Cerebellum development module x mouse Bgee developmental expression
Generated by scripts/cerebellum_timing.py; do not edit. Bgee 15.2 stage-resolved present calls for the OMA mouse ortholog of each module participant. ✔ = expressed in the step's context at that stage; · = expressed only elsewhere at that stage; blank = no call at that stage.
Variant: declared_strict
Steps satisfiable per stage (module_logic engine)
| step |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
onset |
| anlage_allocation |
|
|
|
|
|
|
— |
| germinal_zone_lineage_specification |
|
✔ |
|
|
|
|
E10.5-E14 |
| purkinje_cell_development |
|
|
|
|
|
|
— |
| granule_cell_precursor_proliferation |
|
|
|
|
|
|
— |
| post_specification_growth_and_lamination |
|
|
|
|
|
|
— |
| regional_foliation |
|
✔ |
✔ |
✔ |
✔ |
✔ |
E10.5-E14 |
Step-onset order vs module order: 0 concordant, 0 discordant, 1 tied pairs.
Genes
| step |
gene |
context |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
| 1 anlage_allocation |
FGF8 |
UBERON:0002037 cerebellum |
· |
· |
· |
· |
|
✔ |
| 1 anlage_allocation |
GBX2 |
UBERON:0002037 cerebellum |
· |
✔ |
✔ |
✔ |
· |
· |
| 2 germinal_zone_lineage_specification |
ATOH1 |
UBERON:0006215 rhombic lip; CL:0002362 cerebellar granule cell precursor |
· |
✔ |
· |
· |
· |
· |
| 2 germinal_zone_lineage_specification |
PTF1A |
CL:0000121 Purkinje cell |
· |
· |
· |
· |
· |
· |
| 3 purkinje_cell_development |
RELN |
UBERON:0002979 Purkinje cell layer of cerebellar cortex; CL:0000121 Purkinje cell |
· |
· |
· |
· |
· |
· |
| 3 purkinje_cell_development |
RORA |
CL:0000121 Purkinje cell |
· |
· |
✔ |
✔ |
· |
· |
| 3 purkinje_cell_development |
SHH |
CL:0000121 Purkinje cell |
· |
· |
· |
✔ |
· |
· |
| 4 granule_cell_precursor_proliferation |
SMO |
UBERON:0008829 cerebellum external granule cell layer; CL:0002362 cerebellar granule cell precursor |
· |
· |
· |
· |
· |
· |
| 5 post_specification_growth_and_lamination |
DNER |
CL:0000644 Bergmann glial cell |
· |
· |
· |
· |
· |
· |
| 5 post_specification_growth_and_lamination |
FBXO41 |
UBERON:0002956 granular layer of cerebellar cortex; CL:0001031 cerebellar granule cell |
· |
· |
· |
· |
· |
· |
| 5 post_specification_growth_and_lamination |
PTPN11 |
CL:0000644 Bergmann glial cell |
· |
· |
· |
· |
· |
· |
| 6 regional_foliation |
EN1 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
| 6 regional_foliation |
EN2 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
Variant: declared
Steps satisfiable per stage (module_logic engine)
| step |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
onset |
| anlage_allocation |
|
|
|
|
|
|
— |
| germinal_zone_lineage_specification |
|
✔ |
✔ |
✔ |
✔ |
|
E10.5-E14 |
| purkinje_cell_development |
|
|
✔ |
✔ |
✔ |
✔ |
E14-birth |
| granule_cell_precursor_proliferation |
|
|
✔ |
|
|
✔ |
E14-birth |
| post_specification_growth_and_lamination |
|
|
|
✔ |
✔ |
✔ |
P0-P7 |
| regional_foliation |
|
✔ |
✔ |
✔ |
✔ |
✔ |
E10.5-E14 |
Step-onset order vs module order: 5 concordant, 3 discordant, 2 tied pairs.
Genes
| step |
gene |
context |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
| 1 anlage_allocation |
FGF8 |
UBERON:0002037 cerebellum |
· |
· |
· |
· |
|
✔ |
| 1 anlage_allocation |
GBX2 |
UBERON:0002037 cerebellum |
· |
✔ |
✔ |
✔ |
· |
· |
| 2 germinal_zone_lineage_specification |
ATOH1 |
UBERON:0006215 rhombic lip; CL:0002362 cerebellar granule cell precursor |
· |
✔ |
· |
· |
· |
· |
| 2 germinal_zone_lineage_specification |
PTF1A |
CL:0000121 Purkinje cell |
· |
· |
✔ |
✔ |
✔ |
· |
| 3 purkinje_cell_development |
RELN |
UBERON:0002979 Purkinje cell layer of cerebellar cortex; CL:0000121 Purkinje cell |
· |
· |
✔ |
✔ |
✔ |
✔ |
| 3 purkinje_cell_development |
RORA |
CL:0000121 Purkinje cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
| 3 purkinje_cell_development |
SHH |
CL:0000121 Purkinje cell |
· |
· |
✔ |
✔ |
✔ |
✔ |
| 4 granule_cell_precursor_proliferation |
SMO |
UBERON:0008829 cerebellum external granule cell layer; CL:0002362 cerebellar granule cell precursor |
· |
· |
✔ |
· |
· |
✔ |
| 5 post_specification_growth_and_lamination |
DNER |
CL:0000644 Bergmann glial cell |
· |
· |
· |
✔ |
✔ |
✔ |
| 5 post_specification_growth_and_lamination |
FBXO41 |
UBERON:0002956 granular layer of cerebellar cortex; CL:0001031 cerebellar granule cell |
· |
· |
· |
✔ |
✔ |
✔ |
| 5 post_specification_growth_and_lamination |
PTPN11 |
CL:0000644 Bergmann glial cell |
· |
· |
· |
✔ |
✔ |
✔ |
| 6 regional_foliation |
EN1 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
| 6 regional_foliation |
EN2 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
Variant: territory
Steps satisfiable per stage (module_logic engine)
| step |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
onset |
| anlage_allocation |
✔ |
✔ |
✔ |
|
|
|
E8-E10.5 |
| germinal_zone_lineage_specification |
|
✔ |
✔ |
✔ |
✔ |
|
E10.5-E14 |
| purkinje_cell_development |
|
✔ |
✔ |
✔ |
✔ |
✔ |
E10.5-E14 |
| granule_cell_precursor_proliferation |
|
|
✔ |
|
|
✔ |
E14-birth |
| post_specification_growth_and_lamination |
|
|
|
✔ |
✔ |
✔ |
P0-P7 |
| regional_foliation |
✔ |
✔ |
✔ |
✔ |
✔ |
✔ |
E8-E10.5 |
Step-onset order vs module order: 9 concordant, 4 discordant, 2 tied pairs.
Genes
| step |
gene |
context |
E8-E10.5 |
E10.5-E14 |
E14-birth |
P0-P7 |
P7-P21 |
adult |
| 1 anlage_allocation |
FGF8 |
UBERON:0002037 cerebellum |
✔ |
✔ |
✔ |
· |
|
✔ |
| 1 anlage_allocation |
GBX2 |
UBERON:0002037 cerebellum |
✔ |
✔ |
✔ |
✔ |
· |
· |
| 2 germinal_zone_lineage_specification |
ATOH1 |
UBERON:0006215 rhombic lip; CL:0002362 cerebellar granule cell precursor |
· |
✔ |
✔ |
✔ |
✔ |
· |
| 2 germinal_zone_lineage_specification |
PTF1A |
CL:0000121 Purkinje cell |
· |
✔ |
✔ |
✔ |
✔ |
· |
| 3 purkinje_cell_development |
RELN |
UBERON:0002979 Purkinje cell layer of cerebellar cortex; CL:0000121 Purkinje cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
| 3 purkinje_cell_development |
RORA |
CL:0000121 Purkinje cell |
· |
✔ |
✔ |
✔ |
✔ |
✔ |
| 3 purkinje_cell_development |
SHH |
CL:0000121 Purkinje cell |
✔ |
✔ |
✔ |
✔ |
✔ |
✔ |
| 4 granule_cell_precursor_proliferation |
SMO |
UBERON:0008829 cerebellum external granule cell layer; CL:0002362 cerebellar granule cell precursor |
· |
· |
✔ |
· |
· |
✔ |
| 5 post_specification_growth_and_lamination |
DNER |
CL:0000644 Bergmann glial cell |
· |
· |
✔ |
✔ |
✔ |
✔ |
| 5 post_specification_growth_and_lamination |
FBXO41 |
UBERON:0002956 granular layer of cerebellar cortex; CL:0001031 cerebellar granule cell |
· |
· |
· |
✔ |
✔ |
✔ |
| 5 post_specification_growth_and_lamination |
PTPN11 |
CL:0000644 Bergmann glial cell |
· |
· |
· |
✔ |
✔ |
✔ |
| 6 regional_foliation |
EN1 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
✔ |
✔ |
✔ |
✔ |
✔ |
✔ |
| 6 regional_foliation |
EN2 |
UBERON:0002037 cerebellum; CL:0000121 Purkinje cell; CL:0001031 cerebellar granule cell; CL:0000644 Bergmann glial cell |
✔ |
✔ |
✔ |
✔ |
✔ |
✔ |