{
  "date": "2026-09-21",
  "target": "UniProtKB:A0BFB4",
  "limitations": "This records actual IBD and propagated target assertions plus live classification, not an independent reconstruction of the family tree or proof of functional loss.",
  "ibd": [
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0010506",
      "GO_REF:0000033",
      "IBD",
      "RGD:1589743|UniProtKB:O75385|FB:FBgn0037679|MGI:MGI:1270126",
      "P",
      "",
      "",
      "protein",
      "taxon:2759",
      "20241120",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0016020",
      "GO_REF:0000033",
      "IBD",
      "PomBase:SPCC63.08c|MGI:MGI:1352758|MGI:MGI:1270126|UniProtKB:Q8IYT8|UniProtKB:O75385|SGD:S000003148",
      "C",
      "",
      "",
      "protein",
      "taxon:2759",
      "20251220",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0005776",
      "GO_REF:0000033",
      "IBD",
      "FB:FBgn0037679|UniProtKB:Q4WPF2|AGI_LocusCode:AT3G61960|UniProtKB:O75385|SGD:S000003148|CGD:CAL0000188572",
      "C",
      "",
      "",
      "protein",
      "taxon:2759",
      "20240206",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0005829",
      "GO_REF:0000033",
      "IBD",
      "UniProtKB:O75385|SGD:S000003148|MGI:MGI:1270126",
      "C",
      "",
      "",
      "protein",
      "taxon:2759",
      "20221008",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0000407",
      "GO_REF:0000033",
      "IBD",
      "MGI:MGI:1270126|MGI:MGI:1352758|SGD:S000003148|UniProtKB:Q8IYT8|CGD:CAL0000188572|PomBase:SPCC63.08c|UniProtKB:O75385",
      "C",
      "",
      "",
      "protein",
      "taxon:2759",
      "20240206",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN002805221",
      "PTN002805221",
      "",
      "GO:0004674",
      "GO_REF:0000033",
      "IBD",
      "UniProtKB:Q8IYT8|FB:FBgn0260945|SGD:S000003148|MGI:MGI:1352758|MGI:MGI:1270126|WB:WBGene00006786|UniProtKB:O75385|PomBase:SPCC63.08c|UniProtKB:Q6PHR2",
      "F",
      "",
      "",
      "protein",
      "taxon:",
      "20231109",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN000681272",
      "PTN000681272",
      "",
      "GO:0000045",
      "GO_REF:0000033",
      "IBD",
      "UniProtKB:O75385|SGD:S000003148|FB:FBgn0260945|MGI:MGI:1270126",
      "P",
      "",
      "",
      "protein",
      "taxon:2759",
      "20241120",
      "GO_Central"
    ],
    [
      "PANTHER",
      "PTN002805221",
      "PTN002805221",
      "",
      "GO:0005737",
      "GO_REF:0000033",
      "IBD",
      "dictyBase:DDB_G0292390|MGI:MGI:1352758|FB:FBgn0260945|SGD:S000003148|UniProtKB:Q4WPF2|MGI:MGI:1270126|UniProtKB:Q8IYT8|AGI_LocusCode:AT3G61960|PomBase:SPCC63.08c|CGD:CAL0000188572|UniProtKB:Q6PHR2|UniProtKB:Q38BR3|FB:FBgn0037679|UniProtKB:O75385",
      "C",
      "",
      "",
      "protein",
      "taxon:",
      "20250903",
      "GO_Central"
    ]
  ],
  "target_paint_rows": [
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "is_active_in",
      "GO:0016020",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|MGI:MGI:1352758|MGI:MGI:1270126|UniProtKB:O75385|PomBase:SPCC63.08c|SGD:S000003148|UniProtKB:Q8IYT8",
      "C",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20251220",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "involved_in",
      "GO:0010506",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|UniProtKB:O75385|FB:FBgn0037679|RGD:1589743|MGI:MGI:1270126",
      "P",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20241120",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "is_active_in",
      "GO:0000407",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|MGI:MGI:1270126|MGI:MGI:1352758|CGD:CAL0000188572|PomBase:SPCC63.08c|UniProtKB:Q8IYT8|UniProtKB:O75385|SGD:S000003148",
      "C",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20240206",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "is_active_in",
      "GO:0005829",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|SGD:S000003148|UniProtKB:O75385|MGI:MGI:1270126",
      "C",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20221008",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "is_active_in",
      "GO:0005737",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN002805221|SGD:S000003148|UniProtKB:Q8IYT8|UniProtKB:Q38BR3|PomBase:SPCC63.08c|UniProtKB:Q6PHR2|MGI:MGI:1270126|FB:FBgn0260945|AGI_LocusCode:AT3G61960|MGI:MGI:1352758|dictyBase:DDB_G0292390|UniProtKB:Q4WPF2|CGD:CAL0000188572|FB:FBgn0037679|UniProtKB:O75385",
      "C",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20250903",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "enables",
      "GO:0004674",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN002805221|WB:WBGene00006786|SGD:S000003148|UniProtKB:Q8IYT8|PomBase:SPCC63.08c|UniProtKB:O75385|MGI:MGI:1352758|UniProtKB:Q6PHR2|MGI:MGI:1270126|FB:FBgn0260945",
      "F",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20231109",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "is_active_in",
      "GO:0005776",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|FB:FBgn0037679|UniProtKB:O75385|AGI_LocusCode:AT3G61960|SGD:S000003148|UniProtKB:Q4WPF2|CGD:CAL0000188572",
      "C",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20240206",
      "GO_Central"
    ],
    [
      "UniProtKB",
      "A0BFB4",
      "GSPATT00028266001",
      "involved_in",
      "GO:0000045",
      "GO_REF:0000033",
      "IBA",
      "PANTHER:PTN000681272|FB:FBgn0260945|MGI:MGI:1270126|UniProtKB:O75385|SGD:S000003148",
      "P",
      "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
      "UniProtKB:A0BFB4|PTN002805316",
      "protein",
      "taxon:5888",
      "20241120",
      "GO_Central"
    ]
  ],
  "family_ibd_rows": [
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0000407",
      "aspect": "C",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "CGD:CAL0000188572|MGI:MGI:1270126|MGI:MGI:1352758|PomBase:SPCC63.08c|SGD:S000003148|UniProtKB:O75385|UniProtKB:Q8IYT8",
      "taxon": "taxon:2759",
      "date": "20240206"
    },
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0005776",
      "aspect": "C",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "AGI_LocusCode:AT3G61960|CGD:CAL0000188572|FB:FBgn0037679|SGD:S000003148|UniProtKB:O75385|UniProtKB:Q4WPF2",
      "taxon": "taxon:2759",
      "date": "20240206"
    },
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0005829",
      "aspect": "C",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "MGI:MGI:1270126|SGD:S000003148|UniProtKB:O75385",
      "taxon": "taxon:2759",
      "date": "20221008"
    },
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0016020",
      "aspect": "C",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "MGI:MGI:1270126|MGI:MGI:1352758|PomBase:SPCC63.08c|SGD:S000003148|UniProtKB:O75385|UniProtKB:Q8IYT8",
      "taxon": "taxon:2759",
      "date": "20251220"
    },
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0000045",
      "aspect": "P",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "FB:FBgn0260945|MGI:MGI:1270126|SGD:S000003148|UniProtKB:O75385",
      "taxon": "taxon:2759",
      "date": "20241120"
    },
    {
      "family": "PTHR24348",
      "node": "PTN000681272",
      "go_id": "GO:0010506",
      "aspect": "P",
      "evidence": "IBD",
      "negated": "false",
      "seeds": "FB:FBgn0037679|MGI:MGI:1270126|RGD:1589743|UniProtKB:O75385",
      "taxon": "taxon:2759",
      "date": "20241120"
    }
  ],
  "live_uniprot": {
    "url": "https://rest.uniprot.org/uniprotkb/A0BFB4.json",
    "entryAudit": {
      "firstPublicDate": "2006-11-28",
      "lastAnnotationUpdateDate": "2026-09-02",
      "lastSequenceUpdateDate": "2006-11-28",
      "entryVersion": 89,
      "sequenceVersion": 1
    },
    "crossReferences": [
      {
        "database": "PANTHER",
        "id": "PTHR44167",
        "properties": [
          {
            "key": "EntryName",
            "value": "OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"
          },
          {
            "key": "MatchStatus",
            "value": "1"
          }
        ]
      },
      {
        "database": "PANTHER",
        "id": "PTHR44167:SF18",
        "properties": [
          {
            "key": "EntryName",
            "value": "PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"
          },
          {
            "key": "MatchStatus",
            "value": "1"
          }
        ]
      }
    ]
  },
  "live_interpro": {
    "url": "https://www.ebi.ac.uk/interpro/api/entry/panther/protein/uniprot/A0BFB4/",
    "data": {
      "count": 1,
      "next": null,
      "previous": null,
      "results": [
        {
          "metadata": {
            "accession": "PTHR44167",
            "name": "Serine/Threonine Protein Kinase",
            "source_database": "panther",
            "type": "family",
            "integrated": null,
            "member_databases": null,
            "go_terms": null
          },
          "proteins": [
            {
              "accession": "a0bfb4",
              "protein_length": 381,
              "source_database": "unreviewed",
              "organism": "5888",
              "in_alphafold": true,
              "entry_protein_locations": [
                {
                  "fragments": [
                    {
                      "start": 70,
                      "end": 348,
                      "dc-status": "CONTINUOUS"
                    }
                  ],
                  "representative": true,
                  "model": "PTHR44167:SF18",
                  "score": 7.6e-61,
                  "subfamily": {
                    "accession": "PTHR44167:SF18",
                    "name": "PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"
                  }
                }
              ]
            }
          ]
        }
      ]
    }
  },
  "tree_access": "Successful POST to https://www.pantherdb.org/services/oai/pantherdb/treeinfo with form family=PTHR24348. Read actual nested annotation_node path; full response hash and lineage retained below.",
  "tree_sha256": "4805ff91415980ecd8d69c9bb059654ac3b6c409ef07f4f4445f5a0ba41101ef",
  "tree_search_parameters": {
    "family": "PTHR24348"
  },
  "tree_target_lineages": [
    [
      {
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;",
        "event_type": "DUPLICATION",
        "persistent_id": "PTN002805221",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;",
        "tree_node_type": "ROOT",
        "branch_length": 0,
        "taxonomic_range": "Eukaryota",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;",
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;"
      },
      {
        "sf_id": "PTHR24348:SF22",
        "persistent_id": "PTN000681272",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "branch_length": 0.461,
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;",
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;",
        "prop_sf_id": "PTHR24348:SF22",
        "event_type": "SPECIATION",
        "species": "Eukaryota",
        "tree_node_type": "INTERNAL",
        "taxonomic_range": "Eukaryota",
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;"
      },
      {
        "persistent_id": "PTN007795585",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "branch_length": 0.106,
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;",
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;(REVIEWED)-GO:0034727=piecemeal microautophagy of the nucleus;(REVIEWED)-GO:0000422=autophagy of mitochondrion;(REVIEWED)-GO:0007005=mitochondrion organization;(REVIEWED)-GO:0022411=cellular component disassembly;(REVIEWED)-GO:0031667=response to nutrient levels;(REVIEWED)-GO:0009991=response to extracellular stimulus;(REVIEWED)-GO:0050896=response to stimulus;(REVIEWED)-GO:0016237=microautophagy;(REVIEWED)-GO:0042594=response to starvation;(REVIEWED)-GO:0061709=reticulophagy;(REVIEWED)-GO:0009605=response to external stimulus;(REVIEWED)-GO:0006950=response to stress;(REVIEWED)-GO:1903008=organelle disassembly;(REVIEWED)-GO:0048731=system development;(REVIEWED)-GO:0030154=cell differentiation;(REVIEWED)-GO:0032502=developmental process;(REVIEWED)-GO:0032501=multicellular organismal process;(REVIEWED)-GO:0031325=positive regulation of cellular metabolic process;(REVIEWED)-GO:0048858=cell projection morphogenesis;(REVIEWED)-GO:0048856=anatomical structure development;(REVIEWED)-GO:0048468=cell development;(REVIEWED)-GO:0009896=positive regulation of catabolic process;(REVIEWED)-GO:0016049=cell growth;(REVIEWED)-GO:0009893=positive regulation of metabolic process;(REVIEWED)-GO:0060560=developmental growth involved in morphogenesis;(REVIEWED)-GO:0040007=growth;(REVIEWED)-GO:0120039=plasma membrane bounded cell projection morphogenesis;(REVIEWED)-GO:0048589=developmental growth;(REVIEWED)-GO:0048588=developmental cell growth;(REVIEWED)-GO:0120036=plasma membrane bounded cell projection organization;(REVIEWED)-GO:0000902=cell morphogenesis;(REVIEWED)-GO:0048522=positive regulation of cellular process;(REVIEWED)-GO:0010508=positive regulation of autophagy;(REVIEWED)-GO:0030030=cell projection organization;(REVIEWED)-GO:0048518=positive regulation of biological process;(REVIEWED)-GO:0048869=cellular developmental process;(REVIEWED)-GO:0032989=cellular anatomical entity morphogenesis;(REVIEWED)-GO:0031331=positive regulation of cellular catabolic process;(REVIEWED)-GO:0007275=multicellular organism development;(REVIEWED)-GO:0009653=anatomical structure morphogenesis;(REVIEWED)-GO:0050767=regulation of neurogenesis;(REVIEWED)-GO:0008361=regulation of cell size;(REVIEWED)-GO:0010975=regulation of neuron projection development;(REVIEWED)-GO:2000026=regulation of multicellular organismal development;(REVIEWED)-GO:0045595=regulation of cell differentiation;(REVIEWED)-GO:0031344=regulation of cell projection organization;(REVIEWED)-GO:0050793=regulation of developmental process;(REVIEWED)-GO:0048523=negative regulation of cellular process;(REVIEWED)-GO:0051239=regulation of multicellular organismal process;(REVIEWED)-GO:0051960=regulation of nervous system development;(REVIEWED)-GO:0120035=regulation of plasma membrane bounded cell projection organization;(REVIEWED)-GO:0065008=regulation of biological quality;(REVIEWED)-GO:0051129=negative regulation of cellular component organization;(REVIEWED)-GO:0051128=regulation of cellular component organization;(REVIEWED)-GO:0040008=regulation of growth;(REVIEWED)-GO:0050770=regulation of axonogenesis;(REVIEWED)-GO:0060284=regulation of cell development;(REVIEWED)-GO:0001558=regulation of cell growth;(REVIEWED)-GO:0090066=regulation of anatomical structure size;(REVIEWED)-GO:0048519=negative regulation of biological process;(REVIEWED)-GO:0051241=negative regulation of multicellular organismal process;(REVIEWED)-GO:0022603=regulation of anatomical structure morphogenesis;(REVIEWED)-GO:0032535=regulation of cellular component size;",
        "prop_sf_id": "PTHR24348:SF22",
        "event_type": "SPECIATION",
        "species": "Bikonts",
        "tree_node_type": "INTERNAL",
        "taxonomic_range": "Bikonts",
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;"
      },
      {
        "persistent_id": "PTN008401646",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "branch_length": 0.18,
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;",
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;(REVIEWED)-GO:0034727=piecemeal microautophagy of the nucleus;(REVIEWED)-GO:0000422=autophagy of mitochondrion;(REVIEWED)-GO:0007005=mitochondrion organization;(REVIEWED)-GO:0022411=cellular component disassembly;(REVIEWED)-GO:0031667=response to nutrient levels;(REVIEWED)-GO:0009991=response to extracellular stimulus;(REVIEWED)-GO:0050896=response to stimulus;(REVIEWED)-GO:0016237=microautophagy;(REVIEWED)-GO:0042594=response to starvation;(REVIEWED)-GO:0061709=reticulophagy;(REVIEWED)-GO:0009605=response to external stimulus;(REVIEWED)-GO:0006950=response to stress;(REVIEWED)-GO:1903008=organelle disassembly;(REVIEWED)-GO:0048731=system development;(REVIEWED)-GO:0030154=cell differentiation;(REVIEWED)-GO:0032502=developmental process;(REVIEWED)-GO:0032501=multicellular organismal process;(REVIEWED)-GO:0031325=positive regulation of cellular metabolic process;(REVIEWED)-GO:0048858=cell projection morphogenesis;(REVIEWED)-GO:0048856=anatomical structure development;(REVIEWED)-GO:0048468=cell development;(REVIEWED)-GO:0009896=positive regulation of catabolic process;(REVIEWED)-GO:0016049=cell growth;(REVIEWED)-GO:0009893=positive regulation of metabolic process;(REVIEWED)-GO:0060560=developmental growth involved in morphogenesis;(REVIEWED)-GO:0040007=growth;(REVIEWED)-GO:0120039=plasma membrane bounded cell projection morphogenesis;(REVIEWED)-GO:0048589=developmental growth;(REVIEWED)-GO:0048588=developmental cell growth;(REVIEWED)-GO:0120036=plasma membrane bounded cell projection organization;(REVIEWED)-GO:0000902=cell morphogenesis;(REVIEWED)-GO:0048522=positive regulation of cellular process;(REVIEWED)-GO:0010508=positive regulation of autophagy;(REVIEWED)-GO:0030030=cell projection organization;(REVIEWED)-GO:0048518=positive regulation of biological process;(REVIEWED)-GO:0048869=cellular developmental process;(REVIEWED)-GO:0032989=cellular anatomical entity morphogenesis;(REVIEWED)-GO:0031331=positive regulation of cellular catabolic process;(REVIEWED)-GO:0007275=multicellular organism development;(REVIEWED)-GO:0009653=anatomical structure morphogenesis;(REVIEWED)-GO:0050767=regulation of neurogenesis;(REVIEWED)-GO:0008361=regulation of cell size;(REVIEWED)-GO:0010975=regulation of neuron projection development;(REVIEWED)-GO:2000026=regulation of multicellular organismal development;(REVIEWED)-GO:0045595=regulation of cell differentiation;(REVIEWED)-GO:0031344=regulation of cell projection organization;(REVIEWED)-GO:0050793=regulation of developmental process;(REVIEWED)-GO:0048523=negative regulation of cellular process;(REVIEWED)-GO:0051239=regulation of multicellular organismal process;(REVIEWED)-GO:0051960=regulation of nervous system development;(REVIEWED)-GO:0120035=regulation of plasma membrane bounded cell projection organization;(REVIEWED)-GO:0065008=regulation of biological quality;(REVIEWED)-GO:0051129=negative regulation of cellular component organization;(REVIEWED)-GO:0051128=regulation of cellular component organization;(REVIEWED)-GO:0040008=regulation of growth;(REVIEWED)-GO:0050770=regulation of axonogenesis;(REVIEWED)-GO:0060284=regulation of cell development;(REVIEWED)-GO:0001558=regulation of cell growth;(REVIEWED)-GO:0090066=regulation of anatomical structure size;(REVIEWED)-GO:0048519=negative regulation of biological process;(REVIEWED)-GO:0051241=negative regulation of multicellular organismal process;(REVIEWED)-GO:0022603=regulation of anatomical structure morphogenesis;(REVIEWED)-GO:0032535=regulation of cellular component size;",
        "prop_sf_id": "PTHR24348:SF22",
        "event_type": "SPECIATION",
        "species": "SAR/HA_supergroup",
        "tree_node_type": "INTERNAL",
        "taxonomic_range": "SAR/HA_supergroup",
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;"
      },
      {
        "persistent_id": "PTN001218730",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "branch_length": 0.696,
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;",
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;(REVIEWED)-GO:0034727=piecemeal microautophagy of the nucleus;(REVIEWED)-GO:0000422=autophagy of mitochondrion;(REVIEWED)-GO:0007005=mitochondrion organization;(REVIEWED)-GO:0022411=cellular component disassembly;(REVIEWED)-GO:0031667=response to nutrient levels;(REVIEWED)-GO:0009991=response to extracellular stimulus;(REVIEWED)-GO:0050896=response to stimulus;(REVIEWED)-GO:0016237=microautophagy;(REVIEWED)-GO:0042594=response to starvation;(REVIEWED)-GO:0061709=reticulophagy;(REVIEWED)-GO:0009605=response to external stimulus;(REVIEWED)-GO:0006950=response to stress;(REVIEWED)-GO:1903008=organelle disassembly;(REVIEWED)-GO:0048731=system development;(REVIEWED)-GO:0030154=cell differentiation;(REVIEWED)-GO:0032502=developmental process;(REVIEWED)-GO:0032501=multicellular organismal process;(REVIEWED)-GO:0031325=positive regulation of cellular metabolic process;(REVIEWED)-GO:0048858=cell projection morphogenesis;(REVIEWED)-GO:0048856=anatomical structure development;(REVIEWED)-GO:0048468=cell development;(REVIEWED)-GO:0009896=positive regulation of catabolic process;(REVIEWED)-GO:0016049=cell growth;(REVIEWED)-GO:0009893=positive regulation of metabolic process;(REVIEWED)-GO:0060560=developmental growth involved in morphogenesis;(REVIEWED)-GO:0040007=growth;(REVIEWED)-GO:0120039=plasma membrane bounded cell projection morphogenesis;(REVIEWED)-GO:0048589=developmental growth;(REVIEWED)-GO:0048588=developmental cell growth;(REVIEWED)-GO:0120036=plasma membrane bounded cell projection organization;(REVIEWED)-GO:0000902=cell morphogenesis;(REVIEWED)-GO:0048522=positive regulation of cellular process;(REVIEWED)-GO:0010508=positive regulation of autophagy;(REVIEWED)-GO:0030030=cell projection organization;(REVIEWED)-GO:0048518=positive regulation of biological process;(REVIEWED)-GO:0048869=cellular developmental process;(REVIEWED)-GO:0032989=cellular anatomical entity morphogenesis;(REVIEWED)-GO:0031331=positive regulation of cellular catabolic process;(REVIEWED)-GO:0007275=multicellular organism development;(REVIEWED)-GO:0009653=anatomical structure morphogenesis;(REVIEWED)-GO:0050767=regulation of neurogenesis;(REVIEWED)-GO:0008361=regulation of cell size;(REVIEWED)-GO:0010975=regulation of neuron projection development;(REVIEWED)-GO:2000026=regulation of multicellular organismal development;(REVIEWED)-GO:0045595=regulation of cell differentiation;(REVIEWED)-GO:0031344=regulation of cell projection organization;(REVIEWED)-GO:0050793=regulation of developmental process;(REVIEWED)-GO:0048523=negative regulation of cellular process;(REVIEWED)-GO:0051239=regulation of multicellular organismal process;(REVIEWED)-GO:0051960=regulation of nervous system development;(REVIEWED)-GO:0120035=regulation of plasma membrane bounded cell projection organization;(REVIEWED)-GO:0065008=regulation of biological quality;(REVIEWED)-GO:0051129=negative regulation of cellular component organization;(REVIEWED)-GO:0051128=regulation of cellular component organization;(REVIEWED)-GO:0040008=regulation of growth;(REVIEWED)-GO:0050770=regulation of axonogenesis;(REVIEWED)-GO:0060284=regulation of cell development;(REVIEWED)-GO:0001558=regulation of cell growth;(REVIEWED)-GO:0090066=regulation of anatomical structure size;(REVIEWED)-GO:0048519=negative regulation of biological process;(REVIEWED)-GO:0051241=negative regulation of multicellular organismal process;(REVIEWED)-GO:0022603=regulation of anatomical structure morphogenesis;(REVIEWED)-GO:0032535=regulation of cellular component size;",
        "prop_sf_id": "PTHR24348:SF22",
        "event_type": "SPECIATION",
        "species": "Alveolata-Stramenopiles",
        "tree_node_type": "INTERNAL",
        "taxonomic_range": "Alveolata-Stramenopiles",
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;"
      },
      {
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;(REVIEWED)-GO:0034727=piecemeal microautophagy of the nucleus;(REVIEWED)-GO:0000422=autophagy of mitochondrion;(REVIEWED)-GO:0007005=mitochondrion organization;(REVIEWED)-GO:0022411=cellular component disassembly;(REVIEWED)-GO:0031667=response to nutrient levels;(REVIEWED)-GO:0009991=response to extracellular stimulus;(REVIEWED)-GO:0050896=response to stimulus;(REVIEWED)-GO:0016237=microautophagy;(REVIEWED)-GO:0042594=response to starvation;(REVIEWED)-GO:0061709=reticulophagy;(REVIEWED)-GO:0009605=response to external stimulus;(REVIEWED)-GO:0006950=response to stress;(REVIEWED)-GO:1903008=organelle disassembly;(REVIEWED)-GO:0048731=system development;(REVIEWED)-GO:0030154=cell differentiation;(REVIEWED)-GO:0032502=developmental process;(REVIEWED)-GO:0032501=multicellular organismal process;(REVIEWED)-GO:0031325=positive regulation of cellular metabolic process;(REVIEWED)-GO:0048858=cell projection morphogenesis;(REVIEWED)-GO:0048856=anatomical structure development;(REVIEWED)-GO:0048468=cell development;(REVIEWED)-GO:0009896=positive regulation of catabolic process;(REVIEWED)-GO:0016049=cell growth;(REVIEWED)-GO:0009893=positive regulation of metabolic process;(REVIEWED)-GO:0060560=developmental growth involved in morphogenesis;(REVIEWED)-GO:0040007=growth;(REVIEWED)-GO:0120039=plasma membrane bounded cell projection morphogenesis;(REVIEWED)-GO:0048589=developmental growth;(REVIEWED)-GO:0048588=developmental cell growth;(REVIEWED)-GO:0120036=plasma membrane bounded cell projection organization;(REVIEWED)-GO:0000902=cell morphogenesis;(REVIEWED)-GO:0048522=positive regulation of cellular process;(REVIEWED)-GO:0010508=positive regulation of autophagy;(REVIEWED)-GO:0030030=cell projection organization;(REVIEWED)-GO:0048518=positive regulation of biological process;(REVIEWED)-GO:0048869=cellular developmental process;(REVIEWED)-GO:0032989=cellular anatomical entity morphogenesis;(REVIEWED)-GO:0031331=positive regulation of cellular catabolic process;(REVIEWED)-GO:0007275=multicellular organism development;(REVIEWED)-GO:0009653=anatomical structure morphogenesis;(REVIEWED)-GO:0050767=regulation of neurogenesis;(REVIEWED)-GO:0008361=regulation of cell size;(REVIEWED)-GO:0010975=regulation of neuron projection development;(REVIEWED)-GO:2000026=regulation of multicellular organismal development;(REVIEWED)-GO:0045595=regulation of cell differentiation;(REVIEWED)-GO:0031344=regulation of cell projection organization;(REVIEWED)-GO:0050793=regulation of developmental process;(REVIEWED)-GO:0048523=negative regulation of cellular process;(REVIEWED)-GO:0051239=regulation of multicellular organismal process;(REVIEWED)-GO:0051960=regulation of nervous system development;(REVIEWED)-GO:0120035=regulation of plasma membrane bounded cell projection organization;(REVIEWED)-GO:0065008=regulation of biological quality;(REVIEWED)-GO:0051129=negative regulation of cellular component organization;(REVIEWED)-GO:0051128=regulation of cellular component organization;(REVIEWED)-GO:0040008=regulation of growth;(REVIEWED)-GO:0050770=regulation of axonogenesis;(REVIEWED)-GO:0060284=regulation of cell development;(REVIEWED)-GO:0001558=regulation of cell growth;(REVIEWED)-GO:0090066=regulation of anatomical structure size;(REVIEWED)-GO:0048519=negative regulation of biological process;(REVIEWED)-GO:0051241=negative regulation of multicellular organismal process;(REVIEWED)-GO:0022603=regulation of anatomical structure morphogenesis;(REVIEWED)-GO:0032535=regulation of cellular component size;",
        "prop_sf_id": "PTHR24348:SF22",
        "event_type": "DUPLICATION",
        "persistent_id": "PTN007795752",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "tree_node_type": "INTERNAL",
        "branch_length": 0,
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;",
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;"
      },
      {
        "persistent_id": "PTN002805316",
        "organism": "Paramecium tetraurelia",
        "PANTHER_GO_SLIM_CC": "(REVIEWED)-GO:0110165=cellular anatomical entity;(REVIEWED)-GO:0005737=cytoplasm;(REVIEWED)-GO:0005622=intracellular anatomical structure;(REVIEWED)-GO:0005776=autophagosome;(REVIEWED)-GO:0000407=phagophore assembly site;(REVIEWED)-GO:0005773=vacuole;(REVIEWED)-GO:0016020=membrane;(REVIEWED)-GO:0043231=intracellular membrane-bounded organelle;(REVIEWED)-GO:0043229=intracellular organelle;(REVIEWED)-GO:0043227=membrane-bounded organelle;(REVIEWED)-GO:0005829=cytosol;(REVIEWED)-GO:0043226=organelle;",
        "gene_symbol": "GSPATT00028266001",
        "node_name": "PARTE|EnsemblGenome=GSPATT00028266001|UniProtKB=A0BFB4",
        "branch_length": 2,
        "PANTHER_GO_SLIM_MF": "(REVIEWED)-GO:0016301=kinase activity;(REVIEWED)-GO:0004672=protein kinase activity;(REVIEWED)-GO:0016740=transferase activity;(REVIEWED)-GO:0140096=catalytic activity, acting on a protein;(REVIEWED)-GO:0003824=catalytic activity;(REVIEWED)-GO:0016773=phosphotransferase activity, alcohol group as acceptor;(REVIEWED)-GO:0016772=transferase activity, transferring phosphorus-containing groups;(REVIEWED)-GO:0004674=protein serine/threonine kinase activity;",
        "PANTHER_GO_SLIM_BP": "(REVIEWED)-GO:0043170=macromolecule metabolic process;(REVIEWED)-GO:0009987=cellular process;(REVIEWED)-GO:0006468=protein phosphorylation;(REVIEWED)-GO:0044238=primary metabolic process;(REVIEWED)-GO:0044237=cellular metabolic process;(REVIEWED)-GO:0036211=protein modification process;(REVIEWED)-GO:0006807=nitrogen compound metabolic process;(REVIEWED)-GO:0018105=peptidyl-serine phosphorylation;(REVIEWED)-GO:0071704=organic substance metabolic process;(REVIEWED)-GO:0018193=peptidyl-amino acid modification;(REVIEWED)-GO:0008152=metabolic process;(REVIEWED)-GO:0043412=macromolecule modification;(REVIEWED)-GO:1901564=organonitrogen compound metabolic process;(REVIEWED)-GO:0016310=phosphorylation;(REVIEWED)-GO:0019538=protein metabolic process;(REVIEWED)-GO:0006796=phosphate-containing compound metabolic process;(REVIEWED)-GO:0018209=peptidyl-serine modification;(REVIEWED)-GO:0006793=phosphorus metabolic process;(REVIEWED)-GO:0006996=organelle organization;(REVIEWED)-GO:0031329=regulation of cellular catabolic process;(REVIEWED)-GO:0022607=cellular component assembly;(REVIEWED)-GO:0019222=regulation of metabolic process;(REVIEWED)-GO:0031323=regulation of cellular metabolic process;(REVIEWED)-GO:0000045=autophagosome assembly;(REVIEWED)-GO:0009894=regulation of catabolic process;(REVIEWED)-GO:0050794=regulation of cellular process;(REVIEWED)-GO:0016043=cellular component organization;(REVIEWED)-GO:0007033=vacuole organization;(REVIEWED)-GO:0044085=cellular component biogenesis;(REVIEWED)-GO:0016236=macroautophagy;(REVIEWED)-GO:0044248=cellular catabolic process;(REVIEWED)-GO:0009056=catabolic process;(REVIEWED)-GO:0006914=autophagy;(REVIEWED)-GO:0010506=regulation of autophagy;(REVIEWED)-GO:0050789=regulation of biological process;(REVIEWED)-GO:0071840=cellular component organization or biogenesis;(REVIEWED)-GO:0061919=process utilizing autophagic mechanism;(REVIEWED)-GO:0065007=biological regulation;(REVIEWED)-GO:0070925=organelle assembly;(REVIEWED)-GO:0034727=piecemeal microautophagy of the nucleus;(REVIEWED)-GO:0000422=autophagy of mitochondrion;(REVIEWED)-GO:0007005=mitochondrion organization;(REVIEWED)-GO:0022411=cellular component disassembly;(REVIEWED)-GO:0031667=response to nutrient levels;(REVIEWED)-GO:0009991=response to extracellular stimulus;(REVIEWED)-GO:0050896=response to stimulus;(REVIEWED)-GO:0016237=microautophagy;(REVIEWED)-GO:0042594=response to starvation;(REVIEWED)-GO:0061709=reticulophagy;(REVIEWED)-GO:0009605=response to external stimulus;(REVIEWED)-GO:0006950=response to stress;(REVIEWED)-GO:1903008=organelle disassembly;(REVIEWED)-GO:0048731=system development;(REVIEWED)-GO:0030154=cell differentiation;(REVIEWED)-GO:0032502=developmental process;(REVIEWED)-GO:0032501=multicellular organismal process;(REVIEWED)-GO:0031325=positive regulation of cellular metabolic process;(REVIEWED)-GO:0048858=cell projection morphogenesis;(REVIEWED)-GO:0048856=anatomical structure development;(REVIEWED)-GO:0048468=cell development;(REVIEWED)-GO:0009896=positive regulation of catabolic process;(REVIEWED)-GO:0016049=cell growth;(REVIEWED)-GO:0009893=positive regulation of metabolic process;(REVIEWED)-GO:0060560=developmental growth involved in morphogenesis;(REVIEWED)-GO:0040007=growth;(REVIEWED)-GO:0120039=plasma membrane bounded cell projection morphogenesis;(REVIEWED)-GO:0048589=developmental growth;(REVIEWED)-GO:0048588=developmental cell growth;(REVIEWED)-GO:0120036=plasma membrane bounded cell projection organization;(REVIEWED)-GO:0000902=cell morphogenesis;(REVIEWED)-GO:0048522=positive regulation of cellular process;(REVIEWED)-GO:0010508=positive regulation of autophagy;(REVIEWED)-GO:0030030=cell projection organization;(REVIEWED)-GO:0048518=positive regulation of biological process;(REVIEWED)-GO:0048869=cellular developmental process;(REVIEWED)-GO:0032989=cellular anatomical entity morphogenesis;(REVIEWED)-GO:0031331=positive regulation of cellular catabolic process;(REVIEWED)-GO:0007275=multicellular organism development;(REVIEWED)-GO:0009653=anatomical structure morphogenesis;(REVIEWED)-GO:0050767=regulation of neurogenesis;(REVIEWED)-GO:0008361=regulation of cell size;(REVIEWED)-GO:0010975=regulation of neuron projection development;(REVIEWED)-GO:2000026=regulation of multicellular organismal development;(REVIEWED)-GO:0045595=regulation of cell differentiation;(REVIEWED)-GO:0031344=regulation of cell projection organization;(REVIEWED)-GO:0050793=regulation of developmental process;(REVIEWED)-GO:0048523=negative regulation of cellular process;(REVIEWED)-GO:0051239=regulation of multicellular organismal process;(REVIEWED)-GO:0051960=regulation of nervous system development;(REVIEWED)-GO:0120035=regulation of plasma membrane bounded cell projection organization;(REVIEWED)-GO:0065008=regulation of biological quality;(REVIEWED)-GO:0051129=negative regulation of cellular component organization;(REVIEWED)-GO:0051128=regulation of cellular component organization;(REVIEWED)-GO:0040008=regulation of growth;(REVIEWED)-GO:0050770=regulation of axonogenesis;(REVIEWED)-GO:0060284=regulation of cell development;(REVIEWED)-GO:0001558=regulation of cell growth;(REVIEWED)-GO:0090066=regulation of anatomical structure size;(REVIEWED)-GO:0048519=negative regulation of biological process;(REVIEWED)-GO:0051241=negative regulation of multicellular organismal process;(REVIEWED)-GO:0022603=regulation of anatomical structure morphogenesis;(REVIEWED)-GO:0032535=regulation of cellular component size;",
        "prop_sf_id": "PTHR24348:SF22",
        "tree_node_type": "LEAF",
        "definition": "Chromosome undetermined scaffold_103, whole genome shotgun sequence",
        "gene_id": "EnsemblGenome:GSPATT00028266001",
        "sf_name": "NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE",
        "PANTHER_PC": "(REVIEWED)-PC00167=non-receptor serine/threonine protein kinase;"
      }
    ]
  ],
  "other_tree_check": {
    "family": "PTHR44167",
    "url": "https://www.pantherdb.org/services/oai/pantherdb/treeinfo",
    "sha256": "f7f4e07f4eb029670b421a0a801e77631e427a833d52db4e7400a156e00d075c",
    "target_accession_present": false,
    "target_leaf_ptn_present": false
  }
}