PN placement:Translation|Cytosolic translation|Nascent peptide husbandry|N-terminal acetylation of nascent peptide|NatC complex component ; PN-node mapping: subtype mapped→GO:0031417 NatC complex (ok_for_propagation); type mapped→GO:0006474 N-terminal protein amino acid acetylation (ok_for_propagation, new_to_goa)
Consistency: Strong. Deep-research notes, review YAML and PN dossier all agree NAA30 is the catalytic subunit of NatC (=NAA30+NAA35+NAA38, hMak3/hMak10/hMak31), co-translational Nt-acetylation of retained Met before bulky/hydrophobic residues, ribosome-associated. PN-node mapping (NatC complex CC; Nt-acetylation BP) matches the review's MF/CC content. No contradictions.
PN story / NEW pressure: PN projects the BPGO:0006474 (N-terminal protein amino acid acetylation) — verified real and non-obsolete via OLS; confirmed absent from NAA30 GOA (grep). The review captures the MF (GO:0004596, GO:0120518) and CC (GO:0031417) but has no BP for the acetylation process. GO:0006474 is the BP aspect, not a parent of the MF terms, so it is genuinely complementary. Conclusion: ADDGO:0006474 (involved_in) is defensible and would round out MF/BP/CC; not an over-reach for the catalytic subunit.
Mapping strategy: Sound for the catalytic subunit. Subtype→NatC complex (exact CC) and type→Nt-acetylation BP are both appropriate and not too broad (NAA30 directly performs the catalysis). No change to node mapping warranted.
Evidence alignment: Concordant. PN row carries no reference titles; review/notes anchor to PMID:19398576 (NatC characterization, hMak3 catalytic; IDA GO:0004596/GO:0031417) and PMID:37891180 (Nt-acetylation shields from degradation). Both VERIFIED in the YAML reference_review. No divergence.
Verdict: Consistent and high-quality. Optional ADD of BP GO:0006474 to the review to mirror the PN projection. Recommended edits: Add existing/new BP annotation GO:0006474 (N-terminal protein amino acid acetylation, involved_in) to NAA30 review [YAML].
2026-06-18 follow-up: Implemented the YAML edit: added GO:0006474 N-terminal protein amino acid acetylation as a NEW BP recommendation and added it to the catalytic NatC core function.