PN placement: row1 ER proteostasis|Chaperone|HSP70 system|J-domain containing HSP70 cochaperone (GO:0030544); row2 ER proteostasis|Folding enzyme|Protein disulfide isomerases (group=mapped GO:0003756 protein disulfide isomerase activity, new_to_goa)
Consistency: Row1 is fully consistent — review and notes confirm J-domain binding of BiP/HSPA5 and GO:0030544 is in GOA (already_in_goa_exact is correct). Row2 contains a mechanistic contradiction: PN files ERdj5 under "Protein disulfide isomerases" and projects GO:0003756 (PDI = isomerase activity), but the review, notes, UniProt (RecName "ER disulfide reductase"), and literature (PMID:23769672, PMID:37739037) establish ERdj5 as a disulfide reductase (GO:0015035, EC 1.8.4.2), not an isomerase. The review correctly annotates reductase activity and never asserts GO:0003756.
PN story / NEW pressure:GO:0003756 is a verified real term but sits in the isomerase branch (GO:0016853 → GO:0016864 transposing S-S bonds), whereas GO:0015035 is in the oxidoreductase branch (GO:0016491). They are mechanistically distinct. ERdj5 removes/reduces non-native disulfides; it does not rearrange them. Projecting GO:0003756 onto DNAJC10 over-reaches and is the wrong activity. The correct, already-captured term is GO:0015035 (IDA, in GOA).
Mapping strategy: Row2 group mapping should be reconsidered for ERdj5 — the "Protein disulfide isomerases" PN group conflates reductases with isomerases. For DNAJC10 specifically the propagated term should be GO:0015035 (protein-disulfide reductase activity), not GO:0003756.
Evidence alignment: PN row carries no titles; review evidence (PMID:12411443, 18400946, 23769672, 37739037 — all verified) uniformly supports reductase + BiP co-chaperone, none supports isomerase activity. Divergence is in the PN group label, not the literature.
Verdict: Row1 consistent/captured; Row2 over-reaches (PDI isomerase ≠ ERdj5 reductase). Recommended edits: [MAP] retarget DNAJC10 row2 from GO:0003756 (PDI activity) to GO:0015035 (protein-disulfide reductase activity), or exclude ERdj5 from the "Protein disulfide isomerases" PN group as a reductase exception.