PN placement: 2 rows, ALP (identical structure to ARL8A). (1) …Localization of the autophagosome|Movement of autophagosomes along microtubules|HOPS-BORC complex bridging; (2) …Autophagosome-lysosome docking|HOPS-BORC interaction mediator. PN-node mapping: localization group + movement/bridging leaves=mapped→GO:0061906 autophagosome localization (new_to_goa); docking nodes=context_only→GO:0061909; class=context_only→GO:0016236.
Consistency: Consistent, with deliberate PN-vs-review divergence on GO:0061906. DR ↔ notes ↔ YAML agree: ARL8B is the better-characterized paralog — lysosomal small GTPase recruiting SKIP/PLEKHM2-kinesin (anterograde), HOPS/VPS41 (fusion), RUFY3/4 and DENND6A/Rab34/RILP (retrograde).
PN story / NEW pressure: PN's projected term GO:0061906 autophagosome localization (verified real, new_to_goa): review DECLINES — ARL8B drives lysosome positioning and autophagosome-lysosome fusion/cargo delivery, not direct positioning of autophagosomes as cargo. The autophagy role IS already captured by the existing GO:0061909 autophagosome-lysosome fusion (IMP, PMID:28325809) which the review ACCEPTs. So the genuine autophagy story is already in GOA via fusion, and GO:0061906 over-reaches. Conclude: already-captured (fusion) + GO:0061906 not supported.
Mapping strategy: Same as ARL8A — mapping flagged manual_gene_level_review_required; gene-level review declines GO:0061906 projection. Right process family, wrong cargo organelle; shared target should remain lysosome localization (GO:0032418) / existing fusion term.
Evidence alignment: PN cites the same three titles as ARL8A (Arl8 review; BORC; RUFY3/4=PMID:35314674). Review anchors PMID:16537643, 25898167 (BORC), 22172677 (SKIP/kinesin), 21802320 (VPS41/HOPS), 28325809 (PLEKHM1/fusion), 35314674 (RUFY3/4); DR added PMID:38296963 (DENND6A), 38128568 (BORCS8). REF ISSUE flagged in review: seeded GO:0007059 chromosome segregation cites PMID:14871887 (a Drosophila Topors paper, wrong gene) — review retains term as non-core (supported by GIE PMID:15331635) and flags the mismatch with a reference_review + suggested correction.
Verdict: Consistent; PN GO:0061906 over-reaches; autophagy role already captured via GO:0061909 (ACCEPTed). REF mismatch (PMID:14871887) correctly flagged, not removed.
Recommended edits: none to ARL8B-ai-review.yaml (it already flags both issues). [MAP] do not propagate GO:0061906 to ARL8B (autophagy role captured by GO:0061909). [REF] PN/curators: correct GO:0007059 origin reference PMID:14871887 → PMID:15331635 (GIE/ARL8 study).