PN placement:Nuclear proteostasis|Chaperone|Histone chaperone ; PN-node mapping: Histone-chaperone group→GO:0140713 histone chaperone activity (new_to_goa). Chaperone class + NU branch = no_mapping.
Consistency: Strong. Review, notes, PN annotation and node mapping all agree CHAF1A (p150) is the large subunit of the CAF-1 H3-H4 histone chaperone, depositing H3.1-H4 in replication-coupled nucleosome assembly. The review already carries GO:0140713 "histone chaperone activity" as a NEW (IC) annotation — exactly matching the PN projection. No contradictions.
PN story / NEW pressure: PN projects GO:0140713 (verified real; in CHAF1A/B reviews already) as new_to_goa — confirmed: GOA captures histone interactions only as bare protein binding / chromatin binding, with no MF histone-chaperone term. Already independently flagged ADD in the review (NEW GO:0140713, plus NEW GO:0042393 histone binding and GO:0006334 nucleosome assembly). PN and review converge; nothing over-reaches.
Mapping strategy: Node mapping is correctly placed at the "Histone chaperone" group (narrower than generic "Nuclear proteostasis"/"Chaperone"), aligning to a precise MF (GO:0140713) rather than a broad process — appropriate, not TOMM20/HSPA8-style over-broad. No change needed.
Evidence alignment: PN row carries no explicit reference list, but the projected MF rests on the same CAF-1 biology the review documents with PMID:8858152, PMID:14718166, PMID:7600578, PMID:21570500 (direct H3/H4 binding). Concordant; no divergence.
Verdict: CONSISTENT — PN GO:0140713 already captured by the review's NEW annotation. Recommended edits: none (review and PN aligned).