Reactome pathway alignment: glycosphingolipid_lysosomal_degradation
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Generated by ingest_reactome_pathways.py from R-HSA-1660661 using curated_slice scope.
Counts
| Measure |
Count |
| Imported events |
6 |
| Imported reaction-like events |
5 |
| Activity-level cited event matches |
6 |
| Full executor/MF matches |
2 |
| Same-reaction rows needing review |
4 |
| Reactome-only reaction-like events |
0 |
| Module-only activity Reactome IDs |
2 |
| Same-executor fuzzy links |
0 |
| Reactome-only black-box events |
0 |
Activity-Level Cited Event Matches
| Reactome ID |
Verdict |
Basis |
Node |
Annoton |
Function |
Event |
| R-HSA-1605591 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
gba_step |
gba_activity |
GO:0004348 |
GBA1:SAPC hydrolyzes GlcCer |
| R-HSA-1606564 |
reaction_id_exact |
cited_reactome_id, executor_match_exact, mf_match |
galc_step |
galc_activity |
GO:0004336 |
GALC hydrolyzes GalCer |
| R-HSA-1606602 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
asah1_step |
asah1_activity |
GO:0017040 |
ASAH1 hydrolyzes ceramide |
| R-HSA-1606807 |
same_reaction_missing_executor |
cited_reactome_id |
activator_step |
psap_activity |
GO:0030290 |
ARSA removes sulfate from PSAP(195-273):Sulfatide |
| R-HSA-1606807 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
arsa_step |
arsa_activity |
GO:0004098 |
ARSA removes sulfate from PSAP(195-273):Sulfatide |
| R-HSA-9769742 |
reaction_id_exact |
cited_reactome_id, executor_match_exact, mf_match |
smpd1_step |
smpd1_activity |
GO:0004767 |
SMPD1 converts sphingomyelin to ceramide |
Same-Reaction Rows Needing Review
| Reactome ID |
Verdict |
Basis |
Node |
Annoton |
Event |
| R-HSA-1605591 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
gba_step |
gba_activity |
GBA1:SAPC hydrolyzes GlcCer |
| R-HSA-1606602 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
asah1_step |
asah1_activity |
ASAH1 hydrolyzes ceramide |
| R-HSA-1606807 |
same_reaction_missing_executor |
cited_reactome_id |
activator_step |
psap_activity |
ARSA removes sulfate from PSAP(195-273):Sulfatide |
| R-HSA-1606807 |
same_reaction_executor_unconfirmed |
cited_reactome_id, executor_match_via_complex, mf_match |
arsa_step |
arsa_activity |
ARSA removes sulfate from PSAP(195-273):Sulfatide |
Reactome-Only Reaction-Like Events
| Reactome ID |
Verdict |
Candidate local activities |
Class |
Catalyst members |
Event |
|
|
|
|
|
|
Module-Only Activity Evidence
| Reactome ID |
Verdict |
Candidate imported events |
Node |
Annoton |
Function |
| R-HSA-1605624 |
module_only_event |
|
glb1_step |
glb1_gsl_activity |
GO:0004565 |
| R-HSA-1606312 |
module_only_event |
|
glb1_step |
glb1_gsl_activity |
GO:0004565 |