PN row 1: Cytonuclear proteostasis | Chaperone | small HSP system | small HSP
UniProt: Q12988
In branches: CY, MI
PN-node mapping records (path + ancestors):
[type] Cytonuclear proteostasis|Chaperone|small HSP system|small HSP
status=mapped scope=ok_for_propagation_to_go GO=[GO:0044183 protein folding chaperone]
rationale: This PN type denotes small heat-shock chaperones. Protein folding chaperone is the appropriate shared molecular-function term.
[group] Cytonuclear proteostasis|Chaperone|small HSP system
status=no_mapping scope= GO=[]
rationale: Reviewed as a narrower taxonomy bucket that is already covered by a curated parent mapping or by gene-level annotations. No additional direct GO mapping is appropriate from this node.
[class] Cytonuclear proteostasis|Chaperone
status=no_mapping scope= GO=[]
rationale: Reviewed as a broad PN category rather than a specific GO class. The member genes span multiple activities, complexes, or contexts, so propagation from this node would overstate the shared biology; use narrower child or gene-level curations.
[branch] Cytonuclear proteostasis
status=no_mapping scope= GO=[]
rationale: Reviewed as a top-level PN branch. This is a systems/taxonomy umbrella, not a direct GO assertion; narrower child curations carry any propagating GO mappings.
PN row 2: Mitochondrial proteostasis | Chaperone | small HSP
UniProt: Q12988
In branches: CY, MI
PN-node mapping records (path + ancestors):
[group] Mitochondrial proteostasis|Chaperone|small HSP
status=mapped scope=ok_for_propagation_to_go GO=[GO:0044183 protein folding chaperone]
rationale: This PN group denotes mitochondrial small heat-shock chaperones. Protein folding chaperone is the appropriate shared molecular-function term.
[class] Mitochondrial proteostasis|Chaperone
status=no_mapping scope= GO=[]
rationale: This PN class is too heterogeneous for a single safe GO mapping. In the workbook it mixes HSP70, HSP60, and HSP90 systems, small intermembrane-space chaperones, membrane-protein chaperones, and other mitochondrial-specific factors.
[branch] Mitochondrial proteostasis
status=no_mapping scope= GO=[]
rationale: Reviewed as a top-level PN branch. This is a systems/taxonomy umbrella, not a direct GO assertion; narrower child curations carry any propagating GO mappings.