tp53bp2a / tp53bp2b: annotation comparison
Generated by projects/DANRE_DUPLICATION/scripts/compare_pair.py; do not edit by hand.
Proteins
| tp53bp2a | tp53bp2b | |
|---|---|---|
| UniProt | F1R419 | F1QWN1 |
| Length (aa) | 1060 | 1063 |
Global alignment (BLOSUM62, gap -10/-0.5): 60.9% identity, 72.9% similarity over 1100 alignment columns.
Existing annotations by term
Cells show evidence:action. — means the copy has no annotation to that exact term (it may still have a parent or child term).
MF
| Term | tp53bp2a | tp53bp2b |
|---|---|---|
| GO:0002039 p53 binding | IBA:ACCEPT IEA:ACCEPT |
IBA:ACCEPT IEA:ACCEPT |
| GO:0043560 insulin receptor substrate binding | IPI:NEW | IPI:NEW |
BP
| Term | tp53bp2a | tp53bp2b |
|---|---|---|
| GO:0003341 cilium movement | — | IMP:UNDECIDED |
| GO:0007165 signal transduction | IEA:MODIFY | IEA:MODIFY |
| GO:0042981 regulation of apoptotic process | IEA:ACCEPT | IEA:ACCEPT |
| GO:0043009 chordate embryonic development | IMP:MODIFY | IMP:MODIFY |
| GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction | IMP:ACCEPT | IMP:ACCEPT |
| GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator | IBA:ACCEPT | IBA:ACCEPT |
CC
| Term | tp53bp2a | tp53bp2b |
|---|---|---|
| GO:0005634 nucleus | IBA:KEEP_AS_NON_CORE IEA:KEEP_AS_NON_CORE |
IBA:KEEP_AS_NON_CORE IEA:KEEP_AS_NON_CORE |
| GO:0005737 cytoplasm | — | IDA:ACCEPT IEA:ACCEPT |
| GO:0005912 adherens junction | IBA:ACCEPT | IBA:ACCEPT |
| GO:0048471 perinuclear region of cytoplasm | IBA:KEEP_AS_NON_CORE | IBA:KEEP_AS_NON_CORE |
Core molecular functions
- tp53bp2a: GO:0043560 insulin receptor substrate binding; GO:0002039 p53 binding
- tp53bp2b: GO:0043560 insulin receptor substrate binding; GO:0002039 p53 binding