PN placement:UPS|Proteasome and associated proteins|proteasome regulatory particle subunit|base, nonATPase|PRU, DEUBAD (row 1) and UPS|Ubiquitin and UBL binding|proteasomal subunits|regulatory particle|idiosyncratic Ub binding / PRU (row 2) ; PN-node mapping: type base, nonATPase=mapped→GO:0008540 base subcomplex (more_specific_than_existing_goa); group regulatory particle subunit=mapped→GO:0005838 regulatory particle; group proteasomal subunits=mapped→GO:0000502 proteasome complex (already_in_goa_exact); ub-binding classes=context_only.
Consistency: Deep research (manual), notes, review YAML, and all PN-node mappings are mutually consistent. ADRM1/Rpn13 is a 19S regulatory-particle ubiquitin receptor (Pru domain) that binds Rpn2/PSMD1 and recruits/activates the UCHL5/UCH37 DUB (PMID:16990800, 17139257, 18497817, 20471946, 29636472). No contradictions.
PN story / NEW pressure: PN's key non-trivial assertion is base- (not lid-) subcomplex membership (GO:0008540, OLS-verified real). GOA carried an IBA GO:0008541lid subcomplex annotation; the review MODIFIES it to GO:0008540 base subcomplex, citing Rpn13/Rpn10 as base ubiquitin receptors (PMID:29636472, 33729481) — exactly executing the PN projection. Other projected terms (GO:0000502, GO:0005838) already captured/entailed. Review also adds specific MFs beyond PN (GO:0035800 deubiquitinase activator via MODIFY of GO:0061133; GO:0043130 ubiquitin binding; GO:0070628 proteasome binding; GO:1990381 ubiquitin-specific protease binding). Conclusion: PN base-subcomplex correction = legitimate ADD/MODIFY, executed; rest already captured.
Mapping strategy: This gene confirms the base-subcomplex mapping (lid→base is a genuine GOA correction, not over-reach). All PN scopes are correctly leveled (CC membership terms, no over-broad propagation). No change needed.
Evidence alignment: PN references (PMID:19145068, 19489727, 18497827, 32160516) overlap the review's Rpn13/Pru/DEUBAD evidence base; the review additionally uses the foundational identification and structural papers (16990800, 17139257, 18497817, 20471946, 29636472, 33729481). Strong overlap, review enriched — no conflict.
Verdict: Fully consistent; PN's lid→base correction and regulatory-particle/proteasome-complex mappings all validated and executed in the review. Recommended edits: none (mapping and review aligned).