pax6a / pax6b: annotation comparison
Generated by projects/DANRE_DUPLICATION/scripts/compare_pair.py; do not edit by hand.
Proteins
| pax6a | pax6b | |
|---|---|---|
| UniProt | P26630 | A0A0R4IQL7 |
| Length (aa) | 437 | 450 |
Global alignment (BLOSUM62, gap -10/-0.5): 92.7% identity, 95.1% similarity over 450 alignment columns.
Existing annotations by term
Cells show evidence:action. — means the copy has no annotation to that exact term (it may still have a parent or child term).
MF
| Term | pax6a | pax6b |
|---|---|---|
| GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding | IBA:ACCEPT | IBA:ACCEPT |
| GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific | IBA:ACCEPT IEA:ACCEPT |
IBA:ACCEPT IDA:ACCEPT IEA:ACCEPT |
| GO:0003677 DNA binding | IEA:ACCEPT | IEA:ACCEPT |
BP
| Term | pax6a | pax6b |
|---|---|---|
| GO:0001654 eye development | — | IMP:ACCEPT |
| GO:0001755 neural crest cell migration | IGI:NEW | IGI:KEEP_AS_NON_CORE |
| GO:0002088 lens development in camera-type eye | — | IMP:ACCEPT |
| GO:0002089 lens morphogenesis in camera-type eye | — | IMP:ACCEPT |
| GO:0003309 type B pancreatic cell differentiation | IBA:REMOVE | IBA:ACCEPT IMP:ACCEPT |
| GO:0003310 pancreatic A cell differentiation | — | IMP:ACCEPT |
| GO:0003311 pancreatic D cell differentiation | — | IMP:ACCEPT |
| GO:0006351 DNA-templated transcription | — | IEA:MODIFY |
| GO:0006355 regulation of DNA-templated transcription | IEA:ACCEPT | IEA:ACCEPT |
| GO:0006357 regulation of transcription by RNA polymerase II | IBA:ACCEPT | IBA:ACCEPT |
| GO:0007420 brain development | IBA:ACCEPT | IBA:ACCEPT |
| GO:0007423 sensory organ development | IBA:ACCEPT | IBA:ACCEPT |
| GO:0008284 positive regulation of cell population proliferation | IMP:MODIFY | — |
| GO:0009952 anterior/posterior pattern specification | IEA:KEEP_AS_NON_CORE | IEA:KEEP_AS_NON_CORE IMP:KEEP_AS_NON_CORE |
| GO:0010468 regulation of gene expression | — | IGI:KEEP_AS_NON_CORE |
| GO:0021538 epithalamus development | IGI:NEW | IGI:KEEP_AS_NON_CORE |
| GO:0021986 habenula development | IMP:NEW | — |
| GO:0030154 cell differentiation | IEA:KEEP_AS_NON_CORE | IEA:KEEP_AS_NON_CORE |
| GO:0030900 forebrain development | IBA:ACCEPT | IBA:ACCEPT |
| GO:0030902 hindbrain development | IEA:KEEP_AS_NON_CORE | IEA:KEEP_AS_NON_CORE IMP:KEEP_AS_NON_CORE |
| GO:0035883 enteroendocrine cell differentiation | — | IMP:ACCEPT |
| GO:0042670 retinal cone cell differentiation | IMP:MARK_AS_OVER_ANNOTATED | — |
| GO:0045944 positive regulation of transcription by RNA polymerase II | IEA:ACCEPT | IDA:ACCEPT IEA:ACCEPT |
| GO:0048593 camera-type eye morphogenesis | IEA:ACCEPT | IEA:ACCEPT |
| GO:0060041 retina development in camera-type eye | IBA:ACCEPT | IBA:ACCEPT |
| GO:0060221 retinal rod cell differentiation | IMP:REMOVE | — |
| GO:0061303 cornea development in camera-type eye | — | IMP:ACCEPT |
| GO:0090104 pancreatic epsilon cell differentiation | — | IMP:ACCEPT |
| GO:2000179 positive regulation of neural precursor cell proliferation | — | IMP:NEW |
CC
| Term | pax6a | pax6b |
|---|---|---|
| GO:0005634 nucleus | IBA:ACCEPT IEA:ACCEPT |
IBA:ACCEPT IEA:ACCEPT |
Core molecular functions
- pax6a: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
- pax6b: GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific; GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific