PN row 1: Mitochondrial proteostasis | Protein transport | Inner membrane import | TIMM22 complex
UniProt: Q53H12
In branches: MI
PN-node mapping records (path + ancestors):
[type] Mitochondrial proteostasis|Protein transport|Inner membrane import|TIMM22 complex
status=mapped scope=ok_for_propagation_to_go GO=[GO:0042721 TIM22 mitochondrial import inner membrane insertion complex]
rationale: This PN type captures TIMM22-complex components responsible for a specific inner-membrane import route. The GO cellular-component term for the TIM22 insertion complex is an appropriate propagation target.
[group] Mitochondrial proteostasis|Protein transport|Inner membrane import
status=context_only scope=too_broad_to_propagate GO=[GO:0044743 protein transmembrane import into intracellular organelle]
rationale: In 4.3.11, inner-membrane import is a group that covers TIM22, TIM17/23, PAM-associated matrix import, and related inner-membrane sorting routes. The source is useful context for mitochondrial protein import, but protein insertion into mitochondrial inner membrane is too specific for all descendants because reviewed TIM23/PAM components include matrix-import motor and gatekeeper roles. Propagation should come from narrower child nodes such as TIM22 complex, TIM23 complex, or OXA1L-mediated insertion.
[class] Mitochondrial proteostasis|Protein transport
status=mapped scope=ok_for_propagation_to_go GO=[GO:0015031 protein transport]
rationale: The PN mitochondrial Protein transport class groups protein-targeting and import pathways into mitochondria. GO protein transport is the appropriate propagation target, while the source class remains mitochondria-specific and broader than any single GO transport subtype.
[branch] Mitochondrial proteostasis
status=no_mapping scope= GO=[]
rationale: Reviewed as a top-level PN branch. This is a systems/taxonomy umbrella, not a direct GO assertion; narrower child curations carry any propagating GO mappings.
Projected GO annotations (2)
GO:0015031 protein transport | scope=ok_for_propagation_to_go | goa_status=new_to_goa | from=Mitochondrial proteostasis|Protein transport