mitfa / mitfb: annotation comparison
Generated by projects/DANRE_DUPLICATION/scripts/compare_pair.py; do not edit by hand.
Proteins
| mitfa | mitfb | |
|---|---|---|
| UniProt | Q9PWC2 | F1Q885 |
| Length (aa) | 412 | 500 |
Global alignment (BLOSUM62, gap -10/-0.5): 55.0% identity, 64.7% similarity over 515 alignment columns.
Existing annotations by term
Cells show evidence:action. — means the copy has no annotation to that exact term (it may still have a parent or child term).
MF
| Term | mitfa | mitfb |
|---|---|---|
| GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding | IBA:ACCEPT | IBA:ACCEPT |
| GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific | IBA:ACCEPT IDA:ACCEPT |
IBA:ACCEPT IDA:ACCEPT |
| GO:0046983 protein dimerization activity | IEA:KEEP_AS_NON_CORE | IEA:KEEP_AS_NON_CORE |
BP
| Term | mitfa | mitfb |
|---|---|---|
| GO:0006351 DNA-templated transcription | IDA:MODIFY | IDA:MODIFY |
| GO:0006355 regulation of DNA-templated transcription | IEA:ACCEPT | IEA:ACCEPT |
| GO:0006357 regulation of transcription by RNA polymerase II | IBA:ACCEPT | IBA:ACCEPT |
| GO:0007623 circadian rhythm | IDA:UNDECIDED | — |
| GO:0030318 melanocyte differentiation | IBA:ACCEPT IGI:ACCEPT IMP:ACCEPT |
IBA:KEEP_AS_NON_CORE IGI:KEEP_AS_NON_CORE |
| GO:0043473 pigmentation | IGI:KEEP_AS_NON_CORE IMP:KEEP_AS_NON_CORE |
— |
| GO:0045636 positive regulation of melanocyte differentiation | IMP:ACCEPT | — |
| GO:0050936 xanthophore differentiation | IGI:NEW | IGI:NEW |
| GO:0061386 closure of optic fissure | IGI:KEEP_AS_NON_CORE | — |
| GO:0071228 cellular response to tumor cell | IMP:REMOVE | — |
CC
| Term | mitfa | mitfb |
|---|---|---|
| GO:0005634 nucleus | IBA:ACCEPT IEA:ACCEPT |
IBA:ACCEPT IEA:ACCEPT |
| GO:0005654 nucleoplasm | IC:ACCEPT | IC:ACCEPT |
| GO:0005737 cytoplasm | IEA:KEEP_AS_NON_CORE | IEA:KEEP_AS_NON_CORE |
Core molecular functions
- mitfa: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
- mitfb: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific