PN placement: two ALP rows — ALP|Pre-initiation autophagy signaling|mTORC1 pathway, upstream|Nutrient sensing|V0 lysosomal v-ATPase proton pump component and ALP|Lysosomal catabolism|Regulation of lysosomal environment|Lysosomal acidification|V0 lysosomal v-ATPase proton pump component ; PN-node mapping: V0 subtype leaves mapped/ok_for_propagation → GO:0046610 (lysosomal V0 domain) and GO:0033179 (V0 domain); Lysosomal-acidification type mapped/ok_for_propagation → GO:0007042; mTORC1/nutrient-sensing ancestors no_mapping; Pre-initiation class context_only/too_broad (GO:0010506).
Consistency: Consistent. Notes, review, PN row, and PN-node mapping all converge on the V0-sector lysosomal V-ATPase identity. The review adds exactly the three projected terms at their mapped levels and explicitly declines to promote the broader nutrient-sensing/autophagy context. No contradictions.
PN story / NEW pressure: The lysosomal-specific terms were genuinely absent from ATP6V0A2 GOA (which had only broader GO:0007035 vacuolar acidification and GO:0033179/GO:0000220 V0-domain). Review adds GO:0007042 lysosomal lumen acidification (NEW) and GO:0046610 lysosomal V0 domain (NEW). I verified both are real, non-obsolete GO terms via OLS. These are defensible ADDs (more specific children of existing annotations), supported by V0-subunit identity plus lysosomal-membrane proteomics (PMID:17897319). The PN nutrient-sensing/mTORC1 story correctly does NOT generate a NEW term — review leaves it as a suggested_question/experiment only.
Mapping strategy: No change warranted. Subtype-level ok_for_propagation and the conservative no_mapping/context_only ancestors are right; broad mTORC1 container is correctly not propagated (matches TOMM20/HSPA8 "too broad" precedent).
Evidence alignment: Divergent by design. PN cites review-article titles (mTORC1, SEA/GATOR, V-ATPase structure, neurodegeneration); the review's load-bearing PMIDs are independent primary/structural sources (16415858 ARNO endosome, 33065002 human V-ATPase cryo-EM, 32001091, 17897319 lysosomal proteomics, 28296633 iron/HIF). Only the V-ATPase-structure theme overlaps conceptually.
Verdict: Consistent; both lysosomal NEW terms are verified real, defensible ADDs; PN nutrient-sensing context correctly not propagated. No edits required.