View original ARBA rule on UniProt
ARBA rule assigning GO:0016740 transferase activity through 1340 alternative condition sets built from InterPro, CATH FunFam, PANTHER and taxon conditions.
Condition-set counts describe the sets recorded in this review, which may omit the full rule.
No domain overlap table is shown: the cached overlap analysis for this version of the review is not available.
Run just analyze-rule ARBA00027723 and re-render to add it.
The live rule has 1340 condition sets, 227 of which carry a taxon condition. No condition set was examined against annotated proteins, so none is recorded here and no verdict is given. The term is the general parent of all transferase activities; that makes the annotation uninformative where a specific activity is known, not wrong.
None of the 1340 condition sets was examined, and no wrongly annotated protein is known.
No matched protein was checked. IPR000014 (PAS domain) does not occur in any condition set of the rule retrieved on 2026-11-09.
id: ARBA00027723
description: >-
ARBA rule assigning GO:0016740 transferase activity through 1340 alternative condition sets built
from InterPro, CATH FunFam, PANTHER and taxon conditions.
status: IN_PROGRESS
rule_type: ARBA
rule:
rule_id: ARBA00027723
condition_sets: []
go_annotations:
- go_id: GO:0016740
go_label: transferase activity
aspect: MF
entries: []
reviewed_protein_count: 0
unreviewed_protein_count: 0
created_date: '2021-10-20'
modified_date: '2026-07-18'
retrieved_date: '2026-11-09'
source_condition_set_count: 1340
review_summary: >-
The live rule has 1340 condition sets, 227 of which carry a taxon condition. No condition set was
examined against annotated proteins, so none is recorded here and no verdict is given. The term
is the general parent of all transferase activities; that makes the annotation uninformative where
a specific activity is known, not wrong.
action: UNDECIDED
action_rationale: None of the 1340 condition sets was examined, and no wrongly annotated protein is
known.
suggested_modifications:
- >-
Examine a sample of condition sets against curated molecular function annotations of their Swiss-Prot
members.
annotation_assessments:
- annotation_kind: GO_TERM
value: GO:0016740
label: transferase activity
assessment: UNDECIDED
notes: >-
No matched protein was checked. IPR000014 (PAS domain) does not occur in any condition set of
the rule retrieved on 2026-11-09.
corrections:
- date: '2026-11-10'
withdrawn_claim: The rule erroneously includes the non-transferase PAS domain IPR000014.
correction: >-
IPR000014 is not in any of the 1340 live condition sets. Whether an earlier version used it, and
with which other conditions, could not be checked.
error_type: STALE_RULE_VERSION
evidence:
- 'rest.uniprot.org/arba/ARBA00027723, modified 2026-07-18: no condition with value IPR000014'
- date: '2026-11-10'
withdrawn_claim: The rule lacks taxonomic restrictions.
correction: 227 of the 1340 live condition sets carry a taxon condition.
error_type: TAXON_MISREAD
evidence:
- Count over conditionSets of rest.uniprot.org/arba/ARBA00027723, 2026-11-09
- date: '2026-11-10'
withdrawn_claim: >-
1094 condition sets exceed a limit of 12 by two orders of magnitude, so the rule should be deprecated.
correction: Rule size is not evidence about correctness.
error_type: SIZE_AS_EVIDENCE
evidence:
- No protein-level evidence was given
- date: '2026-11-10'
withdrawn_claim: GO:0016740 is too broad, so the rule should be deprecated.
correction: A general term that is true of the matched proteins is not an error.
error_type: GENERAL_IS_NOT_WRONG
evidence:
- GO:0016740 transferase activity is the parent of all EC 2 activities
- date: '2026-11-10'
withdrawn_claim: Condition overlap is complete.
correction: No overlap was measured; the assessment is removed.
error_type: UNEXAMINED_RULE
evidence:
- 'Previous file recorded condition_sets: []'