autophagy	2
LAMTOR1		GO:0071986	Ragulator complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	LAMTOR1;LAMTOR2;LAMTOR3;LAMTOR4;LAMTOR5	GO:0071986 Ragulator complex	1
LAMTOR2		GO:0071986	Ragulator complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	LAMTOR1;LAMTOR2;LAMTOR3;LAMTOR4;LAMTOR5	GO:0071986 Ragulator complex	1
LAMTOR3		GO:0071986	Ragulator complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	LAMTOR1;LAMTOR2;LAMTOR3;LAMTOR4;LAMTOR5	GO:0071986 Ragulator complex	1
LAMTOR4		GO:0071986	Ragulator complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	LAMTOR1;LAMTOR2;LAMTOR3;LAMTOR4;LAMTOR5	GO:0071986 Ragulator complex	1
LAMTOR5		GO:0071986	Ragulator complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|Ragulator complex component	LAMTOR1;LAMTOR2;LAMTOR3;LAMTOR4;LAMTOR5	GO:0071986 Ragulator complex	1
LARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
LARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
LGALS3BP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
LGALS8		GO:0098792	xenophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Xenophagy	AZI2;LGALS8	GO:0098792 xenophagy	1
LGMN		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	DPP4;DPP7;GGH;LGMN;TPP1	GO:0008233 peptidase activity	1
LIPA		GO:0016298	lipase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal lipase	ABHD6;DAGLB;LIPA	GO:0016298 lipase activity	1
LLPH		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
LLPH		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4		1
LMAN1		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
LMAN1L		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
LMAN2		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
LMAN2L		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
LMBR1L		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|LMBR1L-GP78-UBAC2 complex|noncatalytic / transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
LMNB1		GO:0044804	nucleophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Nucleophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Nucleophagy	LMNB1		1
LMO7		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|LIM, PDZ	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0004842 ubiquitin-protein transferase activity	1
LNX1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PDZ|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
LNX2		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PDZ|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	1
LOC124902573		GO:0000154	rRNA modification	no_local_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3		1
LOC124902573		GO:0042254	ribosome biogenesis	no_local_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4		1
LONP1		GO:0005759	mitochondrial matrix	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005759 mitochondrial matrix	1
LONP1		GO:0035694	mitochondrial protein catabolic process	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0035694 mitochondrial protein catabolic process	1
LONRF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|LON|TPR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
LONRF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|LON|TPR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
LONRF3		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
LONRF3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml;ubiquitin_proteasome_system.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|LON|TPR	LONRF3;MID1;MID2;STUB1;TRIM36;TRIM46;TRIM9;TTC3;WDTC1	GO:0061630 ubiquitin protein ligase activity	2
LRR1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
LRRC14		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
LRRC14B		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	no_local_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
LRRC28		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|non-canonical|with LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
LRRC42		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
LRRC58		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|non-canonical|with LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
LRRK2		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
LRRK2		GO:0060590	ATPase regulator activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Regulator of the lysosomal v-ATPase proton pump	ATP6AP1;ATP6AP2;LRRK2		1
LRSAM1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|LRR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
LRSAM1		GO:0098792	xenophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy|Intracellular pathogen ubiquitination	LRSAM1;PHF23;RNF166	GO:1904417 positive regulation of xenophagy	1
LSG1		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
LSG1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0000054 ribosomal subunit export from nucleus	1
LTN1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
LTN1		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	CNOT4;HUWE1;LTN1;MKRN1;MKRN2	GO:0016567 protein ubiquitination	1
LTN1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|Armadillo-like;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|RWD (LTN1)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
LTV1		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
LTV1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
LZTR1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|KELCH	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
MAEA		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|catalytic / RING, CRA, LisH	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
MAGEA11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|SKP2 specific|MAGE	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
MAGT1		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
MAGT1		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
MALSU1		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Regulation of 28S-39S subunit association	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
MAN1B1		GO:0006487	protein N-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0140277 endoplasmic reticulum N-glycan trimming	1
MAN1B1		GO:1904382	mannose trimming involved in glycoprotein ERAD pathway	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Mannose trimming	EDEM1;EDEM2;EDEM3;MAN1B1	GO:0009100 glycoprotein metabolic process;GO:0036503 ERAD pathway	1
MAN2B1		GO:0015923	mannosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	MAN2B1;MAN2B2;MANBA	GO:0004559 alpha-mannosidase activity	1
MAN2B2		GO:0015923	mannosidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	MAN2B1;MAN2B2;MANBA	GO:0015923 mannosidase activity	1
MAN2C1		GO:0006517	protein deglycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ENGASE;MAN2C1;NGLY1		1
MAN2C1		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
MANBA		GO:0015923	mannosidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal mannosidase	MAN2B1;MAN2B2;MANBA	GO:0004567 beta-mannosidase activity	1
MAP1LC3A		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
MAP1LC3B		GO:0061739	protein lipidation involved in autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Preparation of ATG8 homologs for lipidation|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3B	GO:0000045 autophagosome assembly;GO:0006914 autophagy;GO:0016236 macroautophagy	1
MAP1LC3B		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|ATG8 homolog	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3		3
MAP1LC3B		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
MAP1LC3C		GO:0097352	autophagosome maturation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|ATG8 homolog	GABARAP;GABARAPL1;MAP1LC3A;MAP1LC3B;MAP1LC3C	GO:0097352 autophagosome maturation	1
MAP1S		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0006914 autophagy	1
MAP1S		GO:0035973	aggrephagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	MAP1S;NBR1;OPTN;SQSTM1;TOLLIP	GO:0006914 autophagy	1
MAP3K1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|kinase, SWIM-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MAP3K20		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
MAP3K7		GO:0004674	protein serine/threonine kinase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|AMPK kinase (not in a complex)	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|AMPK kinase (not in a complex)	CAMKK2;MAP3K7	GO:0004674 protein serine/threonine kinase activity	1
MAP3K7		GO:0008385	IkappaB kinase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|IKK complex component	CHUK;IKBKB;IKBKG;MAP3K7	GO:0005737 cytoplasm;GO:0005829 cytosol	1
MAPK8IP1		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|Miscellaneous function - movement of autophagosomes along microtubules	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3		2
MAPKAP1		GO:0031932	TORC2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR	GO:0031932 TORC2 complex	1
MARCHF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF10		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF11		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF5		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1		1
MARCHF5		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|mitoTAD pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
MARCHF5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF6		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
MARCHF6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
MARCHF7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF8		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARCHF9		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MARCH|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MARK2		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000422 autophagy of mitochondrion	1
MARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
MARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
MCM2		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
MCTS1		GO:0006415	translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|tRNA, mRNA release	ABCE1;EIF2D;ETF1;GSPT1;GSPT2		1
MDM2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Mdm|RanBP2-type ZNF;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / Mdm|RanBP2-type ZnF	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
MDM4		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Mdm|RanBP2-type ZNF;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / Mdm|RanBP2-type ZnF	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9		2
MEFV		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|Pyrin, ringless, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MEFV		GO:0160247	autophagy cargo adaptor activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Individual substrates	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Individual substrates	CCDC50;MEFV		1
METAP1		GO:0004239	initiator methionyl aminopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal methionine cleavage from nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal methionine cleavage from nascent peptide	METAP1;METAP2	GO:0004239 initiator methionyl aminopeptidase activity	1
METAP1D		GO:0017087	mitochondrial processing peptidase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0005739 mitochondrion	1
METAP1D		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis	1
METAP2		GO:0004239	initiator methionyl aminopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal methionine cleavage from nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal methionine cleavage from nascent peptide	METAP1;METAP2	GO:0004239 initiator methionyl aminopeptidase activity	1
METTL15		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0070475 rRNA base methylation	1
METTL15		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0180026 mitochondrial small ribosomal subunit assembly	1
MEX3A		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MEX3	MID1;MID2;TRIM36;TRIM46;TRIM9		1
MEX3B		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MEX3	MID1;MID2;TRIM36;TRIM46;TRIM9		1
MEX3C		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MEX3	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MEX3D		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|MEX3	MID1;MID2;TRIM36;TRIM46;TRIM9		1
MFN1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Modulator of mitochondrial morphology-induced mitophagy	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
MFN2		GO:0000423	mitophagy	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Modulator of mitochondrial morphology-induced mitophagy	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0061734 type 2 mitophagy	1
MGRN1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MIB1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Mindbomb	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MIB2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Mindbomb	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MICOS10		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
MICOS13		GO:0061617	MICOS complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	Mitochondrial proteostasis|Membrane protein folding|MICOS complex	APOO;CHCHD3;CHCHD6;IMMT;MICOS13	GO:0061617 MICOS complex	1
MID1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MID2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MIDN		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|UBL only	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
MIEF1		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Regulation of 28S-39S subunit association	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
MINDY1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	MINDY1;MINDY2;MINDY3;MINDY4	GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
MINDY2		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	MINDY1;MINDY2;MINDY3;MINDY4	GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
MINDY3		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	MINDY1;MINDY2;MINDY3;MINDY4	GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
MINDY4		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	Ubiquitin Proteasome System|DUBs and UBL demodifiers|MINDY	MINDY1;MINDY2;MINDY3;MINDY4	GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
MIOS		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	MIOS;SEC13;SEH1L;WDR24;WDR59	GO:0061700 GATOR2 complex	1
MIPEP		GO:0017087	mitochondrial processing peptidase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix	1
MIPEP		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
MIR124-1		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR124-1		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR124-2		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR124-2		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR124-3		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR124-3		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR224		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR224		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR24-1		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR24-1		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR24-2		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR24-2		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR27B		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR27B		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MIR488		GO:0006417	regulation of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|microRNA	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A		1
MIR488		GO:0035278	miRNA-mediated gene silencing by inhibition of translation	no_local_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|microRNA	PN regulation|Translation regulator|microRNA	MIR224;MIR24-1;MIR24-2;MIR27B;MIR488		1
MKLN1		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / LisH, KELCH	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
MKRN1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
MKRN1		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	CNOT4;HUWE1;LTN1;MKRN1;MKRN2	GO:0016567 protein ubiquitination	1
MKRN1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Makorin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MKRN2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
MKRN2		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitination	CNOT4;HUWE1;LTN1;MKRN1;MKRN2	GO:0016567 protein ubiquitination	1
MKRN2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Makorin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MKRN3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Makorin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MKRN4P		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Makorin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MLEC		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Lectin chaperone	DAD1;DDOST;MAGT1;OSTC;RPN1		1
MLST8		GO:0031931	TORC1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR	GO:0031931 TORC1 complex	1
MLST8		GO:0031932	TORC2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR	GO:0031932 TORC2 complex	1
MME		GO:0005886	plasma membrane	already_in_goa_exact	ok_for_propagation_to_go	extracellular_proteostasis.yaml	Extracellular proteostasis|Protease|Plasma membrane	Extracellular proteostasis|Protease|Plasma membrane	MME	GO:0005886 plasma membrane	1
MME		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	extracellular_proteostasis.yaml	Extracellular proteostasis|Protease	Extracellular proteostasis|Protease|Plasma membrane	IDE;MME	GO:0008233 peptidase activity	1
MMGT1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
MMGT1		GO:0044743	protein transmembrane import into intracellular organelle	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147	GO:0055085 transmembrane transport	1
MMGT1		GO:0072546	EMC complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	ER proteostasis|Protein transport|Transmembrane protein import|EMC complex component	EMC1;EMC2;EMC3;EMC4;MMGT1	GO:0072546 EMC complex	1
MNAT1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / second enzymatic function|UIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9		2
MOCS3		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of URM1	Ubiquitin Proteasome System|E1 activating enzymes|activation of URM1	MOCS3	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
MOGS		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Glucose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
MPHOSPH10		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
MPHOSPH10		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|IMP3-IMP4 complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
MPND		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	BRCC3;MPND;MYSM1	GO:0140492 metal-dependent deubiquitinase activity	1
MPV17L2		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	1
MRE11		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-C complex|MRN subcomplex / DNA binding	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
MRM1		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	MRM1;MRM2;MRM3;RPUSD4;TRMT61B	GO:0000154 rRNA modification	1
MRM1		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
MRM2		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	MRM1;MRM2;MRM3;RPUSD4;TRMT61B	GO:0000451 rRNA 2'-O-methylation;GO:0031167 rRNA methylation	1
MRM2		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
MRM3		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	MRM1;MRM2;MRM3;RPUSD4;TRMT61B	GO:0000451 rRNA 2'-O-methylation;GO:0070039 rRNA (guanosine-2'-O-ribose)-methyltransferase activity	1
MRM3		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
MRPL1		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL1		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL10		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL10		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL11		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL11		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL12		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL12		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL13		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL13		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL14		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL14		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL15		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL15		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL16		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL16		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL17		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL17		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL18		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL18		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL19		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL19		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL2		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL2		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL20		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL20		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL21		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL21		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL22		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL22		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL23		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL23		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL24		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL24		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL27		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL27		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL28		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL28		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL3		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL3		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL30		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL30		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL32		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL32		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL33		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL33		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL34		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL34		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL35		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL35		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL36		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL36		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL37		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL37		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL38		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL38		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL39		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL39		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL4		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL4		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL40		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL40		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL41		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL41		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL42		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit;GO:0005763 mitochondrial small ribosomal subunit	2
MRPL42		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL43		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL43		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL44		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL44		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL45		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL45		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL46		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL46		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL47		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL47		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL48		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL48		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL49		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL49		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL50		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL50		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL51		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL51		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL52		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL52		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL53		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL53		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL54		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL54		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL55		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL55		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL57		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL57		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL58		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPL58		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPL58		GO:0070126	mitochondrial translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR	GO:0070126 mitochondrial translational termination	1
MRPL58		GO:7770016	rescue of stalled mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	GTPBP6;MRPL58;MTRES1;MTRFR	GO:7770016 rescue of stalled mitochondrial ribosome	1
MRPL9		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPL9		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPS10		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS10		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS11		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS11		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS12		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPS12		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS14		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPS14		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS15		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPS15		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS16		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS16		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS17		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS17		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS18A		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit;GO:0005763 mitochondrial small ribosomal subunit	2
MRPS18A		GO:0005762	mitochondrial large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|39S subunit	MRPL1;MRPL2;MRPL3;MRPL4;MRPL9	GO:0005762 mitochondrial large ribosomal subunit	1
MRPS18B		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS18B		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS18C		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS18C		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS2		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS2		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS21		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS21		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS22		GO:0005761	mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005761 mitochondrial ribosome	2
MRPS22		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS23		GO:0005761	mitochondrial ribosome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion;GO:0005840 ribosome	2
MRPS23		GO:0005763	mitochondrial small ribosomal subunit	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion;GO:0005840 ribosome	1
MRPS24		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS24		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS25		GO:0005761	mitochondrial ribosome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion	2
MRPS25		GO:0005763	mitochondrial small ribosomal subunit	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion	1
MRPS26		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS26		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS27		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS27		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS28		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS28		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS30		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005762 mitochondrial large ribosomal subunit	2
MRPS30		GO:0005763	mitochondrial small ribosomal subunit	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005739 mitochondrion;GO:0005840 ribosome	1
MRPS31		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS31		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS33		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS33		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS34		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS34		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS35		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS35		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS5		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS5		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS6		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS6		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS7		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS7		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRPS9		GO:0005761	mitochondrial ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome;Translation|Mitochondrial translation|Ribosome|Mitoribosome	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	2
MRPS9		GO:0005763	mitochondrial small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	Translation|Mitochondrial translation|Ribosome|Mitoribosome|28S subunit	MRPS2;MRPS5;MRPS6;MRPS7;MRPS9	GO:0005763 mitochondrial small ribosomal subunit	1
MRTO4		GO:0030687	preribosome, large subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:0030687 preribosome, large subunit precursor	1
MRTO4		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0000027 ribosomal large subunit assembly;GO:0006364 rRNA processing;GO:0042273 ribosomal large subunit biogenesis	1
MSL1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|MSL1/MSL2 complex|noncatalytic / other	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
MSL2		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|MSL1/MSL2 complex|catalytic / RING	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
MSL2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MT-RNR2		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Stabilizer of HSP90 binding of CMA substrates	AMBRA1;GFAP;MT-RNR2;PSME1;TP53		1
MTCH1		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Insertase for helical proteins into the outer membrane	Mitochondrial proteostasis|Membrane protein folding|Insertase for helical proteins into the outer membrane	MTCH1;MTCH2	GO:0045040 protein insertion into mitochondrial outer membrane	1
MTCH2		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Insertase for helical proteins into the outer membrane	Mitochondrial proteostasis|Membrane protein folding|Insertase for helical proteins into the outer membrane	MTCH1;MTCH2	GO:0045040 protein insertion into mitochondrial outer membrane	1
MTERF3		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	1
MTERF4		GO:0000154	rRNA modification	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0006364 rRNA processing	1
MTERF4		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA chaperone	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	2
MTG1		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	GTPBP10;GTPBP6;METTL15;MTERF4;MTG1;MTG2;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	2
MTG2		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit assembly	GTPBP10;GTPBP6;METTL15;MTERF4;MTG1;MTG2;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	2
MTIF2		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3	GO:0003743 translation initiation factor activity	1
MTIF2		GO:0070124	mitochondrial translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3	GO:0070124 mitochondrial translational initiation	1
MTIF3		GO:0003743	translation initiation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3	GO:0003743 translation initiation factor activity	1
MTIF3		GO:0070124	mitochondrial translational initiation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3	GO:0070124 mitochondrial translational initiation	1
MTMR14		GO:0046856	phosphatidylinositol dephosphorylation	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	MTMR14;MTMR3;MTMR4;MTMR8;MTMR9		1
MTMR3		GO:0046856	phosphatidylinositol dephosphorylation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	MTMR14;MTMR3;MTMR4;MTMR8;MTMR9	GO:0046856 phosphatidylinositol dephosphorylation	1
MTMR4		GO:0046856	phosphatidylinositol dephosphorylation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	MTMR14;MTMR3;MTMR4;MTMR8;MTMR9	GO:0046856 phosphatidylinositol dephosphorylation	1
MTMR8		GO:0046856	phosphatidylinositol dephosphorylation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	MTMR14;MTMR3;MTMR4;MTMR8;MTMR9	GO:0046856 phosphatidylinositol dephosphorylation	1
MTMR9		GO:0046856	phosphatidylinositol dephosphorylation	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|Regulation of PI(3)P levels	MTMR14;MTMR3;MTMR4;MTMR8;MTMR9	GO:0046856 phosphatidylinositol dephosphorylation	1
MTOR		GO:0031931	TORC1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR	GO:0031931 TORC1 complex	1
MTOR		GO:0031932	TORC2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR	GO:0031932 TORC2 complex	1
MTRES1		GO:0070126	mitochondrial translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR		1
MTRES1		GO:7770016	rescue of stalled mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	GTPBP6;MRPL58;MTRES1;MTRFR	GO:7770016 rescue of stalled mitochondrial ribosome	1
MTRF1		GO:0070126	mitochondrial translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination;Translation|Mitochondrial translation|Translation termination|Normal termination	Translation|Mitochondrial translation|Translation termination|Normal termination	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR	GO:0070126 mitochondrial translational termination	2
MTRF1L		GO:0070126	mitochondrial translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination;Translation|Mitochondrial translation|Translation termination|Normal termination	Translation|Mitochondrial translation|Translation termination|Normal termination	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR	GO:0070126 mitochondrial translational termination	2
MTRFR		GO:0070126	mitochondrial translational termination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	MRPL58;MTRES1;MTRF1;MTRF1L;MTRFR	GO:0070126 mitochondrial translational termination	1
MTRFR		GO:7770016	rescue of stalled mitochondrial ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	Translation|Mitochondrial translation|Translation termination|Termination on stalled ribosomes	GTPBP6;MRPL58;MTRES1;MTRFR	GO:7770016 rescue of stalled mitochondrial ribosome	1
MTX1		GO:0005741	mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	MTX1;MTX2;MTX3;SAMM50	GO:0005741 mitochondrial outer membrane	1
MTX2		GO:0005741	mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	MTX1;MTX2;MTX3;SAMM50	GO:0005741 mitochondrial outer membrane	1
MTX3		GO:0005741	mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	MTX1;MTX2;MTX3;SAMM50	GO:0005741 mitochondrial outer membrane	1
MUL1		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1905091 positive regulation of type 2 mitophagy	1
MUL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|mitochondria, peroxisome	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MVB12A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
MVB12A		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
MVB12B		GO:0000045	autophagosome assembly	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C		1
MVB12B		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
MYCBP2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RCR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RCR	MYCBP2	GO:0061630 ubiquitin protein ligase activity	1
MYDGF		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport;ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	COPA;COPB1;COPB2;COPE;COPG1;KDELR1;KDELR2;KDELR3;MYDGF		2
MYDGF		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|Receptor for KDEL-containing proteins for retrograde transport	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
MYLIP		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
MYO6		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	ARL8A;ARL8B;CALCOCO2;MAP1LC3B;MYO6;RILP;RUFY3;TAX1BP1;TOM1		2
MYSM1		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|assorted	BRCC3;MPND;MYSM1	GO:0140492 metal-dependent deubiquitinase activity	1
MZB1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	ER proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|Folding of IGM and IgA	CNPY3;MZB1	GO:0005515 protein binding	1
N4BP1		GO:1990948	ubiquitin ligase inhibitor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase inhibitor	Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase inhibitor|ITCH inhibitor|UBA (N4BP1)	N4BP1		1
NAA10		GO:0006474	N-terminal protein amino acid acetylation	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatA/NatE complex component	NAA10;NAA15;NAA20;NAA25;NAA30	GO:0051604 protein maturation	1
NAA15		GO:0006474	N-terminal protein amino acid acetylation	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatA/NatE complex component	NAA10;NAA15;NAA20;NAA25;NAA30	GO:0051604 protein maturation	1
NAA20		GO:0006474	N-terminal protein amino acid acetylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatB complex component	NAA10;NAA15;NAA20;NAA25;NAA30	GO:0006474 N-terminal protein amino acid acetylation	1
NAA25		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatB complex component	NAA10;NAA15;NAA20;NAA25;NAA30		1
NAA30		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatC complex component	NAA10;NAA15;NAA20;NAA25;NAA30		1
NAA35		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatC complex component	NAA10;NAA15;NAA20;NAA25;NAA30		1
NAA38		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatC complex component	NAA10;NAA15;NAA20;NAA25;NAA30		1
NAA40		GO:0006474	N-terminal protein amino acid acetylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatD, sole component	NAA10;NAA15;NAA20;NAA25;NAA30		1
NAA50		GO:0006474	N-terminal protein amino acid acetylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatE complex component	NAA10;NAA15;NAA20;NAA25;NAA30	GO:0006474 N-terminal protein amino acid acetylation	1
NAAA		GO:0017064	fatty acid amide hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal fatty acid amidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal fatty acid amidase	NAAA	GO:0017064 fatty acid amide hydrolase activity	1
NACA		GO:0005854	nascent polypeptide-associated complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	BTF3;NACA;NACA2;NACAD	GO:0005854 nascent polypeptide-associated complex	1
NACA2		GO:0005854	nascent polypeptide-associated complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	BTF3;NACA;NACA2;NACAD	GO:0005854 nascent polypeptide-associated complex	1
NACAD		GO:0005854	nascent polypeptide-associated complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	Translation|Cytosolic translation|Nascent peptide husbandry|Nascent peptide sorting|NAC component	BTF3;NACA;NACA2;NACAD	GO:0005854 nascent polypeptide-associated complex	1
NAE1		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of NEDD8	Ubiquitin Proteasome System|E1 activating enzymes|activation of NEDD8	NAE1;UBA3	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
NAGA		GO:0008456	alpha-N-acetylgalactosaminidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Lysosomal glycosyl deacetylase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Lysosomal glycosyl deacetylase	NAGA	GO:0008456 alpha-N-acetylgalactosaminidase activity	1
NAGLU		GO:0016798	hydrolase activity, acting on glycosyl bonds	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparinase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparinase	HPSE;NAGLU	GO:0004561 alpha-N-acetylglucosaminidase activity	1
NAP1L1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1		1
NAP1L1		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
NAP1L2		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NAP1L3		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NAP1L4		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NAP1L5		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
NARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
NASP		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|TPR domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
NASP		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NAT10		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000154 rRNA modification	1
NAT10		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000154 rRNA modification;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis;GO:1904812 rRNA acetylation involved in maturation of SSU-rRNA	1
NBN		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-C complex|MRN subcomplex /  BRCT	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
NBR1		GO:0000425	pexophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	NBR1;PJVK;SQSTM1	GO:0016236 macroautophagy	1
NBR1		GO:0035973	aggrephagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	MAP1S;NBR1;OPTN;SQSTM1;TOLLIP	GO:0016236 macroautophagy	1
NBR1		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	NBR1;SQSTM1;TRIM17	GO:0016236 macroautophagy	1
NCL		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NCLN		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
NCLN		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
NCOA4		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Ferritinophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Ferritinophagy	NCOA4	GO:0006914 autophagy	1
NCOR1		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Derepresses transcription of CMA components	NCOR1;NFATC1		1
NDC1		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NDC1		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0015031 protein transport	1
NDUFAB1		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Regulation of 28S-39S subunit association	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
NEDD4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
NEDD4L		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
NEIL3		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA glycosylase|RanBP2-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
NEMF		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
NEU1		GO:0016997	alpha-sialidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialidase	NEU1;NEU4	GO:0004308 exo-alpha-sialidase activity	1
NEU4		GO:0016997	alpha-sialidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialidase	NEU1;NEU4	GO:0004308 exo-alpha-sialidase activity	1
NEURL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Neuralized|SPRY / NHR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NEURL1B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Neuralized|SPRY / NHR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NEURL3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Neuralized|SPRY / NHR	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NFATC1		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Promotes transcription of LAMP2	NCOR1;NFATC1		1
NFE2L1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Proteasome recovery pathway|Transcription of proteasome genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
NFE2L2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFE2L2 transcriptional program|Transcription factor;PN regulation|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|NFE2L2 transcriptional program|Transcription factor;PN regulation|Transcription factor|Oxidative stress response|Transcription of oxidative response genes	HIF1A;HSF1;HSF2;HSF4;HSF5;NFE2L2	GO:0003700 DNA-binding transcription factor activity	2
NFE2L2		GO:1900407	regulation of cellular response to oxidative stress	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Oxidative stress response;PN regulation|Transcription factor|Oxidative stress response|Transcription of oxidative response genes	PN regulation|Transcription factor|Oxidative stress response|Transcription of oxidative response genes	NFE2L2	GO:1900407 regulation of cellular response to oxidative stress	2
NFKB1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
NFKB1		GO:0006954	inflammatory response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Inflammatory response	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0006954 inflammatory response	1
NFKB1		GO:0071159	NF-kappaB complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0035525 NF-kappaB p50/p65 complex	2
NFKB2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
NFKB2		GO:0006954	inflammatory response	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Inflammatory response	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB		1
NFKB2		GO:0071159	NF-kappaB complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0005634 nucleus	2
NFX1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|NFX|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NFXL1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|NFX|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9		1
NGDN		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	BOP1;DDX27;PELP1;PES1;WDR12		1
NGDN		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
NGLY1		GO:0006517	protein deglycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	ENGASE;MAN2C1;NGLY1		1
NGLY1		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|Deglycosylation of ERAD substrates	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
NGRN		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	1
NHLRC1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|TOL	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NHP2		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000454 snoRNA guided rRNA pseudouridine synthesis;GO:0031118 rRNA pseudouridine synthesis	1
NHP2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000454 snoRNA guided rRNA pseudouridine synthesis;GO:0031118 rRNA pseudouridine synthesis	1
NIPBL		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|cohesin loading|UBM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:1990414 replication-born double-strand break repair via sister chromatid exchange	1
NIPSNAP1		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Recruitment of cargo adapters	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000423 mitophagy	1
NIPSNAP2		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Recruitment of cargo adapters	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000423 mitophagy	1
NKRF		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex	BOP1;DDX27;PELP1;PES1;WDR12		1
NKRF		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex	AATF;IMP3;NOP56;UTP4		1
NKTR		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
NLN		GO:0005758	mitochondrial intermembrane space	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ATP23;HTRA2;NLN	GO:0005758 mitochondrial intermembrane space	1
NLN		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Intermembrane space protease	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
NLRX1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
NMD3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S export adapter	AATF;IMP3;NOP56;UTP4	GO:0000055 ribosomal large subunit export from nucleus	1
NMT1		GO:0006499	N-terminal protein myristoylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal myristoylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal myristoylation of nascent peptide	NMT1;NMT2	GO:0006499 N-terminal protein myristoylation	1
NMT2		GO:0006499	N-terminal protein myristoylation	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal myristoylation of nascent peptide	Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal myristoylation of nascent peptide	NMT1;NMT2	GO:0018008 N-terminal peptidyl-glycine N-myristoylation	1
NOA1		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|Specific function in mitoribosome biogenesis unknown	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	1
NOB1		GO:0006364	rRNA processing	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006364 rRNA processing	1
NOB1		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
NOB1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex;Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	2
NOC4L		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
NOC4L		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
NOL10		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	BOP1;DDX27;PELP1;PES1;WDR12		1
NOL10		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|ANN complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1
NOL11		GO:0032040	small-subunit processome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0005634 nucleus;GO:0005730 nucleolus	1
NOL11		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA	1
NOL6		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
NOL6		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
NOMO1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
NOMO1		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
NOMO2		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
NOMO2		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
NOMO3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
NOMO3		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
NOP10		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000454 snoRNA guided rRNA pseudouridine synthesis;GO:0031118 rRNA pseudouridine synthesis	1
NOP10		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
NOP14		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
NOP14		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	AATF;IMP3;NOP56;UTP4	GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
NOP2		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0070475 rRNA base methylation	1
NOP2		GO:0032040	small-subunit processome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0005634 nucleus;GO:0005730 nucleolus	1
NOP2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex;Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000027 ribosomal large subunit assembly;GO:0000470 maturation of LSU-rRNA;GO:0006364 rRNA processing;GO:0042273 ribosomal large subunit biogenesis;GO:0070475 rRNA base methylation	2
NOP53		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
NOP53		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0000027 ribosomal large subunit assembly;GO:0006364 rRNA processing	1
NOP56		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
NOP56		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0000451 rRNA 2'-O-methylation;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
NOP58		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
NOP58		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0000451 rRNA 2'-O-methylation;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
NOSIP		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|split UBOX	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
NPLOC4		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ubiquitin recognition	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
NPLOC4		GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|VCP and associated proteins|associated DUBs|MPN|UBXL	Ubiquitin Proteasome System|VCP and associated proteins|associated DUBs|MPN|UBXL	NPLOC4	GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex	1
NPLOC4		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
NPM1		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NPM2		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NPM3		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
NPRL2		GO:1990130	GATOR1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	DEPDC5;NPRL2;NPRL3	GO:1990130 GATOR1 complex	1
NPRL3		GO:1990130	GATOR1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex component	DEPDC5;NPRL2;NPRL3	GO:1990130 GATOR1 complex	1
NSD2		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|Histone-lysine N-methyltransferase	MID1;MID2;TRIM36;TRIM46;TRIM9		1
NSMCE1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
NSUN4		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0031167 rRNA methylation	1
NSUN4		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:1902775 mitochondrial large ribosomal subunit assembly	1
NSUN5		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0070475 rRNA base methylation	1
NSUN5		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0070475 rRNA base methylation	1
NUB1		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
NUDC		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
NUDCD1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
NUDCD2		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
NUDCD3		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
NUFIP1		GO:0034517	ribophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Ribophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Ribophagy	NUFIP1		1
NUP107		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP107		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP133		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP133		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP153		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml;ubiquitin_proteasome_system.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit|mRNA, protein export|RanBP2-type ZnF	GLE1;NUP153;NUP214;NUP88;RAE1;RANBP2;SEC13;SEH1L	GO:0005643 nuclear pore	2
NUP153		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP155		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP155		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP160		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP160		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP188		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP188		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP205		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP205		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP210		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP210		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP214		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP214		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
NUP35		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP35		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
NUP37		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP37		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP42		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP42		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus	1
NUP43		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP43		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP50		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP50		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP54		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP54		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
NUP58		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP58		GO:0015031	protein transport	supported_by_goa_regulation	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0042306 regulation of protein import into nucleus	1
NUP62		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP62		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP62CL		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP62CL		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
NUP85		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP85		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP88		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP88		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP93		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP93		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NUP98		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
NUP98		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
NXF1		GO:0016973	poly(A)+ mRNA export from nucleus	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export|mRNA export|UBA-like (TAC)	NXF1;NXF2;NXF2B	GO:0016973 poly(A)+ mRNA export from nucleus	1
NXF2		GO:0016973	poly(A)+ mRNA export from nucleus	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export|mRNA export|UBA-like (TAC)	NXF1;NXF2;NXF2B	GO:0016973 poly(A)+ mRNA export from nucleus	1
NXF2B		GO:0016973	poly(A)+ mRNA export from nucleus	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA export|mRNA export|UBA-like (TAC)	NXF1;NXF2;NXF2B	GO:0016973 poly(A)+ mRNA export from nucleus	1
OASL		GO:0003725	double-stranded RNA binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|nucleic acid processes|double-stranded RNA binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|nucleic acid processes|double-stranded RNA binding	OASL	GO:0003725 double-stranded RNA binding	1
OAZ1		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|antizyme	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
OBI1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ODF1		GO:0044183	protein folding chaperone	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	Cytonuclear proteostasis|Chaperone|small HSP system|small HSP	HSPB1;HSPB2;HSPB3;HSPB6;HSPB7		1
OGT		GO:0006493	protein O-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|O-GlcNAclyation	Translation|Cytosolic translation|Ribosome-associated QC|O-GlcNAclyation	OGT	GO:0006493 protein O-linked glycosylation	1
OGT		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|O-GlcNAclyation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
OMA1		GO:0005759	mitochondrial matrix	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005739 mitochondrion	1
OMA1		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
OPTN		GO:0000423	mitophagy	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0061734 type 2 mitophagy	1
OPTN		GO:0035973	aggrephagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	MAP1S;NBR1;OPTN;SQSTM1;TOLLIP		1
OPTN		GO:0098792	xenophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	CALCOCO2;OPTN;SQSTM1;TAX1BP1;TRIM5	GO:1904417 positive regulation of xenophagy	1
OS9		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
OSBPL1A		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Recruitment of autophagosome to vicinity of ER	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Recruitment of autophagosome to vicinity of ER	ARL8A;ARL8B;MAP1LC3B;OSBPL1A;RILP;RUFY3;VAPA		2
OSTC		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
OSTC		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
OSTM1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|other	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91		1
OTUB1		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
OTUB1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	OTUB1;USP14;USP19;YOD1	GO:0004843 cysteine-type deubiquitinase activity	1
OTUD3		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
OTUD3		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination	OTUD3;USP10;USP21	GO:0004843 cysteine-type deubiquitinase activity	1
OXA1L		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|For assembly of inner membrane complexes	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
OXA1L		GO:0032977	membrane insertase activity	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|For assembly of inner membrane complexes	Mitochondrial proteostasis|Protein transport|Inner membrane import|For assembly of inner membrane complexes	OXA1L	GO:0032977 membrane insertase activity	1
P3H1		GO:0032964	collagen biosynthetic process	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032963 collagen metabolic process	1
P3H2		GO:0032964	collagen biosynthetic process	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032963 collagen metabolic process	1
P3H3		GO:0032964	collagen biosynthetic process	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032964 collagen biosynthetic process	1
P4HA1		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
P4HA2		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
P4HA3		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
P4HB		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
P4HB		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
PAAF1		GO:0043248	proteasome assembly	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle|WD40	PAAF1;POMP;PSMD10;PSMD5;PSMD9;PSMG1;PSMG2;PSMG3;PSMG4		2
PABPC1		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC1		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC1L		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC1L		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC1L2A		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC1L2A		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC1L2B		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC1L2B		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC3		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC3		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC4		GO:0003743	translation initiation factor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H	GO:0006412 translation	1
PABPC4		GO:0006413	translational initiation	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B	GO:0006412 translation	1
PABPC4L		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC4L		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PABPC5		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
PABPC5		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
PAM16		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
PAM16		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0030150 protein import into mitochondrial matrix	1
PARK7		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Modulator of mitochondrial morphology-induced mitophagy	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
PARK7		GO:0005759	mitochondrial matrix	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005759 mitochondrial matrix	1
PARK7		GO:0035694	mitochondrial protein catabolic process	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0007005 mitochondrion organization	1
PARL		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901524 regulation of mitophagy	1
PARN		GO:0006364	rRNA processing	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP		1
PARN		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4		1
PARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
PCGF1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9		2
PCGF2		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9		2
PCGF3		GO:0061630	ubiquitin protein ligase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9	GO:0140862 histone H2AK119 ubiquitin ligase activity	2
PCGF5		GO:0061630	ubiquitin protein ligase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9	GO:0140862 histone H2AK119 ubiquitin ligase activity	2
PCGF6		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9		2
PCYOX1		GO:0001735	prenylcysteine oxidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-prenylation	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-prenylation	PCYOX1	GO:0001735 prenylcysteine oxidase activity	1
PDCD6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate adaptor|KLHL12 specific|EF hand	PDCD6;PEF1	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PDCD6IP		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|Localization of the ESCRT-III complex	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
PDCL3		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
PDF		GO:0034982	mitochondrial protein processing	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Methionine deformylation	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3		1
PDF		GO:0042586	peptide deformylase activity	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Methionine deformylation	Mitochondrial proteostasis|Mitochondrial protein maturation|Methionine deformylation	PDF	GO:0042586 peptide deformylase activity	1
PDIA2		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDIA3		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDIA4		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDIA5		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDIA6		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDILT		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
PDLIM2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|BTRC specific	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
PDZRN3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PDZ|TRAF-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PDZRN4		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PDZ|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
PEF1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate adaptor|KLHL12 specific|EF hand	PDCD6;PEF1	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PELI1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Pellino	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PELI2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Pellino	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PELI3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Pellino	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PELO		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
PELO		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
PELP1		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	BOP1;DDX27;PELP1;PES1;WDR12		1
PELP1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	AATF;IMP3;NOP56;UTP4	GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing	1
PES1		GO:0030687	preribosome, large subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:0030687 preribosome, large subunit precursor	1
PES1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
PEX10		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PEX|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PEX12		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PEX|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	1
PEX2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|PEX|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PEX5		GO:0000425	pexophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Pexophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Pexophagy	PEX5	GO:0000425 pexophagy	1
PGAM5		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0016236 macroautophagy	1
PGGHG		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
PHB2		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0000423 mitophagy	1
PHF23		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy|Suppressor of intracellular pathogen ubiquitination	LRSAM1;PHF23;RNF166		1
PHF7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PHIP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|bromodomain	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
PHLPP1		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of LAMP2A multimerization	AMBRA1;GFAP;MT-RNR2;PSME1;TP53		1
PHRF1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
PI4KB		GO:0004430	1-phosphatidylinositol 4-kinase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|PI(4)P production	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|PI(4)P production	PI4KB	GO:0004430 1-phosphatidylinositol 4-kinase activity	1
PICALM		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex regulator	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex regulator	PICALM;STX7;STX8;VAMP3;VAMP7;VTI1B		2
PIH1D1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
PIH1D2		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
PIK3C3		GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	ATG14;BECN1;BECN2;PIK3C3;PIK3R4	GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I	1
PIK3C3		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG	GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II	1
PIK3CA		GO:0005943	phosphatidylinositol 3-kinase complex, class IA	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	PIK3CA;PIK3CB;PIK3CD;PIK3R1;PIK3R2	GO:0005943 phosphatidylinositol 3-kinase complex, class IA	1
PIK3CB		GO:0005943	phosphatidylinositol 3-kinase complex, class IA	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	PIK3CA;PIK3CB;PIK3CD;PIK3R1;PIK3R2	GO:0005943 phosphatidylinositol 3-kinase complex, class IA	1
PIK3CD		GO:0005943	phosphatidylinositol 3-kinase complex, class IA	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	PIK3CA;PIK3CB;PIK3CD;PIK3R1;PIK3R2	GO:0005943 phosphatidylinositol 3-kinase complex, class IA	1
PIK3R1		GO:0005943	phosphatidylinositol 3-kinase complex, class IA	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	PIK3CA;PIK3CB;PIK3CD;PIK3R1;PIK3R2	GO:0005943 phosphatidylinositol 3-kinase complex, class IA	1
PIK3R2		GO:0005943	phosphatidylinositol 3-kinase complex, class IA	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PI3K complex component	PIK3CA;PIK3CB;PIK3CD;PIK3R1;PIK3R2	GO:0005943 phosphatidylinositol 3-kinase complex, class IA	1
PIK3R4		GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Class 3 PI3K complex 1, direct|Class 3 PI3K complex 1 component	ATG14;BECN1;BECN2;PIK3C3;PIK3R4	GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I	1
PIK3R4		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG	GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II	1
PINK1		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000423 mitophagy	1
PINK1		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Promotion of MDV formation by ubiquitination of substrates	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Promotion of MDV formation by ubiquitination of substrates	PINK1;PRKN	GO:0016567 protein ubiquitination	1
PITHD1		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator|PITH	ECPAS;PITHD1;PSME4;PSMF1		1
PITRM1		GO:0005759	mitochondrial matrix	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005759 mitochondrial matrix	1
PITRM1		GO:0035694	mitochondrial protein catabolic process	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0030163 protein catabolic process	1
PJA1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Praja	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PJA2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Praja	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
PJVK		GO:0000425	pexophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	NBR1;PJVK;SQSTM1	GO:0000425 pexophagy	1
PLA2G10		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004620 glycerophospholipase activity;GO:0004623 A2-type glycerophospholipase activity	1
PLA2G15		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004622 phosphatidylcholine lysophospholipase A1 activity;GO:0004623 A2-type glycerophospholipase activity;GO:0008970 glycerophospholipid phospholipase A1 activity	1
PLA2G4E		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004620 glycerophospholipase activity;GO:0004623 A2-type glycerophospholipase activity;GO:0008970 glycerophospholipid phospholipase A1 activity	1
PLA2G5		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004623 A2-type glycerophospholipase activity	1
PLAA		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	PLAA;UBXN6;YOD1	GO:0016236 macroautophagy	2
PLBD1		GO:0120569	phospholipase activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1		1
PLBD2		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004620 glycerophospholipase activity	1
PLD1		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004630 D-type glycerophospholipase activity	1
PLD3		GO:0120569	phospholipase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0003824 catalytic activity	1
PLEKHM1		GO:0097352	autophagosome maturation	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|Bridges ATG8 and HOPS complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|Bridges ATG8 and HOPS complex	PLEKHM1		1
PLOD1		GO:0032964	collagen biosynthetic process	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032964 collagen biosynthetic process	1
PLOD2		GO:0032964	collagen biosynthetic process	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032964 collagen biosynthetic process	1
PLOD3		GO:0032964	collagen biosynthetic process	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1	GO:0032964 collagen biosynthetic process	1
PML		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|various CTD;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRIM class V|SIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061659 ubiquitin-like protein ligase activity	2
PMPCA		GO:0017087	mitochondrial processing peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0017087 mitochondrial processing peptidase complex	1
PMPCA		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
PMPCB		GO:0017087	mitochondrial processing peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0017087 mitochondrial processing peptidase complex	1
PMPCB		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
PNO1		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
PNO1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
POLH		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA polymerase|UBZ3-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
POLI		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA polymerase|UBM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
POLK		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA polymerase|UBZ4-type ZnF	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
POM121		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
POM121		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
POM121C		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
POM121C		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
POM121L12		GO:0005643	nuclear pore	no_local_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
POM121L12		GO:0015031	protein transport	no_local_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
POM121L2		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
POM121L2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
POMP		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	POMP;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
POMT1		GO:0006493	protein O-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0006493 protein O-linked glycosylation	2
POMT2		GO:0006493	protein O-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0006493 protein O-linked glycosylation	2
PON2		GO:0004064	arylesterase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal arylesterase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal arylesterase	PON2	GO:0004064 arylesterase activity	1
PPARA		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|transcription factor	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91		1
PPARG		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|transcription factor	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91		1
PPIA		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4A		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4C		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4D		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4E		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4F		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIAL4G		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIB		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	CAMLG;FKBP2;FKBP7;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIB		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
PPIC		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	ER proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	CAMLG;FKBP2;FKBP7;PPIB;PPIC	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPID		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPID		GO:0031072	heat shock protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and PPIase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0031072 heat shock protein binding	1
PPIE		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIF		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Folding enzyme|Peptidyl-prolyl isomerases	Mitochondrial proteostasis|Folding enzyme|Peptidyl-prolyl isomerases	PPIF	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	1
PPIG		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIH		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIL1		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIL2		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C		2
PPIL2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|other	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
PPIL3		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIL4		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PPIL6		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C		2
PPP1R11		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|other	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
PPP1R15A		GO:0006417	regulation of translation	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0006446 regulation of translational initiation;GO:0032058 positive regulation of translational initiation in response to stress;GO:0036490 regulation of translation in response to endoplasmic reticulum stress;GO:0043558 regulation of translational initiation in response to stress	1
PPP1R15A		GO:0032055	negative regulation of translation in response to stress	more_specific_than_existing_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	PPP1R15A;PPP1R15B	GO:0051246 regulation of protein metabolic process	1
PPP1R15A		GO:0140467	integrated stress response signaling	supported_by_goa_regulation	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:1903898 negative regulation of PERK-mediated unfolded protein response	1
PPP1R15B		GO:0006417	regulation of translation	more_specific_than_existing_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:0051246 regulation of protein metabolic process	1
PPP1R15B		GO:0032055	negative regulation of translation in response to stress	more_specific_than_existing_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	PPP1R15A;PPP1R15B	GO:0051246 regulation of protein metabolic process	1
PPP1R15B		GO:0140467	integrated stress response signaling	supported_by_goa_regulation	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Translation regulator|Integrated stress response	PN regulation|Translation regulator|Integrated stress response|Dephosphorylation of EIF2alpha/EIF2S1	EIF2AK1;EIF2AK2;EIF2AK3;EIF2AK4;PPP1R15A	GO:1903898 negative regulation of PERK-mediated unfolded protein response	1
PPP5C		GO:0031072	heat shock protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and phosphatase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0031072 heat shock protein binding	1
PPT1		GO:0098599	palmitoyl hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-palmitoylation	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-palmitoylation	PPT1;PPT2	GO:0098599 palmitoyl hydrolase activity	1
PPT2		GO:0098599	palmitoyl hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-palmitoylation	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal de-palmitoylation	PPT1;PPT2	GO:0098599 palmitoyl hydrolase activity	1
PPWD1		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	2
PRAME		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF10		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF11		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF12		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF13		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF14		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF15		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF17		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF18		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF19		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF20		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF22		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF25		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF26		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF27		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF33		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF7		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRAMEF9		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|PRAME (with LRR)	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
PRDX1		GO:0051920	peroxiredoxin activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peroxiredoxins	ER proteostasis|Folding enzyme|Peroxiredoxins	PRDX1;PRDX3;PRDX4	GO:0051920 peroxiredoxin activity	1
PRDX3		GO:0051920	peroxiredoxin activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peroxiredoxins	ER proteostasis|Folding enzyme|Peroxiredoxins	PRDX1;PRDX3;PRDX4	GO:0051920 peroxiredoxin activity	1
PRDX4		GO:0051920	peroxiredoxin activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Peroxiredoxins	ER proteostasis|Folding enzyme|Peroxiredoxins	PRDX1;PRDX3;PRDX4	GO:0051920 peroxiredoxin activity	1
PRDX6		GO:0120569	phospholipase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal phospholipase	PLA2G10;PLA2G15;PLA2G4E;PLA2G5;PLBD1	GO:0004623 A2-type glycerophospholipase activity	1
PREB		GO:0005085	guanyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|SAR1A/B guanine nucleotide exchange factor	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|SAR1A/B guanine nucleotide exchange factor	PREB	GO:0005085 guanyl-nucleotide exchange factor activity	1
PREB		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|SAR1A/B guanine nucleotide exchange factor	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
PREB		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|SAR1A/B guanine nucleotide exchange factor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0042953 lipoprotein transport	1
PRKAA1		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAA2		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAB1		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAB2		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKACA		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKACB		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKACG		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKAG1		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAG2		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAG3		GO:0031588	nucleotide-activated protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex component	PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1	GO:0031588 nucleotide-activated protein kinase complex	1
PRKAR1A		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKAR1B		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKAR2A		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKAR2B		GO:0005952	cAMP-dependent protein kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|AMPK signaling pathway, direct|AMPK complex modulator by phosphorylation|PKA complex component	PRKACA;PRKACB;PRKACG;PRKAR1A;PRKAR1B	GO:0005952 cAMP-dependent protein kinase complex	1
PRKCSH		GO:0006487	protein N-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Glucose trimming	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006491 N-glycan processing	1
PRKN		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:0000423 mitophagy	1
PRKN		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Promotion of MDV formation by ubiquitination of substrates	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Promotion of MDV formation by ubiquitination of substrates	PINK1;PRKN	GO:0016567 protein ubiquitination	1
PRKN		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / Parkin	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|UBL;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|RING, UBL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / Parkin	ANKIB1;ARIH1;ARIH2;PRKN;RBCK1;RNF31;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	3
PRORP		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|pre-rRNA processing nuclease|Subunit of RNAse P complex	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
PRPF19		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|WD40	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
PRPF8		GO:0048024	regulation of mRNA splicing, via spliceosome	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|idiosyncratic Ub binding / MPN	RBM10;RBM44;RBM5;RBM6;ZRANB2	GO:0048025 negative regulation of mRNA splicing, via spliceosome	1
PRTN3		GO:0008233	peptidase activity	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protease	CTSA;CTSB;CTSC;CTSD;CTSF	GO:0004252 serine-type endopeptidase activity;GO:0008236 serine-type peptidase activity	1
PSAP		GO:0030290	sphingolipid activator protein activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|General activator of glycosphingolipid degradation	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|General activator of glycosphingolipid degradation	PSAP		1
PSMA1		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA1		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA2		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA2		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA3		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA3		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA4		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA4		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA5		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA5		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA6		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA6		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA7		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA7		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMA8		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMA8		GO:0019773	proteasome core complex, alpha-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|alpha subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0019773 proteasome core complex, alpha-subunit complex	1
PSMB1		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB1		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB10		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB10		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB11		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB11		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB2		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB2		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB3		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB3		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB4		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB4		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB5		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB5		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB6		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB6		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB7		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB7		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|constitutive	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB8		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB8		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMB9		GO:0005839	proteasome core complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMA1;PSMA2;PSMA3;PSMA4;PSMA5	GO:0005839 proteasome core complex	1
PSMB9		GO:0019774	proteasome core complex, beta-subunit complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome core particle subunit|beta subunit|specialized	PSMB1;PSMB2;PSMB3;PSMB4;PSMB5	GO:0019774 proteasome core complex, beta-subunit complex	1
PSMC1		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMC1		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC2		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC2		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC3		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC3		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC4		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC4		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC5		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMC5		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC6		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMC6		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, ATPase|with OB domain	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMD1		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|Armadillo-like	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD1		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|Armadillo-like	ADRM1;PSMD1;PSMD2;PSMD4	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMD10		GO:0043248	proteasome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle|ankyrin	PAAF1;POMP;PSMD10;PSMD5;PSMD9;PSMG1;PSMG2;PSMG3;PSMG4	GO:0070682 proteasome regulatory particle assembly	2
PSMD11		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD11		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD12		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD12		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD13		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD13		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD14		GO:0000502	proteasome complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / MPN	ADRM1;PSMD14;PSMD2;PSMD4	GO:0000502 proteasome complex	1
PSMD14		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / MPN	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|MPN;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / MPN	ADRM1;PSMC1;PSMC2;PSMC3;PSMC4;PSMC5;PSMD14;PSMD2;PSMD4	GO:0008541 proteasome regulatory particle, lid subcomplex	3
PSMD14		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|MPN	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD14		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|proteasomal	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|proteasomal	PSMD14	GO:0140492 metal-dependent deubiquitinase activity	1
PSMD2		GO:0000502	proteasome complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / alpha solenoid	ADRM1;PSMD14;PSMD2;PSMD4	GO:0000502 proteasome complex	1
PSMD2		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / alpha solenoid	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|Armadillo-like;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / alpha solenoid	ADRM1;PSMC1;PSMC2;PSMC3;PSMC4;PSMC5;PSMD14;PSMD2;PSMD4	GO:0005838 proteasome regulatory particle	3
PSMD2		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|Armadillo-like	ADRM1;PSMD1;PSMD2;PSMD4	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMD3		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD3		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD4		GO:0000502	proteasome complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits	Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|UIM, idiosyncratic Ub binding / VWA	ADRM1;PSMD14;PSMD2;PSMD4	GO:0000502 proteasome complex	1
PSMD4		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|UIM, idiosyncratic Ub binding / VWA	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|VWA, UIM;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|UIM, idiosyncratic Ub binding / VWA	ADRM1;PSMC1;PSMC2;PSMC3;PSMC4;PSMC5;PSMD14;PSMD2;PSMD4	GO:0008540 proteasome regulatory particle, base subcomplex	3
PSMD4		GO:0008540	proteasome regulatory particle, base subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|VWA, UIM	ADRM1;PSMD1;PSMD2;PSMD4	GO:0008540 proteasome regulatory particle, base subcomplex	1
PSMD5		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle|Armadillo-like	PAAF1;POMP;PSMD10;PSMD5;PSMD9;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
PSMD6		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD6		GO:0008541	proteasome regulatory particle, lid subcomplex	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0000502 proteasome complex;GO:0005838 proteasome regulatory particle;GO:0022624 proteasome accessory complex;GO:0032991 protein-containing complex	1
PSMD7		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|MPN	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD7		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|MPN	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD8		GO:0005838	proteasome regulatory particle	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0005838 proteasome regulatory particle	1
PSMD8		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|PCI	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
PSMD9		GO:0043248	proteasome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|regulatory particle|PDZ	PAAF1;POMP;PSMD10;PSMD5;PSMD9;PSMG1;PSMG2;PSMG3;PSMG4	GO:0070682 proteasome regulatory particle assembly	2
PSME1		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA|PA28	PSME1;PSME2;PSME3		1
PSME1		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of interaction between substrate and lysosome-p53	AMBRA1;GFAP;MT-RNR2;PSME1;TP53		1
PSME2		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA|PA28	PSME1;PSME2;PSME3		1
PSME3		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|activator, AAA|PA28	PSME1;PSME2;PSME3		1
PSME4		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator|Armadillo-like	ECPAS;PITHD1;PSME4;PSMF1	GO:0070628 proteasome binding	1
PSMF1		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome activators and inhibitors|modulator|PI31	ECPAS;PITHD1;PSME4;PSMF1	GO:0070628 proteasome binding	1
PSMG1		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	POMP;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
PSMG2		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	POMP;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
PSMG3		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	POMP;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
PSMG4		GO:0043248	proteasome assembly	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone;Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome assembly chaperone|core particle	POMP;PSMG1;PSMG2;PSMG3;PSMG4	GO:0043248 proteasome assembly	2
PSTK		GO:0004812	aminoacyl-tRNA ligase activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA		1
PTCD1		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA chaperone	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
PTCD3		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3		1
PTCD3		GO:0070124	mitochondrial translational initiation	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation initiation	Translation|Mitochondrial translation|Translation initiation|assorted initiation factors	MTIF2;MTIF3;PTCD3	GO:0032543 mitochondrial translation	1
PTEN		GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PIP3 dephosphorylation	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|PIP3 dephosphorylation	PTEN	GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	1
PTGES3		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
PWP2		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
PWP2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0000028 ribosomal small subunit assembly;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
PYGB		GO:0008184	glycogen phosphorylase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal phosphorylase for glycogen catabolism	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal phosphorylase for glycogen catabolism	PYGB	GO:0008184 glycogen phosphorylase activity	1
QARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
QRSL1		GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex;Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	Translation|Mitochondrial translation|Translation elongation|Amidotransferase complex|Conversion of Glu-tRNA(Gln) to Gln-tRNA(Gln)	GATB;GATC;QRSL1	GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex	2
QSOX1		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
QSOX2		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
RAB11A		GO:1904715	negative regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Promotes transport of LAMP2A to the lysosome	BMAL1;RAB11A;RARA		1
RAB17		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Xenophagy	RAB17;RAB23		1
RAB23		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Xenophagy	RAB17;RAB23		1
RAB26		GO:0160247	autophagy cargo adaptor activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Synaptophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Synaptophagy	RAB26		1
RAB2A		GO:0097352	autophagosome maturation	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|Bridges STX17, RUBCNL and HOPS complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Recruitment of HOPS complex to autophagosome|Bridges STX17, RUBCNL and HOPS complex	RAB2A	GO:0016236 macroautophagy	1
RAB5IF		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|GEL complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
RAB5IF		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|GEL complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
RAB7A		GO:0061724	lipophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy|Recruiting autophagy factors to lipid droplets	ADRB2;AUP1;RAB7A;RAB7B;UBE2G2	GO:0061724 lipophagy	1
RAB7B		GO:0061724	lipophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy|Recruiting autophagy factors to lipid droplets	ADRB2;AUP1;RAB7A;RAB7B;UBE2G2		1
RAB8B		GO:0031201	SNARE complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	RAB8B;SNAP29;STX17;STX7;YKT6		1
RABGEF1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagosome formation for selective autophagy|Mitophagy	CALCOCO2;RABGEF1		1
RAC1		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of LAMP2A multimerization	AMBRA1;GFAP;MT-RNR2;PSME1;TP53		1
RACK1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
RACK1		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
RACK1		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4		1
RACK1		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
RAD18		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SAP;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / SAP|UBZ4-type ZnF	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RAD23A		GO:0043130	ubiquitin binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0043130 ubiquitin binding	1
RAD23A		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B	GO:0070628 proteasome binding	2
RAD23B		GO:0043130	ubiquitin binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0043130 ubiquitin binding	1
RAD23B		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B	GO:0070628 proteasome binding	2
RAD50		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-C complex|MRN subcomplex /  ATPase	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
RAD51AP1		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA binding|UIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
RAE1		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
RAE1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
RAE1		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S export adapter	AATF;IMP3;NOP56;UTP4		1
RAG1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|RAG complex	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RAN		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006913 nucleocytoplasmic transport	1
RAN		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006611 protein export from nucleus	1
RANBP10		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / CRA, LisH, SPRY	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
RANBP17		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006913 nucleocytoplasmic transport	2
RANBP17		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
RANBP2		GO:0003755	peptidyl-prolyl cis-trans isomerase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases;Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	Cytonuclear proteostasis|Folding enzyme|Peptidyl-prolyl isomerases|Cyclophilin type	AIP;AIPL1;CWC27;FKBP1A;FKBP1B;FKBP3;NKTR;PPIA;PPIAL4A;PPIAL4C		2
RANBP2		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
RANBP2		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006913 nucleocytoplasmic transport	1
RANBP2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex;Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	2
RANBP3		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006611 protein export from nucleus	1
RANBP3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus	1
RANBP3L		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006611 protein export from nucleus	1
RANBP3L		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus	1
RANBP6		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
RANBP6		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
RANBP9		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / CRA, LisH, SPRY	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
RANGAP1		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0051168 nuclear export	1
RANGAP1		GO:0015031	protein transport	supported_by_goa_regulation	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0046826 negative regulation of protein export from nucleus	1
RAPSN		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|TPR	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RARA		GO:1904715	negative regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Extralysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Represses transcription of CMA components	BMAL1;RAB11A;RARA		1
RARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
RARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
RB1CC1		GO:1990316	Atg1/ULK1 kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:1990316 Atg1/ULK1 kinase complex	1
RBBP4		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
RBBP6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / other	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / other	MID1;MID2;RBBP6;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RBBP7		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
RBBP8		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-C complex|DNA endonuclease	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
RBCK1		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC|catalytic / RBR	RBCK1;RNF31;SHARPIN	GO:0071797 LUBAC complex	2
RBCK1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / LUBAC complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|UBL, RanBP2-type ZnF;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / LUBAC|RanBP2-type ZnF;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / LUBAC complex	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31;SHARPIN	GO:0061630 ubiquitin protein ligase activity	3
RBFA		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA chaperone	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0180026 mitochondrial small ribosomal subunit assembly	1
RBM10		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|RanBP2-type ZnF	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
RBM44		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|UBA-like (other)	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
RBM5		GO:0048024	regulation of mRNA splicing, via spliceosome	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|RanBP2-type ZnF	RBM10;RBM44;RBM5;RBM6;ZRANB2	GO:0000381 regulation of alternative mRNA splicing, via spliceosome	1
RBM6		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|RanBP2-type ZnF	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
RBX1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBX RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBX RING	RBX1;RNF7	GO:0061630 ubiquitin protein ligase activity	1
RC3H1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Roquin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RC3H2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Roquin|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RCBTB1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|RCC1	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
RCBTB2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|RCC1	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
RCC1		GO:0006913	nucleocytoplasmic transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2		1
RCC1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2		1
RCC1L		GO:0006913	nucleocytoplasmic transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2		1
RCC1L		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2		1
RCC1L		GO:0061668	mitochondrial ribosome assembly	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA chaperone	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0061668 mitochondrial ribosome assembly	1
RCHY1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RCL1		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|RCL1-BMS1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
RCL1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|RCL1-BMS1 complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
REL		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
REL		GO:0006954	inflammatory response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Inflammatory response	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0006954 inflammatory response	1
REL		GO:0071159	NF-kappaB complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0005634 nucleus	2
RELA		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
RELA		GO:0006954	inflammatory response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Inflammatory response	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0006954 inflammatory response	1
RELA		GO:0071159	NF-kappaB complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0071159 NF-kappaB complex	2
RELB		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
RELB		GO:0006954	inflammatory response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Inflammatory response	PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0006954 inflammatory response	1
RELB		GO:0071159	NF-kappaB complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;pn_regulation.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	Autophagy-Lysosome Pathway|Autophagy gene expression|NFkB transcriptional program|Component of NFkB transcription factor;PN regulation|Transcription factor|Inflammatory response|Transcription of xenobiotic response genes|NFkB complex component	NFKB1;NFKB2;REL;RELA;RELB	GO:0005634 nucleus;GO:0032991 protein-containing complex	2
RETREG1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
RETREG2		GO:0061709	reticulophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62		1
RETREG3		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
REV1		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|dCTP transferase|UBM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
REXO2		GO:0006364	rRNA processing	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	REXO2;ZFP42	GO:0006139 nucleobase-containing compound metabolic process;GO:0016070 RNA metabolic process	1
REXO2		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	AATF;IMP3;NOP56;UTP4		1
RFC1		GO:0006260	DNA replication	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication|DNA polymerase clamp loader|tandem MIU	RFC1;WRNIP1;ZRANB3	GO:0006260 DNA replication	1
RFFL		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SAP	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL Group 1	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL Group 1	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL Group 1	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL4A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL Group 2	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL4AL1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL Group 2	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFPL4B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|RFPL other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RFWD3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|RFWD|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RGPD1		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD2		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD3		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD4		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD5		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD5		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD6		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD6		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RGPD8		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	RAN;RANBP2;RANGAP1;RGPD1;RGPD2	GO:0006607 NLS-bearing protein import into nucleus;GO:0051168 nuclear export	1
RGPD8		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport, RAN system	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006607 NLS-bearing protein import into nucleus	1
RHBDD1		GO:0004252	serine-type endopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	RHBDD1;RHBDD2;RHBDL3	GO:0004252 serine-type endopeptidase activity	1
RHBDD1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
RHBDD2		GO:0004252	serine-type endopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	RHBDD1;RHBDD2;RHBDL3	GO:0004252 serine-type endopeptidase activity	1
RHBDD2		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
RHBDL3		GO:0004252	serine-type endopeptidase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	RHBDD1;RHBDD2;RHBDL3	GO:0004252 serine-type endopeptidase activity	1
RHBDL3		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|Intramembrane protease, cleaves unstable membrane proteins, transfers to ERAD	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP		2
RHOBTB1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|small GTPase	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
RHOBTB2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|small GTPase	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
RHOBTB3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|small GTPase	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
RICTOR		GO:0031932	TORC2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR	GO:0031932 TORC2 complex	1
RICTOR		GO:1904715	negative regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy inhibitor|Modulator of LAMP2A multimerization	AKT1;CTSA;RICTOR		1
RICTOR		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|non-canonical	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:0060090 molecular adaptor activity;GO:0140767 enzyme-substrate adaptor activity	1
RILP		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|Recruitment of dynein-dynactin motor complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|Recruitment of dynein-dynactin motor complex	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3		3
RING1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RIOK1		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
RIOK1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
RIOK2		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
RIOK2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
RIOK3		GO:0030688	preribosome, small subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0030688 preribosome, small subunit precursor	1
RIOK3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA	1
RLIM		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RMND5A		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|catalytic / RING, CRA, LisH	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
RMND5B		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|catalytic / RING, CRA, LisH	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0034657 GID complex	1
RMRP		GO:0006364	rRNA processing	no_local_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP		1
RMRP		GO:0042254	ribosome biogenesis	no_local_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4		1
RNF10		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF103		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
RNF103		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF11		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF111		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SUMO binding domain;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / SUMO binding domain|SIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF112		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|P-loop NTP hydrolase & transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF113A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF113B		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	1
RNF114		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAC-1;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRAC-1|UIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF115		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Praja;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / Praja|idiosyncratic Ub binding / zinc ribbon	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF121		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF122		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, Golgi	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF123		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|KPC complex|catalytic / RING, SPRY	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
RNF123		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF125		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAC-1;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRAC-1|UIM;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases|RING|TRAC-1	AMFR;ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;RNF125;RNF31;SYVN1;TRIM36;TRIM46;TRIM9;UBE4B	GO:0061630 ubiquitin protein ligase activity	3
RNF126		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Praja;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / Praja|idiosyncratic Ub binding / zinc ribbon	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF128		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF13		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF130		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF133		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF135		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF138		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAC-1;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRAC-1|UIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF139		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
RNF139		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF14		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
RNF14		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GCN1;RNF14;RNF25	GO:0016567 protein ubiquitination	1
RNF14		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|RWD;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / with UBD|RWD	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
RNF141		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	1
RNF144A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|transmembrane	ANKIB1;ARIH1;ARIH2;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	1
RNF144B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|transmembrane	ANKIB1;ARIH1;ARIH2;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	1
RNF145		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
RNF145		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF146		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Deltex|WWE	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF148		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF149		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF150		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF151		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SIAH / SINA	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF152		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|lysosome	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF157		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF166		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAC-1;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRAC-1|UIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF166		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Xenophagy|Catalyzes K33-linked ubiquitination of p62	LRSAM1;PHF23;RNF166		1
RNF167		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF168		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|MIU	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF169		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|MIU	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF17		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF170		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|RNF170 / ERLIN complex|catalytic / RING, transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
RNF170		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
RNF170		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF175		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF180		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, nuclear envelope	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF181		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF182		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|cytoplasm	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF183		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, Golgi, lysosome	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF185		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|membralin complex|catalytic / RING, transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
RNF185		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1		1
RNF185		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
RNF185		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, mitochondria	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF186		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF187		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|FHA	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF19A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|transmembrane	ANKIB1;ARIH1;ARIH2;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	1
RNF19B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|transmembrane	ANKIB1;ARIH1;ARIH2;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	1
RNF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Polycomb|RAWUL;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / RAWUL / polycomb	BMI1;MID1;MID2;PCGF1;PCGF2;RING1;RNF2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF20		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|RNF20/40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF207		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF208		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF212		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF212B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF213		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RZ	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RZ|dynein-like motor	RNF213;ZNFX1	GO:0061630 ubiquitin protein ligase activity	1
RNF214		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|TTC3/DZIP3;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|UBA-like (other)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	2
RNF215		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF216		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / with UBD|SIM	ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	2
RNF217		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|transmembrane	ANKIB1;ARIH1;ARIH2;RBCK1;RNF31	GO:0061630 ubiquitin protein ligase activity	1
RNF220		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|UBZ (RNF220)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF222		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF223		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF224		GO:0061630	ubiquitin protein ligase activity	no_local_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF225		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF227		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF228		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF24		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|Golgi	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF25		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
RNF25		GO:0016567	protein ubiquitination	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	Translation|Cytosolic translation|Ribosome-associated QC|ubiquitination of eEF1A on stalled ribosomes	GCN1;RNF14;RNF25	GO:0016567 protein ubiquitination	1
RNF25		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|RWD;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|RWD	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF26		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF31		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC|catalytic / RBR	RBCK1;RNF31;SHARPIN	GO:0071797 LUBAC complex	2
RNF31		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBR|PUB, RanBP2-type ZnF, UBA;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RBR / PUB|UBA, RanBP2-type ZnF;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases|RBR|PUB, UBA	AMFR;ANKIB1;ARIH1;ARIH2;ASB2;FBXW4;FBXW7;FBXW8;PML;RBCK1;RNF125;RNF31;SYVN1;UBE4B	GO:0061630 ubiquitin protein ligase activity	3
RNF32		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RNF34		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SAP	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF38		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF39		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SUMO binding domain;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / SUMO binding domain|SIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF40		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|RNF20/40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF41		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
RNF41		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SIAH / SINA	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF43		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, nuclear envelope, cell membrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF44		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF5		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
RNF5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER, mitochondria, cell membrane	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNF5		GO:2000785	regulation of autophagosome assembly	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Modulation of ATG4 activity	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, upstream|Preparation of ATG8 homologs for lipidation|Modulation of ATG4 activity	RNF5		1
RNF6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNF7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBX RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RBX RING	RBX1;RNF7	GO:0061630 ubiquitin protein ligase activity	1
RNF8		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|FHA	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RNFT1		GO:0036503	ERAD pathway	supported_by_goa_regulation	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:1904294 positive regulation of ERAD pathway	2
RNFT1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
RNFT2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
RPAP3		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and RPAP3-like C-terminal domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
RPF2		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
RPF2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0000027 ribosomal large subunit assembly;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000470 maturation of LSU-rRNA;GO:0006364 rRNA processing;GO:0042273 ribosomal large subunit biogenesis	1
RPL10		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL10		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL10A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL10A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL10L		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL10L		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL11		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL11		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL12		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL12		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL13		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL13		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL13A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL13A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL14		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL14		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL15		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL15		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL17		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL17		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL18		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL18		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL18A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL18A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL19		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL19		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL21		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL21		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL22		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL22		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL23		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL23		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL23A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL23A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL24		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL24		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL26		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL26		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL26L1		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL26L1		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL27		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL27		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL27A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL27A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL28		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL28		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL29		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL29		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL3		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL3		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL30		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL30		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL31		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL31		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL32		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL32		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL34		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL34		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL35		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL35		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL35A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL35A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL36		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL36		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL36A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL36A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL36AL		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL36AL		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL37		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL37		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL37A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL37A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL38		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL38		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL39		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL39		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL39L		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL39L		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL3L		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL3L		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL4		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL4		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL41		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL41		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL5		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL5		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL6		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL6		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL7		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL7		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL7A		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL7A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL7L1		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL7L1		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPL8		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL8		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPL9		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPL9		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPLP0		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPLP0		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPLP1		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPLP1		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPLP2		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
RPLP2		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022625 cytosolic large ribosomal subunit	2
RPN1		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
RPN1		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
RPN2		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
RPN2		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
RPS10		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS10		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS11		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS11		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS12		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS12		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS13		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS13		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS14		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS14		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS15		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS15		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS15A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS15A		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS16		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS16		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS17		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS17		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS18		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS18		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS19		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS19		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS2		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS2		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS20		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS20		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS21		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS21		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS23		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS23		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS24		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS24		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS25		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS25		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS26		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS26		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS27		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS27		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS27A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS27A		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS27L		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	2
RPS27L		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS28		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS28		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS29		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS29		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS3		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS3		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS3A		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS3A		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS4X		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS4X		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS4Y1		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	2
RPS4Y1		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS4Y2		GO:0022626	cytosolic ribosome	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	2
RPS4Y2		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS5		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS5		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS6		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS6		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS7		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS7		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS8		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS8		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPS9		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPS9		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPSA		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
RPSA		GO:0022627	cytosolic small ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|40S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022627 cytosolic small ribosomal subunit	1
RPTOR		GO:0031931	TORC1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR	GO:0031931 TORC1 complex	1
RPUSD4		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA pseudouridylation	MRM1;MRM2;MRM3;RPUSD4;TRMT61B	GO:0000154 rRNA modification	1
RPUSD4		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA pseudouridylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
RPUSD4		GO:0120159	rRNA pseudouridine synthase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA pseudouridylation	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA pseudouridylation	RPUSD4	GO:0009982 pseudouridine synthase activity	1
RRP12		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
RRP12		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4		1
RRP36		GO:0032040	small-subunit processome	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0005730 nucleolus	1
RRP36		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis	1
RRP7A		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
RRP7A		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-C complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
RRP8		GO:0000154	rRNA modification	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3		1
RRP8		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4		1
RRP9		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
RRP9		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
RRS1		GO:0030687	preribosome, large subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:0030687 preribosome, large subunit precursor	1
RRS1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
RSF1		GO:0006338	chromatin remodeling	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling;Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling|idiosyncratic Ub binding / other	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling|idiosyncratic Ub binding / other	CHD3;RSF1;SMARCAD1	GO:0006338 chromatin remodeling	2
RSL24D1		GO:0000027	ribosomal large subunit assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	BCCIP;RSL24D1	GO:0042273 ribosomal large subunit biogenesis	1
RSL24D1		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|60S maturation	AATF;IMP3;NOP56;UTP4	GO:0042273 ribosomal large subunit biogenesis	1
RSPRY1		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SPRY but not TRIM|Armadillo	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0004842 ubiquitin-protein transferase activity	1
RTN3		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
RUBCN		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG		1
RUBCNL		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG		1
RUFY1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
RUFY3		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3;RUFY4		3
RUFY4		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging	ARL8A;ARL8B;MAP1LC3B;RILP;RUFY3;RUFY4		3
RUVBL1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
RUVBL2		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
S100A1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
SACS		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	Cytonuclear proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0030544 Hsp70 protein binding	1
SACS		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|UBL only	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B	GO:0070628 proteasome binding	1
SAE1		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of SUMO	Ubiquitin Proteasome System|E1 activating enzymes|activation of SUMO	SAE1;UBA2	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
SAMM50		GO:0005741	mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	Mitochondrial proteostasis|Membrane protein folding|Sorting and assembly machinery outer membrane	MTX1;MTX2;MTX3;SAMM50	GO:0005741 mitochondrial outer membrane	1
SAMTOR		GO:1990130	GATOR1 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex modulator	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR1 complex modulator	SAMTOR		1
SANBR		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK, variant|other	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
SAR1A		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SAR1A		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SAR1A		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SAR1B		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SAR1B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport;GO:0042953 lipoprotein transport	1
SAR1B		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SAR1B		GO:0061700	GATOR2 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	SAR1B;SESN1;SESN2;SESN3		1
SARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
SARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
SART1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|other	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91		1
SBDS		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
SBDS		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
SCAF11		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
SCYL1		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	COPA;COPB1;COPB2;COPE;COPG1	GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	1
SCYL1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SCYL1		GO:0030126	COPI vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	GORAB;SCYL1;SCYL3	GO:0030126 COPI vesicle coat	1
SCYL3		GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	COPA;COPB1;COPB2;COPE;COPG1		1
SCYL3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SCYL3		GO:0030126	COPI vesicle coat	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	ER proteostasis|Protein transport|ER-Golgi trafficking|Retrograde transport|COPI scaffolding in the Golgi	GORAB;SCYL1;SCYL3	GO:0005737 cytoplasm;GO:0005794 Golgi apparatus	1
SDE2		GO:0006281	DNA repair	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|nucleic acid processes|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|nucleic acid processes|DNA repair	SDE2		1
SEC11A		GO:0005787	signal peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER signal peptidase	ER proteostasis|Protein transport|ER signal peptidase	SEC11A;SEC11C;SPCS1;SPCS2;SPCS3	GO:0005787 signal peptidase complex	1
SEC11A		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER signal peptidase	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SEC11C		GO:0005787	signal peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER signal peptidase	ER proteostasis|Protein transport|ER signal peptidase	SEC11A;SEC11C;SPCS1;SPCS2;SPCS3	GO:0005787 signal peptidase complex	1
SEC11C		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER signal peptidase	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SEC13		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml;ubiquitin_proteasome_system.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit|GATOR2 complex|SUMO binding / WD40	GLE1;NUP153;NUP214;NUP88;RAE1;RANBP2;SEC13;SEH1L	GO:0005643 nuclear pore	2
SEC13		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC13		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml;nuclear_proteostasis.yaml	ER proteostasis|Protein transport;Nuclear proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component;Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2;SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport;GO:0032527 protein exit from endoplasmic reticulum	2
SEC13		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC13		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	MIOS;SEC13;SEH1L;WDR24;WDR59	GO:0061700 GATOR2 complex	1
SEC23A		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC23A		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC23A		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC23B		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC23B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC23B		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC23IP		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC23IP		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC23IP		GO:0030127	COPII vesicle coat	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0005737 cytoplasm;GO:0012507 ER to Golgi transport vesicle membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle	2
SEC24A		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC24A		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC24A		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC24B		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC24B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC24B		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC24C		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC24C		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC24C		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC24D		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC24D		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SEC24D		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC31A		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC31A		GO:0015031	protein transport	supported_by_goa_regulation	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0070863 positive regulation of protein exit from endoplasmic reticulum	1
SEC31A		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC31B		GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport	1
SEC31B		GO:0015031	protein transport	supported_by_goa_regulation	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0070863 positive regulation of protein exit from endoplasmic reticulum	1
SEC31B		GO:0030127	COPII vesicle coat	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ER membrane input|COPII vesicle component;ER proteostasis|Protein transport|ER-Golgi trafficking|Anterograde transport|COPII vesicle component	SEC13;SEC23A;SEC23B;SEC31A;SEC31B	GO:0030127 COPII vesicle coat	2
SEC61A1		GO:0005784	Sec61 translocon complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005784 Sec61 translocon complex	1
SEC61A1		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0015031 protein transport	1
SEC61A2		GO:0005784	Sec61 translocon complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005784 Sec61 translocon complex	1
SEC61A2		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0015031 protein transport	1
SEC61B		GO:0005784	Sec61 translocon complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005784 Sec61 translocon complex	1
SEC61B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation;GO:0006886 intracellular protein transport;GO:0030970 retrograde protein transport, ER to cytosol;GO:0031204 post-translational protein targeting to membrane, translocation	1
SEC61G		GO:0005784	Sec61 translocon complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005784 Sec61 translocon complex	1
SEC61G		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0015031 protein transport	1
SEC62		GO:0005784	Sec61 translocon complex	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005791 rough endoplasmic reticulum;GO:0016020 membrane	1
SEC62		GO:0015031	protein transport	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0015031 protein transport	1
SEC62		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
SEC63		GO:0005784	Sec61 translocon complex	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SEC61 channel complex component	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane	1
SEC63		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0031204 post-translational protein targeting to membrane, translocation	1
SEC63		GO:0030544	Hsp70 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone	DNAJA3;DNAJB1;DNAJB6;HSCB	GO:0005515 protein binding	1
SECISBP2		GO:0003746	translation elongation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	Translation|Cytosolic translation|Translation elongation|assorted elongation factors	EEF1A1;EEF1A2;EEF2;EEF2K;EEF2KMT		1
SEH1L		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml;ubiquitin_proteasome_system.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit	Nuclear proteostasis|Protein transport|Nuclear pore complex;Ubiquitin Proteasome System|Ubiquitin and UBL binding|nuclear pore complex subunit|GATOR2 complex|SUMO binding / WD40	GLE1;NUP153;NUP214;NUP88;RAE1;RANBP2;SEC13;SEH1L	GO:0005643 nuclear pore	2
SEH1L		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2		1
SEH1L		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	MIOS;SEC13;SEH1L;WDR24;WDR59	GO:0061700 GATOR2 complex	1
SEL1L		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
SEL1L2		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
SELENOF		GO:0006487	protein N-linked glycosylation	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Re-glucosylation	DAD1;DDOST;MAGT1;OSTC;RPN1		1
SELENOS		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
SEM1		GO:0005838	proteasome regulatory particle	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|SEM1	PSMC1;PSMC2;PSMC3;PSMC4;PSMC5	GO:0008541 proteasome regulatory particle, lid subcomplex	1
SEM1		GO:0008541	proteasome regulatory particle, lid subcomplex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase	Ubiquitin Proteasome System|Proteasome and associated proteins|proteasome regulatory particle subunit|lid, nonATPase|SEM1	PSMD11;PSMD14;PSMD3;PSMD6;PSMD7	GO:0008541 proteasome regulatory particle, lid subcomplex	1
SENP8		GO:0019784	deNEDDylase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|SENP|deNEDDylase, NEDD8 processing	Ubiquitin Proteasome System|DUBs and UBL demodifiers|SENP|deNEDDylase, NEDD8 processing	SENP8	GO:0019784 deNEDDylase activity	1
SEPSECS		GO:0004812	aminoacyl-tRNA ligase activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA		1
SERP1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel accessory protein	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SERP2		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel accessory protein	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SERPINH1		GO:0032964	collagen biosynthetic process	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	ER proteostasis|Maturation and folding of specific substrates|ER collagen processing and folding	P4HA1;P4HA2;P4HA3;P4HB;PLOD1		1
SESN1		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	SAR1B;SESN1;SESN2;SESN3	GO:0061700 GATOR2 complex	1
SESN2		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	SAR1B;SESN1;SESN2;SESN3	GO:0061700 GATOR2 complex	1
SESN3		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex modulator	SAR1B;SESN1;SESN2;SESN3	GO:0061700 GATOR2 complex	1
SET		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
SGSH		GO:0016250	N-sulfoglucosamine sulfohydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparin sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal heparin sulfatase	SGSH	GO:0016250 N-sulfoglucosamine sulfohydrolase activity	1
SGTA		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane	1
SGTA		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SGTA		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and SGTA dimerization domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
SGTB		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane	1
SGTB		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SGTB		GO:0031072	heat shock protein binding	entailed_by_goa_closure	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and SGTA dimerization domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0030544 Hsp70 protein binding	1
SH3GLB1		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG	GO:0016020 membrane;GO:0032991 protein-containing complex	1
SH3RF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SH3	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SH3RF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SH3	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SH3RF3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SH3	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SHARPIN		GO:0000151	ubiquitin ligase complex	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RBR complex|LUBAC|noncatalytic / UBL;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase complex component|LUBAC|RanBP2-type ZnF	ANAPC11;ANAPC2;FANCL;KCMF1;RBCK1;RNF31;SHARPIN	GO:0071797 LUBAC complex	3
SHARPIN		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / LUBAC complex	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RBR / LUBAC complex	RBCK1;SHARPIN	GO:0004842 ubiquitin-protein transferase activity	1
SHKBP1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|WD40	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
SHPRH		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|second enzymatic function|helicase	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SIAE		GO:0001681	sialate O-acetylesterase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialic acid deacetylase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal carbohydrate catabolism|Lysosomal sialic acid deacetylase	SIAE	GO:0001681 sialate O-acetylesterase activity	1
SIAH1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
SIAH1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SIAH / SINA|SIA TRAF-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SIAH2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SIAH / SINA|SIA TRAF-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
SIL1		GO:0000774	adenyl-nucleotide exchange factor activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	ER proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor	ER proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange factor|HSPBP1 subtype	BAG1;GRPEL1;GRPEL2;HSPBP1	GO:0000774 adenyl-nucleotide exchange factor activity	1
SKP1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cullin adaptor|Skp1	DDB1;SKP1	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
SKP2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|LRR	FBXL2;FBXL3;FBXL4;FBXL5;SKP2	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
SLC25A4		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901526 positive regulation of mitophagy	1
SLC25A5		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901526 positive regulation of mitophagy	1
SLX4		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA endonuclease cofactor|UIM, UBZ4-type ZnF, SIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
SMARCAD1		GO:0006338	chromatin remodeling	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling	Ubiquitin Proteasome System|Ubiquitin and UBL binding|other DNA dependent processes|chromatin remodeling|CUE	CHD3;RSF1;SMARCAD1	GO:0006338 chromatin remodeling	1
SMN1		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|SIM	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
SMN2		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|SIM	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
SMPD1		GO:0061750	acid sphingomyelin phosphodiesterase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Converts sphingomyelin to ceramide	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Converts sphingomyelin to ceramide	SMPD1	GO:0061750 acid sphingomyelin phosphodiesterase activity	1
SMURF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination & NEDDylation	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
SMURF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination & NEDDylation	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
SMYD4		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and methyltransferase domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
SNAP29		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	RAB8B;SNAP29;STX17;STX7;VAMP7;YKT6	GO:0031201 SNARE complex	2
SNAPIN		GO:0099078	BORC complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|BORC complex component	BLOC1S1;BLOC1S2;BORCS5;KXD1;SNAPIN	GO:0099078 BORC complex	1
SNCAIP		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
SNORD3A		GO:0032040	small-subunit processome	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75		1
SNORD3A		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA	1
SNU13		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
SNU13		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|U3 snoRNP complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
SNUPN		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	HEATR3;HIKESHI;KPNA2;KPNB1;SNUPN;XPO1	GO:0006404 RNA import into nucleus;GO:0006606 protein import into nucleus;GO:0061015 snRNA import into nucleus;GO:0061608 nuclear import signal receptor activity	2
SNUPN		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Non-importin transport receptor	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
SOX2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|SOX2 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|SOX2 transcriptional program|Transcription factor	SOX2	GO:0003700 DNA-binding transcription factor activity	1
SPAG1		GO:0031072	heat shock protein binding	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and RPAP3-like C-terminal domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4		1
SPCS1		GO:0005787	signal peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER signal peptidase	ER proteostasis|Protein transport|ER signal peptidase	SEC11A;SEC11C;SPCS1;SPCS2;SPCS3	GO:0005787 signal peptidase complex	1
SPCS1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER signal peptidase	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SPCS2		GO:0005787	signal peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER signal peptidase	ER proteostasis|Protein transport|ER signal peptidase	SEC11A;SEC11C;SPCS1;SPCS2;SPCS3	GO:0005787 signal peptidase complex	1
SPCS2		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER signal peptidase	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SPCS3		GO:0005787	signal peptidase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|ER signal peptidase	ER proteostasis|Protein transport|ER signal peptidase	SEC11A;SEC11C;SPCS1;SPCS2;SPCS3	GO:0005787 signal peptidase complex	1
SPCS3		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER signal peptidase	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SPG7		GO:0005759	mitochondrial matrix	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005739 mitochondrion	1
SPG7		GO:0035694	mitochondrial protein catabolic process	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0007005 mitochondrion organization	1
SPHK2		GO:0008481	sphingosine kinase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Phosphorylates sphingomyelin	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal lipid catabolism|Lysosomal sphingomyelin/ceramide metabolism|Phosphorylates sphingomyelin	SPHK2	GO:0008481 sphingosine kinase activity	1
SPNS1		GO:0007041	lysosomal transport	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagic lysosome reformation|Efflux of autophagy products	Autophagy-Lysosome Pathway|Autophagic lysosome reformation|Efflux of autophagy products	SPNS1		1
SPOP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|MATH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
SPOPL		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB-BACK|MATH	ENC1;GAN;IPP;KBTBD2;KBTBD3		1
SPTY2D1		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
SQSTM1		GO:0000423	mitophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1	GO:0000423 mitophagy	1
SQSTM1		GO:0000425	pexophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Pexophagy	NBR1;PJVK;SQSTM1	GO:0000425 pexophagy	1
SQSTM1		GO:0035973	aggrephagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	MAP1S;NBR1;OPTN;SQSTM1;TOLLIP	GO:0035973 aggrephagy	1
SQSTM1		GO:0070628	proteasome binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|PB1|UBA	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B	GO:0044877 protein-containing complex binding	1
SQSTM1		GO:0098792	xenophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	CALCOCO2;OPTN;SQSTM1;TAX1BP1;TRIM5	GO:0006914 autophagy;GO:0016236 macroautophagy	1
SQSTM1		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	NBR1;SQSTM1;TRIM17	GO:0006914 autophagy;GO:0016236 macroautophagy;GO:0030674 protein-macromolecule adaptor activity	1
SREBF1		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901524 regulation of mitophagy	1
SREBF2		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901524 regulation of mitophagy	1
SREBF2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|SREBF2 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|SREBF2 transcriptional program|Transcription factor	SREBF2	GO:0003700 DNA-binding transcription factor activity	1
SRP14		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP14		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation	1
SRP19		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP19		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SRP54		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP54		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation	1
SRP68		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP68		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SRP72		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP72		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SRP9		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Signal recognition particle component	ER proteostasis|Protein transport|Signal recognition particle component	SRP14;SRP19;SRP54;SRP68;SRP9	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRP9		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Signal recognition particle component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SRPRA		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SRP receptor subunit	ER proteostasis|Protein transport|SRP receptor subunit	SRPRA;SRPRB	GO:0006614 SRP-dependent cotranslational protein targeting to membrane	1
SRPRA		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SRP receptor subunit	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
SRPRB		GO:0006614	SRP-dependent cotranslational protein targeting to membrane	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|SRP receptor subunit	ER proteostasis|Protein transport|SRP receptor subunit	SRPRA;SRPRB	GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	1
SRPRB		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SRP receptor subunit	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
SSR1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|TRAP complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0031204 post-translational protein targeting to membrane, translocation	1
SSR2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|TRAP complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0031204 post-translational protein targeting to membrane, translocation	1
SSR3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|TRAP complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0031204 post-translational protein targeting to membrane, translocation	1
SSR4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|TRAP complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0031204 post-translational protein targeting to membrane, translocation	1
SSRP1		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
ST13		GO:0030544	Hsp70 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange inhibitor	Cytonuclear proteostasis|Chaperone|HSP70 system|HSP70 nucleotide exchange inhibitor|TPR domain subtype	ST13	GO:0030544 Hsp70 protein binding	1
ST13		GO:0061684	chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8		1
ST13		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	HSP90AA1;HSP90AB1;ST13;STIP1;STUB1		1
STAMBP		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|USP dimerization domain	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|USP dimerization domain	STAMBP;STAMBPL1	GO:0140492 metal-dependent deubiquitinase activity	1
STAMBPL1		GO:0140492	metal-dependent deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|USP dimerization domain	Ubiquitin Proteasome System|DUBs and UBL demodifiers|JAMM / MPN|USP dimerization domain	STAMBP;STAMBPL1	GO:0140492 metal-dependent deubiquitinase activity	1
STAT3		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|STAT3 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|STAT3 transcriptional program|Transcription factor	STAT3	GO:0003700 DNA-binding transcription factor activity	1
STAT6		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|STAT6 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|STAT6 transcriptional program|Transcription factor	STAT6	GO:0003700 DNA-binding transcription factor activity	1
STBD1		GO:0061723	glycophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Glycophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Glycophagy	STBD1	GO:0061723 glycophagy	1
STIP1		GO:0031072	heat shock protein binding	entailed_by_goa_closure	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and STI/HOP domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0051879 Hsp90 protein binding	1
STIP1		GO:0061684	chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8		1
STIP1		GO:0061738	late endosomal microautophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	Autophagy-Lysosome Pathway|Microautophagy|Endosomal microautophagy	DNAJB1;HSPA8;STIP1		1
STIP1		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	HSP90AA1;HSP90AB1;ST13;STIP1;STUB1		1
STS		GO:0008484	sulfuric ester hydrolase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal sulfatase	ARSA;ARSB;ARSD;ARSG;GALNS	GO:0008484 sulfuric ester hydrolase activity	1
STT3A		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
STT3A		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
STT3B		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
STT3B		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
STUB1		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic UBOX complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic UBOX complex|STUB1/CHIC2 complex|catalytic / UBOX / TPR	CHIC2;STUB1	GO:0000151 ubiquitin ligase complex	1
STUB1		GO:0031072	heat shock protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0031072 heat shock protein binding	1
STUB1		GO:0035973	aggrephagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Chaperone assisted selective autophagy|CASA complex component	BAG3;HSPA8;HSPB8;STUB1		1
STUB1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml;ubiquitin_proteasome_system.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|TPR	LONRF3;PRPF19;STUB1;TTC3;UBE4A;UBOX5;WDSUB1;WDTC1	GO:0061630 ubiquitin protein ligase activity	2
STUB1		GO:0061684	chaperone-mediated autophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	CLU;DNAJB1;HSP90AA1;HSP90AB1;HSPA8	GO:0061684 chaperone-mediated autophagy	1
STUB1		GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Effectors of chaperone-mediated autophagy|Substrate selection	HSP90AA1;HSP90AB1;ST13;STIP1;STUB1	GO:0030163 protein catabolic process;GO:0061684 chaperone-mediated autophagy	1
STX12		GO:0000045	autophagosome assembly	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex activity modulator;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|Localization of the ESCRT-III complex	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000045 autophagosome assembly	2
STX12		GO:0000815	ESCRT III complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0010008 endosome membrane;GO:0012505 endomembrane system;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle;GO:0031982 vesicle	1
STX17		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	RAB8B;SNAP29;STX17;STX7;VAMP7;YKT6	GO:0031201 SNARE complex	2
STX6		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	STX6;VAMP3;VTI1B	GO:0031201 SNARE complex	1
STX7		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	RAB8B;SNAP29;STX17;STX7;YKT6	GO:0031201 SNARE complex	1
STX7		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
STX8		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
SUGT1		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|TPR and CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
SUPT16H		GO:0140713	histone chaperone activity	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0000511 H2A-H2B histone complex chaperone activity	1
SUPT6H		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
SVIP		GO:0036503	ERAD pathway	supported_by_goa_regulation	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	DERL1;DERL2;DERL3;ERLIN1;ERLIN2;HERPUD1;JKAMP;SVIP;SYVN1;TMUB1	GO:1904293 negative regulation of ERAD pathway	2
SYVN1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
SYVN1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|with transmembrane domain|ER;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases|RING|VBM & transmembrane	AMFR;MID1;MID2;RNF125;RNF31;SYVN1;TRIM36;TRIM46;TRIM9;UBE4B	GO:0061630 ubiquitin protein ligase activity	2
SZT2		GO:0140007	KICSTOR complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|KICSTOR complex component	ITFG2;KICS2;KPTN;SZT2	GO:0140007 KICSTOR complex	1
TANK		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1		1
TARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
TARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
TARS3		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
TAX1BP1		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
TAX1BP1		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	ARL8A;ARL8B;CALCOCO2;MAP1LC3B;MYO6;RILP;RUFY3;TAX1BP1;TOM1		2
TAX1BP1		GO:0098792	xenophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	CALCOCO2;OPTN;SQSTM1;TAX1BP1;TRIM5		1
TBC1D15		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
TBC1D17		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
TBCA		GO:0007023	post-chaperonin tubulin folding pathway	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	TBCA;TBCB;TBCC;TBCD;TBCE	GO:0007023 post-chaperonin tubulin folding pathway	1
TBCB		GO:0007023	post-chaperonin tubulin folding pathway	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	TBCA;TBCB;TBCC;TBCD;TBCE	GO:0007023 post-chaperonin tubulin folding pathway	1
TBCC		GO:0007023	post-chaperonin tubulin folding pathway	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	TBCA;TBCB;TBCC;TBCD;TBCE	GO:0007023 post-chaperonin tubulin folding pathway	1
TBCD		GO:0007023	post-chaperonin tubulin folding pathway	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	TBCA;TBCB;TBCC;TBCD;TBCE	GO:0007023 post-chaperonin tubulin folding pathway	1
TBCE		GO:0007023	post-chaperonin tubulin folding pathway	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC cochaperone|Tubulin folding	TBCA;TBCB;TBCC;TBCD;TBCE	GO:0007023 post-chaperonin tubulin folding pathway	1
TBK1		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Autophagy receptor regulation|Mitophagy	BNIP1;MARCHF5;RNF185;TANK;TBK1	GO:0016236 macroautophagy	1
TBL3		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
TBL3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
TBL3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate adaptor|AHR / ARNT / TBL3 complex|WD40	AHR;ARNT;COP1;DCAF13;DCAF7		1
TCF25		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|other RQC processes	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
TCF7L2		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TCF7L2 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TCF7L2 transcriptional program|Transcription factor	TCF7L2	GO:0003700 DNA-binding transcription factor activity	1
TCIRG1		GO:0007042	lysosomal lumen acidification	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0007042 lysosomal lumen acidification	1
TCIRG1		GO:0033179	proton-transporting V-type ATPase, V0 domain	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0033179 proton-transporting V-type ATPase, V0 domain	1
TCIRG1		GO:0046610	lysosomal proton-transporting V-type ATPase, V0 domain	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1	GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0016020 membrane;GO:0016471 vacuolar proton-transporting V-type ATPase complex;GO:0033179 proton-transporting V-type ATPase, V0 domain	1
TCP1		GO:0005832	chaperonin-containing T-complex	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	Cytonuclear proteostasis|Chaperone|CCT/TRiC system|CCT/TRiC subunit	CCT2;CCT3;CCT4;CCT5;TCP1	GO:0005832 chaperonin-containing T-complex	1
TDG		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA glycosylase|SIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006284 base-excision repair;GO:0006285 base-excision repair, AP site formation;GO:0045008 depyrimidination	1
TDP2		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|5'-tyrosyl DNA phosphodiesterase|UBA-like (TDP2)	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006302 double-strand break repair	1
TELO2		GO:0031931	TORC1 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR		1
TELO2		GO:0031932	TORC2 complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR		1
TEX10		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	BOP1;DDX27;PELP1;PES1;WDR12		1
TEX10		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	AATF;IMP3;NOP56;UTP4	GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1
TEX264		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|ERphagy	RETREG1;RETREG2;RETREG3;RTN3;SEC62	GO:0061709 reticulophagy	1
TFB1M		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0000154 rRNA modification	1
TFB1M		GO:0061668	mitochondrial ribosome assembly	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0180026 mitochondrial small ribosomal subunit assembly	1
TFE3		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TFE3 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TFE3 transcriptional program|Transcription factor	TFE3	GO:0003700 DNA-binding transcription factor activity	1
TFEB		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TFEB transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TFEB transcriptional program|Transcription factor	TFEB	GO:0003700 DNA-binding transcription factor activity	1
TIMM10		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TIMM10B		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TIMM13		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TIMM17A		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM17A		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TIMM17B		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM17B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TIMM21		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM21		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0030150 protein import into mitochondrial matrix	1
TIMM22		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0071806 protein transmembrane transport	1
TIMM22		GO:0042721	TIM22 mitochondrial import inner membrane insertion complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	AGK;TIMM22;TIMM29	GO:0042721 TIM22 mitochondrial import inner membrane insertion complex	1
TIMM23		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM23		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TIMM23B		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM23B		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TIMM29		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
TIMM29		GO:0042721	TIM22 mitochondrial import inner membrane insertion complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex	AGK;TIMM22;TIMM29	GO:0042721 TIM22 mitochondrial import inner membrane insertion complex	1
TIMM44		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM44		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0030150 protein import into mitochondrial matrix	1
TIMM50		GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TIMM17A;TIMM17B;TIMM21;TIMM23;TIMM23B	GO:0005744 TIM23 mitochondrial import inner membrane translocase complex	1
TIMM50		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM17/23 complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0030150 protein import into mitochondrial matrix	1
TIMM8A		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TIMM8B		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TIMM9		GO:0042719	mitochondrial intermembrane space chaperone complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	Mitochondrial proteostasis|Chaperone|Small intermembrane space chaperone	TIMM10;TIMM10B;TIMM8A;TIMM8B;TIMM9	GO:0042719 mitochondrial intermembrane space chaperone complex	1
TMA16		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
TMA16		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4	GO:0042273 ribosomal large subunit biogenesis	1
TMCO1		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|GEL complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
TMCO1		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|GEL complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
TMED1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED10		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0071806 protein transmembrane transport;GO:0106273 cytosol to ERGIC protein transport	1
TMED2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED5		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED6		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED7		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMED9		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|ER-Golgi trafficking|Antero- and retrograde transport|Cargo receptor	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006886 intracellular protein transport	1
TMEM106B		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Miscellaneous function - lysosomal acidification	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
TMEM129		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated idiosyncratic E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
TMEM129		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated idiosyncratic E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated idiosyncratic E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|C4C4	PRPF19;STUB1;TMEM129;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	2
TMEM147		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
TMEM147		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|BOS complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
TMEM175		GO:0007042	lysosomal lumen acidification	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification	Autophagy-Lysosome Pathway|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|Miscellaneous function - lysosomal acidification	ATP6V0A1;ATP6V0A2;ATP6V0A4;ATP6V0B;TCIRG1		1
TMEM183A		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|transmembrane	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
TMEM183BP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate receptor|F-box|transmembrane	FBXL2;FBXL3;FBXL4;FBXL5;SKP2		1
TMEM259		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|membralin complex|noncatalytic / transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
TMEM67		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated UPS component	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
TMTC1		GO:0006493	protein O-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0035269 protein O-linked glycosylation via mannose	2
TMTC2		GO:0006493	protein O-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0035269 protein O-linked glycosylation via mannose	2
TMTC3		GO:0006493	protein O-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0035269 protein O-linked glycosylation via mannose	2
TMTC4		GO:0006493	protein O-linked glycosylation	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|O-glycosylation system;ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	ER proteostasis|Glycoproteostasis|O-glycosylation system|O-mannosylation	POMT1;POMT2;TMTC1;TMTC2;TMTC3	GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0035269 protein O-linked glycosylation via mannose	2
TMUB1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|membralin complex|noncatalytic / transmembrane, UBL	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
TMUB1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|ER handling of ERAD substrates	DERL1;DERL2;DERL3;ERLIN1;ERLIN2;HERPUD1;JKAMP;SVIP;SYVN1;TMUB1	GO:0036503 ERAD pathway	2
TMUB2		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|membralin complex|noncatalytic / transmembrane, UBL	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
TMX1		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
TMX2		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
TMX3		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10	GO:0003756 protein disulfide isomerase activity	1
TMX4		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
TNFAIP1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul3 substrate receptor|BTB / KCTD type I|other	ENC1;GAN;IPP;KBTBD2;KBTBD3	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
TNFAIP3		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|OTU & A20	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0003824 catalytic activity;GO:0004842 ubiquitin-protein transferase activity	1
TNPO1		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
TNPO1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
TNPO2		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
TNPO2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
TNPO3		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006606 protein import into nucleus;GO:0061608 nuclear import signal receptor activity	2
TNPO3		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus	1
TOLLIP		GO:0035973	aggrephagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Aggrephagy	MAP1S;NBR1;OPTN;SQSTM1;TOLLIP		1
TOM1		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Movement of autophagosomes along actin	ARL8A;ARL8B;CALCOCO2;MAP1LC3B;MYO6;RILP;RUFY3;TAX1BP1;TOM1		2
TOMM20		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM20		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM20		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM20L		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM20L		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM20L		GO:0045040	protein insertion into mitochondrial outer membrane	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
TOMM22		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM22		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0006886 intracellular protein transport;GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM22		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM34		GO:0031072	heat shock protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0031072 heat shock protein binding	1
TOMM40		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM40		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM40		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM40L		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM40L		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM40L		GO:0045040	protein insertion into mitochondrial outer membrane	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008150 biological_process	1
TOMM5		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM5		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
TOMM5		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM6		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM6		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7		1
TOMM6		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM7		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM7		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM7		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TOMM70		GO:0005742	mitochondrial outer membrane translocase complex	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0005742 mitochondrial outer membrane translocase complex	1
TOMM70		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0008320 transmembrane protein transporter activity;GO:0030150 protein import into mitochondrial matrix	1
TOMM70		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
TOMM70		GO:0045040	protein insertion into mitochondrial outer membrane	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport|Outer membrane import	Mitochondrial proteostasis|Protein transport|Outer membrane import|TOMM complex	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7	GO:0045040 protein insertion into mitochondrial outer membrane	1
TONSL		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
TOPBP1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-B complex|BRCT	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
TOPORS		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|SUMO binding domain;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / SUMO binding domain|SIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
TOR1AIP2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|transmembrane	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
TP53		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TP53 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TP53 transcriptional program|Transcription factor	TP53	GO:0003700 DNA-binding transcription factor activity	1
TP53		GO:1904716	positive regulation of chaperone-mediated autophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer	Autophagy-Lysosome Pathway|Chaperone-mediated autophagy|Lysosomal modulator of chaperone-mediated autophagy|Chaperone-mediated autophagy enhancer|Modulator of HSPA8 role in assembly of LAMP2A	AMBRA1;GFAP;MT-RNR2;PSME1;TP53		1
TP53BP1		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA repair accessory|idiosyncratic Ub binding / other	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006303 double-strand break repair via nonhomologous end joining;GO:0097680 double-strand break repair via classical nonhomologous end joining	1
TP63		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TP63 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TP63 transcriptional program|Transcription factor	TP63	GO:0003700 DNA-binding transcription factor activity	1
TP73		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|TP73 transcriptional program|Transcription factor	Autophagy-Lysosome Pathway|Autophagy gene expression|TP73 transcriptional program|Transcription factor	TP73	GO:0003700 DNA-binding transcription factor activity	1
TPP1		GO:0008233	peptidase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal peptidase	DPP4;DPP7;GGH;LGMN;TPP1	GO:0008233 peptidase activity	1
TPR		GO:0005643	nuclear pore	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear pore complex	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0005643 nuclear pore	1
TPR		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear pore complex	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006606 protein import into nucleus;GO:0006886 intracellular protein transport	1
TRAF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|MATH/TRAF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAF3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|MATH/TRAF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAF3IP2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|other	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
TRAF4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|MATH/TRAF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAF5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|MATH/TRAF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAF6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|MATH/TRAF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAF7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAIP		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRAM1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel accessory protein	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation	1
TRAM1L1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel accessory protein	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation	1
TRAM2		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|SEC61 channel accessory protein	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62	GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation	1
TRAP1		GO:0140662	ATP-dependent protein folding chaperone	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Mitochondrial proteostasis|Chaperone|HSP90 system|HSP90	Mitochondrial proteostasis|Chaperone|HSP90 system|HSP90	TRAP1	GO:0140662 ATP-dependent protein folding chaperone	1
TRAPPC1		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC11		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC12		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC13		GO:0030008	TRAPP complex	entailed_by_goa_closure	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:1990072 TRAPPIII protein complex	1
TRAPPC3		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC4		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC5		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRAPPC8		GO:0030008	TRAPP complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Autophagy component recruitment to autophagophore|TRAPP complex component	TRAPPC1;TRAPPC3;TRAPPC4;TRAPPC5;TRAPPC8	GO:0030008 TRAPP complex	1
TRIB3		GO:0006954	inflammatory response	new_to_goa	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor regulator|Inflammatory response	PN regulation|Transcription factor regulator|Inflammatory response|NFkB modulator	TRIB3		1
TRIM10		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM11		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM13		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
TRIM13		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class XI|transmembrane	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
TRIM13		GO:0061709	reticulophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|Ubiquitination of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|Ubiquitination of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1		2
TRIM14		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM15		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM16		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM16		GO:0160247	autophagy cargo adaptor activity	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Lysophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Lysophagy	CALCOCO2;TRIM16		1
TRIM16L		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & SPRY & folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9		1
TRIM17		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM17		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Midbody autophagy	NBR1;SQSTM1;TRIM17	GO:0006914 autophagy;GO:0030674 protein-macromolecule adaptor activity	1
TRIM2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VII|FIL, TolB-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM21		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM22		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM23		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IX|ARF, P-loop NTP hydrolase	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM24		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VI|PHD-type ZnF, Bromodomain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM25		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
TRIM25		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated RING E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;RNF103;RNF139;RNF145;RNF170;RNFT1;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
TRIM26		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM27		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM28		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VI|PHD-type ZnF, Bromodomain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM29		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & assorted CTD	MID1;MID2;TRIM36;TRIM46;TRIM9		1
TRIM3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VII|FIL, TolB-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM31		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|various CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM32		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VII|TolB-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM33		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VI|PHD-type ZnF, Bromodomain	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM34		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM35		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM36		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM37		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VIII|MATH	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM38		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM39		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM40		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|no CTD & folded helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM41		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM42		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class III|COS, FN	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM43		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM43B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM44		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & no CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM45		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class X|FIL	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM46		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9		1
TRIM47		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM48		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|no CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM49		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM49B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM49C		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM49D1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM49D2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / TRIM class IV|SIM	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
TRIM5		GO:0098792	xenophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Xenophagy	CALCOCO2;OPTN;SQSTM1;TAX1BP1;TRIM5	GO:0006914 autophagy	1
TRIM50		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM51		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM51G		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM52		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|no CTD & short central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM54		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class II|COS	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM55		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class II|COS	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM56		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|TolB-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM58		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM59		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class XI|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM6		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM60		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM61		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|no CTD & short central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM62		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM63		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class II|COS	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM64		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM64B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM64C		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV homolog|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM65		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM66		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & assorted CTD	MID1;MID2;TRIM36;TRIM46;TRIM9		1
TRIM67		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9		1
TRIM68		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY - folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM69		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM71		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class VII|FIL, TolB-like	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM72		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM73		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|no CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM74		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|no CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM75		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM77		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM8		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class V|various CTD	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIM9		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class I|COS, FN, SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIML1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / class IV|SPRY	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIML2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRIM / unclassified|ringless & SPRY & folded central helix	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
TRIP12		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|Armadillo-like, WWE;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|HECT|Armadillo-like	ITCH;NEDD4;NEDD4L;PRKN;SMURF1;SMURF2;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	2
TRIP4		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
TRIP4		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
TRMT10C		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|pre-rRNA processing nuclease|Subunit of RNAse P complex	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
TRMT112		GO:0030688	preribosome, small subunit precursor	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1	GO:0032991 protein-containing complex	1
TRMT112		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0000470 maturation of LSU-rRNA;GO:0030490 maturation of SSU-rRNA;GO:0031167 rRNA methylation;GO:0070476 rRNA (guanine-N7)-methylation	1
TRMT2B		GO:0000154	rRNA modification	more_specific_than_existing_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B	GO:0006396 RNA processing	1
TRMT2B		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
TRMT61B		GO:0000154	rRNA modification	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	MRM1;MRM2;MRM3;RPUSD4;TRMT61B		1
TRMT61B		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|39S subunit rRNA modification|rRNA methylation	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B		1
TRPC4AP		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|non-WD40|other	BRWD1;BRWD3;DCAF1;DCAF6;PHIP	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
TSC1		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
TSFM		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	GFM1;GUF1;TSFM;TUFM	GO:0003746 translation elongation factor activity	1
TSG101		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
TSG101		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
TSPO		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Inhibits mitochondrial protein ubiquitination	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901525 negative regulation of mitophagy	1
TSR1		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
TSR1		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
TSR2		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
TSR2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1
TSR3		GO:0000154	rRNA modification	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0000154 rRNA modification	1
TSR3		GO:0030688	preribosome, small subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex	BUD23;BYSL;EIF5B;LTV1;NOB1		1
TSR3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-40S complex;Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0000154 rRNA modification;GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA	2
TTC1		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
TTC12		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and Armadillo domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
TTC13		GO:0051879	Hsp90 protein binding	no_local_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|TPR domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6		1
TTC3		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
TTC3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml;ubiquitin_proteasome_system.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ubiquitin binding domain|TTC3/DZIP3, TPR;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / with UBD|UBA-like (other)	ASB2;FBXW4;FBXW7;FBXW8;LONRF3;MID1;MID2;PML;STUB1;TRIM36;TRIM46;TRIM9;TTC3;WDTC1	GO:0061630 ubiquitin protein ligase activity	3
TTC31		GO:0051879	Hsp90 protein binding	no_local_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|TPR domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6		1
TTC4		GO:0031072	heat shock protein binding	entailed_by_goa_closure	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR and Cns1/TTC4 wheel domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0030544 Hsp70 protein binding;GO:0051879 Hsp90 protein binding	1
TTC9		GO:0031072	heat shock protein binding	no_local_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4		1
TTC9B		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0003674 molecular_function	1
TTC9C		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain containing	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
TTI1		GO:0031931	TORC1 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, direct|mTORC1 complex component	AKT1S1;DEPTOR;MLST8;MTOR;RPTOR	GO:0031931 TORC1 complex	1
TTI1		GO:0031932	TORC2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Insulin signaling pathway|AKT1 activator, mTORC2 complex component	DEPTOR;MAPKAP1;MLST8;MTOR;RICTOR	GO:0031932 TORC2 complex	1
TUFM		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Selective autophagy receptor|Mitophagy	CALCOCO2;FUNDC1;OPTN;SQSTM1;TAX1BP1		1
TUFM		GO:0003746	translation elongation factor activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	Translation|Mitochondrial translation|Translation elongation|assorted elongation factors	GFM1;GUF1;TSFM;TUFM	GO:0003746 translation elongation factor activity	1
TUSC3		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
TUSC3		GO:0008250	oligosaccharyltransferase complex	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	ER proteostasis|Glycoproteostasis|N-glycosylation system|Oligosaccharyl transferase complex component	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0008250 oligosaccharyltransferase complex	1
TXNDC11		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
TXNDC12		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
TXNDC16		GO:0003756	protein disulfide isomerase activity	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Folding enzyme|Protein disulfide isomerases	ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10		1
TXNDC5		GO:0003756	protein disulfide isomerase activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;er_proteostasis.yaml	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protein disulfide isomerase;ER proteostasis|Folding enzyme|Protein disulfide isomerases	Autophagy-Lysosome Pathway|Lysosomal catabolism|Lysosomal protein catabolism|Lysosomal protein disulfide isomerase;ER proteostasis|Folding enzyme|Protein disulfide isomerases	AGR2;AGR3;CASQ1;CASQ2;DNAJC10;TXNDC5	GO:0003756 protein disulfide isomerase activity	2
UBA1		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of ubiquitin	Ubiquitin Proteasome System|E1 activating enzymes|activation of ubiquitin	UBA1	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBA2		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of SUMO	Ubiquitin Proteasome System|E1 activating enzymes|activation of SUMO	SAE1;UBA2	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBA3		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of NEDD8	Ubiquitin Proteasome System|E1 activating enzymes|activation of NEDD8	NAE1;UBA3	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBA5		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UBA5		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of UFM1	Ubiquitin Proteasome System|E1 activating enzymes|activation of UFM1	UBA5	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBA5		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1;UFM1	GO:0061709 reticulophagy	2
UBA5		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
UBA52		GO:0022625	cytosolic large ribosomal subunit	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPL3;RPL3L;RPL4;RPL5;RPL6	GO:0022625 cytosolic large ribosomal subunit	1
UBA52		GO:0022626	cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome;Translation|Cytosolic translation|Ribosome|Cytoribosome	Translation|Cytosolic translation|Ribosome|Cytoribosome|60S subunit	RPS2;RPS3;RPS3A;RPS4X;RPS4Y1	GO:0022626 cytosolic ribosome	2
UBA6		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of ubiquitin and FAT10	Ubiquitin Proteasome System|E1 activating enzymes|activation of ubiquitin and FAT10	UBA6	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBA7		GO:0008641	ubiquitin-like modifier activating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E1 activating enzymes|activation of ISG15	Ubiquitin Proteasome System|E1 activating enzymes|activation of ISG15	UBA7	GO:0008641 ubiquitin-like modifier activating enzyme activity	1
UBAC1		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|KPC complex|noncatalytic / UBL, UBA, STI	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
UBAC1		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBAC1		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL|UBA, STI	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B	GO:0070628 proteasome binding	2
UBAC2		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|LMBR1L-GP78-UBAC2 complex|noncatalytic / UBA, transmembrane	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
UBAP1		GO:0000045	autophagosome assembly	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C		1
UBAP1		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
UBAP2		GO:0006281	DNA repair	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|RNA polymerase II removal|UBA (UBAP2)	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH		1
UBAP2L		GO:0006281	DNA repair	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|RNA polymerase II removal|UBA (UBAP2)	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH		1
UBE2A		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 2|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 2|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2B		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 2|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 2|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2C		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 12|UBC domain & N-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 12|UBC domain & N-terminal extension	UBE2A;UBE2B;UBE2C;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2D1		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
UBE2D1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2D2;UBE2D3;UBE2D4;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	3
UBE2D2		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Ubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
UBE2D2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2D2;UBE2D3;UBE2D4;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2D3		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Ubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
UBE2D3		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2D2;UBE2D3;UBE2D4;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2D4		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2D2;UBE2D3;UBE2D4;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2E1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & N-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & N-terminal extension	UBE2A;UBE2B;UBE2E1;UBE2E3;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2E2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination, ISG15ylation	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination, ISG15ylation|Family 4|UBC domain & N-terminal extension	UBE2E2;UBE2L6	GO:0061631 ubiquitin conjugating enzyme activity	1
UBE2E3		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & N-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & N-terminal extension	UBE2A;UBE2B;UBE2E1;UBE2E3;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2F		GO:0019788	NEDD8 transferase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|NEDDylation	Ubiquitin Proteasome System|E2 conjugating enzymes|NEDDylation|Family 8	UBE2F;UBE2M	GO:0019788 NEDD8 transferase activity	1
UBE2G1		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
UBE2G1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain only	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	3
UBE2G2		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
UBE2G2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain only	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain only	UBE2A;UBE2B;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	3
UBE2G2		GO:0061724	lipophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lipophagy|Ubiquitination of lipid droplet surface proteins	ADRB2;AUP1;RAB7A;RAB7B;UBE2G2		1
UBE2H		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 6|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 6|UBC domain & C-terminal extension	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2H;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2I		GO:0019789	SUMO transferase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|SUMOylation;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E2 conjugating enzyme for SUMO	Ubiquitin Proteasome System|E2 conjugating enzymes|SUMOylation|Family 7;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E2 conjugating enzyme for SUMO|Family 7|backside SUMO binding	UBE2I	GO:0019789 SUMO transferase activity	2
UBE2J1		GO:0036503	ERAD pathway	already_in_goa_exact	exact	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Retrotranslocation channel complex	DERL1;DERL2;DERL3;HERPUD1;SYVN1	GO:0036503 ERAD pathway	1
UBE2J1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 5|UBC domain & transmembrane domain	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 5|UBC domain & transmembrane domain	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2J1;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2J2		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
UBE2J2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 5|UBC domain & transmembrane domain	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 5|UBC domain & transmembrane domain	UBE2A;UBE2B;UBE2D1;UBE2G1;UBE2G2;UBE2J1;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	3
UBE2K		GO:0036503	ERAD pathway	new_to_goa	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K		2
UBE2K		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated E2 conjugating enzyme;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 1|UBC domain & UBA domain	UBE2A;UBE2B;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2L3		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Ubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
UBE2L3		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 15|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 15|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2L3;UBE2L5	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2L5		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 15|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 15|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2L3;UBE2L5	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2L6		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination, ISG15ylation	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination, ISG15ylation|Family 15|UBC domain only	UBE2E2;UBE2L6	GO:0061631 ubiquitin conjugating enzyme activity	1
UBE2M		GO:0019788	NEDD8 transferase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|NEDDylation	Ubiquitin Proteasome System|E2 conjugating enzymes|NEDDylation|Family 8	UBE2F;UBE2M	GO:0019788 NEDD8 transferase activity	1
UBE2N		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Ubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
UBE2N		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 9|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 9|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2N	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2O		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|E3 with intrinsic E2;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|E3 with intrinsic E2|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|E3 with intrinsic E2|idiosyncratic Ub binding / other	ASB2;BIRC6;FBXW4;FBXW7;FBXW8;PML;UBE2O	GO:0061630 ubiquitin protein ligase activity	2
UBE2O		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 14|E2-E3 chimera	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 14|E2-E3 chimera	BIRC6;UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2O	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2Q1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 17|UBC domain & RWD-like domain	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	1
UBE2Q2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 17|UBC domain & RWD-like domain	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K	GO:0061631 ubiquitin conjugating enzyme activity	1
UBE2QL1		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 17 homolog|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 17 homolog|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2QL1	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2R2		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 3|UBC domain & C-terminal extension	CDC34;UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2R2	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2S		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 11|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 11|UBC domain & C-terminal extension	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2S	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2T		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 9|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 9|UBC domain & C-terminal extension	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2T	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2U		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & C-terminal extension	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 4|UBC domain & C-terminal extension	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2U	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2W		GO:0061631	ubiquitin conjugating enzyme activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination;Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 13|UBC domain only	Ubiquitin Proteasome System|E2 conjugating enzymes|ubiquitination|Family 13|UBC domain only	UBE2A;UBE2B;UBE2G1;UBE2G2;UBE2K;UBE2W	GO:0061631 ubiquitin conjugating enzyme activity	2
UBE2Z		GO:0019787	ubiquitin-like protein transferase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|FAT10ylation	Ubiquitin Proteasome System|E2 conjugating enzymes|FAT10ylation|Family 14|UBC domain & N-terminal and C-terminal extensions	UBE2Z	GO:0061631 ubiquitin conjugating enzyme activity	1
UBE3A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|other;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|HECT	ITCH;NEDD4;NEDD4L;PRKN;SMURF1;SMURF2;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	2
UBE3B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|IQ motif	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
UBE3C		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|IQ motif;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|HECT;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|HECT / with IQ|idiosyncratic Ub binding / other	ASB2;FBXW4;FBXW7;FBXW8;ITCH;NEDD4;NEDD4L;PML;PRKN;SMURF1;SMURF2;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	3
UBE3D		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|proposed HECT variant	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
UBE4A		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|other	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
UBE4B		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated UBOX E3 ligase	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
UBE4B		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated UBOX E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated UBOX E3 ligase;Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING variant / UBOX|idiosyncratic Ub binding / other;Ubiquitin Proteasome System|VCP and associated proteins|associated E3 ligases|UBOX|VBM	AMFR;ASB2;FBXW4;FBXW7;FBXW8;PML;PRPF19;RNF125;RNF31;STUB1;SYVN1;UBE4A;UBE4B;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	4
UBL4A		GO:0006620	post-translational protein targeting to endoplasmic reticulum membrane	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|GET pathway component	ER proteostasis|Protein transport|GET pathway component	CAMLG;GET1;GET3;GET4;SGTA	GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane	1
UBL4A		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|GET pathway component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
UBL7		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBN1		GO:0140713	histone chaperone activity	new_to_goa	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1		1
UBOX5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|RING (non-overlapping)	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
UBQLN1		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Degradation of mitochondrial membrane proteins that fail targeting	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
UBQLN1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
UBQLN1		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBQLN1		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
UBQLN2		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Degradation of mitochondrial membrane proteins that fail targeting	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
UBQLN2		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
UBQLN2		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBQLN2		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
UBQLN3		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Degradation of mitochondrial membrane proteins that fail targeting	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
UBQLN3		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBQLN3		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
UBQLN4		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Degradation of mitochondrial membrane proteins that fail targeting	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
UBQLN4		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBA, STI	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBQLN4		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|with UBA, STI;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with UBL, STI1|UBA	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
UBQLNL		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Degradation of mitochondrial membrane proteins that fail targeting	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
UBQLNL		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|UBL|UBL only	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		1
UBR1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|UBR|UBR CTD, UBR-type ZnF;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|UBR|UBR-type ZnF	MID1;MID2;PRKN;TRIM36;TRIM46;TRIM9;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	2
UBR2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|UBR|UBR CTD, UBR-type ZnF;Ubiquitin Proteasome System|Proteasome and associated proteins|associated E3 ligase|UBR|UBR-type ZnF	MID1;MID2;PRKN;TRIM36;TRIM46;TRIM9;TRIP12;UBE3A;UBE3C;UBR1	GO:0061630 ubiquitin protein ligase activity	2
UBR3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|UBR|UBR CTD, UBR-type ZnF, TM	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
UBR4		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3 ligase complex|UBR4/KCMF1 complex|catalytic subunit	CALM1;KCMF1;UBR4		1
UBR5		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|UBR-type ZnF;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|HECT / RCC1|UBR-type ZnF, CUE (UBR5)	ASB2;FBXW4;FBXW7;FBXW8;ITCH;NEDD4;NEDD4L;PML;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	2
UBR7		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|PHD variant|UBR-type ZnF	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0061630 ubiquitin protein ligase activity	1
UBTD1		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBD	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBTD2		GO:0043130	ubiquitin binding	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding	Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|ubiquitin binding|UBD	RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3	GO:0005515 protein binding	1
UBXN4		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
UBXN6		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	PLAA;UBXN6;YOD1	GO:0016236 macroautophagy	2
UBXN8		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
UCHL1		GO:0016579	protein deubiquitination	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Deubiquitination of ATG8 homologs	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Deubiquitination of ATG8 homologs	UCHL1;USP10	GO:0016579 protein deubiquitination	1
UCHL1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	BAP1;UCHL1;UCHL3;UCHL5	GO:0004843 cysteine-type deubiquitinase activity	1
UCHL3		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH	BAP1;UCHL1;UCHL3;UCHL5	GO:0101005 deubiquitinase activity	1
UCHL5		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UCH;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB|UCH	BAP1;UCHL1;UCHL3;UCHL5;USP14;USP15	GO:0004843 cysteine-type deubiquitinase activity	2
UFC1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFC1		GO:0019787	ubiquitin-like protein transferase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E2 conjugating enzymes|UFMylation	Ubiquitin Proteasome System|E2 conjugating enzymes|UFMylation|no family designation	UFC1	GO:0061657 UFM1 conjugating enzyme activity;GO:0071568 UFM1 transferase activity	1
UFC1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1;UFM1	GO:0061709 reticulophagy	2
UFC1		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
UFD1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|VCP system for RQC	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFD1		GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|VCP and associated proteins|adaptors|SHP|UT3	Ubiquitin Proteasome System|VCP and associated proteins|adaptors|SHP|UT3	UFD1	GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex	1
UFD1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP accessories	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
UFD1		GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein quality control|ERAD cofactor	Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein quality control|ERAD cofactor|idiosyncratic Ub binding / UT3	AUP1;UFD1	GO:0036503 ERAD pathway	1
UFL1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFL1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1;UFM1	GO:0061709 reticulophagy	2
UFL1		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
UFM1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFM1		GO:0061709	reticulophagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|ERphagy|UFMylation of ER proteins	DDRGK1;TRIM13;UBA5;UFC1;UFL1;UFM1	GO:0061709 reticulophagy	2
UFM1		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
UFSP1		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFSP1		GO:0071567	deUFMylase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP;Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP|deUFMylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP|deUFMylase	UFSP1;UFSP2	GO:0071567 deUFMylase activity	2
UFSP1		GO:0071569	protein ufmylation	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1	GO:0071569 protein ufmylation	1
UFSP2		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
UFSP2		GO:0071567	deUFMylase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP;Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP|deUFMylase	Ubiquitin Proteasome System|DUBs and UBL demodifiers|UFSP|deUFMylase	UFSP1;UFSP2	GO:0071567 deUFMylase activity	2
UFSP2		GO:0071569	protein ufmylation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	Translation|Cytosolic translation|Ribosome-associated QC|UFMylation	DDRGK1;UBA5;UFC1;UFL1;UFM1		1
UGGT1		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Re-glucosylation	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
UGGT2		GO:0006487	protein N-linked glycosylation	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Glycoproteostasis|N-glycosylation system	ER proteostasis|Glycoproteostasis|N-glycosylation system|N-glycan processing|Re-glucosylation	DAD1;DDOST;MAGT1;OSTC;RPN1	GO:0006487 protein N-linked glycosylation	1
UHRF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / UHRF	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|UHRF;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / UHRF	MID1;MID2;TRIM36;TRIM46;TRIM9;UHRF1;UHRF2	GO:0061630 ubiquitin protein ligase activity	2
UHRF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / UHRF	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|UHRF;Ubiquitin Proteasome System|Ubiquitin and UBL proteins|UBL domain|E3 ligases|RING / UHRF	MID1;MID2;TRIM36;TRIM46;TRIM9;UHRF1;UHRF2	GO:0061630 ubiquitin protein ligase activity	2
UIMC1		GO:0000151	ubiquitin ligase complex	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	GID8;MAEA;RANBP10;RMND5A;RMND5B		1
UIMC1		GO:0070531	BRCA1-A complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|BRCA1-A complex|ubiquitin binding	ABRAXAS1;BABAM2;BRCA1;BRCC3;UIMC1	GO:0070531 BRCA1-A complex	1
ULK1		GO:1990316	Atg1/ULK1 kinase complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:1990316 Atg1/ULK1 kinase complex	1
ULK2		GO:1990316	Atg1/ULK1 kinase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:0005737 cytoplasm	1
ULK3		GO:1990316	Atg1/ULK1 kinase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ULK1 pathway, direct|ULK1 complex component	ATG13;RB1CC1;ULK1;ULK2;ULK3	GO:0005737 cytoplasm	1
UMAD1		GO:0000045	autophagosome assembly	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C		1
UMAD1		GO:0000813	ESCRT I complex	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C		1
UNC45A		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and Armadillo domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
UNC45B		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CC-TPR and Armadillo domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
UNK		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Unkempt|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9		1
UNKL		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Unkempt|C3H1-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9		1
UPF1		GO:0006415	translational termination	supported_by_goa_regulation	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Modulation of termination	ABCE1;EIF2D;ETF1;GSPT1;GSPT2	GO:0006449 regulation of translational termination	1
UPF2		GO:0006415	translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Modulation of termination	ABCE1;EIF2D;ETF1;GSPT1;GSPT2		1
UPF3A		GO:0006415	translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Modulation of termination	ABCE1;EIF2D;ETF1;GSPT1;GSPT2		1
UPF3B		GO:0006415	translational termination	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation termination	Translation|Cytosolic translation|Translation termination|Modulation of termination	ABCE1;EIF2D;ETF1;GSPT1;GSPT2		1
USP1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP10		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
USP10		GO:0016579	protein deubiquitination	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Deubiquitination of ATG8 homologs	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|ATG8 homolog processing, direct|Deubiquitination of ATG8 homologs	UCHL1;USP10	GO:0016579 protein deubiquitination	1
USP10		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml;ubiquitin_proteasome_system.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Ataxin-2, C term|other	OTUD3;USP10;USP11;USP15;USP21;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	2
USP11		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP|internal and external UBLs	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP12		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP13		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|UBA	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
USP14		GO:0036503	ERAD pathway	supported_by_goa_regulation	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:1904293 negative regulation of ERAD pathway	2
USP14		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|external UBL;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB|USP	OTUB1;UCHL5;USP11;USP14;USP15;USP19;USP32;USP4;USP48;YOD1	GO:0101005 deubiquitinase activity	3
USP15		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Deubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
USP15		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP|internal and external UBLs;Ubiquitin Proteasome System|Proteasome and associated proteins|associated DUB|USP	UCHL5;USP11;USP14;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	2
USP16		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity	1
USP17L1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L10		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L11		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L12		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L13		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L15		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L17		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L18		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L19		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L2		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L20		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L21		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L22		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L23		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L24		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L25		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L26		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L27		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L28		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L29		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L3		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L30		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L5		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP17L6P		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Usp17 group	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP18		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP19		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
USP19		GO:0051879	Hsp90 protein binding	already_in_goa_exact	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|CS domain containing	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0051879 Hsp90 protein binding	1
USP19		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	er_proteostasis.yaml;ubiquitin_proteasome_system.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|transmembrane|internal UBL	OTUB1;USP11;USP14;USP15;USP19;USP32;USP4;USP48;YOD1	GO:0004843 cysteine-type deubiquitinase activity	2
USP2		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP20		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP, UBP-ZnF	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP21		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
USP21		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml;ubiquitin_proteasome_system.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Translation|Cytosolic translation|Ribosome-associated QC|Deubiquitination;Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	OTUD3;USP10;USP11;USP15;USP21;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	2
USP22		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity	1
USP24		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Armadillo-like|external UBL, UBA	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP25		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|UBA, UIM	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP26		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|PH-like|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP27X		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
USP28		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|UBA	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP29		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|PH-like|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP3		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity	1
USP30		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Deubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901525 negative regulation of mitophagy	1
USP30		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|mitoTAD pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
USP30		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|transmembrane|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP31		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|internal UBL	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP32		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP|internal and external UBLs	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP33		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP, UBP-ZnF	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP34		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Armadillo-like|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP35		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|Deubiquitination of mitochondrial proteins	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
USP35		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Armadillo-like|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP36		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
USP37		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|PH-like|UIM	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP38		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP4		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP|internal and external UBLs	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP40		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP42		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP43		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|internal UBL	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP44		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP45		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP46		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP47		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP48		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|DUSP|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP49		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity	1
USP5		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|UBA	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP50		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP51		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|UBP-ZnF|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity	1
USP54		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|other|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity	1
USP6		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Rab-GTPase-TBC|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
USP7		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|MATH-TRAF|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP8		GO:0000423	mitophagy	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN		1
USP8		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|dimerization, rhodanese-like|other	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity	1
USP9X		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Armadillo-like|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0101005 deubiquitinase activity	1
USP9Y		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP	Ubiquitin Proteasome System|DUBs and UBL demodifiers|USP|Armadillo-like|external UBL	USP11;USP15;USP32;USP4;USP48	GO:0004843 cysteine-type deubiquitinase activity	1
UTP14A		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
UTP14A		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|EMG1 complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA	1
UTP15		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
UTP15		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
UTP18		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
UTP18		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
UTP4		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
UTP4		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
UTP6		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
UTP6		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
UVRAG		GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Class 3 PI3K complex 2, direct|Class 3 PI3K complex 2 component	BECN1;PIK3C3;PIK3R4;SH3GLB1;UVRAG	GO:0032991 protein-containing complex	1
VAMP2		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
VAMP3		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	STX6;VAMP3;VTI1B	GO:0031201 SNARE complex	1
VAMP3		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
VAMP7		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|Formation of SNARE complex to dock MDV to lysosome	SNAP29;STX17;VAMP7	GO:0031201 SNARE complex	1
VAMP7		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
VAMP8		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	RAB8B;SNAP29;STX17;STX7;YKT6	GO:0031201 SNARE complex	1
VAPA		GO:0061906	autophagosome localization	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Recruitment of autophagosome to vicinity of ER	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Localization of the autophagosome|Recruitment of autophagosome to vicinity of ER	ARL8A;ARL8B;MAP1LC3B;OSBPL1A;RILP;RUFY3;VAPA		2
VARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
VARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
VCP		GO:0003743	translation initiation factor activity	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF1;EIF1AX;EIF1AY;EIF4B;EIF4H		1
VCP		GO:0006413	translational initiation	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation initiation	Translation|Cytosolic translation|Translation initiation|assorted initiation factors	EIF2B1;EIF2S1;EIF2S2;EIF2S3;EIF2S3B		1
VCP		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|VCP system for RQC	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0140455 cytoplasm protein quality control	1
VCP		GO:0035694	mitochondrial protein catabolic process	new_to_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|mitoTAD pathway	ANKZF1;FAF2;MARCHF5;USP30;VCP		1
VCP		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|VCP system for retrotranslocation in ERAD|VCP	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBQLN1;UBQLN2;UBXN4;UBXN8;VCP	GO:0036503 ERAD pathway	2
VCP		GO:0043335	protein unfolding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|VCP and associated proteins|VCP	Ubiquitin Proteasome System|VCP and associated proteins|VCP	VCP	GO:0043335 protein unfolding	1
VCP		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lysophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lysophagy|ELDR complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Lysophagy|ELDR complex component	VCP	GO:0006914 autophagy;GO:0016236 macroautophagy	2
VDAC1		GO:0000423	mitophagy	supported_by_goa_regulation	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Marking substrates for selective autophagy|Mitophagy|PINK/PRKN pathway	CLEC16A;PARL;PGAM5;PINK1;PRKN	GO:1901524 regulation of mitophagy;GO:1901526 positive regulation of mitophagy;GO:1905091 positive regulation of type 2 mitophagy	1
VHL		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|VHL	APPBP2;FEM1A;FEM1B;FEM1C;VHL	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
VPS11		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS11		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|VPS-associated|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
VPS13D		GO:0000423	mitophagy	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Mitophagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Mitophagy|Binding of ubiquitin-marked mitochondria	FBXO7;VPS13D	GO:0016236 macroautophagy	1
VPS16		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS18		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS18		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|VPS-associated|non-WD40	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
VPS28		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
VPS28		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
VPS33A		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS37A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component;Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|Localization of the ESCRT-III complex	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	2
VPS37A		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
VPS37B		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
VPS37B		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
VPS37C		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
VPS37C		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
VPS37D		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0016236 macroautophagy	1
VPS37D		GO:0000813	ESCRT I complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-I complex component	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0000813 ESCRT I complex	1
VPS39		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS41		GO:0030897	HOPS complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|HOPS complex component;Autophagy-Lysosome Pathway|Microautophagy|Micromitophagy|PDH-positive MDV-mediated micromitophagy|HOPS complex component	VPS11;VPS16;VPS18;VPS33A;VPS39	GO:0030897 HOPS complex	2
VPS41		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|VPS-associated|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9		1
VPS4A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex activity modulator	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0007033 vacuole organization;GO:0016236 macroautophagy	1
VPS4A		GO:0000815	ESCRT III complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0005737 cytoplasm;GO:0005768 endosome;GO:0010008 endosome membrane	1
VPS4B		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex activity modulator	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0007033 vacuole organization;GO:0016236 macroautophagy	1
VPS4B		GO:0000815	ESCRT III complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0005737 cytoplasm;GO:0005768 endosome;GO:0010008 endosome membrane	1
VPS72		GO:0140713	histone chaperone activity	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Chaperone|Histone chaperone	Nuclear proteostasis|Chaperone|Histone chaperone	ASF1A;ASF1B;CHAF1A;NPM1	GO:0140713 histone chaperone activity	1
VPS8		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|VPS-associated|WD40	MID1;MID2;TRIM36;TRIM46;TRIM9		1
VTI1A		GO:0000045	autophagosome assembly	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Sealing of autophagophore membrane|ESCRT-III complex activity modulator	TSG101;VPS28;VPS37A;VPS37B;VPS37C	GO:0006914 autophagy;GO:0016236 macroautophagy	1
VTI1A		GO:0000815	ESCRT III complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	Autophagy-Lysosome Pathway|Microautophagy|General microautophagy machinery|ESCRT-III complex component	CHMP1A;CHMP1B;CHMP2A;CHMP2B;CHMP3	GO:0005737 cytoplasm;GO:0005768 endosome;GO:0012505 endomembrane system;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle;GO:0098588 bounding membrane of organelle	1
VTI1B		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-endosome docking|Lysosome-endosome SNARE complex	STX6;VAMP3;VTI1B	GO:0031201 SNARE complex	1
VTI1B		GO:1905686	positive regulation of plasma membrane repair	new_to_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input;Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG16L1-positive plasma membrane input|Autophagophore-vesicle SNARE complex	STX7;STX8;VAMP3;VAMP7;VTI1B		2
WARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
WARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
WDFY3		GO:0035973	aggrephagy	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Aggrephagy	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Aggrephagy	WDFY3	GO:0035973 aggrephagy	1
WDR12		GO:0030687	preribosome, large subunit precursor	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	BOP1;DDX27;PELP1;PES1;WDR12	GO:0030687 preribosome, large subunit precursor	1
WDR12		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|PeBoW complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
WDR18		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	BOP1;DDX27;PELP1;PES1;WDR12		1
WDR18		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|Rix1 complex	AATF;IMP3;NOP56;UTP4	GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006364 rRNA processing	1
WDR24		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component	MIOS;SEC13;SEH1L;WDR24;WDR59	GO:0061700 GATOR2 complex	1
WDR26		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / LisH, WD40	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
WDR3		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
WDR3		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
WDR36		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
WDR36		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-B complex	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing;GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
WDR43		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
WDR43		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0030490 maturation of SSU-rRNA;GO:0042274 ribosomal small subunit biogenesis	1
WDR45		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0005737 cytoplasm;GO:0034045 phagophore assembly site membrane	1
WDR45B		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0034045 phagophore assembly site membrane	1
WDR59		GO:0061700	GATOR2 complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml;ubiquitin_proteasome_system.yaml	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component;Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein kinases & regulators|GATOR2 complex	Autophagy-Lysosome Pathway|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|GATOR2 complex component;Ubiquitin Proteasome System|Ubiquitin and UBL binding|protein kinases & regulators|GATOR2 complex|RWD	MIOS;SEC13;SEH1L;WDR24;WDR59	GO:0061700 GATOR2 complex	2
WDR75		GO:0032040	small-subunit processome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	HEATR1;UTP15;UTP4;WDR43;WDR75	GO:0032040 small-subunit processome	1
WDR75		GO:0042254	ribosome biogenesis	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|SSU processosome|UTP-A complex	AATF;IMP3;NOP56;UTP4	GO:0042254 ribosome biogenesis	1
WDR83OS		GO:0015031	protein transport	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	SEC61A1;SEC61A2;SEC61B;SEC61G;SEC62		1
WDR83OS		GO:0044743	protein transmembrane import into intracellular organelle	new_to_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	NCLN;NOMO1;RAB5IF;TMCO1;TMEM147		1
WDR83OS		GO:0160005	PAT complex	more_specific_than_existing_goa	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	ER proteostasis|Protein transport|Transmembrane protein import|PAT complex component	CCDC47;WDR83OS	GO:0005789 endoplasmic reticulum membrane	1
WDSUB1		GO:0061630	ubiquitin protein ligase activity	more_specific_than_existing_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING variant|UBOX|WD40	PRPF19;STUB1;UBE4A;UBOX5;WDSUB1	GO:0004842 ubiquitin-protein transferase activity	1
WDTC1		GO:0031072	heat shock protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	DNAAF4;DNAJC7;SMYD4;TTC12;TTC4	GO:0005515 protein binding	1
WDTC1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	Cytonuclear proteostasis|Chaperone|HSP70-HSP90 system integration|HSP70-HSP90 joint cochaperone|CC-TPR domain and Ub ligase	LONRF3;STUB1;TTC3;WDTC1		1
WDTC1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul4A/Cul4B substrate receptor|WD40|TPR	BRWD1;BRWD3;DCAF1;DCAF6;PHIP		1
WIPI1		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0005737 cytoplasm;GO:0034045 phagophore assembly site membrane	1
WIPI2		GO:0062079	ATG2-ATG18 complex	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|ATG2-WIPI complex component	ATG2A;ATG2B;WDR45B;WIPI1;WIPI2	GO:0000407 phagophore assembly site;GO:0016020 membrane;GO:0032991 protein-containing complex;GO:0034045 phagophore assembly site membrane	1
WRNIP1		GO:0006260	DNA replication	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication|DNA polymerase accessory|UBZ4-type ZnF	RFC1;WRNIP1;ZRANB3	GO:0006260 DNA replication	1
WWP1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
WWP2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|HECT|NEDD4-type / WW & C2|ubiquitination	ITCH;NEDD4;NEDD4L;SMURF1;SMURF2	GO:0061630 ubiquitin protein ligase activity	1
WWTR1		GO:0003713	transcription coactivator activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator;Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator|Cellular mechanics sensing	Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator|Cellular mechanics sensing	WWTR1;YAP1	GO:0003713 transcription coactivator activity	2
XBP1		GO:0003700	DNA-binding transcription factor activity	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	HIF1A;HSF1;HSF2;HSF4;HSF5	GO:0003700 DNA-binding transcription factor activity	1
XBP1		GO:0006986	response to unfolded protein	entailed_by_goa_closure	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	ATF6;XBP1	GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036498 IRE1-mediated unfolded protein response;GO:0036500 ATF6-mediated unfolded protein response	1
XBP1		GO:0030968	endoplasmic reticulum unfolded protein response	already_in_goa_exact	ok_for_propagation_to_go	pn_regulation.yaml	PN regulation|Transcription factor|Unfolded protein response	PN regulation|Transcription factor|Unfolded protein response|Transcription of unfolded protein response genes	ATF6;XBP1	GO:0030968 endoplasmic reticulum unfolded protein response	1
XIAP		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|BIRC / IAP|BIR repeat;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / BIRC, IAP|UBA (BIRC2/3)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
XPA		GO:0006281	DNA repair	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|binding to damaged DNA|UBZ (XPA)	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006281 DNA repair	1
XPNPEP3		GO:0017087	mitochondrial processing peptidase complex	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0005737 cytoplasm;GO:0005739 mitochondrion	1
XPNPEP3		GO:0034982	mitochondrial protein processing	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Mitochondrial protein maturation	Mitochondrial proteostasis|Mitochondrial protein maturation|Processing peptidase	IMMP1L;IMMP2L;METAP1D;MIPEP;XPNPEP3	GO:0006508 proteolysis;GO:0016485 protein processing	1
XPO1		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006913 nucleocytoplasmic transport	2
XPO1		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
XPO4		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0005049 nuclear export signal receptor activity;GO:0006611 protein export from nucleus	2
XPO4		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus	1
XPO5		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0005049 nuclear export signal receptor activity;GO:0006405 RNA export from nucleus;GO:0006611 protein export from nucleus;GO:0035281 pre-miRNA export from nucleus	2
XPO5		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
XPO6		GO:0006913	nucleocytoplasmic transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0005049 nuclear export signal receptor activity;GO:0006611 protein export from nucleus	2
XPO6		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
XPO7		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006913 nucleocytoplasmic transport	2
XPO7		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006611 protein export from nucleus;GO:0006886 intracellular protein transport	1
XPOT		GO:0006913	nucleocytoplasmic transport	already_in_goa_exact	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport|Nuclear transport receptor;Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	HIKESHI;IPO4;IPO5;KPNA2;KPNB1;TNPO1;TNPO2;XPO1	GO:0006913 nucleocytoplasmic transport	2
XPOT		GO:0015031	protein transport	entailed_by_goa_closure	ok_for_propagation_to_go	nuclear_proteostasis.yaml	Nuclear proteostasis|Protein transport	Nuclear proteostasis|Protein transport|Nuclear transport receptor|Importin, beta type	GLE1;NUP214;NUP88;RAE1;RANBP2	GO:0006886 intracellular protein transport	1
XRCC4		GO:0006281	DNA repair	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA repair|DNA repair accessory|SIM	ABRAXAS1;ABRAXAS2;BABAM2;GCNA;POLH	GO:0006284 base-excision repair;GO:0006302 double-strand break repair;GO:0006303 double-strand break repair via nonhomologous end joining	1
XRN2		GO:0006364	rRNA processing	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	EXOSC10;FCF1;NOB1;PARN;RMRP	GO:0006364 rRNA processing	1
XRN2		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex	BOP1;DDX27;PELP1;PES1;WDR12		1
XRN2		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|XND complex;Translation|Cytosolic translation|Ribosome biogenesis factor|pre-rRNA processing nuclease	AATF;IMP3;NOP56;UTP4	GO:0006364 rRNA processing	2
YAP1		GO:0003713	transcription coactivator activity	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator;Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator|Cellular mechanics sensing	Autophagy-Lysosome Pathway|Autophagy gene expression|Transcriptional coactivator|Cellular mechanics sensing	WWTR1;YAP1	GO:0003713 transcription coactivator activity	2
YARS1		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	Translation|Cytosolic translation|Translation elongation|tRNA synthetase	AARS1;CARS1;DARS1;EPRS1;FARSA	GO:0004812 aminoacyl-tRNA ligase activity	1
YARS2		GO:0004812	aminoacyl-tRNA ligase activity	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	Translation|Mitochondrial translation|Translation elongation|tRNA synthetase	AARS2;CARS2;DARS2;EARS2;FARS2	GO:0004812 aminoacyl-tRNA ligase activity	1
YBEY		GO:0061668	mitochondrial ribosome assembly	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Mitochondrial translation|Mitoribosome biogenesis factor;Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit assembly	Translation|Mitochondrial translation|Mitoribosome biogenesis factor|28S subunit assembly	METTL15;MTERF4;NSUN4;TFB1M;TRMT2B;YBEY		2
YKT6		GO:0031201	SNARE complex	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	Autophagy-Lysosome Pathway|Autophagosome closure maturation and lysosome fusion|Autophagosome-lysosome docking|Lysosome-autophagosome SNARE complex	RAB8B;SNAP29;STX17;STX7;YKT6	GO:0031201 SNARE complex	1
YME1L1		GO:0005759	mitochondrial matrix	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	AFG3L2;CLPX;PITRM1;SPG7;YME1L1	GO:0005739 mitochondrion	1
YME1L1		GO:0035694	mitochondrial protein catabolic process	already_in_goa_exact	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Organelle-specific protein degradation	Mitochondrial proteostasis|Organelle-specific protein degradation|Matrix protease	ANKZF1;FAF2;MARCHF5;USP30;VCP	GO:0035694 mitochondrial protein catabolic process	1
YOD1		GO:0036503	ERAD pathway	already_in_goa_exact	exact;ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation;ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	DERL1;DERL2;DERL3;HERPUD1;SYVN1;UBE2D1;UBE2G1;UBE2G2;UBE2J2;UBE2K	GO:0036503 ERAD pathway	2
YOD1		GO:0101005	deubiquitinase activity	already_in_goa_exact	ok_for_propagation_to_go	er_proteostasis.yaml	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	ER proteostasis|Organelle-specific protein degradation|ER associated degradation|Cytosolic handling of ERAD substrates|ERAD-associated DUB	OTUB1;USP14;USP19;YOD1	GO:0101005 deubiquitinase activity	1
YOD1		GO:0160247	autophagy cargo adaptor activity	more_specific_than_existing_goa	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy;Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	Autophagy-Lysosome Pathway|Autophagy substrate selection|Substrate selectivity regulator for selective autophagy|Lysophagy|ELDR complex component	PLAA;UBXN6;YOD1	GO:0016236 macroautophagy	2
YPEL1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|FBXL2/FBXL20 specific	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
YPEL2		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|FBXL2/FBXL20 specific	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
YPEL3		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|FBXL2/FBXL20 specific	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
YPEL4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul1 substrate adaptor|FBXL2/FBXL20 specific	IFI27;MAGEA11;PDLIM2;YPEL1;YPEL2		1
YPEL5		GO:0000151	ubiquitin ligase complex	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic RING complex|CTLH complex|noncatalytic / Yippee	GID8;MAEA;RANBP10;RMND5A;RMND5B	GO:0000151 ubiquitin ligase complex	1
YWHAE		GO:0015031	protein transport	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport;Mitochondrial proteostasis|Protein transport|Cytosolic mitochondria import stimulation factor	Mitochondrial proteostasis|Protein transport|Cytosolic mitochondria import stimulation factor	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7;YWHAE;YWHAZ	GO:0008104 intracellular protein localization	2
YWHAZ		GO:0015031	protein transport	more_specific_than_existing_goa	ok_for_propagation_to_go	mitochondrial_proteostasis.yaml	Mitochondrial proteostasis|Protein transport;Mitochondrial proteostasis|Protein transport|Cytosolic mitochondria import stimulation factor	Mitochondrial proteostasis|Protein transport|Cytosolic mitochondria import stimulation factor	TOMM20;TOMM20L;TOMM5;TOMM6;TOMM7;YWHAE;YWHAZ	GO:0008104 intracellular protein localization	2
ZCCHC4		GO:0000154	rRNA modification	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	BUD23;EMG1;LOC124902573;NAT10;TSR3	GO:0031167 rRNA methylation	1
ZCCHC4		GO:0042254	ribosome biogenesis	entailed_by_goa_closure	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|rRNA modification	AATF;IMP3;NOP56;UTP4	GO:0031167 rRNA methylation	1
ZER1		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor|VHL box|ZER1 group / Armadillo-like	ZER1;ZSWIM4;ZSWIM5;ZSWIM6;ZSWIM8		1
ZFAND1		GO:0070628	proteasome binding	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|AN1|other	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B	GO:0070628 proteasome binding	1
ZFAND2A		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|AN1|UBZ;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with AN1|UBZ (ZFAND2A/B)	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
ZFAND2B		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|VCP and proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|AN1|UIM;Ubiquitin Proteasome System|Ubiquitin and UBL binding|VCP and proteasome adaptor|with AN1|UIM, UBZ (ZFAND2A/B)	AKIRIN1;AKIRIN2;ZFAND1;ZFAND2A;ZFAND2B		2
ZFAND5		GO:0070628	proteasome binding	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor	Ubiquitin Proteasome System|Proteasome and associated proteins|adaptors|AN1|A20;Ubiquitin Proteasome System|Ubiquitin and UBL binding|proteasome adaptor|with AN1|A20 ZnF	AKIRIN1;AKIRIN2;RAD23A;RAD23B;UBQLN1;UBQLN2;UBQLN3;ZFAND1;ZFAND2A;ZFAND2B		2
ZFP42		GO:0006364	rRNA processing	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	REXO2;ZFP42		1
ZFP42		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-5S rRNA processing nuclease	AATF;IMP3;NOP56;UTP4		1
ZFP91		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|idiosyncratic E3|C2H2 ZnF (one cluster)	KAT2B;PPARA;PPARG;TNFAIP3;ZFP91	GO:0061630 ubiquitin protein ligase activity	1
ZFPL1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
ZFTRAF1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|TRAF-type ZnF|other	MID1;MID2;TRIM36;TRIM46;TRIM9		1
ZFYVE1		GO:0032266	phosphatidylinositol-3-phosphate binding	already_in_goa_exact	ok_for_propagation_to_go	autophagy_lysosome_pathway.yaml	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|PI(3)P sequestration	Autophagy-Lysosome Pathway|Autophagophore initiation and elongation|Regulation of autophagophore membrane composition|PI(3)P sequestration	ZFYVE1	GO:0032266 phosphatidylinositol-3-phosphate binding	1
ZMYND10		GO:0051879	Hsp90 protein binding	more_specific_than_existing_goa	ok_for_propagation_to_go	chaperone_systems.yaml	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone	Cytonuclear proteostasis|Chaperone|HSP90 system|HSP90 cochaperone|no characteristic domain	CACYBP;CHORDC1;CYB5R4;DNAAF11;DNAAF6	GO:0005515 protein binding	1
ZNF593		GO:0030687	preribosome, large subunit precursor	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	BOP1;DDX27;PELP1;PES1;WDR12		1
ZNF593		GO:0042254	ribosome biogenesis	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome biogenesis factor	Translation|Cytosolic translation|Ribosome biogenesis factor|pre-60S complex|non 5S RNP complex	AATF;IMP3;NOP56;UTP4		1
ZNF598		GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	new_to_goa	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1		1
ZNF598		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|other	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ZNF598		GO:0072344	rescue of stalled cytosolic ribosome	already_in_goa_exact	ok_for_propagation_to_go	translation.yaml	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	Translation|Cytosolic translation|Ribosome-associated QC|Ribosomal rescue	GTPBP1;GTPBP2;HBS1L;PELO;RACK1	GO:0072344 rescue of stalled cytosolic ribosome	1
ZNFX1		GO:0061630	ubiquitin protein ligase activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RZ	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RZ|RNA helicase	RNF213;ZNFX1		1
ZNRF1		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ZNRF|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / ZNRF|UBZ (ZNRF1/2)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
ZNRF2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ZNRF|other;Ubiquitin Proteasome System|Ubiquitin and UBL binding|E3 ligase|RING / ZNRF|UBZ (ZNRF1/2)	ASB2;FBXW4;FBXW7;FBXW8;MID1;MID2;PML;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	2
ZNRF3		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|ZNRF|transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ZNRF4		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|Goliath|PA, transmembrane	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ZRANB2		GO:0048024	regulation of mRNA splicing, via spliceosome	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing	Ubiquitin Proteasome System|Ubiquitin and UBL binding|mRNA maturation|mRNA splicing|RanBP2-type ZnF	RBM10;RBM44;RBM5;RBM6;ZRANB2		1
ZRANB3		GO:0006260	DNA replication	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication	Ubiquitin Proteasome System|Ubiquitin and UBL binding|DNA replication|DNE endonuclease and helicase|RanBP2-type ZnF	RFC1;WRNIP1;ZRANB3	GO:0031297 replication fork processing;GO:0071932 replication fork reversal	1
ZSWIM2		GO:0061630	ubiquitin protein ligase activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|RING|other|SWIM-type ZnF	MID1;MID2;TRIM36;TRIM46;TRIM9	GO:0061630 ubiquitin protein ligase activity	1
ZSWIM4		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor|VHL box|ZSWIM	ZER1;ZSWIM4;ZSWIM5;ZSWIM6;ZSWIM8		1
ZSWIM5		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor|VHL box|ZSWIM	ZER1;ZSWIM4;ZSWIM5;ZSWIM6;ZSWIM8		1
ZSWIM6		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor|VHL box|ZSWIM	ZER1;ZSWIM4;ZSWIM5;ZSWIM6;ZSWIM8		1
ZSWIM8		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	already_in_goa_exact	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate adaptor|VHL box|ZSWIM	ZER1;ZSWIM4;ZSWIM5;ZSWIM6;ZSWIM8	GO:1990756 ubiquitin-like ligase-substrate adaptor activity	1
ZUP1		GO:0101005	deubiquitinase activity	entailed_by_goa_closure	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|DUBs and UBL demodifiers|ZUP1	Ubiquitin Proteasome System|DUBs and UBL demodifiers|ZUP1|DUB	ZUP1	GO:0004843 cysteine-type deubiquitinase activity	1
ZYG11A		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|ZER1 group / Armadillo-like	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1
ZYG11B		GO:1990756	ubiquitin-like ligase-substrate adaptor activity	new_to_goa	ok_for_propagation_to_go	ubiquitin_proteasome_system.yaml	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor	Ubiquitin Proteasome System|E3 ubiquitin and UBL ligases|Cul2 substrate receptor|VHL box|ZER1 group / Armadillo-like, LRR	APPBP2;FEM1A;FEM1B;FEM1C;VHL		1