tbx5a / tbx5b: annotation comparison
Generated by projects/DANRE_DUPLICATION/scripts/compare_pair.py; do not edit by hand.
Proteins
| tbx5a | tbx5b | |
|---|---|---|
| UniProt | Q9IAK8 | E3W6T6 |
| Length (aa) | 492 | 422 |
Global alignment (BLOSUM62, gap -10/-0.5): 49.2% identity, 58.7% similarity over 504 alignment columns.
Existing annotations by term
Cells show evidence:action. — means the copy has no annotation to that exact term (it may still have a parent or child term).
MF
| Term | tbx5a | tbx5b |
|---|---|---|
| GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding | IBA:ACCEPT IEA:ACCEPT ISS:ACCEPT |
IBA:ACCEPT IEA:ACCEPT |
| GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific | IBA:ACCEPT ISS:ACCEPT |
IBA:ACCEPT |
| GO:0003677 DNA binding | — | IEA:ACCEPT |
| GO:0003700 DNA-binding transcription factor activity | IDA:ACCEPT IEA:ACCEPT |
IEA:ACCEPT |
| GO:0005515 protein binding | IPI:REMOVE | — |
| GO:0043565 sequence-specific DNA binding | IDA:ACCEPT | — |
| GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding | IPI:UNDECIDED | — |
BP
| Term | tbx5a | tbx5b |
|---|---|---|
| GO:0001708 cell fate specification | IBA:KEEP_AS_NON_CORE | IBA:KEEP_AS_NON_CORE |
| GO:0001947 heart looping | IGI:ACCEPT IMP:ACCEPT |
IGI:ACCEPT IMP:ACCEPT |
| GO:0003007 heart morphogenesis | IGI:ACCEPT IMP:ACCEPT |
IMP:ACCEPT |
| GO:0003143 embryonic heart tube morphogenesis | IGI:ACCEPT IMP:ACCEPT |
— |
| GO:0003146 heart jogging | IGI:UNDECIDED IMP:UNDECIDED |
IGI:KEEP_AS_NON_CORE IMP:KEEP_AS_NON_CORE |
| GO:0003190 atrioventricular valve formation | IMP:KEEP_AS_NON_CORE | — |
| GO:0003206 cardiac chamber morphogenesis | IMP:ACCEPT | — |
| GO:0003218 cardiac left ventricle formation | IBA:MARK_AS_OVER_ANNOTATED | IBA:MARK_AS_OVER_ANNOTATED |
| GO:0003294 atrial ventricular junction remodeling | IMP:KEEP_AS_NON_CORE | — |
| GO:0003342 proepicardium development | IMP:ACCEPT | — |
| GO:0003344 pericardium morphogenesis | IMP:KEEP_AS_NON_CORE | — |
| GO:0006351 DNA-templated transcription | IMP:MODIFY | — |
| GO:0006355 regulation of DNA-templated transcription | IEA:ACCEPT IMP:ACCEPT |
IEA:ACCEPT |
| GO:0006357 regulation of transcription by RNA polymerase II | IBA:ACCEPT | IBA:ACCEPT |
| GO:0007389 pattern specification process | IBA:KEEP_AS_NON_CORE | IBA:KEEP_AS_NON_CORE |
| GO:0007507 heart development | IGI:ACCEPT IMP:ACCEPT |
IMP:ACCEPT |
| GO:0009653 anatomical structure morphogenesis | IEA:ACCEPT | IEA:ACCEPT |
| GO:0009887 animal organ morphogenesis | IMP:ACCEPT | — |
| GO:0021554 optic nerve development | IGI:KEEP_AS_NON_CORE | IGI:KEEP_AS_NON_CORE |
| GO:0033339 pectoral fin development | IMP:ACCEPT | IMP:ACCEPT |
| GO:0035050 embryonic heart tube development | IMP:ACCEPT | — |
| GO:0035118 embryonic pectoral fin morphogenesis | IMP:ACCEPT | — |
| GO:0035138 pectoral fin morphogenesis | IMP:ACCEPT | — |
| GO:0036302 atrioventricular canal development | IGI:ACCEPT | — |
| GO:0045893 positive regulation of DNA-templated transcription | IDA:ACCEPT IEA:ACCEPT IMP:ACCEPT |
IEA:ACCEPT |
| GO:0045944 positive regulation of transcription by RNA polymerase II | IDA:ACCEPT | — |
| GO:0048794 swim bladder development | NOT IGI:ACCEPT NOT IMP:ACCEPT |
NOT IGI:ACCEPT NOT IMP:ACCEPT |
| GO:0055007 cardiac muscle cell differentiation | IGI:KEEP_AS_NON_CORE | — |
| GO:0060042 retina morphogenesis in camera-type eye | IGI:KEEP_AS_NON_CORE | IGI:KEEP_AS_NON_CORE |
| GO:0060174 limb bud formation | IMP:ACCEPT | — |
| GO:0060429 epithelium development | IEA:MARK_AS_OVER_ANNOTATED | IEA:MARK_AS_OVER_ANNOTATED |
| GO:0061026 cardiac muscle tissue regeneration | IMP:KEEP_AS_NON_CORE | — |
CC
| Term | tbx5a | tbx5b |
|---|---|---|
| GO:0000785 chromatin | IBA:ACCEPT | IBA:ACCEPT |
| GO:0005634 nucleus | IBA:ACCEPT IDA:ACCEPT IEA:ACCEPT IEP:ACCEPT ISS:ACCEPT |
IBA:ACCEPT IEA:ACCEPT |
| GO:0005737 cytoplasm | IEA:KEEP_AS_NON_CORE ISS:KEEP_AS_NON_CORE |
IEA:KEEP_AS_NON_CORE |
| GO:0015629 actin cytoskeleton | IPI:KEEP_AS_NON_CORE | — |
| GO:0032991 protein-containing complex | ISS:MARK_AS_OVER_ANNOTATED | — |
| GO:0032993 protein-DNA complex | ISS:KEEP_AS_NON_CORE | — |
Core molecular functions
- tbx5a: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
- tbx5b: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific